skysight-inc/HackerNews huggingface dataset:
This is a website for people in the tech industry, with additional focus on business. There are also subjects that simply cannot be discussed here (which is good). It’s those limits that constrain the conversation which makes this place “less toxic”. If it was a free for all where you could post anything, well, the place would go to shit immediately.

I feel like you’re attacking attempts at inclusivity in general with your comment, which seems misguided. Inclusivity and trying to accommodate people is not what causes toxicity.
I love Obsidian over all the other tools that I have tried.
https://ashishb.net/all/why-i-prefer-obsidian-for-taking-not...
> An anomaly of this size warrants alarm.

Yes, it does.

> If not proof of imminent ecosystem collapse, it seems foolish to 'wait and see'.

Jesus Christ. I never said that.

Read what I wrote, not what you think I wrote.

> Though I take your point that defeatism is worse, but I doubt OP is defeatist.

You should also try re-reading what they wrote.

> That's an even more sensationalist spin than what the OP wrote

Fair point. The OP didn't say we'd all die by 2030. Just that the climate would collapse. My bad.
The government let people on Wall Street keep their RSU style compensation after 2008. It's not like most engineers can sell their RSUs except on quarterly redemption days. Or the government could otherwise match the compensation. It has a lot of money.
A-ha! Now those dates make more sense.
Docker grew too fast. They chased VC dollars for what really was just a cool open source project. I spent some time at their first office in SF ten years ago for meetups. They had a really cool unique culture. I think that just doesn't scale some times.
First I would like to state that human genetics are very, very complex and we still do not have a complete understanding of them. For example, only relatively recently has the field of epigenetics made major advancementa, which (broadly speaking) studies how a cell's behavior can be changed WITHOUT it's DNA being changed.[1] This brings into question the age-old questions about environmental impact vs genetic impact in even greater detail. Anyways, sidebar over.

No, we are not completely sure how many chromosomes play a role in determining eye color. However, we do have a pretty good guess. Most recent estimates I found out the number at 16. OCA2 and HERC2 have the largest impact on eye color, but, there are many OTHER genes that also have smaller impacts on eye color. [2] That article I cited is actually amazing. But, it does touch on some more advanced subjects that are more introductory college-level biology or AP Biology than standard high school bio e.g. Gene Regulation, introns and extrons, etc.

To answer your more general question, in my (admittedly only mildly less basic, introductory college-level biology) opinion, it is unlikely that we will, anytime soon, reach a point where anything in genetics can be completly, 100% definitive.
This is not to say that we haven't made amazing advancements in the field of genetics and biology more broadly. BUT, it would be a mistake to take for granted the complexity of the human genome. There is most definitely things we still do not understand about the genome, and will not for some time.

But, practically speaking, while other genes may have impact on some simple phenotypic traits, such as eye color, we can generally make an accurate guess based on only a few genes. In eye color, for example, one study was able to predict eye color with only 6 genes with about ~75% accuracy. [3]

The crazy part is, sometimes the genes that effect the phenotypic trait, don't actually store genetic material that determines the trait. In other words, they don't DIRECTLY determine the trait at all. Rather, the only effect ORHER genes which then effect the expression of the trait more directly. You can imagine that this could become very complex very very quickly when you have multiple genes effecting other genes which effect other genes, not to mention accoubting for environmental and demographic baises when doing these studies and you begin to see why this genetics is such a difficult field of study.

Apologies for the long post and rambling. Hopefully I was still able to provide you with some mediocre introductory-collage-level biology

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791696/
[2] https://www.nature.com/articles/jhg2010126
[3] https://doi.org/10.1016/j.cub.2009.01.027
I usually ask for no ice. You get more beverage that way too.
Obsidian's Manifesto
Also don't these only ever need to be computed once
The obvious way to replace housing in Lahaina is to rebuild what was there. Zoning regulations wouldn't need suspending.

