skysight-inc/HackerNews huggingface dataset:
I can't read the article but there's no explanation for why they would be interested in isoleucine in particular. They also seem nonplussed as to the mechanisms of any isoleucine-restriction longevity. As a result it comes across very post hoc.

I suspect I'm missing something though?
Finally, some good tumor news, but, also, is that blood I just spit up?
Paradoxically, I was lucky enough to work with something I love, music, for 7 years.

Just as the internet and social media helped me gain enough exposure to make a living DJing and producing music, providing a decent life for my family, the intense competition for attention on social media, exacerbated by the pandemic, made continuing in this profession unfeasible, largely due to my somewhat introverted personality. Bandcamp wasn't really my thing but I had some friends that made a decent money out of it.

Anyway, I wish the best of luck to those still trying to make a living from music in this new era.

I'm unhappy with my current job, but at least I can pay the bills.
This is great to hear. That book made me feel secure about enjoying baseball on the radio and opera season.
> There is no limitation in copying the work of an author for personal enjoyment without permission.

Actually there is in many jurisdictions of the world, including mine (France). There are some exceptions enshrined in copyright law, for which we actually pay a tax.

But this is besides the point. It's not even about the personal copies you make from your legally-obtained original copy on the first place. It's about where you obtained that initial copy from. Most definitely not legally from the author, if he is not authorizing RE.

> Reverse engineering might violate other agreements but not copyright law.

What other agreements does it violate? It is copyright law the only thing that puts a restriction between you and doing whatever the fsck you want with that code. There is a reason the RE exceptions are enshrined in copyright law...
And? That’s not why Netflix gave him the money. They could have done that themselves.
They offer educational content. From limited consumption I would not rate it as high quality. More like acceptable I guess.
I think you are right.

We will be squeezed step by step. Sad but it's going to happen.

I am still not premium subscriber, but something weird has been happening to me, whenever I click on want to watch older videos like 6-7 yrs old, it loads slower, also on such type of video, I always get grammarly ads. If I guess correctly it happens for around 20 sec then I see skip button.

I'm still using chrome browser.
I agree with everything in that post the problem i have when i even try to get someone to use alpine which is still a full OS just small is that no one cares. Developers don’t care that they have a 3GB image. They don’t want to learn about any of it. Ever time a developer has an issue with docker it comes right to the infra team like we own the image that they completely wrote and now is broken because they pinned it to latest.

We are in the nodejs world now where speed is all that matters. No one wants to understand what is going on under the hood. And no one takes the time to learn something new when your job only cares about the next feature. At the end of the day all that matters is money.
It's components plugged into sockets as opposed to soldered into the board.
Because we desperately need more aggregated garbage clogging the information highway.
2011 was a large scale snowstorm in Texas resulting in rolling blackouts for 5 days. It was very slightly less severe which meant people got power restored in the middle of it thus mitigating most issues, but 2021 only happened because they didn’t actually fix any of the issues revealed in 2021.

https://www.nerc.com/pa/rrm/ea/Pages/February-2011-Southwest...
This was a brilliant read for me back in the day (still is!) and gave me the inspiration to write a post[0] about detail abstraction, market forces and why you can't fit big cups in coffee machines.

[0]: https://omarkama.li/blog/the-market-decides-your-project-sco...
Same as it ever was. The “proles” want to be entertained not made to think - this is an observation that dates back a long time.
Did you honestly just make this a comment about carless cities? That we can't fight anxiety without having carless cities? Seriously? People really are just completely stuck in echo chamber cults at this point.
I'd like to avoid having to convert it all the time (e.g. MacOS' music player doesn't seem to support that? But gonna have to check it). And the sizes are just enormous.

But yeah, as storage space & bandwidth are less and less an issue, if FLAC is fully supported across the board, the scale should be tipped. My worry comes from we not quite being there yet.
You can also find artists that do live streams and directly pay them.

Buy merch, see shows, etc.
I've always liked minimal straightforward editors over IDEs. I used BBEdit on Mac OS and Notepad++ now on Windows. And vim wherever relevant. Thank you, Notepad++ guy.
There is more:

> A correction was made on Nov. 22, 2023 : An earlier version of this article misstated the status of Carl Erik Rinsch’s series when Netflix bought the rights to it. There was a script, but it was not complete."

'is not complete' can mean many things.

Also Netflix initially planned more than one season, but then they backtracked when the script was extending beyond the first season - there seems to be a gap in the narrative of the article.

> Netflix gave Mr. Rinsch final cut, a privilege it had previously bestowed on only a few directors. And it assured Mr. Rinsch and Ms. Rosés that they would remain “locked for life” to all subsequent seasons and spinoffs

vs

> Mr. Rinsch had missed several production milestones and was toggling between two versions of the script, a shorter one that matched the original 13-episode plan and one twice as long that would have required greenlighting a second season.

