skysight-inc/HackerNews huggingface dataset:
ImageJ has roots (NIH Image) that predate Photoshop.
Kolmogorov complexity is a lovely subject and one of the more influential ones in my life.

THE book https://link.springer.com/book/10.1007/978-0-387-49820-1 is absolutely a thing to read. It was for me 30 years ago and it aged well.
Fullmetal Alchemist isn't real life. You don't have to account for every microgram of material along the way for a drug to be useful and safe.
Where I'm from we have holes in the top corners of the cover. Just put your arms in there, grab the duvet and pull it in, shake it a bit, done (additionally you might need to fix the bottom corners and shake again). I was surprised when I went to other countries where you have to fiddle with only a bottom opening.
Soylent Green was set in 2022/2023 https://en.wikipedia.org/wiki/Soylent_Green?useskin=vector
Absolutely they should.
Near disaster on Airbus due to subtle software issue [video]
>Housing is universally messed up everywhere in Western world, no matter salaries.

Not to the same scale though. IN Europe and especially Canada housing is way more expensive to buy than in the US relative to local wages. Americans forget how good the4y have it.
This near accident was due to a fiendish unanticipated set of circumstances interacting with software logic intended to improve safety.
That is exactly what I want us to do :)
Except that that’s not an actual natural law. In the same way that sometimes bad things happen to good people for no reason and with no compensation whatsoever, sometimes good things happen to people as well, whether they “deserve” it or not.

Other than that, what’s the problem with a weight loss drug? That it’s “unnatural” or “cheating nature”? The weight gain and the corresponding lifestyle and nutrition that often cause it aren’t exactly nature-given either.
What it does is this: RSA_public_decrypt verifies a signature on the client's (I think) host key by a fixed Ed448 key, and then if it verifies, passes the payload to system().

If you send a request to SSH to associate (agree on a key for private communications), signed by a specific private key, it will send the rest of the request to the "system" call in libc, which will execute it in bash.

So this is quite literally a "shellcode". Except, you know, it's on your system.
Agreed on a moral level, and it's true that describing this as simply "vulnerable code" doesn't capture the clear malicious intent. I'm just struggling to find a specific crime. CFAA requires unauthorized access to occur, but the attacker was authorized to publish changes to xz. Code is speech. It was distributed with a "no warranty" clause in the license.
Thanks for responding. My experience with tracing GC at scale is exclusively in the realm of .Net, and RC exclusively with C++ smart pointers. That matches your “sophisticated vs crude” contrast.

The experience with .Net is that GC impact was difficult to profile and correct, and also “lumpy”, although that may have been before GC tuning. GC would dominate performance profiling in heavy async code, but these days can be corrected by value tasks and other zero alloc methods.

For C++ style ref counting, the impact was a continuous % load and simple to profile (and therefore improve). Although here, the ref counting needed to be stripped from the hot paths.

The biggest issue I’ve hit between the two modes though, is how they behave when hitting memory limits. Tracing GC appears to have an order of magnitude perf hit when memory becomes scarce, while ref counting does not suffer in this way. This is enough for me to personally dislike tracing GC, as that failure state is particularly problematic.
Disguise utility boxes, cell towers, etc?

…If the sheet flexes so you bounce right off it, the cyclist, bird, and aircraft crashes in such a case might not be that bad, I guess…

Wildlife photography, field science? You only need to cut a hole in it big enough for a couple sensor apertures.
https://www.extrapetite.com/2021/03/how-to-put-duvet-cover-b... Might make a bit more sense, but I’m still trying to follow it myself. I’ll have to try it to get it, I think.
There's not a single drug company on the market that stops charging a high price for a drug as soon its covered its research expenditure.
> "Sorry Dave, you're not allowed to open a terminal."

No 9000 computer has ever made a mistake or distorted information.
They almost certainly didn’t cure obesity. Food manufacturers are already scrambling to figure out how to make foods even more compelling and less satiating.

