skysight-inc/HackerNews huggingface dataset:
Linux distributions just have a different security model, based on trust. Maintainers form with developers a chain of trust from the repo to your machine.

Windows and MacOS on the other hand have an untrusted security model, everything is assumed to be potentially dangerous.

Security isn't just about how the code behaves.
you could say today was a good day...
This is why I make sure my personal blog redirects to https, and why I typically install things like "https everywhere" browser extensions.

I know this kind of stuff happens, and I don't want to waste time tracking it down and shaming people for doing it.
Ok great. So what's the price?

Drug X was funded for development for $XXX million because it was perceived to have a strong positive expected ROI dependent on selling the drug for $Y leading to an expected value of $ZZZ million.

If you're offering $ZZZ million for it then the drug companies won't complain but you're just having the public pay the total cost up front. If you're offering substantially less than $ZZZ million, then the drug company will not invest $XXX million because you've just slashed he potential ROI.
Haven't used BeOS, but to clarify, I do have issues with Windows and performance, especially general input latency and responsiveness when compared to Linux, as I use both daily. But overall I think it's decent, and at the very least, not the fault of the language used, but more about legacy issues and technical debt. Anyone having worked with winapi and mfc knows the codebase is a mess.
I'm against such devices for few reasons:

- the very first issue is weather. Sometimes it rain, sometimes snow, sometimes it's too hot and so on, open-air travel under this very common weather condition is far from being nice, so they can be used only a subset of the year, but to be usable you need to be in a dense area for all the year, meaning you'll have another mean of transport witch tend to be underutilized and does not offer comfy condition as well because of city density, meaning when it rain the traffic skyrocket;

- they encourage producing more waste, yes, you read it correctly: you use something not suited to have anything but yourself, so you'll probably eat ready made packed food and than drop the package, you can't buy large quantities so again more package. Actual narrative sell the city as green, but it's only dollar-green, not spring grass green.
If staging is sometimes debugged in sorrow, it can also take place in joy, for the struggle itself to release to prod is enough to fill a dev's heart.

Lagniappe: https://existentialcomics.com/comic/29
Restaurants fail very differently from drug trials.

They run at some % loss for a while until money or investor patience runs out.

A drug trial that fails can be a 10 year process of shoveling money in a pit, none of it to be ever seen again.

It's a businesses famous for its low succes rates, which can be from start to end less than 1 in 100.

Drug companies need to offer those who provide the capital to run these experimental projects at huge losses for years a way to recoup their losses - otherwise nobody would be willing to fund the effort.

The way to do that is patent and charge absurdly high prices for those few succesfull drugs that are developed for as long as you can.
> I am close to writing a browser extension that does a find and replace to reverse change these imposed, humourless, coddled changes.

I will be your first paying customer
https://github.com/smarr/RoarVM is the main thing that comes up when trying to learn about this, and it hasn't been touched in over 10 years. I have also seen people working on spawning child VMs to handle parallelism, though unfortunately I don't have links to those discussions immediately at hand. It seems like perhaps an unnecessarily heavyweight approach, too, not a canonical solution that you would want to use in production.

I assume that step 1 towards parallelism, at least on the image side, would be going through the class library and making sure everything is thread-safe. I'd love to know where one would even get started with that effort. The Roar project claims to support Pharo 1.2, which doesn't seem to be very far after they forked from Squeak, but obviously a lot has changed since then. And the challenge is that Pharo is still rapidly developing all the overhauled classes that distinguish it from Smalltalk-80.

Meanwhile, if I want to play with parallel image/REPL-based programming, I can go over to Common Lisp and, while lacking an equally coherent GUI, be able to load up bordeaux-threads and off I go.
Why would that be hard? Once you're fluent in it development in Pharo is very, very fast, you can build a GUI application while a prospect or customer is watching and supplying inputs about what they need.

Many companies that buy software don't care about programming languages, they care about functionality and price. With Pharo you can show them immediately what the application could look like and how their processes could be implemented. Fast development means you can sell at a lower price and reach customers that can't afford more 'classic enterprise'. You can also reach customers that do work in quickly changing regulatory environments, like insurance.

When you've banged out the frontend and some logic you return to your office and
figure out things like database schema.

Pharo is specifically designed for commercial and industrial applications and not as a research environment. Partnering with private capital has been one source of funding for the project.
Non-Intrusive Load Monitoring Based on Multiscale Attention Mechanisms
> Super cool to see MZ initials, which are for Mark Zbikowski. They are still to this day at the beginning of every Windows executable/PE file.

Another is "PK" as found in the header of ordinary .zip files, after its creator Phil Katz (RIP).

https://en.wikipedia.org/wiki/Phil_Katz
With system-default code pages on Windows, it's not only platform-dependent, it's also System Locale dependent.

