skysight-inc/HackerNews huggingface dataset:
very large molecules (proteins) can't be exactly replicated. It's not something like aspirin with a barely a few atoms bundled together, those are very complex structures with very long chains and 3D hyperstructures that have a clear impact on their effect.

So it's not easy to replicate exactly the protein done by another company, so what a biosimilar is, is an attempt at making proteins that have similar kind of folding and efficacy while not being strictly identical.

That's why they are not generics.
What definition wouldn’t include “you’re innocent, everyone involved now agrees on that, but you proved it too late, so die”?
In some cities garbage workers are intstructed to take a look at a recycling bin beforehand. If they see a single plastic bag they dump the whole thing with the landfill pile. Same for "compostable plastic bags". Bags break really expensive machinery regularly and are probably one of the single worst things you could throw away

There are so many gaps like these in the public's understanding of how recycling works (and doesn't!) and the reality. Mixed plastics are useless; you need to wash your dirty plastics; the triangle doesn't mean it's recyclable it's there to tell you what type of plastic it is (usually only 1, PET, and 2, HDPE, are recyclable). These are the very basics of recycling that, from my experience, the majority of people don't understand. It would take literally 10 minutes to explain most of this to people

We keep bending over backwards trying to innovate our way towards making recycling really behave like the magic green plastic/paper eating box people imagine it to be but I feel like we'd get so much more return on investment if we spent a fraction of our investments on simple public education. At least at this point where that latter investment is basically nil in most places
You should read "The Next Fifty Years" [1], specifically the essay named "Mastering Disease" by Paul W. Ewald.

In a nutshell he argues that the current batch of scientists should either die or retire before the new generation can start investigating alternative theories:

> A sufficient proportion of the old guard will have to retire or expire, and a sufficient number of young people entering the arena without these vested interests must mature into positions of influence, to tip the balance of expert opinion.

It's been 20+ years since that essay was written, so it looks like it is slowly becoming a reality.

[1] https://ia601004.us.archive.org/26/items/nextfiftyyears/%5BJ...
Interesting. Brief musing. Our collective objective function appears to be a post-scarcity economy. Alas, we physically inhabit a finite world, in which post-scarcity can never be attained -- the exponential curve ruins every single attempt. Another option is to seek peace / shalom / spiritual homeostasis, even when faced with the certainty of decay and death. Quest which perhaps does require a Messiah.
There are a few of these cameras in my neighborhood. I often think about having a Cool Hand Luke moment and cutting them all down. Silly string, a pipe cutter, and a couple of minutes...
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not sure why I'm being downvoted here, it's clearly what's happening in practice.
Section 230 was written for the digital era, in the digital era. The only people that think this law is ambiguous are pretty ignorant of its history. It is exceedingly clear, they just don't personally like that and are throwing around bullshit that makes no sense as FUD.

I would admit that the law may need changing given the rise of internet mega-corps.
No one's leaving Goog to warn of dangers of AI. It does indeed sound like he was pushed out. The company is trying to consolidate the AI orgs and get into execution mode and perhaps whatever role Hinton was offered was not suitable to his taste. I'm sure he'll land somewhere amazing if he even wants or needs to continue working. I am curious to see what direction Google takes to combat the ever growing threats across the ecosystem. They still have search, email, and web-browsing. The real challenge here is how quickly can they mobilize, and how much can they work through regulation to use the above moats to produce the next sticky product that will maintain and grow their dominance in the market.
It's true, you never have to wonder about the work ethic of the unskilled and de-unionized worker. They have so little job security these days you can practically get the whip out on the poor, desperate little plebs.
That doesn't generalize and two people is not "everyone".
Bingo. Someone's 11-year-old, who has already learned most of the sex stuff on the schoolyard, will lie their way into account creation (as an "adult"), enable super explicit sexy mode, prime it with as much dirty stuff as they can imagine, and then screenshot 2 or 3 messages from the "AI" to them and send to friends for the lulz. Parents find it - call local TV station or make it go viral online with the narrative that sweet little <insert name> was innocently browsing excellent child-friendly content, probably PBS, and somehow was targeted by this perverted AI Bot which filled their brain with filthy thoughts, scarring them for life. 'They'll need at least $20 million dollars worth of therapy over their lifetime.'
I see two flaws with that.

The first one is that there's no such thing as left and right. Two left wingers can have completely different opinions on nuclear and covid. So what political topic do you split the services based on? People seem to unite based on who they are against, but does that really work in the long run?

