skysight-inc/HackerNews huggingface dataset:
I totally agree. Although I'm not sure similar vouchers for antibiotics would be sufficient for the same success, as there are also logistical, financial and scientific advantages that have enabled rare disease drug development. Many rare disease being targeted are monogenic, providing a very 'clean' scientific mechanism, and higher success rates. The clinical studies can be small well defined population as pre/neonatal genetic testing is now routine, and supportive Foundations are often instrumental. Financially, insurers/payers have been amenable to huge per-patient prices in rare diseases because of low volume and often impressive efficacy.

Developing antibiotics has lower technical success rates. The medical need is more acute and distributed across more broad populations with much of them poor making patients 'harder to find'. Any novel antibiotic are typicaly held in reserve until after generation of resistance to all the current drugs, limiting volume. Commonly, physician and patient over-/mis-usage of antibiotics generates resistance, generating a limited 'valuable' life span of the drug.

There are many governmental/regulatory incentives being developed, and at least one industry-backed fund (AMR action fund) supporting early research but it’s still a challenge to build business plans for this.
I'm not sure what you mean by "make the way" and your working pc and stable internet connection seem to trivialize the pressures and very real limitations someone has while on parole and then subsequently after getting off parole.
A degree is simply a piece of paper that will open certain doors, but there is no guarantee it will get you through them. You can still open lots of other doors without it but some will remain closed or be difficult to open. Those are doors you might not want to go through anyways.

I don't have a degree and it has not hindered my 10+ year career. However, certain immigration related things I'd like to do are difficult if not impossible without it, but I'll admit that is highly specific to me.
I’ve heard of adafruit before but haven’t looked at their stuff. Will check it out
if anyone's interested in "independent" vim keybindings, made to work same in both insert and view modes (and a few different terminals), this is what i use for over.. 25years (?) Basically, few keys like old DOS PE2.exe or (later) e3.exe, and the like, then adding more with years. Like F2 for save, F3 for abandon, Ctrl-F/A for find forward/backward etc. Plus some other stuff that turns vim into kind-a IDE (grepping etc).

https://github.com/svilendobrev/svd_bin/blob/master/qini/_vi...

have fun
The actual title of the article is "What happened to EVs" and the page title is "Why America's electric car push isn't working". I don't know where the HN title is coming from, whether it's an update of the article's title because of precisely what you're advancing, or if it's heavy editing from the submitter.

Generally speaking the article exposes that the pace of adoption as stated by DoT didn't grow enough to meet their 2030 goal (i.e. The second derivative is going down), and goes on to explain why.

I think the article is fair, I think its title also is, I think the HN title is problematic unless you slap "than required to meet 2030 goals".
Ok so perhaps it's passion for growing pawpaws: sell better and that's more revenue to grow the operation. Perhaps it's living more comfortably, working to live not living to work etc.: sell higher at fewer markets, grow/pick less.

It may come as a shock to you, but I'm not a SV startup guy, and my own employment is certainly not income-maximised.
I know it's a motorcycle and a non-plug-in hybrid, but I think Kawasaki's offering of a 450cc ICE with a "strong" EV hybrid hits the sweet spot for me. You get 1000cc performance with the EV assist off the line, and 250cc gas mileage when just cruising.[1]

The longer wheelbase is going to make it less of a bike for the twisties than the dragstrip, but you can't have it all!

[1] https://www.cycleworld.com/motorcycle-reviews/kawasaki-ninja-7-hybrid-motorcycle-first-ride-review/
What is the avenue for people when the bank's owner says they're a high-risk candidate?
That’s my #1 rule; go (and stay) where there is either profit or a realistic path to profit.

Rule #2 is to play a role within that profit center which can be credibly linked to continued profitability. It doesn’t have to be directly making money, but it should be clear why the money will be directly impacted if I stop doing my job.
I couldn't disagree more. Imagine shipping an iPhone back to the 18th century. It wouldn't seem like an advance in technology over the kinds of devices that existed then. It would seem like magic. To me, this is just utterly obvious. And there's no reason to assume that future technology, possibly involving a deep understanding of the nature of awareness itself, if seen by today's people, wouldn't seem just as much like magic.