Regression to the mean, and our grocery selection will suffer further.
The crews bracing themselves for a rise in electric car fires
> Unionized workers are the only real backstop against corporate interests.

The problem is just like you said, though: Wealth inequality weakens collective bargaining.

A union only holds power by being able to force a stoppage of work, but workers can only afford to stop work if they are rich. Without the arrow of wealth inequality reversing, unions will continue to falter anywhere the workers are poor.

That's just basic economics. However, figuring out how to reverse said arrow is extremely complex economics. If we knew how, we'd have done it already.
Was it how topology was invented?
I just hold the duvet by the two front corners, shove it inside the cover and find the edges. Hold the edges from the outside of the cover, shake. Takes 30 seconds.

We also change it weekly, sleeping in the same covers for a month sounds disgusting.
Show HN: How I Started Selling Physical Art Made in Inkscape
It's false equivalence. The scale, targeting and intent of what Russia is doing versus some US agency are not comparable.
To be fair, some people are saying that about vaccines or antibiotics.

Fortunately they don’t regulate access to either for most people in the world.
Exactly this. And it’s because the US consumer is paying for the R&D on drugs for the rest of the world. We could balance this out a bit by passing a law that says the retail cost of a drug in the US can’t be any higher than the median of the EU + Canada (or something approximating the set of developed economies).
That's true, but many of these maintainers work a day job on top of doing the open source work precisely because the open source work doesn't pay the bills. If they could get back 40 hours of their time I think many would appreciate it
Well, he did have Alzheimer’s, a degenerative brain disease that affects memory. And we’re supposed to believe that he had no symptoms of until January 21, 1989.

As a person that had a grandmother and aunt that developed it, that’s… mighty suspicious.
There is an awful lot of sympathy for the drug company in this thread. You are correct, research and approval is expensive. But at some point there is a limit.

Things like insulin are long paid off, and the pricing there has generated controversy. People have been charged $1000 a month for it [1].

What’s fair? They are screaming out to be regulated when they behave so badly, and that’s what’s happened with insulin.

[1] https://www.thelancet.com/journals/landia/article/PIIS2213-8...
Isn't everything healthcare-related much more expensive in the US?
Now available on GitHub & VSCode Extension. AI searching assistant for developer that semantic search and talk to codebase & Notion workspace.
Doesn't the modern variation break for programs with lossless encoding/decoding? At least, for sufficiently long sequences? A Huffman/byte-pair encoding would shred any trillion-bit+ sequence, for instance. But I intuitively expect many random trillion-bit sequences exist.
Hey. How much would you estimate a networking for O&I SuperPOD will cost?
I don't see health insurance making profit being unreasonable. That is key reason why anyone would run an insurance scheme. Now the USA model is entirely wrong. But fundamentally, to offer insurance you must get something out of it.
This is the way. I also use this method and change weekly. It’s pretty efficient, especially for larger duvets.
Best decision I ever made was to skip the duvets and buy a polar fleece blanket for $30. Not to hot, not to cold, machine washable and $30.
I'm offended by the notion that any woman depicted nude is somehow pornographic. I'm also offended that people say it objectifies women- as if they lack agency.
If I remember correctly that cost is also only the price of developing a successful drug

Several drug developments are halted before they reach market. Novo for instance lost a lot of money on their bet to develop inhalable insulin 15 years ago

That cost also has to be recouped when finally hitting the jackpot
Pip and similar are their own can of worms yeah. They trade convinience for an almost complete lack of oversight.

But in this case we are talking about people (distro packagers) manually downloading the source and building it which is not quite the same thing.
It doesn't. That was one of our mistakes and action items to fix.

The original proxy was stood up quickly when it was first discovered IPv6 was broken and the people standing up the proxy didn't know at the time how ACME worked.

We'll be changing it to just a TCP proxy.
As opposed to? The buck has to stop at a human somewhere
Goes for any software that can be copied
Society contributed to that research in the form of education, academia, infrastructure, ...
No one else misses Picasa?
you also need to cover the cost of the 100 drugs that failed at various stages of the pipeline.

