skysight-inc/HackerNews huggingface dataset:
David Humbird's 2021 paper "Scale-up economics for cultured meat"[1] is a pretty damning study of the problems with lab-grown meat. His core conclusion: "Capital- and operating-cost analyses of conceptual cell-mass production facilities indicate economics that would likely preclude the affordability of their products as food."

Does anyone know if the problems that Humbird describes have somehow been solved?

[1] https://onlinelibrary.wiley.com/doi/10.1002/bit.27848
The article says:

> Some hope that lab-grown meat could reduce the carbon footprint of the food industry.

Some hope. What are the facts?

I am sceptical that a lab process can be more efficient than a biological process. And being less efficient would it not use more energy, resources, and release more carbon?

The energy for biological processes is often largely solar, for lab processes often largely from fossil fuels.

I have no data, does anyone?
Ah, that makes sense! Thank you!

I’m much less skeptical now
Maybe some folks will enjoy this as a food product.

It's not clear to me that there's a real upside to this though, for folks who don't mind killing and eating birds.

Research I have seen (you can see it too: [1]) indicates that chicken, dairy, and legumes are all about as low-impact as it gets when it comes to protein sources for humans.

As other folks have mentioned, scaling up the meat lab causes a lot of headaches because the lab meat doesn't come with its own immune system the way a chicken or a cow does. Headaches in the form of increased operating costs and energy inputs.

[1]https://link.springer.com/article/10.1007/s11367-015-0931-6
It did! Particularly because "affect" is the word for the whole phrase "effect change in", and so the whole phrase would be required in order to properly substitute, and so without the whole phrase the meaning is...affected, because the original report from monotype used "affect".

See https://www.monotype.com/neurons "Can fonts really affect our feelings?"
In a world where the animal’s well being is valued more then the economic output of the producer this might be true. However in our current economic system the economic incentive favors taking as much blood as possible without killing the animal while providing minimal relieve.

I have no faith in a regulatory framework being enacted and enforce which will minimize this suffering while keeping businesses profitable.
> This looks good, but this is an outdoor weather station. OP is asking for an indoor air quality monitory.

I replied with an indoor no-DIY suggestion and code at top level: https://news.ycombinator.com/item?id=33774695

> I actually wrote a book on this topic earlier this year. It walks you though setting up a weather station...

... and replied to this from immediately above with a similarly no-DIY weather option.
We also hired some Agile consultants, but a couple of months ago. Unfortunately, it took our C-suite only 3 months to abandon the path of the samurai, erhm, I meant: the path to Agility.

1. The experience

The experience with the consultants was really eye-opening. I will try to describe it below.

Since day one, without having much understanding of how and why we are organized, the consultants started seeing problems, and, oh what coincidence, they had the solutions for every-single-thing that they noticed. They tried to convince us, in no particular order, that our problems were:

- Not following Scrum well enough. That continued until we asked for specifics what part of Scrum we are not following well enough. Surprisingly, they didn't have a ready answer for that and then dropped it.

- Not following SAFE. Scaled Agile For the Enterprise sounded good to our C Suite, but the consultants played themselves by saying they can help us implement it. Our management, just like a gazelle seeing an encroaching predator, avoided the trap.

- Not having Agile coaches on a fulltime payroll. Guess who is an agile coach that can work fulltime for us? That was easy to see through, our C Suite will turn their nose at anything that implies spending more money, so they were naturally immune to that approach.

- Some Miyagi-Do level stuff about communicating better which was a bit fuzzy to me. I guess the Agile coaches have to...communicate better? One can think of that experience as a lesson, and that by communicating badly, surely on purpose, the agile coaches showed us the value of good communication! That is some black-belt level stuff!

