skysight-inc/HackerNews huggingface dataset:
This is a very good question. The practical issues with antibiotic resistance may not be that obvious to a layperson because they tend to pop up in the hospital setting as opposed to the clinic setting that most people are familiar with.

The antibiotic bottleneck centers around patients who show up to the hospital with very vague signs of infection (fever, sweats, rigors, lethargy, etc.) and are sick. Like on the verge of going to the ICU sick. Or already in the ICU sick. These people need an effective antibiotic and they need one fast. You don't have the luxury of sending a culture to the lab and waiting for the antibiotic susceptibility profile to come back because that can take multiple days. So you need a toolbelt of "broad spectrum" antibiotics that are highly effective against the dozen or so bacteria that are the most common culprits of serious infection - something that you can use in the critical first 48 hours, while you're still waiting for culture results.

In practice (at least in the US), your selection of broad spectrum antibiotics is limited to vancomycin plus either cefepime or combination piperacillin/tazobactam. That's it. There really aren't very many other antibiotics that are effective against a sufficiently wide range of bacteria. We do have "back up" antibiotics to use if those fail, but these are powerful agents that come with some really nasty side effects, like seizures (for carbapenems) or widespread muscle breakdown (for daptomycin). And they are pretty limited in number too.

If vancomycin, cefepime, or piperacillin/tazobactam resistance starts to become a lot more common before the next generation of antibiotics comes in, we're screwed. And antibiotic development has been stuck in a rut for decades.
Great.... How do you do that inside a 4 hour workshop?
Probably Eric Schmidt can use his connections to prevent the break up, as he is more connected to the DNC party machine.
I guess the interesting and significant difference here is that value of the previous location of aircraft fades fairly quickly. So just setting up a different server and switching to that is an effective solution. The value here is not retained in the data but instead the network that collects the data.
How did you market NoCodeAPI once you had launched it?
Thank you for posting this. This focus on V2G is nuts.

We move huge volumes of our residential portfolio every day just setting EV schedules - enough that our total residential profile peaks at market bottom price hour nearly every day, even in winter with lots of ”dumb” heating load.
>The default now seems to be to ignore any search term it deems irrelevant.

Could be worse, think of YouTube's search: ignores your query if it doesn't belong to the most popular videos on the platform, gives you irrelevant results from entirely unrelated videos with seldom any relation with what you were searching for, and goes as far as listing every few results 3-4 "you might also like" videos that have nothing to do with what you were looking for, at all, and are just whatever is trending (often actual scams usually related to crypto and unmoderated). I have no idea what twisted company culture fosters this sort of product development, but clearly search, what the company had become a synonymous for, has been tarnished beyond recognition.
Currently running a T1 with a 5800X and a 3070 and loving it too, it really is a great little case.
Since when IIT Kharagpur is Tier 2?
Is there any way that this could be how they help with depression - there’s a lot of research now about various good bacteria affecting your mental well being - and we are living in a soup of antibiotics
Depends on the consumer, I'd far rather order in my own time on my phone. You want to pay more to employ someone to serve you then fine.
Alright, so OpenSky and ADSB Hub are the two I've learned about so far in this thread. Very cool.
Watching WFH tech evangelists being sincerely stunned that GloboTechInc fired them over email (gasp) is not just ironic, but should be instructive.

What did you guys think would happen?

That the company who hired you to build a surveillance monopoly on the internet was going to look out for your best interests?

On a long enough timeline, many SWEs will engineer their job out of existence. Those left over will have to compete with the mythical 10x engineer and the latest AGI shitbot that can debug code all day long without ever having to take a bathroom break, or maternity leave.

To those affected: don’t capitulate to, or engage with the pity machine. It’s all cope. Those jobs, that headcount, is never coming back.

Take your skills and go build something you actually have true equity in.

