skysight-inc/HackerNews huggingface dataset:
Retroviruses don't have cellular membranes. They could over-express PD-L1 in a cell it infects, but they don't need the cell to live, they want it to lyse and release more viruses (though I guess you could argue it wants it to survive immune attack long enough to do so).

Bacteria could potentially do it, but also bacteria cell walls are very different than human. I'm not sure an expressed transmembrane protein could actually be embedded in a bacterial cell wall and still remain functional.
Stop trying to be productive with your phone
Found the non-parent giving parenting advice.
It's this one:

https://github.com/lachlanmcdonald/hackernews-user-tags
> Just judging by the comments here you seem to be the only user on HN with one

Are you really so inattentive that you didn't see this https://news.ycombinator.com/item?id=37042238? And you could find many more on HN if you actually wanted: https://news.ycombinator.com/item?id=35850098, https://news.ycombinator.com/item?id=29401950, https://news.ycombinator.com/item?id=24959506, https://hn.algolia.com/?dateRange=all&page=0&prefix=false&qu....

Also a lot of people are waiting when these phones become better daily drivers: https://hn.algolia.com/?dateRange=all&page=0&prefix=false&qu...

> Is ist a sizable market

Why does it matter? Every breakthrough starts with a niche community (unless it comes from large corporations).
This one: https://github.com/lachlanmcdonald/hackernews-user-tags
Your assumption is that only small EVs will go through these tunnels in the future. I think that assumption is flawed.

Tesla announced it wants to make high-passenger-count commercial EVs (akin to vans and buses):

https://www.tesla.com/ns_videos/Tesla-Master-Plan-Part-3.pdf

EVs that carry 8, 12, or more passengers (perhaps by chaining the EVs) would significantly increase the efficiency and throughput of these tunnels.

And then there's a big question mark on self-driving, which, if achieved, would significantly improve the economics.
Absolutely. The courts are supposed to be the last vestige of common sense. It’s judges dropping the ball here by letting high power lawyers steamroll their courtrooms with this nonsense.
While this is a real issue, that effects terminals in real-world use, I took issue with this quote:

> This issue affects every terminal I've tested: Visual Studio Code, iTerm2, Alacritty, and Hyper.

I don't think those terminals are particularly known for being feature-complete with regards to VT/ANSI codes or new developments such as emoji. The quantity of things a VT-ish terminal must do is massive and not standardized, so many terminals just cover the common cases and nobody notices that they're incomplete.

If the author noted that emojis don't work properly in xterm (not xterm.js) or konsole, then that'd be something to write home about.

For reference, I've written a terminal emulator fairly recently, and found xterm to be most faithful and also a great source of documentation in itself. In personal use though, konsole is pleasant and seems to do everything I've seen right.
On the other hand, currently writing this from mac and iterm2 is kind of terrible, send help.
It isn't even thinking ahead. It is pure, plain and simple arrogance, of the most despicable and stupid kind. The German auto producers are used to be able to strong-arm politicians and their suppliers. What they say goes, because usually they can threaten whole regions with unemployment and whole companies (the ones that produce car-parts such as seat cushions or engine parts mostly/only) with bankruptcy. Don't want to accept a mandatory 20% price reduction mid-contract? We'll just delay payment until you do, good luck surviving long enough for the courts to recognize your claim...

With chip makers, it is different, because chips can be used in lots of different products and there is lots of demand from all corners. So car makers tried their usual strong-arm tactics and failed miserably. Chips being a sellers market, after all. After which car makers went whining to their politician puppets, getting them to OK billions in subsidies for "supply chain security".
Is that actually true, though? I’m pretty sure we’ve built more than 20 miles of tunnel over that time period in LA alone.
Readers and especially reviewers need to looking at effect sizes. Not just "was the p value under 0.05 so there is some effect". What a nothingburger.

Let's break it down.

> Breakfast skipping was correlated with BMI (Wald, 5.481, 95% CI, 0.154-0.847, P-value, 0.019).

