skysight-inc/HackerNews huggingface dataset:
Correct.

See for example:

https://journals.asm.org/doi/10.1128/mbio.03617-21

"These data suggest that virtually all individuals with existing anti-SARS-CoV-2 CD8+ T-cell responses should recognize the Omicron VOC and that SARS-CoV-2 has not evolved extensive T-cell escape mutations at this time."

https://www.nature.com/articles/s41423-022-00838-5

"Although the Omicron variant escapes neutralizing antibodies induced by COVID-19 vaccination or natural infection [1,2,3], our current analysis demonstrates that T cell epitopes are considerably conserved in the Omicron variant and that substantial proportions of memory T cells elicited by COVID-19 vaccination or natural infection respond to the Omicron spike. These results indicate that memory T cells may provide protective immunity during reinfection or breakthrough infection with the Omicron variant."

Here's a review of all the SARS-CoV-2 T-cell epitopes:

https://www.sciencedirect.com/science/article/pii/S193131282...

"Here, we focus on a specific topic: our current knowledge concerning the definition and recognition of SARS-CoV-2-derived T cell epitopes in humans. While the data related to this topic was initially sparse, 25 different studies have now been published as of March 15, 2021 [...], which collectively report data from 1,197 human subjects (870 COVID-19 and 327 unexposed controls), leading to the identification of over 1,400 different CD4 (n = 382) and CD8 (n = 1052) T cell epitopes."

And I'd highly recommend this video on the adaptive immune system, along with the whole rest of the series:

https://www.youtube.com/watch?v=dXL2TvhNqZI&list=PLGhmZX2NKi...

(I think that covers how proteins get chopped up by proteases and then those short epitopes are displayed on MHC receptors and undifferentiated T-cells learn to identify them)
When it comes to audio, it didn't help that AKM had a factory go up in flames[1], completely destroying most of it. It seems they've managed to shift production of some popular ADCs and DACs to other manufacturers[2] recently.

As for other chips, part of it is the toilet paper effect. From what I've heard, companies are buying 5x or 10x what they normally buy, just to be sure they got parts for production. Since the situation is still bad, I'm guessing people are still doing it.

Especially ICs are made in batches, so once it runs dry the manufacturer can't just print out another 10k units, they got other stuff lined up. I see for STM32s a lot of stock is expected at the end of this year or first half of next year, which lines up with what their CEO said that things will start stabilizing at the start of next year.

I'm just a hobbyist who knows a few EEs though, so might be wrong. But this is my impression.

[1]: https://www.audioholics.com/news/fire-destroys-akm-audio-chi...

[2]: https://www.strata-gee.com/akm-responds-to-strata-gee-reques...
Bless their hearts, UI Designers. Just remodeled my kitchen and had to actively dodge my designers' and showrooms' recommendations of a "modern" look which is basically all white or make it look like a friggin office morgue. It's not flashy but it is very utility-first and is beautiful.

I aimed for something that _wouldn't_ need to change visually with the times. UI Design is often the exact opposite: showcase that your property is on the bleeding edge of design.

I wonder what they'll do once they realize you can only round a corner so much.
They're reusing the old enclosure so they save on tooling & parts.
It does sound exactly like that. Guy sold a van, but his business codes we completely unrelated to that type of transaction so it got flagged. It wouldn't surprise me if that was a common Stripe issue considering how easy and contact free it is to get started.
There's been at least one incident where I spent hours sitting on a runway after landing. The pilot was professionally, but obviously very agitated. Does the crew not get paid for that time?
Someone has to care enough to notice, often the case.
Well yes. There's a lot less need for dipper changes after 12.
Quite. It's too depressingly plausible a thought as it is, without digging up evidence that it might actually be true too.
But great for the scenario that the person I actually responded to described.
Work is not always about content creation, some people work mostly by consuming content (reading websites, browsing photos, selecting movie clips, navigating PDFs, or something else) and iPad is great for consuming content.
Candu's actually solve most of the problems the PWR constantly lies about. If people were proposing building those (and demonstrating that they weren't even more expensive) I don't see the issue.