Not saying that it's not a screwed up industry, but stories like these distort the problem as well
Is that your experience? I see people loosing the empathy with colleagues, colleagues are just a handle on slack, not committing in the level they should, not attending meetings. Meetings where people are just looking their mobiles, don't turn it on their cameras and don't participate at all at meetings.. It happens a lot and with some people the whole social aspect deteriorates pretty fast. In the office there is a dynamic that for some people is vital, the social aspect... i.e people tend to be much less rude and open to compromise face to face than just online..
> Unionized workers are the only real backstop against corporate interests.

This isn't true, and is often undesirable since unions serve workers, not customers.

Competition is what keeps corporations in check, and is most likely to benefit everyone. Of course unions are important to workers and also have their part to play.
There was a recent story right here on HN that contradicts that narrative.

"Big Pharma spends billions more on executives and stockholders than on R&D"
https://news.ycombinator.com/item?id=39405547
I mean facts are facts. Emad is gone, the company has lost people (researchers and executives), and they have not announced a blockbuster AI funding round.
WTF?!? People don't change bedsheet every week?!
Still confused. What is contradictory about a simple program computing a more complex program? Randomly generating a more complex program does not make the complex program reducible to a random string generator.
Interesting that this is referred to as Japanese shirt folding. This is how I learned to do it decades ago, and there was no Japanese attribution at the time. I wonder if it is claimed (by whom?) to have been invented in Japan, or if it's just because the video is in Japanese.
I've found nomacs to be a good alternative:

https://nomacs.org/

It hits the sweet spot when it comes to clipboard functionality -- You can either copy the image itself, or copy its path on the filesystem. Most image viewers only support one of these commands.
https://archive.ph/nqYtP
Seems to be going better in India:

https://www.youtube.com/watch?v=adTsC7RPlUs
I would expect a nation state to have better sock puppet accounts though.
In the UK, at least, unauthorised access to computer material under section 1 of the Computer Misuse Act 1990 - and I would also assume that it would also fall foul of sections 2 ("Unauthorised access with intent to commit or facilitate commission of further offences") and 3A ("Making, supplying or obtaining articles for use in offence under section 1, 3 or 3ZA") as well.

Though proving jurisdiction would be tricky...
Ive done this a few times. Depending on the startup (size, domain, technical complexity, resources) it could just a coder with a fancy title. Now nothing wrong with that if you are getting to build freely, solving hard/interesting problems or working on problems that somebody is willing to pay tangibly for or you are trying to just get your startup creds up for your next play.

But I have found often startup CEOs look for CTOs for a few tactical and myopic reasons. They cannot code (or worse cannot design beyond copy-pasta from stackoverflow) or just to bolster their "look we have a faang-er as CTO" creds. Just as often the CEO has very little business or product sense (not to mention any leadership) but just needs a coder to build out their ideas (usually half baked ones in a very reactive fashion). Here you will also find that there is a new direction each week based on what a lead told them in passing.

Worst of all you will have very little resources (are you the sole coder/CTO?) but will be blamed for all the wrong choices (dont worry about writing tests - we dont have time ===> why are things breaking?).

The pendulum in this case is not a bad choice. Typically after you are burnt by one startup it doesnt meant all startups are bad. Just that you could use that big-co IC role as a charging station. Or if you actually like management (and there are lots of reason to) you could always switch to management in a big co and then go back to a startup more worthy of you. Now obviously you are the mercy of the hiring committee/team/market so a better story for why the switch definitely helps.
> The math of the lzma algorithm doesn't change. The library was "done" and that's ok.

