skysight-inc/HackerNews huggingface dataset:
Health systems in other (comparable) countries, where drug prices are centrally negotiated or outright set by government committees are vastly more efficient in terms of cost and generally produce better results in terms of health outcomes.

I.e. in my native Germany, health expenditure per capita is 2/3 of what it is in the U.S. if faced with a life-threatening illness, I would vastly prefer to be in Germany than in the U.S. (with the possible exception of being super-rich and being able to buy top-of-the-line health care).
@low_tech_love can you help us to remove the ones which are not generated by Sora?
We linked each item to the tweets so the visitors also can test themselves. We will add more videos as Sam Altman publishes more
"Chemical cocktail could restore sight by regenerating optic nerves" (2024) https://www.newscientist.com/article/2416821-chemical-cockta...
It’s just state.
A big state, but just state.
VNM applied in the realm of ethics is definitionally utilitarian.
At a large insurance company I worked for, management set a target of 80% test coverage across our entire codebase.
So people started writing stupid unit tests for getters and setters in Java DTOs to reach the goal. Of course devs also weren't allowed to change the coverage measuring rules in Sonar.

As a young dev, it taught me that focusing only on KPIs can sometimes drive behaviors that don't align with the intended goals.
A few well-thought out E2E test scenarios would probably have had a better impact on the software quality.
It's illuminating to listen to how a Russian saw that interview:

https://www.youtube.com/watch?v=bQ-iXSPZi_Q
This is analogous to how much medical research is done. Unless you want to go the literal Nazi method of inducing illness or incapacity and then testing remedies, this is sort of the best we have. Final stage medical research involves humans to test on. Preferably voluntarily, and preferably when they require the treatment through actual misfortune
.
People keep saying this and I don’t buy it. Kids arent going to learn the best by staring at a computer screen eight hours a day.

If this happens it’ll be because of reduced education funding, not efficiency.
What I've seen the most is rolling back the deployment (if any) and writing a new commit with the fix.
This is the problem(with Apple); this device, like iOS devices, is fenced off, so you cannot run vscode etc if you don’t connect a MacBook. For this device it’s actually worse than an iPad to disallow that: it’s 4x as expensive as a MacBook Air here but I cannot run most apps I want on it while that would make me buy one today. I don’t want another iPad (which I bought because it’s nice and small and great battery, but if I cannot code on it normally, what’s the point).
"Vision rescue via chemically engineered endogenous retinal ganglion cells" (2024)
https://www.biorxiv.org/content/10.1101/2023.12.27.572921v1 :

> Loss of retinal ganglion cells (RGCs) is the final common end point for many optic neuropathies, ultimately leading to irreversible vision loss. Endogenous RGC regeneration from Müller cells presents a promising approach to treat these diseases, but mammalian retinas lack regenerative capacity. Here, we report a small molecule cocktail that causes endogenous Müller cell proliferation, migration, and specification to newly generated chemically induced RGCs (CiRGCs) in NMDA injured mice retina. Notably, regenerated CiRGCs extend axons towards optic nerve, and rescue vision post-NMDA treatment. Moreover, we successfully reprogrammed human primary Müller glia and fibroblasts into CiRGCs using this chemical-only approach, as evidenced by RGC-specific gene expression and chromatin signature. Additionally, we show that interaction between SOX4 and NF-kB determine CiRGC fate from Müller cells. We anticipate endogenous CiRGCs would have therapeutic potential in rescuing vision for optic nerve diseases.
Yeah, but that means you can really live Hyrum's Law.
Let’s assume for a moment that AIs turn up as you say, and that there is nothing nefarious. That outcome will need a lot of foresight and democratic regulation, because market forces will want AIs to exploit people. But, let’s assume we find a political system that is smarter than the people wanting to use AIs for bad ends. So, the world would look very much like the world now, where you earn money proportionally to how difficult is to replace you. There probably will be a set of skills incredibly difficult to get that will earn you enough money to live a comfortable life. And that’s the problem. Even now, lots of people never attain those skills, and they end up working at a factory or at an Amazon fulfillment center. If we don’t fix things somehow, how much worse will it be in the age of AI?
Why “he”?
I don't get, most who could get trapped by signing/donating to the new guy could already be via donating/signing for Navalny. Years passed and nothing
in magit you can also select lines you want to commit. It's there in the article as well
Wrong - I am actually Tatar with Ukrainian passport, but it’s a long story…