They definitely should suspend permitting to expedite the process, whichever way they choose to go.

https://www.hawaiibusiness.com/hawaii-building-permit-delays...
You guys keep focusing on the wrong thing, salaries are a first order solution. What needs to happen is that the average salary can provide a citizen with a comfortable and simple life (housing/shelter, food, clothing, etc.).

Jacking up salaries without bringing the standard of living for the rest of your society will only lead to a continued breakdown of the social fabric that we have been seeing steadily happening over the past 30-40 years.
Your idea of a rugged laptop must be one that never leaves the desk
It's a slight exaggeration of the information content to report the data size using an ASCII encoding. Since there are 4 bases, each can be encoded using 2 bits, rather than 8. So we're really talking 750 megabytes. But still mind-blowing.
>I cannot understand why anyone would want to deal with fediverse anything.

for reassurance and redundancy. People going rouge or sites being compromised by greed or other issues are inevitable. But if one server goes down (literally or figuratively), you got 29 other servers to lean on, and it makes adding a new 30th easier.

>I want one with hundreds or thousands or more

that's still possible. Meta's new "Threads" may in fact be that. But the issue of how the internet is converging towards a few select corporations is an issue not exclusive to the fediverse. Having any kind of new forum in the 2020's overcome the networking effect is a massive feat.
My instagram account was also suspended recently, with no explanation. I did nothing wrong. I had a few followers, and I followed, maybe 20 or 30 accounts. No idea why it was suspended.
If the United States is convinced Belarus (or Belarus and Russia) are about to use their nukes, they very well might do a preemptive strike. I'm sure, at the least, it's been wargamed out.

But maybe they'll just tell the Ukrainians (or Poles) where the nukes are and stand back.
I'd rather these ideas spread to others, potentially younger readers, than never have to read a trope again. I'm not sure it will ever change if we just accept it and never discuss it again.
If I’m getting fast food then I’ll have a lid. If I’m at a sit down restaurant they will bring me one anyways. A few mixed drinks are preferable with a straw in my opinion and that’s usually the only time I grab one at home. I hate metal straws.
Agreed.

Honestly, this is starting to feel like copyright holders using the Big, New, Scary AI as a strawman to attack Fair Use.
A lone "thanks" doesn't seem to contain very much human element in it either, though; that just feels like somebody wanted to make a comment but couldn't be bothered to provide detail. What specifically are they thanking? Does the link make their life a little better (and if yes, how, so that others could emulate making more people's lives better)? If it was in reply to a comment, did they just read it or actually try whatever it was?

I think I dislike it because it reminds me of the busy exec replying with a single word, and that is definitely lacking in humanity.
How could we afford to run the software if the transistors were two micro pennies more?
This is exciting!

BTW. if you want to know the applications of this work, have a look at this ACM SIGPLAN Keynote: https://youtu.be/JTU3JYp3JYc?si=jOZz611ATQar3Gec (helped me understand DNA more than all biology classes at my high school)
Man if only there were some sort of super obvious solution to this missing across every industry in america
Dude, what common sense approaches about pregnancy do you think go against the scientific recommendations?

Please take a look at the CDC data over the last century. In 1915 infant mortality was _10_ percent. Maternal mortality was around 0.8% in 1900.

https://www.cdc.gov/mmwr/preview/mmwrhtml/mm4838a2.htm

Are you seriously claiming that these things dropping an order of magnitude has anything to do with common sense, or not listening to doctors?
I’ll stick with https://pairdrop.net, doesn’t even require any installs or downloads.
We would have to employ Hollywood to young teach people that math is awesome.
Comments like this really make me angry. As if the stigma surrounding getting help with your mental health weren’t enough, people feel the need to specifically attack parents seeking help for their children as lazy and uninterested in “truly helping” them. The slipperiness of an attack like this is that anyone can cite anecdotes (real or imagined) with an air of superiority, when you haven’t actually shown any credentials except cynicism and doubt. As a bonus, these comments tend to keep people who truly need help from seeking it, to avoid also being seen as weak or uncaring.