2. Cracks begin to show

Things started souring in the 3-rd month, when our management started getting impatient seeing any results in performance. Occupying all your engineering teams for days each week surprisingly had the opposite effect on performance that our C-level hoped for. Then management also got wind of the agile coaches' vision of a "perfect Agile company". According to them, to be Agile (capitalization intentional), each of our teams needed to have:

- A Product Owner

- A Scrum Master (a dedicated person who ONLY does Scrum Master-ing)

- Agile Coach

- Team Lead (responsible for developers' growth)

- Tech Lead (responsible for tech decisions)

- Developers, if the budget allows

While we had only POs and Developers, with rotating Scrum Master role, with one developer being the Tech/Team lead. The prospect of having to hire more people to fill all these Agile roles spooked our C suite to such extent so they completely abandoned the whole Agile idea and let go of the coaches. And just like that, Agility was not spoken about since.

3. The results

Three months later, thousands of $$$ and people spending their time in meetings, the results can speak for themselves:

- we have spent thousands of $$$

- people spent their time in meetings

Based on what you wrote, I think you will see similar exciting results! Onward to Agility!
This visualisation was an eye opener. https://justone.earth/food/

Perhaps an individual animal suffering is less compared to a wild death, but the sheer volume has to count for something.
How would you know next time you order a steak at your favorite restaurant? I can see restaurants substituting - just like they do with fish.
In terms of veganism. Some will, some won't. It depends. Some vegans will be against any suffering and might consider the harvesting of cells from the progenitor animal. Others may be against this due to a lack of consent (from the animal). Others might consider the initial harvesting as harmless, e.g. the cells/DNA might have naturally shed. There's quite a spectrum of vegans out there.
I visited Nepal a few years back and it was amusing seeing the UN drive these massive shiny land cruisers while everybody else was drying cars a bit smaller than a 90s civic. Optics matter, and maybe a Hilux or RAV4 would have suited the environment better
But more privacy mean less data they get and less revenue they generate by using that data, similar to how Meta/Google are affected by Apple privacy changes, at least that's my speculation
Attackers bypass Coinbase and MetaMask 2FA via TeamViewer, fake support chat
Wikipedia also deletes articles about female academics who go on to win the Nobel prize the next day. I don't particularly care about the "consensus" that they build.
Good pun, I appreciated it.
But it’s almost certain they don’t use the clay soil in the greenhouses, right?

You almost always grow in soilless medium or hydroponics in greenhouses.
Three things:

1. A Lisp that makes some improvements on Common Lisp in a few areas without losing its essential nature, including its comprehensive support for livecoding.

2. An OS designed for ubiquitous computing and strong individual ownership of data and computing environment.

3. A livecoding environment designed for interactively building 3D worlds.

I've previously been paid to work on things like all of these before, and of all the things I've worked on, they're the ones I would most like to keep working on. I therefore still spend spare time on them now.

Ideally, I would work on all three, and build them all to work together.
Yes. That's the point of the comment.
Examples of necessary things. If the wisdom teeth are coming in straight, they can stay (although most dentists will remove them anyway), but they usually come in at an angle, and need to come out so that they don't cause problems. I agree with you that dentists overdo this one, but for many people it is actually necessary.

In the US, we have 3 kinds of schools:

* Public/state schools: The school is run by a state government. Some of these have good quality, but some are not good. All of them give a huge discount to students from the local state.

* Private for-profit: These usually all suck, and are scams. ITT tech, University of Phoenix, and others are in this boat. These make their money by providing an education for less money than they charge in tuition.

* Private non-profit: The school is organized and run as a non-profit institution, but is not connected to the government. Harvard, MIT, Stanford, and most other top colleges are private non-profits. Outside the US, I think Oxford and Cambridge are also like this. Private non-profit trade schools also exist, and they are usually the best ones. An example I can think of is the North Bennet Street School (again in Boston, MA). The high-end schools in this category tend to get more of their money from donations and endowments than from tuition.
Google says Google should do a better job of patching Android phones
Thanks for mentioning this. I had looked at these before, but was holing off due to the cloud-polling home assistant integration.
Carolina Reaper should be Schedule I then? /sarcasm
Sounds like that underlines the OP's point. Toyota makes more profit in the US on a Tacoma designed for US tastes and price points. The US demand for Hiluxes isn't enough to either persuade Toyota to add it to their US line or importers to pay the import tariff.
Is the Fortuner available in your market? That is how Toyota offers a reasonably priced modern alternative in some countries
A great deal of product is sold daily that exceeds legal minimums. You've seen "organic" or "pasture raised" labels. All of those are driven by the market.
Under sink filter != reverse-osmosis
I've been using DBeaver (https://dbeaver.io/) and I think it's pretty good
>1. Trust hasn't been eroded (i.e. fraudsters/salesmen do not predominate)