Just read the article you quoted. Are you referring to 1944? We can go all the way down to Crimean war if you want. Your original statement made an impression that you were referring to recent events?
What is winning and what is losing? Yeah there are actions that persist our genetics but there's no rule saying that's what needs to happen, just that it's something that happens.

If you widen out to society, yeah, there are other people who will come after us, maybe we can have purpose in helping those people to survive even if they're not our kids. Humans evolved as a collective, there are parts of our DNA that exist to help the group even if it means we ourselves don't have kids. Evolution is a much more complicated thing than just specifying exactly what genes -you- pass on.
I think everyone here knows how big pharma works (well, doesn’t ‘work’ as such) however this needs to get into the press a lot more for the public to see.
Update on apps distributed in the European Union
> Big Pharma has a very powerful lobbying arm that is against Medicare negotiating down prices.

I particularly liked how all the Congresspeople involved in writing that the government couldn't negotiate drug prices into Medicare Part D immediately retired and went to work for the drug industry.
Yeah it’s more useful to think of unvalidated state and validated state. Use different types if you can.

What I don’t care about is if the state is from a prop, a value inside a DOM object, a global…

If I have to know where the state comes from, the code is smelly
Problem with valuations is that there has to be a buyer for that 7-15x. There is a lot of businesses that are not sellable because “owner is the business” and then comparing to normal job makes sense, because that is other realistic alternative.
Did they implement Interledger Protocol (ILP) for their traditional or digital asset ledger?
https://interledger.org/developers/rfcs/interledger-protocol...
The production costs of creating 3D content that is actually making use of the extra dimension will be cost prohibitive for lots of types of content where 2d is used today. I really wouldn't care much for lots of YouTube content I watch being provided in 3d, half of it I already just listen to. As an example, look at how much more detail needs to be added to a room in a VR game versus a standard 3D game - since you have more freedom to poke around and look at things from more angles, stick your head in things, the expected level of detail is much higher. Just adding VR to existing games can make for a good experience, but VR native content will be more expensive to produce.
Nothing in that article actually addresses the point. The average life expectancy where I live is currently 83+, despite notably higher fatal injury rates.

In terms of actual medical outcomes -- survival rates for cancer, cardiovascular events, trauma medicine, etc -- the UK is quite a bit worse than the US. The only countries that stand out as consistently competing on medical outcomes are France and Switzerland.
Same question. I thought that solves the privacy problem.
That assumption would have to be proven first.
SaaS sales / sales engineers. Much easier to get there compared to SWE as well.
I think a prerequisite to that is figuring out how to get them to not spit out complete bullshit consistently anyways.
I think we're socially primed for it right now - at-least here in the US. Unlike other cultures where you're living with a large family or extended family or your parents, etc, life in the US is getting to be more and more solitary (IRL, people are still forming social connections online) for young people. That makes it very easy to adopt this type of tech. In other cultures wearing it around the house will just make you look like a weirdo.
Interesting. I have a Studio Display and it just feels like a huge compromise.

There are only two 5K displays on the market that can render macOS at Retina resolution on a 27" panel: this one and the LG Ultrafine, which isn't that much cheaper. My last monitor was a 27" LG QD-OLED 144Hz 4K display. I LOVED that display, but text wasn't sharp because of the Retina resolution problem.

I also have a semi-professional webcam setup and external speakers, so those being built-in does nothing for me.

