skysight-inc/HackerNews huggingface dataset:
In hindsight, that’s because high school calculus doesn’t teach you how things work and just teaches you a bag of tricks so you can grind through problems. There’s a certain number of tricks you should know, I.e., you should be able to take some simple integrals and derivatives, but for higher math, you run into complicated things where the tricks don’t work or don’t exist. Some of the tricks are actually really useful, but you have to fully internalize where they come from, e.g., integration by parts just comes from rearranging the chain rule, and, if you know that, you can apply it to more exotic derivatives.

I did well in HS calculus but struggled in college math because the bag of tricks approach doesn’t work there. It took a lot of effort for me to undo the bad habits I learned from K-12 math and learn the good stuff, but it paid off.

Also, it’s well known that eventually professional mathematicians hate certain kinds of math. There’s the classic divide between analysists (those that do calculus-type stuff) and algebrists (those that do things like group theory, and linear algebra goes here). You don’t have to like it all, and something you don’t appreciate the first time you see it, you may enjoy later
I’m new to this idea and NOT educated in biology let alone oncology, but here’s a meta study that suggests early exposure to famine is associated with increased cancer risks, if tenuously: https://www.sciencedirect.com/science/article/pii/S127977072...).

Of course looking at the effect of famine on an adult populations would do more to investigate your hypothesis than the effect on developing children.

But famine seems a bit extreme, no? Aren’t there also regional studies that show regional dietary/nutritional factors that correlate with lower cancer rates?
Google earns a ton of money from people paying for keyword searches. Ai content increases the competition for these keywords driving increased revenue for Google. I wouldn't expect them to do anything about the so called problem, because it's only a problem for end users searching.
Yes, they changed their mind: https://www.theverge.com/2024/1/17/24042179/netflix-apple-vi...
... so they made their existing campfire SaaS app installable locally?
Hard to say really... if foreign labor is subsidized under communist strategic policy, than it is more of a loss-leader rather than rational competition.

Value blindness is often accepted in consumer markets, but can prove fatal in industrial or aerospace products. Hence the rules silly people try to work around to make more money. =)
What's the base rate to compare this against? For other social networks, for other websites, for society as a whole. My general attitude about meta is that it's cool to point out any flaw that might get people mad at them, but I just want to know if there is any reason to think this is a special problem they have. And, even though it's a double standard, I do get my hackles up when they start testing the waters to see how effective it is to imply that end-to-end encryption causes child abuse.
The connection between noise and the emergent consequent of that noise being autism is quite an assumption. Even with the gene in common
Which platforms do meta allow children to create accounts? To my understanding, they stopped allowing children on their platforms since social networks can cause major harm to children from things like bullying, and that children can't give consent to the model of data collections that meta do.
The level of cautiousness many feel about the risks of AI hallucinations feels a bit excessive in a world where many people can easily obtain chainsaws without the need to fulfill any significant prerequisites
Yet another example of how HN's automated title modification screws things up
Lazy Imports and Cinder accelerate machine learning at Meta
Good to know. I guess education in the US has local standards? I have this impression of the US not teaching proof because in a number of introductory math classes in my college, the profs dedicated chapters to teach basics of induction, how to write proofs, and etc.
Something like 4-5 days in a row of temperatures ranging from around -15C to -30C.
Can you be a bit more clear? Are you arguing Linear B remains undeciphered?
Ask HN: Has anyone achieved Douglas Engelbart's Vision?
hi hacker news.

i would like to know if anyone in software has achieved Douglas Engelbart's Vision?

that of the OnLine System, H-LAM/T, Bootstrapping etc.

if not, do you have anything that comes close to his vision for computing and collaboration?

something that would augment our ability to improve and our ability to collaborate and solve difficult problems?
Gut-Brain Network for Sugar and Fat Cravings Discovered
Not in the technical meaning, no. But the general public thinks anything "cyber-" has to do with the Internet
You may be right about the UK, but most of Eastern Europe, Central Europe, Nordics are better than the US (or the UK) to my perception and these sources I could quickly find:

- https://www.economist.com/news/2013/11/11/shoplifters-of-the...
- https://news.ycombinator.com/item?id=38129353
- https://www.numbeo.com/crime/
As an expert, do you think this might lead to easier discovery of much more selective GPCR ligands?

Agree finding new 5HT2A ligands is cool, what would be truly interesting is having a suite of totally selective ligands for the entire 5-HT receptor family.

