skysight-inc/HackerNews huggingface dataset:
Yes but no. Allergies are a very particular reaction- you don't get allergy symptoms when you're sick. They're predominantly IgE (immunoglobulin E) which is a detector antibody rather than a neutralizing antibody (although those terms aren't really favored now). IgE activates a body response like anaphylaxis.

The antibodies in this study are IgG (the "normal" antibody) and IgM. In this case, these antibodies latch onto and neutralize/clean up the antigen. They cause much less of an immune system activation, and can act like a passive defense.

TL;DR: allergies are a subset of antibodies for substances, and in this case the antibodies found were non-allergenic.
"In htmx 2.0, our only breaking change is likely to be dropping IE support." from a comment by the engineer who writes and maintains htmx.
the fact that no-one is getting fat by drinking litres of olive oil would seem to conclusively disprove your hypothesis as previously stated

the cost of edible oil has not been a bar to access to calorie-dense foods for at least centuries if not millennia

clearly the proximate cause of obesity is eating more and metabolizing less (both by way of lower exercise and lower basal metabolism). but why are people doing that? did they lose the gene for willpower in a single generation? that seems implausible

it seems to closely follow industrially-mass-produced foods, but the relevant feature of those foods is clearly not that they are more convenient or higher in calorie density than a can of crisco or an amphora of olive oil; they aren't
I don’t have a real answer for you but I will say that olive oil works well for this.

I worked on a Christmas tree lot through my winters as an undergrad and olive oil always worked well. Of course then you need soap and water to remove the olive oil.
PJ Vogt (formerly Reply All) recently did an interesting episode on his new podcast about this exact topic[0]. It's worth a listen. It really helped to clarify some meta-thoughts about how attention works, how media consumption influences us, and how I think about Twitter (and people's relation to it).

Like, at one point, PJ talks about how he's witnessed people at the bar talking to a friend (purportedly), but in a format that seems to be talking to an imaginary twitter audience. The way people talk, communicate, quip, etc on twitter is bleeding into discourse OUTSIDE twitter. I tend to agree as I've seen this. Worse, when I use things like twitter, I find myself being unintentionally obtuse, contrarian, quippy, etc.

You are a product of what you consume. How deep of thoughts can be conveyed in 140/280 characters? And perhaps more importantly: does such a shallow medium give you a proper opportunity to explore your thoughts on a topic before you begin to formulate an opinion/response?

[0] https://pjvogt.substack.com/p/how-do-i-use-the-internet-now
You've identified what needs to change.
I guess until all autonomous vehicles are fully equipped with real sensors (likely both lidar and radar) so that cars can almost-mechanically stop before foreseeable collisions without worrying about AI hiccups. This is technically possible even now, but it's way too expensive for now.
Congrats, that's a great position to be in.
Is it working in the media for him, though? No.
Ever since I've started seeing outright discrimination against males in tech, I've adjusted by always answering prefer not to say / other.
Hi, it's me, I'm the outlier, it's me
It's disappointing seeing how many of these startup frauds are basically connections laundering at inception. Makes you wonder what % of successful startups are the same (far from 0).
I already found it odd to publish before the trial, the trial wpupd have been the perfect final chapter.
Yeah, you're not wrong about the mindshare problem. But it somehow at least in my mind differs from other "stillborn" older languages in that it keeps improving. The end result is that it still feels modern in the year 2023.
I don't think freedom is an option for him anymore.
Looked at the place's reviews in Google maps: https://maps.app.goo.gl/PdYt2Yezq5if8wH78 Looks like they have a dog porch too? Do the dogs get the $50 charge if they are barking?

Also, indoors on this place suffers the same problem almost every other modern restaurant has, there's absolutely no sound dampening whatsoever. All hard surfaces, MAXIMIZE THE NOISE. Hard of hearing/elderly people I know complain all the time about this, can't hear yourself think because sound echoing off walls/ceiling/floor everywhere.
> ICE cars won't be outlawed if there isn't an acceptable alternative

Not explicitly.