I just want macOS to support variable scaling like Windows has for, what, 15 years at least?
* I suspect the social value of school will become much more apparent soon.*

School is not just about the academic knowledge you gain. Plus, I'd imagine pairing a personalized tutor with an effective human teacher would only accelerate learning faster.
True of any metric when it becomes the goal in itself.
Chaotic behaviour is deterministic
I keep hoping for an expanse experience. Where computing is truly connected (standards and fast wireless transfers). Apple ecosystem is moving towards this but they are so closed it feels more like autobus than bicycle for the mind. Linux is still not an option on the phone form factor. And the hardware are still very opaque.
Show HN: I built an alternative to product tours
Hey HN!
We’ve built a tool that dynamically adjusts the complexity of software interfaces based on a user's interaction with it.

It works by hiding non-essential/advanced UI elements for new users, reducing cognitive load and guiding them to their "aha moment" more efficiently. We refer to this as „simple mode“.

Non-essential features are progressively revealed when the user is ready to use them, and we’ve also added an option for users to manually switch „simple mode“ off.

Every Feature in vykee consists of Elements. Elements can be selected via UI picker or via code by adding the vykee attribute.

Our analytics tool allows you to easily measure the usage of Features and Elements over time. You can identify the ones that are (a) not used or (b) used a few times in the beginning but not again. Those non-essential Features can be hidden by applying conditions for revealing them.

As we’re still very early, I’d love to get your feedback on the tool and thoughts re simplifying complex software more broadly.
>is fenced off, so you cannot run vscode

No, the only reason you can't run vscode is that no one has put in the effort to port it. It's a problem of financial incentives and not a problem of "fences."
Love the real title bars and buttons. SGI 4dwm had one of the best of this style.

But I happen to like the taskbar from 95+.
One of my favorite mathematical tangents involves a theorem of Littlewood.

The prime number theorem states that the prime counting function $\pi(x)$ is well approximated by the integral $\int_0^x \frac{dt} {\log t},$ which is a function that's become named $\mathrm{li}(x).$ Littlewood proved that the sign of $\pi(x) - \li(x)$ changes infinitely often, but his proof didn't produce a specific value where such a sign change occurs.

In 1933, one of Littlewood's students showed that, assuming the Riemann hypothesis, at least one sign change occurs below the number $e^e^e^79$, which is approximately $10^10^10^34.$ In 1955, he was able to show unconditionally that such a sign change occurs below the number $e^e^e^e^7.705$, which is approximately $10^10^10^964$.

Both of those numbers absolutely dwarf the estimated number of elementary particles in the observable universe, so it's utterly impossible to either compute or write them down, even if you used the entire universe as your computer or your writing surface.

https://en.wikipedia.org/wiki/Skewes%27s_number

That upper bound has since been lowered in 1999 to 1.38922 * 10^316 here: https://www.ams.org/journals/mcom/2000-69-231/S0025-5718-99-...

I imagine it there might have been a bit more progress in the last 25 years, but I have no idea if it's possible to actually write down all the digits of the current best upper bound.
As a first take: this is incredible, magical. Even if subtle problems make this iteration impractical for sustained use, it is clearly a bellwether for things to come.
I used to get angry at my Norwegian teacher when we were forced to analyze poems, because I like writing poems but never once felt compelled to insert the kind of forced symbolism he kept insisting we rip apart and shred and murder poetry to identify.

Because it wasn't what I wrote or read poems for.

Sometimes I'd even seek out a certain translation of a work because I enjoyed the beauty of the choice of word of the translator more than the authors underlying ideas.

(I've never gotten through the original of Whitman's Leaves of Grass, because I find it trite, but there's a particular Norwegian translation I loved - the authors intent was identical, but one presentation of it was beautiful to me in ways the other has never been because of the patterns of words rather than meaning)

Whether or not that intent or symbolism was there in a given poem, I found the process inherently destructive for my enjoyment of those poems, and I utterly detested the process because it felt like violence.

