skysight-inc/HackerNews huggingface dataset:
There is a currently approved treatment. It’s basically an allopregnanolone supplement, given as an IV infusion over 60 hours, for $34,000.

There are much cheaper treatments for PPD, but nothing that would ever pay for the approval process.

https://twitter.com/jamesknochel/status/1688023798447316992?...
These are great pieces of advice, and something I wish I had followed earlier in life. I probably should be following one of them now even.
A lot of times the purpose is more on rate limiting than disallowing bot access. The goal to tell apart is on the premise that humans are a lot slower than bots.
“In case the Agreement is amended as described, we will post an updated version of it in our website, at which time it becomes active and binding”

Several years ago, a friend entered into a contract with Comcast for business internet and phone service that had similar wording and no actual URL for the site. My instinct was that would be unenforceable and unconscionable, but you’d think Comcast legal would have thought it through.

Any lawyers out there familiar with this type of wording related to contract changes being posted on a website, particularly where no notice is given?
Should we feel bad for folks who fell for misinformation campaigns, took horse meds, and as a result died...?
Is it okay to bury dead people at a park or athletic field? Is it okay for my dog to crap on your lawn? Show some respect.
> I'll try to reserve parking at the airport

this alone to me is ridiculous beyond words. So you not only take the plane, you also drive your own car to the airport. You drive a car. Now you have a problem. Here in Berlin it's 38€ per day to have your shit precious car wait for you at the airport. It's cheaper to take a taxi at that rate.

Anyway, solid first-world problems here.

Yeah, we're pushing it hard, and we try to lie to ourselves about convenience and whatnot, and we give a damn as for the fragility and complexity we create with our fancy systems. Way to go.
Clicked profile and saw MIT math and the rest. That's impressive.
Babe, I've spent at least half my adult life living in the USA. Not only that, but I'm from literal Canada, which is basically a thin, one-dimensional strip extending from the Pacific to the Atlantic, right above your circus, suspended like a trapeze. We are saturated in your news, your media, and your politics.

You honestly think that people living half an hour from the border don't get an opinion? When did America get in the business of deciding who could have opinions, anyway? So much for the land of free speech. RIP
Well I tried using Teams recently with a friend who had one of those Intel Macbooks, and it used so much CPU that it became unusable.

>(It's a massive battery drain and CPU hog, but other than that it works)

That doesn't fit with my definition of "works".
GPT controlling industrial systems is my worst nightmare
I had no idea who Mr. Devault was before this article.

So I googled, did some reading, read his blog some, and yes, he strikes me as one of those people who have entirely too many strongly held opinions, about a great many things that are probably not very important to peoples day to do lives - and will exclude people who do not agree with him in entirety.
Implicit can make things hard to understand meaning it should be used with caution.

But allowing CustomInt i = 0; instead of CustomInt i = CustomInt::Zero; or worse CustomInt i = static_cast<CustomInt>(i); isn't a bad thing.
> You aren't american. Why do you even care?

It feels extremely naive to think that American politics and culture don't affect the rest of the world.
It just isn't at all. It's still on-air in the US and much of Europe not to mention huge countries like India (where it is still heavily used) and China plus many African countries.
I've spent the last year managing all my packages with Devbox (https://github.com/jetpack-io/devbox).

Local dev, cloud dev, CI, production – all with the same config file. Fingers crossed my talk submission for PackagingCon gets accepted. It'd be awesome to share this new way of working with a wider audience.
I’d entertain a policy proposal that does this without too much damage to the ability to flexibly hire for part time and contract and freelance type work.
hmmm. Does this not assume that a cpu is shared among exactly 2 tenants over a long period of time?

And can‘t the cloud provider simply block access to the cpu api? Like they don’t allow you to create your own threads?

Just trying to understand this.
There are probably more website visits than that. People download games and bank apps and things like that, stuff they expect to use frequently, want fast access or offline ability, of they need hardware access.

There are still tons of things that don't need an app. Things that are inherently online and not accessed frequently work fine as sites.

The web doesn't limit what you can do that much, it limits how you can do it, which I think is a good thing. Less to break (Android API levels have the same effect) with fewer original lines of code. Less focus on clever and interesting code and more focus on UI and features (Although they try their best to reinvent the same js framework 1000 times).

A lot of the limitations are probably just Mozzilla hating anything that could be used for tracking, and not trusting users to manage permissions. The trend has been pretty strongly towards making the web very close to native apps, with all kinds of APIs.

Native apps fill a use case very well, that the web does not. That doesn't make the web obsolete.
At least in my experience, you need the job hop to get the change shift of role, industry, or promotion as well. I would be doing my previous bosses' job and then some, and show it in review cycles, only to get the 'yeah you're right, just wait a bit longer, we'll figure it out' over and over again. Leaving for another company was the only way it happened.
Would this affect other Python interpreters or just CPython?
I can only assume you pick up the USB sticks that litter your office parking lot and plug them in?

