skysight-inc/HackerNews huggingface dataset:
I have a genetic mutation called MTHFR C677T, which means my body doesn't process vitamin B9 with the necessary efficiency. B9 is upstream of regulating the quantities of monoamine neurotransmitters the brain synthesizes (serotonin, dopamine, and norepinepherine).

(Not everyone with an MTHFR mutation experiences symptoms. For a long time I didn't. Best guess is my body changed after a period of intense stress.)

I take L-Methylfolate 15mg, which bypasses my digestion and provides my body with the processed materials directly.

The brand name for this is Deplin, which requires a prescription. I just switched to over-the-counter L-Methylfolate - it remains to be seen if it's as effective.

Fun fact: once I started taking Deplin, I had to come off of all my traditional antidepressants. They were at max dosage and having no effect, but once my brain was flooded with neurotransmitters, all the antidepressant side effects kicked in, including (perversely) amplifying depression symptoms.
Yes this is definitely very useful and essential for "learners" -- to see the correct association visually
Why would you need to do this? It's not like creating tables with columns is a time consuming endeavour
I migrated from lastpass to 1password just a year ago. Could not be happier with their service.
If someone posts something to TikTok, it's available within the TikTok app--but also via Chrome or Safari or Firefox, because every TikTok is available via an HTTPS URL. So yes, it can certainly be linked to on Facebook or anywhere else.

The key issue here is that uploading an audio file to Apple Podcasts Subscriptions makes it available within the Apple Podcasts app--but nowhere else. Not Chrome nor Safari nor Firefox, not Overcast nor Google Podcasts nor any other client. So no, these things are not the same, not even close.

Every podcast ever can be listened to in any podcast client ever, with two exceptions: Spotify's on-demand audio shows that they insist on calling "podcasts," and Apple's on-demand audio shows that they call "Apple Podcast Subscriptions." They are the outliers, and deserve to be shamed for it.

Other solutions for subscriber-only and paid podcast subscriptions exist, but Spotify and Apple are doing their own proprietary things which should not then be called podcasts.
The Fediverse will solve society’s loneliness crisis. LOL
This isn't a refutation. You aren't saying women would trade places with men. You're saying women would trade the current experience of massive attention for a new experience of curated sincere attention. So damaging the male experience further.
I wanted to explain layers really bad, Sam Ruby even put comments in there about it, but I stayed away from it for the sake of more clearly explaining how Linux was configured for Rails apps.

It is really weird looking at Dockerfiles for the first time seeing all of the `&% \` bash commands chained together.
Give phone to child to entertain them - come home to find out they have somehow turned the oven on hours ago.

OT- give a two year old child a device and watch them crash it just by jabbing their finger at it.
> The social dynamic exists independent of dating apps which monetize and exploit it.

> The dynamic is the same in real life...

While I agree it isn't unique to OLD, it's vastly different to real life. In real life you can strike up a conversation with someone, become friends, develop feelings, and end up in a relationship weeks/months/years down the line.
one thing I'd like to see in Django is something similar to InertiaJS [1], just being able to use VueJS for the view layer is amazing and passing data from the backend to the frontend without having to build complex api systems is a godsend. Maybe I haven't done enough research but is there something similar in Django world ?

[1] https://inertiajs.com/
Large Pharma and Life science companies generate huge amounts of documentation around change. They have a huge historical corpus of categorized structured documents that have been reviewed and approved. The quality should be good. Can definitely see a draft document using AI option in the future.
There is an interesting article comparing sex and income inequality:

https://www.overcomingbias.com/2018/06/comparing-income-sex-...

Also a good quote:

“It's a fact...that in societies like ours sex truly represents a second system of differentiation, completely independent of money; and as a system of differentiation it functions just as mercilessly. The effects of these two systems are, furthermore, strictly equivalent. Just like unrestrained economic liberalism, and for similar reasons, sexual liberalism produces phenomena of absolute pauperization . Some men make love every day; others five or six times in their life, or never. Some make love with dozens of women; others with none. It's what's known as 'the law of the market'...Economic liberalism is an extension of the domain of the struggle, its extension to all ages and all classes of society. Sexual liberalism is likewise an extension of the domain of the struggle, its extension to all ages and all classes of society.”

