skysight-inc/HackerNews huggingface dataset:
The COVID vaccines were rolled out on the basis that they were more-or-less safe and probably efficacious. A lot of them turned out not to be as safe as anticipated - eg, the blood clotting issue in the Astra-Zeneca virus or the myocarditis issues in the Moderna vaccine that have gotten its use limited in Scandinavian countries [0]. It turns out that the evidence that was collected at speed wasn't actually enough to justify the actions taken.

That was a good standard and an appropriate thing to do. But that standard is lower than what the medical regulators usually accept. As you point out, Phase 3 trials are good to do but it is going to make it a lot harder to get a vaccine to market if people have to take them seriously. Vaccine makers should be allowed to sell vaccines that are merely safe and effective; they shouldn't have to pass a higher standard than that to sell the things with a disclaimer label.

As an aside I'd also question the efficacy results as the vaccines are probably a lot less effective now. It appears the virus has mutated quite substantially. But that hasn't changed the vaccine approval status, raising interesting questions around why efficacy is even a requirement to sell the thing. Why not just a safety study with the requirement that efficacy data will be collected and made available? We need to figure out if something is efficacious, but there will be more money to do that - and better data - if it is allowed to go to market. As we can see from COVID, jabs in arms and money are the two things missing to make vaccine development fast. The normal regulatory framework makes both those things hard to get.

> If you want more vaccines, tell some of these multi-jillionaires to quit fucking around with virtual crap like Bitcoin and Twitter

Didn't most of the wealthy people in Bitcoin make their money in Bitcoin? There weren't a lot of ultra-wealthy people putting serious money behind it as I recall.

[0] https://www.reuters.com/world/europe/finland-pauses-use-mode...
You’ve still got time to learn a little bit about half a dozen things, if you’re so inclined.
That is the underlying tone that comes across to me whenever these subjects come up. Effectively pushing against the idea makes one a "racist" or a "white supremacist" as far as I can tell. I don't know how to respond to that kind of labeling because I don't find myself disliking people because of something as superficial as their skin color.
The lack of proper 27-inch displays with the quality of Apple (apart the $1800 Apple Display) is the reason I’m not replacing my iMac…
You're so silly. Everyone else was reasonable in response or directionally correct. Lol

Yeah, more gold is mined in general, but the rate of which is tiny, and the cost of which is way too high.

Of course if we achieve multiplanetary whatever then gold may become worth less, but not worthless.

Still, that's why BTC may be better, buy then what's better? Digital of physical sarcity.

There's a lot of depth and nuance that humans don't have perspective enough to really weigh in on yet here so...
I bombed my AP tests after a year of stress, what a waste of time and a consequential amount of money at the time

Whereas the community college classes I also took in high school were like 8 weeks long, and - like the rest of college - you really only needed to do the midterm and the final and you get the same credit

AP test score transfers credit across the country while being unnecessarily stressful and long courses. community college credits cannot be guaranteed to transfer and have more utility locally or in an adjacent school system, while being shorter semester long courses. Dollar costs are adjacent.
They have to spike unemployment to lower wage pressures, thats it.

The Fed has to do this because they vastly overstimulated. It was entirely avoidable if responsible policy had been pursued

The people who make it into a bleeding heart kind of issue are largely misguided, and don’t understand the distinction between real and nominal. Real wages have been declining at the fastest pace in history yet they point to nominal numbers like its some victory
Salmon. Not raw fish.

Proper source: https://www.npr.org/2015/09/18/441530790/how-the-desperate-n...

TL:DR "Traditionally Japanese do not eat salmon sushi and it was invented in the 80's by the Norwegians to to try to sell more of their over abundance of Salmon."

