skysight-inc/HackerNews huggingface dataset:
but, it also sez the following : "They also demonstrated that the compound is fully absorbed via the GI tract and totally eliminated from the body in 10 hours." so, not sure what causes the increase in life-span. although, the cryptic "attenuation of age-associated increases in oxidative stress" does hint at something, probably the effect that this combo causes as it is moving through the GI tract ?
I find myself a little sceptical of articles on a website called "extreme longevity", to be honest...

... also, skimming the linked paper, the largest sample I see is "sixty rats randomly divided into 10 groups of 6 rats". I'm not sure if that's really large enough to draw any solid conclusions, and I don't see any P-values for the lifespan data -- but I freely admit I'm neither any kind of biologist nor a stats expert, so I may be talking rubbish.
I've just migrated to SlimFramework for one of our biggest projects. It is all I could want in a framework: it provides routes, basic structuring, middle ware, views, and leaves the rest up to you. This made it super easy to switch, as I can use my own ORM and was able leave most of the structural logic intact.

The slim framework docs are perfect, the code is clear and the forums are great. I especially like that it doesn't force you to do everything in one predefined way, making the learning curve nice and low
I'll have to find some time to settle down in a deep leather chair with my smoking jacket and a snifter of brandy for a fine evening of reading through someone else's code.

Sounds like fun!
Github is a glorified repository. Sorry, but any "social network" that requires code pushes isn't intended for that. :)
Learn to code with this handy flowchart
Article: http://extremelongevity.net/wp-content/uploads/C60-Fullerene...

The part getting the attention has to do with longevity; for that part of the article, data comes from "[t]hree groups of 6 rats".

This was a single experiment in which n=6 rats received the C60 ('buckyball') composition, n=6 received just the oil, and n=6 received water (which can cause adverse effects in rats). Interestingly, a protective effect of oil gavage in some rat strains has apparently been observed before ( http://www.ncbi.nlm.nih.gov/pubmed/3591539 ) but that's a bit of a distraction since the focus is on the C60.

All treatment stopped after a few months when the first control rat died. Given that the half life is 14h for peritoneal injection of this particular substance, there should have been nothing left of it after ~70h. How it continued to affect rat lifespan for several months afterward would require explanation.
Connect with these people:
http://www.meetup.com/DC-Tech-Meetup/
That's impressively wrong, well done.

Here, I looked up the relevant portion of the comment thread for you: http://news.ycombinator.com/item?id=3262469 . You supported your claims about Apple inventing multi-touch with a claim that Apple had trademarked a specific definition of multi-touch - thus allowing you to dismiss out of hand people citing earlier screens that supported multiple touches. You accused at least one of these people of lying. I showed you that you were wrong, that the trademark application you cited had been denied because the term is generic. Hence, other people's examples of multi-touch interfaces were perfectly valid.

Another user cited a cofounder of Fingerworks stating that multi-touch was not a single innovation: http://news.ycombinator.com/item?id=3263335 .

I'm not really sure what 'political and ideological reasons' you think I have - I have no idea of your political history, and have only noticed your posts related to Apple. I am a happy user of several Apple products and, on the whole, admire them as a company despite certain faults. I'm just not a rabid fanboy.

> The problem is, so rarely do I get counter arguments, that such defenses are not often necessary.

Funny how you stopped arguing at the exact moment your position became indefensible, and were so keen to do so before then. I'm honestly finding it hard to work out if you're trolling me or not.
I'm so happy you hackernews people like 0x10code (it's my site) :D
The logic of quantum mechanics - Take II
Make that 3.

I've always wondered why game rules have to be so rigid (use a state machine) and always thought it was the technology but what you described makes sense and makes use of older technology but in new applications.

I just took one AI course while in college but got hooked ever since.

Question: Can you expand on the motivators and deterrents concept? Specifically, how do you relate something like "getting food" with the world objects? Assigning points to specific world objects(apple, cow, chicken...) seems to get us back to a state-machine like game. Humans have experience (memory and patterns) to guide them, what would the characters have?
Actually ..

I happened to be in the office of someone who was doing language translation on the PC version of PoP at the time; He had a copy of the source code for that, and it was C.

That was twenty years ago. I only got a glimpse of one screenful of code, but I remember feeling special for that nonetheless :)
(Really) useful resources on estimating:

- http://www.mountaingoatsoftware.com/presentations-estimating...

- http://www.mountaingoatsoftware.com/books/1-agile-estimating...

(I'm not affiliated with Mike Cohn but took his estimating and planning course and must say it's worth the money).
I'm well aware of Lady Gaga's songwriting ability and talent as a piano player. However, the Gaga persona seems to be her of her own creation, and I'm quite sure that at least for her first album, she wrote most of her own material.

