Of course, and much love! Pyruvate is fantastic too, and w/ niacinamide if you're going for the nicotinamide riboside route don't forget to try taking ribose with it -- it apparently _really_ makes the difference for some!

So much mitochondrial implication in any post-viral fatigue syndrome, it seems like somewhere in the stack is oftentimes disrupted, thankfully it can be managed though!

Night and day for me. On the Appalachian Trail, I had to count steps and watch my heartrate on the climbs to keep from triggering PEMS (you don't want that out in the semi-wilderness). I had extra food and would take days off when I did trigger PEMS/go mildly hypoxic/lactic acidosis, whatever. Not fun, but boy was it a pristine place to take break days, in the perfectly gorgeous wilds (surrounded by interesting and talkative, friendly people. heaven).

In any case, on the AT it took so much discipline. I switched to keto after getting norovirus because why not on the momentum of not eating for several days, and some of the ridge runners helped me out as well (they are true trail angels I think). The keto really softened my PEMS a lot, I think basically by preventing the lactic acidosis spiral because...yay, no glycogen in the energy cycle anymore. That was my motivation/thought at least, and it did really pay off, it seems (for whatever reason!).

Pyruvate was my second best shot, it would really reverse a lot of problems to a manageable degree so I could do more basic stuff and focus on rest days, etc.

Eliminating free glutamates was _huge_ for me. Maybe not for everyone, but for me, absolutely. This is yeast extract, miso, soy sauce, hydrolyzed corn protein, anything that is umami basically is glutamate or glutamate-related in some form or fashion. For whatever reason, blood glutamate scavengers seem to be well-implicated in reducing symptoms of me/cfs quite well (and fatigue in general? i think?), this is not quite as well-known as I think it should be, but check the research out on that for yourself!

I'd have energy crashes after having, say, beef jerky (which already has glutamate, just competing with the other amino acids during breakdown), which often has tons of soy sauce or the like. Everything seemingly has MSG (or the equivalent), though they can legally lie if they put it in via a different source, apparently.

(Don't get me wrong, I love MSG. But it can make the lives of me and other people with fatigue stuff absolute freaking hell).

All that to say, niacinamide sorta waltzed up and smashed the delicate glass wall that I'd been balancing things around. I'm very grateful for it, it sorta feels like easy mode (minus all of the symptoms lol) compared to the other stuff.

Please feel free to ping me on twitter if you ever want to! <3 :'))))) Happy to chat further about this, and much love! Thank you so very much for your encouraging words, ME/CFS, long covid, post viral stuff is a hellhole of a syndrome as it basically feels like it sucks your soul out of you physically (experientially, at least, lol), and leaves you dead-alive. There is hope, and much CFS does not last forever! And even if it is there, I can assure you that there is a way to enjoy and love life, it just becomes much more of an inward and spiritual (if necessary regardless of the requiring circumstances) journey.

Sorry, that was a lot, I, er, maybe am recalibrating to my energy levels. Also, I'm very passionate about this particular topic! <3 :')))) :'))))) :'))))) :')))) <3