Godspeed code monkey.
You have a typo on the View API Docs button at https://nocodeapi.com/marketplace/youtube/ that leads to https://nocodeapi.com/docs/youotube-api/. I think it's supposed to lead to https://nocodeapi.com/docs/youtube-api/.
All the FAANG CEOs are represented besides Sundar Pichai. I looked it up and his compensation was $2M ($6M with stock). Wild that the Amazon CEO got paid over $200M more than him.
Yes, you can ask the founder "Andrew Gazdecki" or DM me on twitter (@mddanishyusuf) and I'll send you proof :)
I didn't listen to the full podcast, but as someone who has spent much of my work time in the past few years trying to hire -- it seems surprising to hear its not a pipeline problem. I advertised and solicited from as many diverse venues as I could find and still found hardly any qualified applicants. In fairness it wasn't easy to find White or Asian qualified applicants too, but still found disproportionately more.

My biggest fear is that if we try to sweep the pipeline problem under the rug, we're not going to fix it. I do have a potential solution, but I think it's a tough sell...
Who said it was? I'm just saying I don't need a bunch of useless fluff on a resume.
It's because he exploited wealthy people.
I worry that this is just messaging to build towards 'make DEI jobs immune from layoffs'. eg the quotes from comments:
> "Instead, he said companies should consider race, gender and ethnicity when deciding who to let go."
> 'Only software engineering and data science jobs saw larger declines, at 24% and 27%, respectively.' So the "hard" jobs are actually facing larger layoff waves than the DEI jobs.
wasn't he in charge of their NFT product?

This is pretty telling: https://dune.com/cryptuschrist/Coinbase-NFT

$482 worth of volume traded in the last 24 hours. I don't know what their fees are, but if its like OpenSea (2.5%), then they made...$12 yesterday.
It also has a relatively high minimum wage (compared to the US) and high employment tax and lots of pro-employee regulations. Hiring people is very expensive for employers here, even if _average_ salaries are low.

The cost of living is not just related to salary but also energy being 3x more expensive than usual, house prices, food prices going up 30%, Brexit, etc.
I’ve always wondered the same. I’d be completely lost as to what I’m supposed to do in such a situation.
Software engineers like to believe in science fiction.
(Software Engineer): Depends on the problems being solved. Not everything that a business wants me to do is going to be an interesting problem. The ration of interesting to mundane has been good enough to keep me engaged and I'm pretty happy with that.

As long as there's consistent interesting work to do, I can handle some boring tickets here and there.
The idea of activists/politicians having any say in who companies hire disgusts me

But does it disgust you when companies discriminate based on age/gender/sexual orientation/race/disability/religion/etc?

Should corporations be accountable to society in some way, or do we trust them to "do the right thing"?
The reverse, however, could also be true---how did you get all those fireable white females in the first place?
Monthly recurring revenue typically corresponds with cashflow and cashflow pretty much rules the roost when thinking about useful metrics for a business. With sporadic, or unreliable, MRR you're going to have more risk because there's a higher likelihood of having a "down month" where you're forced to use savings or loans to cover expenses.
That the most unique take I've read on this. Any more details or are you just speaking from experience?
Widening chasm births Antarctic iceberg larger than Los Angeles
They replied the statement was not sarcastic and doubled down.
Well, apparently it’s possible to “hold it wrong” then.

I’d argue if you can wipe it (which requires your iCloud account approval), install it as someone else, login with that new iCloud account, then reset it and it suddenly reverts back to the previous owner, something is wrong or very unintuitive.

The problem on Mac it seems is that there are two official ways to do it. One proper way (the “Erase All Content and Settings”) and one other way (the way we did it, boot into recovery and format it, then go through setup with another iCloud account which apparently just temporarily lets another user use the machine). On iPhone there is no user accessible recovery mode so that can’t happen there.
Reminiscent of robotic surgery - it took years for surgical outcomes on these platforms to actually improve on average outcomes over manual surgery, and for individual surgeons, the learning curve was also unfavorable.