I'm not blaming anyone - the music industry is a strange beast. But the true rarities are people like Gaga (as much as her I dislike her music), who can write and perform their own material well.
The tolerance - how far out one may be for the estimate to be accepted and the answer shown - must at all times appear reasonable ... The student should never feel that an estimate was unreasonably rejected, and on the other hand should not find an odd guess being accepted

The inventor had considered this question for 14 years while developing this calculator.
Try the command line program "enscript". It has many options that control the output formatting. For example, you can print pages in landscape orientation, two-up, with source highlighting and line numbers.
do it as an app or widget they can install on their profiles
If nothing else, I'm sure the thought of extending the life of their favourite pet would make a few rat owners happy!
The reverse situation for Australians is actually quite easy, for the most part if you have no income from or assets in Australia you're not required to file.
And there is also snippet compiler: http://www.sliver.com/dotnet/SnippetCompiler. Unfortunately, it only works up to framework 3.5, but that's good enough in many cases.
How to Make Things Happen
I did the same (clear on startup), but then Firefox stopped crashing daily, doing it once a week doesn't seem enough.
"Microsoft still has the audacity to charge several hundred dollars for their OS."

That's really disingenuous, given that

1) the consumer versions of Windows traditionally cost less than $100

2) Microsoft doesn't make money on hardware, whereas the cost of Apple's OSes is priced into Mac hardware

You don't get to tut-tut Microsoft for an expensive OS (that runs on the consumer's choice of commodity hardware, cheap or expensive) when you pay a premium on a Mac all-in-one computer. You can justify Apple's OS pricing as being easy to stomach all you want - ultimately it's your choice to buy into the intended psychology of their pricing strategy - but don't try to paint that as a rational, fair comparison.
Whole-genome sequences of supercentenarians reveal longevity clues
Cool thanks. That's really interesting.
It is not just a lower price. They have dramatically changed the pricing. Which in the context of settled and steady pace industry causes disruption.

PS. Seth Godin had made a note recently on how to cause description in the market http://sethgodin.typepad.com/seths_blog/2012/04/on-making-a-...
I'm an old C64 and Amiga guy - the first time I saw x86 code I was horrified. 16-bit real mode or not, when I finally gave up on my dying Amiga was when I stopped writing assembly as well - x86 assembly was where I drew the line. I didn't want to make that transition.

In other words, I don't agree that 16-bit real mode is much better. Now, mdern x86_64 code is starting to get tolerable, with more orthogonal register, for example. But I'd rather chew off my own hand than be forced to write any large amount of 16 or 32 bit x86 assembly....

Then again, I'm horribly opinionated about programming language syntax...
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very well done. I like the mini demo too.

Where do you see a revenue stream?
You're probably already aware, but if not: Magic Lantern alternative firmware for the 5D makes it much much nicer for making videos. In the right hands (which are not mine ...) I've seen it make low-light video results much, much better.
That was endemic at the last company I worked for. Someone would come to you and say, can you do X. Well no, because (for example) we don't have the kit and there's a lead time of 3 months on ordering it and the budget's not been approved. You would explain this, and then the person would go to your manager and say "he refused to help me". So yeah, someone else can deal with that.
The "disruption" is the promise to get 12-bit RAW out of it for this cheap. It isn't necessarily disruptive (RED cameras are still competitively priced, considering the budgets of productions that could harness what RAW has to offer), but it's an interesting promise. Then again - just because it's RAW, doesn't mean that it's divine. Before a raw signal becomes a RAW file, it still has to go through a Wavelet/DCT compressor and might end up not being very useful. RED cameras have between 1:3 and 1:18 Wavelet compression. It's RAW, so nothing is pixelated, but you can't argue with entropy, and trying to only gets you more noise.

In other words, RAW could be a buzzword, Blackmagic are new to sensors, this might be a big hoax, but having a perfect track record with Blackmagic products so far, I'd consider switching, which is sort of what you're looking for when you say 'disruptive'.
Ha! What do you mean u saw Viagra ads? Where?
Judge Preserves Megaupload Evidence For Now, Gov Tries To Pin Blame On Hoster
I hear people repeatedly saying "work-life balance". Work and Life are not different things. Everything is life. If you don't have life, you can't work. It's as simple as that.
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I agree. A lot of the points in this review are simply irrelevant. They're talking about support for HDMI and other features not being available in default Debian distributions, the abililty to render Quake 3 (seriously), and other ridiculous comments.

