skysight-inc/HackerNews huggingface dataset:
Interesting to hear from someone who's studied this professionally.

Fortunately a drug that was recently in clinical trials as RBX 2660 [0] was recently approved for use within the US as REBYOTA [1]. It's an improved engineered version of a fecal transplant.

It's actually free even if you don't have insurance although, you have to have two recorded recurrences of Cdiff to be approved. Vancomycin is incredibly expensive, one course WITH insurance was around $385.

I've found a few brands of probiotics work well for maintenance as my recovery continues with some clinically supported probiotics and a diet that avoids trigger foods / too much sugar.

BioGaia [2] - contains L. reuteri which is clinically shown to combat active cdiff

Florastore [3] - creates a biofilm that aids in removing cdiff spores from your gut

BioK + [4] (intended to be used in conjunction with antibiotics to help avoid cdiff / has variants used for patients with feeding tubes to maintain gut health)

At this point, I'm back to being healthy and gaining weight, hoping I don't have serious colon cancer risk factors in the future. Curiously, for those who don't know, (I didn't) when you take Vancomycin you're supposed to suppress calcium intake as much as possible AND avoid any and all trigger foods for gut inflamation.

0 - https://pubmed.ncbi.nlm.nih.gov/36287379/

1 - https://ferringusa.com/?press=ferring-receives-u-s-fda-appro...

2 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607411/

3 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805518/

4 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291414/
I don't think any natural law would be broken if it goes off 10-100,000 years before "schedule".
It's 10M years old after all, nobody would mind if it happens sooner :)
sorry, I said that 9 hours ago... now we're using Bun actually :D
If it did, you'd be dodging a bullet. Sounds like a toxic workplace. "We won't hire that guy because he dressed up for the interview."
> Americans on HN like to pretend that transit is a magical unicorn fairy dream in other countries, especially Europe.

> America has a long way to go, but people who work in this space know that every country has its problems.

Of course nobody is saying transit is perfect anywhere. Hong Kong is expensive, Japan has overcrowding issues (not enough capacity), older systems like Paris and London have relatively frequently breakdowns due to the age / lack newer features like platform screen doors (and retrofitting them is super expensive and long, cf. Paris lines 1 and 4). However, problems on transit in the US are... decades behind, and much worse than pretty much anywhere in the developed world. It was comical arriving at SFO and going to the BART station and seeing a plaque commemorating the mayor/governor/commissioner/whatever for his magical foresight in pushing to have BART go to the airport... something considered common fucking sensepretty much anywhere is being commemorated by plaques in the US, that's how bad things are there.

Yes, Crossrail was massively over budget and late - and of course it was, it was being built in one of the biggest cities in the world which has history and settlements spanning back thousands of years, and had to go around and interface with infrastructure going back more than a hundred years. Very few American cities have anything even close to that amount of complexity.

> Britain's train system is so dysfunctional, it's being re-nationalized. Train companies are bailing on their contracts because they can't make money. And the entire country is littered with hundreds of abandoned train station and rail lines that were discontinued, cutting off many towns and villages.

Yes, the British rail system is badly mismanaged. It's still much better than anywhere in the US though, in terms of availability, punctuality and price. Yes, it simply isn't profitable to serve every little town, so many had to be abandoned which is sad. Nationalising the system is a good step forward that will probably improve service overall.

> It's also comical that you state that "bulldozing the poor away to build infrastructure" is an American thing, and then turn to China as a shining example. You can't be serious. China has displaced millions of people (bulldozed) because they were in the way of transit projects. If America could employ construction workers for China's meager wages, America would have trains everywhere. Perhaps if it brought back slave labor, like China has, that would work.

Yes, it is mostly an American thing, where most cities underwent bulldozing of the poor/non-white neighbourhoods to build highways. When China does it it's more generic "you're in the way" and not an explicitly racist/anti-poor thing. Furthermore, I specifically talked about China's metros, which are in their vast majority underground, so there was nobody to bulldoze over.
In my limited experience with BSD over the years (I tinker with it every year or so), a lot of the core experience remains the same. Additions to rc.conf should keep working, as well as configuration files for things like jails.
Ask HN: Have any managers/team leads been asked to layoff staff b/c of AI?
I've been asked to start reviewing layoffs in terms of AI automation. The IBM layoffs articles have been passed around executive management recently.