What that means is that breakfast skipping was correlated with somewhere between no BMI points and 1. We have no way of knowing which from this study. Basically, maybe your BMI goes up a little, but so little as to be irrelevant.

> A positive direct correlation was evident between late dinner intake, BMI, and HbA1c (Wald, 4.210, 95% CI, 0.743-0.993, P-value, 0.04 for HbA1c, and Wald, 6.777, 95% CI, 1.0221-1.165, P-value, 0.009 for BMI).

Maybe eating dinner late increases your BMI by 1 point or so. This is probably the same point they claim you gain from eating breakfast late. The A1c numbers are so close to being statistically insignificant that we can just ignore them.

And that's before you add all of the other problems with the study.

This study shows nothing. Yet another questionnaire based study about nutrition. I wish we could as a scientific community just ban this garbage.
Look I had to pick a title that would resonate with people on what they might not want their kids to read. I'm sorry I offended you that people might want to censor the materials a child might read but it's a very common use case, so much in fact that there have been class action lawsuits against companies like amazon/apple/google/sony/microsoft for not allowing parental controls (and not locking the kids out of buying smurfberries).

And yes, as a parent it's part of my job, and my right, to pick and choose what I think my kid is ready for.
While for individual cases clinicians shouldn't rely on BMI much, and only use it for screening, in studies it makes sense to use it because it's a useful tool. A person with a BMI of 30 is almost always fatter than a person with a BMI of 20. The outliers (like athletes with big bones) wouldn't change the statistical analysis.

It's in the same boat with IQ, it's a useful tool if you accept it has limited uses.
Comparisons based on nominal exchange rates are misleading, because the rates fluctuate a lot. The 2008 numbers in particular are not based on the strength of the EU economy but on the weakness of the US dollar during the financial crisis. Back then, €1 was worth $1.5 to $1.6 for a while, while the long-term average is closer to $1.2. And right now, the real year-on-year GDP growth rate in the EU is ~10% (when measured in US dollars), because the euro was particularly weak a year ago.
How much would a 68 mile subway under Vegas cost?
I remember watching his Google talk[0] several years ago while learning vim. RIP and thank you for your contributions.

[0] https://youtu.be/eX9m3g5J-XA
> Aren't LLMs potentially great to ward off language death due to their significant abilities to transpose ideas into different languages?

What do you mean?
Here is some more good info and sharp commentary including how fast this is getting built...

https://www.casino.org/vitalvegas/vegas-loop-experiences-mul...
Show HN: Safely linking out to sensitive 3rd party content
Sometimes linking to 3rd parties can be a risk. Especially for sensitive information. This is an alternative solution to linking to an archived version.
Nextflow: Data-Driven Computational Pipelines
Stability AI launches StableCode, an LLM for code generation
Hand-picked themes that you can copy and paste into your apps
Agreed! multiple times I wasted hours figuring out what selectors to use, but then remembered that I can just look at the network tab and have perfectly structured JSON data.
My prayers for this man who has a big impact in my life. vim was my daily tool in my 15+ years of software development over various operating systems and environments.
> removing any/all sympathy for the striking writers.
Wait, what?
You can say this about any US policy, until it is officially announced. It turns out that the US gov has made all the moves to weaponize Taiwan and make it the center of a war against China, so what is the surprise that they will bomb Taiwan if needed?
Unpacking Amazon’s stealthy mass layoff strategy in Seattle
This isn't the typical 1000 word, "here's how we did it, now use our thing" company fluff blog post. What a great writeup. Sometimes reading docs, it is hard to figure out the fine details when making a decision. Your comparison of Regional Tables, Regional By Row Tables, and Global Tables is a really nice summary of the pros & cons of each. Well done.
> It’s judges dropping the ball here by letting high power lawyers steamroll their courtrooms with this nonsense.

See also: [0], sometimes it may not be judges "dropping the ball" but rather playing the ball for their own benefits.

However we spin it, corruption in the US is a larger problem than we like to pretend it is.

