skysight-inc/HackerNews huggingface dataset:
https://www.supermicro.com/en/products/system/4U/6048/SSG-60... - 4U 72 drives
Easy wealth? I am not sure how to respond to this.
In the US there are many ideas about how things work in Sweden without closely considering facts. This is often politically motivated regardless of political affiliation.
>Some people don’t want to work.

Good. It's preferable that people who don't want to work stay home and do other things, rather than coming into the office and not working.
If this change makes moderation more difficult, it negatively impacts all users of the site.
I've actually seen this usage pattern in the practical usage of logic programming libraries. Common Lisp's Screamer [1], for instance, or Clojure's less-mature core.logic [2].

Though to be fair, both of these libraries are in Lisp languages, which inherently support the design pattern of slipping into/out-of DSLs.

[1] http://nikodemus.github.io/screamer/
[2] https://github.com/clojure/core.logic
Opera on mobile does offer some sort of an adblocker built in.

However as it is a commercial company and free product, not sure what are the tradeoffs for using Opera.
Only in America (and third world countries).
The current variants seem to be much less severe.

Depending on age and health, it really makes it difficult to say if getting vaxxed was the “smart” move when weighing the risk of contraction vs the unknowns of any potential side effects.
Database engines are getting features like SELECT FOR UPDATE SKIP LOCKED, so what were once serious blockers on this idea may no longer be as much of a problem.
> I could be wrong. Absolutely. I am always open to more information.

You're still a bit too cynical but there are some nuggets of truth in what you're saying.

With regards to mutation testing: I'm not sure where this Hopkins guy is getting his data from but mutation testing for lung cancer is already standard of care, it's been part of the NCCN guidelines for > 5 years at least.

EGFR is not the only driver mutation and osimertinib is not the only drug that can be used, even for EGFR.

Molecular marker and genetic testing of cancer is unequivocally to the benefit of patients and is not a BigPharma scam, it also has little to do with this specific drug other than that this is one of many gene-directed cancer therapies.

> 2) it will be a net negative for patients^
> ^ Patients would be better off with more money and using an alternative treatment strategy. This drug is priced at $12,750 per month, according to Wikipedia.

Be careful with generalizations like this. This drug is very signficant, you just have to select patients appropriately.

There is no doubt osimertinib works well, if you have unresectable/non-curable lung cancer it can potentially buy the patient an extra couple of years (median ~8 months) over previous generation TKIs and even longer versus conventional chemo. These patients used to just die within a few months 5-10 years ago.

This article, and the trial it talks about, is about adjuvant therapy (i.e. after the surgery) in patients with locally-advanced but curative intent disease that at baseline have pretty good good survival so in this specific use-case your criticism of cost-effectiveness is a reasonable one.

Consider a 45 year old with an EGFR mutation and stage IV lung cancer (unfortunately common these days), an extra 8 months-3 years is immensely significant for them and their families and this is a miracle drug.

On the other side of the spectrum, for a 75 y/o with stage II cancer who underwent curative-intent treatment (i.e. this study population), the argument is much weaker given the costs vs low absolute risk reduction over a long time period. I broke down the financials in another comment.

You're probably right that the numbers won't add up in this trial for this specific patient population, the article + PR releases so far do smell a bit like AstraZeneca buffing somewhat underwhelming results (expectation was that overall survival would look better than 10%) to sell more of an expensive drug, but you're overgeneralizing and it is a very good treatment option in well selected patients. It will also be a great adjuvant treatment option whenever this becomes cheaper like 1st-gen TKIs are now.
HN is functionally like a single topic forum, which makes it a little easier to have rules about what is generally allowable content. Many single topic forums still exist, though in recent years have had to take a back seat to Reddit et al. Maybe if Reddit goes completely to pot, people will look them up again.
Safe way to store hydrogen using iron pellets
I have run a locomotive in a tunnel on concrete slab. Low temperature range for the air. The air had high humidity due to persistent water leakage. We didn't do much track maintenance and simply went slowly on bad sections of rail.
Bullshit. For most of those 60000 years speech didn't work "fine" at all.

The majority of people that lived in those times where ruled by empires that had nothing resembling free speech or the rule of the law.

You wouldn't even think of bad things against the King or Church in Europe before the 19th century. Same goes to Middle Eastern Empires, Chinese dynasties, the Japanese emperors or Shoguns, etc. Even less than think you'd say anything to offend established powers. Yes, even the Roman Republic was not democratic or free for all.