But new gas stations will stop being built [1]. For-hire cars mandated to go electric [2]. Parking spaces reserved for electric cars only. Perhaps HOAs that ban the running of combustion engines on their streets. Nudges here and there that make it more annoying and expensive to own a gas car.

[1] https://www.latimes.com/california/story/2022-07-11/californ...

[2] https://www.nyc.gov/assets/tlc/downloads/pdf/green_rides_ini...
Avaje HTTP 2.0 Released
This is the equivalent of saying, we need strong protections on the Internet, because child pornography exists

It’s not an actual argument because it doesn’t have specific measurable distinctions between deaths related to driverless vehicles versus driver vehicles

We don’t have these types of measurable capabilities because we don’t actually have the data that shows what is the fatality rate per million miles at the scale of integration that an entire fleet they have supplanted the taxi industry would do.

You’re better off actually evaluating what is the death rate of taxis compared to individual drivers because the individual drivers are not going to be replaced at the same rate as taxi drivers and so the taxi drivers is the first more important number to evaluate with respect to traffic fatalities

Unless you’ve done that specific math, and walk the dog out, including the Wayno reports, some of the cruise reports, and some of the reports from Tesla (which killed a guy if you recall) then you might have an argument

As it stands, all I see with driverless cars is we’re trying to replace humans in an entire labor category, and we have nothing for those people to do

I suspect that is actually a much bigger problem than the theoretical reduction in fatalities on roads
PG is also the base for the liquid used in e-cigarettes
Interesting YouTube channel, looks like it is worth a watch.

You'll note even he conforms to the algorithm, though. Just look at all of those video thumbnails with his face.
https://docs.oracle.com/en-us/iaas/dbcs/doc/back-database-ob... and https://learn.microsoft.com/en-us/sql/relational-databases/t... are a couple examples.
Doesn’t mean we all must enjoy it and take part
Coffee grounds or that mechanic paste might do pretty well also
Don't you have to defeat a safety interlock to allow hands off the wheel driving in a Tesla?
It's frustratingly close to correct. Since it's on local disk, it winds up being cached in in-process RAM, which is..... still not zero latency... but has so much less latency compared to talking the to database over a network stack... that I'm alllllllllmost sorta kinda okay with it.

Almost. lol
Without having to redo their setup when their network was not intercepting connections by default, which it could have been doing.
> the CPU and RAM limitations led me to traditional RAID there

IIRC there was some talk that RAID-Z lead to write amplification compared to mirrored drives, thus not good for cheaper SSDs. Haven't had time to sit down and think it through, does anyone know if thats right or wrong?

> I used 3 4 way switches from aliexpress

Did you find any that were significantly cheaper than ~100 USD?
Since he doesn't like next.js, you expected him to offer a course on it?

I really don't get the reasoning here...
My daycare has a fee if youre 30 minutes late, but also a 3 strikes policy. So this doesnt escalate. Most places there are more people looking for daycares than slots (especially for very young kids) so they can be choosy.
1Password vs. Dashlane: The Ultimate Guide
I'm continuously amazed that people called him a "charismatic" speaker, etc. Really amazes me that this is the bar for an exec, company leader these days.
Yes, although the ones I've seen today all have humans in the driver seat.
I'm more annoyed by this in blogs. Substack started as an anti-Twitter, with long-form intentional communication and calm newsletters. Now, it's slowly shifted to a growth hacker cesspool of pop-ups, recommendations, and dark UI patterns. Beehiv is worse. We've ended up with an explosion of content blogs by people who don't value content.
> Overall wage growth in real terms has been stuck for some time - now that it's 1% (1%!), it's considered among the highest for 20 years (for 20 years!).

Yes! Exactly! This is the disconnect right here. First: real wage growth is always a good thing. It's not always above zero, by definition. Sometimes real wages contract. This i good news you're posting.

And specifically it's historically good news: making a reasonable assumption about your age, wages are growing faster for your market right now than they have at any time in your career so far.

And... you're trying to spin that... as... "bad" news? Seriously, how?

