skysight-inc/HackerNews huggingface dataset:
While it's nice from a technical perspective, this is unlikely to lead to a cancer cure. Having worked in cancer drug development, I can tell you, there is no shortage of cancer targets. Researchers have a list of targets they want to hit, and chemists are pretty darn good at designing small molecule compounds to hit them.

The problem in cancer is not that we don't understand individual proteins or the way that drugs bind to them (the problem being solved in this article). It is that the biology of cancer is a crazy web of highly complex interactions and feedback loops of which we have a pathetically rudimentary understanding. So even when you think you're hitting a target that should kill the cancer, you find out there's some side pathway that spools up and limits the drug's efficacy (or worse, the cancer cells actively pump your compound out). If I recall, something like >95% of new cancer therapies fail in clinical trials. Most of the failure in this drug category is due to lack of efficacy (even though they hit a target, they don't do jack for treating the cancer). If you could make that number 85%, you'd probably be a Nobel contender.

Unfortunately, there's no digital route here. What needs to be done is a lot of slow, messy "wet bench" biology. There is no electronic shortcut to understanding how living cells work.
If the primary use for these really is to help find the car in an event of an accident then why are there penalties in place for circumventing the tracking. Shouldn't this be as politically controversial as forcing me to buy health insurance?
I both like and use CoffeeScript, but the video does show off one thing that i personally quite dislike about it.. Implicit returns (which I love in ruby..).

When trying to port over some applications to coffeescript, I had to revisit a whole lot of my functions to add in an empty return; line after code like:

test: (m) ->
m(i) for i in this.set

Since I didn't really expect them to build up and return arrays of the results of invoking m, which at times could result in a method that would generate gigantic arrays that I would subsequently throw away, killing my performance.

I probably should have expected that, sure, and if you don't have to deal with too much data it probably won't matter.
Any plans on adding additional traffic drivers beside content, such as interactive fitness tools?
Jon Stewart had a hilarious sketch earlier this week on this increasing tendency to throw around the term so lightly:

http://www.thedailyshow.com/full-episodes/mon-april-16-2012-...

around 7:00.
Subways/trains do this!
You don't need self-driving cars to make this world a reality!
There are plenty of free images (you only get charged by the AWS resources used, not the software itself)
Yeah. I always have trouble linking to these folks (even though they're on-target a lot of the time) just because folks dismiss it out of hand.

Here's the source:

http://thomas.loc.gov/cgi-bin/query/F?c112:3:./temp/~c112n8J...:
Is there any documentation for this process? Our non-profit had to shut down our Stripe-based donation page because it was being used by credit card thieves to validate stolen credit cards. Stripe told us addresses are only validated when a charge is executed, meaning we would then have to issue a refund if address validation failed (and eat the transaction cost).
I've taken a different approach to solve this problem (http://substancehq.com/). It uses mustache but does the rendering on the server side. My aim is to make it a lot better thank jekyll, because in my experience, jekyll doesn't have the best feedback cycle for editing → publishing. Sure, you can use the editor you like to write the blog posts, but, polishing them after publishing is a realy pain. Would love to hear feedback about it :) http://substancehq.com/
It's funny, because we had this in the mid-90s.

And by funny, I mean sad.
Oh, sorry I missed that!
Archaic C-level execs are still making the calls. This isn't unexpected.
The other value add is for insurance companies. They can use that data to alter rates.
That's mostly because their target customer is big enterprise who feeds on buzzwords they can feed to upper management. It's similar to the websites of SAP, Oracle and Intel, which all have the same qualities:

- No up-front pricing, you need to get a quote

- No screen-shots, you need to see a prepared demo

- Any contact what the company results in assignment of an "account manager", the used-car salesman of the software industry.

