skysight-inc/HackerNews huggingface dataset:
I've lived in France and the idea is to make an attempt to speak French. After they have surmised that you sincerely are making an attempt and that you are also butchering their language, they'll do their best to meet you with English if they can.
How do you think those kids acquire money? I guarantee you it's a in a form the government classifies as income.
There's a very easy regulatory solution: Roll the drug approval process back to the way things were done prior to 1962. Back then, safety testing was all that was required. Efficacy testing -- which is difficult, expensive, arguably unethical in itself, and in some cases effectively impossible -- was not required. Drugs cost ~20-50x less to bring to market, and were brought to market faster. Indeed the 40s and 50s are still known as the pharmaceutical industry's "Golden Age." And it wasn't only because of low-hanging fruit.

Pair this paradigm with extensive postmarketing surveillance and periodic reviews for efficacy in a patient population. These could be done at two years, five years, and eight years -- and approval automatically rescinded if safety issues arise or efficacy is close to null.

Give people with fatal diseases a "right to try" drugs that haven't passed safety testing -- and use that data.

Ban drug advertising in public-facing media.

Simple as.
> People forgetting passwords isn't a problem that's solved with other schemes.

Sorry, I should have clarified: that was in reference to users being unable to successfully use the parent's hypothetical 'terribly complex 5FA device-based passphrase scheme'. Passwords don't get any blame here.

> Bank account fees, seriously? I can't remember the last time I've paid any.

OK, fractionally lower interest growth then, or less frequent premium bond wins. In any case, the bank is going to find a way of passing the cost of business to you, so you have an indirect incentive for their business to be cheaper to them.

> If our info can be stolen because someone else chose a weak password, the weak password isn't the problem. It's the system that was badly designed in the first place.

That is correct for some kinds of personal information, like how storing documents on a 'cloud' without client-side encryption is a badly designed system for privacy. However, there are genuinely some occasions where a third-party needs to have access to (not just verification of) your information, but also has a responsibility to keep their copy secure. A hospital might need to see your medical records to do its job, for instance.

> The analogy doesn't hold because you have to first show that alternatives to passwords are better for the users, even those in the category you mention.

I completely agree with you. All I'm saying is that a lot of people will try to replace passwords (because we all have an incentive to improve the situation), even if their replacement fails at being better for users!
They moved over to really dumb word vector stuff, they mention it in the TPUv4 paper and it is pretty surprising but probably monetized better somehow.
Get Well Soon
At minimum, you do not need end to end certification that everything is fit for human consumption. That feels like a potentially huge cost savings vs bioreactor meat.
MyndMap – AI-Powered Productivity for People with ADHD
> thalidomide, a deadly and basically worthless medication,

Thalidomide is what is used to treat erythema nodosum leprosum (ENL) better known as just leprosy.
It appears that he is in New York, which doesn’t have a right to try law on the books.
I knew I wanted my personal site to have some sort of interactive gimmick, seems like the tile grid worked out. Glad you enjoyed it!
Carl Sagan's personal copy of master audio recording NASA Voyager Golden Record
20 Years of SparkFun, 20 Years of Couch Collecting
Is academia actually underfunded, or does is just create a large, underpaid labor class it can motivate with a tenure carrot? I don't get a sense that there's actually that much more research that needs to be done as much as we need a lot of TAs and lecturers.
Interesting it’s GPL licensed. I’ve noticed a lot of these enterprise targeted OSS projects are. Wonder sometimes if this blunts the inertia of their adoption since customizing the software triggers a license violation if it’s not shared
DDG is following Google's path, with removal of the exclusion operator. Nothing like searching for "foo -quux" and finding "quux" in ALL of my search results, on DDG and Google alike.
Looking at my phone and laptop, I have a lot of open source code, some $0 apps, some $50-$100 apps, and a couple of annual subscriptions for roughly $25/yr.

It’s interesting that those price points are sticky, like detents on a slide.
I'm reminded of (I think?) one of Paul Graham's essays on the difficult and rewarding things in life – that if you knew how difficult it would be, you might not have done it? You might not have started.

I don't know... sometimes, there are those things that might be difficult and then not worth it. It strikes me that to be a professor, you have to be a little out of it, maybe even a little psycho.
Windows 95 was years behind the state-of-the-art on the day "Chicago" shipped. The technical choice of the backslash for file system paths, and hiding the real disk contents from the user view, caused years of headaches. The architectural design choices for extensibility ended up as a swiss-cheese architecture for malware. MSFT-chairman literally saw himself as the new savior. glad you see this as important?
Proper synthetics handle sweat much better, so much so that i can barely wear cotton in the summer (live in hot climate). Also i remember throwing away cotton clothes much more often. I wish there was more synthetics beyond sports clothes because they make life just so easier (they also wash and dry easier)
I find the concept of unrecoverable panics extremely weird. Crashing your entire program just because something unexpected happened? Erlang would lime a word with you :)
There is a clear problem, and a good idea here. (i.e. Right to Try) What needs to happen to make this move forward?