...apples USB security already works on the iPad, and only allows charging until you authorize the device.

And if you know anything about this stuff, that's better than other vendors.
I love how many references to Stack Overflow that PR added to the codebase. Always a good sign.
Was the code seeding by seconds since epoch, or nanoseconds since epoch truncated to 32 bits? Broken either way.

https://github.com/libbitcoin/libbitcoin-system/blob/a1b777f...

const auto now = high_resolution_clock::now();
return static_cast<uint32_t>(now.time_since_epoch().count());
> Is this really a pharmaceutical issue or a societal structure and support issue.

Any if it is? We surely can't solve every, or even most societal issue that causes it.

You can continue to support improvements to the societal issues of the world while still supporting pharmaceutical interventions for those who need it right now.
LOL - no, a bit random.

I was typing on my phone and running out of time.

Broadly, it was a half baked thought that our Western culture heavily promotes ideas that are anti-Earth in a way.

Ideas for instance where Elon Musk is talking about saving humanity by getting to Mars, or creating artificial meat as a solution to our food crises.

These ideas suggest that the solution is to engineer our way out of a problem of our own making. The problem rhetoric being that Earth cannot support us.

This runs counter to the thinking that we are bound to this Earth because we are part of it. We are one and the same. So we should respect it and work with it.

Watts talks about seeing the Californian hills in the 60s, being carved up and houses being wedged in to the landscape in an artificial way. Where no consideration is given to working with the land, instead we try to dominate and shape it.

Like I say, it's a half baked idea that I'm not really expressing very well I don't think! :-)

I'd love others to straighten me out, or put me on the right path! :-)

I did laugh a while back when in one of Watts' talks he mentioned Plastics being the solution to Deforestation and Paper Wastage...

Engineering a solution to deforestation using plastics didn't work out so well for us.

Fast forward 50 years and it turns out that Humans just began using more of everything!

Like building roads to reduce traffic and you end up just promoting more car usage! :-)
Nix is capable of that and I consider it golden standard right now, it also allows you do multiple things not related to "package management", such as configuration management, creating vms / docker images, cross-compiling, reproducible dev envs, deploying to AWS etc...
Am I missing something? Are there details or is that all there is?
I had no idea Pine64 had a smartwatch (and earbuds?!)

I have a Fitbit Versa that's really starting to show its age, I might have to check the PineTime out. I also have a Bangle.js which was a fun Kickstarter buy, but it's a little too chunky (I see they now have a v2 of it now which looks slicker)
> News Ltd bought up regional (small country town) newspapers extensively, to the point that the ACCC got concerned. They then proceeded (if I recall this correctly) to shut them down, and centralise news production with a small amount of local news injection.

Same thing happened in Canada with Post Media. Slaughtered local reporting. Endless go-arounds with the Competition Bureau. Now two-thirds owned by the right-wing hedge fund Chatham Asset Management. Same guys who owned the National Enquirer, famous for Batboy and hush-money suppression of scandalous Trump stories.
Nuclear-Powered Icebreakers
> A few people would admit that the challenge was going from algae growing in the pipes to algae growing on the pipes, where it could not be harvested.

I'm not an expert here but I've done a lot of reading on this.

My understanding is that people really don't have a hard time growing algae, it's just that algae doesn't make very good fuel.

This is evidenced, IMHO, by the vast number of companies that started as algae fuel producers and then pivot to algae supplement companies.

This article goes more in depth on the topic [0].

"One of the biggest challenges was that wild strains of algae couldn’t deliver the high levels of lipids needed to produce large quantities of fuel, said Todd Peterson, the former CTO of Viridos, Exxon’s longstanding and now former algae research partner."

[0] https://www.theguardian.com/environment/2023/mar/17/big-oil-...
We really need to standardize "just wrapping a browser view". Why are we shipping a whole browser when we could be shipping a zip file of HTML with some metadata, and maybe a few tiny native helper utilities?
You say it might be the same for the Z80? I think, happily, the situation there is a lot more open and well-documented.

There are specific sites such as http://z80.info which are good resources to describe the chip. The Z80 was also the main processor of a lot of computers, in the UK the Sinclair Spectrum sold in the millions, and there are an awful lot of coders who started their careers, or childhoods, playing with them. People of my age would be reasonably familiar with assembly and the things it can do.

The fact that the Z80 was also used in consoles also provides another avenue for information. There are a lot of emulators out there which have implementations if not necessarily good documentation.

(On a similar note there's a lot of legacy code out there, as the Z80 was one of the targets for CP/M, which is itself source-available these days.)