― Michel Houellebecq, Extension du domaine de la lutte
Great write-up. SD's removing the ability to imitate styles will probably go a long way to quell objections, though it will be interesting to see if there's a future legal split over the styles of living and dead artists. I don't imagine that anyone would object to 'autoseurat' for example.

I can see see a future dispute arising over outpainting (beginning with an existing copyrighted work) but there infringement and identity of the infringer (the user, not the toolmaker) is more clear.
Hi Greg,

I would love to hear about the problem space you are exploring. Here is my linkedin: priyankaja
At that point it is an endpoint not a relay.
For an MVP I'm building, I'm using retool as the frontend, Flask hosted on appengine as the backend, cloud functions for async task execution, and a managed CloudSql postgres instance for the data layer.

I suck at UI/UX design and don't want to write a bunch of JS for async webapp stuff, so retool is a force multiplier there and would highly recommend. I Don't want to manage any infra, so appengine handles that for me. After getting everything setup with terraform in a day or so, I spend all of my time developing core functionality and 0 time managing servers or getting a UI to do what I want it to do.

Total cost to host is < $100
It's not a good idea to construe every inequality as an injustice begging to be rectified. In this case as if every person was entitled to a fair share of sexual experience - but people's genitals aren't a commons, thank you very much.
> Cambridge Analytica was actually a violation of FB.

Of their terms of service, less so the actual law.
Poor people, must be soul crushing to have a well-paid, 9-5 job with technologies that don't have an eternal carrot on a stick that prevents them from achieving mastery at their trade.

Where is the excitement of working during the weekend to make sure the dozens of random libraries npm downloaded as dependencies of the one you need to display a neon outline in the list of products are compliant?
That law doesn’t exist. Why would such a law exist?
In a cruel paradox, I find talking to women who are already in a relationship much more enjoyable. They are more humble, open-minded and treat me as a real person, not means to an end or some necessary evil. Which boosts confidence a lot.

Maybe 30 y.o. single women are so for a reason.
Are you a lawyer who deals with traffic law, or is California just some sort of dystopia where you get hundreds of parking tickets as a normal way of life?

Up here in Ontario I've had 1 ticket in my life. I just... no, there is no way you're getting hundreds as an individual.
> training the bottom quartile of men in the basics ....

I always thought schools should teach children "how to date". I went through sex-ed in Delaware public schools in the mid 1990s, and it was all the clinical physical aspects of sex, and the dangers of HIV. There was nothing about intimacy or consent.

I did have a separate class in 7th grade called Conflict Resolution. It felt like a low effort attempt to teach basic social skills that should have been a regular part of schooling since kindergarten.
There was an article a few years ago saying that in Manhattan women outnumber men, and that led to men needing to compete less there, so yeah probably economics related.

But a gov-sponsored app? No way. It's bad enough they have your whole financial/employment history (IRS), but to add your health (medicare/aid) and now dating/sexual histories too? What's left that you can keep private? Sorry, bad idea there.
That’s a LONG time (in total) for employees to wait for liquidity. Yes, they likely provided some opportunities for early employees to liquidate some of their holdings, but it’s got to suck to sit on that much funny money for so long.
This is the correct answer. It's quite shocking how many Django and Laravel answers there are in this thread. Performance and type safety appear to be completely irrelevant to HN.

You should take a look at Vite (https://vitejs.dev/) for a Vue development environment, if you haven't already.
And this is all in the context of layoff sprees happening at mostly U.S. based tech multinationals. It’s not as if Booking.com has been doing layoffs- though it seems like they already did that a year ago. And certainly Spotify also laid people off.
It's pretty much what OpenBSD is doing at bootup.