And your "inbuilt biases" are just a justification for sexism, racism and other forms of discrimination created by specific historic circumstances. There is no "inbuilt" basis for discrimination.
- fraudulent “commingling” is above board with just a little paperwork

- OpenAI is for-profit but this guy’s crusade is based on it still being non-profit with a misunderstanding of fiduciary duty to its beneficiaries

fascinating, is this an example of America’s mental health crisis?
Such as?
And more importantly, is there the slightest evidence that putting such monitoring in place actually helps increase output?
I'm an Apollo user and I'll be dramatically reducing my use of Reddit if and when the third party apps are killed. The official Reddit app is nearly unusable, with a remarkably poor UI and too many ads. It also doesn't offer the tools for subreddit moderators that third party apps do.

The hope is that, despite being a small percentage of total users, third party app users represent a large volume moderators and high value contributors. If that's the case, this change will hurt Reddit enough to potentially roll it back.

What will probably happen is Reddit will tell us all to pound sand and we'll find alternatives.
Or just makes a poor connection to begin with due to out-of-spec cables or connector wear/damage, which is likely considering the much tighter tolerance than old-school, reliable, battle-tested connectors such as barrel jacks.
It's hard to train a chat AI directly off people's use of it. Some users will just dump spam in there, trying to trick it, lying to it, etc.

Instead, I believe they use logs of user chats to detect when the user was dissatisfied with the AI's response (for example by detecting closing the window). They'll then pay a human to review these conversations, and if a human can write a better response, then that will go into the next round of training.
The structure is well known, and is neither what is being argued in the lawsuit, or asked from ChatGPT. I am not commenting on the merits of it, that is for the courts.

So what is your take? Are they on it for Profit or to save Humanity? Should we nominate already Sam Altman and Reid Hoffman for the Nobel Peace this year?
Legally it's governed by the terms of use which for most sites say something along the effect of you retain copyright ownership but transfer a non-revocable unlimited license to the platform.

Sometimes other legislation, like EU right to to be forgotten, GDPR, etc. overrides that and they have to take it down, but otherwise they could pretty much do whatever.
I have no clue if Americans write better software, but they sure are willing to pay better for getting software written.
> It incentivizes the right people

Wrong, at least in my experience. Professors with published books wanted us to buy those books for their course. They would just pass the cost (from which they profit) back to the student if they were bundling, with no alternative to the student.
Crun: Fast and lightweight OCI runtime and C library for running containers
The Old Computer Challenge V3
This is indeed a nice idea, unfortunately the university (mine) gets kick backs from the book store. At the beginning of every semester every faculty gets an email asking us to 'encourage' students to buy their materials at the book store. Every semester I do what I always do and tell the students that the ($250!) book will not be used in class (although mine is just one in a sequence and the book is chosen by the whole department for the whole sequence) and give a half a dozen references to (excellent) free online books. Even then some students for whom the class is the terminal one in a sequence buy their books. Must be human nature at play. On a different note, as a flight instructor, when a future student asks me what to bring to the intro flight, I usually say 'lunch', since I provide everything else, including headsets. Yet half of them bring $500 worth of useless gadgets and expensive books (not, strangely enough, headsets) to 'be prepared'.
> They all literally share the same DNA, they can't be that different.

They share the same DNA in the sense that every cell in that body does. But the different types of cancers have different mutations per cell type and the increasingly precise identification of those is the basis of the recent new treatment options. Histological classifications become less and less relevant, instead mutations and subtypes of mutations give directions for treatment paths. So I think that statement is a bit confusing.
I understand your views and concerns. It's true that change, especially rapid ones, can have unexpected consequences. Traditional values and methods can often provide stability and a sense of continuity, which are important. However, I'd like to provide some points for your consideration.

1. *The Green Movement and Nuclear Power:* While it's true that some green advocates have opposed nuclear power, it's not accurate to say the entire green movement is against it. Many environmentalists see nuclear as a necessary part of the mix to reduce greenhouse gas emissions, especially in the short term, while renewable energy capacity is being built up.

2. *Urgency of Climate Change:* Climate change is indeed a pressing issue, according to a consensus of climate scientists. Rising temperatures, increased frequency of extreme weather events, loss of biodiversity, melting polar ice and rising sea levels are all current realities. While the growth of renewables is encouraging, current projections suggest we are not transitioning quickly enough to avoid severe impacts.

3. *Understanding Conservative Voices:* I agree with you that understanding and appreciating diverse perspectives is essential for a functioning democracy. It's not about left or right, but about finding common ground and working collectively for the common good. Climate change is a shared problem that requires cooperation across the political spectrum.

4. *Change vs. Tradition:* It's not about destroying traditions but evolving them to meet current and future challenges. Traditions can provide valuable lessons and a solid foundation upon which to build. Yet, we should also be open to new ideas and solutions that align with the scientific understanding of climate change and its potential impacts.