Not going to argue further about it, though.
This also properly aligns incentives. You continue to pay as long as updates provide value to you. As soon as updates provide no or negative value you can just cancel payments and stay on the version you like.
> To block that, you have to either tamper with the root servers, or get control of the authoritative servers.

I don't think so. The ISP can just reply to the DNS packets itself, without sending them to the root servers. Your local recursive resolver will think the response is from other DNS servers but in fact they would all be from your ISP.
This is bizarre, totally unnecessary and not something Wikipedia should be doing. The statements in it are misleading and not based in any sourced facts, either.
The company I work for uses these Cisco Meraki devices in their network, some of which support “Power over ethernet”.

https://meraki.cisco.com/product/switches/access-switches/ms...

With these devices, you don’t need to worry about a separate power cable for your network devices.
As a software developer, I rather work at a company that sells billions of dollars in merchandise, with a huge amount of software to maintain doing that and endless middle management ideas to build on (most of which won't amount to anything). Job security. Lots of opportunities to move around and nobody needs to know how the reference was about all the s-shows, when you go somewhere else.
99c on iTunes and later streaming on Groveshark killed mp3 sharing.

Spotify cleaned up the legalities of it, but they weren't (and still are not) innovating.
After discovering Muji Gel pens a decade ago I just buy them tens at a time (pens or refill sticks). They feel absolutely perfect and are very easy to obtain in Europe. It's a great feeling to find a product that works so well you can free your mind from the burden of search forever
Change a byte? :P
Sulphur dioxide is also a threat to life (humans, animals, and plants) and can result in acid rains
Going completely off-topic here but I have to ask: why spend that much for a Carrera T in a world the Cayman GTS 4.0 exists and is superior in virtually everything that matters for a sports car for significantly less?
The headline is false. Google is not Killing Cookies. They are killing third-party cookies. False headlines are not simplified headlines. Telling readers something that is false is not making it easier for them to understand, it makes them misinformed.
Show HN: Dashboard-Fusion merge Grafana panels from multiple dashboards
Recently, I found myself developing multiple Grafana dashboards that share panels. Surprisingly, there wasn't a dedicated tool to update panels in one dashboard and propagate it to other dashboards, so I created one[1].

This tool has been a game-changer for me. It allows seamless merging and updating of Grafana dashboards by combining panels from different sources. The real advantage is its ability to update existing panels while preserving the dashboard layout.

Curious to see it in action? Check out the example[2].

I'm eager to hear your thoughts! What do you think, and what other tools do you use for similar challenges? Let's swap insights!

[1] https://github.com/saucelabs/dashboard-fusion
[2] https://github.com/saucelabs/dashboard-fusion/tree/main/exam...
This is not constructive. Go be a loon somewhere else please.
In my experience, turning on entire pre-prod infra to e2e test earlier has been effective at reducing overall test suite runtime (in that we're running e2e tests often to the extent we spot + eliminate the flaky ones). And by virtue of e2e tests being good at finding edge cases, there's less emphasis on unit/integration test performance
A couple I am friends with tried to rent a car in NYC the day before Thanksgiving. Reserved a car online in advance, got to the rental place, only to be told that no vehicles were available. So instead of a car, they had to take the only form of transportation they could arrange at the last minute: the Megabus. Which is always fun with a small baby and luggage.

As I understand, theirs is a fairly common post-pandemic car rental experience.
It became frustrating to use google after trying stuff like bing chat and ChatGPT4 that does the search for you. I don't have to think about how to write the correct query. Those are becoming better extensions of the mind than google search.
My experiences:
1) programmer in IT department of major newspaper: disregarded as IT geek. very small salary. the worst office spaces.
2) senior engineer in software startup: rockstar treatment, stock options, all the things you would expect as office culture
3) senior consultant at IT consulting company: must basically be a sales guy who writes good PowerPoints. Maximize billable hours. What ever you do dont complete a project quickly or with minimum amount of code.

you can probably guess where I am now.
GDPR article 22 provides basic safeguards against automated decision making, thankfully. Imperfect perhaps, dofficult to enforce - but at least it is addressed.
$ telnet 1984.ws 23
Jobreel | Founding iOS Engineer | Onsite (SF) or Remote (US Only) | Full-time

Founding engineer for pre-seed startup focused on hiring in the service industry. This is an opportunity to make a difference by helping people from all walks of life find meaningful work in an industry that is all about taking care of others.