- Lots of testimonials from people you've never heard of talking about software you've never heard of using the very same buzzwords found on the website.
Parachutist Dilemma - a parallel programming problem
Oatmeal about difficult of watching Game of Thrones: http://theoatmeal.com/comics/game_of_thrones

and how I feel as a non US resident:
http://theoatmeal.com/pl/game_of_thrones/nz
Lol=vote
Good luck getting more votes.
If RSS didn't take off, it cannot be ascribed to malice from browser makers: even Microsoft at one point backed it right into Windows, they still support it in IE9, there is a component everyone can access that will deal with scheduled retrieval for you, so you could write an awesome windows-based feedreader tomorrow. Mozilla gave it a chance, half-heartedly (their implementation was terrible). Google didn't push it into Chrome, but they built the de-facto "Definitive Feed Aggregator" and supported it widely. Even standard-hating Apple built it into iTunes.

The truth is that RSS was a cool technology searching for a reason to exist. It managed to find it on occasions (podcasting is still alive, twitter basically used RSS as the "first draft" for their service, etc) but not in the big way most geeks thought it would. Commercial and user interests did not align with a vision of complete openness where standardized feeds get pushed from machine to machine, moving free and public content everywhere. Also, most services found the format to be a straight-jacket, and once you start adding custom namespaces, you might as well just use your own format. It fit well only for periodically-updated news/blog sites, which is what it was built for. And its worst sin is that it's fundamentally a one-way technology, a broadcasting tool, not a bi-directional tool. Social tools can be built on top of it, but at that point it becomes just another messaging format, and not particularly efficient either.

RSS will survive in some form (like RDF, remember that?) but will never gain widespread popularity, unless it's somehow reinvented in a way that will align with the interests of big commercial players and/or large number of users -- something we failed to do in the last 10+ years.
Since a crash can happen at literally any time while driving, and the bill requires data to be recorded before a crash, I suspect "reasonable" would be "any time the vehicle is turned on." I guess it depends, then, on how loosely you define "crash."
4. Surround yourself with friends who will remind you
you’re awesome when you need it & shit on you when it’s
time.

I hate it when my friends go out of their way to say nice things about my work. They do that because they know much effort I put into my work, and they don't want to make me feel bad.

But this is counter-productive. You're not helping me if you don't point out what can be improved!
I guess we have Credit Suisse, Morgan Stanley, JPMorgan, and and BofA to thank for under-pricing this by nearly 50% [1]

[1] http://www.sec.gov/Archives/edgar/data/1353283/0001047469120...
Google now provides an airline reservation system
New York Sues Sprint for $300 Million in Tax Fraud
How to crash the paid search world
You are right that the decline is social, but it's not because "they" want anything. RSS was never a technology that managed to catch on outside the uber-geek crowd. I use "uber-geek" intentionally because it seems to me that most tech-savvy people I know don't use feed readers (in their browsers or otherwise).
Ok dude I just voted for you on http://about.me/ericjamesjohnson. Good Luck!
Linux Tracing for power users and developers
You could conceivably use the data to protect yourself against false claims in the event of an accident ("he was going too fast when I pulled out").
Indeed - nice to see some numbers, I guess this is the advantage of the P in IPO...
I think the biggest problem with RSS is that you divorce the content from the context. Both from the publisher's standpoint, when their ads aren't being served or they decide to truncate their RSS feed so they can get ad revenue back from click-through, and from the reader's standpoint, where a common lamentation in moving to RSS is that you no longer get to read the original site regularly.

I solved the "Original site" problem by building the original site into NewsBlur -- http://www.newsblur.com.

The other big issue with RSS is that there are too many stories with a low signal-to-noise ratio. I built in filtering and highlighting into NewsBlur to address that concern. And it's a completely separate backend from Google Reader.

And now the common refrain is that people use social channels (Twitter/FB/Tumblr) to find links and news. So I just built that into NewsBlur with shared stories. You can sign up to be a part of the private beta at http://dev.newsblur.com. I'll send out invites to anybody who signs up.

