skysight-inc/HackerNews huggingface dataset:
>"That would be 36.5M$/year although I doubt those kind of revenues are sustainable."

Of course it's not sustainable, but you can certainly recover your investment, plus...a lot more. Then you move onto the next thing. It works if you're making $10k or even $1k a day.

It's a proven model that should be used more often in this "hits-driven", fad-based tech world. You can get cash flowing positively and quickly with a good idea. Not every game or photo sharing app that takes off should be thought of as a billion dollar, world changing business. Sometimes it's nice to provide a few jobs and make some bank.
Funny that you include medicine in the list of luxury things you have to work for. In a large part of the world that's the one thing you don't have to work for.
Misys sold to Vista private equity for £1.3bn
Target killings ended, extortion continues: Malik
This is possible, but consider that a likelihood is definitely not a certainty and that you are at risk of contracting far more diseases with a genetic element than the ones that you will actually contract.

Carrying a gene does not automatically translate into getting a disease or even a significantly elevated chance of getting a disease. That only works if the chance is approaching near certainty, absent any symptoms if you don't use a high enough cut-off you'll be engaging in a high-tech variation of medical students disease.
This is a very difficult area.

Firstly, these consults are never as easy or logical in real life. If you think doctors don't understand Bayesian probabilities then how well do you think patients do?

Decision making when screen positive results occur, with appropriate perspective, is virtually impossible for patients. I've lost count of the procedures I've done for incidental findings found with screening, which we KNOW are benign and will remain benign. Unfortunately, despite very strong reassurance, patients generally want these incidentalomas removed.

Secondly, unless your positive screening test can be dealt with....
a) by a procedure that has zero risk of complications and
b) in a way where no stress is engendered while waiting for definitive results
and) the costs of (screening + treatment) could not be more effectively spent elsewhere
...then there will ALWAYS be negative sequelae with screening. Therefore these negatives need to be assessed in a real world RCT of sufficient size and with maximal control of bias, to make sure they don't outweigh the positives.

Your perfect world of logical patients balancing pre- and post-test probabilities, and acting accordingly doesn't exist.
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This is important advice. There are doctors who train for many years to counsel people and guide them through the decision making process about genetic testing for diseases. However the blog post obfuscates the fact that the kind of genome sequencing available to the public online is pretty harmless, for two reasons:

A. There is no way to predict accurately individual risk of disease based on genetic information EXCEPT for a few rare diseases associated with highly penetrant mutations such as Huntington's disase, BRCA mutations (breast and ovarian cancer syndrome). Even then, taking 23andme as an example, they do not sequence enough of the BRCA gene to provide meaningful results.

B. Detailed risk profiles do not appear important to health insurance companies. You can work this out by the questions they ask you - they are mainly interested in pre-existing conditions. Using blood pressure, cholesterol and family history it is possible to generate a pretty good estimation of the risk of heart disease, but AFAIK an insurance company doesn't care about this.

It is also unlikely that in the future genomic information as it exists today will ever be able to predict risk accurately.

So don't worry. Or even better, don't waste your money and don't worry.
My 2 Co-Founders Are Being Head-Hunted By Apple, Google and Facebook. Advice?
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Well said. This is the real issue at hand here, a level beyond squabbling over simple freight charges.
blog is down?
If you're coming I'd like to introduce a "Show & Tell" this time around. The whole meetup is pretty low-key and informal, so don't be afraid to present the projects you are working on right now. Just stand up, tell what you're working on, take questions & sit down again. Easy! Let's make this a good one!
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> "he US's Saturn V had 5 F-1 engines on the first stage."

Ah yes... but what did the second stage have?

Not more F-1's, but J-2's, which did not even use the same fuel! Compare this with the route SpaceX is taking: http://en.wikipedia.org/wiki/Merlin_(rocket_engine)#Revision...
Without doubt platform-dependent mobile apps: by nature patents expire.
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Please don't sully the term 'science' by association with this drivel.
I'm 100% serious, the deviation between the highest and lowest metabolisms save for people with specific conditions like hypothyroidism is not a significant contributor to obesity.
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If you eat less than you burn, you will lose weight.

The tricky part is in making it easier to eat less than you burn.

Eating healthier food that better sates you inside some kind of structure will help you accomplish that.