About Jobreel

Former Netflix, Airbnb, Meta team. We have the credentials and experience to make this business successful. Flexible with work location, in person SF or remote. Funded with a friends & family round. We value impact and know the difference from the appearance of impact. We value equality and increasing access to good jobs.

About you You find technical challenges fun and are down to learn what you need - from optimizing video streaming performance, to making animations. You move fast and make smart calibrations between done/perfect. You enjoy working independently and taking initiative, while also being collaborative. You love coding and have knowledge in:

- Swift

- SwiftUI

- AVFoundation w/HLS Streaming

You have deep empathy for folks in the service industry. Maybe you’ve worked in the service industry or have family in the service industry. You’re a positive, nice, upbeat person.

Interested? Reach out to careers@jobreel.io, with your resume or linkedin and a 30 second video about why we should hire you. Subject line: Jobreel Application - [YOUR NAME]
Nah, they just use their Starlink connections
Who could want a pickup besides people who need a pickup?
> autogenerate a state machine that will map each of the above 160,000 things, at any rotation within a 4 byte register, to a unique bin in a hash table. The state machine will have one 32 bit state register (16 bits to output, 16 to carry over to the next cycle) where every cycle a lookup in the state transition table is done, and the next 4 bytes of data XOR'ed on top.

You are basically describing a perfect hash, right?
The "bite" from McDonald's Coca-Cola is the best, a perfect pairing with the meal. The next closest aren't from soda, but sparkling water from glass bottles or ice-cold beer.
One of the most notable being the Iridium network:

https://en.m.wikipedia.org/wiki/Iridium_satellite_constellat...

Lots of interesting stories from their time (flares, collisions, market issues). It wasn't regular cell though, so maybe Starlink will do better.
I remember that thread! I briefly flirted with saltwater reef tanks before deciding it was way, way more than my ADHD-addled brain could take. Great summary of the key moments.
Even simpler. Just have a Dictionary mapping place name to ID. The slow path is "I haven't seen this name before and I need to store it, making sure that I'm not racing any other thread doing the same."

You'd have an upper limit on how many place names you can have. But no hard coding of what they are.
I'm guessing GAP.
> I've had to unplug and move the car because it finished charging before I was ready to leave the restaurant/store

And you bring this up as an advantage of EVs, it's mind blowing.
The CapEx -> OpEx push is also heavily tax based. I can write off (generally) 100% of an OpEx expense today (or, as I spend the money). CapEx expenses become Assets, which are tracked and taxed, and the business doesn't get to write off that spend immediately - it turns into a 'depreciation' write off, spread over the useful life of the item (sometimes 5, 10, or more years).
Real estate, vehicles, large equipment, etc. is generally all done this way - a CapEx gets you an asset or property, which is then taxed and depreciated.
Software licenses, insurance and other things can also be done this way (CapEx), depending on the terms and your accounting standards.
Your code is submitted (per parent comment)
> Queue

(nitpick) Correctly spelled but wrong word - you're actually looking for "cue".
It's not a thousand shortcuts, but more of a language for text edition, it's merely expressing what you thought when doing the tasks itself. Like:

"Search for the function name foobar; swap the parameters by cutting the first one up to the comma; delete the latter, and the space which comes after; type a comma after the other parameter, and paste."