They're hardly the super-100%-reliable baseload advertised, or anything approaching 'too cheap to meter' though.
The library works too for a quiet study space you can be at for long hours without paying a dime
No.

The western half of the US has many monoculture forests where forestry companies manage them with thinning, herbicides and selective planting.

Natural forests in the west are diverse and contain many species of trees. They are different trees than you see in the east, and many of the coniferous species appear similar.
Show HN: HacKit, a macOS app for reading Hacker News stories and polls
I wrote a macOS app for reading Hacker News stories and polls and recently released version 3.0 with new features. It is written in Swift and uses AppKit framework.

It is a Mac-first app which is built for the macOS design language. It looks and feels and works like a proper macOS app made with love and care. It is not a port of an iOS nor an iPadOS app nor anything else. I am quite proud of it and I hope you can appreciate it too.

So, I recently updated it to version 3.0 with new features such as tracking stories by marking it as (un)read, (un)favourite and (un)hidden. There is also folder management to organise stories and smart folders that track stories by certain attributes.

It also supports the Touch Bar with customisations.

I would love it, if you could try it out and let me know what you think of it! I welcome feedback and please do let me know if there are any bugs or crashes. I did all the testing myself to the best of my ability.

Oh and about the in-app purchases, it is just the tip jar and it is completely optional. The app and all its features are absolutely free to use.

If you like HacKit, please kindly leave feedback on the App Store. It really helps, no really!

Have a good week!
Darn, wish I learned of this advice 10 years ago.
This is pretty damning, can anyone corroborate or provide a rebuttal?

What's that quote about people conveniently not understanding simple concepts when their livelihood is on the line?
I haven't used BitBucket for years, so I'm not commenting on that specifically - but to me it makes sense that the underdog necessarily forges ahead, because it needs some differentiator to persuade people away from the market leader.
Every human has exactly 1 testicle, or why you can't just take an average and claim that for the group.
Pretty brazen move to steal all the cars of your app users.
Would "Microsoft" be Skype for Business, Microsoft Teams, or both?

We migrated off Skype to Teams. Cisco Webex Teams, that is. :(
>did they in fact obtain the required signoffs,

You don't get official "signoff" when you're at that level. You get plausibly deniable permission with the understanding that the powers that be reserve the right to pull the rug out from under you should doing so be politically expedient.
In a lot of parts of America school funding comes from local taxes so regions would need to band together to provide consistent funding across districts (which would cause the richer districts to lose funding money which pisses off rich people).
I wish there was a post like this about fire.

On atomic level. Like atoms oscilating? How many photons are emitted when say 5 carbon atoms connect with 5 oxyxen particles?
I tried searching and no avail.
Cybersecurity Will Not Thrive in Darkness
Driving is the American way and our cities have always been built around roads, from the very first day that an American landed on the shores. It would actually be un-American to shun cars, as it were.
Now imagine if you didn't live in SF.
I want to feed jellyfish flavoured water (think chicken stock), and then try to cook them. This couldn't be done with wild fishing, but if the jellyfish could be temporarily transferred to a holding tank while alive, it could. The chicken stock would penetrate deep into them due to the nature of their open circulatory system -- allowing the jellyfish to self flavour themselves.
Same here. I guess we are very old.

OTOH, companies like these should hire us Elder Things to check whether they are naming something after something people like.
That's a big if there. There's no guarantee that the US intervenes, especially depending on who the president happens to be at the time.
* Lagrange's objections
I don’t think a single bike advocate starts from the position that “everyone will ride in all seasons from day one!”

The solution to get people riding in summer is the same as winter… safe infrastructure.
Rogobi - https://www.rogobi.com/

Scientists have a big problem. Abstract search can take up a big piece of any researcher's time. They often farm it out.

The quality of results can vary depending on who does it. Researchers in sibling specialties often use different phrases for the same concepts.

Rogobi manages cross-disciplinary search by collecting terms across disciplines and guiding your search as you go.

Like other abstract search engines it also manages PRISMA details, collects and generates result reports for your clients, and coordinates multiple researchers sifting the same results.