Again, this is a meme. Someone sold you a line and you bought it. Seriously, what number do you think should be in that box to make you happy if "best in two decades" doesn't qualify?
You haven't eliminated jobs: the bosses of people who are getting laid off are, after they buy your software. Crucial difference.

> It is not a crime to deprive someone of their income stream

No, but it is a crime to steal. If someone has created digital goods, put them up for sale, and you acquire them without paying, that is stealing. The fact they didn't "lose" some physical product in the process is irrelevant. You have cheated them out of their commensurate half of an even exchange they have offered. If you don't like the exchange, find it too expensive, the product not worth it, what have you, that's fine, you are free to not complete the transaction. You are not free to bypass it and gain the thing you weren't willing to pay for without paying.
it's almost as ineffective when undertaken on your own initiative; that's where the 95% number comes from

diet and exercise is clearly the proximate cause of obesity, but the question is what drives diet and exercise, and what changed so suddenly?
> how do you tell and how long do you have to wait

The day we can define it is the day we can create it. Until then, genius and insanity will be indistinguishable until after the fact. (That said, there are clues.)
The author probably lost their savings investing with Sam Bankman Fried/FTX. Person has an axe to grind.
For this reason I love drawing diagrams on whiteboards and absolutely hate taking the step of putting them into a wiki/README/etc.

One thing I miss about in-office work is that people would spontaneously draw diagrams in meetings. The same diagrams would get drawn over and over again, evolving. And everybody did it, so everybody was rehearsing the architecture in their heads and had a basic grasp of it. It was like a tribe singing the same songs over and over again, trying out variations and evolving the “official” version over time.

This doesn’t happen (IME) with remote work. Drawing diagrams takes for-fricken-ever so people tend not to do it in meetings. Best case, someone shows up with a diagram, and it stays up while people talk about different ways of doing it, and after the meeting someone makes the changes that were suggested.

It really lacks the collaborative value of someone walking up to the whiteboard and saying “what if we did this,” not hesitating to make changes because they can do it in ten seconds and then wipe out their changes and redraw the original in few seconds if they want.

When somebody starts making changes to a diagram in a remote meeting, it’s a sign you’re going to be there for a long, long time.
Actually, in the US, where copyright law is thick, you can.
What would be a good library /tool to auto arrange a complex graph (DAG) like the Blender/Unreal/Houdini node interfaces?

I would expect some options to set constraints, like the first input staying always aligned with the previous node.

Here is one of these DAGs: https://cdnb.artstation.com/p/assets/images/images/026/099/2...
> difference between shopping at costco and shopping at walmart

Could someone please explain to me what is implied here? I've been to the USA only once, and I didn't visit neither a Costco nor a Walmart. The only difference I could point to between them, is that no "Costco people" phenomenon exists on YouTube.

Sincere thanks in advance!
Late game does get bad, ill admit. Thsts just more incentive to win by then!
some content creators I click on _despite_ them having to do the click-bait stupid YouTube thumbnails.

As an aside - word you may have been looking for is irrespective, or perhaps just plain old regardless. irregardless is not a word.
Until you run into one of the many poor design decisions that DRF has painted itself into a corner with and has been carrying with it ever since.

Django Ninja is a breath of fresh air.
Great work Dennis!
It remains possible to produce great original works of art, independent of popular trends. For example, Thomas Pynchon is a modern-day example of an author still creating significant works of literature, who is notably reclusive from the public view: https://en.wikipedia.org/wiki/Thomas_Pynchon
There is a project to connect GPT-4 and lean, but I doubt they will make a lot of progress until they can finetune GPT-4.

https://www.youtube.com/watch?v=CEwRMT0GpKo
Only partially. As an employee I would resign from a company that insisted on MitM'ing my connections. But from the position of the article, it clearly would have been valuable to have request captures from the start rather than having to try to reproduce the malware a second time.
I like ChatGPT’s answer better than yours. Rust’s cost generics and C++ aren’t dependent types in any sense. And saying “the type of one variable can depend on the value of another” is vague but a good intuition pump.