Prostate surgery was a leading application for robot surgery because it's challenging to access the prostate and remove cancerous parts while preserving nerve/prostate function. A decade ago I saw a robotic prostate surgeon at a leading (ivy) research university hospital present data showing that although it could achieve superior outcomes (quicker return to urinary continence, faster mean return time of erection), a surgeon needed to perform literally hundreds-to-thousands of robotic surgeries before they could achieve equivalency in outcomes, and then to get to superiority. A surgeon in training could achieve statistically average outcomes via traditional laparoscopic prostate surgery much faster. Mind you, this was literally a decade after the daVinci was approved for this type of surgery (FDA approved in 2001).
Here's a Harvard fluff piece making the same "myth" claim:
https://www.health.harvard.edu/staying-healthy/stop-counting....

And here is a recent peer-reviewed article that summarizes the debate:
Ludwig, D. S., Apovian, C. M., Aronne, L. J., Astrup, A., Cantley, L. C., Ebbeling, C. B., ... & Friedman, M. I. (2022). Competing paradigms of obesity pathogenesis: energy balance versus carbohydrate-insulin models. European journal of clinical nutrition, 76(9), 1209-1221.
What choice do you think people have? At minimum wage pretty much all jobs are like that.
Either that or due to political restrictions preventing more housing being built, land is overvalued.

Any increase in wages is taken by landlords who increase the rent. The competition for a house isn't the next door house, it's not living in the city at all.
The Computer Scientist Who Finds Life Lessons in Games
ProductHunt was big push for my all projects and twitter.

And after that Google SEO, WOM.
Isn't that already illegal to discriminate based on most of those things?
Garbage in, garbage out. I believe "eating less food" causes you to lose weight. If you provide calorie numbers that correlate, I would ask you to demonstrate causation vs correlation, and I don't think you could do that as cleanly as you think across a broad population.

A better system? Not quite sure, but as always: criticism of current failures does not, by rule, have to come paired with suggestions for improvement.
Yet, their number of warehouse employees is still growing like an exponential curve. Compare the number of items shipped per 1,000 warehouse employees in 2012 vs 2022 and no it’s not wildly different.
Nah, it's because he exploited crypto people.
of course it is a library. An embedded database is essentially a library that you add to your application.

That you can build stuff around it, doesn't invalidate the fact that the core of it is a library.
Ok sorry, I think I misinterpret your architecture. I think you mean something like HA with Litestream.
If you're happy with your ORM (and, ahem, your users are happy with your app's speed), then you can disregard this post.

An ORM is an abstraction over what already is a huge abstraction, which is SQL. Therefore it would feel to me like driving a bus by remote control, or something like that.

SQL isn't a procedural language, like C, Fortran, Cobol, Java, JavaScript, Python, Ruby, etc. It is a "query language", I guess, where you tell it what you want, and it decides how it's actually going to find, filter, sort, etc., that data. It's also the only game in town. Is there any widespread alternative to SQL, at least for querying tabular data?

The problem with it being so abstract doesn't rear its head with simple SELECT statements. They all seem to go fast enough. It isn't until you're joining tables together, or no longer getting data row for row but instead aggregating, summing, averaging, etc. Suddenly sometimes the whole thing can slow to a crawl.

Thankfully databases like Postgres let you prepend a command called EXPLAIN to the problematic query, so that you can diagnose the slowness (if you can understand the output of EXPLAIN). But it was a long time before I got good at reading the EXPLAIN output and finding a way to get it to run faster. Even though SQL is so abstract, more just a description of what you want, there is more than one way to write it --- and the difference in speed can be hundreds or thousands of times.

I have had the luxury of working mainly with Postgres for 17 years, and toward the end of it I finally feel supremely confident working directly with it, just using the psql command-line client, and hand-typed SQL in text files, to get exactly what I want, and as fast as I want it (which usually is less than a second). Mind you, I don't work with Big Data, just a variety of CRUD apps but they often have mindbending reports requirements.

It should not have taken me years and years to master SQL (nor should it you). I think the reason is partly distraction, for those of us that are "full-stack developers", and also that there is so little education about how to master SQL. I mean, the books and posts are out there, but the attention to them from the community at large is small.