Truthfully though you're right, using typical linkers, this would be pretty slow; at least a few seconds for large binaries, to minutes for things as large as web browsers. However, for many binaries, linking can be done much faster; mold claims to be only 50% the runtime of using `cp` on the object files, which is fast enough to even re-link Firefox on-the-fly without it being unusable.

You could imagine writing a linker specifically for this case, that encodes information about the object files directly into the resulting bundle.
I like how the website puts a progress bar at the top to compensate for browsers increasingly hiding the regular scroll bar on the right.
And I guess you could say that nobody deserves to live in an safe environment free of violence, black people don't serve to not get beaten up by the cops, poor people don't deserve health care, nobody is owed a job in a non-toxic environment that doesn't kill them because of stress, etc.

So often when people have problems that are hard to solve the answer is just "talk to the hand" at best.
I worked for a Company that was a vendor for Lenovo. They had some sort of "News about Lenovo" app on all of their commercial grade machines. The content and translations were managed in our system and each computer would pull down the feed from our servers. It was decent traffic, but nothing crazy... Until they made a change and all of the sudden every machine was pulling every hour at zero minutes and zero seconds. We had one minute of DDoS every day at noon for about a week until that was mitigated.
comments here are a great example of the hn bubble. killing youtube, instagram or facebook would be a massive net negative for society right now. the amount of money and people that depend on these platforms far outweigh the concerns of people complaining against corporate censorship.
So strange. It's failure modes are kind of random

black farts - just generates squiggles 90% of the time https://i.imgur.com/znk9lj5.png

red farts - works all the time https://i.imgur.com/KeL5DtF.png

brown farts - works all the time https://i.imgur.com/IwwgQNM.png
Yeah everyone seems to be very focused on sex whereas to me the problem is not fostering intimate connections in the first place. We don’t have an epidemic of relationships that aren’t having sex, we’re having an epidemic of people who aren’t fostering those relationships and as a downstream byproduct they aren’t having sex. Pay a prostitute is a bandaid patch on the downstream problem, but it will never makeup for the loneliness hole of the upstream problem
Dairy is one of the most substantive protein-rich calorie-food there is, right up there with meat and eggs.

For active people and those trying to gain weight, it's a godsend.
A good use case for using HEAD instead of GET
Rage bait, karma farming and creative writing exercises all rolled into one!
You can have a financially dependent relationship with actual love and affection, prostitution is purely transactional. I agree that monogamy as it is usually practiced has some drawbacks and is not well suited to many aspects of modern society, but it does work well for a large number of people, even if it is a minority.
That's exactly what I do - I build a monolith using the self-contained deployment feature and zip it up to the server to run.

The management of certificates, configuration, etc. is built directly into any product I work on. Outsourcing this stuff to IIS, et. al. is exactly how you wind up hating all of this tech in the first place.

Prerequisites are zero if you do this right. I can take a blank EC2 server, copy the binaries over and run them immediately. I don't even have to install any runtimes or SDKs.
Anecdotally agree, I tend to think of SF as a special case due to the extreme gender imbalance and the general sprawled out nature of the bay area
While rare, I have seen it happen.
A family owned financial services company's recruiter made sure I knew the company had never had layoffs to try and entice me to accept a position.
Have I got news for you about the disproportional partner accumulation situation preindustrial revolution..
I'm not sure how its harder than python + django, node.js or php.. I used to deploy with capistrano, then we moved to deploy it from a single rpm file, now we just use or pipeline to prepare pods and push it to k8s, continuous deployment, direct from the gitlab pipeline.. not sure how can it be easier than that.
UK also, in addition to sibling's list.
Nothing really beats Rails. Use something like Jumpstart (jumpstartrails.com) and Avo (https://avohq.io) and you scaffold a full consumer-ready app in literally a few hours.

The thing that bugs me the most with Next.JS and the whole JAMStack movement is that, yeah, you get from "git clone" to deployed on Vercel in two minutes, but if you need to create real app features like a sturdy admin, accounts, authorization, proper asset management, CI/CD, it takes a whole lotta time. I'm not even touching the most common app features.
I'm speaking from experience, from building a Next.JS app for about a year.

