skysight-inc/HackerNews huggingface dataset:
I think a very interesting field of inquiry into oral microbiota is a broad evolutionary approach. There was a study published in Nature Genetics[0] showing big changes in oral microbiota corresponding with Neolithic and Industrial dietary change. Modern oral microbiota are markedly less diverse than historic populations and the, much more developed, study of the gut microbiome shows us that very microbial diversity very often corresponds with usually-commensal microbes becoming pathogenic. It seems that cariogenic bacteria became dominant, apparently during the Industrial Revolution.[0] But we know that pre-Neolithic hominins very rarely had caries.[1] Despite affecting anywhere between 60-90% of schoolchildren in industrialized nations, less than 3% of P. robustus specimens examined had dental caries.[1]

What's MOST fascinating to me is that this dance isn't just our mouths vs the microbiomes. There's now considerable evidence that it is more likely to be the host response to the bacteria that leads to the tissue changes noted in gingivitis and periodontitis[2]

[0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996550/

[1] https://www.sciencedirect.com/science/article/abs/pii/000399...

[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692012/
I still like it. I think there's some glaring flaws. HN seems to glass cannon - it's probably top 0.1% in tech, but below average in a lot of things. You find the topics where Sturgeon's Law kicks in and stay far away from them.
This is terrible advice.

I’m sorry to be so harsh, especially here, where I know etiquette is important but this comment needs to be shut down.

The dismissive suggestion that alcoholism can be cured simply by using “self-control” is toxic.

Yes, self-control is PART of it, but to say that it’s “all about self-control” is damaging.

There’s a reason the person is struggling to control their behavior. There are underlying problems.

Sociological? Biological? Societal?

Yes.

Working on those problems takes great effort and many cannot do it alone.

Yes, SOME can do it on their own but the dismissive anecdotal examples are more damaging than helpful.

People suffering from addiction are beat down. Exhausted.

Yes, they still need to help themselves but they also need support from others who can guide them to a healthier life.

Would you tell someone with a broke leg to use willpower to fix it? No, of course not. You’d get them to a hospital.

It’s the same here. The advice needed is ‘where to get help from professionals that can guide them through their problems’.

The only organization I know like that is AA but I’m sure there are more. Someone who knows, please add support groups.

Take the first step and reach out to a group. Give their program a genuine try and beat this problem one day at a time.

One day at a time.
I’ve used Anki nearly every day for the past decade or so, and I agree it is not very efficient. It’s too passive. Like you said, assembling your own deck, deliberately going through the material in more natural chunks and actively processing it is more efficient.

But Anki makes up for that in consistency. I went through a deck of about 8000 cards and it was tremendously valuable. I could’ve learned the material faster with other methods, but only if I had the commitment to it. By contrast, opening an all every day on the train is a breeze.
The cores don't connect to each other; they connect to the shared cache. Existing layouts are probably near-optimal.
In what scenario can you read/modify virtual box vms on a shared system in which you can’t read enough of a user profile to compromise an active user session to compromise encrypted credentials?

Can you name any scenarios where virtualbox is used in a multi user environment where bare metal shell/fs access is possible that are actually real world? If so I would be telling those entities their architecture is wrong and they would probably save on TCO by re-engineering things.

Defence in depth is a legitimate argument under some use cases, but your argument seems to be in favour of over engineering redundant or theoretical security controls rather than creating actual defensible environments.
It’s a good question, and I’m glad that you posted it. I am in a similar situation.

For me, I am becoming wearier and wearier of drinking - but having the access to an external and accessible release is appealing. I don’t have advice but I do have a personal target: I smoked cigarettes starting 20+ years ago. And over the years I got distance from it little by little. Now I have, what I like to think of as, a good relationships with tobacco. I enjoy a cigarette once every 6-8 weeks. Sometimes it’s good and tasty and I enjoy the experience, other times it tastes like crap and I know I’ll feel even worse later so I cut it 1/4 in.

That’s where I want to get with alcohol (and I’m certainly getting closer).
Used it for my new app and it's working well, thanks for building it
Go look for Patrick Lancaster on Youtube since 5 years ago. And you will know you have been on the wrong side by saying false flag in Donetsk. American have been doing false flag even worst than what you imagined of Russian is doing since Teddy's time.
The technique that worked for me was replacement.

The idea with replacement is that it's hard to say no to something, but easier to say yes to something slightly different (a nonalcoholic alternative).

Don't have any booze around, but do have lots of seltzer and tea.
Is that website real? It looks like their design budget was negative dollars.
I looked it up, $50 per licence with a 100 licence minimum.

