skysight-inc/HackerNews huggingface dataset:
I've just finished the article and I must say, my feelings are mixed. I'm reading along and it reads like an epic tale where the hero will surely win in the end, it's both mysterious and exciting. I got caught very caught up, wondering what you were going to try next. (Note: It's never Lupus.) But then I would come out of my Dr. House fantasies and realize, this is real. This is your son. And my heart would break for him and your family.

Thank you for sharing, in great detail, the story of your struggle and I hope that in the end it is a story with a wonderful outcome.

Either way, it certainly a story of heroism.

Keep us updated.
Ask HN: What computers can I install Mac OS X Lion on?
I see your point and have added an email signup if you're interested on this page: https://www.foundermeals.com/customers/new

The reason I ask for CC info up front is to further validate the idea. Tons of people are willing to sign up for updates, but many of those wouldn't actually buy. If I'm going to devote many more hours to this product, I need to know:
1. There is some acceptable level of fit with the market.
2. People are actually willing to pay for recipes.

#2 has been a big question for me. Recipes are something you can get online for free, like many other things. But I think there is still room for a premium, convenience product. I've had access to free recipes forever, but I realize that doesn't help me. I need structure. I'm wondering if others are willing to pay for that same structure, but won't know for sure unless I collect CC info.

As for what is included, I am planning on launching with a few options for each component. For example, you could choose 2 breakfast, dinner, and lunch recipes from a pool of 4 breakfast, dinner, and lunch recipes. This should give you enough of a choice, and if you still aren't satisfied - there is a money back guarantee :-)
Do you have proof? I know that on opening Friday we saw it sit at $38.00 and that was obviously MS, but since then I don't see any evidence in the stock price that this has happened since. On the 23rd the stock traded at 31.53 a few times but later in the day traded at 31.52.

I'd love to see MS take a beating for that 100m they got for underwriting this poorly orchestrated IPO, I just haven't been able to see it happening unless there is proof I am unaware of.
From what I've seen, it was hugely overvalued. Maybe $25-$50 billion, with a share price of $28-$32.

Last minute change to $38+ was suicide.
Google made a browser so that Google products wouldn't be hindered by whatever the state of the browser market was. And Google was the Internet for lots of lay users.

Now since Facebook is the Internet for lots of lay users, I suppose they might use the same driving logic?
Show HN - A Facebook-like Timeline for Google News
Not necessarily.

If FB valuations keep slipping, it will put downward pressure on all social startup valuations, which means those companies have less money to throw around.

This is great new for non-social startups. It could mean everything from cheaper rent for office space in SF to a larger pool of available talent to recruit from.
"I’m selling sponsorships for the show directly. Two spots per episode, $2500 per spot."

Wonder how that compares to other podcasts. Strange the network is not selling the spots.
Ah, good to know. I need to lookup the qualifications and revise that. I went with "nutritionist" since it is simple and understood by many. Thank you very much for the heads up!
Nice to meet ya! I've been working on a lisp as well: http://github.com/akkartik/wart#readme
Earthquake, a streaming command line Twitter client.
At this rate these 3 months will feel very long and they will be pretty much "a worry" for those affected.
Quest for the connectome: scientists investigate ways of mapping the brain
Great deal! Sad thing that it's only available in Amazon Kindle format.
hard to believe they can't make the thing much thinner
Sadly, since he's four and a half, "normal" is probably too much to expect.

But, if we can stop the seizures, he might be able to start learning.

He advanced very rapidly during the two month break from seizures that he got from ACTH.

If we stop them soon, there's a good chance he might be able to walk and talk some day.

Regardless of how far he develops, he'll be much happier than he is now.
What's the difference between Clippy and Siri? Maybe it's just that Siri is out of the way until you call her, but Clippy was always there, commenting on what you were doing, judging you.

