skysight-inc/HackerNews huggingface dataset:
I find it hard to imagine anyone relying on an app to determine whether or not a wild mushroom is edible or not. The poisonous mushrooms (particularly the widely distributed and complex Amanita types) have some of the most insidious biological toxins known, in particular alpha-amanitin, which has a really nasty delayed-action effect:

https://en.wikipedia.org/wiki/%CE%91-Amanitin

It's mode of action is so unique (binds RNA polymerase, so destroying liver and kidney protein synthesis and leading to widespread cell death) that it's used in molecular biology labs for the study of protein synthesis.

Maybe some of the more obvious edible types (boletes, chantrelles, some others) are fairly easy to identify, but even there they have stomach-upset causing relatives. Anything even vaguely similar to Amanita should be viewed with caution (there are closely similar edible types, no thanks). A few good books with lots of pictures, close attention to things like spore prints, going with someone with a lot of experience, that's the best introduction.
Metformin alleviates neurocognitive impairment via AMPK/BDNF/PI3K pathway
I'm the founder of WunderGraph (https://wundergraph.com) and I'd like to mention it as an open source alternative as well.

What makes WunderGraph different is the focus on integrations. You can easily integrate internal and 3rd party APIs, and choose your own client. We generate code e.g. using swr, so you can build on top of existing ecosystems.

We're also currently building a cloud version, which uses fly.io machines to be able to scale functions to zero and even run a SQLite database that can "sleep". I'd love to hear people's opinion.

Here's a video of the cloud alpha that'll be launched soon: https://youtu.be/N8DFjh7FjLU
Original title: Metformin alleviates neurocognitive impairment in aging via activation of AMPK/BDNF/PI3K pathway
tldr

- AGPL

- No recommendation system

- Videos don't autoplay

- Videos are not fullscreen and have different aspect ratios

It's quite different from TikTok.
https://archive.ph/URMR2
Gren – A programming language for simple and correct applications
Hi Quentin, thank you for your reply. I was just referring to this comment of yours: https://github.com/meilisearch/MeiliSearch/discussions/870#d.... It is good to hear that Meilisearch cloud is encrypted though. Will definitely keep an eye on Meilisearch for future projects.
Running the Race – A Swiss Voting Story
OpenAPI Generator allows generation of API client libraries from OpenAPI Specs
If by “cynically” you mean “inaccurately.” Lobbying involves making Power Points for staffers and doing their homework for them by drafting proposed legislation.
We are on a path to nuclear war
I've discovered great music in Kansas radio stations.
Threadreader: <https://threadreaderapp.com/thread/1335061382501261312.html>
I will never understand why anyone thinks that chrome is anything more than spyware wearing a browser disguise.
The former President of AT&T Illinois has been charged and may go to prison: https://www.justice.gov/usao-ndil/pr/former-president-att-il...
HTMX is much closer to 2006 web than React.
> That's more straightforward when your API looks like REST/RPC calls rather than "renders html templates to a string".

How so? You're now dealing with two applications (or two parts of an application) that need to understand and access authentication as defined by "the app"

If the same codebase handles auth across the board it's much simpler and more reliable.
For me, this feeling came from trying to stay on top of all the innovation happening out at the edge of problem domains. The thing is, none of those problems at the edges applied to me. I was chasing them for the sake of chasing them.

Once I stopped chasing the outer edge of what everyone else was trying to solve, and instead focused on the problem directly in front of me, the anxiety of being on the technical treadmill went away. When I have a problem to solve, I research it. As the outer edges get figured out, they start forming boring tech. I try to keep things boring when doing research - and avoid running up the treadmill unless necessary.
Silibinin is the active ingredient in milk thistle, a supplement available at almost any health food store. Do doctors not know this or are they just letting people die rather than prescribe an OTC nutraceutical? Or is there some reason it absolutely must be delivered intravenously? That seems unlikely since it is orally bioavailable.