I'm wondering how common this is right now ?
Strictly speaking, those are genetically modified -- just a lot slower -- and through selection, not CRISPR
7-zip does recovery records now?
> it easily may be tomorrow

Tomorrow is in the next 10,000 to 100,000 years.
Watch Ukraine's 'Kamikaze Drones' Slam into Trucks, Tanks, Other Drones
Don't forget unleaded octane ratings!
How about using AI to understand dates? My bank’s CSV output isn’t recognized by Excel and needs to be manipulated so it will follow a date format.
The quality of these systems varies a lot… and so does the quality of the cars themselves. A highly connected computerized car needs bulletproof wiring with waterproof corrosion resistant connectors everywhere. Etc. Try a German car with the factory manuals and software and you won’t have an experience like this.
There are a ton of locals that are born and raised here and are well educated and technically literate to do any tech work. Businesses relocating from abroad to pay 4% local taxes is not a net negative. A lack of real estate or extra foreigners is not the problem with Puerto Rico, there is a distinct lack of population and abundance of homes falling further in to disrepair. You are parroting political talking points by people who would love to push decades of failed policy and corruption on jake paul, and in doing so you're also managing to discredit the majority of professionals in puerto rico.
I think this artist demonstrate your point:

https://www.youtube.com/watch?v=R35N43h8M5U (The acoustic of PVC pipes - Nicolas Bras)
I don't see the guide to run FreeBSD in a container from that man page.

And what about if my Linux Distro doesn't use system-md, like Slackware.
I think we are seeing the effects of a supply chain strain around battery production.

GM is killing the bolt in favor of trucks. I'm sure they'd still want the bolt but likely trucks are more lucrative and batteries hard to come by.

My guess is 10 years before that battery crunch eases up.
It doesn't have to be mutually exclusive. Metabolic syndrome causes all sorts of general havoc with just about everything you can think of, which would probably include neuron's ability to maintain homeostasis or fight a latent infection.

Most everyone (at least older people who never got a chickenpox vax) has a latent varicella zoster (the shingles/chickenpox virus) infection, but only a minority will get Alzheimer's. It could easily be true that varicella is causal in most Alzheimer's, but also that many of those cases would never have happened without compounding risk factors like metabolic syndrome.
> The entire rest of the world, including Teslas outside the US, use CCS

As stated elsewhere in the comments, the European CCS charger and the US CCS charger are not the same.
(A) To suggest that the lack of effect in men is a statistical anomaly, and that there IS an effect we're not seeing.

(B) To suggest that the effect in women is a statistical anomaly, and that there's nothing there but a fluke.

These things, from the data, are approximately equally likely. Because there was zero effect in men -- in fact, men who took the vaccine were apparently more likely to be diagnosed with Alzheimer's, though this trend was extremely slight.
Imposing financial discipline is one thing. Mistaking ephemeral "brand value" for engineering prowess and reputation (typical of marketing-oriented mgmt), as cited above, is quite another.

Being required to optimize for another real-world constraint (i.e., cost in this case) is more work, but ultimately just another task for an engineer. Being required to not engineer greatest-practical-stuff, but just slap the name on some junk is not the same thing, but marketing people can't see that, even though customers can.

I'm concerned about the Chinese ownership, but that seems murky now, since NEVS bought a stake or strategic partnership, then got bought 51% by Chinese real estate conglomerate Evergrande, which is deeply in debt, and NEVS is now in "permanent hibernation mode", essentially liquidating. I wonder if there's opportunity to get it back in control of democratic nations. Anyone have deeper information?