I am getting so mentally exhausted learning about a specific problem, and then experiencing the helplessness of not knowing how to push on driving towards some mutually agreeable resolution.

Add in the fact that there is no way to seemingly coordinate the push towards a resolution. Individuals taking action without coordination feels just the same as taking no action at all. Are there any tools to coordinate the push and keep track of progress?
I have a secret obsession with hakank’s constraint programming solutions. One of the things that is difficult with constraint programming is that there are several dozens of solvers out there, and they all have different capabilities and limitations. There have been a bunch of times that I have gotten stuck modeling a problem, find some similar problems with brilliant solutions on hakank’s page, and then realize I should actually be using a different solver or a different language.
I agree, it adds no interesting information, however the fact that you only commented on anti-Russian comment makes it super obvious you are not commenting on it in a good faith.
If the position is such that it doesn't matter who is hired (meaning: there is usually no measurable difference in outcome for people in the role, and all candidates have basic qualifications), then nepotism isn't necessarily wrong, in my view. It creates a level of loyalty that true meritocracy does not, for example. I believe this is the mechanism for a lot of hiring through "networks". What I object to, in these cases, is pretending that the various versions of "basket weaving" are relevant merits, and that there is actual meritocracy.

When the position is such that there are specific requirements; those abilities/skills can be tested with interviews etc, like how it works in most recruitment for professionals.

This is my general perspective. There might be certain cases I'd have a different opinion.
How do you ssh in to your workstation? Via some internet-connected bastion host?
I suppose that depends if you still wanted it to vaguely resemble meat or were fine with a yeast smoothie. Pretty much every beer brewery could likely grow some kind of complete protein microorganism given barley feed stock.
Why should they care about long term health of the company when their stake can change [almost] on a whim?

The whole system seems to exist for short term profits.
The world "simple" is doing so much heavy lifting here, it might as well be written as ______ instead.
My first job out of college I ended up with the absolutely slowest box in the office, which definitely pushed me toward optimizing our app (it wasn't even good on fast machines, but it was tragic on slow), but compile times were murder.

We had a Sparcstation somewhere in the office being used as a mail server and nothing else. I don't recall how but I managed to SMB or NFS mount a directory so that I could edit code on my piddly little desktop but compile it on the Sparc. First time Java really worked as advertised for me.

Saved me loads of time and let me iterate on ideas that I don't think I or my boss would have had the patience for otherwise.

I'm not entirely keen on language servers, but those would be another area where distributed computing could come in handy. I think what might be missing though is a multitenant version. Everyone on my team has a duplicate model of our dependencies loaded into Webstorm and it's a pig.
Hmm, do I set my own password?

From the web site’s POV I certainly do.

But my password manager generates the password and remembers it for me and I only ever see it if the generated one somehow violates the site’s arcane password rules and thus requires a bit of manual manipulation. Which rarely happens.
I read this, and while I felt immense sadness, I will obviously move on with my life soon enough and forget about it. I wondered, if I were ever in the same situation, and someone read what I wrote before dying, they might empathize for a bit, but then they'd move on as well.

I just really wish that there's something beyond death, that there's something out there, and that all the suffering and unfairness and randomness in life is not for nothing. I hope we someday truly figure out what the fuck we are doing here in this universe. And if not that, at least we reach a point in biology where we have the ability to solve a lot of problems of the mind and body and make life better for everyone.
Investors want their return.
The probability of a more painful death is also greater than 0%. So it the probability that something could go wrong and cause publicity which would interfere with the testing or approval of the drug and affect other people's access in the future*. There are always tradeoffs.

*this person takes the drug. Two days later they die of a heart attack. Was it caused by the drug? How many resources should be spent to determine that? Should that death be listed in the potential side effects? What if the news story publishes an article and scares people off from the trial? What if it's later proven that the drug had no effect on the heart attack but the distraction from it delayed 10,000 people's access to the drug?

The world is complicated.
The irony of someone recommending Russian platforms to evade "censorship" is astounding.
'10 year, $50M partnership' - that's a bit low isn't it for any significant amount of cotton/year?
Things don't happen in a vacuum. It’s understandable that people want access to the experimental medicine for themselves or their loved ones when the fear of god has been put into them. When one has nothing to loose, what’s there to loose?

