skysight-inc/HackerNews huggingface dataset:
(2020) Will COVID-19 be evidence-based medicine’s nemesis?

https://journals.plos.org/plosmedicine/article?id=10.1371/jo...

"It is surely time to turn to a more fit-for-purpose scientific paradigm. Complex adaptive systems theory proposes that precise quantification of particular cause-effect relationships is both impossible (because such relationships are not constant and cannot be meaningfully isolated) and unnecessary (because what matters is what emerges in a particular real-world situation). This paradigm proposes that where multiple factors are interacting in dynamic and unpredictable ways, naturalistic methods and rapid-cycle evaluation are the preferred study design. The 20th-century logic of evidence-based medicine, in which scientists pursued the goals of certainty, predictability and linear causality, remains useful in some circumstances (for example, the drug and vaccine trials referred to above). But at a population and system level, we need to embrace 21st-century epistemology and methods to study how best to cope with uncertainty, unpredictability and non-linear causality [16].

In a complex system, the question driving scientific inquiry is not “what is the effect size and is it statistically significant once other variables have been controlled for?” but “does this intervention contribute, along with other factors, to a desirable outcome?”. Multiple interventions might each contribute to an overall beneficial effect through heterogeneous effects on disparate causal pathways, even though none would have a statistically significant impact on any predefined variable [11]. To illuminate such influences, we need to apply research designs that foreground dynamic interactions and emergence. These include in-depth, mixed-method case studies (primary research) and narrative reviews (secondary research) that tease out interconnections and highlight generative causality across the system [16, 17]."

table1: https://journals.plos.org/plosmedicine/article?id=10.1371/jo...
Yeah, it's too hard to just `useradd -m name` a new user, maybe set default acl once via setfacl -m d:u:main-user:rwx /home/name for easier file sharing with the main desktop user account, and `sudo su - name` to it, and run whatever less trusted apps need to run under that user account from then on, mostly isolated from the rest of the [file]system.

Distros clearly don't allow this and none has this feature or these commands preinstalled by default, nor they are built to be multi-user OSes. :D
Is being scared of gays a fact or a feeling?
The US has second, third, and fourth tier leagues already, though those are all part of USL rather than MLS. MLS has a lot more money than USL and isn't interested in promotion/relegation concepts because it is built like MLB/NBA and likes the gatekeeping aspects of those because that influences investment money and helps keep MLS comparatively rich. But USL thinks promotion/relegation could work in the US, they just don't think it can work that well if they don't also control the top tier league. From my understanding USL has quietly been hoping that play in the USL Championship league (their top tier and comparatively in the US market the "second tier" overall) could get competitive and interesting enough to usurp the MLS and put USL in a place to have the top-tier and move to a "proper" European-style relegation/promotion system.
Can I bother you for a RED invite? My email is on my profile, or I can email you (your email is on your profile, but I don't want to bother you too much).

I had a what.cd (and waffles.fm) account in very good standing, but I never got on to RED, because I never really did the interview on account of having to idle on IRC for a long time.
What if members of a particular race are more likely...

I would advise caution with that phrase. Having grown up in a, shall we say, less enlightened area of the U. S., that phrase was the prefix to many a racist statement that I heard in my younger years. I'll assume, of course, that your intent is to just have a pleasant online conversation on the topic at hand.
There's some irony here: short expiry has some clear practical benefits for at least some of the goals of the WebPKI, and that works because the WebPKI has stakeholders that will push things like "if you issue one more SHA1 certificate we will distrust your CA". Certificate expiration failures are common, but not that common, because "needs a certificate" isn't the default for every host.

Key expiry is a much bigger problem for DNSSEC, since once you sign, every hostname in your whole zone depends on no RR in your DNS configuration expiring. But there are no stakeholders extracting any value from those expirations: nobody can say "if you sign one more record with RSA-1024 we will break your whole TLD".