Compiling CP/M, Pascal, C, FORTH, and running BASIC on a z80 are all trivial - with the right supporting hardware/circuitry for I/O.
me: smarthome, please turn on the lights.

smarthome: you're late.

me: smarthome, sorry, please turn on the lights.

smarthome: why don't you sit in the dark for a while and think about being late.
I like to think of us (life) as a thin film of goo that happens to grow on a tiny speck that happens to float around a star
Appreciate the links. Fable/SAFE has been something I'm curious about for a while. And I already meant to look at the elmish book but had not gotten around to it.

I've actually gone through most of the Dojo tonight except for the reset button.
His description of the former vibrant economy of hundreds of different companies all consolidating into monoliths (in more sectors than just publishing) makes me think of Internet centralization as kind of an instance of Conway's Law with regard to the wider economy. Where there was once diversity and decentralization, now there are single points of control and single points of failure.

A system that works like this is a bad system.
Pebble was peak smarthwatch experience for me. Simple, straightforward, e-ink display. Super bummed that Fitbit bought them out. My Fitbit Versa is _almost_ as good as the Pebble but it's still trying too hard.
Appstores tend to be platform specific, so you might be more easily answered if you tell us what platform it runs on.
Best video conferencing app I ever used tbh. It just worked. Sad to see it go. Zoom is absolute trash in comparison
Huh never mind before it actually works fine at home, must have been a pesky work network filter against it for some reason. I've never seen our work filters do that before though.
I might have to pick up a Bangle.js2. I have a v1 but it's too big for me.
There are video chat applications for musicians that focus on low delay.

For example:farplay.io .
This attitude is exactly why hiring sucks. You and everyone else want to find your purple squirrel, your Python developer with more years of experience in Python than Guido Van Rossum.

Why is it so hard to accept that the best candidate you will ever get may be someone with relevant but not _exactly_ the experience that you want?
I am replying to confess that I was wooshed and had sent a note to my partner that we should watch it.
A story that could have been written by Lydia Davis.
Google helping with your security is similar to when those nice mafia guys knock on your door offering protection. Don't forget that Google is apotheosis of evil corporation trying to take over all your data. This is the very company that turned "don't do evil" into "do things".
I was a PM at BlueJeans - honestly, I was shocked that we got anything at all for our shares during the sale. It was a great product for quite a while - sad that we got beaten down so badly by Zoom.
Banks already experience a wave of crime. They have mitigations you probably don't know about, and they take the hit. You probably don't face much risk for the bank's shortcomings because of regulation and consumer protection (depending on where you live). If it bothers you switch banks, otherwise don't worry about it.
Facebook AudioGen Demonstration
My wife couldn’t sleep after giving birth to our second kid and it spiraled quickly into full blown psychosis. My wife still can’t sleep right nearly 10 years later.

There’s no shame in taking antidepressants. Some of us have brains that don’t work quite right and we should have more options than “cope” or self terminate.
Almost his first words were: “Well, Dr. Weizmann, we need thirty thousand tons of acetone. Can you make it?” I was so terrified by this lordly request that I almost turned tail. I answered: “So far I have succeeded in making a few hundred cubic centimeters of acetone at a time by the fermentation process. I do my work in a laboratory. I am not a technician, I am only a research chemist. But, if I were somehow able to produce a ton of acetone, I would be able to multiply that by any factor you chose.” . . . I was given carte blanche by Mr. Churchill and the department, and I took upon myself a task which was to tax all my energies for the next two years.

(The Making of the Atom Bomb: Richard Rhodes)

- Chaim Weizmann, then Manchester University, subsequently the president of Israel, on his method of using B-Y Bacteria to "brew" acetone. This very probably single-handedly ended a materiels supply crisis for shell explosives, affected the conduct of WW1 and led directly in turn to the post-war politics of Palestine and the nascent state of Israel.
And then spammers will also leave. Problem solved, one way or another.
I'm out of the loop I guess. Which site would that be?
A bit of boredom leads to “protofeed” (2013)
An unsecured network doesn’t help an attacker gain your TOTP and password unless you’re using a website without HTTPS or that otherwise messes up by putting the credentials as query parameters.

The most an attacker might be able to view is the addresses of the sites you are connecting to.
If you think that’s bad, go look up some SSRI meta analyses. The average HAM-D improvement vs placebo is only about 2 points.
It's a Ponzi scheme in that the money isn't being invested. The money isn't working and earning a return. That's why people suggest private pensions as an alternative to social security as it can put money to work. And there's skin in the game as it's not a Pension fund board member investing tens of thousands of members savings with a single decision, it's you deciding your own future and the level of risk you're willing to take on
Literally go to nixpkgs/nixos areas and ask for who's looking for a job? Well, those folks are going to want to do Nix packaging, so... ymmv. Also, my other comment about Nix in this thread has gone through a rollercoaster so uh, that's sure interesting. Hard to not raise an eyebrow at.
Coastal states also get a lot of rain.