Edit: I found this, which suggests that it should work in theory, but intense vomiting from the poisoning probably makes it not possible to take a large dose orally: http://bayareamushrooms.org/poisonings/silymarin.html
How Apeel Works
public schooling and low-tier education were undoubtably the worst experiences of my life. the criminal behavior (hard drugs, regular violence) and resentment of the teachers are the closest thing to hell I have experienced. you got out lucky.
Computer Mysteries
nah it hasn't been and will likely never be, this study doesn't even quantify the damage even suggesting that it's only important for people already vulnerable to alzheimers
Corporations can’t give money to politicians. It’s illegal.
In my experience, when someone talks about "political ideas that are censored" they mean:

1. Ideas that are directly trying to silence others or obscure empirical reality.

2. Ideas that actually can be said but are marketed as being "censored" or "counter culture" to give weight to a narrative.

3. Vague gestures to some other idea that is supposedly neither 1 or 2 but is unable to provide any evidence

I would love to add a fourth entry but in the same way it's inaccurate to assume this is 1 (Apple's "victory", apparently), it would be equally inaccurate to not categorize your views in 3 until you were able to provide specific evidence.
I have no real comment on the site, but just some awesome coincidence. I'm currently on the west coast in a hotel room watching a Nebraska football game on the television. I pull this site up and it puts me in Smith County, Kansas. I turn on the radio and it pulls up the local AM radio call from Superior Nebraska of the exact same game I'm watching on TV. Awesome.
Agree, cheapest I have seen is $500 USD month, but also didn’t look that hard.

And yes, knew of phantasmagoria, but didn’t realize they had NSFW filters off; tested it, NSFW filters appear to be off.
The nootropics subreddit is probably a decent place to start, it’s mostly students and professionals (often with ADHD) looking to improve performance. But of course, with the help of supplements and drugs
that's very true, it's an extension of HTML as a hypermedia, and you can achieve useful patterns with as few as one or two additional attributes (that are extremely symmetric with "normal" HTML).

a good example is lazy loading:

https://htmx.org/examples/lazy-load/

two plain HTML attributes that give you a nice tool for deferring expensive calculations so that users can get to interactive more quickly with the rest of the page
So if you think that consigning millions to wade in heavy metal polluted ewaste for all time is acceptable lead the way.
Well in this particular instance, their codebase size was reduced 67% and JS dependencies went down from 255 to 9 with TTI cut in half.

I'm not one to always chase the new shiny, but that's interesting enough to explore & I think does bring commercial value.

Last note: HTMX really feels much more like 2006-style web tech in philosophy which is a refreshing counter to all the current js complexity.
> Yet we keep falling for their bullshit. Why?

> Because we deeply want to belong to something more than just ourselves, I think.

I think in most cases it's simpler than that. People go along with this kind of BS because they are afraid of being labeled as racist (and in doing so, ironically perpetuate racism). It's a shortcut that special interest have found so shut down discussion: "you're with us or you're racist (or some other 'phobic'") and people end up going along for the most part
Fun fact: the original App Engine datastore evolved into Firestore (which now powers Snapchat and many others).
You can install an armchair on the roof.
google tracks your incognito tabs just like it tracks normal tabs, without you even visiting google.com
How is my example, street signs, an inconvenience to others or needs dedicated street space? Signs need to be replaced anyway, just add a code at the next replacement.

You're thinking back and white "it's not replacing...". What does that matter? To me what matters is "can we make transport better"

I thought the question was "can we actually make fully autonomous vehicles?" If we have that, the value is pretty obvious.
I appreciate your reply and I believe every word you have said. Thank you for the hard work and thought you and your team have put into your products, and I'm sorry to hear if anyone is casting you as faceless corporate politicians reaching for meaningless goals. I know exactly how that feels.

To be frank with my feedback, I am a person who uses Firebase for a side project. I don't have the mental capacity to watch an ~hour talk for each piece of GCP infra I don't understand. I liked Firebase because I could understand it intuitively through its UX.

I'm sure the GCP features are very helpful and innovative and I'd get a great ROI from the talk if I worked on them for my full-time job. But some weeks, an hour is all I have. I'm an app developer and I would just like to deploy my app please, and have the rest fade into the background, or at least integrate with my existing workflows.