One thing in particular I’d like to call out:

> there is no known diagnostic test that can physically detect the presence of ADHD in the brain or some other organ, diagnosing ADHD is merely a matter of observing and interviewing the subject

Yes, the diagnostic for ADHD is based on observation. But why wouldn’t it be? The most obvious symptom is _behavior_, which doesn’t require probing your brain or blood vessels to test for. By the way, this is also true for many other maladies, from paranoia to the common cold. But if you’ve ever seen someone suffer from paranoia, you would instantly recognize it. A trained professional can diagnose non-obvious symptoms over time, with help from the patient. Dismissing the use of our strongest tools as “mere observation” is an oversimplification of the problem.
Some more conversation on Mastodon here: https://mastodon.social/@kepano/110945642295048699
Just wanted to say thank you for not attacking/threatening the creator!
A little over 800 per 100,000 in 1900 per CDC data. Infant mortality was 10% in 1915.

https://www.cdc.gov/mmwr/preview/mmwrhtml/mm4838a2.htm
Then we have the problem of blowhards telling us how to live our lives. I’ll take my chances with PFAs please.
Or maybe more doable: preventative measures like "ear retainers" for nighttime?
Buy a super cheap email domain for ~3$ a year and set the domain to forward all email it receives (wildcard) to a predefined email address you control. Namecheap will forward emails for free.
A Rubens Tube (a.k.a.) a Standing Wave Flame Tube, or Simply Flame Tube
The public Human Genome Project used a group of people but most of the sequence library was derived from a single individual in Buffalo, NY. The celera project also used a group of people but it was mostly Venter's genome

https://www.nytimes.com/2002/04/27/us/scientist-reveals-secr...

I believe more recent sequencing projects have used a wider pool of individuals. I think some projects pool all the individuals and sequence them together, while others sequence each individual separately. This isn't really so much of a problem since the large-scale structure is highly similar across all humans and we have developed sophisticated approaches to model the variations in individuals, see https://www.biomedcentral.com/collections/graphgenomes for an explanation of the "graph structure" used to reprsent alternatives in the reference, which can include individual single nucleobase differences, as well as more complex ones such as large deletions in one individual, to rearrangements and even inversions.
what does this have to do with data science? Does this guy even know any data science?
This seems to be mostly focused on math, what could be a good TDA resource more focused on applications?
Buy our leopards eating people's face brand phones, we support right to repair now!
Why bother, just use Syncthing
“I didn’t realize you could raise less money.”
Yes, that is surface diffusion. When anything lands in the surface that is ‘adsorption’. Then those molecules can either surface diffuse, desorb, or go somewhere else :)

Usually water is adsorbed on everything we interact with.
Moderators shape the community. Whether or not that shape sticks after they leave depends a lot on the community and what rules they keep/enforce.

for example, r/fishing bans memes. What if mod A leaves and mod B allows memes? Experience says that memes proceed to take over r/fishing anf the community tone changes. Sure, r/fishing "exists", but does it exist for the reasons you subscribed?

You can even use HN as a whole here. How much do you think the tone of HN would change if Dang dissapeared tomorrow?

That's the issue that was understated during these protests. Moderation is thankless work and even without drama it can burn one out.
"Built to last"

The M key on my 2019 MacBook Pro doesn't work, Apple told me it would cost 2300$ to fix it. One key. For reference I could buy two more working MacBook Pros, identical to the one I have, for 2300$.
Why nother, just use Syncthing.
It's a term for a money pool that breaks the transaction trail in crypto
The copyright on the site is from 2009, so "inactive already" seems a bit unfair—even if that were the last commit ever, that's a 13-year run, which is a lot longer than I've ever maintained a side project!
I think the presumption here is that they are white and reducing the look of dark spots and not someone with darker skin lightening it overall.