Most Next apps out there are incomplete with the worst freaking user experience. Insert any other JS framework or hosting provider in the place of Next.JS and Vercel.

Of course, this is a generalisation, not all Next apps are that bad.

Using Rails is like a cheat-code in dev term.
That sounds like some pretty high standards then. What within the area of tech would you classify as revolutionary then? I'm guessing DARPA: The Internet, IBM/Microsoft: the PC, Apple: the iPhone. Anything else?

I'm talking about the next category of innovation down, whatever you want to call it if you feel "revolutionary" needs to be reserved for generation-defining technologies. Because with your current definition, the vast majority of even large tech companies will never have a product that meets it.
It's interesting to me. I have female friends in their 30s who go on tons of dates but reject pretty much all of them for any long-term relationship. The ones they seem to be in to tend to reject them after a couple of dates.

I'm not there in those interactions but I wonder how much of it is a mismatch between what you desire in a relationship and who you are attracted to in a person.
Second and third order effects.

If the main cause of poverty is unaffordable housing and low wages and poverty is one of the leading causes of depression then the people who have the ability to tackle the housing crisis and low wages but instead choose to do nothing are also responsible for the causation of a lot of depression. The people who are able to do something about the housing crisis are politicians. I do agree with you though if you think political media is pretty toxic.
It's interesting that there is so much technology and third party business involved in the process of moving value.

- Visa has a market cap of $463B

- Mastercard $362B

- PayPal $90B

- Block $48B

Could it theoretically all be automated?
have plenty of cash reserves. cash in a bank account, and low expenses are the way to weather these moments.
I think so too. 9 times out of 10 a person has horrible eating, sleeping, or drug habits and a sedentary lifestyle.
The best description I heard about Docker was from a fella I worked with a while back who said, "Docker is terrible, but it's less worse than Puppet, etc." after another co-worker challenged our decision to move forward with Docker in our production infrastructure.
> Women have 2x the rates of depression as men. But is there any reason to think that 200 years ago it was even more so?

That's interesting. I would have thought men would have it more since it's an abnormality, and with only 1 X chromosome, men are much more frequently abnormal.

When I said "If the state of women's rights around the world returned to where it was 200 years ago," I meant if women who currently had normal human rights lost them. In that case we would see a major increase in depression among women, the point being that depression would be explained much more clearly by genetic factors, even though the genes didn't change; the interaction between the genes and the world changed.

> I think we overestimate the impact of external factors on our internal mental states.

We definitely do. And the external factors that affect our happiness the most are often the least controllable.
Looks extremely cool, but I wish this was a web app. I can't use it because I don't have an iOS device and I also think it would be useful on desktop, to take a break, as an alternative to checking HN, twitter ...
Excellent summary :)
1. k8s 2-node cluster on cheapest instances

2. Hosted Postgresql

3. Hosted Graphql API layer microservice (like hasura)

4. Hosted hhtps server

5. Some kind of cloud storage solution

5. Load-balancer ingress

6. Some kind of CDN

Spinnable in less than day with SSL on, works perfectly for any app to scale and covers most production problems
> Wow - so what does 2022 look like?

Hasn't been reported yet, but some simple extrapolation would expect top 20% to drop to 8 lifetime partners and top 5% to increase to 80 lifetime partners.
"She thinks I'm exaggerating ..."

Probably best to keep it that way.
Shades of Cyrano de Bergerac. This is a flirtbot!

Maybe somebody else already had the idea: the DNS for cyrano.ai is aleady taken.
"Mostly local" might need to be better defined here. I routinely do a 200mi round trip two times a week with no other commuting otherwise. The implication might be that EVs can't do long distance, but that wouldn't be true.

EVs come with other conveniences too like lower maintenance demands and costs. As with all things, there are just tradeoffs. I would also expect the software to be better in non-traditional manufacturers' cars - though this is not EV specific.