But SQL is really not harder than the other languages and techniques you know so well. If developers spent as much time on SQL as they do on the ins and outs of React, containerization, CI/CD pipelines, or the quirks of their favorite programming language, I think they would find it easier than most of those things. And it pays rich dividends, because SQL is cross-platform, you can carry that knowledge with you from job to job for the rest of your life, and your inefficient database queries are making your app use quadruple the hardware and 10 times the latency than if you truly mastered SQL.
Thanks. I didn’t know which repo to link to since there is one for C# and one for rust.
The Discord link on ADSBExchange points to a server called "Airframes.io Enthusiasts" - going to the website shows:

> Airframes is an aircraft-related aggregation service that receives ACARS, VDL, HFDL, and SATCOM data from volunteers around the world.

> It is under very active development and you will notice changes from day to day. Also, issues are expected.

> Contributing your feed allows us to make ground developing new decoders and make important statistical observations. It also benefits users of the service so that they can see more about flights as they traverse covered territories.

Perhaps the original founders' work will continue here?

EDIT: It does not seem like the original founders has collaborated with the community on this, and the people there are just as lost as anyone else.
It seems like it’s a library you’re meant to embed in an application and that sqld is just one application built on libSQL.

It does seem like it makes more sense to call it something that alludes that it’s postgres
Anecdotally I've pushed chatGPT pretty hard to give me novel stuff and have found it really hard to do. Sometimes it even gets "grumpy" at me about pushing it.
Proof of Innocence Built on Tornado Cash
https://www.theblock.co/post/204544/tornado-cash-proof-of-in...
Fwiw I would trust a person who has gone through teen pregnancy to understand what kind problems it has. Just like people who didn't get to go to good schools establish scholarships. In isolation, those are the people who will understand the issue much more.
there is only 1 rational course of action:
(1) export and delete your lastpass account
(2) import to new PW manager, in my case bitwarden
(3) change all your passwords
Always surprising to me how many peoples’ moral framework is essentially the Code of Hammurabi with a few layers of indirection.
From the SQLite homepage:

"SQLite is a C-language library that implements a small, fast, self-contained, high-reliability, full-featured, SQL database engine."

Wouldn't a fork also be a library?
I don't disagree with anything of what you say really.

But I think perhaps that "event sourcing is pretty complex" may be due to programming languages and ORM having the object-oriented mindset as the "default" usage pattern. If we had 30 years of tooling evolution and education exposure for event sourcing I do not think it would be "complex".

(Also I mean event sourcing as in "how does one model data in the SQL database", not whether one is doing event-driven architectures with distribtion, async, event brokers etc -- that IS adding a lot of complexity but is something else..)
Yes. I could not tell whether I was enabling or disabling cookies. I don't know whether that was badly done, or a dark pattern.
I'm interested in helping as well (software engineer). This is such a loss for the community. Like other's have stated, ADS-B exchange didn't have to follow the privacy requests as they didn't aggregate FAA data so it remained open. I'm wondering what the future will hold with the new ownership.
Sure! A bit more detail in this thread: https://twitter.com/bensyverson/status/1494532671623544840
That did cross my mind! But what makes Omar different is that he understood his place in the world and was honest about it. Both with himself and with the world: https://www.youtube.com/watch?v=P3i36ybA8Ms
This is beyond impressive, considering you are still young. Clearly, you've skills to reuse rinse and repeat formula.
Why don’t we assume his investors make decisions in their own self interest and that you probably aren’t the right arbiter of what they’d be better off doing?
GP carefully said "package," not salary. Package includes stock compensation.
Decoupling input bindings from game systems with C++/SDL
It actually started to look like real missions ala halo and cod, you had to go activate a computer, place a bomb on fuel tank, kill a specific person. A few missions can probably be topologically morphed into some doom level, but the difference is the missions looked more like an actual "spy mission," like you are actually James Bond, going on missions.