I believe that it's essential for us to look past our preconceptions and work together to address climate change, an issue that affects us all, regardless of political or ideological leanings.
Everything is possible. We're discussing what's likely and not likely. I don't buy the hallucination theory. BTW, technically it "hallucinates" everything, because it has no connection to the outside world, only memories to base its answer on. But if the hallucinations are correct, then being less correct is still a problem. If you can show it's more correct in other ways, be my guest.
Why this is even controversial is a mystery to me. Anyone who has had young kids in daycare knows this. If the study had been about the common cold instead of Covid, I doubt so many people would be triggered.
That's how I caught it the second time.

Daughter came home from school with a note telling us that a kid at the school had spent 3 days in class with a positive test, but the parents sent her anyway because they had nobody to watch her and because kids didn't "have bad reactions."

A few days later, I noticed that I lost all sense of smell and I've had long covid ever since. I miss being able to enjoy citrus and peppers and days where I'm not completely exhausted by 5pm.
It is merely a tool, guided by the same principle Aaron Swartz implanted into reddit. Freedom of choice, freedom of expression, as long as the laws in the country hosting the servers are upheld. Communities can form and moderate the content as they please, but alternative communities can also form with perhaps less moderation. It is up to the users to make it what they want, not funded by advertizing, but rather with potential donations. It doesn’t have to be huge. If it gets too big, it should be able to split up.
The thing is, today it is not dire enough for people to care enough. When corona was only in china, we were not very worried. When it came super near, it got us worried enough to take drastic measures.
I'm afraid the same will happen with the reaction to climate change. When we feel we could die, we will take drastic measures. No way we will get extinct, but it will cause a lot of suffering and death.
As exemplified in my post above, AMD integrated GPUs don't have unified memory, at least my 5000 series I bought in 2022. Maybe the new 7000 series changes this.
> Well, it sounds like you could come up with a set of useful heuristics, like living next door to the property.

This is a political problem, so it recurses quite a lot. Whatever set of heuristics you come up with, someone will object to them because they will be losers if we use those heuristics. Then someone will object to the composition of the committee that generated the heuristics. Then someone will object to the system that system that came up with the committee....

Of course, we should try to figure out solutions. But these are "wicked problem" [1]. Solutions are not easy to come by, and there will always be objectors. You can't turn this into a well-defined technical problem with a well-formed solution.

[1] https://en.wikipedia.org/wiki/Wicked_problem
Is it recommended to run my own proxy then, and is there any boilerplate project out there? I could also use OpenVPN, but seems like I just want to proxy ipfs, not my whole connection.
> Saying you can retire at 50 if you choose too, and working is a choice, is completely bogus. You are not being nuanced, you are being misleading.

Perhaps read again what I wrote. I explicitly stated that those who still work at 70 rarely do this by choice. More concretely, the lady behind the counter at Walmart is 75, and she definitely does not do that job because she loves it so much.

This was to contrast with the comfortable situation that we in tech are in. We can choose to retire early, even if it comes with lifestyle impacts. Not everybody desires a penthouse in downtown. And not living there does not mean you are living on the street.
Disagree. Generally it’s porn/restricted content as the driver. If Reddit to better monetize the Platform decides porn/certain popular conte t has no place. Another similar to Reddit platform will emerge to host this less than above board content. That will in turn drive other topic discourse and eventually the downfall of the old.

See Snapchat for sexting. Instagram for insta-thots (Facebook has parents these days on it), and YouTube which originally was used for hosting copyright infringement (still is).
There are other ways to consume nicotine which are much less harmful.
> Third party clients seem to be fairly niche with limited usage

The question is: Who is using these clients, specifically?

1. Visually impaired people. The official reddit app has terrible screenreader support

2. The longest-term & most dedicated users to the site, who are responsible for the content that everyone else uses & who want a) ad-free browsing; and b) a better experience than the official app, which sucks

3. Moderators who require better functionality on mobile than what the official app gives

These are all communities that matter a lot, even if it's a small % of users.
I always thought using e-mail in this would be good for systems that occasionally need a human in the loop. Normally one service processes and mails results to the next, occasionally something is forwarded to a human, who can make some decision, edit the mail, then forward it along back into the automated path.
> It's better to know you just need the right compiler than the think the issue is something else as you can then work on building the right compiler.

You completely misunderstand the sufficiently smart compiler objection. It is about dodging real problems by proposing magic solutions.

You can't make C/C++ a safe language "just" by writing a sufficiently smart compiler. It requires a new approach and perhaps even a new language like Rust.

> It touches on proposed solutions such as street-level development votes.

That is not a generic solution to the vetocracy problem. That is a specific identification of a group of people that the author of the article believes should be endowed with making a particular decision. There is no general framework proposed for selecting such a group of people in the general case.

Let's consider some possible general mechanisms. The "simple" problem that we "just" have to solve to make the authors otherwise perfect solution work.