See also: https://news.ycombinator.com/item?id=31148527
Yes, the passage of time is a side effect. If your functional program is measuring the passage of time, it must accept time-elapsing arguments which are independent of its computation. If its own computation’s elapsed time is part of the computation, that’s inherently impure. That’s okay, but it’s a limit of functional programming purity. If you’re not measuring the function’s own passage of time but rather time passing as a concept, you can just pass arguments to the function which satisfy that interface and test how it’ll behave. That’s what’s awesome about FP: time is a parameter to your function like any other, and you can call it with any equivalent thing.
I've been waiting for a cinematic version of that for ever!
Tokyo is a cheaper place to live than most people think -- in fact, it is probably cheaper than any major city in California. But most people in California would not be willing to sacrifice the standard of living they have, even in apartments. Many studio apartments in America are quite a lot larger and better equipped than a one or two-bedroom apartment in Tokyo.
The purpose of Twitter threads isn't to have conversations, it's to wage cultural war. Very different goals!
I made a pact with a group of friends never to bring up Monty Hall again, especially not when alcohol is involved.

The only things I’ve seen people get more upset about than MHP is infidelity and politics.
It's less about the algorithm, but more how gpg/pgp is constructed/used. No forward secrecy, leaks info, bad text authentication, and other. Those things maybe can be fixed, but they're not.

https://latacora.micro.blog/2019/07/16/the-pgp-problem.html

Edit: an alternative for file encryption is age, fast simple and secure. Signing is signify.
There are a couple (…um yeah…) of things different between Moon and Mars: lunar day is about 2 weeks long, which basically rules out solar-only colonies and lack of any sort of atmosphere makes radiation a significantly worse problem (not that it isn’t one on Mars…)
We haven't done so because it does not benefit us.

Establishing a self-sufficient city on Mars does benefit us, even if it is more difficult.
Previous discussion of NPR article covering the 1980s push by Norway to get Japanese people to accept salmon: https://news.ycombinator.com/item?id=10243823
> certain cultural and demographic factors...considered a bit taboo to mention

I doubt that these factors (presumably the more heterogenous racial and cultural makeup of Japan as compared to the US) have anything to do with the contrasts for operating small businesses that are specifically mentioned in TFA:

- For any two-story rowhouse in Tokyo, the owner can by right operate a bar, a restaurant, a boutique, a small workshop on the ground floor — even in the most residential zoned sections of the city.

- Liquor licenses are extremely cheap and easy. A liquor license in an American city can sometimes run up to $500,000.

- (In the US) Usually for retirement, people are counting on their property values going up so they have a strong incentive to resist changes that might threaten them. A lot of the dynamism we see in the emergent urbanism of Tokyo are things that reduce predictability, which reduce property values.

Are there cases in the US where similar liberal regulations for operating businesses have been established, and shown to fail due to demographic or cultural factors? I suspect not.

But as things stand now even in small US cities, there is a ton of red tape that stands in the way of small businesses. That has little to nothing to do with cultural and demographic factors; and happens to be largely the focus of the article.
Ether is a productive asset, you can get cash-flows through staking.

You can also get access to debt and pay it. Aave, MakerDAO, Alchemyx...
>is OK to be expensive.

That is until you run the calculation when the cost of doing it are in the tens of thousands per unit. Suddenly it doesn't make much sense.
They are currently net food exporters, but with catastrophic harvest failures that would probably change. I'm not sure if anyone has run a detailed analysis taking all the factors in to account, but I wouldn't be so quick to assume they would "be fine".
Doctors make the worst patients.
Isn't the earth's eccentricity incredibly low? (To the point that human-noticeability or non-precision-machinability are out of the question?)

That's not to say I have any comment on the accuracy of ellipse calculation. Keplerian mechanics are beyond me. But I did see a the gear-ratio calculation repo linked: https://github.com/amandaghassaei/tellurion-orrery/tree/main...

It seems angular positional error after 100 years of simulation was the optimization goal.
I would recommend using signify. That's what security researchers also recommend. Simple and elegant tool, designed to only signing, unlike gpg which is used for encrypting and signing as well.
Shows picture of "Entrance to underground cavern on Pavonis Mons" then states "The goal of this essay is to persuade you that we shouldn’t send human beings to Mars ..". Your failing pretty hard so far.
I have a Macbook Pro but keep it plugged in for longer stretches of work. I couldn’t give up the convenience of being able to just unplug and sit on a couch from time to time. Not mentioning working from places outside of office and home.
Human progress is the act of changing the environment to suit our needs.