The one time I wrote a poem with a message was as a task in his class, and it was a sharp denunciation of the analysis of poetry. No analysis was necessary - the intent was brutally apparent and quite rudely expressed.

It is also the only poem of mine I've performed in 'public', which was a mistake of him, because it's perhaps the one thing that I have written that has met with the most universal approval among those who heard it, and it hardly improved the attitude towards the analysis of poetry.

I still find pulling art apart to often be brutally destructive and occasionally insulting in it's often shallow insistence of knowing intent that usually is without actual evidence and mired in dogma.

I don't mind people finding meaning in knowing more about how it was created when the creator of a piece of art wants that context to be known or part of the work, but I feel very strongly about assuming intent even for human art, because to me at least, for what I wrote, my intent usually was to write without any deeper meaning or symbolism, to evoke emotion.

For me, for what I wrote, picking it apart ruins that on every level in ways people rarely are able to undo for themselves.

It's like trying to reassemble a cadaver.

People can find their own meaning in anything, and make their own choices, but so much art snobbery revolves around that assignation of a dogmatic interpretation of intent as "correct" and objective that often feels outright disrespectful to assume to me.
Woah this is ridiculously good. You've done a good job here working off Pelias. I did find managing the Elasticsearch cluster for a production instance of Pelias hopelessly annoying.

Remarkable.
Okay, since you're apparently never going to respond to the actual issue about why (e.g.) jacking up the money supply by pushing buttons at the Fed and Treasury doesn't have the same effect as running the printing presses (more so, in fact; as I pointed out there's a limit on how fast presses can run), I think we're done.

First you tried to deflect by going off on my mistake about why M1 increased so much, even though that was completely beside the point -- although it DID increase massively, just not as much. This is akin to your pedantic non-argument about how increasing the money supply doesn't generally involve running physical presses.

Now you're trying to deflect by calling me a "demagogue".

I will ask you one last time, and if you don't give me a straight, non-evasive answer (which you won't) we're done.

How, in actual effect, does increasing the money supply $n trillion by running the presses faster differ from the Fed/Treasury increasing the money supply by typing numbers into a keyboard?

Hint: it doesn't. But you can't admit it because that would demolish your entire thesis.

Bye now.
That's just patching fetch for suspense stuff, and suspense is literally about rendering state.

Sure, not a pretty workaround, but nah react isn't trying to be in charge of fetching here.
I think you misunderstood “use restrictions.” I interpret it as “anyone can use the software built with this source code themselves.” The GPL and MIT license don’t have any use restrictions. (In the case of the GPL, there are restrictions on distribution, but that’s different.)
Show HN: Get notified when your favorite Twitter handle is available
That's right. They're what very online people would called HR-pilled.

You: but *sometimes violence is justified, no?

HR: No.
In five years the world will be identical to the present. In 15, it will be unrecognizable.
Absence of bullying doesn't mean absence of discipline.

In no situation bullying is a good thing. Bullying is devastating and an unhealthy way of teaching things.

You comment is basically saying "bullying didn't work on you because you were too weak". That's borderline victim shaming and completely insensitive.

Courage has nothing to do with coping with bullying, and you should not need courage for daily interactions with your parents who ought to be your support instead.

You need validation and constructive criticism to grow and bullying is kinda the opposite of this. This validation and constructive criticism will give you the chance to build up self confidence which, in turn, may also you to grow a "thick skin". No need for bullying, which usually takes away your self confidence.
> VNM applied in the realm of ethics is definitionally utilitarian.

I assume you are thinking deontological ethics, virtue ethics, etc vs utilitarianism, but non-benthamite utility functions exist. Actually, if they didn't I assume a lot of AI doomers would be less doomy, as quite a few of them are utilitarians.
> Parents having caregivers hardly comes into it at all.

