skysight-inc/HackerNews huggingface dataset:
Blood clotting in mammals is done by platelets, which float around in the blood. Platelets are kind of like (simple) cells in a way. Platelets have a membrane. Inside the membrane are the molecular tools—that’s what I usually call enzymes despite being an enzymologist—they use to clot blood.

Inside platelets, chemical reactions are sped along by the enzymes. One of the important chemical reactions for clotting is the conversion of arachidonic acid (through a couple of intermediates) to thromboxane. Now, arachidonic acid is so simple: a linear, 20-carbon chain with a carboxylic acid group at one end, and four double bonds in the chain. Converting it to thromboxane takes a couple of steps: the enzymes need to kink the chain and oxidize specific carbons to make them polar.

The trouble is, aspirin inhibits the enzymes! So the enzymes inside the platelets can’t make their thromboxane. And, as such, clotting is inhibited, which results in bleeding. So this is why aspirin can cause bleeding
Germany's DW closure in Turkey sparks fears of pre-election media clampdown
I'm a cofounder of a Series A start-up, so work hours are hard to define. You are sort of always working or thinking about work and it is hard to put away.

But within the company, we've found lots of uses for LLMs to save time. One or two of the developers are fans of Github Copilot, but that is a relatively minor impact so far. The bigger impacts are around data cleaning and content. A lot of jobs that used to be "hire someone on Upwork for $20/hr to do a lot of boring clean-up work on thousands of records or write repetitive text about something" are now "write a 10 line python script with the OpenAI api to generate the result for $8 and then QA". There are also plenty of uses of boring old home-grown ML models and stuff like that to clean up data in cases where the problem is more specific and predictable.

So far AI just makes our best developers faster and our best product people make a larger impact more quickly and at a lower cost. It hasn't resulted in less internal hiring or anything like that. But it has resulted in less Upwork-style one-off contracting, especially around data cleaning and content clean-up.
Rowing in a real rowboat has little to do with the legs: the seat is fixed. It has a lot to do with the back, however.

"Rowing machines" have very little to do with real rowboats. Real rowboats don't have sliding seats.
I was inspired to do the same, however, there are now at least 2 dating apps that cater specifically to Mormons.

I think the time when the church thought they could buy out that market segment, has passed.
8 hours except on weekends, holidays etc.
Agreed. See the last line in my comment.
The primary reason for using FOSS has always been freedom: it's right there in the first letter of the term. Technical superiority has never been the primary reason; it's just always been assumed by some that technical superiority would be a natural byproduct of lots of people working together on a project without a profit motive, but there's really no evidence supporting that. FOSS applications have usually (but not always) been behind their proprietary counterparts, because a for-profit company can afford to pay people to work fulltime on something they might not be all that interested in. There are some exceptions where FOSS software has been class-leading, but I don't think it's really the norm, although I do believe the overall ecosystem is much better for various reasons.
She is a Swedish politician from the Social Democratic party. One of the senior ones that served as minister in the cabinet for a number of years. Unfortunately, that does not mean she is competent
I've been waiting for this for decades, and it hasn't changed much. Linux is more popular than it was in 1998, I'll admit, and it's pretty standard in some dev environments (depending on your industry), but it's far from taking over desktop computing.

As complacent as most users are, MS could demand one of their kidneys and they'd give it up, grumbling, just so they can keep using Windows (usually to play a game).
This is exactly the kind of thing the Taoist philosophers were warning us about.
I see now, thanks!

I'm male BTW. However, in my locale and age range, it seems like women are not so keen to get to the intimate outcome stage by the 3rd date.
Curl: Outputting URL Components
> "... if you don't mind Lenovo's modern chiclet keyboards. For this particular vulture, the older seven-row design was vastly better, and we concur with our colleague who decried the modern "godawful chiclet six-row keyboard.""