Flippantly using "stop destroying our environment" brings to mind a pastoralism that was triumphant in the 90s but is basically unworkable.

Your suggestion requires degrowth, and degrowth would entail a humanitarian disaster of epic proportions
In Poland, steak tartare (raw ground beef with raw egg yolk, onion, fermented cucumber, pickled mushrooms, salt and pepper) has always been massively popular.

In the 90s and 00s, raw yolk was optional due to "popularity" of salmonella. Raw beef meat was somehow still acceptable.
Exactly. The root cause of NIMBYism is not preservation of property values. It is preservation of neighborhood character -- low density, peace and quiet, low traffic, etc.

People who just spent hundreds of thousands of dollars for a down payment on a house in the suburbs do not want their neighborhood to change into something that is not a suburb. If they wanted to live in a dense urban area, they would have done that.

As housing gets more expensive, this tendency will only increase -- if you had to work really hard for a really long time to buy a house, you will probably be more unhappy to find out that your neighborhood is changing than if you didn't have to try that hard to get into it -- especially when your options to move elsewhere are at least as expensive.
I went to a university in South Africa which had the opposite problem, grade deflation. The engineering school was masochistic in its obsession with lowering grades and failing students. Despite working extremely hard I went from 90%s to 60%s. But I was considered lucky because most students failed (and by most I mean +90% of the class) and repeated years. I did not. The lecturers repeatedly blamed the students but if even A students are failing I think it's not the students fault, it's the school's.

My university teamed up with an American University, Embray-Riddle, to offer a joint masters. Embray-Riddle required a minimum average grade of 80%; my university came back to them and said no one in the last 10 years qualified for the masters. Eventually they lowered the requirements just so they could have students.

Later I did my masters in the Netherlands. The university made me do extra courses to compensate for my low grades. But I ended up doing reasonably well with an 8/10 average and was the top student in a few subjects.

Grade inflation sounds bad but I can positively say that grade deflation is worse. It badly demotivates students and robs them of years of their life as they repeat courses.
You’re mistaken.

Rate of CPI change is declining on a MoM basis due to one time fiscal headwinds/supply normalization. The demand side has not been addressed at all, with nominal GDP growth close to 10% YoY and the tightest labor market in history along very high wage growth numbers.

If the Fed doesn’t raise unemployment before loosening policy, CPI will rebound due to the level of labor market tightness and wage growth.

It’s possible the Fed will use declining headline CPI to justify pivoting prior to rise in unemployment, but this will almost certainly turn out to be a mistake and require even higher rates a year or two out.

If the Fed pivots before actually triggering a solid softening in the economy, all assets will rally and labor market will retighten.

They made exactly this mistake many times in the 70s and 80s. The only way out at this point is to keep policy tight until a recession event kicks off
Why is CI Development so bad?
Anyone else have these headaches when doing CI development work?
How does this compare to hurl.dev?
And yet you should avoid farmed salmon[0].

[0] https://en.wikipedia.org/wiki/Aquaculture_of_salmonids#Issue...
I don't think that's true. What is the alleged treaty called? The Antarctic Treaty binds the contracting states to prohibit individuals from doing various things in Antarctica, the Outer Space Treaty doesn't really do that, and arguably does the opposite by prohibiting territorial claims. Regardless, I don't think any treaty should be taken very seriously. They will both be violated whenever it's expedient to violate them.
> There is a size limit for standard libraries?

There is a size limit to what language curators are able to maintain, yes.

The idea of the standard library is that it will select components that are general enough to cover a wide range of use cases; therefore the language builders ned time to review every new proposal, and their time is limited.

