skysight-inc/HackerNews huggingface dataset:
I learned to code solving mazes! :)

I would also add to this list: controlling room light colors or modifying websites you visit.

For people new to code, seeing results immediately is very important. All the theory, printlns, etc, it can be hard to see how it's useful.
This is a demonstration that hard work isn't useful work, since the LHC is just spending infinite money on finding things we already knew.
FCC prepares $75 monthly broadband subsidies for “high-cost” areas
I didn't mean to suggest that the two phenomena were connected, sorry!
NAT is a bandage over a crippling of proper network behavior. You trust your port forwarding isn't illicitly opening itself, no? Then you can trust a default deny inbound policy on IPv6.
I don’t think this is targeting a mutated version of PCNA… that would assume that all cancers had the same mutation.

Instead, this would target both healthy and cancerous cells. However, the idea is that the cancer cells are more susceptible to the drug. Healthy cells will be affected, but cancer cells will be affected more, and are more unstable, so losing PCNA will have more of an effect on the cancer cells.

The main idea is to do as much damage to the cancer cells while doing as little to normal cells as possible.

Edit: after reading the paper, the drug is targeting a cancer specific isoform of PCNA. This isn’t a mutation, but a slightly different form of the existing protein. Cancers tend to rely on this specific version, while healthy cells can use a different isoform (or both?). A selective inhibitor for this isoform would be cancer cell specific. There would still be some effect on healthy cells, but not as much as with a traditional cytotoxic chemotherapy.
This is just people understandably getting excited about a huge discovery. What type of people would we be if such moments didn't get us going?
This would be normal. A person who is not confident is very unlikely to make a comment making a prediction, so most of the comments you do get are very high in confidence, regardless of any actual facts or contexts.
polkit does not require systemd.
I originally went to blank keycaps to break myself of ever looking down to type, I was a decent touch typist before but doing that is “next level or bust” move.

That was years ago, but I kept it because people seem impressed by it.
Agreed--every software engineer I know loves deleting useless code.

But this is not incompatible with refactoring instead of rewriting.
I try to watch this once a year or so, or when I'm feeling down:

https://youtu.be/Qeprj9vPtSM
The illegal part wouldn't be putting the chems into your body, but selling or giving such chems to someone when you know they're planning to ingest them
To me it seems similar to sharing Netflix account passwords... which Netflix is now cracking down on.

You're allowed to use the service/software but not allowed to take away new business clients from us by re-sharing the source yourself.
If there were an HHKB or Tsangan layout keyboard module for Framework laptops, first party or otherwise, that'd make them significantly more appealing to me when laptop shopping. One of the main downsides of becoming a keyboard enthusiast and finding a layout that really "clicks" with you is that you're stuck with standard layouts on laptops.
It's a precursor to a hormone. And whether it's a vitamin depends on your sun exposure.
No mention if it affects fagus sylvatica (European Beech)?
You’re misunderstanding me. RHEL is saying that to be/maintain as a customer, you have to not redistribute the received product, correct?

So, again, to become a customer and receive a product where the license of that product dictates you CAN redistribute, you MUST first enter into another contract that says if you redistribute the product, it may violate your standing as a customer and jeopardize your chances of receiving any future product.

Of course it’s a loophole, and I really hope it gets to court somehow because I doubt it would stand up. Just my opinion. I don’t know anything about GPL law, but it doesn’t seem logical that this is something that would be able to stand.
The 6809 was my favorite 8 bit CPU to work with. Two of them would be even better!
My port forwarding would have to actively try to allow traffic to my host. It doesn't even know where to forward to. And like it or not, NAT has momentum. Getting rid of NAT would be a big migration in of itself.
I struggle with this too. My usual exercise routine is to run alternate days.
With WFH, I go on 1 hour evening walks on days I am not running. This makes up for the lack of walking at home.
That's going to leave a big hole in your CV/resume where there could be a CNCF word salad to make the recruitment and HR drones drool.