Shame, Id pay per licence if I could, but instead I’ll probably just block their traffic and breach their licence. I doubt they can legally enforce those terms in Australia.
I was once in a similar place in the rockies, 3h from Denver. It sounds exactly like there!
Closed source?
I'm from Los Angeles, where car culture reigns supreme. I suppose the equivalent would be eating in the car versus sitting alone in a restaurant or at your desk at work.
if you go one step deeper, the definition of drinkable is "suitable or safe for drinking", so technically, a beverage just need to be suitable for drinking but it does not need to be actually drank for it to fit the definition.

https://www.merriam-webster.com/dictionary/drinkable
Do you think that the folks from https://en.wikipedia.org/wiki/Alternative_3 are finally entering https://en.wikipedia.org/wiki/Phase_IV_(1974_film) of the roll-out of https://allthatsinteresting.com/project-blue-beam-serge-mona... ? ;->
I believe the current stable diffusion license is "responsible" enough.
>malware still grips both systems all the same

The amount of malware that regularly shows up in the Google Play Store is so large that tech sites have taken to warning users to be careful what they install from inside Google's walled garden.

>With malicious apps infiltrating Play on a regular, often weekly, basis, there’s currently little indication the malicious Android app scourge will be abated. That means it’s up to individual end users to steer clear of apps like Joker. The best advice is to be extremely conservative in the apps that get installed in the first place.

https://arstechnica.com/information-technology/2020/09/joker...

It's not that it's never happened in Apple's App Store, but it's certainly not something that happens on a weekly basis.

As that article points out, an Android apps ability to download code from random locations on the internet, install it and then execute it is a big source of the problem.
Went from 1 beer to 2, then 3. Then hard liquor. Passing out on the couch for months on end. Waking up with hangover.

Eventually went to the doctor to discuss my issue that I can’t stop. Yet I have no problem not to drink.

So I stopped drinking. Naltrexone for the cravings the first couple of weeks. Now sober. Don’t even miss it.
I just have a rule that I only drink in social situations. Since I only have enough real friends to count on a couple of hands that doesn't happen very often at my age, so it works for me. I never drink at home, I think that too easily leads to what I call "casual alcoholism" . You are not technically an alcoholic but you do it instead of more productive things like coding, playing video games, or (my) wood working hobby. Just sitting around drinking kills your liver and the rest of your health. Some few people seem to not really effected by it, but I have seen two early somethings get cirrhosis and that's kind of scarey. My papa pickled his liver for decades and it never happened and he died when he fell and hit his head at 89. I always felt science should study elderly like that to see why they don't get cirrhosis/lung cancer/kidney failure from 50-60 years of drinking/sugar abuse/etc.
That is indeed one way, thanks again!
Ah, Roman is the guy from RedHat who worked on Shenandoah GC. He has an excellent background on this and will be really glad to see when this is stable.
> I cannot shake the feeling that something significant has changed in the last 30 years.

Try the past few hundred years: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996550/

> The composition of oral microbiota remained surprisingly constant between Neolithic and Medieval times, after which (the now ubiquitous) cariogenic bacteria became dominant, apparently during the Industrial Revolution. Modern oral microbiota are markedly less diverse than historic populations, which might be contributing to chronic oral (and other) disease in post-industrial lifestyles.
The WW2 nuclear bombings of Hiroshima and Nagasaki predate any real nuclear doctrine. I don't think they are particularly informative of nuclear doctrine today. And yes, as the other poster says, Japanese invasion of the continental US is an absurdly unrealistic proposition - even if Japan had achieved all of its wartime objectives.
If you just wanted to see if a particular sequence was fungi, you could just use BLAST.

If you had thousands of sequence reads from multiple unknown organisms, then you’d have to implement a meta genomics pipeline.

All the software for this is already made. You take your sequence reads, trim them a bit, assemble them into “contigs”, and then map those contigs to known genomes in the magical tree of life.
The Giant: A new exhibit showcases the work of Diane Arbus
Boy they’ll be disappointed with Google randomly decides to cancel the product with no explanation. But hey, here’s eight new chat apps.
Many senior political figures in the US repeatedly call for regime change, coup, uprising, and worse...

... to happen in the US, and nobody nukes them either.
Sorry to hear that. Did you get your sequencing report? That can help you and your oncologist figure out next steps.
> I have a hard time saying no to a drink if everyone else is having a drink

Dig in deeper on this and then make yourself do it. It’s a good initial skill to hone.

The first thing is just saying no thanks when offered. This will be easier/harder depending on your friends. Ordering something nonalcoholic is a good. But next problem is being sober around your drunk friends isn’t usually such a fun thing. So you’ll ultimately need to just stay out of the bars, make friends that don’t drink that much, or alter your friend group nights.
Yep - TBF, I have no idea really.