The startup's difficulty is finding the sweet spot of a customer with money that also recognizes the pain point (shallow/silo'd searches due to search term fracturing across disciplines).
Yeah I remember the dorm bathrooms on a sunday, full of puke from saturday before the cleaning staff showed up on monday morning.
> I've forgotten my old passcode and its basically bricked as a result.

You can use recovery mode to reset them: https://support.apple.com/en-us/HT212787

Or if that doesn’t work, you can factory-reset them using DFU Restore (google for it). If you don’t have a Mac but a PC, you can use iMazing.
Very probably.
I believe a lot of that "towns are built for cars" has to do with the population density of the surrounding area.

I was using Eau Claire as an example... Eau Claire itself has a population of somewhere between 68,000 and 70,000 depending on when the count was done. 70 is a nice round number. Eau Claire is in Eau Claire County which has a total population of 105,000 (2/3 the population is in the city) an area of 645 square miles (1670 square kilometers) and the population density for the county is 165 people/square mile (64/ square kilometer).

We head to Assen, and that has a population of 68,000 and move up to the province of Drenthe... that has a land area of 2634 square kilometers (1017 square miles), a total population of 493,000 (nearly 5x the population of the county of Eau Claire) and a population density of 188/square kilometer (490/ square mile).

This is, where I believe, things get different when doing these comparisons. The city of Eau Claire needs to be built for the people who aren't in the city (even though most live in the city). Its a 90 minute drive there before you get to Minneapolis or if you head in the other direction, its 90 minutes before you get to Wausau (population 40,000).

In Drenthe, there probably isn't any place where you need are 50 miles from the nearest hardware store or grocery store of reasonable size (according to Google Maps you can drive from one end of the province to the other in under an hour). Assen to Groningen (p. 200,000) is 1/3 the distance of Eau Claire to Minneapolis.

With that much higher of a population density it makes a lot more sense to optimize for more local transportation.

If we took a Voronoi chart based on cities with a population of more than... 40,000 and overlaid that on Wisconsin and the Netherlands I am fairly sure that the area that each city reaches to is larger in Wisconsin and that the population that area is larger - that there's a lot more rural population in Wisconsin.

The consequence of that is that the cities at the centers of each area need to be designed primarily with distance travel in mind rather than local travel.

The places where those areas are smaller because the cities are more closely packed (the large metro areas on the coasts in particular) it is more feasible to invest in local transportation options because that citywide be serving a higher portion of local population rather than the "out of town".

In terms of investment in bicycle infrastructure - it is those places that will have the greatest return - like Portland and Seattle.

Trying to redesign Eau Claire or Wausau for micro mobility means that population outside of the urban area is very poorly served by the city.
In a very simple way: it's basically single remaining option if someone doesn't want to live in Apple dreamland for some reason (there can be multiple from economical to ideological) AND do not want to own "chineese" phone

I'm aware that there are some other brands but they all have issues which not necessarily place them in competitive place vs Samsung, some examples: Motorola (horrible updates policy, even worse than Samsung) Sony (small selection of models, pricey, no idea about updates), Pixel (not available in some countries, bad battery life, quality issues, price)
Yes, Zulip chats and histories can be published and indexed as an opt-in feature.
The linked reddit post is a word for word copy of an earlier reddit post by another user: https://www.reddit.com/r/stripe/comments/wa1zd6/run_from_str...
alternatively: https://archive.ph/8aXik
Getting into Harvard
Who got the top bunk?

I love visiting my family but after a couple weeks, I feel like a kid again and start acting like one. Asking for dinner, sneaking out to smoke, staying up late watching cable TV. Any extended amount of time feels unhealthy.

But now that they're about to start getting actually old, I want to visit constantly because nothing is forever.
This post seems like a rant; I don't particularly like Zig but the criticism here are weak. No http server in the standard library? Well, Rust doesn't have one either. A financial incentive to promote the language? Yes, so does every other language; what language isn't promoted? "XXX in Rust" is a meme on HN. The tweet was pretty mean spirited but has nothing to do with the technical foundations of Zig.
I am a big Netflix fan (subbed since 2003) but I am concerned about their future since 2017 or so. The reality is that streaming is becoming a commodity technology. What was cutting edge in 2007 and new in 2010 just isn't very differentiating any longer. I don't know what their alpha is.