They need to know if you can write a custom k8s controller in Clojure to generate cronjobs that run k8s jobs that call AWS lambada to ingest data from elastic cakehole and inject it into substandard-IA random availability zone iceberg storage while a Annoying Notification is triggered via ANS to a Rickety Queue Storage sent to someone via Shaky Email Service that eventually ends up in someone's Junk Mail folder in O365 but contains a link to the insecure bucket with the entire company's payroll data in it.

Btw if anyone wants to hire me to wire stuff up like this and help you piss away money you don't need into Bezos' pockets, please get in contact.

Edit: incidentally this is why I'm breakdown level done with all this shit and am going to do something else with my life.
I don’t know of a way to get one that doesn’t involve a lot of DIY.

There are multi-layout PCBs that can support a unix69 layout, eg https://mechboards.co.uk/products/65-pcb but they all require soldering, and you also need to find a suitable multi-layout switch plate.

I designed my own PCB and enclosure, mostly for fun. I will publish it but I need to make sure the custom KiCad library footprints are committed to the right git repository…
Right. Even though we provide support for both OS models and custom ones, this part of the framework lacks proper maintenance. In this case less was definitely NOT more, and it's something we're aware of.

To briefly present our current solution, the idea was to mirror API behavior. We're providing a local host to which you make "calls" (symsvr). Behind the hood, that's just a wrapper around huggingface for casual and seq2seq LLMs, or a custom interface which the user has to implement for its own model (i.e. inherit from our Engine base class and implement the needed methods).

Initially, things were a little bit easier with gpt-j-6b, which we used to bootstrap, but things got a bit messier since LLaMAv2. Please expect in the near future the framework to come directly with OS models: LLaMAv2 for the neurosymbolic engine, a local indexer (we think of using Milvus), and a local embedding engine.

We welcome contributions. Please make PRs.
Yes, but IPs are more ambiguous than hostnames in many cases.
> If everyone is on the same page and have the same motivation then there is no manipulation.

Or the manipulation was very successful. The 401k system manipulates the working class into supporting capital class causes: through injecting liquidity, supporting policies that boost share prices, and being unsophisticated investors who never pull out of downmarkets (i.e. bag holders)
Honestly, I do not remember. A few years have elapsed. I did not do so in any thoughtful way - there was a supplement in pill form and I took it in the evening. Pretty much the only time in my life I self-medicated with something. I would say just observe how it makes you feel, keep a diary? At least out of curiosity rather than caution. If you find it makes you feel better then that's great. (Of course subjectivity is a problem in this case).
I don't know why your comment was marked as dead, vouched it as you make a good point.

The thing is, debt isn't bad per se - having a strong rail network can actually enable far far bigger returns. The US is the perfect example actually... railroads were what enabled "going west" from the East Coast where the European settlers landed.

If you have a strong rail network, you can move a ton of goods (or people) with barely any emissions, leagues better than airplanes, cars and trucks - only ships have a better efficiency in fuel consumption/CO2 emissions per passenger/ton kilometer. And rail infrastructure can hold up insanely long... here in Germany we're still using signalling systems and rails literally built way before Hitler, before the first German democratic government, back when we still had a Kaiser. Spread the 900 billion debt over 100 years lifetime and whoops, pretty cheap, isn't it?
If it costs pennies a pill and you are trying to sell it for a million dollars, that is a surefire way to get murdered by a mob. I would just sell the patent to the government for a hefty profit and be done with it.
It seems like a great way to allow a system that it's known to exploit desperate people to do so selling all kinds of miraculous treatments that don't have to even have a relic of science on them.