Maybe Agents would've taken off if you had to press the Windows key or something to summon them.
A false cognate in Python is super(). It does something much different than super in other languages -- calls to super may call some class that is not a parent of the class where the call originates.
Making Yourself Irrelevant – building tools at Twilio to empower coworkers
$5,000 bucks is pretty good income for what is basically a 1-2 hour long "shoot-the-sh*t" phone call between Gruber and one of his buddies.
I'm surprised he doesn't mention why they split as he did in the podcast anyway. Might have cleared it up if he'd just said 'I thought I should get more take, I was lead host, it's a job', we can all relate. Skipping round the topic makes it seem like he doesn't want to come out and say it.
Generally, it is 6 months after the IPO.
Probably based on experience, it wasn't like that initially if I remember correctly.
FB's IPO is based on imaginary numbers. 900 million users? How many actual users. Seems to me that the suits REALLY wanted to make this a $100B company regardless of how much worth it actually had.

There's only so much you can glean out of a social network where the vast majority of the time people are talking about how their day went. I think that some people fundamentally misunderstand the difference between Facebook and Google when it comes to figuring out what ads people want to see.

Let's say I'm on Facebook and I ask my friends for advice on which is the best lead pencil to purchase. They might tell me a few recommendations, and Facebook may even start producing ads based upon that conversation should I choose to revisit it.

But then I want to actually PURCHASE the lead pencil. Where am I going to go to look for that? Google. It will give me price recommendations, and once I've done the search, Google will continue to follow me around with ads tailored to my search.
Gave me a great outline of the key points, didn't waste a lot of time to get to the good stuff ;-)
Which probably doesn't apply while the stuff is still in development.
Thanks for the kind words!

My wife updates his progress regularly here:

http://overcomingmovementdisorder.blogspot.com/

The blog is oddly titled now, since we named it back when he was 8 months old.
A situation I have seen with well-educated novice developers, is that they think of "technical debt" as universally bad. That's not true. It's not even true for actual debt.

Debt is only bad if it's your own long-term debt. One can also use short-term debt as a powerful tool.

For example, it might be simpler for one to write an initial iteration of a program that's badly factored. Then, once you get the program running correctly, refactor it. It's much easier to know you're on the right path if your program runs correctly, and you have verification data-sets or unit tests.

EDIT: Changed one short to long.
The AGPL is still a copyright license, and therefore still only matters if the work is being distributed in some way. If the work isn't being distributed, then copyright permission is not required, and the license is irrelevant.
Lockup doesn't expire until six months after the IPO. Employees and ex-employees have a while to wait until they can begin selling.
I'm not sure about MATE but instructions to install the unofficial packages for Cinnamon on Fedora 16 and Fedora 17 are available [1].

[1] http://forums.fedoraforum.org/showthread.php?t=274611
My guess is that this was the crux of the breakup with 5by5. I have no idea what sponsors pay to be on 5by5 but I would be surprised if Gruber's cut of that was anywhere near $5,000 an episode.

EDIT: Just for the sake of comparison here are the ad rates on daringfireball.net: http://daringfireball.net/feeds/sponsors/
Great Books! Read the Responsive Web Design and Enjoyed!

@sufyanism You can get the free Kindle app from appstore and read it on iPod, iPhone & iPad and Mac as well!
I just saw a documentary about a desalination plant which got closed due to some activists protesting that it was actually letting the salt water flow back into the ocean.

I want them to go bankrupt!
I feel so much more at home! In... 1998.
Just as a useful data point, exome sequencing is now in the sub-$1000 range.[1] There will definitely be a shortage of skilled people able to interpret the data and find mutations like the one mentioned in this article as the sequencing price point continues to drop.

[1] https://www.23andme.com/exome/
I have a dell. Do I need to buy a Mac of some sort? If so, of which sort? Tnx!
Actually it's not quite true! Amazon has quite a few apps so you can actually view these ebooks on your PC, Mac, iPhone, Android, tablets - here is the link for those apps - http://www.amazon.com/gp/feature.html/ref=sv_kstore_1?ie=UTF...