You may dump everything under the sun in the standard library, but then it won't be better than what you get from a library marketplace.
> What evidence do we have for this?

If you use the site you can literally see new changes daily, not all of them are great but at least it's not a stagnated mess like before.
Use a flagship smartphone on a professional Italy-designed stand and look for a pro app owned by Big Tech? I'd start looking at Google's Pixel 7 based on what one respectable online reviewer has said about the camera.
> ...a literal Venereal disease...

No, that would still be figurative.

The entire mars thing is discredited with NASA budgets and criticism of US government programs, then the criticism is taken as a given, the idea called a cult, and then and only then is private endeavor, the thing thats actually going to go to mars, even brought up. If anything the arguments are good ones, against bureaucracy.

When private endeavor is addressed, of course Musk is mentioned. Then all his marketing hype is mentioned, he's chocked up as a charlatan, the one thing conveniently, conspicuously left out being the fact that SpaceX has delivered on everything it has set out to do so far. Talk about hand wavy.

The entire article is interspersed with unfunny jokes designed to make sure you don't think too much about what you just read. It's a weak "this is a dumb idea" argument after another that does a very good job of hiding the fact that it has almost no arguments of substance. It basically amounts to "we don't know how to recycle shit in a closed loop, the money could be used to send robots, we don't want to contaminate mars with coronavurus" (I can play the lame joke at the end of every important sentence game too).

You don't think people should go to mars? Too bad. People are going to go.
I have spent large parts of my life living with and interacting with people who are not my "skin color" so, yes, not a problem at all.
> (1) Stop destroying our own environment, duh.

I agree except this doesn’t seem possible neither politically nor economically… launching people to Mars really sound easier
Adults created the school environment and place the kids in it, and perpetuate it, and all knowingly.

I don't think you can separate adults from the awfulness of school, including the awfulness of kids toward kids, because school isn't a Lord of the Flies situation where the setting happened by itself, and the ongoing proceedings happen without witness and active maintainance.

Ask any teacher or admin and they may say "this system has problems", but tomorrow everyone gets up and does all the same stuff, so we are a full participant in this.

Me too, even as someone who never had kids. I'm complicit in the sense that even though I went through the process and know how awful it is, now that I'm past that, I'm relieved that this problem and those people (kids) are all kept on some kind of reservation out of my hair. It's really somewhat like packing undesirables away in a compound.

Even though I don't have kids, I don't think it would be wrong or unfair to still expect me to have some sort of share in a general collective responsibility (beyond simple taxes) to help raise (and deal with) the young. After all I was one once and could have used a better society, and I still have an interest in it since they are still part of the world I have to inhabit, and are people I will have to deal with.

Please don't "If you feel a calling then go work at a school". My point isn't about me or any individual, it's that we all have this vested interest and this responsibility, we've just set things up in such a way that most of us can shirk it without having to face up to that's the essense of what we've done.
> then throwing better students at them would result at more As

Also, the Flynn effect: "the substantial and long-sustained increase in both fluid and crystallized intelligence test scores that were measured in many parts of the world over the 20th century" - https://en.wikipedia.org/wiki/Flynn_effect

> A researcher who'd give current Harvard graduates some of the older questions could find out if the toughness of the exams went up, down, or stayed.

I strongly suspect this wouldn't be informative. The base knowledge of what we expect students to know has shifted.

Some might be topical: "How did Harding conduct his campaign?" "Name the primary components of a steam locomotive."

100 years ago I believe there was still an expectation that students knew Latin. The 1869 Harvard entrance exam at https://graphics8.nytimes.com/packages/pdf/education/harvard... has two pages of Latin and two of Greek.

(Most of the student then would have come from an upper-class prep school, where they would have a training that let them be able to answer "Bound the basin of the Po, of the Mississippi, of the St. Lawrence." and "Supply the two names left blank in the following passage from the Oration for the Manilian Law.")

Consider how calculus is now regularly taught in high school, while pre-war high school ended with solid geometry.