Everyone seems to complain about Netflix content (though I think it has the best selection, but whatever) and I worry they are fighting a front they are unlikely to win. They are a tech company--not a film brand.
I'm allowed to read it and learn from it. To distill the core concepts and recreate it.
To be very clear, I don’t use this, but I confirmed it does work and generates the same codes as the linked article. Requires Bash (3+) and doesn’t work as written in Zsh.

https://gist.github.com/jsjohnst/95f34bc1f6ab46fd5c038138f0e...

————

read -r -p 'Secret Key: ' secret_key; dgst=$(printf '%016X' $(($(date -u '+%s') / ${TOTP_PERIOD_SECONDS:=30})) | xxd -r -p | openssl dgst -sha1 -mac hmac -macopt "hexkey:$(printf $secret_key | tr '[:lower:]' '[:upper:]' | base32 -d | xxd -p)"); offset=$(( 2 * 16#${dgst: -1} )); token=$(( ( 16#${dgst:offset:8} & 0x7fffffff ) % 10**${TOTP_DIGITS:=6} )); printf "%0${TOTP_DIGITS}d\n" "$token"
I'm surprised at how strong the views are about this. I interact with jetbrains primarily through "Shift+Shift" and start typing the action I want. The UI is unnecessarily cluttered, once you get used to using the command palette.
As Devs: “I don’t want to maintain the old version. Don’t force work on me.”

As Users: “I don’t want to upgrade to the new version. Don’t force work on me.”

It’s not hypocritical to want your cake and eat it too. It’s only hypocritical if you think it’s wrong for companies to force people to upgrade and then doing that. Not liking when your parents forced you to eat vegetables and making your kids eat vegetables isn’t hypocrisy.
This is also a reminder of the opposite. For those of us on here, we have less than 25% of our time with our parents left.

I lost my father earlier this year. I count myself lucky that I felt very satisfied and complete in our relationship.
> So I always have to look on these "How synthetic X is going to make the real X obsolete" with a pinch of salt.

From your comment, it seems that the linked article is far more fear-mongering than it is; I gathered a mostly optimistic tone from it.

The final paragraph -

> While some of these capabilities sound a bit scary at first, they will eventually become as mundane as “desaturate”, “Gaussian blur” or any regular image filter, and unlock new creative potential.
The other android devices are even worse, Apple is eating their lunch
https://archive.ph/VDwlk
Fair discourse: I have worked at Google, Credit Karma and now Sivo (YC W21) as a (technical) program and product manager.

I know for a fact that Google doesn’t actually have “Product Owner” as a role in their org chart.

At Google, the separation is:

Product Manager (Vision), which is focused on gathering business needs and driving the Feature Roadmap.

Program Manager (Execution), which focuses on finding ways to unblock delivery of the vision with cross-functional teams, such as getting designs, legal approvals, etc.

I recently experienced a Product Owner for the first time when hiring one at Sivo (YC W21).

It seems like Product Owners exist to accelerate the Roadmap vision into Epics and Stories in solutions like JIRA so product visions are more actionable by engineering.

Similarly, while not a role at Google, I have heard that some MegaCorps will have “project managers” that often report up into Program Managers. This is similar to the product owner and product manager relationship.

Hope that helps!
As an alternative, here's my list of cheap FPGA development boards: https://joelw.id.au/FPGA/CheapFPGADevelopmentBoards . It covers a bunch of other vendors.
You won’t get anymore interviews if you don’t sign it. Make sure to read it, but most are pretty standard and just cover if you are exposed to non-public information that you need to keep it quiet especially if they are public.
You don't want Bing. You want Bengal
> The current systems can turn a normally worded question into a web search, and present the results in a pleasing manner.