It's not as convenient as PDF, but well, you get navigation, chance to leave notes and change fonts as you like.
6 month lockup no?
Allow user to move webpage content through HTML5
There are only two parties hurt by this:

1. The premiere clients of Goldman Sachs and Morgan Stanley who bought into the lie that FB should trade at >100:1 P/E; and

2. Facebook.

(1) I don't care about. (2) is the interesting one. You'll note that I don't include the employees in the list of injured parties. They're largely in a lockout anyway (I assume?). Whether it opens at $38 and drops to $30 or starts at $20 and climbs to $30 is of little consequence.

Facebook strategically seems concerned with only two companies: Google (disclaimer: I work for Google) and Apple, both of which have established, proven businesses and strategic assets in Internet and mobile going forward.

Facebook is a platform company without a mobile platform in a world becoming increasingly mobile.

Facebook has a lot of cheerleaders, optimists and pundits all backing this idea that the potential of all this data is huge, so much so that I believe they started to believe their own positive press. It's an easy trap to fall into.

But make no mistake: this is bad for Facebook. Sure some investors, Zuck and (maybe?) some employees made a few more dollars but Facebook doesn't need the money and neither do most of the investors. But that's incredibly shortsighted.

Facebook's ability to retain and attract talent and make stock-based acquisitions is in large part determined by the health and outlook of their stock. If they'd IPOed for $20-25 and jumped to $30 then they would have a lot of momentum behind them.

Instead the press is "how low will it go?" What kind of position is that to be in if, say, you're trying to negotiate a $1B+ stock-based acquisition?

Anyway, I'm glad about this drop. Not out of any kind of schadenfreude but because the market is acting... rationally. These P/Es were never justified and instead of not mattering and the stock skyrocketing anyway (which would happen were we in a bubble, which we are not), the stock is seeking a more appropriate level.

This is good for us, the tech industry and the market and the fact that some choice clients of Goldman Sachs and Morgan Stanley got bilked along the way is just gravy as far as I'm concerned.

EDIT: to clarify, I don't really have a position on what the appropriate level is other than $38 is and was too high. It could still well go lower than $30.
Django's CBVs were a mistake
It's 900 million monthly active users. Say what you will about FB but they don't use vanity metrics.
This important lesson can only be detected by parents. People with no children won't ever understand this no matter how hard they try/re-read the articles many times.

Once the infant is out of the womb, everything change instantly without any interference by anyone, anybody, or anything else. The child will change your brain, your mind, your heart, your lifestyle, and your future at that moment of birth. The child IS that BIG.

I cannot say how much I respect parents, even more for those who have children with special needs.

Life is really beautiful isn't it? (^_^).
Is there a Google Docs plugin for this?
Please don't forget their bittorrent offerings, since that protocol was designed for the exact situation where a lot of people want a very big file at the same time.

https://fedoraproject.org/en/get-fedora-all
Looks pretty cool for a Konami code easter egg :)
Employees are typically awarded stock options with a non-zero strike price based on the FMV of the company at the time the options grant. Those options very well could end up worthless.
How do folks generally take an autoincrementing database ID and generate a hash to be used "in public" when trying to avoid revealing obviously serial numbers? I don't think I need something airtight, in fact in one system we just multiplied/divided by a 4 digit prime number. While this worked fine, it seemed a little loose.
rbutr rebuttals can absolutely be rebutted. Any page can be rebutted, so you can follow a whole multi-step debate online.

Is that what you meant?

For example, one link:http://rbutr.com/rbutr/WebsiteServlet?requestType=showLink&#...
where the rebuttal is rebutted: http://rbutr.com/rbutr/WebsiteServlet?requestType=showLinksB...
where the rebuttal is rebutted: http://rbutr.com/rbutr/WebsiteServlet?requestType=showLinksB...
I have a feeling the "business reasons" had to do with non-sponsorship revenue shares. In particular, rev share from t-shirts may have been the last straw for Gruber, especially based on the t-shirt talk on the last 5by5 episode and Dan's blog post regarding t-shirts (http://blog.5by5.tv/2012/5/22/t-shirt-status-update) where he explicitly mentions that hosts will get 50% of the profits from their show's shirts.
Those same students and programmers should realize that yours is just one opinion among many. Your advice leans toward the "fungible cogs" school, where the capital crime is to expect others to learn something they don't already know.