Our product will solve all of those problems as well as take the pain out of meal planning even for people not trying to necessarily lose weight.
More than that: the airlines charge what they think people will pay. There's no reason to suppose that heavier people are willing to pay more than lighter people are (beyond children being light and poor).
Except that they have extradited people on multiple occasions.
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For the uninformed like myself, why is this not feasible with the amount of cash they have? Could Apple not acquire a global carrier and mount a hostile takeover of the market?

A lot of people believe that this is the route that Google will eventually go down as they've had a tougher time with carrier support than Apple. From the outside it seems logical to eliminate a market should it pose opposition and if money and logistics were no issue I would think that it'd be an issue of when, rather than if.
In general you don't HAVE TO break your work to tasks and track them. Many people can hold the whole project in the head and that is completely viable strategy. However, small tasks give you a sense of progress. You experience a good sensation when you mark task as Done.

Most likely you don't need iterations. Just a list of tasks sorted by importance is OK. As mentioned, Trello is a very good choice. It is free and visualizes progress. Physical and simple Kanban Board will server as well.
I know you from your previous work, I'll be contacting you when we're ready for beta users outside of our original alpha cohort.

Other people: keep my username bookmarked for future updates, I'll be posting the product on HN once we're ready for more publicity.

Good luck on your weight loss whether you end up a user of our product or not.
It seems it's down... Here is a cached page:

http://webcache.googleusercontent.com/search?q=cache:http://...
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APT Detection with IOCs: The New Maginot Line
But we still feel the flutter of our primal fears for survival, even in the abstraction, and fight to the death over increasingly excessive piles of wealth, as if we might not "survive". And because we do that, in the global picture not everyone DOES survive. If you are convinced you do not have enough to survive, it's very hard to share.

Are you familiar with the 8 Circuit Model of Consciousness? Sounds like you're describing a negatively imprinted first circuit (or "bio-survival anxiety").

http://theuniverseas.com/bio-survival
I use
ReadLater - it is the best way to save interesting articles and read them anywhere
Flipboard and Zite - for random content

However, it is much better to read Books, not articles...
This week-end my father, a pretty good teacher for photography, and I, currently teaching something completely different from time to time, had an discussion on teaching. For me, the main difference between a speach a teaching is flexibility. During a speach, people are listening, but there's hardly any interaction. Teaching is more of a interaction with people.
My standpoint is that teaching more or less means having people thinking about something and learn. A speach can, and should, motivate people to think about the message. But they can live pretty well without one.
In order to teach well, you have to adopt to your pupils on a almost individual basis. Some have to read something to get it, others have to hear it while again others have to see or do it themselves. I guess thats why big classes tend to be that bad for learning progress.

Commin g back to topic / speaches: you have to differentiate the message from the messenger. There are alot of examples of damn good speekers with bad messages, usually with very bad out-comes.
You're essentially saying the same as "if you don't want your habits to be tracked and analyzed, get rid of your habits". I'm not planning to get rid of my DNA (why would I?) - I'm just not handing it over to just anyone, least of all a business.
Good speech and good summary on why I hate people.
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Offtopic: if you are posting to HN, then its always wise to ensure more workers for your fastcgi process :).
I wonder what impact these phenomena would or could have on planets like earth.
Try to run "powertop".
NetZero reinvents itself as America’s first free 4G service provider
But then did not proceed to do so, but instead explained how lack of context in articles generally make them difficult for people to understand. People react too fast before understanding, like most people did on my comment.
Unfortunately, as much as I want to agree with it, the article seriously lacks any credibility. Go claims to present high-level features (namely GC) for low-level system programming. Obviously, this sounds new and ground-breaking. Simply dismissing it on account that "GC is unacceptable [for low level problems]" is nothing short of stating a disbelief: it doesn't prove anything.

If anyone wants to prove any shortcoming, than maybe they should come up with a more technical analysis, or at least some sort of benchmarking.
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VLC Media Player 2.0.1 released, enhanced BlueRay disc support
This article remind me of my first days of C coding and the problems generated with escaped "c:\haracters in strings".

After years I still think that the use of forward slash is the worst decision ever. At least Apple chose ":" on Mac OS classic.
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The article reflects my experience with both Samsung and HTC. Ever since, I'd vowed to stick with stock Android, and when the Galaxy Nexus was released I was quick to grab one. Funnily, after a few days with stock Android, I reached out for CM9 Alpha and found it to be superior to stock Android as well. I think this says a lot about the developers behind CyanogenMod - they are definitely doing something right and that opens up all kinds of opportunities for them.