[0] https://www.propublica.org/article/clarence-thomas-harlan-cr...
Littler Books: Top nonfiction books summarized into their essential ideas
Ah, damn. I've seen this guy's name almost every day for my entire career, every time I open Vim to jot down some notes. Reading his website about his financial support and visits to Uganda was one of my very first introductions to the open source software community as a teen in the mid-2000s, back when I was still using Windows. RIP, Bram.
why create a backup branch instead of just pointing the rebased branch back at the original commit?
Spot on. And let's be honest even at the individual level - you know whether your BMI is "high" because you are a muscular jock or just an average joe that (over)eats the wrong things and is a couch potato (same probably applies to the ultra-lean runner types on the low side).
The market for Pinion bikes with belt drives is driven largely by bikes in Western Europe bought by families that need to transport children and shopping. A second market is people wanting a high-end bikepacking bike for expedition cycling. Those families and bikepackers are usually willing to spend several thousand euro for such a bike, so there is not yet the strong demand for low-entry bikes.
Depends on the region you're in but non-competes vary wildly in enforceability. They mainly survive on the threat of incurring costs of a legal fight rather than likelihood of actual follow through enforcement.
1/1b of the distance between the North Pole and the equator.
This is self reported data which tends to be really bad data for obese patients.

https://sci-hub.wf/10.1056/NEJM199305203282014
It speaks volumes about American law enforcement that this behavior doesn't just get a cop immediately fired:

Reyes sometimes supplements his own video with police body-camera footage of the encounters, obtained through public records requests. An officer in Danbury, Conn. was suspended for nine days because of footage in which he says Reyes would have been “dead” with his teeth knocked out if police had encountered him in an earlier era.

An attempt to infringe constitutional rights combined with a death threat. Take a few days off!
Research like this is much less interesting considering the revolutionary impact GLP-1's are having on obesity related diseases, and now heart disease too:
https://www.nytimes.com/2023/08/08/health/wegovy-obesity-dru...
Dude, if you think the ROP is bad... don't know if you've seen the Foundation from Apple TV, but holy hell.
Kinda follows the plot, also completely demolishes it in other ways. Mad times
It is for studies because, the average person with a high BMI has higher body fat on average.

That might not be the case individually but with multiple people the few outliers don't matter.
> People who don't understand what OP just wrote should look at what just happened to the South Korean semiconductor market. over 36% plunge in exports[] and that samsungs memory profit dropped 95%.

Is demand for electronics finally dropping? I want to be able to buy a 3 year old Nvidia low-range GPU at below MSRP...
- Split keyboard saved my wrists fifteen years ago, still do every day

- Sleeping mask with eye padding so I can open my eyes without my lids touching anything and only see total darkness. Took some getting used to, but it's amazing for getting better sleep

- standing desk setup with footstool and taller chair so I can just slide off to stand up. Makes it easy to switch so I do it more

- quality earplugs with a keychain case so they are always with me

- injinji ankle high hiking toe socks. I wear these every day now, so comfortable

- instant pot, almost all of my cooking is in this

- old cast iron skillet from a garage sale, if it's not in the instant pot it's in this

- floss holder, saves a lot of floss and is easier to use, so I floss a lot more

- bidet for toilet

- a great pair of four way stretch workout shorts. I got a Lululemon pair at a thrift store that has a hip phone pocket. I've worn them for thousands of miles of hiking and they look brand new. Love these shorts so much.

- Sun hoodie, because I'm basically a ginger and can't take that sun. The hoodie keeps me from burning.

- ultralight umbrella, fantastic for hiking in the sun or the rain

- music lessons, I wanted to learn violin and it's easy easier with a fun teacher

- bone conducting headphones (shockz). They are awesome for hiking since you can still hear everything (unless it's raining, then they are annoying). I love wearing them in the shower, music while I clean. Since they don't cover my ears, I've worn them for several days without noticing. They are very comfortable
Kids cannot use foreign language tools to their full abilities. However, if ChatGPT is good for english only, it might stimulate some competition for providing similar service in the local language. I won't mind it, tbh.
Several hundred million dollars at best gets you a mile of subway in an American city: https://www.vox.com/22534714/rail-roads-infrastructure-costs...