Having cancer already sucks enough, having businesses and whatnot vulturing over your condition to sell you shit that doesn't work wouldn't really make it better?
"This was thought impossible"

By who?
There is compassionate use: https://www.cancer.org/cancer/managing-cancer/making-treatme....
I pay $70mo in Portland for 1gbit
What I think was really happening was that customers who subscribed were:

- subscription for some core systems

- centos elsewhere

I suspect redhat is just going to continue to bleed customers.
And keep them in groups of 4 so I can easily and deftly land on F5 and F8, which are to the extremities of the group.
It has appeal for kids (I loved it as an 80s child) but it was created, written, and performed by a group of comedians with SNL and other sketch comedy backgrounds. It also has a scene that implies Dan Akroyd is receiving a blowjob from a ghost.
That's not relevant to the point, since it's analogous to them choosing not to do business with someone because they redistributed the software. The motivation is not a point that's in question.
> Well, China has built a shit ton of high speed rail across their country. There is nothing preventing the US from doing just the same.

It’s been discussed many times. China simply does not have to deal with with unions, labour laws, land ownership and such. I don’t think we want to live in such system.

> A 300 km/h "classic" high speed rail like the German ICE will take 13h, but hey even that is manageable.

No, it won’t. There will be scheduled stops, weather, slow sections, accidents.

I used to take Cologne to Utrecht for 3 months once a week return travel. Only once I arrived in both directions on time.
Please elaborate how it's better in person?
Remote:
I can see and hear the person.
I can see their screen.
I can copy past back and forth (as can they) through the screen sharing app.
I can invite others into the training pretty much instantly.
I can send links and commands typed properly in the chat.
User can record session for later.

In person:
Usually have to face the person or the screen, can't see both.
I have to write down commands and pass them, or type them myself.
There is a delay finding others if we need to talk to them.
More chance to transpose commands incorrectly by the user.
Harder to record the session without losing parts.
There is also bahncard 25 and 50. It basically means how much of a percentage you get off the ticket price. Bahncard 50 first class is quite good if you travel a few times a month. Soon pays off and first class is usually not bad..
To prawda. Spróbujmy umiędzynarodowić polskie nazwy :)
I don't use gen_statem, its clunky as hell, does a weird thing with response aliasing, and it's even harder to read than Genserver. Plus I don't need it.

I understand why the callbacks in gen_statem are so messed up though, they want you to be able to organize your code by state. Since Erlang and (weakly) elixir requires you to group handle_x callbacks linearly in the module, you can't group by state unless you have a `handle_anything`. It's all so messed up :(
Not much. I had a NeXT cube and the user + developer experience on my M1 Air is largely the same. More portable, obviously, and more colourful. Faster, but not nearly as much faster as it should be, IMHO. Well fortunately I write very little Swift, so at least compile performance is OK, and a lot of the user-noticeable speed improvements come from SSDs.

> video streaming

NeXTStep had NeXTtime, which IIRC was also important in sealing the Apple deal, as Be's big claim to fame was (multi-media) performance, with the for-the-time impressive demo of 4 videos playing simultaneously. Nobody had really thought of it before, but playing 4 videos was also not an issue in NT, so Be-blocked.

https://www.paullynch.org/NeXTSTEP/AppleNeXT.htmld/present.h...
I now live in Luxembourg and public transports are just totally free: buses, tramways, trains... All free, for everybody (locals and tourists alike). No pass, no nothing: you just hop in the bus/train/tramway and you're good to go.

You can also rent public bicycles and they're all e-bikes/pedelec and they're very cheap (but not free).
This kind of contribution is completely unhelpful but yeah great for harvesting upvotes I guess.
Didn't Twitter[1] actually die after Threads launched, though?

[1]: The brand, as Twitter Inc. was merged out of existence back in April.
> You design it properly

And how, if I may ask, does one design it properly?
Rise of AI newsbots shakes up India's media landscape
Sorry, but that is complete babble, in the vein of ChatGPT output. Nice engaging!
Even if it were $250, that's a pretty high cost relative to the annual cost of insurance. It's too high to justify as a routine diagnostic tool. The financial benefit here is that earlier identification would save money in the long term treatment. MRIs don't cure cancer, so the direct benefit only applies to the limited savings on a very small subset of people of the people who actually get cancers that could be identified earlier.