If you're a hacker/tinkerer/kid learning, the default distribution isn't likely all you'll be using anyway. And if you're buying the Raspberry Pi to try to get a cheap gaming system, you've completely missed the point.
Majorana fermions possibly created in lab
Next über cool agile project management tool
Best practice SharePoint Intranets
Ask HN and Ask PG: Anyone not get any YC answer email at all yet also?
Haven't been able to focus/sleep much yesterday (euro time) so waking up this morning was hoping to have some sort of answer. We are moving forward anyways but it would be nice to know YC's response :) Checked email (every account I have), spam folder, etc. Anyone else in the same boat with no email? All the other co-founders have checked as well.
Depends in what you like to do at work. Writing code isis boring most of the time. The most exciting thing that can happen is trying to figure out a design for a very complicated problem and sure, that's fun stuff. But I find handling production emergencies much more exciting. Whatever you test for, whatever you monitor, one day you find the system down or misbehaving in a completely unexpected way. And if your service is supposed to run 24/7 worldwide, someone has to fix it, preferably as soon as possible and making sure as few people are affected as possible.

In short, different people like different kind of work. And that's ok.
http://lexicon.ft.com/Term?term=demarcation-dispute
I like this post. I'd like it if we could get studies/posts on:

1) A/B testing of users' responses and revenue outcomes on native vs wrapper implementations of apps

2) Webkit performance metrics in wrapped apps on different platforms (e.g., exactly how slow is the app on the 4S, why, and can this be mitigated?)

3) good approaches to interfaces that don't confuse or put off the user but are simple enough to run smoothly in Webkit

I'd love it if anyone could point me to enlightening information on these topics.
The bitmapped fonts were actually discovered via a leak of the 0x10c code. We'd certainly thought of it before then, but the leak was what sparked the implementation. This version of Minesweeper appears to overwrite the default font with its own custom graphics.
Now it doesn't seem to be reachable.
I would also apply to a start up hosting program. Many hosting companies offer big discounts or even free hosting in exchange for a "powered by" on the bottom of site. Not going to solve your problem but at least reduce monthly cost.
Ask them what they expect - and see if you can and want to match their needs. Profit will come natural.
Read CSV File & Retain Exact Date Format, Enhanced Shape Rendering
The long awaited version of Aspose.Cells for Java 7.2.0 has been released. This month’s release provides support to retain the exact date format when reading CSV files: the dates will not be changed. We have also made some enhancements regarding shape rendering in our internal source modules. Finally, we have fixed a few issues regarding charts and other drawing objects. This release includes plenty of improved features and bug fixes as listed below

•	Maintain exact date format in reading CSV template files
•	Cell references were changed when column names are in lower case is now fixed
•	Shape’s text was not wrapped fine as what is shown in MS Excel is now fixed
•	Issues Transparency changes are fixed
•	Chart become black after re-saving XLS file
Notion Capital secures $100m for new fund to invest in Cloud Computing companies
I disagree. If your project ever gets packaged by a distribution, they will want to split the tests (and docs) into a separate sub-package with different package requirements or even discard them altogether. This will make that job a little difficult. And not only distributions do this. There are organisations who choose to package and deploy projects inside rpms or even bash scripts. Keeping the tests separate from the code just makes things a lot clearer and easier.

Tests that need to be run in production are probably functional or integration tests (Although even those should probably be run on a test system, not the actual production server). These should be separate from unit tests. Will you then have a whole tree of test subdirectories in each of your python submodules? test/unit/py, test/functional/py etc.
I would try and use a couple of methods. Firstly highly targeted ads are pretty much a no brainer. Look at ultimate-guitar.com - they are constantly pushing video lessons etc.

Use the data you have and display the most relevant ads possible a la Facebook.

Secondly, I would consider a low cost premium model. Most musicians are desperate to promote themselves so a few dollars a month to get in front of nearly half a million viewers is good value.

You might find many people are looking for band mates as well, a premium model could make this process easier for them and I think would be well worth a few dollars. With half a million users you don't need to get many premium subscribers to earn a decent living from this.

Finally, I would try and contact some advertisers and maybe even record labels or something directly and see if they have any suggestions. They likely have more experience and will probably bite at your ankles to get some exposure on such a targeted network.

Bottom line, try multiple revenue streams and test, test test!

Good luck!
It's standard.
Why do you remove .pyc files?
Can you recommend a good alternative to Gmail? Also, are there good tools out there for exporting Gmail data to a different service?
IKEA's integrated living room furniture with integrated television and audio
Fast simulation of Laplacian growth
Nike Lebron James VII
And if memory serves it's been through at least one, possibly two ground up rewrites since then.
What is travel insurance
You need the travel medical and health insurance to protect your vacation investment or to cover our medical needs while fly to abroad
Original press release for those of you who speak Swedish: http://www.ikea.com/se/sv/about_ikea/newsitem/2012_uppleva
It won't disrupt the camera market as much as the world of indie movies, where it fills a void between top range consumer products and unaffordable pro gear.

It will tremendously improve the image quality of low budget movies, and probably enable people to make movies that wouldn't otherwise have been made, especially in the poorer parts of the world.
What makes you think CryEngine can't run on older hardware? As a demo, they're naturally showing the engine at its best.