Windows badly dropped the ball here by not providing a simple opt-in way to make all the Ansi functions (TextOutA, etc) use the UTF-8 code page, until many many years later with the manifest file. This should have been a feature introduced in NT4 or Windows 98, not something that's put off until midway through Windows 10's development cycle.
At least not to support it and to foster local development.
150 billion in the cap isn't free cash flow.

The Fed rate spread is the difference between investing in a company and giving it to the Feds. I'm sure you've heard of "the end of easy money" and articles about if your world view was created by ZIRP. Of course another important rate is that between your profits and the inflation rate. i.e are you actually making money or running on a treadmill

Have you heard of Google, Apple, Microsoft, or Exxon, Facebook, Nvidia?

And that profit is almost nothing although the ratio is 1% into okay

Municipal broadband is a good thing. It keeps the money home. It can be successful. It's the sort of thing that's fine with very long term loans and the associated horizons

In fact most of Comcasts issues are TV related

Municipal broadband=okay
Overbuilding = very terrible idea for anyone trying to make money.

It's like trying to turn a profit in Ashburn selling carrier services where Transit is cheaper than peering
I agree with this, but I don't think dynamic types is the only solution. Something like Roc[0] strikes a better balance: it gives you a flag for development, and when enabled, all compilation errors become warnings. The compiler substitutes every function it couldn't compile with one that panics at runtime.

[0] https://www.roc-lang.org/
YMMV, but I find C# and TypeScript to have a "Goldilocks" mix of OOP and FP that you can take advantage of the strengths of each where it makes sense.
They recently became a member of PQCA, too.

Disclosure: I work for LF, assigned to PQCA.

https://pqca.org/#members
https://veilid.org/
https://github.com/pqca
I tend to see it the opposite way. Yes men are the ones who enable dictators (also cult leaders). Perhaps that's what you actually meant?
You say all this, while the literal title of the article you're commenting on is "The cost of developing new drugs may be far lower than industry claims".

I think this comment perfectly proves that this is relevant.

Manufacturing is quite relevant. If the actual cost of "discovered and proved effective" is far lower than claimed, then manufacturability becomes a concern. If the cost of discovery and proven effectiveness is borne by governments and universities, then the manufacturing is the only cost borne by the pharmaceutical companies.
I'd drop 600 in a bill in a special occasion with a somewhat good wine. But never for a reservation.
I would have like Microsoft to buy it.
Of course it does. Pretty much every FAANG, and many smaller ones, have teams for every programming language they consider important. Google has C++, Rust, Python, Java, JavaScript, and others (although I've heard that several of these teams were hard it in this round.)

To take a basic example: Google has a team that works inside LLVM and Clang to improve the code it produces for Google's specific workloads. (Often these help all of LLVM's clients.) But if this team is able to make a search query faster by even 0.01% a year, at Google scale that saves literally millions of hours in compute across Google's fleet. And millions of hours of compute is millions of dollars in power, space, and need to expand.

This is true of all the other language teams at Google too.

The Python team builds a better python by fixing upstream bugs, reducing the memory it consumes and so on. It upgrades the internal installation of Python to the newest versions, ensuring that the upgrade is smooth and doesn' break the using teams.

It contributes proposals for language features to upstream, ensuring that Google's use cases are at least considered.
People don't realize how powerful and scary suppression of speech is, and how much it skews international opinion.

My mother, who moved out of Iran right before the revolution _still_ lowers her voice when talking about certain subjects of Iran. When no one else is in the room, in the United States of America. It's deeply engrained in her mind.

It's very refreshing to hear this man's opinion. But remember, this is rare. This man could have died on one of the many times when he was protesting hamas. Some of his friends were not so lucky. We are lucky to be hearing his voice.
I do understand the problem, I'm curious if spawn would resolve it.

spawn (in the major executors at least) behaves as though it spawns a new thread to poll on. Therefore work does get underway even if callsite poll is never called, and the callsite only checks the status of the thread/task.

https://tokio.rs/tokio/tutorial/spawning
You may not mean this, but this comment really comes off as racist to me. It takes conscious effort to read it through any other lens. I’ll consider that this could be a me-problem.
If you read the document, the allegation that they made false statements remains unproven. They admit only to not being able to support the claims with evidence other than the original allegations.

The original source of the accusations that they were supporting in the open letter is also notably not named in the suit.

