skysight-inc/HackerNews huggingface dataset:
From a purely scientific angle, so presumably less amenable to mass production, why doesn't anyone use FT-ICR mass spectrometers to assemble say a unit cell?

There is a good classic primer on FT-ICR, mostly focused on analysis (mass spectrometry) but also mentioning activation energies for reactions and measurement of kinetics etc.

https://warwick.ac.uk/fac/sci/chemistry/research/oconnor/oco...

If you dunk a bunch of chemicals (for simplicity think wet chemistry) in a vial, all reactions and side reactions are simultaneously occuring, so one has little control over what happens on an atomic scale.

FT-ICR can be used to observe the state AND to manipulate the state. Its like having a compact particle collider, but instead of the high (TeV) energy in CERN etc. its just chemical energy levels.

It happens in high vacuum, so low densities of species, hence not amenable to mass production.

But the instrument is both eyes and hands: one can identify the frequencies corresponding to each ionized molecule, and selectively energize or de-energize specific species to encourage or prevent main and competing reactions, by pumping or damping specific frequencies.

One may build up a molecule in elementary steps and eject finished molecules. Those steps can occur at the same time in the same vessel. Its like having a miniature digitally controlled chemical plant, without having to redo all the pipework if you decide to use a different pathway here or there.
I would love to have the ability to define "column groups" in regular Postgres. For example most of the time I just leave the table row-oriented, but when trying to optimize performance of specific tables and queries I could tell postgres to store one or a handful of columns separately similar to a column oriented database. This would allow getting quite a bit of performance out of my database for the few cases in OLTP where I need to do some scans or searches. Even just breaking out some rarely used columns into a separate group could be quite nice for keeping the caches hot.
I guess it’s more like if you cross the line you can’t go to the place where the line is again, which isn’t that much better but it does mean people can legally redistribute it if they are willing to not get any future releases
Justify wasteful things you've done and suggest them to others.

Less cheekily -- it's true that sometimes the best way to research a topic is by writing code that you might appropriately throw away later. And it is extremely important to be able to recognize when something is not worth keeping. But also, often, the most efficient strategy is to think about the problem off-screen enough that you don't subsequently waste time on-screen writing things you won't keep.

It seems strange to usually expect to throw away your first draft. Not every problem is that hard, and even for hard problems, not every first attempt is wrong.
The theory as I understand it is that you have all the expected rights to the binaries you've been provided. But the only thing compelling redhat to provide you future binaries is your contract with them - and exercising those rights jeopardises that contract.

Which technically works because the GPL only concerns the software you've received - it does not concern nor compel the software you've yet you receive.
I think windmill can go a step further if you add the vectordb to the same database https://github.com/neondatabase/pg_embedding
Here's the epub https://files.catbox.moe/wi3lyq.epub
Here's the pdf https://files.catbox.moe/byxfst.pdf

I have the audiobook uploading now but it's just over 1GB. Let's see if HN will delete my links.

Here is the full audiobook in 128kbps m4b file: https://mega.nz/file/LZQjDIBa#ktCd_w70S_s0K467CFtRqUno6Xv07v...
Although I’m a bit sceptic for LLM for complex programming, I really think this will make some quakes in the music industry. Especially regarding mixing and pop music arrangements.
Sidewalks are by far the most space-efficient way to transport people. That's not the problem.

The problem is not doing enough to encourage people to use modes of transportation other than driving.
I largely stopped caring about anything on Goodreads as a signal when I learned how much harassment of authors it enables, in particular fake-review-bombing of books that haven't even been released yet. Amazon doesn't seem to care much, if at all.
Nature is a mainstream science publication which aims for a wide audience, so relatively speaking, it is definitely more sensationalist when compared to the top journals in the respective fields.