Experimentation with alternatives is desperately needed.
The main point is that "You agree" is the customer, not the end user.

Which means that in the case where Zoom is provided to you by your employer, they claim that the employer consent is just what matters. Once more "Fuck GDPR".
F1 Demands Las Vegas Venues Pay for a View of the Race
Another great resource for that is "The Bicycle Wheel" by Jobst Brandt. Oops. I guess it's out of print as copies on Amazon are going for $35 and up. My local library should have a copy as I managed to buy two and IIRC I donated one.

Not to take anything away from Sheldon Brown. I've spent plenty of time on his site. And of course Brown has a page about Brandt: https://www.sheldonbrown.com/brandt/
> Rohloff is beautiful but I think it is overpriced for what it offers

Rohloff hubs are made in Germany by a workforce that enjoys good working conditions, and moreover each hold a stake in the company. That’s something to remember any time you compare the price of a Rohloff hub to an Asian-made component.
yeah... but the likelihood that you have a high BMI because you're just so jacked is low.

It's not perfect, but it's a good metric.
A bit of a tangent, but a long time ago I was kicked out of a Facebook group for what I considered to be completely made up reasons -- and what really got to me was that by being banned from it, I couldn't even point to the posts that had been actively misunderstood and distorted. I couldn't find anything in the cache files, so I saved a process dump of the still running Firefox and stitched the posts together from that. I stopped caring the as soon as I had my proof, but was still sheepishly proud that I managed to get it.
> Sounds like systemd stuff. Why deal with systemd.

Because it's better. Because it logs stuff separated by field, doesn't have problems with unusual characters or newlines, supports cursors, deals internally with log rotation and compression, a whole bunch of cool stuff.

> Use Apache customized logging as the parent comment suggested.

That's exactly what I want to avoid, for reasons explained in my original comment.
your body handles glycemic load better earlier in the day. IF + front loading meals is a good recipe for improving metabolic health.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213043/
Power of Fragments with GraphQL Codegen
> catena, "chain", which survives in the word "concatenate".

Survives also in the actual italian word "catena", i.e. chain :) typically used these days for bike/motor transmission chains.

We wouldn't use "catella" as a diminutive though, but rather "catenina" or "catenella".
Nothing shows the power of unions more than the lengths companies go to fight them.

In a Union there is Strength.
12 people would be about 5% of the capacity of a single NYC subway car: https://en.wikipedia.org/wiki/R160_(New_York_City_Subway_car...
Complication is not a typo here btw.

"A complication is an element on the watch face that displays information or allows you quick access to an app by tapping on it."
I don’t get the distinction. An application’s domain model always has an interface layer. It can either be API or UI, but in either case it’s something your model allows to expose.
Pretty much only true if you are a body builder or someone else with an unusual amount of muscle mass relative to your height. For the vast majority of people though BMI is fine.
e.g. https://finance.yahoo.com/quote/AMSC

Which is indeed down today
Hey, this looks great! The only thing I miss is an option to add multiple destinations or search for gas stations, shops etc on an ongoing route.
Like, 2 or three rich men I guess.
This is devious and hilarious. I fully expect to find it in the wild.
> What we need to look at is how much trade has risen between Mexico and China

Total trade between America and Mexico rose from $613bn in 2019 to $779bn in 2022, an increase of $166bn [1]. Total trade between China and Mexico was $100bn in 2019 and 2021 [2][3]. America's trade with Mexico in the last three years grew by more than Mexico trades with China altogether.

It seems unlikely that Mexico's trade growth with America is being driven by playing middle man to China. (Keep in mind: Mexican manufacturing wages are lower than China's [4].)

The contrast is particularly poignant today, with China's announcement of a surprise July export decline of "14.5 per cent year on year in dollar terms...the steepest fall since the outset of the coronavirus pandemic in February 2020" [5]. Mexico, meanwhile, seems to be fine.

[1] https://www.census.gov/foreign-trade/balance/c2010.html

[2] https://journals.sagepub.com/doi/full/10.1177/18681026211038...

[3] https://mexiconewsdaily.com/business/exports-from-china-to-m...