Unfortunately it’s our dignity (or at least others diagnosed with „x remaining months“). As soon as this becomes normalized, the moral impetus will change that those wo didn’t make it, probably weren’t brave enough to try the new stuff.
Misunderstanding of Botox procedure aside ("duck" lips being filler rather than Botox), is this just not a restatement of the toupee fallacy?
People love rats, but they don't want to drink the rats' milk?
In theory, acedemia should be shielded from the pressures industry has to make money on products and whatnot. In reality, the pressured are distinct but similar.
Why would they have left no traces? Dinosaurs lived ~200 M years ago and left enough traces for us to discover them. Wouldn't an industrial civilization 50 mya have left some kind of refined metallic artifacts? Even if _most_ traces are eroded away with time it seems difficult to imagine every trace of a global industrial civilization would disappear.

There also don't appear to have been any spikes in atmospheric carbon dioxide during the relevant period: https://en.wikipedia.org/wiki/Carbon_dioxide_in_Earth%27s_at...

Though maybe you were looking at a data source with better resolution?
Either way it's not as though people seeking death are being mislead as to the odds, are engaging in desperate reasoning that they'll be the lucky ones who get to live a bit longer

This applies just as much to approved treatments as unapproved, for the same reasons, and has the exact same solutions such as having a third party with no vested interests explain to the patient. In fact it has those problems less than approved treatments because the companies are being paid by the insurance company for the approved treatments but not the experimental ones.
Balls the pet fruit bat (1978) [video]
I’m fine with that as long as insurance does not pay for any drugs without efficacy testing. Also no advertising of any sort.
You have identified a key problem in modern capitalism.

None of the answers that actually solve the problem in good ways can be found in "more capitalism".

Kids will attend school if and only if their families send them. The expected economic value this week needs to be higher than the value of putting the kids to work. Saying that educated kids will have a higher economic value in the future is useless in the short term.

Long term, the countries that haven't gone through the demographic transition need to be pulled through it.
Yes. The basic reason is lazy evaluation and answering the primary question most people care about when using an actual real number in a computation.

The lazy evaluation is that defining the real number is about having a way of answering the question when presented with the rational interval, but one does not actually need to have the answers until asked.

From this perspective, a program that computes Yes or No when given a rational interval via the rule "a<b Yes iff a^2< 2 < b^2" can be said to be the square root of 2. For the usual presentations of the other definitions, they cannot be embodied in a computer. One cannot literally have all the infinite elements of a Cauchy sequence, or the infinite sequence of digits in a decimal representation, or the uncountably many elements of a Dedekind cut, represented in a computer memory. One can have a function in memory.

The other definitions can also be presented, in various ways, as functions as well, but I think, fundamentally, what we want in practice from a real number is an interval of small enough size to be of use in whatever we are doing with the real number. That is what the oracles facilitate.
Carbon is definitely not the new oil. My hope is that carbon becomes the feedstock of the future (with a long way to go).

Exxon is an easy target in this but there are many other companies and industries that are working towards carbon capture.

I'm working with ethanol producers, co2 utilization companies, direct air capture, and other capture technology companies to move the carbon management industry forward. Exxon will be a player but not THE player in carbon management.

The article fails to mention that Denbury has several Class VI well permits (these are the wells where CO2 is injected) in areas near Denbury pipelines. Everyone will talk about the Gulf Coast as the strategic reason but Denbury's pipeline in Wyoming will be key to advancing the industry since Wyoming and North Dakota have authority over the Class VI wells today. I've heard estimates of 40 million tons of CO2 storage capacity in one of the Wyoming projects (that's just one of several projects).

Disclosure: I monitor carbon management at https://decarbonfuse.com by tracking the ccus, dac, and beccs projects in North America.
> Unfortunately this means that there's probably not much chance for a rich field of xenoarchaeology to exist since it's not even possible to do this on our own planet.

I think you've reached this statement too eagerly but would be interested to discuss this point. Do you mean that the materials they used would have disintegrated and their (presumably carbon-based lifeform) bodies wouldn't have left any fossils?

My main thoughts on this come from reading Vernor Vinge's [1] excellent Marooned in Realtime which discusses some of the condundrums resulting from transferring information over massive periods of time. I think part of it talks about subduction zones where everything is eventually riven back into the Earth's mantle, essentially lost to any kind of current archaelogical techniques.

[1] https://en.wikipedia.org/wiki/Marooned_in_Realtime
Yes, but the difference is going to not be as much as you are loosing on the house.
Felix Krause did: https://howisfelix.today/?

HN search will also pull up several prior discussions.
It used to be regarded as a miracle drug that could be used over the counter in many circumstances, and as they looked into it they discovered it just couldn't be used safely.

That they've narrowed it down to some use case is more of a testament to the thoroughness of the investigation, I'm sure there are many chemicals that could treat leprosy this just happens to be the one we understand how to manufacture and when it is safe to use.