Not to disagree with your point. Just that Nature is not a good example to illustrate it.
The one thing I think is great in Windows is the whatever the active apps bar at the bottom is (taskbar?). Hover, get thumbnails, etc. On mac, I find it kind of painful to juggle a few windows of the same application. Can say the same in Linux as well, some apps don't even show up at all, even though they're running in a window/viewport.

I genuinely like and dislike most OS UIs I've tried. They all have things that irk me. While windows settings has gotten more consistent, it's also all the more painful when you had gotten used to the "old way" of doing things and where to look. If MS executives could just get TF out of their own way on some of the stupidity and force-feeding.

Mac, just feels a bit dated at this point, but the touchpad integration across all apps is great. Not to mention the macbook touchpads being second to none in terms of usability.

Linux, I can shift to almost exactly what I want. There are rough edges and spots you cannot reach via UI, but it mostly works without issue. Been using Budgie as my DE for over a year, fairly customized and like it a lot.
Glad they agree but I'd say the street legality of a vehicle is a separate issue from the self-driving level.
I wonder how much of the uptick could be explained by seasonality (if somebody knows some useful data source, please share). Also the 1.8 Mil new customers could very well be just natural flow and not really incremental due to the ticket. In any case - it's a great initiative.
>For example, there is no version of WWII that doesn't involve Hitler wanting to destroy communism by conquering the soviets, and even just that one thing basically means there was no real path to victory.

It's easy to imagine an alternative WWII scenario where the local communist parties took over Germany and fought with the USSR. Stalin actually decided not to support the KPD during the pre war period, seeing them as a bigger threat than Hitler. Even if you think Communism is great, there can only be one Communism to rule them all..
That would be awesome if you could do this. We had planned to create an open source site and seed it with our codes but we didn’t want to take focus off of our product. It would almost need to be done as a wikipedia style site that could be maintained by the community.
The temptation to throw away all of your code - be it a prototype or a "grown" code base - arises often.

Often it is a bad idea. I get it, though, there is an inherent attractiveness in the idea of starting fresh from a clean slate. Except, more likely than not, you'll soon find yourself in a similar situation to the one you started from. The fundamental problem is that it is easy to underestimate the edge cases. Sure, the main functionality is easily understood and straight-forward to conceptualize. But did you remember to think through all the smaller aspects of your software, too?

Perhaps it's easier with a prototype implementation that in fact doesn't have a lot of features yet, but to completely replicate the functionality of a complex piece of software isn't an easy undertaking. Sure, getting 80% there is probably easy, but the last 20% is the part that's easy to overlook when considering a complete rewrite.

Admittedly, there's nothing sexy about refactoring. And often it may seem like it's less work to just simply scrap everything and start over. However, that's fallacy a lot of times.
The first sentence was explicitly about Theranos. The whistleblower, defrauding former US Defense Secretaries, etc. That was all them.
Paper check deposits were mailed for decades, but are now deposited from the mobile app (endorse, take a pic of the front & back, deposit in the app).

Cash withdrawals are done via ATM, just like (presumably) everyone else. My bank refunds all ATM fees (up to some limit that I’ve never hit [looks like it’s $10/mo]).

I don’t have any recurring need to deposit cash; if I needed to deposit cash, I’d have to drive about 90 minutes to the nearest ATM that will take cash (if this was a regular need, I’d find another bank).
Cost ? Anything over 1 gbs let alone 10gbs requires special /extra hardware which is on the expensive side .

If there is no real use , why spend for that kind of gear ?
I am a total layperson in medicine but I try to challenge myself to read Derek Lowes blog posts and comments here from people like isoprophlex who do understand it. I really appreciate the simplicity of this solution - it doesn't need to be customized for each person, it doesn't need years of work on targeting, it's stable, potentially with few side affects of users. I know even this is a long shot but if it works, the power to change society! I imagine that it would even encourage cancer screening earlier for people to make for more effective treatments.

A working treatment for many cancers will bump many more preventable forms of deaths up the charts - obesity, cars, weapons. I hope that people will be inspired to take more significant actions to reduce those when we've tackled these really really hard ones.