I have become much more guarded and cynical in the past few years after a handful of interactions like this. At a bar or restaurant, and strike up a conversation with someone, only to have them, 15-30 minutes later, introduce me to their MLM, FX, Trading Mentor, House Flipping, etc. scam, and then swiftly disengage when I am uninterested.

I'm not a good looking dude, nor am I an extrovert. So I now just assume anyone approaching me in public is trying to scam me.
Some FPGA-based, massively multi-core computing system with tiny cores with bundled memory with network on chip interconnects.

Think tens of thousands to millions on a die (obviously the prototypes would need to be smaller).

I'd like a system that so "flat" in terms of implementation stack that each object is implemented just one or two step above silicon.
They only pay per click, so it may not be wasted money if these "wasted ads" have a low enough click through rate.
Less than $0.34 in volume[1]

1: https://www.microchipdirect.com/product/ATTINY402-SSZT-VAO?p...
I use only F-Droid apps. So I can't use Uber or Lyft.

"It looks like F-Droid does not have any apps matching your search string "Lyft" "
The irony is completely lost to him.
Yes we agree, only not on the "a bit more" cost. The cost is significantly more - even if imported from a much cheaper country. Also the request is huge compared to what sustainable agriculture can sustain - let's not forget that the farmers of yore weren't eating beef with each meal, while nowadays it's a matter of status for many.
I'm kind of missing the part that explains why you'd need this?

I don't think it completely solves it, but it would be useful to be able to apply styling to a specific part of the page ie: highlight something so when you send it, it saves the receiver a little time searching for it.

Or in a similar vein, wouldn't it be cool to make any header an anchor? So I could say,

http://example.com/article.html#second_header

or whatever. Not the same concept, but it would be useful.
Yeah. While the instantaneous power draw is absolutely colossal, the actual energy drained from a battery starting a (healthy!) engine is fairly minimal, and its replaced very quickly by the alternator once it's up and running. Stop/start engines also use the ECU to stop the engine at the right point in the compression cycle for it to fire immediately, without cranking, so there's even less drain. (Even pre-stop/start engines in cars with modern ECUs tend to leave them in a position where they fire almost immediately.)

What kills batteries is deep discharge cycles. Sipping a bit of juice to start an engine and replacing it quickly does almost nothing to reduce its lifespan.
I thought those types of shots were "woah, cool!" when I first saw them. But they got old and overused fast. I'm so glad those days are (mostly) behind us. It's interesting to me how that came and went as a photography "fad" in less than a decade.
Twitter is now having trouble paying some employees on time
Excellent article explaining why lab-grown meat will never scale: https://thecounter.org/lab-grown-cultivated-meat-cost-at-sca...

> David Humbird, the UC Berkeley-trained chemical engineer who spent over two years researching the report, found that the cell-culture process will be plagued by extreme, intractable technical challenges at food scale. In an extensive series of interviews with The Counter, he said it was “hard to find an angle that wasn’t a ludicrous dead end.”

> Humbird likened the process of researching the report to encountering an impenetrable “Wall of No”—his term for the barriers in thermodynamics, cell metabolism, bioreactor design, ingredient costs, facility construction, and other factors that will need to be overcome before cultivated protein can be produced cheaply enough to displace traditional meat.

> “And it’s a fractal no,” he told me. “You see the big no, but every big no is made up of a hundred little nos.”
Because of intensive electricity needs, Agro Care started its own small energy company. The carbon dioxide generated is used as a nutrient for the crop, piped into the greenhouses via huge ventilators, where it is turned into oxygen by the plants. The upshot is 99 percent efficiency and much less carbon dioxide released into the atmosphere.