The Vim commands are: / foobar <Enter> f ( l v t , " a d d f <Space> e a , <Space> <Esc> " a p

With VS Code, it would be like: <Cmd>+f foobar <Enter> "Carefully select the first parameter" <Cmd>+x "Place the cursor at beginning of the second parameter" <Delete> <Delete> <Option>+<Left Arrow> , <Space> <Cmd>+v

The nicest thing with vim is that I never have to touch the mouse for a lot of tasks. And I don't really think about how to edit, just what to edit as the language is very intuitive once you got it down.
Not open-source?
We are currently writing the guide. Meanwhile, our support team can guide you through the platform and answer any questions you may have. Additionally, if you need assistance with migrating a large number of workflows, we can also offer services to help with that.
Open Real Time Messaging System
If they found any life could they patent the genome? I'm not asking that correctly, but hasn't something like that been tried before?
If you own a garage, this is not a thing that happens. One of the best advantages of EVs that many seem not to understand.
Then indeed there might be. I'm not saying AI is useless in general, even though it might be totally irrelevant to my personal workflow. But my question is still what Copilot brings. Does it do what you describe? If not, what does it do?
The consulting company gig paid alright. and all the guys who stayed got really rich due to IPO. I left the second my options vested. Literally when the transaction went through... no regrets because it SUCKED
Slavery, presumably?
If you've used old style satellite internet and then used starlink, you'll know that this is not the same technology. Starlink has latency and bandwidth that doesn't even compare to the companies and satellites you are mentioning.

This is a tech and nerd forum. Let us be excited about new technology.
I don't think so. ICEs are designed to be serviced at authorized centers. F150 are utilitarian vehicles that can be serviced at any shop.
Why TikTok Parent ByteDance Moving into Biology, Chemistry and Drug Discovery?
Thats super cool for the ROV aspect. In university I was part of the underwater robotics program, and optimizing the tether was a huge aspect. We used a fiberoptic line for communication, leaving the rest of the cable mostly dominated by the copper conductor for power.

Any weight reduction that can be made for the cable internals is actually two fold. The cable needs to remain neutrally buoyant as to not pull on the ROV and not restrict the pilot. Less internal weight in the cable means less foam/other material needs to be added to offset the negative buoyancy.
Try contacting local small airports for information. Also, flight plans are apparently public record and available upon request.
> EV’s currently make the most sense for people who own a single family home or otherwise live in a community with readily available near-home chargers, where EV’s are on average more convenient than gas cars

If they are full EVs and not PHEVs they also make the most sense for households that have multiple cars where one of the other cars is a gas car. While the vast majority of trips are short, and charger networks are improving, a lot of people in the US drive longer distances at least occasionally, so it is much easier to replace one out of two cars in a household an electric car than switch to only using electric cars.

I think that once enough people have EVs and the charger networks are better this will be less of an issue, but a lot of people seem to downplay this issue, which I think is not a good idea, because I think there's a genuine risk that there could be a chicken and egg problem to mass adoption of EVs where the market of people who are able to use an EV in 2024 could be saturated before enough people are using EVs to build out the charger network sufficiently.
Nobody is trying to tell you what you should want.

But you should try to increase your accuracy about what you will want when making big decisions. We all should.
I really wonder if we will find these symptoms are caused by other viruses as well. Possibly candidate for chronic fatigue syndrome?
I've been in technology for decades, and to me the iPhone still seems magic, like alien technology
Yeah, I mean, I'm a full-time cyclist, so you won't find a lot of car love from me. :-)

But I do think there's a difference in risk. Aviation has a pretty dang good record, and I think that the tradition of transparency in comms and telemetry is a huge part of that.
Golden Orb Found at Bottom of the Ocean Mystifies Scientists
Right. It's the situation where if everything goes well it's wonderful, but if not it's hell. Until level-3 chargers are available every 25 miles EV's aren't viable for long-distance travel.

"I did a long trip no problem", you say.

Would that have been as pleasant if 10x the number of electric cars were on the road? If you had to wait 45 minutes for a charger to become available due to demand? I doubt it. I have an EV (not a Tesla, one on the CHAdeMO standard) and I love, love, love it for driving around the city, but I don't dare take it on longer trips. Even doing a lot of driving in a single day is dicey in the winter.