In most court proceedings, it must be positively proven ("beyond a reasonable doubt" in some cases, "by the preponderance of the evidence" in others) that you committed the crime or tort in question. That's a good requirement, and English defamation law is a glaring exception.
As a non-game dev who uses Rust and Elixir, Rust wouldn't be my first pick for a large gamedev studio for multiple reasons. As for alternatives worth evaluating: Crystal, Cython (compiled Python), or Nim could result in increased gamedev productivity over C++ or C#. Maybe even Go because the iteration and compile times are very fast, and the learning curve is very low.
Tesla among electric carmakers forced to cut prices as market stalls
Both my grandparents died a year ago and with one Catholic and the other Lutheran the food looked similar but tasted oh so different. The Catholic food was decent. The Lutheran food, the turkey sandwiches, the buns/rolls, the gingersnap and whole-date-filled cookies were, forgive me: to die for. Everything seemed to be made from scratch and it made me feel love for the elder women, for how special they treated their job that day. I want my friends and family to remember me by the good food they had at my funeral.
I've considered something like this for years. A simple, casual, social space to just decorate, hang out, do basic stuff like what you outline. I think there's a lot of potential there! Not so much money though, I imagine...
The S.

“Its own bill for landmark trialS of a four-drug combination treatment for drug-resistant tuberculosis came to €34m (£29m)”

You’re also looking at the cost from from 2015 to 2016 where a single phase 3 trial was already 20m and $41,117 per patient. https://www.linkedin.com/pulse/clinical-trial-budget-example...
Try this:

https://lwn.net/SubscriberLink/970565/ac5ffc2e9ad20f1e/
Nil in go is my biggest gripe with the language. Why keep repeating “the billion dollar mistake” in a relatively newly designed language??
suppose we design a reasonable experiment here, like taking a random sample of teenagers and mitigating for anonymity concerns. are you seriously claiming that this would show an increase after the ban?

or to put it another way --- the phenomenon you point to is real but completely swamped by the more direct impacts
Only if you get sick from it
So, if "gaming industry" now means the video games industry, what do we now call the gaming industry? https://fastercapital.com/content/Gaming-industry--EGM--A-Ga...
Well, it doesn't necessarily have to be 10 or 20 years long, all it takes is for the timeframe to overlap with a certificate being revoked, I guess. Process lifetimes of a few months are definitely not uncommon. Anyway, I can see the tradeoff. There just needs to be a mechanism to disable this performance optimization, or to invalidate the cache (e.g. periodically).
The difference between the conflict in Palestine and elsewhere is antisemitism.

You'd never see a any level of this **** for any conflict unless people are drafted
Yeah, that Switch support was added by the homebrew side of the fence though so I don't know if it's something that developers would be able to use in an officially licensed game. Nintendo might not care so much as long as the game works, as mentioned it's Sony in particular that I've heard is picky about which compilers their developers use.
>I don't get it, what's the point of type checking if not to reject invalid programs

It can take longer to think about how to properly type instead of just writing some code, testing it out, and immediately seeing if something is wrong. You also often get into a situation where linters who like to act like type-systems give you arcane errors (looking at you TypeScript).

In the moment I just want to move some data around and quickly try out an idea, I don't need it to be resilient or perfect.
It’s kind of funny, now when I have a programming question I find myself going straight to the documentation which is a better habit than searching anyway. By the time I would have combed through search results, blogs, and stack overflow to find a relevant answer, I might as well have just read a few pages in the docs and gotten a more complete knowledge of the topic.

I think of it as my personal journey to “RTFM”. I now understand why people are so strict about that. To be fair though, I haven’t really dabbled into alternative search engines much yet.
Just waiting for someone to write a 5000 word essay on why they are moving from Rust to do data science stuff. Totally puzzled by everyone trying to get on to the Rust bandwagon on DS/DE, when being able to iterate and make changes fast is why Python rules even though it is dog slow.
Show HN: I made a web app that streamlines collecting your customers' feedback
I realized how important and crucial it is to collect feedback in order for your business/product to grow a few months ago, and with that, coupled with my journey to freedom(launching startups) I decided to develop this app!

Feedbackr: Your shortcut to invaluable insights. Effortlessly collect feedback from customers with a few clicks, empowering your business to thrive.
Rust also is opinionated that you don't want to write shared libraries or plugins. You can do both, but only if you drop down to memory unsafe C interfaces. The default is statically compile all applications into one program. Rust also really wants you do to use their build system and package manager, you can avoid both but everything will fight you.
The dead sibling comment really exposes how a good fraction of people in the western world think.

But truly greed was the real primary motivator of technological progress for the past centuries. Not the desire to benefit humanity.

They say greed kills the greedy person.
Isn't it partly an artificial problem created by export regulations? US had soft-restricted civilian ownership of missile-related technologies by controlling exports and inflating prices. But none of it applies to DJI drones somehow, so it wins.
Yeah but you could theoretically turn off Location services and then the cell network may not be able to tell if you're at the doctors or at the McDonalds next door so it still offers some (limited) privacy.
> Congress shall make no law respecting an establishment of religion, or prohibiting the free exercise thereof; or abridging the freedom of speech, or of the press; or the right of the people peaceably to assemble, and to petition the Government for a redress of grievances."