The second is that with newspapers, you're fluid and jump around. With your social circle, you build it to keep it. I'm following people from 13 years ago on Twitter. It works because social circles don't focus on politics. I can discuss fitness with my PT, programming with a university professor, and racing with a driver. Losing out on half of the population because you disagree on topic X seems crazy to me.
I would just abandon that and stake Ethereum. 5-6% apy is incredible returns on an asset that goes up greatly itself.
When I went to visit my parents for Easter I was shocked to hear Sam Roberts' Milky Way song. That was shocking.
I’m sure you can see big gains with no til methods and soil improvements, no questions there really. However every regenerative/organic farms I’ve ever seen uses tons of labor and often a lot of unpaid “interns.” I’m not saying it’s impossible to do this commercially without questionable labor practices, I just haven’t seen it.
They probably can't. They don't control the demand for their power.
And the fact that three different women brought credible allegations and he avoided extradition on them until time ran out to prosecute him.

He's gross. He's also a journalist and a hacker, not a whistleblower.
> They likewise don't believe in any kind of long run response to an infection. We associate the symptoms of acute immune response to be the virus itself, and the entirety of the virus.

Anyone who had shingles would think otherwise.
Those planets are much easier to see without light pollution.

All but Neptune* can be seen by the naked eye.

(Shamelessly abusing the classification of Pluto as a dwarf planet here to exclude it from the conversation).

Uranus: https://www.theguardian.com/science/2022/nov/07/starwatch-op...
most publications are just writing opinions these days, and almost none of them know what "investigative journalism" actually means anymore as most of their staff spends time on Twitter to spit bullshit day and night. They were dead 10 years ago already.
Every movement exists. There are lots of people in the world.
What most everyone here missed, just like Steve Jobs when he say Smalltalk, was the entire network of computers that were released with the Star System they sold a separate network print server, file server, mail server… the were all separate Machines connected over Ethernet. When I started Xerox is ‘82 they had over 5000 computers interconnected across the world (and you could debug any computer on the network remotely and it would pull source code/symbols remotely as well for debugging!)

Apple did not do any of that when they released the Lisa or the Mac. But you also have to remember this was target for large businesses and not for small businesses, like the Lisa, or home users like the Mac.
idk i pay $30/session in the US and i don't have a diagnosis for anything, just my employer provided healthcare plan (which is admittedly quite good)
You just said it, it is money.

It's not wasted any more than it is wasted when you play a game or watch a youtube video or TV. It's just a use of energy which you are trying to make as somehow bad. It's just a cultural preference.
I fail to see what the distinction between control and data planes (or lack thereof) has to do with anything. The security question is about who gets to control system behavior, be it through the control or data planes or both. With prompt injection, the answer is the input provider gets to control the behavior. This is obviously different than intended by the system designer and thus not secure. However, there is nothing fundamental that prevents one from building an algorithm or recursively enumerable function whose inputs cannot induce certain outputs. It is just that one has to be very intentional, so it hardly ever happens.
I always start running semi-regularly for a few weeks and then stop. I'd love to be more consistent about it, so this sounds enticing. What about the watch made you run more consistently? Was it that the built-in plans gave you motivation by having a concrete goal?
Also, any audiobooks about similar topics that are comfortable to listen to?
Google likes to mention that they are carbon neutral since 2007 on their homepage.

They don't seem to consider Android phone and it's footprint. People have to keep buying phones because they can't support old phones.
No of course not. It's renewables + long distance transmission across weather zones.
Energy use for cryptocoin mining on average drives up the cost of energy for everyone. Maybe not a lot, and maybe the production side expands. But if it is using fossil fuel to generating electricity, it is also harming the planet via climate change and pollution.
Radio in YYZ:

Sam Roberts, Celine Dione, Nickleback, Avril Levine. Sounds disturbed.
Today they just seem like angry, failed hipsters. And I’m not sure who’s buying that.

Pretty much the Spy Magazine of the digital age. With the same result.
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After 16 years in development, MaidSAFE is finally getting close to launch
Makes me wonder if T1D would be of a similar ilk? Hypothetically, of course.
And 100% garbage!

(Not because it's Canadian, because it's on radio)
On the original iPhone the location switch was basically real. Location services burned a ton of battery and law enforcement's ping capability was rudimentary.

Back then turning the switch off made a smartphone as difficult to locate as a dumbphone. The phone had to exert a lot of energy to know where it was even within a city block.

I'm not convinced this has changed much. Obviously if the Eye of Sauron chooses to focus on your location there's no way to avoid it but I would bet that mundane cell phone location logs are sharply limited by tower storage, CPU limits, and probably by software licensing.