Today, yes it doesn't look like that because it's blocky 3d meshes compared to literally any game today that isn't "retro"-styled, but for the time it was amazing. I don't know if playing it today will be as amazing for you as it would be playing cod or half-life, but for the time it was amazing and influenced a lot that would follow. Also, it's still pretty damn hard even today if you're not a speedrunner[0].

[0] I tried a run through the 00-agent missions a few months ago and gave up, I sort of realized why 9 year old me never actually finished them and only finished it on the agent mode (easy).
If I were to formalize my colloquial understanding of the phrase "ripped off" it would be something like: a transaction took place between two parties where upon evaluation of the results of the transaction after-the-fact revealed that the overall expectations were not met by one party and had the offended party known fully how the transaction was going to play out, the either would not have entered into it or would have only entered into it for a drastically different amount of money.

This morning, I went to a bakery and ordered a blueberry muffin. It was fresh and moist and delicious. I was satisfied. If it had instead cost the same money but been dry and crumbly and had a taste of old socks, I would have considered myself to have been "ripped off". But I put no thought into the transaction, I had a wide range of acceptable outcomes, and I did almost no due diligence beforehand to ensure I was going to get the expected result.

So now, you ask:

> Why does having a contract eliminate the possibility of getting ripped off?

If transactions exist along an possibility-for-ripoff spectrum from "ordering a blueberry muffin for breakfast" to "hiring a C-level exec for X years for $YYY,YYY,YYY", then the closer you get to the latter transaction, the more specific the contract should be about expectations.

Every step along the way to having a signed contract normally involves an increased awareness of expectations by both parties. That's what the contract is. And the moment of signing a contract is an intentional decision to move forward with the transaction as specified. It's certainly possible to subvert the normal process in such a way that you obfuscate your intentions, but even then, the results of your intentions must show up in the contract language itself, or they won't count. Unless someone is holding a gun to your head, or you're not intellectually capable of entering a contractual relationship, the moment of signing your name to a contract is a moment where you are affirming that you aren't being "ripped off", that you've considered the terms and are willingly agreeing to abide by them.

Perhaps it's still possible to do all that and consider yourself to have been ripped off. And perhaps your examples are good examples of such cases. But if your board or C-level executives sign a contract for employment of a high-level executive which includes a 9-figure deal for compensation and they don't have more awareness than a poor person going to a car lot, they didn't get "ripped off", they're ripping off the investors or shareholders by collecting whatever salary they're collecting.

IANAL, also not a C-level exec, also not particularly smart about how crypto "works", but this all seems like fairly obvious stuff.
"Embracing of conspiracy" is not what I mean. You are using newspeak definition for conspiracy. QAnon bites on "conspiracy theories" (that's what you mean) but does not run an international operation infiltrating foreign governments. Communism was/is an international conspiracy to change regimes in other countries.

Show me how QAnon is equal to Marx in universities, academics, and actual politics. Show me Putin's allegiance to MAGA. Show me QAnon has the wherewithal to compose a foreign legion, topple governments, etc. MAGA and QAnon is kitsch.

All your comparisons are nothing and you exaggerate. You're one of those people who believes Jan 6 was a serious threat? So you are r3tarded. Go pray 140 seconds for the "injured security guards" of Jan 6 lol.
I still think of Master Chief's power armor
yes, but "android founder." What great product innovation did this guy pioneer at CB? Any justification at all for a $100M payday?
You're making very aggressive assumptions about amount of use the EV battery would be subject to, to the point of this being a straw man. You're right that people wouldn't agree to have their expensive EV battery trashed by multiple 0-100% discharge cycles daily. You wouldn't get any takers if that was your offer.

A more reasonable expectation is that people would lease a portion of their capacity. Say 20% for argument sake. You could even place other limits on it "never below 50% and above 90% on weekdays". In this example the power company gets to use between 50% and 90% state of charge in your battery on weekdays and pays you a small fee or other compensation in return.