Regarding the manufacturers: I think they are doing a great job producing better and better hardware. However, given the number of new models they churn out, maintaining and upgrading the firmware for each model is practically impossible. If they do still plan to skin their versions of Android, the only practical option would be to minimize the model churn and ensure they upgrade each model in timely fashion. Otherwise they risk turning off their customers big time.
IIRC screen does not remember your split window configuration when you detach.
Here are the slides: http://speakerdeck.com/u/philhawksworth/p/excessive-enhancem...
They are doing mother fucking rocket science.

I say give them what they say they need, not what internet armchair economists say they need. None of the alternative uses for that money that the US government is finding are as important.
You fail to account for the variables involved in "calories out".

Metabolism is controlled in a large way by hormones. For example, extremely undernourished people will slow their metabolism way down in order to preserve what fat reserves are left. A diet that significantly increases blood sugar will, in many people, cause a high insulin response and cause fat to be stored and only glucose to be burned.

Essentially you're looking at this from the wrong way. For the body to grow in any manner, hormones are required (c.f. growth hormones during puberty). And for the body to have grown, excess calories must have been consumed. What forces people to eat so many calories that they grow in size is triggered by their hormones generally telling them that they are starving, even if they are not. See Metabolic Syndrome, Diabetes, Insulin Resistance, etc.

So yes, calories in/calories out, but you're not even considering _why_ those calories were consumed in the first place.

Disclaimer: I've been eating Low-Carb/High-Fat diet that brought my steadily worsening weight issue to a much more healthy level (91kg to 75kg) through control of my blood sugar and appetite.
Sex is a vice?

It's interesting how much Victorian baggage people carry around... even in articles on the Internet and the economy!
I agree with this. A hard launch date helps to give you focus, and decide what can realistically be achieved by that date.

It doesn't mean that your other features are discarded, it just means that you can get to where you need to be at the right time.

One other thing it does too is give you an opportunity to stand back after the deadline has passed and look at the project with fresh eyes.

For example, at the outset you aim at getting the ting up and running. Then once you are there, switch hats and become a user. Is the thing doing what you need? Are there bit's you don't actually like? Why don't you like them? Would one of your missing features solve the problem? Or, do you just drop that irritating feature?

I think this can only happen if you set the date, execute, and then step back.
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This is a good point, but surely you will agree that we can only discuss where to draw the line, not whether it should be drawn or not?

As said in another post, life is not fair. If we take your point to the extreme, society should even out the disadvantages that come from having below-average intelligence.
"The bubbles are just the natural x-ray results from the electromagnetic z-pinch nuclear effect in the middle of our galaxy."

From: http://www.dailygalaxy.com/my_weblog/2011/02/image-of-the-da...

Not that I agree or disagree. It just seemed interesting from the Electric Universe perspective.

More discussion here: http://www.thunderbolts.info/forum/phpBB3/viewtopic.php?f=3&...
I wouldn't pay TED prices for any sort of generic public conference, and less so if it's going to be available later for free.

But hey, some people do find it worthwhile and they can use their money as they see fit.

In any case I wouldn't care if my money paid for travel expenses or speaker fees. If that kind of thing bothered me I would struggle in my daily life.
“PeerIndex” Picks Up $3 Million, Wins Friends, Influences People (Beats Klout)
I concur with the concurrer and the author with my own more 'positive' addendum:

I just want a cleaned/tarted up C. Something that doesn't make the critical mistakes of Go and Obj-C (adding runtime overhead), but adds optional compile and runtime semantics that can be very helpful and powerful.

Some ideas:

No GC. This is NOT negotiable. I'm tired of belabouring that point.

Give me something nicer than the current C bitfield syntax.

Bounds-checked arrays...optionally. Make the distinction very obvious in the code/type-signature.

Higher-order functions, optionally. I don't really want an object system, just the ability to utilize callbacks in perhaps a nicer way than how function pointers currently function. I'd actually be happy with a standardized syntax sugar for function pointers.

Compile-time (only!) duck-typing and polymorphism. This part I think Go got right, but its sins were too great and the problem it was solving too poorly defined to make up for this.

Unicode-native from the ground up.

Clean up the string/array/pointer conflation, adopt the semantics of the bstring library as the default string type for the language, but leave open the door for 'raw-er' string implementations.

Don't reify language types without enabling people to implement their own data structures at the nitty-gritty level.

