I agree that the cholesterol factor seems pretty well debunked, but I think the mistake originally appeared because dietary cholesterol is typically present with saturated and trans fats. These are known to typically function as a lever for blood lipid levels. If you eat them, your blood lipids will temporarily rise and gradually fall. The fact that this doesn’t become chronic for you seems abnormal (but great), and I spend so much time trying to understand it better. Very intelligent people are on both sides of this thing, saying blood lipids aren’t the issue or that they’re the core issue.

As you mentioned, eating whole, healthily prepared eggs and meat makes a difference. If you were getting that much egg and beef from McDonald’s you would likely be buried in the ground by now.

I used to eat like you and my blood work was horrifying, though. I’d say I was eating around 95% whole foods by volume, though I had a weakness for rice noodles and fermented sausages. I stopped that diet though and now my blood work is excellent, too.

This is a contentious but super interesting thing. There are some factors here I suspect matter a lot, but haven’t been properly proven out yet. I do think in the next decade or two we will start to get a good grasp on it.

One is gut flora and enzyme production. Essentially, where is that food broken down and what’s present as it happens? This is a big science experiment with significant variance across individuals. One common variable that’s becoming very obvious though is that people who adopt “western diets” tend to lose a staggering amount of gut flora diversity. I think this matters a lot for anecdotal but also research-oriented reasons.

I had a chronic bacterial illness which required nuclear-grade antibiotic regimens and that completely crushed me. I was burping up the most putrid gases, getting awful cramps, and having bizarre GI motility issues for over a year after; I’d never had troubles with food in my life. I’ve wondered often if I’d done my blood work before that, when I didn’t feel like garbage eating that food, if it might have looked good like yours. I really wish I started doing blood work sooner. Regardless, I wonder if gut flora can protect us from the harms that the greater body of evidence implies high amounts of saturated and trans fats can cause.

I’m totally plant-based now, and I meet countless people who say “I can’t eat like that because I just feel like shit all the time”. And I think yeah, I did too. I had to do all kinds of stuff to build my guts back up and now I’m a plant crushing machine. Had I eaten like this when I ate a lot of meat, I’d be bloated and miserable all the time. There’s no way I could handle so much fiber and sheer bulk. What your flora and system is accustomed to seems crucial to both what you’re able to eat, what you want to eat, and how well it supports your health.

As for enzymes, we know various foods stimulate enzyme production and in their absence that enzyme will reduce or even vanish — sometimes permanently. What you eat with your eggs and steak, whether it’s with the meal or 12 hours later, very well could protect you from what harms others. This kind of thing is researched and there’s growing evidence for its importance, but it isn’t clear who/when/what happens since nutrition is so incredibly diverse. I can’t wait until we understand protective mechanisms (enzymes or otherwise) better. I suppose the best known is antioxidants, but there must be so many more.

Finally, there’s the genetic factor question. We know there are hyper responders to saturated and trans fats. Are there hypo responders? I haven’t read up on that. If so, the greater body of evidence would indicate that most people are not hypo responders at all, and that saturated fat intake (animal or plant) can easily become excessive and harmful.

All of this is to say that I doubt there’s a one size fits all in any case, but since saturated fat appears to become harmful in most populations, I think people should be careful and if it’s an option, so regular blood work. I’m also not aiming to be contentious or argumentative; I find this stuff interesting as hell and love to discuss it (and learn things — I’m by no means an expert and I don’t have all the data).