also: References, mostly murine studies but also some human studies: https://www.reviewofoptometry.com/news/article/vitamin-b3-ma...

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9) Kouassi Nzoughet J, Guehlouz K, Leruez S, Gohier P, Bocca C, Muller J, Blanchet O, Bonneau D, Simard G, Milea D, Procaccio V, Lenaers G, Chao de la Barca J, Reynier P. 2019. Nicotinamide deficiency in primary open-angle glaucoma. Invest Ophthalmol Vis Sci 60(7): 2509-2514.

10) Durani Z, Gkotsi D, Chau D, Garway-Heath DF. 2018. The effects of Vitamin B3 on fibroblast mitochondrial function in glaucoma patients. Invest Ophthalmol Vis Sci 59(9): 6036.

11) John SW. 2018. Nutrition metabolism and glaucoma, lessons from mice. Invest Ophthalmol Vis Sci 59(9): 5348.

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13) Williams PA, Harder JM, Foxworth NE, Cochran KE, Philip VM, Porchiatti V, Smithies O, John SWM. 2017. Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science 355(6326): 756-760.

14) Liebmann JM, Cioffi GA. 2017. Nicking glaucoma with nicotinamide? N Engl J Med 376: 2079-2081.

15) Williams PA, Harder JM, John SWM. 2017. Glaucoma as a metabolic optic neuropathy: Making the case for nicotinamide treatment in glaucoma. J Glaucoma 26(12): 1161-1168.

16) Chou TH, Romano GL, Amato R, Porchiatti V. 2020. Nicotinamide-rich diet in DBA/2J mice preserves retinal ganglion cell metabolic function as assessed by PERG adaptation to flicker. Nutrients 12(7): 1910.

17) Hui F, Tang J, Williams PA, McGuinness MG, Hadoux X, Casson RJ, Coote M, Trounce IA, Martin KR, van Wijngaarden P, Crowston JG. 2020. Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial. Clin Exp Ophthalmol 48(7): 903-914.

18) Williams PA, Harder JM, Foxworth NE, Cardozo BH, Cochran KE, John SWM. 2017. Nicotinamide and WLDS act together to prevent neurodegeneration in glaucoma. Front Neurosci 11: 232.

19) Zhang X, Zhang N, Chrenek MA, Girardot PE, Wang J, Sellers JT, Geisert EE, Brenner C, Nickerson JM, Boatright JH, Li Y. 2021. Systemic treatment with nicotinamide riboside is protective in two mouse models of retinal ganglion cell damage. Pharmaceutics 13(6): 893.

20) Osborne NN. 2008. Pathogenesis of ganglion “cell death” in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondria. Prog Brain Res 173: 339-352.

21) Liebmann J. 2019. Nutritional supplements and performance during visual field testing (B3 vitamin). US National Library of Medicine Columbia University 2019: 1.

22) Cimaglia G, Votruba M, Morgan JE, Andre H, Williams PA. 2020. Potential therapeutic benefit of NAD+ supplementation for glaucoma and age-related macular degeneration. Nutrients 12(9): 2871.