Games "last" quite a long time, too—by catering first to the high-end and then downsampling to be able to run on older hardware you make things "future-proof". When you release your game on iOS in a decade, it'll still look great :-)
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It's not meant to tell you anything about the project. It's meant to stay out of your way and give you instant access to the areas you're interested in: code, docs, tests/example code etc.
Bin Laden family 'to leave Pakistan early Wednesday'
See also this (http://news.ycombinator.com/item?id=961713) discussion about the source code documentation.
I'm trying to get my head around it. What type of simple use cases might such a small computer help with?
> Why isn't work optional?

This is what the German Pirate Party has in it's manifesto:

11 Right to secure livelihood and social participation

Each person has the right to a secure livelihood and social participation. Respecting and protecting human dignity is the highest commandment of the German Basic Law. People can only live in dignity if their basic needs are met and their social participation is assured. In our monetary economy, this requires an income. If an income can only be achieved through work, we must assure full employment to protect all people’s dignity. This is why full employment has been a major goal of our economic policy in the past. There are two paths by which we try to achieve this goal: Through economic measures which aim to create jobs or through publicly financed jobs with the main goal of securing people’s livelihood. These are both detours which require substantial public funding. If public funds are used, however, this must be done as efficiently as possible. Since the goal is to secure an income and a livelihood for everyone, this income should be guaranteed directly to each individual. Only this way can we protect the dignity of all people without exception. Just as we provide public security, traffic routes and large parts of the educational system without a direct compensation, a secure livelihood must also become a part of our infrastructure. We Pirates are convinced that the overwhelming majority of people will seize the chances provided by a secure livelihood to develop their full economic and social potential. A secure livelihood creates room for self-determined education, research and economic innovation. It enables volunteerism, e.g., taking care of relatives and children, independent journalism, political activity or creation of art and free software. This benefits our entire society. This is why the Pirate Party supports solutions which guarantee unconditionally a secure livelihood and social participation while sustaining and enabling economic freedom. We want to prevent poverty, not prosperity.

(from http://www.piratenpartei.de/wp-content/uploads/2012/04/parte...)
Since Dropbox (and presumably Google) store files only once globally, mapped to the file's hash, it makes me wonder when Google (or Dropbox?) will let you search and then add anybody's (public) files to your cloud account with a single click.

That means no more downloading from some slow web site, and then uploading it to the cloud again. Since Google most likely already has the file you're wanting somewhere, all you'd need to say is "I want that file, too" and it will be added to your cloud account. Google could do their own version of MegaUpload pretty easily that way...
I'm not a musician, but I have some friends who dabble with music. I've seen them hunt for guitar tabs online to learn new songs, and it always looks like a sad night of romance with Notepad. Is there a better system for sharing tabs than a basic text file?

Either way, how about a more elegant system of recording tabs that can also be sync'd to streaming tracks (like SoundCloud, except with scrolling tabs instead of the spectrum graph) or sync'd to YouTube videos.

All this talk of monetizing and better user connections is great, but what about better technical tools that make the actual creation of music easier? Build a garage of well-loved tools and they'll finish the rest of the house for you.
Trying derby.js out now. Just so that you know you can write in Javascript and/or Coffeescript but the internal code and the examples are written in Coffeescript.
> they chose a proprietary codec

A codec which no single party controls and is free for anyone to include in their video decoders.

> not in terms of "openness"

I'm not claiming Apple is "open" and nor is Apple. The one who is claiming to be open is Google, or Brin to be more specific.

> they'd support WebM.

At the time of writing, WebM is still not an option for mobile devices as it lacks support for hardware acceleration. Playing a WebM video on a mobile device would drain the battery at an unacceptable rate.

The only party claiming to be "open" is Google. And to the untrained eye Google looks very "open" with all its open-source projects. While both Facebook and Apple have their own open-source projects.

But these open-source projects don't necessarily make a company any more open than its competitors as long as their main asset stays closed:

- Google's main asset is search, closed
- Apple's main asset is the iOS platform, closed
- Facebook's main asset are the user profiles, closed

And now Brin is blaming Facebook for not opening-up the user profiles.
So what exactly are you proposing for a situation where the system fails for a large number of people and it's not a platform / sysadmin level issue? Assuming you're running 24/7 service with sla in place... Basically you need someone who knows your code and knows how to code.

To go with your ship analogy, no, the ship designer is like an solution architect who may never code any of it. In reality cruise ships carry whole engineering / maintenance teams on board in case of problems. I wouldn't be surprised if many of them were involved in building parts of some ship in the past.
Microsoft reveals Windows 8 editions, ARM version to be called RT
The idea of crowdsourcing venue info for mini-tour assembly is an interesting one.
Creators of On-line Narcotics Marketplace on the TOR Network Arrested
Because once you remove people's payment for something, you remove their right to make decisions about the things they would have previously bought.
Betting My Life On Transgender Hackers
Loved this ad :)