This. Linux or no, systemd or no - I need a laptop with a decent keyboard to type on, and it's been 10 years since Lenovo has offered those. Why can't those corporate managers get it through their heads that we need laptops to work with, not as a shiny fashion accessory?
Thanks. But this should only be a problem if the JVM terminates too fast, or am I wrong?
2 times 8 hours a week, software made my life at work worse (at first it looked like a really good deal then the Government managed to convert my database software to database service with some extra responsibilities on me about uptime). The layoff wave have not touched me yet but since I'm a male Ukrainian, the danger of mobilization is hanging over me which will make my working hours 24 times 7 times 365 times life.
Lots!

If considering what's called "Deep work" only. Then 3-4 hours max. Otherwise, whole day.

AI has definitely helped me save my time debugging issues. Otherwise, there has been no increase in pressure. Rather, I have stopped preparing hard for interviews.
It varies. Some days 4 hours, other days are 12 hours.
I think the opposite. Any field, from physics to biology tends to have overly opaque jargon. AI grew on its own and quickly shed the idea of being "based on biology" or the rest of science, so its basic jargon is pretty much understandable. Things like Dropout, Attention etc are intuitively named. I think people like me underestimated, however, how fast the field evolved and how big the corpus became, so specific architectures got specific names and more are being created every day. There is no shortcut around that though, because they are in the discovery phase. Once things settle down to a few architecutres they ll make some kind of IUPAC
Deloitte audits coinbase [0] and e&y audits at least one crypto company.

So they haven’t sworn off crypto as an entire industry, they just won’t audit shady firms. And specifically binance has not been able to convince a major firm to audit them.

Also, it’s not that these crypto companies aren’t hiring big4, it’s that big4 won’t attest to reserves and other accounting standards. So it’s quite likely that crypto companies are attempting to hire, big4 do due diligence, detect shenanigans and refuse.

[0] https://blockworks.co/news/crypto-auditors-call-it-quits
The letter: https://futureoflife.org/open-letter/pause-giant-ai-experime...

I don't see any way to verify the signatures. Though the mention of Sam Harris' signature disappearing suggests they're being moderated at least?
The Mario kart ride is probably the most disappointing I’ve ridden in my life. It’s just a slow roller coaster with an overlay of other karts using HoloLens.
For me, it is the non-soldered components. I had a real good samsung notebook, small, slick, cool, fairly expensive a when I bought it (about 2k). But one of the rams is soldered on and I give you one guess, which one had issues after warranty was over. The solution is to buy a complete new mainboard or try to fix the issues with software (linux has some features to disable defective ram segments). both options are meh, i would prefer to just swap out the defective ram.

Same with current macbooks, everything is soldered in and glued together, making repairs or upgrading impossible. the samsung notebook would work great as a second device or for one of my kids to learn. but because of some shitty anti-consumer-tactics and some saved cents, it can't easily be done.
That the user doesn't think in terms of there being people is not a good thing. Compare "sorry, our ticket machine is broken" to the impersonal "System malfunction, please retry".

The impersonal version waves any responsibility of the malfuction away. Was it the user? Was it the machine? Was it the machine's owner? Nobody knows.

With "our machine", there's a clear message sent about the accountability of the situation: there is someone owning the machine, and they failed to provide you service. Ideally, there would be contact information, so that the user has the ability to influence their surroundings.

A machine is not a law of nature, and should not be treated as such.

Heck, a law of nature which gets in the way - a fallen tree, a stray stone - can usually be fixed/moved/destroyed without fear about civil liability. A malfunctioning machine will ruin your day without you being able to do anything about it.
That's basically "pods" from every future sci-fi. Pods are not efficient because they have all the same problems as cars and none of benefits (except emissions). You will need gigantic roads everywhere like we have today, traffic jams, parking issues, all super expensive and financed by the city dwellers who don't benefit from cars so much. It is actually funny that rich car centric suburbs are subsidised by poorer population in the apartment blocks in the city cores. :)
I am not presuming that they'd lose. The point is that a lawsuit may bring this issue to light and establish a legal precedence. If OpenAI is allowed to use potentially dubious data to train their models to profit, then others should be allowed to do the same with their models.