I just see what I see on the news out of the US with headlines such as:

"Student arrested in Texas after walking to school with assault rifle just one day after tragic Uvalde shooting"

So it's understandable the world believes that Assault Rifles are purchasable by civilians in the US.
There is another chapter in the book about monopoly power and how to prevent it. It's been a while since I've read it though so I don't remember the exact proposal.

However Glen Weyl would probably say that the book is out of date and point to a model such as quadratic funding, where taxes are allocated by private individuals to fund public goods.
I didn’t know China invented electric cars. Last time I checked, they were invented sometime around mid-19th century in Europe.
And yet, somehow, some amazing features have been added to Excel recently. Dynamic array formulas and lambda functions have taken my Excel use to the next level. Let alone new standard functions (e.g. sort, filter, misc. text-manipulation functions).
Yeah, the issue of everything working perfectly exactly as it was 8 years ago. Such a bothersome issue. (/s)
I decided not to drink for a year and stuck to that commitment. Simple as. If I can't attend an event without drinking I didn't go.

I'm hopeless for quitting my compulsive browsing habit though. I keep trying and relapsing.
Pick one of the most popular keyboards used by your target and reuse it. That's how I'd do it. It's not going to get everyone but I think it's a legitimate approach.

The alternative methods looking at the time between keystrokes seems more reliable.
> You can block Google analytics

You can't block googleapis or reCAPTCHA and still have the site function properly.

> Facebook didn’t force your family to use it

But I still don't get to opt out of having an facebook account, or opt out facebook collecting my personal data, or opt out of them using it for whatever they want.

> I’m sorry you were forced to choose a career where you get to sit in front of a computer everyday probably making a lot more than people in a factory.

I'm not saying it's all bad, or that it couldn't be worse, I'm just saying you don't always get a choice in things and often the "choices" you have are false choices or forced choices.
1. I heard that oral health either predicts or is a causal effect in dementia and Alzheimer’s. What’s the mechanism?

2. Should we be having micro biome implants? And more ridiculously, but not really, should we have “celebrity micro biome” products?
Or you go around intentionally pissing off rich people in order to bait them into buying your home for double its value simply by doubling your property tax.
That article is about financial exploitation (a very real problem for which Bernie had a great solution - offer basic retail banking at the post office), not about inexpensive, sh*tty consumer goods.
API changes are way more common than adding keywords. That’s one difference.
i need something like this for rosetta 2 lol
Do you have a picture of the old site?

Dying to see it now, lol
Economics Nobel Should Come with a Warning
Yup, and it's the exact same reason that "Mozilla/5.0" and "KHTML, like Gecko" are both still in that user agent string.
Aside from the glaring irony in this comment, one also has to wonder whether or not the Russians have any kind of nuclear dead mans switch in the event that someone drops an IED on putin.
I for the most part agree with all your points on Desantis. Medical marijuana in Florida is a joke, I'm pro legalization. Not a fan of gambling personally but to each their own. On a personal level I think he's a Jerk. So with all that said as someone in my 40s that has only voted Democrat before, the fact that I am voting for Desantis shows how concerned I am with the social engineering going on in the country.
The point is usually the "model minorities" are the subgroups that are treated well by the rest of the population.

That's why they can unleash their true potential in the first place.

So is that a good argument for treating other people badly?

That should be especially clear in a country like the US where the original inhabitants have been wiped out and everyone is an immigrant.
Oliver Stone showed Dr Strangelove to Putin in 2015. https://www.youtube.com/watch?v=rdxls8uC4DA
Most things are faster than gzip, and many of those things have smaller outputs as well. Brotli at level 2 produces the same-sized archive with this input, in just 3.4s. Gzip even at level 1, with a 10% larger archive, still needs 6.5s. zstd, at level 1, produces the same size as gzip -1, in 1 second! zstd, cranked up to 9, makes a 20% smaller archive in 7 seconds, less than half the time of gzip -6.
How do you explain above reference to Jefferson including the phrase "merciless Indian savages" ... "whose known rule of warfare, is an undistinguished destruction of all ages, sexes and conditions" into our nation's founding document? A lapse of Jefferson's magnanimity or did he just have a really low opinion of himself?
I hope this was a joke, but if not, this is not good advice for most people.

Having kids does not solve substance abuse issues, mental health issues, relationship issues or any similar problems. People may believe that having kids will fix whatever problem they're facing, but instead find that it just adds tremendous amounts of stress, burden and additional hardship on them.
Is there an OS and hardware combination you suggest for 18 hours of Firefox, TypeScript, and Docker?
Is there any more information from someone who isn't them?
I wouldn't be shocked at all.