> Not seeing exceptions for a tit for tat trade embargo or a Chinese company here.

It's not that simple. I don't see any exceptions for laws against defamation, child porn either, or limits on foreign ownership of TV stations, yet they're there.
Neither rain nor a bit of snow are a huge problem for commuting on an e-vehicle. In some countries even riding on regular bikes in the snow is perfectly normal. So it’s more of a people issue than a device issue.
I've had firearms stolen from my luggage on 3 different occasions. SJU was the common denominator each time. They were small handguns. They just took the entire case. Even damaging my luggage when I tried to attach the case to my luggage.
Amongst the worst, most opaque UX gestures I’ve ever seen. Up there with press and hold the space button to scroll in text fields on iOS.
@moderator this should be replaced with the post link.
Well, different anyway.
Which is basically abandoned. I think there were some talks with local authorities to recover it, but I don't think it will happen in my lifetime.
The US has seen evidence of China attempting to influence upcoming elections
Then use a password manager that allows it
It’s unlikely to improve anytime soon, and there are no indications that Rust will be the future of game programming.
The smartest thing we should do is make it profitable to build software and make it not at all profitable to save millions of lives. If we do it that way, people will work on the latter to the exclusion of the former. In fact, the more unprofitable we make the latter, the more of it we'll get.
A few months back, it struck me just how vital feedback is for fueling business growth. Fueled by this realization and my entrepreneurial journey, I set out to create this app, aiming to streamline the feedback collection process.
So if I call some Sports Medicine doctors, then advertisers will think I'm a cool, active person.
> I'd expected some AAA title to be written in Rust by now.

Why? Those kinds of game engines are enormous amounts of code, and there's little incentive to rewrite.

I do strongly disagree that we aren't ever going to see large-scale game development in Rust; it just takes time. Whether games adopt an engine is largely about that engine's maturity rather than anything about the language. Bevy is quite young; 0.13 doesn't even have support for animation blending yet (I landed that for 0.14).
Support for the TSO memory model on Arm CPUs
The government was paying just Pfizer like 50bn a year for Covid vaccines, I’m sure if you add up all the manufacturers they were easily paying 100bn a year from 2021-2023. I don’t have all the math but I am guessing it ended up costing at least $500/yr to vaccinate a person.

That is a long ways from free, there is just the bit of abstraction that allows corporations to rob us blind. If we had to go get $500 out of an ATM and hand it to the pharmacy everyone would have been throwing a fit. Bundle it in with the taxes that get silently pulled from your paycheck before you even get it though? No biggie.
The solution is FBI raids on the headquarters of the carriers, data brokers, and companies that buy/use/resell/share/etc. the data.

Plus the individuals found responsible thrown into prison, and personally bankrupted.

Plus a punitive hit to the stockholders, including clawbacks of past realized gains, to align incentives better with productive society, and not let a corporation be a shield for routine criminal conspiracy.

Working backwards from the desired state, what legislation do we need?
> Interestingly, all these companies are migrating some of their systems to Rust. This suggests that they find the language convincing enough.

I feel most large companies and some smaller ones are interested in trying out Rust, it's trendy. But time will show for which parts the switch was advantageous; and I'm very interested in the findings. The premise of the language is indeed convincing a lot of people. People do however, choose the wrong tool for the wrong job all the time, OP's article in point.
None of this surprises me one bit. I have worked in the health space for several years, and I have personally seen the inner workings of several insurers and the manmade horrors within.

It blows my mind that these multibillion dollar institutions are so poorly managed on the technology/IT front. I think most people will have their health data likely leaked at some point.
It's more useful from a historical context. For the retro community who plays games and creates/uses tools for the hardware of this era, many appreciate having real period correct DOS over FreeDOS, even though the latter is more featureful. IMO FreeDOS is better for a DOS-like OS for modern systems and less useful for retro hardware.
Yeah I saw that quote. I don't get why preference matters? If my preferred medium was spray painting walls, I still don't get to do that because it's destructive.

Im also curious how many people are already sharing their content to everyone else who is hosts videos.

TikTok isn't the only video host. Probably not even the best. The only thing to prefer is their discovery algorithm, and I don't think tiktoks algorithm is speech. I don't think anyone is entitled to a platform.
He is actively developing his new game in parallel to creating the language.

Not to mention smaller projects like 'Braid- anniversary edition'.
The article appears to imply that the direct cost of developing a successful drug is the relevant metric. It isn't; the cost must include the indirect costs of development on drugs that didn't pan out. And the vast majority of drug candidates don't pan out, often in Phase 3 trials where much of the cost has already been sunk.

Put it another way: if making new drugs was so cheap and easy, drug companies would be doing that in competition with each other, and prices would be low as a result of that competition.
Yea, just like road and bridge tolls go away once the project that the toll was supposed to pay for completes... Fat chance!