Also 'missed several production milestones' is a bit vague. That year we had Corona, which would naturally lead to some sort of delays.
Fair question. This is where I’m struggling and part of the reason I ask the question.

On some things, it’s likely I neither have a chance nor would they want me interfering. I respect that.

On others, it’s clear they want help or would accept it, but don’t have the time, energy, or inclination to do it themselves. I specifically asked about several of my ideas — they’d both accept help cleaning/decluttering, and my dad would be happy with a meal service if he likes the food (he treats my mom like one, sadly).

My family didn’t grow up with traditionally strong emotional ties and I think we all wish we were a bit closer. I get what you’re saying but I’m not sure it’s letting go so much as seeing where they struggle and trying to help. My mom does actively ask for tech help, ironically, running websites with some online sales etc. She’s not great at finding solutions to help herself, or following through when she knows they’re useful (struggled to install a dash cam she bought which was basically “plug into car charger and go”).
If what you're saying is correct (the parts were purchased as spares) then that is actually fraud.
Card testing doesn’t require a purchase, fraudsters can validate a card by adding it to an online wallet. The retailer will send a $0 authorization to the bank.

Fraud happens across all transaction amounts, what do you think people use the cards for once they buy or guess a valid card?
...MacOS' music player doesn't support FLAC?

Sometimes I'm just baffled by how broken the Apple ecosystem can seem.
you forgot to mention they did a great job building a hyper optimized 14nm process, spent at least 5 years on it...
Friend of a friend built and ran a very successful restaurant for a decade give or take. Staff was treated and paid well and everyone was happy. Eventually they sold the place because they just didn't want to run it any more and the new owners drove it to shit in all the ways you would expect. They felt bad but what else were they suppose to do if they just didn't want to run it any more? Sometimes the answer isn't money, sometimes the answer is the owner is just tired and wants out.
Trig was already mentioned. It's definitely not the answer to the question GP is asking.
I applied two days ago and havent got any response yet.
I don't believe Scheme as standardized has delimited continuations, only call/cc; it's just that Scheme implementations have often been the laboratories in which experiments on delimited control have been performed.
Generalising an entire racial group is by definition racist.
Yeah but if you're gonna build something, build something useful lol. Who wants an encyclopedia that returns inaccurate stuff? The whole point of an encyclopedia is that it's been reviewed by someone for accuracy
Strange choices.
ESB is in almost every way a much better film than Star Wars.
T2 much better than T1.
Aliens better than Alien.

I haven't seen the other two, bet I'll just assume they also have better sequels.
Eventually idealists get tired of eating dog food or want to retire
Below are quality suggestions

- Red Hat linux
- Blender 3D
- PostgreSQL
- Django
- Ruby on Rails
- SQLite
- Pandoc
- Ffmpeg

Can’t wait to see others’ suggestions.
A failed film generates a write-off whether or not it's released. If released, then the losses (and associated write-offs) are taken over the course of several years, since many of the costs of the movie are treated as capitalized costs that get expensed over time.

If the movie is not released, then the expenses can get written off all at once. Due to the way financial accounting works (e.g. time value of money) an immediate deduction is more valuable than a deduction over time. In this case, the value would have been from offsetting profits from Barbie. It's a small savings, only about 6m in reduced taxes (on an approximate 30m writedown, taking into account that WB did not fully finance the film itself and so losses would be shared with the other investors), for an effective loss to WB of 24m.

Based on the 2x Budget principle (marketing and distribution combined are generally the same as the production budget), with a 70m production budget, Coyote vs Acme was expected to make significantly less than 140m gross if released. Given that they were willing to completely write off the film, this means they were expecting a total box office gross of significantly less than $115 million.
I checked the title, the 28nm and the date of the article.
> what thought process would make you even think that?

The thought process that sees a conspiracy in every single thing that’s happening in the world today.
I love the API and response times! I had a few questions:

Might you open-source this in the future?

Were you already comfortable in Rust or is there a reason you selected Rust for this project i.e performance and so plans to offer this as commercial product?

How often are RIPE info and MaxMind data updated these days or is that the 8 hours?