I feel like a lot psychopharmacological research into a lot of mental disorder is severely hampered by

1) the complex interactions of the various serotonin receptors(and also with other receptors like D2)

2) the lack of truly selective ligands, necessitating a hodge podge of less selective agonists combined with selective antagonists to isolate the effects of specific receptor interactions(making it hard to do this sort of thing in humans). Or using knockout mice, which is also kind of dubious because you've now made a fundamentally different brain and are trying to compare it to a normal one. And that's sort of hit and miss.
What's the architecture specialized for? Like a GPU or something?
Isn't Messenger now end-to-end encrypted?
Nitpick: the VGA DAC has 6 bits per RGB component (18 bits total), so each of the 256 colors is chosen out of 2^18 = 262,144 colors, not 16 million.
Neurotypical people are overwhelmingly monotropic. Humans will often focus largely on the social aspect of the conversation at the cost of reason. Walk for an hour and not notice 99% of the information around them. Internal systems that select points of interest in the data coming in aim monotropism. It is an intended feature not a bug.

I don't think it has anything to do with autism.
It is with liposomal supplementation. This means that it has a surrounding lipid so microscopic balls containing the difficult to absorb substance (especially any thiol-containing molecular compounds) like Glutathione, can make it past without other peptides inhibiting its absorption.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389332/

Thiols science:
This research is informative for the topic of the role thiol compounds plays in the antioxidant system, of which, Glutathione is scientifically considered the body's master antioxidant, it recycling (think of "guarding") SOD (Super Oxide Dismutase) and Glutathione itself being recycled by Vitamin C.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041647/

I'm forming a hypothesis tonight, as a "citizen scientist", that the very reason why thiols are hard to absorb is because thiols are often helping to get oxidized lipids and oxidizing chemicals OUT of the body in the two ways that can physically happen. It seems interesting to me.
So something like an army of robots? This seems like a nation-state kind of concern. I guess we could imagine small private armies, but I would imagine that governments will constrain those the same way we constrain more serious weapons.

At any rate, we are a long way from having practical robots - let alone having to worry about an army of them.
And iOS isn’t a platform that you could. Everyone who bought it knows that. If side loading is important to you, get an Android phone or maybe a niche OS phone.
> And those are, naturally, people with a programmer’s mindset.

Digging this line! Even in the craziest hustle, there's still space for some healthy competition. At least there are still jobs for us humans. I seriously can't wrap my head around how our civilization will cope when AI robots snatch up all the human jobs.
The importance of being earnestly random: Metamorphic Testing in CockroachDB
They have "Messenger Kids" targeted at the under-13 market with safeguards ostensibly in place, and as far as I know children 13 and over can create FB/IG accounts.
Japan and Germany are vulnerable to Chinese aggression. The primary reason why a declining company like Micron was gifted a new fab in Syracuse NY is that their Boise fab is within range of a larger portion of the Chinese arsenal.
> but I needed a good reason that would justify the time investment

It should be understood though that there are cases when math(-like) language is abused, leading to overcomplication and obscurantism [1]. In mathematics, there is always the temptation of formalizing for formalization's sake. Indeed, 99% of pure math is non-constructive ("there exists a group such that", "the algorithm converges in O(N) steps"), as opposed to the practical CS and applied math ("here are the runtimes on real world data") which are likely the primary concerns of the HN crowd.

None of this can diminish the sheer impractical appeal of pure math and pure CS, not unlike that of poetry, but I would rather not oversell either of the two.

[1] A good illustration is a rant by Cosma Shalizi at http://bactra.org/notebooks/nn-attention-and-transformers.ht..., recently posted on HN.
World GDP/Capita is $12,234. Why would you use world population instead of US population? This discussion is clearly not serious so I'm not gonna respond further
Minimize LLM Hallucinations with Pydantic Validators
I disagree.

Just for the record your swearing makes you uncivilised. I was just offering my opinion. I’m allowed to do that. I was giving my professional opinion. All your replies not only make you look like you can’t take criticism but they are also IMO mostly poor and short sighted. However I appreciate your time and input and will try and reflect on them. Have a good day man and for what it’s worth Rockstar has always been one of my favourite companies over the past 2 decades.

My opinion is if I was management in that company I would accept my fate if such a transgression occurred on my watch. I wouldn’t be butthurt about people thinking I should be fired.
They found out if you die in the metaverse, you die in real life
To know might be a crutch, or a chip on the shoulder for another.

At the end of the day, self acceptance must come with or without diagnosis.
You can add barriers and policies but I've been astonished what parents will work around to get their children to use these platforms (I recall a family member using their ID to allow their 11yr old child on Discord).
echelon is proposing head or body transplants. It's not sci-fi because doctors have been able to do it with limited success since 1970. Yes it will cure cancer, assuming the tumors haven't spread to your brain. No, cancer is not HIV it is not contagious in the way that you think. https://www.cancer.org/cancer/risk-prevention/understanding-...
A waste of time. House requirements change all the time. So you want to set a design in stone, so to speak, instead of allowing the design to change over the years with changing requirements.