Consuming the web through RSS can be problematic for both publishers and readers. I'm addressing the big three issues - context, relevancy, and surfacing - with a strong commitment to both readers and publishers. Let me know what else you would expect to see in your ideal reading setup, and chances are, RSS offers the foundation to build it.
Just have a look at their source ;-)
http://www.drople.com/index.html?&fb_source=timeline
Pushing through my own cynicism here, you can't ignore the fact that there is added value to the consumer if she/he is a defensive driver. In the event of an accident, there is significantly more data for the insurance companies to use to determine fault and liability.
What Android app you use for hacking? 
i would like to vote.
FaceNiff
DroidSheep
Overlook Fing
Shark
Am I the only one who thinks PinFace is a better name?
Review my project......bakarBox...what else can it be used for..
I am in great dilemma..I have created bakarBox with the aim to share your wtf moments...
But I guess the design/site can be used for other things like discussion forum...etc...

So friends i want to have your opinions for what else can it be....

http://www.bakarbox.com
Ask HN: Which startups have nice/normal hours?
Well done. One more way to realize everyone in my social circle is boring, but well done.
http://cappuccino.org/ - Javascript and objective-j. It's not a library, but a framework.
The supreme court decided it was unconstitutional when does as an unsupervised action of the executive branch. The action is in principle legal, but requires a warrant. The warrant is a check vs. a different branch of government. This is a law passed by the legislature, so that analysis doesn't hold. As long as the executive branch stays inside the boundaries set by the law, the checks are in place.

That doesn't mean that it's clearly constitutional either, just that the basis for the court decision isn't applicable here.
Why do you care? A picture of cleavage is just as valid as a picture of anything else.
At the end of the article ExtremeTech fails to list one of the key beneficiaries of certification:

Sysadmins without 'buying power' who are already running Linux on corporate infrastructure and who are taking flak from PHB management.

(Coming from someone who stood aghast at the purchase of $5k per unit of vulnerable-by-default Windows Server based SSH servers when two Pentium IIIs from 1998 running Ubuntu LTS would have worked better - to handle 100MB of data three times/day on a 10Mbit synchronous cxn.)
RSS dead? The best RSS Readers For The iPad
Andy Ihnatko about Oatmeal about difficulty of watching Game of Thrones: http://ihnatko.com/2012/02/20/heavy-hangs-the-bandwidth-that...
Do IT Execs Make Too Much Money?
The typoed syntax was nicer than the real syntax, unfortunately.
It would be more correct to say - the huge amount of power required to accelerate all the fuel + rocket + payload to high speed at the start.

If you could fly up to orbit at walking pace and then boost the horizontal velocity to orbit you would need very little fuel - compared to firing a big rocket for a few minutes so that the huge mass can then coast to orbital heights.
Contents of the article aside, techdirt regularly writes fantastic headlines. I wonder if it's just the individual authors having a flair for the zinger, or if they have an editor who spruces them up before posting.
I worked at Amazon for several years; one of my team's biggest projects during all those years was expanding certain partner programs to new international locales.

I think Amazon generally prefers to launch quickly in one or two big locales, then expand geographically over time. The alternative is to delay the launch everywhere until support for every region is ready. Launching everywhere at once has its benefits (in particular it can make for better publicity), but potentially at the cost of being later to market and the opportunity cost of revenue not earned during the delay. Amazon has less focus on major PR events than Apple, so it probably weighs these costs and benefits differently.
The word "exploit" is a synonym for "use". It's only recently that it acquired the negative connotation of "use without consent or compensation". If the quoted commitee member (it's not a quote from Torvalds) isn't a native English speaker, it's a reasonable mistake to make.
"the primary function of the black box devices would be to record..."

Ok.

"...and transmit data"

Wait, what?

Are there any further details on how this is supposedly going to work? Do the boxes have built-in cellular modems with permanently-activated SIMs? What network are they connecting to? Where are they transmitting the data? Who maintains the servers?