Many many years ago, I grew a special plant in a secret room under a house that also had an indoor pool. The pool was heated with a natural gas heater. I directed the flow of the the vent pipe into the grow room. The effect it had on growth was nothing short of amazing. I'd see several inches of growth in a day when the heater was going full blast.
> This is, in my opinion, not true in some cases. Sometimes, I'll write unit tests that never fail, and are purely to allow me to verify one of my assumptions about the code. Basically, the unit test is a tool to force me to think through each line of the code, and that's it.

That is fine and has value, but that is usually called an assertion (and most language have them under some sort of assert() function), which is different from an unit test.

> If I add a website uptime monitor (a "foo.com returns 200" type test), should I immediately take my site offline for a while to make sure it fails?

How do you know if it works otherwise ? In fact for that specific exemple, the most naive version of that test actually misses many failure cases as we've seen again and again in the last decade with status page that fail to detect any error
I never heard of Jimmy Kimmel and I don’t know of either of their connection with the Semantic Web.

I do know Paris Hilton is a savvy businesswoman who created her own business empire while cultivating a celebrity image that makes her look dumber than she actually is.
I don't think Intel has even decided whether to fuse them off or not. In my newest Intel desktop, a Core i7-13700K, AVX-512 is actually available. It wasn't available on the i7-12700K that was in the same system on the same motherboard a few weeks ago.
There's a button for that and you have enough karma to use it.

But really I can't decide if links to Twitter are better or worse than links to Medium. 1 time in 20 or so somebody posts a highly intelligent series of tweets that are worth reading, but most of the time a link to twitter points to a poster that doesn't really have anything to say, a bunch of comments that say at best "me too!" and a lot of irrelevant junk. (Almost as bad a link to a "good" discussion on reddit that is spammed up with irrelevant discussions like a porn site where you have the hardest time telling your wife, 'ignore the 15 animated gifs of pistoning action and look at that picture which I think is really hot')
Apple asked video app to censor Covid search terms, Pepe the Frog thumbnails
Thanks for this. These are all real problems. But why is the solution that I change my behaviour?

This is exactly what I'm tired of: Because other people are assholes with big frail egos who do not understand their place in the world... I have to change? No, they have to change.

Putting this on me just glosses over and prolongs the real problem: That a lot of people with frail big egos need to realize they are not all that and come down to earth.
Your project has 65 issues.

Without looking into the details I could assume these are 65 bugs.
How about porting to Highway, that gets you AVX-512, NEON and SVE(2) from a single rewrite :)
Metacomment, the information density and layout of this page is excellent!
eventually shifting public opinion, and growing the subsection of people who "mind killing" seems like a major upside.
(Using made up numbers here)

Lets say that infection #1 puts the risk of outcome A at 40%

Infection #2 puts the risk of outcome A at 60%

Infection #3 puts the risk of outcome A at 70%

Each infection increases the risk of outcome A, but it isn't an increasing rate.

---

This would be very different from

Infection #1 having a risk of outcome A at 10%

Infection #2 having a risk of outcome A at 30%

Infection #3 having a risk of outcome A at 70%

---

The first case that I described matches Figure 5: https://www.nature.com/articles/s41591-022-02051-3/figures/5

Note the difference in the rate of increase between the infections.

Yes, multiple infections increases the risk. However, each subsequent infection has a lower rate of increase of the chance.
Who holds your data on Mastodon
An OSS tool being used to scan Mastodon Android app to see where private data is flowing. More in-depth analysis to follow soon.
You are wildly mistaken if you believe traditional "cow does whatever it wants until slaughter" farming is where the majority[0] of meat comes from in this country (assuming USA).

[0] https://www.sentienceinstitute.org/us-factory-farming-estima...
The GP's statement sounds like a tautology. Is there a substantial difference between "from our point of view" and "as far as we are concerned ... in reality" under the theory of relativity?