Until the charging network is as ubiquitous and reliable as gasoline pumps, EV's will remain a niche.
Today is the 25th birthday of Jabber, now also known as XMPP.
Not that I know boo about Clarke's "personal life"... Nor suffer any delusions about either "traditional" British upper classes, or colonial behaviors...

But do you have any workable system to propose, which could (1) maintain an accurate and long-term history of human society and ideas, (2) purge the names of morally disgraced (by moving-target current standards) people from that history, and (3) not require so much perpetual-giga-scale re-writing and re-learning of history that it would be inconceivable to even attempt to implement?
I recently went down the pen rabbit hole after starting a daily journal. I eventually settled on 0.38mm uni refills (UMR-83 gel and SXR-38 ballpoint) on energel infree bodies (metal clip plus you get to see the click mechanism at work).
Agree on the 3 orders of magnitude difference. 40W soldering iron will inflate post-it notes, 40W laser steel/stone engraving/cutting area.
So this is basically the inverse of the Good Samaritan law? If you do /something/ you might become liable because you did not do enough?
Technical headaches put the brakes on GM's big EV push
I too loved it, so I went to go see if I could steal the CSS for my own project. Can’t seem to find it though….
This seems super useful for remote sensors in hostile environments.
As well as the hurdles pointed out in the article, their Article 15 process (starting here: https://digitalerantrag.ksv.at/Dip/?request=auskunft-nach-ar... ) requires an Austrian mobile phone number. Personally I'd like to exercise my rights under Article 15 (since I am an EU citizen) but I don't have an Austrian phone number.
Also bound to C-h a

There is also C-h d (apropos-documentation)
But it fixed Hubble. Could that have been done any other way?
At first glance, it seems like another AI-generated page full of Amazon referral links. But looking closer, that's their shop site: mimicking Amazon's web interface pleasantly welcomes the user. That's a well thought UI/UX!
‘Giant’
> IO will dominate the running time for this, and JSON parsing will be second.

Memory bandwidth might dominate, but probably not I/O. The input file is ~12GB, the machine being used for the test has 32GB, and the fastest and slowest of five runs are discarded. The slowest run will usually be the first run (if the file is not already cached in memory), after which there should be little or no file I/O.
> "Also what do you mean by, "learned as a language" wrt to vim keybindings?"

Vim isn't a hodgepodge of ad-hoc keyboard shortcuts like, say, typical Windows programs ("where shall we put search and replace? Ctrl+H is free, done"). It can be seen more as a small domain-specific language for text manipulation. "d2w" is delete twice word (delete two words). "yy4p" is copy line 4x paste (copy this line four times below).

It's built of verbs (or operators, like delete, yank, make-uppercase), counts, movements (motions, like up,down,to end of line, to end of word, to start of next word, to search match) and objects (like characters, words, lines, paragraphs, blocks inside braces, text inside quotes, 'the selection') and you compose them together to say what editing you want to do on the text.

":help gU" will tell you that gU makes {motion} uppercase, that means you can do gUe to uppercase to the end of the current word, gU2e to uppercase to the end of the next word, gUfx to uppercase until the next x character, gU/thing to uppercase until the regex search for 'thing' matches...

and Vim being around a long time, it has a lot of different verbs, motions, objects to allow you to slice and dice your text just so for the edits you want to make.

Try

:help motion
:help word-motions
:help operator
:help objects
Lol, going back to those old mining towns where they pay you in company money and you live on company housing
Maybe evolution just has a full backlog this sprint.
Claudine Gay Is Not the Real Story
I agree that AWS is a software org, I am interested in E-Commerce in this particular case.
Thank you for response
An average AA battery will have 3-4 Watt-hours of capacity.

This 3V at 180mA is 13 Watt-hours in a day.

So think of it like consuming about 4 x AA batteries every day, or almost 1500 x AA batteries jn a year.

You can do a lot with that amount of energy. You won’t be powering a switch or computer, but it’s orders of magnitude more power than small battery operated devices can use.