[0] https://en.wikipedia.org/wiki/NEVS
And much like a pomegranate or a crab, half the experience is taking it apart.
Out of curiousity, have you tried activated charcoal? It's not good to take frequently because it blocks nutrient absorbtion, but if I'm feeling really awful or just need to feel clear for a day so I can focus on something important, charcoal seems to mop up some of the toxic metabolites and give me a short break.
Since this is gaining some traction. I'm curious if you are using jails and a jail manager, what are you're using now? I'm still using IOCAGE (Version 1.2) on freeBSD 13, but it seems like its not the best way to do it anymore? Documentation is all over the place on what is the best way to manage jails now.
Suzuki Alto

You can buy it new for 7,300 euros taxes included in Italy.

Full optional.

I change oil more or less every 20,000 kms, which is more than two years driving for me.

I change it myself, I only need to buy the oil that costs about 20-25 euros for a full change.

Other than that, the car is basically maintenance free.
I don't think that is the case anymore. I think it also was platform-specific before and only applied to Linux. But I couldn't find the exact change with a quick search.
My local grocery store had them for a few weeks but doesn’t stock them anymore. A shame, because they are delicious.
There are a lot of jail tools these days, it would be nice if we posted more modern FreeBSD guides.
Myself I use BastilleBSD heavily for personal and small business use.

https://github.com/BastilleBSD/bastille
and soon to be the mobile information gathering platform that google has always dreamt about. while removing the niceties of car play.
At this point, given the state of module loading on node and other ecosystem problems, my reasons for switching to deno (or bun) are dwindling.
Just to echo what other people said, the people who put American citizens of Japanese descent into prison camps were unambiguously bigots, and a lot of that was based on people wanting to assert that the United States was for white people (contrast with the much softer treatment of American citizens who were ethnically German and Italian).

The fact that some of the political leaders who approved that did other things doesn’t mean we shouldn’t hold them accountable for a venal act – I would argue the contrary since they’re otherwise praised and it’s important to remember that our heroes are not perfect and should not be copied without improvement. One can make similar statements about how, for example, programs like social security or the GI bill were both good for many people of lower class backgrounds but also carefully designed and implemented to benefit black people less than white people.
Yeah, roughly the cost of a leaf, better range, and not ugly. They were close to the perfect commuter cars (I very nearly went with the Volt, but went with a model 3 in 2018 instead.).
Yes, a few objections, or at least requests for clarification.

You propose that necessary conditions for "spiritual" are "consciousness" and "empathy". These phenomenon are regularly seen in trees, and also in most motive forms of multicellular life.

You then propose that sufficient conditions would additionally include existence of an ego AND its dissolution.

If ego is the thing that gets in the way of spiritual, then wouldn't beings that don't have ego be inherently spiritual?

And for those beings that have an ego, given that the ego is made from the non-ego, how do you distinguish between when they are spiritual and when not? I've found that my self is often less aware of my spiritual aspect than I would like, but I'm also very seldom aware of how I coordinate my heartbeat or how I breath or digest food.

How do I know that I'm not enlightened? And just because I "know" this, does it make it true? Does it matter more if I believe in God or if God believes in me? What is this barrier between me and enlightenment? isn't the ego just as much an expression of "spirit" as the heartbeat?
I'm not sure where you get your information but it is quite true that well-heeled Americans have sold out on the mainland and moved to plush locations in Puerto Rico over the last ten years to escape not only taxes here, but also what they see as the coming social disruptions that will place them and their wealth and family's safety at risk. Several who previously ran their newsletter empires from DelRay Beach, Florida or similar locations based on the US's SE penisula. (LOL)

For them Puerto Rico is the perfect place to be to retain their American citizenship, eat fantastic food, enjoy an awesome lifestyle at a large discount, while avoiding tax liabilities.

Libertarians who operate investment newsletters have been touting the advantages of selling out here and moving to PR for years. They are not alone, as pastor_bob notes there are plenty of other people with the means and the opportunity to flee the mainland so they can watch it burn down from a distance while still enjoying the benefits of citizenship but in a more tax-advantageous location.

It was actually pretty funny reading their bitching about the state of things on the island after Hurricane Maria. Motherfuckers actually had to endure hardships getting their internet access restored so they could publish their rags and then they filled them with gripes about what a hardship it was dealing with the disaster even though they kept themselves isolated in their compounds so they never saw the true scope of the devastation that PR natives endured.