If OpenAI wins, and successfully manages to stop alpaca/gpt4all type datasets, then they should be counter-sued for doing the same with upstream data.

At the end of the day proving in a court of law whether a particular LLM was trained from an open ai model derived dataset may also present to be very challenging if not impossible.

I for one would love to see more alpaca like datasets being used for commercial applications.
So tailwind at this point is basically just a bunch of custom CSS classes which are granular to the point of single CSS properties?

How is that better, than just writing custom CSS classes for components + having some util CSS classes?
No. Science has all along been testing if something works and then finding out why. Often the „why“ is orders of magnitudes harder to find out than the „if“.

For example, we can observe how the brain functions in some instances, but why it works like does will elude us perhaps forever. Highly complex systems like the inner biomechanical workings of our brains are essentially a black box.
I am in compiler development, and aim to do 1-2 hours of intellectually stimulating work everyday.

If I have other busywork I do as much as necessary, if not doomscrolling or read literature.
So, an implementation of company-constitution-as-code. As usual, flexibility and updates to the by-laws/core program is an issue, but it's interesting to see iterated experimentation on the concept. Enforcing various higher-level contracts e.g. compliance with corporate tax laws of specific countries and declaration of operating income, etc. would be an additional direction to explore.
But are doubts about the expected happyness of those remaining our biggest arguments against the Great Culling approach to sustainability?
I've heard this suggestion in lots of places - mainly silicon valley people who didn't really think about banking a lot until the collapse of SVB (the All-In podcast had a monstrously bad segment on this for example).

The problem is that those suggesting this aren't really engaging with how our finance system works. What they're saying is "I don't want my money at risk" but what they're proposing is "I don't want to ever be able to get a mortgage". They're saying "I'd be happy with an account that doesn't pay interest" but actually, if this product was offered, you'll likely find people still opt for the interest paying accounts that have risk because they aren't really capable judging that risk.

It's also just quite a difficult thing to imagine happening, can you imagine it - out comes this product from a bank "100% backed, guaranteed not to default, 20bps charge, 0 interest", and let's imagine it really is popular and capital flees to it. You've just caused the single biggest run on the US banking system in history. How do you mechanically actually make this work?
Slightly off topic, but how may I get into your field?
Mountain bikes do not require roads or flat paths; they work fine on trails (hence the name "mountain bike"), which have existed since large animals evolved.

However, mountain bikes arguably require even more technologies than other bicycles, especially for suspension and brakes (MTBs pioneered the use of disc brakes on bicycles).
Aside from aesthetics, I also want to re-case them for better airflow than what's in the laptop body. There can be quite a lot of sustained performance to unlock this way, as laptops thermal-throttle a lot compared to servers and desktops.
The current crop of electric motorcycles are like that.
Cursor is an editor made for programming with AI
Increasing number of researchers ar e now citing papers directly from arxiv instead of some xxx society or xxx university journal.
The issue isn't with CURRENT government.

The issue is that with such huge loopholes, FUTURE one might exploit them on a bigger scale than what happens in Russia.

And being constantly vigilant and opposed to such laws, is what keeps the society sane and working.

The protest in France could be officially banned, but it wouldn't stop the protesters. Whereas current Russia would bring in the army to forcefully stop protests.
> Commercial buildings are contributing up to 40% of all greenhouse emissions

Is this a number you can reliably back?

(The hard 40% part, "up to 40%" includes "only 5%" of course)

At face value it doesn't appear to mesh with, for example:

https://www.epa.gov/ghgemissions/sources-greenhouse-gas-emis...
I use it on Mac but I'm really excited to see how much better it is, as I think its really poor compared to its competitors.
You do understand that proof of reserves is the opposite of what is being claimed right? Ah, ah, the accounting firm that use to do those engagements even stated thus in its refusing to do more of them.