Transmitting black-box data is a huge leap beyond simply recording it.
Paging the author of Alamut...
Nice. Thanks Jeremy.
If I were implementing one of these black boxes, I'd interpret "reasonable" in a privacy-preserving way: use a ring buffer that stores, say, 4 minutes of data, and stop recording 2 minutes after a crash is detected. That should provide enough data about the crash without being useful to someone who wants to spy on the driver.
Fully Bayesian uncertainty measures -- as a service
FriendFeed put a nice UI on it. The site is still running, although not actively maintained.
If those rewriting rules have to be server-side, and I think that's what you mean, the answer to that is that browsers don't get to dictate terms to servers that way; browsers can say what they will and won't accept, especially in terms of content type, but URI format isn't generally something the browser can specify.
I've seen quite a few startups with "normal" (say, 60 hours or less per week) hours. That being said, the people I know who put in 100+ hours per week on their startup also have been more successful (long-lived company, multiple millions in revenue per year, etc.).

I think it's possible to have a startup that promotes a sustainable lifestyle, but it's all about costs and benefits. If you work 100+ hours per week, you might miss out on seeing your kids grow up (or having any in the first place). Working ~50 hours instead might make your business grow more slowly but might allow you to enjoy other (more important, for some) aspects of life.

As a side note: some of the investors I've talked to also encourage and prefer a more sustainable lifestyle in a startup. That way you'll be alive in the long run. :)

I don't want to name any names or give explicit examples here, but happy to discuss you're making a difficult decision.
YOGURT DELIZIOSO IN BALLON
No, the primary purpose of these is to determine the events that lead up to an accident. The penalty is because the only people with an economic incentive to remove the boxes are the ones likely to cause accidents.
The thing that bothers me most about this is I credit HBO for leading the charge with innovative content that as a whole brought TV to a much higher level. They took big chances even when it wasn't profitable to do so.

I've had a serious love affair with the network beginning with Dream On, The Larry Sanders Show, then moving on to Oz (yeah it was a 'male' soap opera I guess :), Sopranos, 6 Feet Under, Deadwood - which I didn't particularly _love_, but highly respected, and most of all The Wire (best thing to ever grace the screen IMO - they lost $$ on it throughout its run)... and then I killed my cable sub and haven't seen anything of their's since.

Now Mad Men and Breaking Bad are my two favorite shows, they're both on AMC, and I can easily purchase each season on iTunes HD for just north of $30. Every episode is available hours after they originally air. I'd pay twice that much.

Of course, the problem is HBO is just too tightly coupled to big cable. They're one of the main attractions, and as such the kickbacks they get are tied to contracts that prevent them from wresting their content to any great degree. Until this model changes, their A content won't see the light of day, and more draconian measures are likely to be put in place to thwart piracy. It's not HBO itself per-see, but HBO as a proxy for big cable; as a defense mechanism to prop up a flailing business model.
>A GCHQ mathematician said the fact that the contents had been restricted "shows what a tremendous importance it has in the foundations of our subject".

It probably shows that nobody with the authority to clear them for release understood them and it was safer/easier to just stamp restricted and let somebody else worry about it in another 30years than admit it.

It's pretty much a safe bet that, even within GCHQ, anybody with any seniority in the British civil service will have no technical background.
"Is accuracy important?" and other questions in enterprise analytics
This works until you have any major medical problem. In the past, people would just die.
Mac OS X invulnerability to malware is a myth, says security firm
Thanks for your reply. I really appreciate it.

Good points. For the band generator, you're right: I had also in mind one-off trysts:) Regarding the drums on the collaborative online recording: I was more thinking something that could be generated from a MIDI keyboard. I have been playing drums for several years and always got frustrated by the challenge of recording a neat drum sound.