Or, consider how an English literature course 100 years ago (and its tests) would have focused on the literature of England and the US, while the equivalent modern English literature course would likely have drawn from the much larger Anglo-sphere.
This page specifically suggests using salmon for sashimi, and doesn't present the idea as particularly novel: https://archive.org/details/encyclopediaoffi0000mccl/page/26...
I would put it in orbit around the Moon. There’s not much on the Moon, other than regolith at the bottom of a relatively shallow gravity well I guess. If you expect the Moon to be a stopover in space tourism, don’t make the people go down the gravity well, that’s a waste of energy for everyone who wants to visit it.

We could treat the Moon as a particularly large asteroid-mining process, don’t live on it, just extract resources.

I don’t think there’s much point in learning to live on all these different rocks. Most of space is space, we should focus on learning to live in space.
I think bullies usually “learn” it somewhere - like being bullied themselves or outright abuse. Or they’re just budding psychopaths. (Which occur at 1/100 rate of the population-and I really wish this was considered more seriously.)
Paul Graham wrote an essay about this: http://www.paulgraham.com/identity.html

Though he primarily talked about religion and politics (it's an old essay), I see people attaching other concepts to their identity, and then verbally fighting to the death if you point out the slightest flaw in any of these concepts.
The market of VFX, which without an Mac Pro, might end up going back to Windows or custom built Linux desktops, like many Hollywood studios did when migrating away from SGI, and Pro wasn't still an option.
Yeah, I was going to mention 27 inch iMac as well. I used to work for a design agency and we used to buy 27 inch iMacs with upgraded CPUs and 16GB of RAM, and then we would install another 32GB of RAM ourselves. The quality of the 5K screen was good enough, savings on the RAM upgrade were significant, they were quite good computers for the price. We used them for all designers that didn't need to attend too many meetings. More senior people got laptops. During COVID we moved everyone to laptops, but I was still curious what Apple will do with the powerful iMac. Let's not forget they also offered iMac Pro, with a Xeon CPU and 128GB of RAM.
The cost to orbit is, err, astronomical.

I'm sure that when Starship craters the cost per kilogram to Earth orbit (following it making some literal craters in development) we will be doing just that.
Nxp sells a PCF2131 with an internal TCXO that runs on 64 nanoamps when not doing anything else. So with a modern CMOS process, the TCXO itself is not a big deal. A clock pin at 32768 cyc/s looks to be way more power hungry, which tells us that an ideal low-power solution is an all-in-one SoC.
So perhaps he is personally communist but his policies are social democratic? I'm not communist but I do agree with the part about inheritance tax to combat wealth accumulating more and more wealth and power. It just doesn't work that well because of the wealth power thing going on there.
I enjoyed high school (because I wasn't bullied, had friends and was doing well).

I was bullied in primary school and hated it. I still did well grades-wise.

If you weren't bullied seriously you probably can't understand how big of a deal it is for small kids. Like psychological-issues-30-years-later serious.
Rails bullet gem is here to solve the N+1 query problem. Let's create this problem first, and solve it thanks to the Rails bullet gem.
> there's nowhere to test that kind of pressure differential on Earth

This is patently false. NASA has a 100 x 120 foot cross section vacuum chamber at Plum Brook.
The Martian atmosphere provides almost no protection against the heavy ion component of galactic cosmic radiation, which is the dangerous stuff. The Moon more than makes up for its lack of atmosphere by being deeper inside the Sun's magnetic field than Mars.
There’s some very interesting speculation on the ArsTechnica forums about how expandable RAM on a Mac Pro might look. It’s not my speculation but it’s definitely not all said and done from what I’ve read.
Bullying doesn't usually happen in plain site of teachers, administrators, or parents. Often it's only noticed after a students mood changes, and it can only be dealt with when that student is willing to share what is wrong. It's also not easy to spot right away when you're seeing 100 kids a day across 4 or 5 classes.
I still have yet to use my crypto on crime, i have however bought numerous things with various coins..