Thanks for all your hard work. I understand if "side project developers" is not the top of your funnel. But I hope you hear my feedback.
From what I’ve seen, DSLs are one of the few products where user benefits almost always outshines customer benefits. This is where, it becomes very difficult to justify and hence almost always stay-away-from-market tails.
I'm not sure I understand the use case for this, but I had a go in the playground

let a = [3]
a = [''] // this works?
a[0].length // but this fails?

Error message is

> expecting possible candidates all failed: candidate array failed: expecting number but got string. candidate object failed: missing field 'length' but got number.
I dunno, I took this advice and ended up rolling my own thing that looked an awful lot like a framework, but wasn’t as good because the framework authors are better at JS than I am.

I’ve landed on Svelte+Typescript lately, and It’s Really Doing It For Me (tm). I think the trick is to find a framework or library that gets you, and just run with it.
There's the fentanyl class and the PMC class, and the two rarely meet
Don't look at it. There's a million new things being invented and ignored every day but for some reason if it touches web dev it 1) gets a thread 2) gets upvoted and 3) you people are near the top of every comment thread.

Whatever led to you posting that you don't care about this rather than just not even noticing it like all the new things you see every single day that don't even penetrate your consciousness. Find and kill that.
A brief story about Parkinson's disease
For those curious, the lethal range is thought to be 5,000--8,000 light years, at least for supernovae GRBs, if directed toward our solar system. (GRBs are directional rather than omnidirectional.)

<https://www.universetoday.com/118140/are-gamma-ray-bursts-da...> (Via Wikipedia: <https://en.wikipedia.org/wiki/Gamma-ray_burst#Rate_of_occurr...>)

The energy released, in a few tens of milliseconds to a few hours, exceeds that of the Sun over its entire 10+ billion year lifespan.

(I'm not sure if neutron star / black hole events might trigger larger emissions lethal at greater ranges.)
> People go along with this kind of BS because they are afraid of being labeled as racist

Do you actually know anyone for whom this is true? Afraid of being labeled racist? If you're not racist that strikes me as a crazy thing to obsess over.
I disagree about separate weights. I don't trust judgement of somebody gullible.

But it's related to the problem of what is trust. E.g. I may trust somebody to create a secure software, but I wouldn't trust her take care of my dog. So at the beginning I thought there should be dimensionality of trust. Currently I think it overly complicates things not to mention the problem of categories. So trust means whatever it means for you and people you trust and specific use cases can perhaps be covered with multiple identities instead.

Since you've spent some time on the problem if you have any other insights/ideas/problems I'd be delighted to hear them.

There's a lot of interesting dynamics. It should influence politics a lot. And at the beginning I thought maybe a crime scene too making it harder to infiltrate gangs, but then I realized that as a criminal I wouldn't dare make a list of my accomplices on a device which can end up in hands of law enforcement.
A GitHub App that uninstalls itself
Just use vanilla html/js/css. For most stuff that's fine. React is good for web applications that require reusable components and have a lot of state to manage, but if you are building a personal site just use vanilla.
Some news related to scam call center arrests:

Oct 4 2022:

On inputs from FBI and Interpol, CBI, police forces search 105 locations to combat cyber crime: https://indianexpress.com/article/india/cbi-operation-target...

31 Aug 2022:

Fake call centre busted in Gurugram, six held for cheating foreign citizens: https://www.tribuneindia.com/news/haryana/fake-call-centre-b...

04 Aug 2022:

Fake call centre: Cyber cell contacts FBI, CBI & ED: https://timesofindia.indiatimes.com/city/dehradun/fake-call-...

30 Dec 2020:

India's CBI helped US sleuths shut down a call centre scam that impersonated Microsoft at times: https://www.businessinsider.in/international/news/us-india-c...

