skysight-inc/HackerNews huggingface dataset:
It makes sense to me. I once read a lung cell has to evade seven different anti-cancer mechanisms to become a malignant stem. If there are ten different ways to get around each defense, that would mean ten million different possible configurations of lung cancer, with all the therapeutic headaches that implies.

Edit: And that's just for one cell type out of the myriad that compose a functioning lung.
It is good to have an end to journey toward; but it is the journey that matters, in the end

-Ursula K. LeGuin
Positing that Facebook purchased Instagram for its architecture strikes me as odd. They (FB) have solved all of the problems that Instragram faces and more for a userbase roughly twenty times as large, and while the infrastructure is interesting for those at companies aspiring to Instagram's success, for your average systems engineer at Facebook or Google I would think it seems pedestrian in comparison
Great article, I just hope that Brian is able to reply the oppositions response posted.
Just so you don't feel like you have to apologize for your self, preventing you from sharing your work at whatever price you feel fair isn't borderline price fixing -- it is absolutely price fixing.
Gun laws are only stupid in America because we have a Constitutional right to them. If the laws didn't get challenged based on their constitutionality, they'd be a lot more sane because they'd be a lot more broad.
Without him, the world would be a different place. The Commodore computers inspired so many people (adults now) and made all "our" business world, start-up world and hacker world what it is now. By bringing home computers to a huge number of houses, a lot of kids got the chance to experience first-hand what it is like to be in control of a "personal" computer.

There is still a C64 scene alive! http://noname.c64.org/csdb/
> Exactly what "liability" were you thinking of here?

(3) EXEMPTION FROM LIABILITY- No civil or criminal cause of action shall lie or be maintained in Federal or State court against a protected entity, self-protected entity, cybersecurity provider, or an officer, employee, or agent of a protected entity, self-protected entity, or cybersecurity provider, acting in good faith--

(A) for using cybersecurity systems or sharing information in accordance with this section; or

‘(B) for not acting on information obtained or shared in accordance with this section.

===========

Part (B) is pretty troubling. Suppose they find out, due to information shared in accordance with that section, that they're compromised. In spite of this, they fail to protect your money or data. Are they covered by that?
This is much more likely to be about the VPPA, a law which Netflix believes makes it illegal to provide social
features in the US:

http://www.hackingnetflix.com/2012/01/netflix-to-testify-tue...
s/cuple/couple/

(sorry!)
While I agree with you in principle, I think that in the long term, piracy issues in the United States are going to go the way of abortion.

Just to illustrate what I mean: I personally oppose women's right to have abortions -- no holds barred -- I think that it's always morally wrong to pursue the termination of pregnancy as an end and practically always wrong to pursue it as a means to some other end (although there are cancer treatments etc that jeopardize the well-being of a fetus that people should not be barred from pursuing simply based on the potential harm).

On the other hand, it is very clearly a cultural issue. I believe that on a practical level, to attempt to police abortion would require a Stasi amount of government effort. If the people want the right to abort, the horse is already out of the barn, and the job is not the government's to swing the pendulum back, it belongs to magazine article writers, philosophers, and op-ed journalists. If they should fail, that's okay. It is more important not to live The Lives of Others than to save those children's lives, simply because saving them would not represent a noble Arthurian quest, it would involve spying on pregnant women and assassinating doctors. Disgusting.

Intellectual property is a patently less important arena of human activity, but I think in a similar way the policing of the internet should be cultural. There ought to be a cultural directive not to steal things over the internet when you're not a college kid anymore. When you can afford something, and it's reasonably available, I think this cultural directive already exists.

This cultural approach is successful and that's the reason that -- for the most part -- torrenting and music sales are weakly correlated. Most of the people that think it's okay to steal things, would not be customers anyhow.

I believe that most of the time torrenting represents charity on the part of movie studios and textbook publishers and music labels, providing their wares to those who would not have otherwise been able to afford them, which is not a bad thing, they're hiring cheap brand ambassadors. The ability to work subtle complicated questions like this one out is the power of cultural motivation.

TL;DR : When you're talking about the decision to terminate a pregnancy, or the decision to commit online piracy, the power is entirely in the hands of the citizen. It is so easy to pirate, it is so distasteful to set a woman's body against her will. Law-abidingness in these cases requires the cooperation of the potential "criminals". You cannot pursue justice in these cases through traditional law enforcement.
Scheduling Startup Reflects on Being Acquired by Groupon
This sounds somewhat similar to (software) transactional memory.
I disagree with almost all of that.

It's not a technology business? Is airbnb? You need a way to connect folks who are willing to board dogs with those who need boarding. How do you do that without technology? The bulletin board at your supermarket isn't going to make it happen.