Playing devil's advocate: the math doesn't change, but the environment around it does. Just off the top of my head, we have: the 32-bit to 64-bit transition, the removal of pre-C89 support (https://fedoraproject.org/wiki/Changes/PortingToModernC) which requires an autotools update, the periodic tightening of undefined behaviors, new architectures like RISC-V, the increasing amount of cores and a slowdown in the increase of per-core speed, the periodic release of new and exciting vector instructions, and exotic security features like CHERI which require more care with things like pointer provenance.
Also check the corresponding blogpost: https://blog.hartwork.org/posts/expat-2-6-2-released/
My 91 year old mother can't use her cellphone well, the user interface of even the simplest flip phone confounds her. She forgets to charge it, loses the charger, etc.

I don't know what she'd do without a landline. It's already become much less reliable because the NY Telephone company doesn't care about the old copper lines so we switched to sevice over FIOS. If the battery in the main unit fails--and she can't hear the beep that warns that the backup battery needs to be replaced--her phone goes dead.
The target market for Ozempic is tens of millions of people taking it every week.

The blindness thing has a worldwide demand cap of about 40 doses per year - it's a single dose for life in each eye).

Are you equally surprised when a one-off bespoke PCB costs more than a stock RaspPi?
Is it illegal to distribute malware? I see security researchers doing it all the time for analysis purposes.
https://archive.md/14sJa
By the same logic, all software should be free, because the cost of manufacturing the bits is zero! (Yes, I'm very aware of rms and the FSF.)
Sums up the ban: https://i.redd.it/leo33bwem9rc1.jpeg
Another reason to adopt OpenBSD style pledge/unveil in Linux.
Insulin isn't a single product.

If you're not distinguishing between insulin extracted from a horse circa 1922 and a modern synthetic analog, well that's just not being honest.

There's good arguments that the modern synthetic analogs are overpriced, but that's a more subtle argument.
Pretty sure R290 is flammable and I believe being used more and more
I'd say that the beginning of the year ends at the end of Q1, if not earlier.
I’ve always wondered that too. A lot of people will claim that “it’s their right” to not be recognized by surveillance and that’s why they use those covers, but seems a lot more likely that they don’t want take responsibility if they get in an accident that they can slip out of without being identified.
They are the exact same active pharmaceutical ingredient (semaglutide), only differ in dosage and the design of the pen used to inject them. Ozempic is a multi use pen while Wegovy comes in fixed dosage single use pens that max out higher than Ozempic's highest dosage.

Glycemic control wouldn't be any different between the two at the same dosage but yes, people should really be seeking out Wegovy or Zepbound (tirzepatide) since those actually have a chance of being approved by their insurance for weight loss based on their FDA indication vs Ozempic or Mounjaro.
Falcon – The minimal, fast and secure web framework for Python
This is ridiculously dependent on the current state of LLMs. The tricks necessary today are unlike to be relevant in 1-2 years.

Anyway, calling those tricks "engineering" is as ridiculous ad calling garbage collectors "sanitation engineers". It isn't engineering and there is no discipline.
The paper models a competitive (cheaper) and conservative (more expensive) pricing. The conservative model assumes a 50% profit for Ozempic (the competitive model assumes 10%). These are margins that cannot realistically sustain drug development in the current western regulatory regime.

At the same time, its quite clear that the cost of drugs, particularly in the US is out of control.

In that sense, focusing on the fact that a company that received the technical data package and plant for manufacturing Ozempic for free could then indefinitely sell Ozempic for $5 a month is a red herring, and not likely to lead to any fruitful change. The price differential between US pricing and say... UK pricing ($350 a month for injectable Ozempic vs ~$80 a month) is enough to hammer in on.

On a side note, what I found interesting is that while the article says a injectable Ozempic can cost ~1k a year, the actual study marks it at more like $350 a month.
I agree with your disagreement. As a case in point, Nim has packed bitfields but various choices in automatic memory management. As a concrete example, a spell-check custom-data store uses them here: https://github.com/c-blake/suggest/blob/04e313f8f8d3adf4cb55... (there the memory is in a memory mapped file and so that code has to manage the space itself.. so, maybe not the perfect example).