Fucking Grifters.
Well there’s more than just Node and Deno too. Cloudflare workers, etc. If you want portability across different worker runtimes and not just Deno, you’ll still want to avoid heavy Node API usage.
AI and the Hard Stuff
Genuine question to all concerned about PE ratios. Why is PE not subject to 'new normals'? A lot of people seem to reject stocks because they're 'expensive' which to me seems like a relative term. There are a lot more retail investors out there now.
The 2^n idea is just a thought experiment, but you should be able to realize linear or close-to-linear speedup using a communication-free algorithm that shards the search space evenly across available cores, no? I don't see why this strategy isn't more widely used.

I can see how continuity accelerates the search for solutions, but I see that more as an orthogonal property, not a limitation of parallelism. Even if your domain is continuous, accelerating gradient descent is nontrivial, and many discrete optimizations problems benefit from parallelism.
Deno is moving into a similar space as Kotlin started at by adding all this interop—they're trying to be the "better Node". Meanwhile Kotlin is frantically trying to differentiate itself because Java is closing the gap, but it's hard for them to do because they've spent so long piggybacking on the Java ecosystem.

Deno is very vulnerable to the same fate. Yes, it's easier to get adoption if you can plug into an ecosystem that is already popular, but then it's not your ecosystem and the behemoth that actually owns the ecosystem will feel the threat and adapt.

If you don't prioritize interop, your initial adoption will be much much slower, but if you make it out of the early stages you have an ecosystem of your own that has its own distinct advantages. The incumbent can't just pull in a few good features and thereby take your mind share.
India would block strong statements against Russia and inhibit cooperation that benefits the rich world over developing countries. The G7 is essentially just a club of western-aligned rich democracies, and India isn't two of those things.
India has little interest in aligning with the west, and little to gain. They are going to continue with a third path, or possibly creating their own block in the future.
can you give some examples of systems to try implementing?
> It's optimaly located for a 100% solar-PV system (see South Australia for comparison)

How does it compare to South Australia? SA reaches from 38-26 degrees of latitude, with empty scorching desert in the north (towards the equator) suitable for mass solar generation.

Puerto Rich is just north of 18 degrees of latitude with a predominantly tropical climate, meaning lots of clouds and rain. San Juan, for example, gets just under 3000 hours of sunshine a year, which is similar to places like Memphis or Oklahoma City (vs. Las Vegas, for example, at 3800 hours).
Having read the whole thing, it comes across as pretty high on the bland-corporate-speak spectrum, e.g.

> "For me, the first big revelation of data science was that data can be a key asset that offers real value. But, the second revelation was that data can be a liability if you're not a good shepherd for it."

Translation: "Targeted advertising has been highly profitable, but it's a problem when your target's credit card numbers, address, SSN, get are exfiltrated to a dark web broker."

> "End-to-end encryption would reduce risks to privacy and keep providers from seeing private messages, but it would also limit platforms' abilities both to respond to law enforcement requests and to perform content moderation."

Translation: "Governments want more power to snoop on citizen's hearts and minds, identify potential subversives at an early age, and control the spread of information, and if we (Big Tech) don't cooperate we won't get government contracts and might be targeted ourselves."

See:
https://en.wikipedia.org/wiki/Dragonfly_(search_engine)
There are many people that feel having Node support harms Deno's goals, but I don't agree.

To me, this is like complaining that you can mix JS into TypeScript projects. The only reason the latter is successful is because you can migrate from the former in a first-class way.

I don't think Deno has the community support to make it on its own steam - that said, I think it's a huge value add in terms of DX. I support them on this 100%.

Node is trying to add in some capabilities of Deno. We'll see which one comes out ahead.
TSMC is cheap because of the risk of invasion, otherwise they would have a pretty insane valuation already.
> What she usually wants to say is: your life sucks, fix it and you will feel better. Go out for a walk, eat healthier food, make some supportive friends, engage in some self-care, meditate, etc.

It’s almost like we haven’t collectively created a society that aims to increase human flourishing and instead of created a living nightmare with the illusion of progress due to shiny new technologies.
You make a lot of good points and it's made me think that there is a fundamental assumption that tests are useful. I think that that is not the case. As you said this test attempt to both validate knowledge and ethics and ends up invalidating itself. It seems to be a flaw intrinsic to this style of test.