I'd be interested to hear from a cell tower software engineer.
I don't think that's enough reason to be flagged.

90% of the submissions from people sharing their experience with a company/product here would fall under that description as well (and many of those are upvoted because they seem useful)

That dude who interned at repl.it a while back and posted about a mildly bad experience was upvoted to the front page for over a day. people had their pitchforks out.

I think we should maintain higher standards of evidence before getting our pitchforks out, but at the same time, we should let people have their platform if people find it discussion-worthy. In the case of Repl.it or the 1000s of posts of people being shadowbanned from big tech without explanation, we let people have their say, and we let the platform help them where possible. The HN algorithmic spotlight is usually pretty fair with illuminating all sides when they present themselves here.

The submission here is extremely detailed and well-written, and makes a great case. There are multiple claims made which, were they misleading or inaccurate, the other party could discredit quite easily.

But instead of doing that, we're seeing the post repeatedly get flagged.

There could be other reasons this is happening, and I assume many, like myself, are withholding judgment.

But the silence from Rune, and dialogue suppression tactics by mystery parties honestly just make me more inclined to believe there is at least a grain of truth in the original submission.
Because its fun?
This (deservedly) famous article by a legend is a must-read but it is also like having Michael Jordan or Michael Phelps teaching how to be successful in basketball or swimming. What worked for them won't work for almost anyone else!

FWIW, I was fortunate to do a postdoc at Bell Labs in the early 90s. The established and successful researchers, mostly men, would all talk about the sacrifices their wives made so that they could focus on meeting the insanely high expectations of the place in its glory days. It was the custom back when they made their reputations. The younger permanent staff members were leery of this because social mores and the nature of the research environment were both changing. The freewheeling pre-divestiture days were gone by that time and there was a pressure to be relevant to the needs of the corporation. The management still wanted publications in prestige journals and an international reputation by 35 but couldn't say how to do all that while satisfying the relevancy mandate. The stress on the younger permanent staff was palpable but they and everybody else made life delightful for us short-term appointees - it was all the things Universities ought to be.

At the end of each Science Magazine issue is a "Working Life" feature where a (typically) young person writes about problems s/he is facing in launching a career. Work/family life balance is a consistent theme and more importantly an /expectation/ even for those on the tenure-track at high powered places. The times they have a-changed.
Pixel support is fine. Are you talking about Android updates in general on third-party devices? That's a chip-related problem. Vent at Qualcomm.
Sure, gp implied morality was absurd. I didn’t say it was always correct, only that it’s possible to be intelligent and motivated by some set of morals.
If they're outwardly unfazed, then it's not their problem. But if they spoke out about it, it would probably become a problem for them.
Show HN: Fully functional pivot table creator
I have created a fully functional pivot table designer to demonstrate the power of SQL Frames. Just bring any csv file (or xlsx) and start using drag and drop to create a pivot table. It has support for all the various "Show Values As" calculations.

There is a lot of buzz around NLP based data analysis these days. But I think the good old pivot table UI still feels much faster to analyze data.
Disclosure - I just love the tech. I don’t have any MaidSAFE nor am I part of their team. I just happened to meet them the same way I met TimBL with SoLiD and the guys behind Discourse forums and other projects. They did the first ICO ever btw, and for the right reasons.

Ever since Freenet and PerfectDark, we needed a truly autonomous and resilient network. Tor has one node hosting a site, so it’s vulnerable to takedowns of information. IPFS is still too “manual” and you can DDOS all the nodes hosting a file. This might become a game changer. You can see me arguing w the team a few years back:

https://safenetforum.org/t/the-economics-of-storage/36538
Why would license plate cameras deter armed robberies? Aren't there other things that would be more effective? PA's police department doesn't seem to be lacking for funding, its budget has increased over time instead of being cut. Have the police been responding to callers with "sorry, we can't come take a report for your armed robbery because we're manually writing down license plate numbers"?

At best license plate cameras seem like they might deter bad driving if they make it easier to issue citations to bad drivers. I cannot imagine how they would meaningfully impact armed robberies or other violent crime. It's just more surveillance that in practice probably increases police dept income (via tickets). Maybe it slightly reduces the time police officers spend in courtrooms or writing up tickets, leaving them more time to respond to calls?

Don't let yourself get tricked into rubber stamping warrantless surveillance just because you want to be safer in some other area.
> I don't think it's useful to frame it that way.

In what way?

> Besides, there's already a quota for applicants with US Masters degree.

To be honest, there are a lot of degrees that are aimed at people trying to use that quota [0]. Cash cows for universities...