Pleasing but not useful. I really miss Google search from 10 years ago. I think things started going downhill when they introduced the instant search feature.
Nowadays it's difficult to find anything. The results are mostly irrelevant and littered with spam and AI written nonsense.
I remember I could go through hundreds of result pages and find useful things on the tail end, now quite often I get one page only and nothing is relevant to my search term.
I have to often use quotation marks etc, but even that stops being helpful - basically more often than not I get no results at all.
> I used Stripe for about a year to run a small cell phone store in Denver
> [...] All of a sudden, we run a charge for $3300 because our primary
> processor in my business was down,

This is the same story as https://news.ycombinator.com/item?id=32261868, even with identical wording. Interesting that it's posted by a different Reddit and HN account.

During the discussion it came out that this cell phone store used their Stripe account to sell a used vehicle[0], which is the sort of unusual activity that makes every regulated financial services company sit up and pay attention. A common risk mitigation is for the payment processor to hold the money in escrow until after the dispute period.

[0] https://news.ycombinator.com/item?id=32264886
Isn’t it crazy how much context changes behavior? I’ve found the same. Hard not to be my high school self when back with those friends.
Xbox GamePass is the only remaining holdover for me.
More reason why veterans need more protection in the USA.
Have you tried walking in the front door of the Whitehouse and asking for or insisting on government assistance?

I certainly hope that you'd get thrown out. It's easier for everyone if you go through the appropriate channels.
> Whereas since the entry bar for creating competitive software is so much lower, many countries can afford to nurture genuinely homegrown products, and have a reasonable expectation that they will be competitive.

I don't think it's that. It's that eg. Kakao has KakaoTalk, a chat app. And chat apps tend towards monopolies and oligopolies because of network effects. The value of the app is less in how good it is, and more in who else uses it.

If you're just buying a music player or an office suite for a common file format, what you use doesn't really matter to anyone else, and their choices to you.

Chat apps, collaboration platforms? Suddenly, who else uses them matters a lot, since it's about the people, not the physical function. And once you get big enough, the network effects turns from a hurdle into a gigantic moat.
Consider how worried people are about Google Chrome's browser market share, and how Google is increasingly able to dictate details of the web unilaterally. The Web is made of standardized protocols, but Google has significant control over it.

Consider the state of email, a standardized protocol, where Gmail is dominant, and anything that can't deliver to Gmail is practically irrelevant, no matter whether it follows the protocol.

Now consider Bluesky. If Twitter supports the AT protocol early, it would be by far the largest implementation, meaning that Twitter practically controls it. It would be like Gmail for email, except there are no other options to begin with. If Twitter does not support AT protocol early, then AT protocol will be irrelevant, and other networks like the ActivityPub Fediverse will continue to outpace it.
True. Amber is not really a colour term that's often used in Dutch; most would actually see amber as a kind of orange.
If you're relying on exceptions to make destructors fallible, you are going to have a very bad time. The protocol of throwing an exception is to destroy all objects in scope, and if doing so causes more exceptions to need to be thrown, you're going to end up either with a hard crash or one of the exceptions being destroyed. If the fallibility of resource deallocation is really important, then RAII isn't a good model to use (I prefer something like a connection.with_transaction([](Transaction &T) -> Result) model myself for this).

Given that fallible destructors aren't an issue, exceptions are only an issue for RAII if constructors can only fail with exceptions. Note that Rust has fallible constructors without exceptions, and C++ could implement that too, though it is definitely less ergonomic than exceptions.
The orientation is just a software problem. No reason Zoom et al can't have an option to crop to the right aspect ratio.
Same, "We knew that C++ was harder to scale and maintain high quality as you build a dev team" this just sounds arbitary and a weak excuse to use rust, C++-20 is as scalable as rust with a very rich ecosystem.
While it may be a true statistic, it seems to dramatically miss the boat. Time spent with a newborn, with an infant, with a four year old, with a ten year old, with a sixteen year old, with a twenty year old are not the same. You can have more interaction, more contentment, more sense of continuity, and more sense of family, in a Thanksgiving weekend spent with your adult child and their family than the entirety of your kid's first year.