Cross-OS green-threads might be nice. Let people define their own concurrency models and semantics on top of what the language provides by default though. Same problem as the language type reification, don't delude yourself into thinking you've solved the world's problems with your subset of solutions. Let people use things like ptrheads without punishing them for doing so.

But most profoundly of all:

Make a language that would make writing a library like libev or libevent less bug-ridden and a lot more fun.

P.S. I sincerely hope someone writes a "pragmatist's" systems language like this.
Nonsense. Companies can want to eliminate jobs till the cows come home and write it on their Santa wishlist - whether they actually can eliminate jobs is determined mostly by technology.

In your example, either the company bought new, more technologically advanced digital projectors that actually do need much less supervision and maintenance, or their plan simply failed and they had to re-hire people to run and repair the projectors after they had some expensive downtime and/or management and technical staff burnt out or quit.
I think you put it nicely - you think you're buying a service, this guy is arguing you're buying weight transfer, I would say you're buying seats, and whatever model makes the most sense should be used by the airline company.
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Naive question, but how much of this information could be gleamed by a nefarious source from an aluminum can you throw away or a piece of hair you drop?
>﻿﻿I also see it to arch's credit that I was able to do such horrific things to it with such ease (and fairly good documentation).

This is the key differentiator between Arch and other distros (particularly, Debian): Arch wins when the user wants to modify the system in ways not intended by the maintainers of the distro. In contrast, Debian wins against Arch when the user never does anything that the maintainers of the distro did not anticipate that users would do. (Debian wins here because changes have gone through vastly more real-world testing and bug-fixing before hitting Debian stable than they have gone through before hitting the machine of the Arch user. Note that there is no stable version of Arch Linux.)
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I loaded up the S&P 500 into the equity screener on the Bloomberg terminal and got a sum for the cash and marketable securities column. (Apple correctly shows 96.7B in the column, so I know it is comparing apples to apples.) The data comes from the latest filing of each company.

edit: I see what they did. The bottom chart is showing cash from operations, which is a totally different data point. That chart is old (2011 Q3).. the cash from operations value for the S&P 500 is now 1.65T and Apple is 45.31B, or roughly 2.75%.

Their "Top 10" list is wrong by either metric. The 10 companies with the highest cash and marketable securities (what they are showing) are:

JPMorgan Chase - $380.20B
Bank of America - $357.29B
Berkshire Hathaway - $162.47B
Bank NY Mellon - $135.25B
General Electric - $131.87B
Apple Inc - $ 97.60B
State St Corp - $ 68.12B
Wells Fargo & Co - $ 63.81B
Goldman Sachs - $ 56.01B
Microsoft Corp - $ 51.74B
Apps Going Freemium: Games Playing into Game-Makers' Hands
If you're referring to \ it's a backslash not a forward slash.
The early DOS developers wanted to use "/", so it turns out the underlying OS will accept either / or \. The main trouble you have is that cmd.exe and powershell think \ is the switch character -- so as long as you're not writing programs that write shell scripts or shell out you do OK.

Back when I was a Windows dev I drove the guys I worked with nuts because I used "/" instead of "\", figuring it would be more portable and I wouldn't have to write "\\" all the time. Of course, C# has @"" just to deal with that latter problem.
Now make a Javascript implementation and I'll be forever grateful.
https://news.ycombinator.com/item?id=3469692
>"This is when I realised that the old myth of "as old jobs disappear new ones will take their place" wasn't true. The company had no intention of generating new work"

The jobs are very unlikely to be created at the point of elimination. The theory is that the jobs will be created somewhere else. And remember, somewhere else is now global.
Do you seriously doubt that the Go GC is significantly worse than the Oracle JVM GC (by the metrics of pause times and throughput)? I don't think I've ever heard anyone suggest that it isn't.

My point with this article is simply that, even if Go's GC catches up to the JVMs (which would be an amazing accomplishment in itself), it would still be too inefficient for serious systems work. I provided several real-world examples to that effect.

If you want benchmarks, check out the numbers from moving some of the critical allocations off heap (and out of the GCs reign) in the Java HBase project: http://www.slideshare.net/cloudera/hbase-hug-presentation
it would be nice if you could announce it one week in advance next time :)
That's a limited OS (legally, not technically) - an evaluation version, to be precise. "Don't want to buy Win7 (right now)? Buy Win8 (in a little while)!" just substitutes one expenditure for another (IANAL, but it doesn't look like you could use an evaluation version of Windows for an unlimited time).

But getting to try IE10 and IE10metro is useful, I agree.