Thanks for sharing!
For those both unfamiliar with Menzi Muck walking excavators and having a little boy's love of construction equipment, there are plenty of videos online of non-autonomous skilled operators with fancy moves...
Show HN: Simple NYC Geo Guesser
Me & my wife moved to NYC recently, so I quickly made this simple game to learn how to navigate NYC grid system. :)
Run a security scanner against that 3 GB image and tell the devs they have 1,000 CVEs to fix before they can deploy.
Are you serious? A ton of people will just take anything for free that isn’t nailed down.
The whole docker/container craze was supposed to fix "works for me".
Vinyl won't get the most to the artist per dollar spent though. Most of the revenue from vinyl goes to people involved in the production and distribution of the physical record.
Except that in this case your backups might have already been corrupted... because the first version of the file was already messed up.
In the original article, he suppose that nuclear plants are on the rise due to climate change policies, so maybe there will be a demand for gamma ray sensing in environment, to monitor leakage...
The idea I extrapolate from his work is that you can plant its potatoes around the plant and control it from a reasonable distance with fluorescent sensors, in relatively large areas. Or put some potatoes in officies and see if it start to glow.

The complete article: https://onlinelibrary.wiley.com/doi/full/10.1111/pbi.14072
From your comments, I think I understand why the "choose an octave" thing was such a hard choice, but I think what you settled on was quite possibly the least intuitive option for me. Even once I thought I understood how it worked, it kept jumping around on me every time I wanted to try another note. It was frustrating enough that I wouldn't come back to the game over it, because I can't even practice with it until I do get the hang of it with the "one puzzle a day" limitation. And most of the comments support that it wasn't intuitive for the majority of people.

Virtually everyone has at least some relative pitch, enough to know "the next note should be right/left of the last one." Moving the whole octave, and only really showing that with the highlights on a tiny keyboard above is just confusing.

I'm one of those people who virtually never puts my phone in landscape mode, but I would rather unlock landscape mode for one puzzle a day so you could display the full range of applicable keys for the featured section of the song than try it the current way again.
This rant is all well and good, but the folks who really need to hear this are the sales and marketing folks at the third-party software vendors who happily burble that “we’re containerizing/containerized!”. Then you peer into their implementation only to find out they popped a VM into that sucker and called it a day. When you get on a call with them, you find out really containerizing their product (of which “distroless” is only one of many, many re-architecting and re-designing their product should go through) is nowhere on their roadmaps, because too few customers are demanding it.

We might need a “X Factors” list to popularize what checkboxes properly “containerized” products should tick, to help move the needle.
gcc -E
Why not unikernels?
Can you estimate what proportion of fraud is automated/bot/scripted versus manual human interaction? Do you rely much on botnet detection or IP reputation?
Great piece by John Carreyrou, who broke the Theranos story and wrote the unbelievably entertaining Bad Blood. I wouldn’t be surprised if this story is his next book.
What the heck lol. My CS capstone project over a decade ago was a cross-platform app called “Columns and Rows.” Won some prizes from nVidia and Microsoft, with the exact same premise as OP. Written in Backbone.js though.
I wonder how many decades before someone hooks this up to a webcam and lets people play minecraft in real life.
Humanity just very short time have instruments to hear sky.

Visual observations exists much longer, but they are limited to just our galaxy, Milky way (more distant sources are not bright enough to see them with naked eye).

And even most obvious mask ideas (and development), which we see on our current sci-tech stages, very fast move spectrum to infrared, which is near impossible to observe via thin atmosphere. And even now, I hear about developments of laser cooling, which could emit extreme amounts of heat into some direction, where nobody will see it.

For example, now Earth communications conversed to Ultra high frequencies and very high gain antennas (3G, 4G, 5G, emit only very narrow beam to receiver and are very short range), and to fiber-optic communications, which emit just infrared from heat. Also, Ultra high frequencies very quickly absorbed by moisture, so also effectively converted to heat infrared.

So, right question should be, how much time industrial civilization emit observable to others emissions.

And imagine, what could alien civilization learn about Earth from locations, where clouds are rare, as others they could not hear :)
I mean enormous compared to an MP3 I guess but I have 19,000 FLAC tracks that takes up less than 500GB, pretty cheap to store that in 2023.
There is no universe in which I "mail checks" (sic) to anyone. I wouldn't even know how to obtain a chequebook, I doubt my bank issues them. It's not 1995 anymore.
Will weight-loss drugs put diet charlatans out of business? I hope so
sure but not every artist offers this and its much harder to find the individual channels vs having one big index.

But if worst comes to worst that will be the alternative for the time being I guess
Strong obesity medication now available, if you can get it
There's always a wavery, indefinite line between 'cribbing from un-cited sources' and 'everybody should get that reference.' I'd assume the article's on the latter side of the divide, but still worth mentioning (as you've done) for people who don't read this stuff all the time.
Pydantic is all you need [video]
Qobuz has a good web store full of full-res releases, but it's more oriented towards label releases. Bandcamp is still superior when it comes to brand new indie releases. Hopefully someone will fill the vacuum if Bandcamp goes away.

https://www.qobuz.com/us-en/discover
love this, nice work :) so fast.
Wild-assed guess: the benefits of increased muscle mass and bone density matter much more to humans than they do to mice. We are large and heavy, while mice are small and light.
If this comment is the best LLMs can do then really we have nothing to worry about
One of the best self hosted mail services I've even used. Automated setup for caldav/carddav adds the cherry on top
nobody can tell you what it is like to be a crab ... yet
> Most PC and console games people play have gatcha mechanics

I work in the games industry, and this just isn’t true.