And due to the potential low-cost, easy administration, and storage requirements, I am reminded a bit of how antibiotics ended up working in developing countries. Doctors prescribe them for every pain, making them ineffective at best and spawning antibiotic-resistant bugs at worst. I hope the researchers are able to consider this angle (overprescription) before these medicines become a widely distributed thing in other parts of the world.

It's an exciting decade for medicine. I hope that if we don't see the efficacy we want with this one, that more "simple" formulations will come around that do work.
No assumption needed, we have statistics for that. Including on the affect of strategic bombing on moral in Germany. The Nazis were good at recording these kind of things.
It’s not even a rectangle, it’s a parallelogram (both hands move “up-left” or “down-right”). It’s quite baffling
I'm not versed in reading biomedical studies, but I'm curious about this. A successful in vitro test would not necessarily mean that the medicine could overcome other biological challenges such as the blood-brain barrier for delivering medication to brain tumors. Is my assumption correct?
I just linked it to the guy. It's definitely online. epub, pdf, and audiobook.
Keyboard enthusiasts can never get carpal tunnel because they spend too much time switching keyboards to actually type.
Often happens that you can't see the next hill until you get to the top of the current hill
That's a good question. Tech issues are tough, which is why you see lots of friend of the court briefs to explain it.

For FCC matters around net neutrality, there's generally two courts: the DC Circuit Court of Appeals and then the Supreme Court.

And, yes, they deal with it and have clerks to help.

For instance, in the biggest decision about net neutrality, the BrandX case, where the FCC was allowed to determine that Cable companies were Title I information services, DNS is mentioned 13 times in the majority decision.

https://supreme.justia.com/cases/federal/us/545/967/#tab-opi...

And if you find that interesting, I recommend reading the Scalia dissent, where he said that it's totally clear that broadband is a Title II service, and letting the FCC say otherwise was wickedly wrong.
It would be nice if there were more alternatives to QMK/VIA, which is "programmable" but only so far without major effort and headaches.

The Micropython implementation used in the M60 KB (https://makerdiary.com/products/m60-mechanical-keyboard-pcba) is really nice and much more easily configurable, but AFAIK it's only used on that one keyboard kit.
I've felt this, and I agree. It really pays of to do some work on technical discovery, make all the mistakes, see where all the design issues will be, validate as much as possible, and then start again. And the best way to really scope out requirements and get to know the "unknowns" is really to get your hands dirty.

Especially when in comes to business logic and domain modelling, some bad decisions at the begining can cost a LOT, to undo in an iterative matter.

(To clarify I'm talking about the timeline the author proposes of "a couple of days" build the throw away prototype)
I pay $90 a month for 1Gbps up/down fiber to the home. To pay $70 a month for 25x that speed is ludicrous. I imagine I could pay half of what I do or less to get the same speeds.
Didn't see anything in the article about how much melatonin a person would get from eating food treated this way. I sometimes take small doses of melatonin during the summer months when my sleep pattern tends to drift if I don't actively keep it under control but wonder if consuming it through diet would end up making lots of people groggy during the day.
"All it might take is some instagram cancer influencers, a lab in india or china and some darkweb transactions to DIY your cancer away... "

Or DIY yourself away accidentally. But I guess that would make it a tie, since the cancer dies as well...
Aka "Build one to throw away"
Full disclosure, I used to work directly for one of those guys mentioned in the book description.
Honestly, the more reactions I see from certain parts of the community, the more I agree with Red Hat’s decision. And I started from thinking it was a bad move.

Also, see Jon “maddog” Hall’s take from a few days ago:

https://www.lpi.org/blog/2023/07/30/ibm-red-hat-and-free-sof...
We are each individuals. I just know what works for me and those I care about.

That said, I would not discount that it works. Motivation only works for me if it is either overwhelming, or I'm in a good space. And that mostly means only when I'm in a good space.