Look at the buildings (not just 'houses') that have lasted more than a few centuries. You will find that they are filled with kludges to offset the requirements of change over that time: like cables attached to the outside of stone walls instead of being embedded and hidden away as they normally are; or double-glazing retrofitted to small-pane windows; or foam sealant being applied to drafty gaps in walls; or false ceilings to reduce the ceiling height to reduce heating costs, etc, etc.

And many buildings are demolished not because they are no longer suitable, but because the location where they are is wanted for something else. So in that case, it wouldn't matter that the house is designed for 1000 years, it's just not wanted there anyway.
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Well, it seems that initially started with GPT4 but his costs were becoming high so he had to do something and had to do it quickly. Technically he could have written a few hundred responses himself while the site was still using GPT4 using the prompts from the users but that could have been slow (expensive)/boring, etc.
I don’t think the SDK is necessary for an iPad app to run unmodified on Vision, only if you want to specialize for the environment. However, I can see them maybe actively disabling their apps until they can test them, or perhaps they were buggy but didn’t think it was worth fixing given the limited user base.
I've started mentally dividing people into (i) app addicts who share their gps location with strava/trailforks and (ii) luddites whom I can invite to hike/bike on www invisible trails.

EDIT 'addicts' is indeed a strong word, but how else can I say "they feel bad when they don't turn on tracking"?
Per day.
Funny part is IBM is one of the largest users of VMWare and IBM cloud is based on Ubuntu .
I spend too much time on HN, but it is better than most things online. Certainly better than social media or YouTube.

One thing I started recently is a weekly digital sabbath: no screens on Sundays. I'm enjoying the change.
Every state sets its own curriculum, with varying degrees of freedom for the districts and schools within the states. The federal level has standards, which students are generally tested against in various standardized tests, that are tied to federal funding.

Multiple curricula can satisfy the same standards, at least on paper if not in practice. So states are, more or less, free to teach things how they want. However, they're also strongly driven by the textbook industry, which turns on the two biggest textbook purchasers: Texas and California. So a lot of the textbooks (and associated curriculum material) available for purchase in the rest of the states are driven by whatever those two states are pushing.
did cursor-fidgeting-while-reading lead to this discovery?
I’d be surprised if the PornHub one is legitimate.
You would be silly not to take a better algorithm. It doesn't matter if it came from sales, a student or a homemaker.

If you can't judge something on it's merits and must rely on other signals then you end up judging the envelope and not the message.
You've got absolutely nothing to be ashamed of.
North Korea's Most Advanced Drones Reemerge
https://archive.is/I0G1P
I don't share this take. If it isn't in my digital notes it may as well not exist. When I write with a digital pen it is much better. I also tend to write more useful information since I'm not worrier about space. When reviewing it is useful to have easy access to multiple colors, so I can express things more easily.
Ah I assumed you were correcting me, apologies.
It's not cheap. Given that it sounds like this is something you want to deliberately spend time on rather than just an app to use when you're bored it might be worth it but probably not so much if you can't use the knowledge professionally somehow.
All three of those men were backed by the most powerful states of their day.

Oppenheimer in particular is interesting because he headed up the most important, but least expensive and labor intensive part of the project. He was also not the main project manager, he only managed the lab. Groves filled the role of the main project manager, and was not a physics expert. In fact his expertise was project management. Groves book emphasizes that his role was to delegate to the correct people, and use his influence to get things done. In other words it was PMs all the way down.
If ozone levels are best kept low and disease is best kept at zero you could use carbon filters to remove the ozone eventualy?

The filter also removes pathogens but on its own i cant imagine it effective enough.

If it cant keep up you can still purge the room after use.
A book that has contributed to my sense of purpose, making it easier to focus on the few activities that really matter, and to let go of everything else:

Why We Need to be Wild: one woman's quest for ancient human answers to 21st century problems, by Jessica Carew Kraft

Summary from the publisher:
"A writer and mom with decades of experience working in Silicon Valley, Jessica Carew Kraft grew fed up with her life filled with digital screens and deep anxieties about the future of humanity and nature. She quit her job and set out to learn about "rewilding" from people who reject the comforts and convenience of civilization to live in nature using Stone Age tools and skills. A suburbanite with a husband, kids, and a mortgage, she learned to turn sticks into fire, stones into axes, animal skins into clothes, reeds into baskets, and bones into tools. Weaving deep research and reportage with the fascinating tale of her own experience pursuing this path, Jessica tells a remarkable story that illuminates the way we live now, how we survived in the past, and how each of us can choose to thrive in the challenging years ahead"

English, 2023
Publisher: Sourcebooks, Naperville, Illinois, 2023
"Lets go with the easier approach" is a bit worrying when it means potentially breaking security assumptions / legal assurances.