Where are you getting your information from?
> Will this be open-sourced?

I don't think there's a strong reason to keep it closed-source.

> Were you already comfortable in Rust or is there a reason you selected Rust for this project?

This was a big learning opportunity for me to learn Rust. I had done two small projects in Rust before this one.

> How often are RIPE info and MaxMind data updated these days?

The MRT dumps where it gets its BGP data are updated every 8 hours, and MaxMind appears to be updated twice a week.
Haha, those two devices are so different it's not really a useful comparison. One is a sampling groovebox, the other is a sampler module. Use Cases are also totally different. If you want a cheap sampling groovebox with a thoughtful workflow, portable, mic, speaker, battery operated, fun to play with there aren't all that many choices other than maybe the Korg Volca Samples. It's around 3x the price, but it easily has 3x the functionality.
they are good true.
but I always wondered if they pay artist as well as Bandcamp does.
There is probably some info online but it seemed to me that artists do prefer bandcamp, so I figured they get a better deal there
Way above my head but less of whatever isoleucine is doesn't sound advisable:

https://aminoacidsguide.com/Ile.html

"Isoleucine participates in hemoglobin synthesis, as well as in the regulation of blood sugar and energy levels. Studies revealed that this amino acid has a very low toxicity at pharmatological levels up to 8% of solution concentration in rats."

"As a matter of fact, the three amino acids (Isoleucine, Leucine, and Valine) constitute nearly 70% of all the amino acids in the body's proteins. That is why their value in human body is so high."
Then you can start layering on the complexity by estimating repayments based on the expected variability of future interest rates, convert to Real Dollars based on inflation and expected wage growth, then compare with alternative options such as renting + investing, etc...
Many of the physical adaptations critters on this planet have made were in response to evolutionary pressure. Eat or die. Reproduce or your bloodline dies. Get those resources before something else does or die.

At the moment AI doesn’t really face these pressures. They don’t need to get better at “getting electricity” - something else does that for the AI systems so there is no pressure to “be aware of where your next electron comes from” so why waste the processing ability to track such things?

I guess what I’m getting at is consciousness seems like an emergent behavior of keeping one’s self alive. Maybe if we start threatening AI models then consciousness will emerge?
> was able to solve basic maths problems it had not seen before

That's the thing. ChatGPT is interesting, but if it can find more precise associations than "the second best token", that's worrysome for a lot of digital jobs and jobs that can be replaced by robots.
Yes, it has an invisible "shadow prompt" that gets sent to it when you start a session. It looks something like this:

https://www.reddit.com/r/ChatGPT/comments/zo9of4/comment/j0n...
Making more back doesn't really change the misappropriation. Martin Shkreli went to prison for doing effectively the same exact thing.
Interestingly though, the article says mice on the low-isoleucine diet did better on muscle strength.
Sympathies. I've got some similar challenges with my Mom; and a lot of history in the way.
Foxconn founder Terry Gou drops out of Taiwanese presidential race
This is how everyone works everywhere. The accountant doesn’t want to learn how windows services work, they just want to do their work. The c level obviously doesn’t care how anything works, they just want their data. Expecting people to care about things outside of their domain is a losing battle. Better to focus on taking the part that isnt their domain out of their hands so better choices can be made.
A sister comment to mine gives you one strategy, but you can also use the first stringer as a template to the rest.
OK so to translate those 'consciousness markers':

- You've gotta have a brain like ours

- Messing with your brain should do the same thing to you that it does to us

- Gotta have 'attentiveness' since the homunculus needs a homunculus too

- It's you in the mirror

- Get wasted like us

Hmmmyeah these seem like good yardsticks for consciousness. /s
Apparently it wasn't an issue? The article says mice on the low-isoleucine diet did better on muscle strength.
Nice, I used to play "Melodle" (https://melodle.yesmeno.com/) which seems very similar, but I like that this uses real songs.

I think it would be great to have an option that disables playing the pitch that I select, as for me the pitch removes most of the challenge.
Without reading the article and just from my own anecdata, pretty much everyone I know would rather use cannabis than any kind of pain med stronger than acetaminophen. I would say from the people that I know, the side effects are much more of a concern than procurement.
Isn't that just basic radio engineering? What does C have to do with radios?