Further, unlike with the WebPKI, where verification is conceptually offline --- you have a trust anchor and a signature chain and the verification is all done locally --- DNSSEC resolution is online: you have a TTL issue with revocation, but not a "this bogus signature will be valid for an entire year because there is no effective revocation system".

So, arguably, the RRSIG expiration field is another fundamental flaw with DNSSEC.
Location: Remote
Skills: UI/UX design for B2B SaaS startups
CV/Portfolio: https://www.fairpixels.pro

-

If you’re building a b2b SaaS product, check out previous work and process
Best comment on the thread.
Here's the Hunting of the Hare (starts on the page marked 113 and it's in Middle English, but there's a glossary after): https://www.researchgate.net/publication/236869902_'The_Hunt...
Need to have a $/watt-hr metric to know if this will be viable. This reminds me of the Windbelt generator from several years ago. It was a brilliant design to extract power from low speed wind, but did not find economic value with existing cheaper forms of generation.
There was a different article reporting on this that mentioned they would have to stack many layers into a block "about the size of a refrigerator" to make kilowatt. I will try to find it.
‘Mental Health’ Is a Political Mirage
> in the one-month period covered by this study, the city's police officers did 588 stops of Black drivers and only 262 stops of white drivers.
Yep even old Reddit does not replace RIF for me. The only reason I even browse Reddit anymore (rarely compared to before) is because of how much I prefer RIF to any other "social media" app... That's why I never use it on desktop, because I actually have to interact with reddit's UI (which sucked even on the old version).

I wonder if there could be a way for each user to add his own API key? If that's even possible at all to do with the new changes.
If you put up your home or property as collateral, you can still own the property will getting lower rates. Similar thing with the Dai loans I am describing there.
Absolutely, without exception.
Some better information in this article: https://www.heraldscotland.com/news/homenews/23557334.librar...

The manuscript itself seems to be available here: https://digital.nls.uk/early-manuscripts/browse/archive/1336...

I freely admit I cannot read it :)
Barracuda Email Security Gateway Appliance (ESG) Vulnerability CVE-2023-2868
Email Admins will want to take note. Network Admins should investigate the IOC. Security Admins will do what Security Admins do...

"While the investigation is still on-going, Barracuda has concluded the following:

The vulnerability existed in a module which initially screens the attachments of incoming emails. No other Barracuda products, including our SaaS email security services, were subject to the vulnerability identified.
Earliest identified evidence of exploitation of CVE-2023-2868 is currently October 2022.
Barracuda identified that CVE-2023-2868 was utilized to obtain unauthorized access to a subset of ESG appliances.
Malware was identified on a subset of appliances allowing for persistent backdoor access.
Evidence of data exfiltration was identified on a subset of impacted appliances..

Users whose appliances we believe were impacted have been notified via the ESG user interface of actions to take. Barracuda has also reached out to these specific customers. Additional customers may be identified in the course of the investigation.

CVE-2023-2868"
Location: Remote (US)
Remote: true
Willing to relocate: false
Technologies: C#, ASP.NET, SQL, MongoDB, Kafka, RabbitMQ, Azure, AWS, Terraform, Docker
Resume: email me
Email: throwaway37583463@gmail.com

I've been working professionally as a developer for 7 years, and I have experience building and maintaining APIs that serve 300k+ requests per minute to our millions of customers. I'm seeking a senior backend engineering position.
I consult for a lot of companies and I never heard of or seen a database that wasn't horizontally scaled.

It's not for scalability reasons it's for high-availability.

Which as cloud adoption has increased and server uptime has decreased is even more important.
Was wondering when this might come out. Ghost doing it and having such success seemed like something that would spread to competitors.
Observability for Your Cloud Dependencies with Jeff Martens of Metrist
No better example of this than Racket.

Function application itself is an overridable function. (f 1 2 3) compiles to something like (#%app f 1 2 3). And you can hook into that.