What is required to proof reserves is a full audit instead, which no shady speculator will do which is in fact what all these 'exchanges' are which also means your crypto is at full loss category if you are using them.
Twitter is the first implementation of write-only memory.
also: https://youtu.be/USKD3vPD6ZA
It’s not that there is no insider trading, it’s that there are government regulators investigating and prosecuting violators.

Just for example the amount of wash trading in crypto is substantial, and if done on stocks would be found and prosecuted.
Interesting. I had only heard this in the context of Apple before and not Amazon. There is a clip from a Steve Jobs video describing how you need to work backwards from the end user experience and then figure out the technology
Wolfram Alpha says that the Hay River is way way bigger than the Amazon.

https://en.m.wikipedia.org/wiki/Hay_River_(Canada)
PSA: Are you using minoxidil for treating hair loss? In that case you must not take Aspirine, as it significantly reduces the effectivity of minoxidil.

https://pubmed.ncbi.nlm.nih.gov/30226287/
Lessons from Linguistics: Internationalization Best Practices
> People are buying EVs because they're better

Disclaimer: I am ignoring the environmental implications here.

Arguably they are not from many different POVs.

They are better for car makers, they can market them at any price they like and States all over the globe are subsidizing them, so that people can afford them.

In my Country buying an EV means paying 33% more for the same exact car, but with less autonomy, which is not a great proposition for the majority of the people living here that need a car.

The real solution would be removing cars from the streets as much as we can, which is about 50% of them more or less.

To follow on your analogy: saving car industry by switching to EVs would be like saving horse carriage industry by putting an engine on them in 1920.
Elon Musk and top AI researchers call for pause on ‘giant AI experiments’
Please don't stop the progress and testing in prod. Don't listen to luddite IT folks
Agree 100%. CT is fun if you like abstract mathematics. But it is not a practical useful tool for developing software. A much better choice would be “Software Foundations”. Now that is also hyper abstract math but useful for developing real world software. As demonstrated with the CompCert and seL4 projects. Even pro mathematicians are starting to dive on (see the LEAN mathlib project for example).
The first actually useable OSS LLM will explode in popularity. The public won‘t be censored by big tech‘s idiotic moral ideas.
The Strongest Magnet
So i just found that the "SnowHaze" browser prevents fingerprinting on fingerprint.com and https://browserleaks.com/canvas

• https://apps.apple.com/nl/app/snowhaze/id1121026941?l=en

• https://github.com/snowhaze/SnowHaze-iOS
Use own API keys in this desktop app for ChatGPT
Not sure if there was any such attempt before. Must have been - this app uses your own openAI api keys and doesn't need login. Not a public version, in other words.

BTW, built using chatGPT.
How do you feel about models like GPT-4 using tools like that to RE?
If this sort of prevention didn't work for nuclear weapons it'll not work for anything ever.
I can still remember when EVs were physically impossible, and then when they were possible but worse than ICE for the planet, then when they were only toys for rich playboys and on and on.

So I'm surprised by the headline claiming everyone thinks this is going to be super easy.

The big question is what sets him apart from all the naysayers saying many of the same things that he's apparently never noticed during his in depth investigation of the matter.
I think you're both over-estimating the situation in the US, and under-estimating the situation in China, but you're right: there's a difference.

My point is that _trusting_ news organizations is dumb. None is trustworthy. Whether their coverage is manufactured/absent/biased because it's required by the government, required by the owners, required by the editor, required by the organizational culture, or even a side-effect of their workload, nothing is trustworthy.

I'm not sure there was ever a time that the press could be trusted, but it absolutely cannot be trusted now.
The "barefoot" phenom is a current fashion. And a recurring one. Most of their marketing points---down to radiographs of feet crammed in shoes---go at least as far back as Munson's book on military footwear.

Fashionable shoes have more pointed toe boxes, but a well fitted Oxford doesn't smash the toes into its point. The toes lie naturally, with empty space ahead. The last designers literally build up the toeboxes.

Stand with your feet flat on the floor, barefoot, then lift one one heel as far as you can while pressing the ball into the floor. How much wider do your toes splay, at their maximum?