17 Oct 2020:

Call centre fraud: US, CBI bust call centres defrauding elderly Americans: https://www.financialexpress.com/india-news/call-centre-frau...
> I find it strange that this article presumes that you have all the right answers and that there isn't the possibility that you are the one who needs their mind changed. It points out that listening is valuable, but not because there's a possibility that the person you're talking to is in the right, no, you should listen to other people because studies show that listening to other people will manipulate them into seeing things your way.

Perhaps the article is being devious here. It's not easy for people to separate intentions and actions - sometimes an intention can form to rationalise a preceding action (e.g. https://en.wikipedia.org/wiki/Ben_Franklin_effect). Even though your initial intention may be to manipulate by appearing to genuinely listen, you may end up just genuinely listening and rationalising that this was your intent all along. This line of reasoning could trick the most ardent zealots into accidentally genuinely listening to their enemies' point of view.

Relatedly, I think another effective persuasive technique is 'seeding'. If you can engineer a 'non-defensive' conversation with your opponent in which you seed one or two critical thoughts in their mind, although they won't be instantaneously persuaded the seeds can germinate into full persuasion later on. However, this technique requires avoidance of confrontational behaviours that cause your opponent to activate their mental defenses.
How long would you need to be lost before you'd try this advice, personally?

A few hours?
A few days?
A few weeks?
And this is why we can't have nice things. This opinion is wild to me. You do not trust a consumer app with life and death decisions, especially over something where the potential upside is getting to eat a mushroom you found and the potential downside is death. Making more criminals is not the answer.
We are also on a path to aliens
Another invisible problem with embedded-DSLs (like maybe building within Yaml) is the inability to break the host language’s constraint, limiting utility of the desired DSL
Show HN: Carefulwords.com – a little bit more than a thesaurus
sure, that takes care of it once...but now the next time I go to work on that section of code, the else is back where I don't want it.

The issue isn't the lack of a formatter, the issue is that some things should be left to preference rather than strictly enforced.
Ask HN: Do you remember Computer Chronicles?
Was the best show about technology! Watching it now isn't just a trip down memory lane it's also insightful as to what we are still working on that we thought we had nailed then. (VR!)

Oh, and you can still watch it - all for free!

https://archive.org/details/computerchronicles?tab=collection
>But you're not occupying it when you're calling them, in effect, "so-called vaccines".

Can I ask why you're using quotes for something I never said?

Follow up question, why do you suppose this sort of dishonesty is needed to make your point if the truth is on your side?
It is a way to mitigate the variability of wind and solar power. You can heat the bricks with solar electric during the day and use it at night, or heat them with wind power and use the heat when it isn't windy.
Show HN: An Express-inspired web framework for Rust
Graphul is an Express inspired web framework using a powerful extractor system built on top of Tokio, Tower, Axum, and Hyper. Designed to improve, speed, and scale your microservices with a friendly syntax, Graphul is built with Rust.that means Graphul gets memory safety, reliability, concurrency, and performance for free.

https://github.com/graphul-rs/graphul
None of those go out of their way to do so, and certainly not databases. Every database tuning documentation I've ever read says avoid swap at all costs.

Some just allocate when they need it until it doesn't work (cough Chrome cough), but that is a far, far throw from intentionally allocating more memory than the machine has, and none of them seem to do it to intentionally only work on a small subset at a time, even if de-facto that is what happens.

What sort of performance or reliability would you expect anyway from a database that intentionally loaded the entire database into memory first without even caring how much would fit?
You can wish all you like but it won't change human nature
What does SPoF even mean?

I could probably step into this system and be effective in it w/i a single month, probably less.

Is that a SPoF, or is the multimillion dollar system that no one understands well it's own SPoF?
A typical example page with synonyms and quotations (not all have both): https://carefulwords.com/above

I began this in late September purely on the whims of frustration with thesaurus.com, which does not bother to focus the input box! So I made my own site that focuses the input box. And because I wanted a thesaurus where I could type just the word in the address bar eg carefulwords.com/word to get my results.

It is very rough around the edges right now. There are far too many synonyms, which themselves are only organized alphabetically. It also does not solve some of my original problems with thesauruses, so I may take the site in a very different direction over time.