It may not be particularly novel technology, but that sure as hell doesn't matter.

first mover advantage: I personally have no idea if any other options exist for this. I have no idea if they are a first mover in crowd-source kenneling options. It certainly doesn't matter. We've beat this topic to death in the startup community, first mover advantage is rarely an advantage in the first place.

without a bubble it would not get $3 million: Says who? Since I see no real signs of a bubble (in the traditional sense), I certainly don't agree. It's a relatively small amount of money for a business that is taking on a big market opportunity.

A bubble is not the presence of investment in the first place. It's not even the presence of a lot of investment. Bubbles form when investments (on a large scale) are shoved into increasingly irrational businesses or investment vehicles in order to cash-in on the perceived momentum of a space. When you're investing just because "startups are the place to be right now" then you're looking at a bubble.

Here we're talking about a company with a solid (proven) idea, in a big space, taking on a modest amount of money. I don't see the problem.
Twitter open sources its MySQL secret sauce
It's a simple A/B test. They're seeing which social network is the most popular by how many clicks its button gets, even with the page itself being hosted on Google.

;)
No mention of Erlang?
The source is Russia Today. Which, objectively, has an extremely poor track record of reporting things that turn out to be true.

Maybe the featured story on mind control weapons that are about to turn us all into zombies that's there today will change people's minds?

Or maybe we do want to discard troll stories from here and The Weekly World News since they aren't opinions but just link bait.
Well oil is non-conductive, so if there's a layer of oil covering the connectors, there might be a performance impact.
So maybe there is an opportunity for folks like you. You bring your dog with you, and We pick up your dog at your hotel in the morning, care for it while you are sight seeing, and drop it back off in the evening.

Contract out with hotels that allow pets, mostly dealing with small breed dogs, no overnight hassle.

I bet you could use the service from the OP for such a thing, maybe.
Firefox's Jetpack extension API (using JavaScript) is very similar to the commonly used Chrome/Safari ones. You were likely looking at documentation for their C++ extension API.
(1) Modification-prevention (the changing your account to someone else's by modifying the user id situation) is provided by the HMAC, not encryption. This is why Rails session cookies are not encrypted (as far as I know), for example.

(2) If someone has your cookie, they're either already on your connection or they're on your computer.

(3) The only situation where this provides any security is one in which you store data in the cookie that would not be accessible to the same user through the site. I can't think of any such data in any of my experience, but I will absolutely grant that such data may exist.
Well that is, naturally your choice, just as long as you don't try to force this on others.

You see I am pissed that I don't have my flying care and robotic servant already. I want progress and will take whatever stability that is necessary to do that.
No matter if it is 3583 BYTES FREE or 38911 BYTES FREE or some other number - the start-up text was an important message to all users: There's this language (BASIC) available right here at the prompt, ready for you, just type away. And there are N bytes free, available for you to do whatever you want to do.
SEEKING FREELANCER - San Francisco

We are a four man online poker startup (http://kothpoker.com) focusing on heads up (1-on-1) play. We're looking to get into the real money market, which is beginning to become regulated in the United States this year.

At this time we're looking for both a graphic designer and an iOS/front-end developer.

Requirements for front-end stuff:

-Knows how to safely utilize git within a team
-Open-source friendly/proud of your code, shares code on Github or other website that we can check out
-Moderately active within the dev community, has an SO profile
-Proven experience with developing and deploying native (nothing in a UIWebView) iOS applications—can provide links to apps in the store
-Enough server-side experience to be able to investigate and comprehend minor API issues if and when they occur

Requirements for graphic design position:

-A user experience and user interface designer in one—mere graphic designers don't belong making user interfaces. It needs to be a person who can also think in terms of movement and interaction. The equivalent of needing to know jQuery as well for web application UIs.

We're looking to hire someone interested in poker, and initially the compensation would be largely for equity. If you're interested please email jiganti@gmail.com
Mosh: SSH for 2012
> it makes it more likely that people might try to make future transactions directly without using the site

If they make life better for the host, this shouldn't be a problem -- "oh hey sally, glad to hear you and spot are doing well, we'd love to have him stay with us. just go online and you can find all our availability and we'll see your reservation right away. call us back if you have any problems."
3 web ops engineers for 30+ (before android release) million users & 100+ EC2 instances = WOW!
> Isn't piracy illegal?

Illegal is whatever Congress says is illegal. It's not easy to derive an "ought" from an "is". So the fact that X is illegal, on its own, makes no difference when it comes to the question of whether Congress (or anybody else) should combat X. (Pot is illegal in most parts of the U.S., but a lot of people strongly believe that the government should stop trying to combat it.)

It's entirely possible that some subset of X should not be illegal, and therefore Congress should not combat it. I think such sentiments are a major aspect (though not the only aspect) of the debate surrounding SOPA/PIPA. Should it be illegal to post a link to a link to some copyrighted material?