A challenge with skin-related literature (and internet comments) is that there's always the unspoken assumption that you're talking about a white person unless stated otherwise. Even the article reads oddly of you start off thinking of them as a dark skinned person.
Synology has had great success with their window GUI...
What is this magic?! I didn’t know this was possible through a browser!
So why you want people's retirement funds to be "drawn and quartered"? Do you want all retirees to die in poverty, or just the ones who opened a Vanguard IRA account for their retirement savings instead of a Fidelity IRA account?
> The community went back to Cabal? What did I miss? :)

Cabal got better, stack stayed the same. It's more a cultural divide than anything at this point.
https://github.com/szimek/sharedrop

"If I was feeling paranoid and wanted to know if my files are being sent to some third destination..."

then I would not use a third party website. I would want to prevent this unauthorised transmisison to a third party from happening rather than discover it was already happening. By then, it would be too late. Even just having all one's transfers, IP, time, date, possibly browser fingerprint, be recorded in someone else's httpd access log seems unnecessary.

But I'm not feeling paranoid. Rather, I like downloads. I like so-called "native apps", otherwise known as programs. I like them written in certain languages. I like to read and edit the source code and to compile static binaries. I enjoy it. Javascript is not one of the languages I prefer. Nothing against it. I just don't have much need for it if I want to transfer files.
JS is so basic (compared to Python, Go, Java, or Rust) that one can easily make a framework which will do something specific.

You can then use it to get a job.
I think they're spiritually related, but my understanding is that Marvin actually invokes the LLM at runtime to execute an AI Function (which is why it can perform, e.g., sentiment analysis). Maccarone invokes the LLM to generate code during development.
Every time I rotate mine to vertical it becomes GIGANTIC
In that case, you might also enjoy https://jaykmody.com/blog/gpt-from-scratch/

(here's the raw code: https://github.com/jaymody/picoGPT/blob/main/gpt2.py)
Yeah, the thoroughness of this is very impressive..

Also nice how well it renders on a small phone screen, for a desktop OS simulation..

I just enjoyed a round of DX-Ball, that took me back a lot of years
Maybe militia, if you're talking about people who've more or less removed themselves from regular society to live in a compound, likely off the grid, similar to the group who took over the national wildlife preserve in OR several years back.

MAGA is way too mainstream to be a counter culture. QAnon is more like a belief in certain conspiracies than an ethos you live by, no?
> I'm reminded of the Louis C.K. routine about everything being amazing and no one is happy.

If AI meant the human was now free, I'd be happy, but ATM AI seems to mean the human will be jobless and soon homeless and starving.
Semi-related, but I reported a broken and un-maintained "partner" status provider, and Hashicorp asked for details and said they'd look into it. After a couple months I sent a follow up email with no response. It's still a partner provider.

The community provider qualifications are a joke and shows how much they care about users/the community overall.
The biggest problem I found is that Chrome Manifest V3 requires background.service_worker (they removed background.scripts), while Firefox Manifest V3 requires background.scripts (they never implemented background.service_worker)

You can generally have a common background.js file, maybe with a few conditionals, but the manifest.json file needs to be different for Chrome and Firefox.

I decided to keep two foo-manifest.json versions in a manifest/ subdirectory, and copy one to ../manifest.json depending on which browser I'm testing. It's a bit tedious. Not sure if a better solution exists.
I want flying cars and moving sidewalks like I was promised by The Jetsons. :(
I don't know what this is. But, i would start with the question if there's a lightweight operating system for the original NES.

If you can't find answers, then the answer probably will be "no". If you're able to find answers, then you know where to ask.

Your question is very welcomed on HN, but it's not the audience and not the technology behind for asking such questions. There are just a few guys in this world who know what to do. I don't think they're on HN minutly monitoring new articles. Additionally, your question will be at the bottom very quick. So you need some other "ask me something" where your question is visible prominently for longer durations and where the hackers hang up. I think you need other hackers for that, as the hacker in hacker news :) good luck
Maybe they can prepend the 'effectively' weasel-word. 'Effectively unlimited' covers 99.9% of users.
Looking in past HN the most relevant results seems this from 8 years ago linking to a company that does not seem to exist anymore: https://news.ycombinator.com/item?id=9487872
Not just sound but also touch and balance.
Top Gear – Dark Souls 2 Special [video]
You can't get rid of money until you can vastly reduce envy, jealously and violence. The entire economic system is set up to balance the exchange of value of labour across industries with those of power dynamics/capability to wage violence.