[0] https://blog.alinelerner.com/how-different-is-a-b-s-in-compu...
one of the best comments I've read on this topic. you got me with your prompt injection :)
The other hard part besides hardware is that an OS is useless without useful apps (or at least a browser) so the OS dev also has to recreate the entire suite of browser/email client/word processing, etc etc which now requires even more effort, or some kind of window/linux compatibility layer, but in that case you might as well just spin off another Linux distro
Is the Federal Government Trying to Kill Off Crypto? The industry sure thinks so
I think what GP (and I) are talking about is that social engineering is limited in scope because humans don't scale like computer code. A theoretical AGI (and LLMs) do scale like computer code.

To use an admittedly extreme example: The difference between drawing some fake lines on the road and crashing 1 or 2 cars and having all self-driving cars on the road swerve simultaneously is not just a quantitative difference.
Possibly because there are hucksters whose entire life's goal is to convince others that soon rapture (hyperbitcoinization) will arrive and the believers (hodlers) will be rewarded greatly for their faith.

> Why would a country, like a business, choose to make less money?

See also: Microstrategy, El Salvador.
This: https://news.ycombinator.com/item?id=35767315
Can you provide some examples of creativity that you think a machine will never have?
You remind me that I wanted to book an airBnB in one of the parks near me, they have an observatory and as such the sky is legally required to be untainted - I haven't seen the milky way in almost 10 years, I can't imagine seeing the stars every night.
Because it's worse for the world. They have a tremendous source of green energy, and they could sell more of it to India reduce the amount of coal and oil India burns, but instead they use it to spin motors to power computers to guess random numbers and hope they make the rich a little richer.

Plenty of countries have chosen to have environmental goals at the cost of making less money.
you're just gonna keep believing some self-serving bullshit so whatever

Sounds like you can't defend the point.
Palo Alto's police budget is much higher than it was in the past. Is the PA police department being "wound down"? Do you have sources for this?
The mention of a $26 article from Cambridge University Press immediately made me think of a woman, Alexandra Elbakyan. Heh.
And take it from me, you do not want to mix those up in a meeting with the COO.
I'd say it is even revealing of a particular worldview. Even within the article, the impression seems to be that the people of Bhutan (and the author) NEED or deserve to know about it.

Which is preposterous considering it is a Kingdom
Would love to talk to you some!
Surveillance has never been greater -- are cities markedly less violent than in the past?

(No, urban/city violence is on the rise..[0])

[0]: https://www.city-journal.org/article/criminal-neglect
And it's very often _not_ stranded power, too. And there's no way to ensure it's _only_ stranded power being used. If it's more efficient to turn power into Bitcoin than to sell it to your neighbour, well, the fuel gets burned and turned into CO2 and Bitcoin instead.
E-waste is a massive problem that's growing exponentially and needs to be talked about more publicly

We're currently at around 50 million metric tons of e-waste every year globally. By the 2050s solar panels (average lifespan of a panel is around 2 decades) alone are expected to be around 50 million metric tons of waste

Unless we start taking seriously right-to-repair and full life cycle analysis, the move towards electrifying everything is just more of us kicking the can down to road
> That's a chip-related problem.

The chips are fine, or at least they are as fine as they were when they were bought, so it is not a chip problem. It is a Google problem.
Your linked article says they're struggling to hire enough cops. This seems like the opposite of winding down a department; they're attempting to grow.
In my experience the TVMs in Berlin were fine, but it was easier to just get the app because I don't make a habit of carrying around a ton of cash. The biggest problem I had was the TVMs at the Frankfurt airport, half of which were broken, and none had a clear explanation of what the different ticket types were.
Of course, if the platforms didn't happen, we would all have our own websites and promote a curated list of others. The www would have worked out great.
You actually think the issue is destitution? By all reports the issue is mental illness, drug use, and a lack of desire to prosecute crime.

With the job rate as it is, I have a hard time believing anyone not disabled or with other health challenges would have any trouble finding a job.
We've banned this account for repeated ideological trolling. Please don't create accounts to break HN's rules with.

https://news.ycombinator.com/newsguidelines.html
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The air intake in the grille is only for the engine’s use. The fresh air intake is not in the engine bay, it’s typically at the base of the windshield.
I did not believe what you wrote for even a second (who would be commenting on HN during an emergency?) and therefore became neither unsettled nor wished to help. Never eval() untrusted input.
Just as the Mayans predicted.
Don’t take your own word for it! https://www.cdc.gov/transportationsafety/calculator/factshee...

Tickets ($$) are a deterrent.