Though I guess it could be explained away by having something in the website's "Terms and Conditions for use". ;)
At any given company the stakes are about 0 compared to the manhattan project, so that kind of tracks.
Its an easier target. Its good to be social right?
It does favor users who have likely have better than average graphics devices, but it still is likely relatively right - especially as the numbers get high. It is based on ~250,000 data samples in the last week.
Encryption aids everybody's privacy, in the same way that roads aid predators to steal away with your children, and food aids predators by giving them nourishment. Ergo we need to ban encryption, ban roads and ban food. Anyone who doesn't want to ban food (and let me snoop on all their messages) is an evil predator - https://www.youtube.com/watch?v=LNYZo5yRVNk

Anything in the same sentence as "aids predators" throws context out the window and marks it as a vile and awful thing to anyone listening. Don't use that language, and don't let someone lead you by the nose into using that language.

Instead, talk about how end-to-end-encryption improves the safety of all users, including children, because it gives them control over who sees their messages, and shields them from criminals who would gladly snoop and steal their personal data. Banning or breaking encryption will not make children safer. What will make them safer is parents supervising their young children's internet usage, and teaching them how to protect themselves online when they're older - how they should avoid giving out personal information (e.g. to Facebook or Instagram...), how to lock down access so only their verified friends can talk to them, etc.
Well, they say you die twice: you die again, when you're forgotten. So in a way he ensured his immortality (with a good helping of luck through the ages).
Me and my friends found this drug conceptually hilarious back in the day and used to crack a lot of jokes about it.

Its apparently almost as strong as LSD, takes hours to start working and the effect lasts several days. Worse in every respect. Why would anyone ever choose it?
> Palo Alto Networks ... after reading product page after product page, we couldn’t work out exactly what product it was

Well that definitely tracks.
This is true, but there are no biological simulations in the mainstream models, just various correction factors with their own uncertainty. I wish they had biological data because then we would have more domains in which to measure their accuracy.
Unregulated | poorly enforced "big business" is no better and arguably worse.

The crux appears to be adequate resources to enforce standards

> a commercial reputation to defend (and deep pockets to go after in a law suit).

Meanwhile, in "the real world" sufficiently large businesses are routinely silo'd into seperate sub companies and those that are associated with disaster, product liability, deaths, etc are often mysteriously bankrupt or with insufficient funds to meet penalties of pennies on the dollar.
I would extrapolate from existing GPCR-targeting drugs, but the list is so long I can't really give a survey. As a protein family, GPCRs do a lot of different things but basically it boils down to signal transduction: there's something outside a cell and the cell wants to know that so it can respond. GPCRs mediate the binding of the thing outside to the surface of the cell, and transduct the information into the cell, delivering a signal to the nucleus, where the transcriptional machinery is manipulated to make new proteins (or stop making proteins). I left out some steps. This allows the cell to be responsive to the outside in a secure way, without the outside molecule coming into the cell.

The 3d structure of GPCRs is intimately associated with the cell membrane, with one end sticking out into the extracellular environment, and another sticking out into the interior of the cell. Simply getting that sort of protein, which is not soluble in water, was a massive challenge and the first structures didn't arrive until the early 2000s, when people learned how to crystallize GPCRs using detergents and other solvents that simulated cell membranes.

So many diseases are caused by misregulation of signal trandsduction... let's take some examples. Vasopressin is a drug that also happens to be a natural body product. In some diseases, people don't make enough vasopressin to regular the kidneys properly, leading to a form of diabetes, and simply giving people more of it helps reduce the symptoms. I guess in this case (not certain), people have mutations in the GPCR that receives the vasopressin signal that attenuates the signal "too much" and by just dosing the patient with a lot more, more signal gets sent inside the cell.

I think at least 10 nobel prizes in medicine have been awarded for research related to GPCRs, which has uncovered a wide range of medically relevant knowledge of physiology. The NERSC supercomputer "Cori" was named for Gertie Cori, who helped discover some of the core mechanisms in human metabolism during the golden age of metabolic biochemistry.

I think the simplest way to think about it is being able to target specific GPCRs is like being in front of a switchboard with buttons and knobs controlling every critical detail of how human bodies manage and maintain themselves.
Regardless of whether it's an intentional scam, if a client tells me they want to pay by cheque I'm going to be laughing through the entire "thanks but no thanks" response.

You might as well tell me you want to pay me with livestock and your most buxom slave girl, it sounds equally as barbaric.