ADDED: I don't think there would be anything crazy or wrong about being against some appropriately defined subset of "piracy", but simply being against "piracy" doesn't seem to be a position that someone who understands all the complexities of the issue can reasonably hold.
And
POKE646,12
so the text color is a medium gray.
Detroit Makes Pitch for Ousted Yahoo Employees
This is an excellent and important point, maybe the most insightful I've read in this thread.

Whatever value Instagram has for Facebook, it probably has at least double that value for Google, who could buy it just as easily. By paying a premium and showing major interest first, Facebook preempted an opportunity for Google to get some traction in the social space. Very smart move.
Meetings.io - Simple, online meetings
A retirement fund for your JavaScript
This is like the argument of "I'd never meet people from the internet in real life". Guess what? Those are real people.

The people you trust with your pets are the same people on rover.com.
Nope - it's not that, though we did come out of a Startup Weekend! (It was the June 2011 one hosted at Amazon's new buildings in South Lake Union.)
The dilution is an interesting point. Why would the founders or Facebook accept dilution (at 50% valuation!) just before an acquisition?
That may be true now, but if the commercial value of these photographs asymptotically approach zero (or close enough for us) then that may be all they are worth -- the choice becomes credit or nothing at all.

And at that time the photographers would properly choose credits over nothing at all.
$1 billion divided by 30 million users = 33.30 dollars.

I had no idea my account was worth that much.
This is an improvement, but this ranking will be biased towards languages that generate lots of questions. A language that attracts more seasoned developers that also has decent documentation will rank lower than it should.
If you had said their design was "weak", I wouldn't have a strong argument. You said their design was "unprofessional". Strong disagree, and disagreement worth having: people here are too hung up on unreasonable standards of "professionalism". "Professional" is a best practices standard. It very much depends on context. Angie's List is a giant site in Exec's space. Exec's launch website is to my eyes totally professional, cleaner and better written than Angie's List.

What, exactly, do you think is more professional about the redesign?
More info here: http://www.rawstory.com/rs/2012/04/09/sopa-supporters-await-...
Gonze! How are you my man?!
Excited? Definitely. Not sure about knowledgeable. ;)
Venture-capital fundraising plunges 35% in first quarter
The video wouldn't run in my OS (which isn't standard, granted, but still).

Most software that ships to hundreds of thousands of computers is software that must run on other people's machines. If it must, then it is automatically in the markets best interest to optimize to require less overhead since it will give them access to a larger portion of the market. If it is for their own internal servers, then again it is in the market's best interest to roll it in C or similar since they are able to make the distinction as to where it is worth it to convert it to a lower level language.
San Francisco contemplates taxing sites like AirBnB and TaskRabbit
I read that title as kind of tongue in cheek. I'm pretty sure Facebook could have built the exact same functionality for less money and in less time as it took to initiate and finalize the acquisition. Winning their users over may have been harder to do. I guess they just figured it would be easier to just buy the users. shrug
Viruses and bacteria evolve much faster than cancer, because they:

* Use horizontal genetic exchange, so different evolutionary branches can share features. This increases evolutionary speed exponentially.

* Evolve over a much larger eco-system, whereas cancer has to evolve "from scratch" in each individual over a relatively short time-span.

Thus, I think cancer should be a much easier problem, from the evolutionary perspective, than bacteria and viruses.
Feel free, I'm just glad my comments are well received enough to be quotable :)
When someone figures out how to combat sharing information covered by IP laws without large scale surveillance and censorship systems then maybe it would make sense. I can't even see how that would be possible, but who knows?

Right now "combating piracy" is a bad thing just like "combating evil thoughts" or "combating hateful speech" is bad, because the only possible way to do it causes much more harm than the stated enemy is causing.
I thought I read before that Facebook tried to buy Instagram last summer but it didn't happen (my guess is that they offered $500m). I think FB might have offered too low last summer, and has been watching Instagram ever since. Instagram's growth is amazing and they have the network effect in the mobile photo market. I personally think Facebook got a great deal at $1b and that Instagram will continue to grow and reach 100+ million users within the next couple years. $1b to acquire Instagram will look cheap in a few years.
One significant issue is that most programming languages are inherently temporally inexpressive, having either full order (imperative/impure functional) or no order (purely functional). Ideally the language would make it easy to organize statement in such a way that a programmer could indicate a partial ordering relation without having to use function composition. Additionally, a big problem with function composition in purely functional programming is that multiple long function compositions can only be ordered as monolithic units, however in many cases being able to order at the individual function level is desirable. If a language had an explicit notion of relative temporal index for statements (which could be adjusted) it would be a nice win for writing concurrent code. That would also let compiler writers lift a lot of the stuff they do up to the program source level as macros (which would be a HUGE win).
Probably depends upon your network of friends.