The real benefits are indirect (from the viewpoint of the insurance people who unfortunately pay for it)- quality of life is much better if you catch it earlier, and the medical research benefits are huge.

Realistically, it's also not $250 even outside the US- not for the resolution needed to diagnose cancers. That's below the depreciation cost of a high end (say $1M) machine. 12 scans a day (it takes roughly an hour for an average scan, 12 is per day per machine is pretty average[1]) 7 days a week for 10 years is 43,800 scans. So ignoring interest, labor, and absolutely everything else that's $228 per scan.

A full body MRI takes an hour only for small patients. More realistically 1.5-2 hours.

[1]: https://www.auntminnie.com/index.aspx?sec=ser&sub=def&pag=di...
If you have the ability you can try changing presence_penalty and frequency_penalty.
Hundreds of new brand names on Amazon will include 'LK99' in some way.
> we have already set the standard that government can force someone to do business with someone else

You really don't want to go there. There's no reason to single out civil rights law when there are all sorts of other examples which are less contentious and less narrowly focused.

For example, common carriers provide a "service to the general public without discrimination" (quoting Wikipedia), where "discriminate" has a far broader meaning than a dozen or so protected classes of most civil rights laws.

Like, the phone company can't restrict people from having a conversation in ancient Egyptian, because they lack a compelling reason.

And common carrier law has existed for centuries.

But that's beside the point. Quoting https://www.ftc.gov/advice-guidance/competition-guidance/gui... :

] In general, a seller has the right to choose its business partners. A firm's refusal to deal with any other person or company is lawful so long as the refusal is not the product of an anticompetitive agreement with other firms or part of a predatory or exclusionary strategy to acquire or maintain a monopoly. This principle was laid out by the Supreme Court more than 85 years ago

The example is almost directly relevant:

] Q: I own a small clothing store and the maker of a popular line of clothing recently dropped me as an outlet. I'm sure it's because my competitors complained that I sell below the suggested retail price. The explanation was the manufacturer's policy: its products should not be sold below the suggested retail price, and dealers that do not comply are subject to termination. Is it legal for the manufacturer to cut me off?

] A: Yes. ...

You wrote "being forced to follow the contract you agreed to".

That makes it sound like you know little about B2B contracts.

The law right now says forces you "to follow the contract you agreed to." You can be taken to civil court if you do not. So you proposal doesn't change things.

Further, literally every contract I've signed has a termination policy describing how either side, at their own discretion, can terminate the contract.

All Red Hat needs to do is terminate the existing contract and offer a new one. Those that don't want the new contract no longer have a contract. Totally legit.
As someone who does this regularly as a code club volunteer I'm not sure I see much useful advice there. Honestly the biggest challenge is accepting that within a group of kids the same age there'll be enormous variation in ability and motivation to pick up learning how to code. And what I have no real insight into is whether it even makes any difference in the long run (i.e. how many of the kids that do the whole course go on to make programming a significant part of their lives, or even if they don't, have it genuinely help them in some way).
Still, I know I only got where I am today because my Dad sat down with me at age 9 or 10 and introduced me to programming - something obviously not all parents can do - so hopefully at least a few of these kids will get the same benefit.
I think I left out important context here.

I rented both for a week during July. The weather was worse during the Hyundai rental; it was in the 30s with high humidity, while the Model X struggled in the mid 20s. The range I quoted was from the app in the car itself, and borne out by real world experience. I can upload the screen if you'd like, or you can take my word; two supercharges from 20 -> 90 were needed to go from Montreal's south shore to Ottawa, using the highway 30. This was more than an hour of waiting the second time around, in an empty parking lot.

Even as an SUV, it was a disappointing experience. My luggage fit easily into the Hyundai, it was impossible to put more than a stroller into the X. Imagine having a family car with child seat hooks — and barely enough space for a one-person stoller. My Timescar small car rentals in Tokyo were way better

To get it out of the way, I don't have Elon Derangement Disorder, and have no feelings towards him, positive or negative. I like Tesla, regardless of anything, because they pushed the ball forward on electric cars. My friend's Model Y does not have the issues I outlined.