Getting into that good space requires keeping my shoulds only things I want for a long enough time to condition my brain to the idea. This is hard to arrange, takes a good while to start working properly, and is easy to accidentally undo. It certainly isn't something I can just turn on.
I’m pretty sure you are correct. At least from the way I’ve seen it used (I took cancer biology lessons but it was more on a cellular level)
> So nuke most of the Western World?

This thread is silly. To reduce the world population you don't need to kill anyone at all. You simply look for ways to reduce birth rates.
Ship your first draft. Never rewrite. Go work on the next task.
Long time ago we already had a large lodash codebase, but I remember liking ramdas api design more. Did a few pocs but we never needed it. We did need a lot of fp though. We were on es6 and constantly merging observables. Lodash was a good supporting library for that, but I think the Ramda version would have been a little cleaner.
The original team submitted a paper about LK99 to Nature in 2020, and it was rejected. The editorial may not be interested that other labs research the material, decreasing the number of verification trials.
Actually it’s great. Sure it’s annoying when people take things too far. But society sorely lacks for interest in science and in general things that make us all better off. I say bring on the enthusiasm and just remind people of the importance of being polite and kind towards one another or at least not mean.

A huge win would be this signaling interest in things that make the world better. Basic research and such rely on public funding and we’d all be better off with more funding going to address such problems than the other places funds go.
It’s fun to have sex. Glad I could clear this up for you
The author of the article is a freelance science journalist not really an expert in this space, so I think it is reasonably appropriate to be dismissive of their perspective since they aren't a researcher in this space and probably cherry picked the evidence they wanted for their story.

I'm excited by the potential of LK-99 and I wouldn't be surprised if it turned out to be a red herring, but I'll wait for the scientific community to sort it out versus paying attention to a non-expert journalist who is weighing in so strongly on the matter this early in the game.
Window Snyder, a trailblazer who helped secure the internet
Reread that sentence again. Particularly the words "from open core proponents"
The invasion of the Soviet Union was a losing tactic if, and only if, the Nazis had to fight on two fronts. The Allies had to attack the Nazis from the west in order to make them lose. That’s what they did by bombing.

This isn’t a niche opinion. In the exact same documentary series as I first mentioned (World At War,) a Nazi military official argues that the Allied bombings were successful because they forced the Nazis to split their forces along two separate fronts. They were unable to divert their ammunition, air support, etc to Russia because of the bombings.
If enough people cared, you could probably make the same argument that got sports betting into a place of legality and get at least some subset of prediction markets legalized.

The sportsbook argument was that sports betting involves more than random chance - knowledge of the game, the players, etc. effectively turn it into a matter of skill.

I doubt there are enough interested parties to bother for prediction markets, though.
They are, of course, always free to distribute the source to anyone else. RedHat cannot stop that. But if they do distribute the source to anyone else, RedHat is free to stop taking their money and not provide the software and source code to them in the future.

It's shitty, but I can't see any realistic way to close this loophole.
> nobody burns polluting coal and gas for fun.

Look up rolling coal. But yes, most people don't.
I have found that in general, the simplest thing that works, that is easy to replace tends to be some of the longest lived software I've worked on.
Trying to get to an agent is practically impossible. I called recently to make an account change, but after I went through the automated system I got an "I'm sorry, we see there is an outage in your area. Please wait for the outage to be resolved and then call back."

Insane.
https://www.focusonthefamily.com/family-qa/what-the-bible-sa...

These people do literally believe that. They represent a sizable political faction in the United States.
> I'm not sure if I'm more passionate about tech, more extroverted, more obsessed with improving processes or just less busy than them. It's been like this at multiple companies I've been at so it's not unique to my current team.

It's none of these things. I am the same way but we are the minority.
I think you’re misunderstanding what I’m saying. I want people to have rights in 500 years. And there’s a good chance they will. My point is that they might not.