Runtime type checking, stack traces, debuggers..
I guess this is sort of to wind turbines as wave power is to hydro? (in that they're taking advantage of a sort of smaller effect)
Thanks Ken! We’re just adding support to MD5 and SHA256 hash personally identifiable information but that’s only one way… the next step is definitely tokenization which allows obfuscation and reversal to those with the right permissions.. this would allow you to abide by the growing number of regional privacy restrictions.
I bought a thinkpad keyboard with the red joystick thing when I hurt my shoulder - it was only supposed to be temporary but I find myself rarely using my mouse. I’m not a great fan of the keys (especially compared to Mac keyboard).
What you say is indeed true, but the part of the post "Existing Visa Transfers Welcome" might attract some groups who don't know the way things work and who may be more desperate (and not willing to reject) such terms.

In theory, any extra replies to a job post which are not beneficial would end up as collapsed noise anyway, right?
There have been a bunch of similar submissions recently, all with 0 comments save for this one:

https://news.ycombinator.com/item?id=36139729

AI camera with no lens (theprompt.io)
1 day ago | 84 comments
Wow. Check out no: 2. U.S. willingness to capitulate in preference to engage in atomic war.

I guess they had no clue how the American Psyche works. Japan sinks 6 vessels, U.S. drops the sun on Japan. Not once, but twice, for good measure. You'd think Russia would watch and learn. They haven't learned anything, even today.
It also gives candidates a good story even if they don't get hired.
The risk of psychedelic drugs is more comparable to motorsports, the more involved action sports, heavy equipment operation, etc. and your average person would be very wary of participating in these even though there are plenty of risk mitigations for these activities.

I'm not saying you shouldn't do drugs. I'm saying that many of them require way more respect than most people realize they need to give them, and trying to downplay that is not good. I can tell you from personal experience that it's easy to get yourself and people you care about in dangerous places.
At Hipcamp, we're hiring a remote Platform Engineer. Hipcamp's mission is to get more people outside. In addition to the usual benefits, at Hipcamp you also get $1,000/year in Hipcash to camp with us in the U.S., Canada, Australia, and the UK. It's basically a dream job for outdoorsy techies. Apply here! https://jobs.lever.co/hipcamp/b0eb200c-e92a-4f8b-8c40-a516e2...
As a rule of thumb, I find it's usually safe to dismiss criticism of HIPAA from anyone who misspells it as HIPPA. Not knowing that it's an acronym for Health Insurance Portability and Accountability Act (emphasis on portability there, as you pointed out!) tends to be a sign that you don't know what the hell HIPAA is or is for.

"HIPPA," on the other hand, is an ever-convenient boogeyman you can invoke in all kinds of situations.
If a reliable primary key exists, it can easily be misused for many purposes: On the more benign side replace the Android Advertisement ID. On the malign side registering political opinions of citizens.

I don't want to live in such society. Yes, bad things can and have be done before. But making them simpler, cheaper, and more scalable needs to be avoided.
Wait 'til they find out that the kind of stuff they build is way easier to apply to attack than to defense...
Isn't this kind of research illegal? Because the results usually are. (I say as someone who used to own marbled crayfish[1])

[1] https://en.m.wikipedia.org/wiki/Marbled_crayfish
SQLite does support auto-incrementing: https://www.sqlite.org/autoinc.html. Is your gripe with the lack of "GENERATED BY DEFAULT AS IDENTITY" syntax specifically?
Great news! Congratulations for open sourcing it! Hope the best for the future.

Edit: I'm a happy user ;-)
Teletext – When Less, Was More
Looks like a great idea. Good luck!
Occasionally I'll click on a site, say a brewery, that asks me to put in my birthday, usually though a slider wheel or form. 90% of the time I just go to a different site. If I'm just browsing around I don't care that badly. Same with modal popups.

I suppose if I was a kid who wanted to get to a site, I'd be more likely to make up an age. My point is that asking stupid questions to anonymous users probably turns away more legit users than kids.
What an absolute joke that you can upload files on demand to someones phone as long as you have a number or an email
Anyone else find thunder foot to be intolerably smug and self righteous? That combined with the fact he never addresses some of his considerable factual errors means I'll pass.