But I also agree there tends to be a correlation in PLang design in avoiding both low-level memory layout and in manual memory management. But it's just a tendency, not fundamental.
Steel can load cdylibs (this is used for the integrated terminal POC plugin I think) so Rust plugins are already possible with that PR.
Getting a job at a hedge fund is not particularly noteworthy. Being really good at it, however, is rare and those people don’t simply leave, as you’re earning the equivalent of a successful startup exit every year.

Someone leaving a hedge fund while still early in their career is a strong negative signal. e.g. SBF and Caroline both from Jane Street.
It doesn't matter how fast you flip coins, in the end it'll be 50/50 anyway and you'd still get the same success (price of failure wouldn't matter, it'll always be the same value in the end).
I once zipped my girlfriend up inside a cover while she was doing this, it was quite funny.
That is fascinating. Just asked my wife, who's from another continent, she's as flabbergasted as me.
The only other tech CEO I can think of who has a Hedge Fund background is Jeff Bezos; are there enough other examples to start stereotyping?
> It seems I have worked with more human idiots than you.

This is completely unnecessary.
SSB requires more sophisticated frontend than FM because the channel is smaller and reuqires less noise. There are HF radios that use a simple signal generator, but then need a complicated frontend to be able to received anything. The cheap SDR HF radios are $500 when SDR VHF handhelds are cheap like this one.
Chaotic Progress
How vigorous competition among public political parties and private for-profit companies has promoted progress by balancing the personal interests of new entrants and incumbent elites
That limit is the length of a patent (plus/minus some factors like extensions and time to market). That's been the deal ever since the FDA was a thing. It's nothing new.

My understanding is that the controversy is over a newer type of fast acting insulin that's not yet generic. In general insulin is really cheap, but the really nice new stuff makes life a lot easier for diabetics so everyone wants it.
Regulating drug pricing is what has started to happen. And I’ll bet they don’t like that.

A single payer system would at least change the negotiating power that big pharma has - even in a small market, drug companies hate dealing with a single buying. Here in New Zealand the point even made it into the TPP agreement negotiations. The US wanting our (deeply imperfect) healthcare system to be a bit more like the US one is rather grim.
`pip install` does do exactly the same thing: it downloads and executes code from a tarball uploaded to PyPi by its maintainer. There's no verification process that ensures that tarball matches what's in the git repository.
No, it is not illegal to distribute malware by itself, but it is illegal to trick people into installing malware. The latter was the goal of the XZ contributor.
When you hit memory limits, .NETs GC implementation would perform much more frequent, invasive and aggressive collections, including LOH compaction to reduce memory watermark which leads to greater GC pauses, though this is rarely seen in such a bad way on modern versions with e.g. SRV GC.

The most scaling way to address this is usually to just allocate less and use valuetasks with pooling where applicable (frequent asynchronous yields), I'm certain if you built a .NET 8 based solution you would see user-written code dominate heap allocations profile, as most hot internal paths of async utilize said state machine box pooling+ValueTask<T>[0] and may be entirely allocation-free.

[0] Example: https://github.com/dotnet/runtime/blob/cc7bf831f02cad241547e...
Is this a Silicon Valley thing? I've certainly never thought of a coffee shop this way. I sung along to a bad 90s rock cover at one once with about 30 other people. It was a great time.
It’s not quite the same, although I’m assuming that no one needs Adobe to stay alive.
I have met people like that. Sorry.
It was the largest bomb ever until then, yes. But to equate a fission bomb to a fusion bomb is a disservice. We’re talking multiple orders of magnitude more powerful.

If you want to know the difference, I suggest nukemap. To put it in perspective, we’re talking about destroying lower manhattan with the Fat Man, versus incinerating all five boroughs and shattering windows in White Plains, NY. I’m not talking about dick waving stunt like the Tsar Bomba, I’m talking about deployed weapons.
I think it could be useful for shorter people who can't hold it up high enough. I just hold it up and shake it, though.