You might also be thinking that by “rights” I am referring to some abstract ideal about inalienable rights people should or do have. I am not. I am referring to rights in the practical, legal sense of those things your government cares to protect. Well, for a person born into chattel slavery in 1830, you might say they had a right to not be a slave, but in a practical, legal sense no they did not.

You and I both agree that “no utility = no rights” is morally wrong. But it isn’t up to us. It will be up to people in the future.
If the price is under $70 for 25G, I'd imagine most people pay half that for less bandwidth, but the 25G works for a number of people who need or want it, plus is great marketing. Also selling 25G that's underutilized is probably substantially cheaper.
I think there is browser extension potential in here. Would it be profitable, thats the question (and the answer is most likely no)
I think this is a really good analogy for exploring my emotions on the topic.

There are people who make utterances because they want to show they are paying attention, and there are people who make them because they cant stand not being heard. To me, the latter is more distatsefull than the former.

I think it is gross that in the attention economy, the drive for existential validation is reduced to posting "cool" to be seen, and clicking an upvote feels like being part of a conversation. In some sense they are, but it just a very streched and hollow manifestation of human interaction and participation.

My likely arrogant and possibly hyprocirtical conceit that I think what I post into the void is more interesting and substantial than "cool". Still, that doesnt change my feeling on the subject.
Okay so almost useless, not entirely useless
My Redragon K552 has the ESC key at the upper left in line with the dedicated Fn keys. This males it easier to hit when using vi.

Beside "1" is backquote and tilde. Seems to work well.

I should get around to remapping Ctrl and CapsLock one of these days...

BTW the K552 has been able to take a lot of abuse over the years and is still working well for me, and it is not expensive. Cheaper keyboards often don't last a year with me (I learned on a manual typewriter). I think I paid $40 at MicroCenter like 2 or 3 years ago.
I guess there's nothing stopping people from just shamelessly making up data on Twitter even when they're linking the actual article. This is very cool and very promising research but "almost completely inhibits the growth of xenograft tumors without causing toxicity to experimental animals" is not the same thing as "kills 100% of tumors." I do understand that there's an incentive to lie like this on the internet - it's not just magical internet points when people get paid real money as creators for getting clicks, but come on, really? Is it worth poisoning the discussion around some actually incredibly cool and promising research while driving false hope (which can actually hurt people!) Just for a few extra pennies from twitter's creator fund?
That seems to be their theoretical use, much like the downvote is theoretically supposed to be their inverse.

In practice though, it seems that the users of most online communities seem to treat them as an "agree or disagree" button, with dissenting opinions typically being either forced out of a thread or languishing due to the upvote-downvote tug of war generally suppressing a comment's rankings.
> Zig can and does win plenty of those benchmarks, but ultimately it boils down to who is it that gets nerdsniped into working on a specific challenge.

> For example in this case Zig won big time over what C/C++/Rust people submitted: https://youtu.be/pSvSXBorw4A?t=1075

That was a faulty benchmark with a simple unnatural footgun that the Rust people overlooked. I don't think it supports your claim that benchmarks typically boil down to who is it that gets nerdsniped into them. Sure, it can happen, it happened at least once, but in general?
This makes me think of the React patent license issue from some years ago.

React was licensed under BSD, but had a patent license that many interpreted as saying if Facebook sued you (among other things) you'd lose rights to any Facebook patents, including any that applied to React. Having rights under the BSD license didn't override that.

Different situation, but same vibe.
Anybody who thinks Chris Rufo is spot on about anything is deeply mistaken. Chris Rufo is the conservative shit-stirrer who admitted outloud to manufacturing the moral panic about Critical Race Theory for political, not factual, reasons.

That doesn't mean he deserved the treatment he got, but it's telling that his treatment drove him more toward the reactionary and racist side and an example of why, if you're going to come at someone over something like this, you'd better have your accusations in order.