Using the mathematics of a physics theory to deny a tautological(?) statement seems to get at the very issue that Sabine is raising in the original article. Alternatively, you're literally arguing that the mathematics of the theory of relativity bears no meaning in reality. (i.e. "The effect you are talking about is an artifact of a particular choice of coordinates and has no physical meaning.") I'm not sure whether your statement is true, but if it is, it seems to prove Sabine's point...
This reasoning falls apart for structs with array members.
The CIA has moles, send them there...;)
How will these languages emit machine code for every variant of GPU/CPU/DSP/Vector/FPGA/whatever architecture they might run on? This isn't as simple as it sounds.
You may be surprised that academics exist in places that don't have 'university' or 'college' in their name. From experience, folks at places like IBM TJ Watson Research Center, AT&T Bell Labs, Xerox Palo Alto Research Center or DEC Western Research Lab considered themselves academics, had academic job descriptions and did the work of academics.
I have some water cooled Xeon Gold (6100 series) chips. Generally they never throttle, unless running a code well known for heavy use of AVX 512.

So despite running many codes that use all cores 100%, using AVX512 is the only way I've seen them throttle.
Also note that Medicare pays 10 cents on the dollar for everything on the chargemaster. Hospitals are priced to make a tiny bit of money on that, so a lab test with $20 of reagents and $10 of lab tech time goes on the chargemaster for about $300. 1 hour of doctor time easily pushes you into the high thousands on the chargemaster.
What's the endgame of a savings account? Are folks just going to sit on their money until it eventually collapses?
Second stage is duplicated but the first stage is still a single point of failure. The backup for that is your buddy.
I’ve only done a half dozen dives, but losing the computer isn’t what I’d call an emergency.

You call the dive and surface slowly. Maybe you don’t do a second dive if you can’t be sure of your limits. It’s an inconvenience.
That is strange and interesting as it seems counter-intuitive since a B.A. in say, physics, is less rigorous than a B.S. from a pure physics/mathematics standpoint.
I have seen projects use Discussions instead for feature requests, and (open) issues for things the maintainers have a pretty solid understanding of things that should be worked on and closed.
Well, what is it that you're measuring? co2? Particle density?

You say that you want the sensor to measure what it says on the tin, but maybe you should start by defining what "air quality" means.

And then maybe you can find some simple one-off components that do all the individual measurements. I for example found a cheap and simple USB connected co2 sensor, that just changes colors based on co2 levels.
I think you mean extrapolation, not integration, but that is unlikely. I do not know whether it has been tested on dogs, but the behavior of human ball catchers can be described by a simpler algorithm.

Extrapolation would compute where and when the ball would land and then move one’s hand towards that location.

A simpler algorithm that we think humans use is to move in such a way that the ball stays in the same location in one’s visual field.

So, if the ball moves up in your visual field, move away from the ball. If it keeps moving up, move faster. If it starts dropping down, slow down. Similarly, if the ball moves left/right/down, move left/right/towards the ball.

If you manage to do that, the ball will eventually hit your eye. For dogs, it then is a small last-ditch change to make the ball land in their mouth instead.

That algorithm never uses the ball’s distance or speed, doesn’t require one to know that gravity accelerates the ball in a particular direction, and doesn’t compute where or when it will be caught.

I think https://psycnet.apa.org/record/1994-36011-001 (paywalled) describes something like that.

For humans catching a ball in one’s hand or kicking a ball, it’s a bit more difficult, but I doubt they do the seemingly necessary extrapolation of the ball’s path plus trigonometry to compute shoulder and elbow angles.
The point is, it’s easy to vomit a laundry list of reason why a company needs more staff. But it doesn’t shed light onto why a 7000 figure is reasonable until it justifies why other figures are too high or too low. Nor does your comment.
In the first example a & b are variables, which can be assigned to each other. In the second a & b are pointers, but b is fixed, so you can not assign a value to it.
I plan on trying to grow some of these flowers next year to see how numbing they are to eat. It looks like they are not had to grow.
https://en.wikipedia.org/wiki/Acmella_oleracea
For some reason this doesn't hold on Raptor Lake, the successor to Alder Lake. AVX-512 works if you disable all the efficiency cores.