Congrats with what you've build so far. Keep rocking with Fandalism.
The subcomment by jen_h has the best information in this thread.

http://news.ycombinator.com/item?id=3863555

The submitted article is just passing on the content of an Infowars post

http://www.infowars.com/mandatory-big-brother-black-boxes-in...

but the true primary source for this story is one of the United States federal government sources, for example

http://www.govtrack.us/congress/bills/112/s1813/text

with the text of the legislation.
Rails One Click
Plane landing aborted at 392 feet as pilot is too busy texting
On Buffer Overrun Vulnerabilities, Exploits and Attacks
Black-box recorders exist that store data onto an SD card in a constant loop. History depends on the available capacity - around 1 day for a 16GB card. When an accident-event is detected (sudden acceleration or deceleration) the device permanently stores 1 minute either side of the event.

http://www.roadhawk.co.uk/
This is the first I'm hearing of Newsblur. I've contemplated building something similar to try and tackle some of the issues I raised in my comment in this thread. Looks like you're well on your way.
Er, did the app store actually do that? I thought there were still countries with no app store.
This is the first I'm hearing of Newsblur. I've contemplated building something similar to try and tackle some of the issues I raised in my comment in this thread. Looks like you're well on your way. I hope you stick with it! I'd really like to more out of RSS.
Think of it as passive opposition, i.e. failure to do something about a cause.
I am happy to see courses in the humanities. The Greek and Roman Mythology course looks like fun.
Interesting, especially given the rails.app kickstarter project (http://www.kickstarter.com/projects/1397300529/railsapp/post...)
Cars kill 30,000-40,000 people per year in America. They're 4000 pound killing machines. If this actually happened it would be a good thing.
Cheap Terahertz Camera
Skills That Pay the Bills: Top Maker Schools
They already do this on a voluntary basis:

http://www.bbc.co.uk/news/technology-16969509

Makes it a lot cheaper for young drivers to get insurance.
Ditto for finding the browser implementations useless. I did use Thunderbird for years, though.

The irony is that I'm now using GoogleReader in a browser on my smartphone (Android) to read RSS feeds. I still have some feeds into my Thunderbird configuration, but mostly ignore them there.

I tried the Google RSS feed reader app (Android) and didn't like it. I have not tried other RSS apps, the web-based GoogleReader meets my needs (I have a personal policy to minimize the number of install apps).
Free Sweet Games - Игры на раздевание + 300 дeвyшeк
I agree mostly with your post but there are computational approaches being developed that may help improve our understanding of these cancer networks.

They will in no way eliminates or reduce the need for wet lab biology but hopefully it will couple with improvements in high throughput experimental technology to help us design and make sense of experiments targeted at understanding the whole phenomena.
He's never going to be a paying customer anyways.

before torrents he'd just show up at some friend with hbo. Today people don't mingle irl, so he downloads.

People on 4Chan age group are found of watching streaming with chat on the side. It's pretty much the same shinding concept of yesterday.
I believe that, based on my own non-scientific observation, most non-technical people don't really know what RSS is or what it is used for.

I think that YACG, AutoBlogs, and so forth have also made website owners question the value of publishing RSS feeds as well.

Personally though, as someone who has launched several niche blogs over the years I find publishing an RSS feed to most of the big feed directories to be the best way to get a ton of backlinks to a new sit in a very short amount of time.

Of course large established sites have no need of this "benefit" so they largely view RSS as brand-dilution factor, not a brand-promotion factor.
Uber Takes on Cabs, Setting the Stage for a Future Clash
Oh man, I wish I had noticed the "Infowars" cite before I upvoted this.
"We've recently discussed the fact that HBO severely limits the availability of its shows to non-subscribers..."

Really?! How dare they!
Study Explores Electrical Stimulation to Aid Memory
Well, it's also entirely open-source, from the front-end to the distributed feed fetchers on the backend, as well as the iOS app: http://github.com/samuelclay
Is that really screwing their customers? They license by GB/day usage. As expensive as Splunk is, an audit if they think you're really underreporting usage doesn't seem too far fetched.