That's still a widely held view, and maybe even a majority, but probably not on HN. (see pg's Beating the Averages essay:
http://www.paulgraham.com/avg.html)
Or Ka-Ping Yee's crit.org back in the 90s.
I had a lot more fun playing with this Clippy than I thought I would. I remember HATING Clippy and now I'm questioning why I did.

The only conclusion I can make is that it wasn't the actual character and its animations that I hated. They are, if I'm being honest with myself, kind of cute and endearing. The reason I hated Clippy was that it was condescending.

"I see you're trying to write a letter. Would you like me to help you with that?"

Hindsight is 20/20, but Microsoft should have realized there's no way to phrase that and not insult the intelligence of 90% of your users.

Interestingly, I see an analogy here with today's GPS software. No matter how nice they make the voice sound, they never fail to sound condescending when you veer from the pre-calculated route. I love MotionX GPS Drive for the iPhone (other than the fact that it crashes every time I go to another app), but the default voice manages to make me physically angry every time she says "Rerouting". You can almost hear the disappointing frown on her face, as if she's saying "sigh I guess I'm going to have to plot a new course since you're obviously not smart enough to stay on the one I made for you."

How hard would it be to make a GPS system that just assumed I might want to get gas or stop for a bite to eat if I took an unplanned exit off an interstate with hundreds of miles to go on my journey?

I think Clippy and rude nav systems are different manifestations of the same problem. It's a kind of "uncanny valley of human-computer interaction", although here the revulsion is not triggered by looks or movement but by BEHAVIOR. It's behavior that is almost, but not quite, human. Specifically, I think it's triggered when a computer system takes a tone of intellectual superiority over its user.

Because most of us know that our technology is nowhere near the level of intelligence needed to actually be wiser than we are, we feel the same kind of indignation and resentment at the posturing of the system as we do when a small child insists that we don't know what we're talking about while answering their question about why the sky is blue.
FB IPO is bad for the inflated startup world around the FB ecosystem. All stuff "social" and "connected". It's hopefully good for everyone else who is bringing some value, but was turned down/undervalued, because they're not social enough.
It is all manual I am afraid. We are reaching out to Skeptic communities right now in an effort to get the ball rolling and get as many rebuttals added as possible. We're getting amazingly positive support from the Reddit skeptical community (which is where this post came from), and I will be at the Amazing Meeting in July, talking to skeptic community leaders from all over the world.

But of course, everyone and anyone can add rebuttals, so please, feel free to add any whenever you happen across one :)
I think the craziest part about this is that the snake attaches itself to the outside of your beating heart, and then does it stuff. A kind of elegant, but also creepy solution to operating on a beating heart. I remember reading about the Raven surgical robot (not a snake, or really a raven... but still a surgical robot) that had a module for compensating for the beating heart under development. Like, they would try to move the robot arms in sync with the heart to remove relative motion. NUTS!
Greatness is achieved when you can not take anything away anymore and you are only left with the important things.
I have a shelf dedicated to my MongoDB mugs, and there's still some room for them to grow.
While this is anecdotal, some ibanking friends told me that alot of the traditional wall street banks 'boycotted' google for going w/ a smaller player who did a non-traditional format (auctions) that threatened their business model and that resulted in lower demand (and lower price) for their shares at IPO than would have otherwise been the case.
copyright lawyer invasion in 3...2...
Dude, as a recently minted father, I can't begin to grasp what you guys are going through. I just want to wish you the best of lucks with this.

On a completely unrelated - and irrelevant - note, I find your writings fascinating.
It sounds like they've let their ego overtake their product.
The game is not as simple as maximizing the value of just the shares being sold on day 1. Post-IPO, a company's shareholders are largely the same as pre-IPO... the value they achieve for their shares in will be determined over a much longer time frame. Reputation / performance matters.
The gyro-stabilized, two-wheeled future of transportation is the bicycle, people. Seriously.