However, based on my experience, the X is a low-range impractical car and unusable for large families, even in summer. I wouldn't trade my used gas-only 2016 Sienna for a free new one, despite it being 6 times the price.

On the other hand, the Ioniq held its range, and had great storage capacity. I'd buy it on sight — but it only seats 5. Electrification in my household will have to wait sadly.
I have been a heavy user of KST for interactive and real time plotting but will definitely check this out!
Thank you! We have integration with graphistry, their tool is amazing for dealing with graphs.
Where is the root of trust for package signatures? Who is verifying signatures: the package index or end-users? How do you distribute public keys? PGP is mostly maligned because of its support for old cryptography standards, some needless cruft, and especially the poor usability of its defacto standardized implementation in GPG, but cosign by itself doesn't actually make any of the trust questions I mentioned go away. There are major tradeoffs to be made about who-trusts-who and what that actually means in terms of security beyond just theatre. I'm not convinced that there exists a good trust mechanism that a package index can enforce that actually moves the needle on supply chain security.
Actually some fish living in anoxic environments have adapted to breathing air. Betta fish and Corydoras come to mind.
Even if the hype over LK-99 comes to nothing it became evident to me several days ago that this research has likely changed scientific publishing permanently—and I'd almost bet on the fact if the research is confirmed.

What made this a such a huge tech event with the world watching on was that the research was on a subject that has captured the imagination of both scientists and the lay public for many decades and that it was posted on arxiv.org website which is open and copyright-free, similarly, we witnessed peer review processes also occurring out in the open and in public for all to see—and essentially in real time! Contrast this with the traditional tech journal process, Nature, Science, IEEE Proceedings, The Lancet, etc. which takes months to publish, and is a closed process not to mention papers being the whim of editors who often reject them (and sometimes very significant ones at that).

Irrespective of whatever outcome eventuates, the contrast between traditional, slow and now-very-expensive scientific publishing with that of this speedy, exciting, open and participatory model that's copyright-free will be obvious to everyone.

Moreover, this is happening at a time when the traditional for-profit scientific publishing has come under enormous criticism with Elsevier and others milking the university and scientific establishments to breaking point and the rise of Sci-Hub as a countermeasure. Whilst academics have been aware of the problem for quite some time the general public has not. This research and how it played out on arxiv.org in just two weeks won't be forgotten easily.

If I were a director of Elsevier and after witnessing what's happened in less than two weeks I'd be damn worried.
This Wikipedia article says that it does:

https://en.wikipedia.org/wiki/Beech_leaf_disease

It does not provide a source but this Massachusetts government website that is linked in the Wikipedia article also says that European beech is affected too:

https://www.mass.gov/guides/beech-leaf-disease-in-massachuse...
This sounds very exciting, and I liked reading your intuitive, almost tangible appreciation of the particular molecular structure. You speak of the components like they are old familiar friends! As someone who doesn't know much at all about chemistry or biology, I had what I thought was a very fascinating discussion about your comment with GPT4 which you might find cool:

https://chat.openai.com/share/28d9b203-1cb5-405b-a109-0f5042...

Basically I wanted to see if your comment, along with the detailed description of the molecular structure, could lead the AI to guess how the compound could be useful. I then proceeded to drop more and more hints and asked it to use those hints along with the structure to guess at a potential mechanism of action. In any case, it certainly helped explain to me what you were talking about!
I don't think that evolve is the right word here. It is not that cancers generally will develop to the point where this is no longer useful in humans. In a single human it is possible that some collection of cancer cells mutates in a way that makes them resistant or immune from this effect (e.g.: by not having the mutated PCNA), and so that strain will become the dominant cancer in that one person. It is also possible that this pathway is pretty common, and this drug does not help out much because of that. But because cancer is not spread (outside of some rare cases), this is not really going to "evolve" like viruses do.