It's fine (and good) to be a skeptic, but you should also understand your own knowledge gaps and be curious. Thunder foot fails here.
That's exactly my experience.

In areas where I'm an expert, I find myself correcting ChatGPT constantly. But for a language I want to learn, it's been really helpful to get me started on a simple algorithm or debug an error message.
discussed quite a bit from every news source possible; using the search function will go a long way when submitting "news" stories:

https://news.ycombinator.com/item?id=36147252

https://news.ycombinator.com/item?id=36143308
At a personal level, why would one care? Their medical issue went away!
Location: Clearwater, FL

Remote: Only Remote or hybrid depends on company.

Willing to relocate: Depends on the company and location.

Technologies: Javascript/React/React Native/Typescript/NodeJS/Python/HTML/CSS/SQL/NOSQL/Git (w/branching strategies)

Résumé/CV: available upon request (please email)

Email: autonomousmachine@gmail.com

Senior Frontend engineer (a little backend and API design sprinkled in throughout the years) 17 years professional experience. Learning new things everyday
A group I'm working with has found that using the OpenAI models through Azure can result in faster response times, but I don't have tangible data to share right now.
what metric are you using if not popularity? the raw # of games put out on the market?

I can remember the online game thing starting way back when I was still playing. Quake had an ethernet option, and I remember something called "Unreal Tournament" spreading like wildfire around dorms when I was in school. My first though was "it's really fun shooting at real kids instead of barrels!" immediately followed by "this is going to be really hard to crack!" I figured every developer would move online by now just to kill cracking.
There was a great book about Evidence Based Medicine, from a woman out of Oxford, I read a long while ago. Can't for the life of me remember the name, but Oxford does have a center for "Evidence Based Medicine," and the whole idea has been slowly coming back into fashion.

Instead, all I can recommend is a collection of essays -- loosely -- related to the subject: Where's the Evidence?, Silverman

---

On another note, someone who's gone down the pharmaceutical research rabbit hole and concluded a lot of it is "bunkum" (e.g. statins, anti-depressants, and so on), would do well to look into surgery next -- especially that of surgical implants.

Some of worth looking into: joint replacements, joint and spinal fusions, angioplasties.

Of note: spinal fusions were not brought about on any scientific or experimental bases, but on hunches from surgeons (damnable bunch). Many do result in a reduction in pain, but it does bring to question how much of it is simply "placebo." There were a few experiments in this realm of doing double blind (or single blind, it escapes me right now) studies on back surgeries, that showed evidence the placebo effect was involved. The simple act of being put under anaesthesia, and convinced one had gotten "treatment," resulted in reductions in pain for those who came in for spinal surgery.

I do wish more research would be done into the placebo effect, and doctors would stop faffing about in self-righteousness (though having an air of expertise and authority does impact the placebo effect positively). And I don't mean in a "the placebo effect exists and is usable as a treatment" way, but in a "the placebo effect exists, and here is how it works in the body." That would be very interesting. Long ago I read a few papers on the placebo effect in regulating blood pressure via regulation of a certain chemical (it could have been a hormone like renin, but I can't recall). At the time, I thought the autonomic nervous system would be a good avenue to research to better figure this out (it would be a convenient explanation for how the placebo effect works: activating the nerves in the kidneys via the cross-talk from the central nervous system to excrete certain hormones). If it can affect the kidneys, what other bodily systems can it impact? The possibilities are not endless, but rather exciting.