If you're really into it, you can throw an electric assist motor on.
I was hoping someone would make this, so I didn't have to. I have a feeling we'll see this turn up a lot sometime around 4/1/13.
No, it isn't!
+1 (more subscriber). wish i had discovered this a while ago.. was piecing through the archives after signing-up just now, already stumbled upon some great posts i missed.
> I think you are doing students and young programmers a disservice by implying that there is one "best" solution here, and that you know it.

I read their requirements in the blog post. They need fast access to SVN and Git internals to store off metadata. Based on that it's really not hard to determine what to use to solve this problem. There may not be one exact right answer (in fact, I suggested two), but there is a direction that makes sense and one that does not.

The real disservice to those coming up in this industry is reading blog post after blog post on Hacker News with people looking for "excuses" to use random languages they're interested in playing with. The answer to most of these problems is to use something really boring and straightforward, like C, C++ or Java. I guess I've worked too many places where legacy code becomes a huge burden because one guy wants to play around with X one time. The funny thing is, I see these same guys go onto the next place and do it there.
First thoughts reading up on this pretty cool bit of detective work: Since this is a deficiency in production of Pngase F, I'm not sure a simple injection of Pngase F is going to work. I'd guess you'd need to target Pngase F into the ER to kick start the proper clean-up process, and the human form (http://www.uniprot.org/uniprot/Q96IV0) is different to the recombinant form that you can get synthesised (http://www.uniprot.org/uniprot/P21163). I'm not really sure how native Pngase-F is regulated!

That said - I'm about to start work on very similar work now (also in the area of glycobiology). With dirt cheap exome sequencing, we're going to get a whole bunch of really interesting leads from the data. This means that the follow-up research into the mechanism behind the action of the gene can be more likely to yield results.

Right now, I see the bottle neck in this whole process being the actual experimental analysis of these mutations. Once we solve how to scale up this hard work successfully, we can start looking at curing these incredibly rare diseases.
Sorry, not worth it at all. Years 1-10 - you will loose all your time - cleaning diapers, making the child eat, making it study, teaching it values - waking up at night - and doing a lot of things for it. Yes you'll see it learn, smile, grow up and you're genetically conditioned to like it. But you will not be able to play your games, go to your parties - read book or contemplate on life, or code without expecting interruptions.

Years 11-20 - manage the child's other needs - worry about getting into a good school/college, making sure there is no bad company, and making sure no bad mistakes are made which can be made very difficult due to teenage defiance to old values etc.

Years 21+ - child will leave and stay separately - you should more or less start becoming free once again. That is if you do not have a second child!
How can you say the P/E isn't justified when Facebook isn't monetizing +60% of their impressions (mobile)?
Oh wait...Official Dates and Official WWDC 2012 iOS App Announced
After a minute of thought, I realized that maybe he's being classy now because he realizes that the podcast's audience is what allows him to command $5000/episode in sponsorships.

When the breakup first happened, he might have taken the listeners for granted, which explains why instead of posting today's post a week or so ago, he chose to post some oblique passive aggressive entries instead.

Once people started publicly announcing their "unsubscribes" in droves and leaving negative comments on iTunes, Gruber himself decided to sing a different tune.
It is only 'worth it' because your genes needs you to protect the next generation.

Rationally there is no point in having children at all.

And speaking statistically, research shows that parents are no more happy than are those who are not parents.
Siri tries very hard to be a true "agent"; that is, the makers of the technology strived to make Siri something that would perform tasks on your behalf and at your command.

Clippy was also intended to be an "Agent", but it failed spectacularly at it because:

1. It tried to help you when you didn't want help, like an annoying intern who won't leave you alone.

2. When you actually wanted it to help you, it was invariably unable to perform the tasks you wanted.
I've wanted this for a long time! I can't wait to code this, as a joke, into one of my sites and have clippy popup on a few key words.
Facebook’s IPO shows the playing field is permanently tilted