Since I guess we’re doing dependent types explanations I’ll give it a go. Dependent types extend a type system with two new type thingies: 2-tuples where the type of the second element depends on the value of the first, and functions where the type of the function’s return value depends on the value that was passed to it.
What is not really mentioend is that authenticity is not really guaranteed unless you know the people well, from irl meetings following them for a long time (i.e interviews). It´s very hard to find a single source of a platform for "authentic" content or connections. One day a person you know might post something insightful the other time it´s a marketing LinkedIn how to xxxx.

Twitter is not as authentic as it used to be but I think this happens to any platform. Look at facebook.
At a massive performance cost.
That's an interesting way of looking at it, it's not just different from person to person but also from hobby to hobby. For me climbing is mainly about 1, but on reflection I defnitely spend more time talking about competative games than actually playing. I can also think of a few people who have hobbies that focus around 3 and 4.
Show HN: Cicd Kexa action compliance multi clouds
pre/post deployment compliance / security verification across clouds services with Kexa in CI/CD.
I would lean towards 10 years but only because leaning towards an extreme number would probably result in a reasonable number like 20/30/40 anyway. The only part of copyright that I haven't convinced myself of is whether being able to pass "ownership" of ideas down to your children is something that should be important or not.
like the article says, the takeaway isn't to panic, but just to consider dark chocolate a food you don't overindulge in. obviously you want to avoid contaminants, but some degree of exposure is part of life, and it's the dose that makes the poison.
I am planning on building custom BLDC driven actuators and I need to manufacture my own gears for that...
> “The owner came out and told me he was adding $50 to my bill because of my children's behavior. My kids watched a tablet until the food arrived, ate their food and my wife took them outside while I waited and paid the bill.”

This sounds like less about shaming the kids for their behavior, but more about shaming the parents for what the owner considers “bad parenting”.

A kid watching a tablet is definitely not going to disrupt other guests or the people running the restaurant, but could definitely be considered (by the owner) “bad parenting”.
No. It's up to the judge to decide what to allow as evidence or not. It has nothing to do with your right to a trial by jury.
The real logical problem with his approach is not the relative risk. It's not the linear no threshold model.

It's the use of effective whole body dose to estimate the risk associated with a dose to part of the body. Exactly zero radiation biology organizations recommend this. Most explicitly caution against using effective whole body dose to estimate radiation risk. Effective whole body dose is only used for population-level estimates.

For example, one of the most radiosensitive (wrt cancer) organs is the thyroid. But his thyroid is not in the beam. Also the skin is exposed more than the interior on CT, which increases the risk of skin cancer. These corrections are standard, while alternatives to LNTM are not standard.

Then there is the effect of age. Most radiation related cancers are delayed by a long time, and the faster that cells are dividing, the greater the risk of DNA damage. But Scott is old, which is also why older workers were preferred for cleanup at Fukushima.

D_eff can get you within an order of magnitude I suppose, but you shouldn't express it with two significant figures — it's misleading precision. You could say 1/1000 or maybe 1/700? But you really need more detail for any kind of meaningful medical decision.

Anyway, that's my rant as someone studying for the board exam.
Previous major discussion: https://news.ycombinator.com/item?id=35815810 - "White House announces new actions to promote responsible AI innovation"

Here's, at least, some official words about how the current admin's advisors might be thinking about the considerations for adoption.

Another interesting bit aside from the administrative task of ensuring constructive adoption of AI would also be facilitating progression, defense, and contribution.

Some more perspective on what the federal government is going on:

- https://www.cisa.gov/sites/default/files/publications/STRv4_...

- https://github.com/Trusted-AI/adversarial-robustness-toolbox

- https://www.darpa.mil/program/explainable-artificial-intelli...

- https://www.nist.gov/system/files/documents/2023/03/30/AI%20...