I believe the "placebo effect" is the reason chiropractors are so popular, in spite of there being no real physical evidence as to why their treatments help people.
If you're going to learn assembly for the first time I would say start with arm-64 assembly first, the architecture is much more refined and the assembler much more pleasurable to code with less foot guns and complication unless you are doing only the most basic of programs.
You can also mutate a list that is passed in and suddenly you cannot do substitution to reason about your program.
My guess is sort of. If they really wanted it to be ranked they might have the number in the ID repeated at the start of each of them.
Hubble’s great discovery concealed a tension that still haunts cosmology
I just want the shift-ctrl-c to be in every browser. Probably my favorite feature from Arc.
https://status.barracuda.com/incidents/34kx82j5n4q9

And

https://status.barracuda.com/
It shows the power of a well placed PR person with good contacts. Powerful enough that the paper would delay the announcement of the hiring of the guy who wrote the Wall Street story's that took down Theranos.

Elizabeth Holmes should have had zero possibility of getting a puff piece written about her in the New York Times, yet she did.
Found it.

"Yao estimated that roughly 1 billion Air-gens, stacked to be roughly the size of a refrigerator, could produce a kilowatt and partly power a home in ideal conditions. The team hopes to lower both the number of devices needed and the space they take up by making the tool more efficient. Doing that could be a challenge."

https://www.washingtonpost.com/science/2023/05/26/harvest-en...
Democracy doesn't imply or require any of those things. A majority can democratically vote to suspend every single one.

You can have a democracy with 51% ruling and 49% in chattel slavery and poverty (but having a right to vote

I would agree that socialism isn't compatible with private property and civil rights as we commonly understand them today (in the US).
I know of two companies that provide this. My experience is with software written for government entities by a third party. Every time we cut a new release, we would have to go through an escrow process to provide the services with a VM image that would allow our clients to build from source our entire software stack along with the ability to host the software either in house or in the cloud. It was a very expensive and time consuming processes and my ex-employer charged a fortune to any clients that wanted it.

https://nationalsoftwareescrow.com/what-is-software-escrow/

https://softwareresilience.nccgroup.com/software-escrow-serv...
That they were horrible people is irrelevant to the question: were they right about the "Communist goals"?
That so many of the items in this list came to pass, either completely or in part, is prima facie evidence for 1) the existence of long term social planning in the West, or 2) the ability of the Birchers to correctly extrapolate from current trends to future events.
If you like Reggie Workman, I can't recommend his collaboration with Terumasa Hino highly enough: https://www.discogs.com/release/5515016-Terumasa-Hino-Meets-....
ASRock Showcases Two New Intel Z790 Motherboards with Wi-Fi 7 at Computex 2023
those keyboards are great for servers or headless workstations. i have one on my thinkstation for the occasional moments where i need non-networked access. i have the usb version but they also make a wireless one.
Person claims to be a 'Marketing PhD candidate', I'm not sure they have grounds to be complaining about any kind of net utility.
Mondrian rules! In my youth I tiled the bathroom in my house in a Mondrian pattern. Mostly white, lowering the cost since white tiles were much cheaper than red yellow and blue.
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Had to look it up but that is the zip code for Lafayette. it was probably the best out of several bad choices.

A direct gmail domain is understandable for a small city government but it does look unprofessional. I liked how governments were one of the few organizations that took advantage of the hierarchical nature of dns, you would get things like dmv.ca.gov and courts.sf.ca.gov Unfortunately that is going away as well. everybody has to have a second level domain and now you have stupid things like lovelafayette.org instead of lafayette.ca.gov
Even solvency, apparently.
Hi - there are some remote positions available on https://HardwareTeams.com
This isn't a problem with Satoshi's original protocol design. You should use BSV instead.
Binaries groups devolved into UUEncode spam at the gigabyte level, and private servers sprang up to provide access to curated piracy, so there’s that as well.
You left out a variable: black people make up what percentage of that population of that city? If it's, I dunno, the approximately 15% that I would guess it to be, then that's a significantly large number of stops in comparison to white folk.
You're still proving rcconf's bigger point - don't sell tools to developers, because we suck to sell to. This leaves us with shitty free tools, or really expensive ones that tie us to our employers. Want to leave your job? I mean, sure, you can, but on top of needing to find a new job, you'll need to learn a completely different development environment. Which is just life, I suppose.