But... you should absolutely have a place to charge that isn't a Supercharger (or other fast charger). I think it's crazy people buy Teslas and go to the Supercharger every other day for ~30 minutes+.
I hope the depth of that analogy is intentional.
Interesting insight from Darwinism point of view!

If we have solved the public health problems, does it make Monogamy an empty construct? Or there are other social/economical/biological factors that hold it in place?
/sarcasm

Well government likes equal outcomes. Perhaps a new department to ensure everyone is getting the same results regardless of gender, attractiveness, hygiene, etc.
IBM would do these layoffs regardless. The whole "everyone else is doing it" is just convenient timing. IBM has lots of dead areas / legacy software & typically those areas are the ones hit hardest.
> I'm ok looking and I feel like I can make women like me. I still struggle sometimes. Many of my friends do much worse than me. I have friends that I find intellectually stimulating, average-looking, that have not been touched by a woman in years.

While I think that globally the sentiment about this is true (market is driven by women), I also had many average-looking, intellectually stimulating male friends that said "that girl is too ugly".
And because things are bad we should go ahead and make them worse?
A crawler should be limited by the network not CPU. Outside of the language making it easier to handle multiple concurrent connections, I doubt speed would be much of a consideration.
You can bootstrap the compiler. It's a chore but not impossible. More usefully, you can check that your builds are identical to other people's, so at least your compiler isn't uniquely compromised.
I've never been much a fan of Node for backends though. There's no framework that's as feature packed as, for example, Laravel on PHP. And you have to worry about leaking state/memory across requests.
Thanks for sharing and i'm happy to be your friend :)
You have unlocked the power(utility?) of excel for sooo many people! Msft should buy this from you
An asteroid the size of a delivery truck is expected to pass about 2000 miles from earth on Thursday night. It was only discovered last Saturday.
As someone who has not yet adopted to Docker, even though that seems to be what is done on contemporary best-in-class PaaS....

I don't totally understand the maintenance story. On heroku with buildpacks, I don't need to worry about OS-level security patches, patches to anything that was included in the base stack provided by the PaaS, they are responsible for. Which I consider part of the value proposition.

When I switch to using "Docker" containers to specify my environment to the PaaS... if there is a security patch to the OS that I loaded in one of my layers... it's up to me to notice and update my container? Or what? How is this actually handled in practice?

(And I agree with someone else in this thread that this fly.io series of essays on docker is _great_, it's helping me understand docker better whether or not I use fly.io!)
None of these frameworks (next.js, remix, redwood, etc, etc, etc) is a even half close to what you need for any non-trivial MVP backend. Such as:

- Validations

- Translations/localization

- Error and request logging and auditing

- Security (CQRS, CORS, CSRF)

- Permissions and a way to integrate it with your authentication (does supabase handle this? don't know)

- Email sending

- Background jobs

- Caching

- File uploading

- Rate limiting

Several of these very important things are missing for all of these frameworks. While most of them come by default or with community maintained "de facto" solutions.

I'm yet to see a feature wise equivalent framework in the JS world to laravel/django/rails. They're batteries included or full stack just on the surface, as soon as you start using them you start missing a ton of stuff.
Ever since Obamacare banned discrimination for pre-existing conditions, health insurance is entirely a function of money. If you're taking home significantly more money, you can set a small fraction of it aside to cover an employer insurance gap.

The problem for programmers is not cost of insurance, the problem is weird long-tail shit like insurance denying treatments you need, or wildly over-billing you.
That's the point... it's an MVP, they went for an easy basic case like Parking Tickets.
It grew them by orders of magnitude and in some cases saved them from failure outright.
A friend of mine did a small experiment. She’s quite good looking so she made a new account and another guy friend made another account at the same time. She has usually has 3000+ likes on bumble so we wanted to see how many she gets in 30 minutes. In 30 minutes the guy got 5 because of a new account and she got 150.

The ratio is so badly skewed that the apps end up working for no one. Neither men nor women.
Kilobyte = kB.