For me, it does, an awful lot. Being a caregiver to my parents has implied a lot of existential suffering and emotional agony. Think about it: the people who raised you are going to die slowly and perhaps painfully and you are going to see it without being able to do anything. I feel I would be very cruel by giving that future to a child I love.
One can help on a technical level without providing fully baked solutions.

Finding (or developing) real or at least reasonable uses of Erlang where performance is lacking in an unreasonable way.

Narrowing those use cases into a minimal test case.

(Much harder!) Finding a way to make such a test case work significantly faster, even if it breaks other things, can be a helpful step towards a polished improvement.

Some areas of OTP are very well polished and difficult to improve. Some areas are kind of the first thing that worked and it was good enough and never got much polish. There's less of the second kind than there was before, but when you hit those, it's often pretty easy to improve, and a bug report or proposed patch will likely be processed by the upstream team quickly.

I find Erlang amazing, but it's important to note that a lot of OTP is written in Erlang and usually easy to read. Most of the C code is fairly easy to read too, once you get used to it. It's a very approachable ecosystem, and I think people should be encouraged to peek under the hood, and tinker.

Here's a free idea for performance improvement, although it may not be good. Erlang's JIT is very simple, because it needs to run for every beam file at load time. So this idea comes in two parts. a) Could you get a minor reduction in beam loading overhead by caching the native code output of the JIT processing. b) Are there ways to improve the JIT output that are too slow to run just-in-time, but could be run to improve the cached output and loaded in the future. Of course, there's the elephant in the room of making sure cached native code is compatible with the current BEAM, in case one JITed with a newer or older version. And the current JIT is successful by being simple, an earlier version of JIT tried to output optimized native code and was too complex and was abandoned. I think a motivated person with a good amount of experience with systems programming, mixed language experience, and willing to beat their head against the wall of dlopen or however the JITed code gets loaded could learn a lot working on this. And if it works or at least shows promise despite not completely working, share it and see where it goes.
Why's that? They can get the weight down to barely more than glasses, and with good pass through video and battery improvements... You'll be pretty unencumbered. Certainly not more encumbered than being glued to your laptop on a desk.
I was hoping he was actually going to formalise the notion
My guess - use the API and make one?
My friend sold boats for over 10 years. He said women love going on boats, but he never saw a woman buy a boat in his life.

Women love apple products, but if you look at who is splurging on multiple high end apple computers with multiple monitors it's gotta be 95% male.
https://t.me/indeec_1937/14672
I guess it's "open core". "View license"
That's either going to happen or it's not, but I don't think everyone being dead is an acceptable way to force it to be wrong.
This is one of those sentences that are triggering/traumatizing for those who HAVE gone through the experience. And not even for a popular project!
It seems like our careers could just be snuffed out instantly with little recourse available.

You’ve likely heard this sentiment before but it’s the right one so I’ll be the one to post it today: your job is not your purpose, and the economy is not the society. Obviously your whole comment is well founded and relatable, but I think this is the only cure for your anxieties. The world is a beautiful, beautiful place, with many more wonders to offer than the typical laborer is accustomed to. If we eventually have a society where everyone is happy with what they have and there’s no work left to do, that would be a cause for celebration IMO.

This is all assuming that the intelligence explosion people are wrong. If they’re right… well, let’s hope they’re wrong.
Paul McArtney's lost Hofner bass returned
I drove around today listening to the most recent Lex Fridman podcast, in which the founder of Boston Dynamics was describing replacing human labor with machines that were capable of learning by seeing. I have family in the trades. I pursued tech and fell in love with the field. Listening to the interviewee, I began to feel sick to my stomach at the glib description of what amounts to ripping away peoples' livelihoods with plasticized fingers. Work is equivalent to worth. We are not biologically or sociologically prepared to differentiate the two.

How easy it must be for Sam Altman to drag the world kicking and screaming into the future. How pretty his offices.