[4] https://www.china-briefing.com/news/reshoring-from-china-to-...

[5] https://www.ft.com/content/6318c973-1ff7-44b6-9f4b-177e0706f...
I've never found ChatGPT to generate a ton of useful code. Anything it can write for me will be too general to be useful (it doesn't have access to my company database). I use it more like a customized stackoverflow and I ask it more general questions to learn from the answers. I wouldn't trust these things to actually write code
I'm always amazed at the stark differences between UPS drivers, and Amazon drivers.

UPS trucks are always clean. They follow the rules of the road. The drivers wear neat uniforms, they walk on the sidewalks, they're polite, they're just professionals held to a higher standard.

Then there are Amazon drivers. They park blocking half the road, music blasting, the vans usually look like they haven't been washed in a month, most of the time it's not even an Amazon marked van, it's just some generic white rental. The drivers often don't have Amazon clothing, maybe just a hi-viz vest, they walk through your grass and plants, lazily toss a package on the porch and walk away.

Reminds me of fast food employee who simply hands your meal out the window, no greeting, no thank you, no smile...
I noped out when you have to take the ISI to continue any further and then the only access to the results is via email (and wasn't a fan of the prechecked send-me-spam checkbox).
Show HN: Generative News Terminal
Hi HN, The Daily Intelligence is our latest take on news curation. You get the latest news summaries, signals and analysis from 45+ sources in any topics, purely generative.

We ran a $1/ month experiment 2 weeks ago, which you can check out what we have learnt here: https://www.reddit.com/r/startups/comments/154ustd/my_1_mont... (we have increased the price to $2 since)

Open to feedback so we can improve the product better!
The headline and article are a little misleading. It's not that all these species "live underground", it's that they rely upon soil, like the vast majority of plant species.
They were never going to be drafted.

We're talking about business owners, professionals. Folks who can easily afford that fee.
Are US bank employees prohibited from discussing financial matters using anything but official channels (email, paper?) per se OR is this about using other channels and failing to preserve records of the conversations?
The nice thing about this situation and one that is not appreciated by enough people in the economy is that it's not a zero sum game.

Two things can be true at the same time!
Maybe because they replaced lots of social security features by private company insurances.

Health care and pensions cover hardly all your needs and need to be supplemented by private insurances.

They privatised or try to privatise essential services like postal services, telecommunications and railroads.

They got rid of government experts in favor of external private company "experts". In combination with construction contracts being put out to tender this leads to failures like the BER airport.
All these private companies weren't able to built and airport that complies with the building regulations. So they either aren't as effective as neoliberlism claims or they exploited the lack of governmental oversight to get more money.

Not to mention the millions politicians like Ursula vin der Leyen gave to companies like McKinsey to advise on the modernisations of the Armed Forces which lead to the opposite.

They are neoliberal, it's just isn't so easy to sell it to the people as something positive. That's why the SPD was needed to implement a wage raise killer like Hartz IV, because people thought of the SPD as a social party working for the workers.
I only used it once for a class in grad school, but it’s things like this that make Swift feel like a really well intentioned programming language, especially paired with the xcode ecosystem.
If you have a single product that kills people, you aren't legally allowed to put all your liabilities and none of your assets into another (non-shell, by your definition) company to get out of your liabilities. [0] What's happening here is quite similar.

[0] See, for example, the J&J case, which was an even more generous form of the same.
This looks like an argument against enforcing long term contracts, not against trade.
related: 6 Years of Noclip.website (2019) https://news.ycombinator.com/item?id=19625068

posted by the creator @Jasper_
No control group?

No comparison across different demographic groups and countries? (for example, different food types being consumed at different times of the day)

No definition of what time and energy intake constitutes "late eating"? (see [1] for an example study that did define "late eating")

[1] https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2006.17
Couldn’t agree more - my kids have been reading the two “big ones” - Cars and Trucks and strings that go, and “What do People Do All Day?” almost every night for a year now. There’s always a delightful new discovery and it’s an endless source of “Why?” questions with interesting answers!