- https://atlas.mitre.org/

- https://www.nsf.gov/cise/ai.jsp
I think Twitter is actually useful because it reveals what people are authentically thinking. If you ever want to stop hero worshiping someone, follow them on Twitter. You'll quickly lose all illusions about their "genius" or supposed expertise on things beyond their narrow sub-specialty, and realize they're a flawed human being like everyone else.
> It’s not a crime to deprive someone of their income stream

It is in some cases, for example, DCMA and copyright that make it illegal to copy digital goods, the topic of this thread.

But as an aside, laws are (generally) based on ethics, ethics are not based on laws, so even though it is illegal, it doesn’t conclude anything about the ethics of a situation.

There are many arguments for why piracy is unethical, but the simplest might be using Kant’s categorical imperative “a universal ethical principle stating that one should always respect the humanity in others, and that one should only act in accordance with rules that could hold for everyone” [1].

So could piracy hold for everyone? If everyone pirated Marvel movies then Marvel would not be able to make $100+M movies and these movies would not exist, which is a contradiction. Therefore piracy violates Kant’s categorical imperative, therefore piracy is unethical.

[1] https://iep.utm.edu/kantview/
I don't see any tribal knowledge being passed on here. It seems django's admin panel is ugly because nobody has interest, enough, in investing to make it beautiful. And you were looking for a fancy answer with wisdom as "it's to discourage its use for consumer blabla" while the obvious answer is the right one. It's ugly and there isn't enough interest to change it, because it works well enough to cover the intended usecases. The other usecases would need more investment, and nobody invested.
This is probably the stupidest question many of you will encounter today, but:

If soap has an extraordinary ability to destroy viruses on our skin ... can eating soap give us some of those benefits for viruses that are already in our bodies?

I'm not seriously envisioning chowing down on bar soap or using liquid hand soap as a salad dressing. But are there ways to use the _properties_ of soap that make it good for killing viruses in something that can be ingested? Or do those properties only work for surface-level viruses, and we need to use other strategies to kill viruses once they're in our bodies?
People often buy things even if there are better free alternatives because they don't know any better. Otherwise nobody would be using the utter garbage that is Microsoft Teams, for example.
You have to nudge the wheel every 30s or so, and respond to audible prompts to "wiggle" the wheel or steering control will be disabled for the rest of the drive.
It is not only Elon Musk who is to blame for the decline of Twitter. After all, other social media platforms, such as YouTube, have long been using eye-catching content to generate revenue. Even before Musk's acquisition, Twitter was already engaging in monetization practices such as redirecting users to external sites, allowing influencers to post sponsored tweets, and inadequately moderating content.
Yes, that's the problem.

It has mostly died down but a segment of the developer community took great exception to the designers of Go calling it a "systems" language when it had GC, which, as everybody knows, makes it worthless for all tasks ever. (Sarcasm.) However, in my experience, the bigger problem with it as a "systems language" is that the runtime has already spawned off threads by the time the first line of any user-controllable code has been executed, and goroutines get mapped arbitrarily to OS-level threads by the runtime (there's an option to pin a goroutine to the thread it is currently in, but not to a specific thread, IIRC), meaning that anything that is set at the thread level in UNIX is effectively unavailable to you in your current process.

In light of that fact, and in light of the fact I see no code here, I remain unsure how the original poster actually has integrated pledge into Go.

The only C code I have under my maintenance is code whose sole purpose in life is to be run as setuid, take some command line arguments, open some privileged files, start a known executable, and pass the file handles to that executable directly, so the unprivileged user running the executable can not see the contents of those files. (The system is locked down in other ways too, e.g., the users can not run strace to see the contents, LD_PRELOAD is locked down, etc., and as the final defense against internet rando systems designers criticizing this design on the basis of a single sentence, it's not the only line of defense here either.) I would _prefer_ to use Go, but there's no safe way to drop privileges in a Go executable, and for various technical reasons the exec support in Go does not _quite_ cut it. (It is close, but no cigar; we can not quite specify all the details we need from the outside.)
weird that nobody write about this.

My friend in Milano is a pro on this, and just wrote me that results are incredible!

(this confirm once again my feeling that a lot of good content is cited here in HN, but goes off totally ignored)

:(