In Star Trek, they can do away with money primarily because the invention of the replicator (and other tech) taking care of the basic needs of society, which lessens the need for competition between people. If you've got robots that can clean sewers and a machine that can print food from thin air, you no longer need a complex system of competition to allocate who is doing the shit jobs and who is eating the shit food. We're currently all still chimpanzees fighting each other to the death, we've just abstracted the violence away to such an extent that you don't see it anymore. The losers are still dying in droves, but they're dying to stuff like overdoses, homelessness, or not being able to access the doctors and healthcare their wealthy counterparts can.

In my opinion, short of inventing the replicator, the absolute best thing we can do as a species is to get a mass produced humanoid robot that can be controlled via VR built as soon as possible. We then get people doing undesirable jobs to control the robots and train an AI until it gets to the point where it can do the job without a human on the other end. Not only do we free up all those people from doing shit jobs, we can retrain them to work on other pressing problems, like curing diseases or even one day far in the future, building a replicator.
"You cannot fill plates and then take them home."

If you're a fast runner you can...
Now there is rEFInd, a fork of rEFIt. http://www.rodsbooks.com/refind/
I'm curious if these 750MB + the DNA of mitochondria + the protein metagenomics contain all the information needed to build a human, or if there's extra info stored in the machinery of the first cell.

That is if we transfer the DNA to an advanced alien civilization - would they be able to make a human.
I said read the guidelines. Casually scanning the literature on pubmed shows babies that come out after IDK 39 weeks have sometimes not great outcomes, and it gets worse as time goes on.

You say "the baby will come out when they're ready", but what would you reply to "what if the baby wants to come out stillborn?"

When do you want forcible induction to be advised by the clinician? 39 weeks + 2-3 days for you to feel comfortable about the decision? Maybe a week if you're seeing a psychologist or like astrology?
In this case there is absolutely zero conflict of interest I can assure you of that. The only conflict of interest he has is making people understand the severity of actual ADHD in adults and in children and how you don't grow out of it and how it can 100,000% ruin your life as it did to his brother.
Because the consequence of filling every labor gap with immigrants is to suppress everyone's wages. You're increasing the supply.

And if it really is a critical industry, being dependant on available foreign labor is quite the risk. There's not really any guarantee they'll want to keep moving here.
With few prompts I just wrote a small script with a bunch of openssl commands. Saved me an hour. And it works. And it even explained it. There is AGI and then there is “practically agi”. The latter has been achieved with LLMs.
Blockchains transactions are public, which makes tracking individuals and the parties they conduct those transactions somewhat straightforward. Mixers take coins from various wallets, "mix" them through various methods, then transfer them to another wallets. This is meant to obscure the link between the original source of the coins and their ultimate destination.

Crypto coin laundries.
Can you name some of these factories?
For anyone else that wants to just skip to the language spec:
https://www.moolenaar.net/z/zimbu/spec/zimbu.html
That’s true but it’s never the highly nutritious grasses that cows/goats need like alfalfa, false plantains, millets etc. You would need to heavily supplement their diets, I would imagine.
I don't know, why didn't people use Google+ instead of Facebook? or Mixer instead of Twitch? or even Linux instead of Windows?

They all have the same issue of a Network effect[1] to overcome. Sure, I can whip up or take over a dead forum today and dictate the direction, but I will likely struggle to get a dozen users in a month, let alone a dozen comments. Meanwhile, there are probably 12 new sign ups for reddit as I type this message.

There's dozens of reasons why this is hard to overcome, but to put it bluntly: people don't leave if they are comfortable with what they got. if Reddit works for someone, why search out for some forum that doesn't show up on search to find maybe 12 comments abut something, when reddit has hundreds of posts to read? Users are metaphorically lazy, and the biggest sites feed into that.

[1]: https://www.forbes.com/sites/forbesbusinesscouncil/2022/10/1...