I have taken some very well constructed tests. They were not takehome and only one was multiple choice (it was a systems class so it became sets of binary answers which became more than multiple choice). I think that ensuring the integrity of answers in necessary for gaging learnings from a test like this but that need, as you've implied, would indicate that the test is the wrong tool
My grandmother couldnt eat any grapefruit due to he medications, this was a problem because for ~50 years, a grapefruit was her daily breakfast with some salt and sugar sprinkled on top.

To this day - I LOVE grapefruit in all forms... it sucks to think that there may be a time in the future where I cant eat it.
The stability of connecting a fresh XP install to internet and immediately getting exploited.
“If we meet the right shot, this will work. If we get some… buckaroo?…”

He needed someone on the US side to figure out he was defecting and meet him with a plan to help. He gave it 1 chance in 3. Loved that moment you reference when he realizes he did indeed meet the right shot.
> So if you want to review a company, how would you?

So have up to a year after you leave the company I believe.
I'm gonna get my engineers to invent a combustible lemon that burns your house down!
> At the same time, I would also not mind an unmozillad firefox, perhaps in exchange for a certain donation amount per year.

LibreWolf (https://librewolf.net/) is essentially this: Firefox, with the telemetry and Mozilla adware disabled. And you can use homebrew or other package managers to handle updates (instead of getting spammed by update dialogs every day or two in the browser itself).
And vice versa. I really wish the Linux folk would educate themselves a bit more about what is actually available on FreeBSD.
FWIW, the relevant gunk: C:\Program Files\dotnet\sdk\7.0.100\Sdks\Microsoft.DotNet.ILCompiler\build\Microsoft.NETCore.Native.targets

And C:\Program Files\dotnet\sdk\7.0.100\Sdks\Microsoft.DotNet.ILCompiler\build\Microsoft.NETCore.Native.Unix.targets (where the linker is selected)

See the area around and after this chunk

<CustomLinkerArg Include="&quot;$(NativeObject)&quot;" />
<CustomLinkerArg Include="-o &quot;$(NativeBinary)&quot;" Condition="'$(TargetOS)' != 'windows'" />
<CustomLinkerArg Include="/OUT:&quot;$(NativeBinary)&quot;" Condition="'$(TargetOS)' == 'windows'" />
<CustomLinkerArg Include="/DEF:&quot;$(ExportsFile)&quot;" Condition="'$(TargetOS)' == 'windows' and $(ExportsFile) != ''" />
<CustomLinkerArg Include="/LIBPATH:&quot;%(AdditionalNativeLibraryDirectories.Identity)&quot;" Condition="'$(TargetOS)' == 'windows' and '@(AdditionalNativeLibraryDirectories->Count())' &gt; 0" />
<CustomLinkerArg Include="-exported_symbols_list &quot;$(ExportsFile)&quot;" Condition="'$(TargetOS)' == 'OSX' and $(ExportsFile) != ''" />
<CustomLinkerArg Include="-Wl,--version-script=$(ExportsFile)" Condition="'$(TargetOS)' != 'windows' and '$(TargetOS)' != 'OSX' and $(ExportsFile) != ''" />
<CustomLinkerArg Condition="Exists('$(_Win32ResFile)')" Include="&quot;$(_Win32ResFile)&quot;" />
<CustomLinkerArg Include="@(LinkerArg)" />
Agree. A lot of people talking about cures here (and a lot of pseudoscience), but not a lot of people exploring the societal psychological aspect. I've noticed a lot of people, especially younger people in America, creating their identity entirely around consuming things that are short-lived trends. It really leaves people empty once the tide goes the other way. It's like systemic insecurity. I'm wondering how fostering more concreteness in our culture (as well as workplace structure changes) could help with this, but I have no idea how to approach it from the ground up.
Those .xlsx files aren't just blobs. They're ZIP files. If you want version control for Office documents, it's as easy as unzipping them and checking in the results.
Funny how we call bad cars "lemons" and there is a car called 'Citron'