I'm all for people using tools to try toe running. Rucking, too. I wouldn't toe run in combat boots, and I wouldn't ruck in "zero-drop shoes". I wouldn't do either in a size too small.
“Software Foundations” is IMHO a much more useful choice than CT.
> I find the drive to make it new is a curse on mobile. Many apps have betrayed me (1Password) or threw away best features (WeatherUnderground) or just lost touch (Transit) when they update their products with new features.

I think this is unfortunately a "natural" progression for companies who focus on growth. In the beginning, they are a small team that has limited resources and is forced to focus on what matters.

Once they grow, they start multiplying the team sizes, introducing new levels of management and hires experienced product and tech people. Often for no other reason that they need to grow, and that means more resources.

The new hires have to justify themselves and need to find work to do. Product people have to make visible changes to signal their worth to upper management, while developers invent new problems to solve so that they rewrite the platform to $current_hype and add complexity and unnecessary scaling.
Programmers like their text editors, or rather, IDEs, which are most likely orders of magnitude more powerful and featureful in text-editing, debugging etc capabilities than Cursor, plus they're agumented by plugins.

Cursor would do much better as a plugin for multiple editors/IDEs (IntelliJ, Visual Code, Eclipse...)
Guess when 3d and VR started? When I was in college, i.e. 1990s. Now, how many problems did it solve? Metaverse is just a vanity project that the board of Meta does not have the power to stop, well no they might have the power but not the will given the stacking of that board.

But, give it another year and the board will act.
Last valid Web Archive capture was on August 5th 2011: https://web.archive.org/web/20110805041437/http://home.comca...

"Page created 2003-08-23 and last revised 2005-07-31."

Page also has no sources of its own.
Embedding SQL into GraphQL without sacrificing type safety
> How much is a new Mitsubishi Mirage (for instance) where you are?

Looking at a random local Mitsubishi dealer's website, it looks like a 2023 Mirage is around 19-20k. Which is cheaper than a Bolt, but if you qualify for the full federal rebate or have big state rebates it'd come out about the same price.

They do have a 2017 Mirage listed for $9,900, which is a lot less than the Bolt. The site doesn't say it's used.

> I'm talking about people who can afford a new ICE vehicle, but won't/can't pay the extra to get an EV.

https://en.wikipedia.org/wiki/Boots_theory
You are supposed to annotate what every part of the file is and how you want to display it. It's usually easy to distinguish reasonable assembler code from nonsense instructions interspersed with undecodable islands.

Disassembling all sections just in case they contain code is a common conservative policy for disassemblers: even without malicious payload hiding tricks even definitely never executed sections could contain embedded executable code.
I just withdrew all my funds from Binance and they arrived in 5 minutes. Zero issues so far. I doubt they don't have enough money to cover withdrawals.
Ubuntu was maybe not a good choice to start with. I installed it recently to find that it runs old kernals and old versions of software. i.e. OBS was a few versions behind.
It is not only the customer who suffers damage, but also the seller of legitimate merchandise who is not compensated by Amazon for fraudulent sales. Also, Amazon 100% has a spreadsheet somewhere calculating the share of customers who don't bother claiming fraud compensation.
And Arabian for the place.
Uncertain Simulators Don't Always Simulate Uncertain Agents
That's why it explicitly states "more powerful than GPT-4", not "all LLM".
that would sadly hurt more, I think.

Journals are eager to publish new studies as facts (did you know that eating sugar will make you lose weight???) (ignoring that all those who were studied were pro byciclers burning off 3000 calories a day)

this will just make it worse, because a bit larger amount of bad papers will get publushed
Wouldn't it be -- at least, with the safety of looking from a distance -- be better that she found another company which actively wants her?

I always get suspicious of mass layoffs -- I always think they are not connected to performance but to networking and marketing of your work.
Humans don't have Lidar. They can still drive just fine. Solving self-driving is OBVIOUSLY not about Lidar.
$15 during happy hour, $20 the rest of the time.