I'm sure it's very meaningful for the people who do take it, but that is what I meant by "basically worthless."
I think AI finally is at point where it is. It’s peak hype right now but there is definitely a difference between knowledge workers that use it and one’s that don’t. It’s only going to grow wider in the coming years.
The FDA can approve a new drug in under a year as we saw with covid vaccines. Every time an effective drug is made and they don't people die waiting.
Cotton is probably bad for biking anyway as it’s a sponge so your sweat will just leave you with a drenched shirt.

But I am trying to avoid plastic clothes because of their environmental impact, and possible leachate ending up in (or through) my skin.

Wool, and cotton/wool blends work for me even in the summer. Amazingly a return to my childhood in this regard! But they are a little more work to look after than the plastics.
The consequences to their actions are that when a doctor prescribes me a medication or when I purchase one off the shelf, I have incredibly high confidence that if I follow the dosage instructions it is safe - safe now, safe in 15 years, not worth further thought on my part. That hasn't been true in most places for most of human history.

The consequences to their actions are that millions of people are saved from the consequences of consuming seemingly promising drugs such as Thalidomide: https://en.wikipedia.org/wiki/Thalidomide

I could sleep just fine knowing that some people looking only at a tiny local example while ignoring the big picture considered me the villain
Oh quite! I myself am outside of the networks of industries I want to be in. There is an altruistic side to getting the job you really want - you'll be more motivated and probably better able to do well in it. Industries that operate exclusively with networking lose out on most of that altruism.
For one thing, I now have to be logged in on my mail on the device I am using, and that means if the device is unsafe, I am exposing far more of a risk that way.

It also forces me to look at my email inbox, which can be a pretty annoying thing if I am trying to relax and now see some email with bad news - requireing me to break the flow again.

Most important however: it is simply wrong and not needed. The flow has been settled.
No. Those plugins call functions from AGPL's codebase and they are designed only to be combined with AGPL's work into a larger work, so they are derivative works.

But there is a chance that CSS and svg icons are not required to be GPL.

See WordPress clarification on themes' licensing:
https://wordpress.org/news/2009/07/themes-are-gpl-too/
My Dad was dying of IPF and I was always on the hunt for anything that may help. Of course there are countless quack "cures" but I came across a study that said metformin may help. Metformin is what people with type 2 diabetes use to help to control blood lipids among other things. My Mom actually takes metformin since she has type 2 diabetes. My Dad's doctor wouldn't even discuss it and dismissed it outright.

Dad died in 2021 and I find it difficult to think metformin may have helped him live a more comfortable life. I know it's not a cure but the research seems to indicate a significant improvement for anyone with IPF taking metformin along with anti-fibrotic medications which Dad did take. We should have just used Mom's metformin really Dad had nothing to lose but it's hard to see that at the time.
I really have no insight as to how to get the horse back into the barn, and suggest looking for professional help for yoyr kids.

All I can tell you is that my kids do not ask for social media or even screens that much because I plan outings for them that are more interesting and exciting - and that isn't about spending a ton of money or going very far, just being creative about how to frame what we're doing. For example, when planning to go to the local pool, I make up a story about how at their age I was able to run across the pool in X seconds, and that if they can break my record 5 times, I'll take them out to a restaurant for dinner the next day. Then when we are there, I'll also break out some plastic water toys that I didn't tell them about.

I just make family time more fun in terms of anticipation and surprises than being online.
That's true, though I'll note that treatment options seem to have broadened a bit [0]. Thalidomide is effective, but suffers from cost and limited availability (in addition to the teratogenic effects).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413435/
The key is that the approved treatments are proven to have the requisite efficacy, the risks that come with that are an acceptable tradeoff. The unapproved, often largely untested world of early breakthroughs doesn't have that guarantee of potential efficacy, it often JUST has risks.
There are many divergent if not contradictory regulatory findings levels and limits between the US Canada and Europe.
eg. Tolerable total cholesterol levels US:200 Euro: 240 (last I checked, these move around quite a bit. In the 70s the US banned Cyclamates as an artificial sweetener, but approved Sacharine while Canada approved Cyclamates and banned Sacharin.
For Glaucoma treatment Europe is "Laser first, drugs second" while the US is Drugs first, laser surgery second.
etc etc.
How often do you need to buy a new one?
"Best Practices (BP) papers, up to 10 pages. Suitable papers are those that provide an integration and clarification of ideas on an established, major research area, support or challenge long-held beliefs in such an area with compelling evidence, or present a convincing, comprehensive new taxonomy of some aspect of secure development. Such a paper would be marked with the prefix 'BP:' in the title, and would need to provide new insights, although it could draw upon prior work." [https://secdev.ieee.org/2018/papers/#best-practices]
I don't believe that Twitter has to limit requests to avoid bots.

They would just have to limit requests by IP and thats it. Say 10 tweets per IP per day. For requests which do not come from logged in users.

I can't see how scrapers would be able to come up with enough IPs to make a dent in Twitters costs.
VSc over ssh? Jetbrains Gateway? I think both work decently.