I never would have thought it a problem because in my circle of friends there are multiple dog owners, and when one wants to go out of town the other just takes in their dog for the time.
Tried the new GPU emulation, and got a warning that snapshots and GPU emulation are mutually exclusive.

There's no way I'm going to deal with cold booting the emulator instead of using snapshots.
Having an open mind does not mandate that one become an idiot.
مسلسل روبي الحلقة 35 
مسلسل روبي الحلقة 35

مسلسل, روبي ,الحلقة, 35

http://video.qlbak.com/11028.html
Good God, this article is depressing. I used to think we'd have some therapies to at least suppress new growth in my lifetime. If I'm understanding what he's written they don't even have a game plan for an effective treatment.
Better link: http://engineering.twitter.com/2012/04/mysql-at-twitter.html
Hiring summer interns for WP7 development
Position is for a developer to help us make our Windows Phone 7 client for our application. Please contact me at tanvir (at) seas (dot) upenn (dot) edu for more information. Thanks.
Wait — so how many newspapers have paywalls?
Yeah. The wiki article has a list of what they released: http://en.wikipedia.org/wiki/Atari_Corporation

One neat thing they were developing, but never came to light, was Jaguar VR. It was a virtual reality headset, using IR-tracking, which let you play VR games. Only a few working prototypes exists:

VR headset: http://www.youtube.com/watch?v=MFZCgNBxkcM

Game shown: http://www.youtube.com/watch?v=GJmnmRzWipo

Another of VR headset: http://www.youtube.com/watch?v=1NCQJrd-4rk
There are lots of kids programming in Lego Mindstorm.
http://www.alaskapublic.org/2012/01/20/statewide-lego-roboti...
"For the past four months, over 1,000 students across Alaska have been building robots – LEGO robots..."

I imagine based on the fairly few (if enthusiastic) posts about Scala on HN that Lego Mindstorm programming far outstrips Scala programming in the US.
Short of an international software developer cold-call survey, all "language popularity" estimates are going to be weighted towards some specific community.

TIOBE seems weighted towards blog/article writers, using GitHub et al. would be weighted towards the open-source community.. Stack Overflow is also a fairly cohesive community, though a harder one to name: people who ask for help in online Q/A sites?

For instance, I'll bet that none of those three communities overlaps much with government contractors. Within the firms I've worked with, they are very, very hesitant to even use the Internet, let alone participate in it. Information comes from dead trees only. They are also staffed by a much older crowd. And they have a ton of software developers keeping Ada, C, Assembly, and Forth alive and kicking.
They're not liable simply by dint of receiving the information, meaning that there's no legal disincentive for them to accept information about compromises, such that an elaborate, expensive, and time consuming legal facade would be required for them to receive it.

It's not a blanket shield of liability against breaches. It confers immunity from liability only for transmitting and receiving information. In the spectacularly unlikely event that Google received information that they were compromised through this channel and then did not act on it (!), they would still be liable for information that comes to them about the compromise through other channels.
> This is amusingly confusing.

Not so confusing when you understand that RT is a Putin mouthpiece.
(1) Well, he said

> If properly encrypted with an authenticated encryption mechanism

(2) Being on one's connection is the default assumption of the internet security model.

(3) Right, the confidentiality of the site's data from the site's user may not be critical. But if done properly it does allow the site to ensure that the data it stored has not been tampered with (except perhaps to drop it or replay it). Surely this can be useful.
Hundreds of millions of dollars and years of clinical trials are needed to prove if DCA is effective or not. You can't just say "trust me, they looked into DCA and found it wanting". Looked at it how? Have they done years of clinical trials? did they spend millions in R&D on this?
It's not lack of money at all. How many researchers, worldwide, do you think have the expertise necessary to make a nontrivial contribution?

The problem is we simply don't have the technology to develop a cure for cancer, and we don't even know the precursor technologies we need to develop a cure for cancer.
How do you figure that? Exec has what appears to be the same price as Taskrabbit.
Are they not still a private firm? Who is the due diligence owed to? I'm sure they've been watching this and mulling it over for quite some time and that the folks in charge approve. That's all they need to do.
Funny that you noticed, I went and read the article on zombie rays:
http://rt.com/news/weapons-future-zombie-media-486/
and it turns out the article actually tries to debunk the "zombie rays" hoaxes and explain what's actually possible and what isn't when talking about experimental weapons.
> If something is "ten years away", it means we simply don't know how to do it

In terms of medicine, human trials generally take ten years. If something is ten years away, I would take it to mean there is a promising solution now. It just might not look nearly as promising in ten years, after it has been rigorously tested on people.