We could endow that responsibility on a single individual, such as the author himself. He feels he made a good decision in the street-level case, maybe he can do the same for other cases, like mining rights or cross-country oil pipelines. So whenever the question comes up as to who is affected by such a thing we go to the author of the article and ask him to tell us. Kind of like a dictator or even a King.

Or we put together a committee and they decide between them who is impacted. Kind of like an oligarchy. Or maybe we all get a vote on who is impacted. A democracy to decide who is impacted and who gets the right to vote. It's recursive! Or divide and conquer!

It's starting to sound like picking the mechanism to determine who is impacted by a particular change is a very similar kind of activity to existing political mechanisms. That is suspicious. Maybe it isn't an easy problem to solve after all.
That is a non-issue regarding privacy and the intention is to ensure compliance with employee protection laws capping the maximum weekly working time.

You write down when you started working and you write down when you stop. Some employers automatically subtract your legally required break time, some want you to enter it manually.
IMO, society needs to have a long conversation on what function school should provide. The reactions to closing during COVID (which was the right response, IMO) proved no one agrees on this, and I think a lot of our education problems stem from the disconnect between what people think school's role is (parents, kids, educators, administrators, lawmakers...).
So many promising ideas for Dart 4.0 to adopt :)
Perhaps they reached an out-of-court settlement? That said, here's the listing of people with significant control in the UK

https://find-and-update.company-information.service.gov.uk/c...

It has Mostaque as having 75% "or more" and no other directors or people with significant control are listed. Waseem would have to be listed as a PSC if he held the other 25%[1] so if he has equity, it's less than that.

[1] https://www.gov.uk/guidance/people-with-significant-control-...
The Numbers Are In: Elon Musk Has Been a Disaster for Twitter
I'm not sure those days ever existed. MySpace is still operating, after all. I think we may have overestimated the degree to which network effects lead to an exclusive or monopolistic structure - it turns out a lot of people are pretty willing to have multiple active social media accounts, and that there are disadvantages to very large networks (pushing people to spread out into a series of smaller ones). And then there's federated stuff like Discord and Mastodon, where you can use the same account to join many networks, decreasing the modest friction.
it is actually not different than Soviet Union under Staling. So wasn't Staling a Socialist?

Check this out: " LGBT themes and issues faced increasing official government censorship and a uniformly harsher policy across the entire Soviet Union. Homosexuality was officially labelled a disease and a mental disorder in the late 1920s (specifically over a period from 1927 to 1930)." https://en.wikipedia.org/wiki/LGBT_history_in_Russia. People keep trying to avoid call Left by their name. You cannot simply start to call everything bad Right and the Heaven Left. Its absurd.
That's not how business taxes work. You are taxed on profits.
I even recommend keeping separate personal and work phones, let alone real boxes. It's not like hardware costs anything these days, anyway.
Except that the vaccines never stopped infection or spread. Here is a humorous video on it. https://youtu.be/E0Mup2cs6Uw
Well, maybe. I think it depends.

Certainly you can't have your friend Bob who works at Acme tell you stuff then suddenly you're in the clear. That isn't how it works.

But if let's say Bob does something dumb that leaks info publicly, sure - it's public now. You can trade on it.

I'm far from a lawyer but there's nuance here.
Weird that seemingly only the US decided to close their schools for so long though. And the states that did stay closed don't have much better results (if at all) than all those countries who re opened schools by the end of the 2020 school year if they closed them at all. The results basically don't agree with you
Dive deep into Java's ScheduledExecutorService's internals
There are unfortunately lots of software packages that don't offer a convenient passwordFile option in nix and the easiest way to get running is to specify a password in a way that ends up in the nix store.
Man wanted to travel larger distances in shorter time to any place he deemed worthy at any time.

And after a while another man came and said "you shall not, its unhealthy. Take a train, which will bring you to a limited amount of places at certain times during the day. Ah and don't forget to pay your bike ticket because a bike is obviously a person as well"
> Yes, it sounds like it's close to the (legitimate) bogeyman of government intruding on it's citizens for nefarious control reasons.

It is literally the bogeyman of the government, not close to. And I'm not sure why you draw the distinction between public and private speech. Public speech is the most important form of speech and the first thing to be attacked by authoritarian governments.

Declaring that only the government can decide what is safe for us to see is the most authoritarian thing I can think of. To think that because "bullies" and "authoritarians" would try and convince people in the marketplace of ideas constitutes a threat to democracy so we must expel free speech, and therefore democracy itself, in order to protect democracy is some really twisted thinking.

Once you have removed free speech you ARE the authoritarian bully. And in what sense is someone an authoritarian because they are trying to convince you using free speech? Would you consider me an authoritarian because I support free speech?