I think it should be possible to make something like a thesaurus that grants a bit more inspiration to the searcher. Now what would a thesaurus need to do that?
Unethical life pro tip?
I can recall getting a surprisingly intrusive investigation coming into Montreal as a tourist on an American passport in 2017.

Taking everything out of my luggage while I'm desperately trying to warn them that some of the socks are wrapped around a DSLR and lens I'm trying to protect from damage, fiddling through my phone camera (since there was nothing good on the new DSLR with like 40 photos of local insects). Evidently they were trying to find background evidence that my claimed objective-- visiting the Exporail museum-- was plausible. Who doesn't like trains (and it is, indeed, an excellent museum)? Fortunately, I had a photo of the Acela I took last year on my phone, and that seemed to satisfy them.

After all that, the agent chastised me because I followed my grandmother's advice and left CAD40 in the pocket of my suitcase in case I got my wallet stolen-- "It's very safe here". Is it safe here because you make random tourists feel like terrorists?
"Renewables open up a huge opportunity for exploiting the fluctuating availability and therefor price of energy."

Actually it is the complete opposite, wind and solar create a huge PROBLEM with its unreliable fluctuating output.
Is there any evidence that prohibition reduces harms from drugs?

My understanding was that it marginally reduced use, but significantly increased harms (due to impure drugs, interactions with criminals, treatment budgets being used for incarceration etc.)

It's probably drug-specific too. Making alcohol illegal probably caused more harm than making heroin illegal, since alcohol substitutes are often much more toxic than the real deal)
The Windows version of iCloud causes file duplication and corruption with Obsidian, unfortunately.
one of the best comments I’ve read on here. kudos to standing tall in the face of disagreement
Mushrooms Demystified by David Arora

Edit: this is the definitive resource for serious amateur mushroom enthusiasts in North America. It has a wealth of information on understanding the identifying characteristics of mushrooms, as well as keys to aid in the identification of many common genera and species. It's one of those books I find entertaining just to open and read at random. YMMV.
Adding such a restrction does not have to change GPL itself, it’s just another sentence applied as part of the license by the author.
Please don't take HN threads into religious flamewar. It's not what this site is for, and it destroys what it is for.

We detached this subthread from https://news.ycombinator.com/item?id=33211669.
How are the first two essential? If they’re useful anyone could improve on them
> they re-appropriated the word to redefine it to something else, an ideology opposed to socialism that was meant to empower the Volk

I was referring to the exact writing you reference, and it does not support the point that nazism reappropriated the word to mean something else.
> Heat pumps? For huge numbers of poor people across the world this a Marie Antoinette-esque gesture.

We were specifically talking about Europe. And there, lots of people even in relatively wealthy countries like Germany still use gas for heating. The government could definitely be encouraging/subsidizing the use of heat pumps instead.

Obviously the idea is for transitioning where it's economically feasible, not demanding that poor people freeze to death, jesus christ.
Kinda weird how the article focuses a lot on his legal career but seems to not say who he worked for (doesn’t name them and one link is dead), all the quotes about him are anonymous, and then a description of a linked in profile that appears to be inaccurate.
I couldn't write/ship an app like that.
Situations that are life or death should not be decided by someone’s narcissism
search: >'Metformin treatment for SARS-CoV-2'< @DDG : <https://html.duckduckgo.com/html/?q='Metformin treatment for...>

Metformin potently inhibits SARS-CoV-2-induced cytokine release in monocytes : https://www.news-medical.net/news/20210606/Metformin-potentl...

Edit; Added: search: >'Metformin treatment for SARS-CoV-2'<,

as Metformin *potently* inhibits SARS-CoV-2-induced cytokine release in monocytes< paper may not be peer-reviewed,

Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore,

should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information

Also added; Metformin : https://en.m.wikipedia.org/wiki/Metformin
A very interesting drug. Unfortunately, it's generally not covered by insurance unless a patient has already proceeded to an additional (more serious) health complication like diabetes. Thereby necessitating another pharmaceutical intervention, this time with a lifetime of treatment attached.