I read a study once which suggested that exercising immediately after wake up before eating or drinking anything other than water (if needed) was the equivalent to 1.5times the exercise after eating or drinking.

Perhaps this is why military basic training the world over involves running around before breakfast. You can do a 30min run before breakfast or a 1hr 30min run after breakfast. How do you spend your time wisely?
Have you looked into the hormones that wake us up? Are they good for body building?

Chemistry is very useful, there are 2 enzymes and hydrochloric acid in your stomach, what uncoordinated chemical reactions will take place in that part of the body, when you eat or drink things and the chemical compounds come into contact with each other?

I personally avoid ingesting any chemicals as sulphates because they react with hydrochloric acid and become sulfuric acid, and I dont need to be oh so slightly dissolving my tissues and membranes in the body even though it might be a good persistent low level wormer and parasite treatment, but you will find a good many health supplements using them, a quantifiable example of the blind leading the blind perhaps?

Where people might say avoid sugars, I'd say look into manganese and chromium and see what effect it has on the body.
For example, there is a postulation that chromium potentiates insulin signalling. Chromium picolate being taken in amounts upto 2.5grams a day is used by some for weight loss, and whilst there might be some truth about chromium's involvement in energy metabolism, is picolate the best compound form for chromium, when you can get it in other salt forms and compounds like chromium histidine or chromium nicotinate? I then feel like capitalism is failing us when searching for these compounds and I'm still searching...

Have you see what a ketogenic diet does to your mineral reserves in the body? Did you know a high fat diet causes more manganese to be pooped. Diet induced obesity is a real medical term. Does the brain become diabetic long before the body shows any symptoms?

So my best tip is, Do Your Own Research (DYOR). You'll find anecdotes on places like reddit, and other health chat forums, these can give you investigative leads. Try to find studies to back them up.

The drug companies also have a vested interest in understanding the human body, they need to understand and be able to quantify the different pathways in the body, whilst being mindful of regional dietary differences, in order to make sure their man made compounds can alter a chemical process in our bodies. So trying to learn the chemical pathways, in the body is something worth doing.
These man made compounds can be very strong mind, resistant to a "brute force" mega dose of some supplement. SSRI's are a good example of jamming open a receptor whilst not addressing the underlying cause, which will be dietary. And some chemicals will switch genes on, and switch others off, and there is plenty of redundancy in the body to compensate for dietary shortages and excesses. Decyphering ourselves is perhaps the ultimate chemobiological puzzle on this planet which perhaps explains why the cancer industry keeps on growing!

Universities also publish studies which can be useful as do some hospitals that write up a brief report on individuals typically presenting to A&E/ER rooms after the ingestion of some chemical in one off's or from the repeated over consumption of something like chromium picolate.

Survival of the fittest can take many different paths.

TL;DR: get a private prescription for testogel and watch the fat drop off and the lean muscle mass increase! Your mental health will improve enormously and you might even start engaging in risk taking teenage like activities again which the state does not like. Being a shareholder in epilation/depilation products are not mandatory either ;-)