We aren't talking about building fabs way out in Abilene are we?
Nope, no expertise necessary. What I do have an expertise in is risk management however, and the cost of being wrong here is effectively zero, so in cases like that there is no reason to act so cautiously, and in fact it's costly to have such a low tolerance for risk in a situation like this.
I can't wait to be using USB C in 15 years because of the EU.
> took horse meds

You’re still doing that? Ok.

> immeasurably beneficial impact in improving the lives and welfare of billions of people

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043740/
Since when is ad hominem a part of evaluating claims?
My wife suffered from PPD, you can take your opinion here and shove it where the sun don't shine. In the midst of her anguish, no amount of having family support could help her. I wish this would have been available.

Typical HN upvoted bullshit from people who are trying to be contrarian to every fucking good thing that's done..
HTTP != HTML/CSS. You are applying a [Strawman Argument]
> Reimagining the Bioreactor

> The bioreactor was designed for the chemistry industry.

Bioreactors are talked about a lot in homesteading. If you want to re-image it that would be a nice start.

Every house not on town sewerage has a bioreactor and dams are natural bioreactors, there are products to mange these, but they are not tested - https://www.amazon.com/Splosht-Large-Fishpond-Water-Feature/...

It'd be interesting to see a bioreactor for more general waste, like wood and plant matter.

> antimalarial drug precursors

I'm dubious if big pharma has a problem with this it hasn't solved it.
G9.js: Automatically Interactive Graphics
If it isn’t harmful

That’s a big “if” though.
There's always something that people are doing that is considered "engulfing" in a negative sense. I'm sure if you saw somebody reading a physical book, you'd think "how quaint!" but even that was seen as an unnecessary distraction if you go far enough back in time https://archive.nytimes.com/op-talk.blogs.nytimes.com/2014/0...
Los Alamos, not Las. (I grew up there myself, 1st grade on)
It's pretty random. It's not even related to price it seems like. And a lot of that could be solved with pretty basic engineering for only a few dollars.

If it was heat and sweat, then I'm sure they could have included a veneer backed by foam and covered in urethane for not too much money, that would look pretty much the same.

It would be cool to see an IKEA competitor that only did high durability items, by pure engineering. If they can't make it last decades with crappy materials and workmanship, just don't make it at all and leave it to other brands.
This seems to be a C extension so will likely only work with CPython, but since Python is so dynamic you can do all sorts of weird things just using plain Python.
> Be warned, apparently Grub had some kind of problem back in August 2022

Are you referring to this?
https://archlinux.org/news/grub-bootloader-upgrade-and-confi...

This isn't the first time, and won't be the last time, something like that happens with grub, and it's entirely an issue with the user not doing what they should when they run archlinux or some other minimalist distribution that doesn't automate the process of updating grub.

Grub uses a configuration file generator that reads from the human readable/editable /etc/default/grub and creates a /boot/grub/grub.cfg, and the result of that generator doesn't have a stable "interface". At any time, an update to grub might read grub.cfg incorrectly, if you do not generate it again.

99% of the linux distributions out there had no breakage with grub because they run the grub-mkconfig command every time grub is updated through grub-install. It is automated within the scripts included in the packaging of the distribution and the user will never see any of this in Debian, Ubuntu, Fedora etc. If a newer grub package comes out on those distro, the scripts will run both grub-install and grub-mkconfig. There will never be a mismatch between the grub binary versions and the config file state.

Arch Linux users who knew how grub works also had no issue. If you update grub, you must regenerate the config file (it's a "if you update" because arch linux, by default, will NOT automatically update grub at all, updating the package is not the same as updating grub). If you edit the config file and regenerate it when you have a newer grub package installed, you must also update the grub binaries. So any time you do something with grub, you MUST run grub-install, then grub-mkconfig. Doing only one of the two is akin to doing a partial upgrade, which is a no-no.

If, as I suspect, you're an arch user, I would recommend switching to systemd-boot, which doesn't even need a configuration file at all if you set up your system to follow its conventions and use unified kernel images. EFI binaries are automatically scanned and shown in the menu and it uses EFI variables to remember the few settings you can interactively edit, like the preferred kernel to boot. It's robust and only has what is needed in a small, KISS boot manager. It can't even be truly called a boot loader because that part is managed by efistub which is part of the unified kernel image. Very unlike grub, which has the whole kitchen sink, including its own implementation of a ton of filesystems..
Under $100 Pre-Owned Mini Computers to Use as Desktop PC's and Servers
making a few PDFs publicly available doesn't change the course of nature. he is now in the position to fully explain to the world what is going on here as no one seem to be able to reproduce what he claims.

given such facts, it is totally reasonable to question his expertise on the concern subject. you are free to judge people purely based on how much they publish, I totally respect that.
Ffmpeg.app: Use FFmpeg recipes without fiddling with the command line