It's a big club, and you're not in it - George Carlin

Yes, I'm sure there's some technicalities that can be found to "justify" this but I'm also sure there's a lot DMs going between some well-connected people regarding this now deleted account.
I flagged this because it's tacky to buzz-market your own product without disclosing it.

The entire article is a little offputting and inauthentic because it's written by someone who is paid to like Vocal and disparage Zoom.
The Russians didn't keep the doomsday machine secret to improve its effectiveness. The Russian ambassador says:

"It was to be announced at the Party congress on Monday. As you know, the Premier loves surprises."

You don't want to announce that you are building the machine before it comes online, because that gives the adversary an incentive to strike before it is finished; you want to bring it online and then make the announcement shortly after.
Thanks for that information, I wasn't aware until reading into it from your suggestion here that it's what underpins the encryption in btrfs, which is something I've experimented with a bit but didn't realize had zstd as a part of it. Very useful!
> "it works for me" gives very little information about the software you're using.

I don't think so. It says that the software satisfies the basic requirements of its target audience, and gives a hint as to who that audience is.

On the other hand, if you receive the opinion of some self-proclaimed expert, I think you're receiving less useful information. Experts are typically a small percentage of the userbase, and among experts there can be vastly different opinions depending on their specialty. Ask an Android dev to review vim, and an operating systems dev, and you'll get wildly different responses. If you ask a generalist software developer, you'll likely get less noise.
Adam Curtis: Russia 1985-1999 TraumaZone: Collapse of Communism and Democracy
Interesting how this article points out that foods like fish and eggs are high in sulfur contribute to gum inflammation, but that omega-3 fatty acids can help reduce this inflammation. I guess that piece of salmon may counterbalance itself.
This blows my mind, I just this last week learned about xenobots on Lex Fridman's podcast with Michael Levin. I had no idea how fast evolution can work...
I use https://librewolf.net/ which I think might be close to what you are looking for?
Having a plan B for things is a bit silly sometimes. If you need to parse some data, your plan A is to write a parser, and your plan B is...to write a parser in a slightly different way? Pair program as you write the parser? That's not really plan B, it's just redoing plan A if you mess up.

Plan Bs make sense for external dependencies, but for internal work they imply your current solution has feasible alternatives, which is often nonsensical.
Don Lancaster's site has info on canals in his neck of the woods.
There's a great selection of craft non-alcoholic beers on the market these days.

My personal favorite is this one: https://athleticbrewing.com/products/downwinder-gose-non-alc...
Just keep building things. When you can't build it, google it. When you can't google it, ask. When the "internet" doesn't know, find the one guru that knows everything about that very specific problem. Repeat until you're that guru guiding others.

All that with just a hint of sarcasm. Just build :)
Al Jazeera runs a ton of Qatari propaganda and their Arabic version is especially full of it.
What's your favorite intro-to-game-theory book?
An L3 who remains an L3 will get PIP'd. If they're tenured it's possible, but if they're forever senior people will start doubting them. Staff, I think, is the first level that can really be "sat" in. I say sat in because at Staff "coasting" probably has a different definition that's what being used by the phrase people are referencing. It's more like you don't have to chase advancement to stay employed.
This is the opinion of one of those "lovely" people. If this is how a significant section of pollution thinks, good luck cleaning the shithole
I consider this a feature. It convinced me to move two windows laptop "servers" to pop_os LTS. That's fine windows execs, keep digging the grave of your OS, we all know you want everything online so you can charge monthly merely to use an "OS"
I did a lot of personal development and spiritual work that taught me very practical tools for 'being with' the uncomfortable sensations that arise around choosing not to drink. Armed with the confidence that brought me, I simply lost interest. Surrounding myself with other people doing the same thing also helps a lot I'm sure. I didn't keep alcohol in the house until someone was moving and gifted me some.

Occasionally I'll have a drink, but I have higher sensory clarity now from meditating and I typically find it neutral to unpleasant, unless it's just the right situation.

What also helps is taking other lightweight mind altering substances for evenings when I want to have social fun. I recommend going down the research chemical rabbit hole and looking at the dissociatives especially.

At the end of the day though, it took a lot of time and drastic lifestyle shifts over years. For what it's worth, I don't think self discipline is the right approach, for the same reason it's not an effective way to treat any other addiction.
Russia 1985-1999 TraumaZone: Curtis exceptional collage of conflict and collapse
Most of these stories came in the form of blog posts by Raymond Chen in his blog The Old New Thing. It used to be even more fun to read in its old form and layout, and I am fairly sure not all his posts survived the move to the modern "devblogs" platform. But many of his posts were published as a book by the same name. Highly recommended, and a great gift!

https://devblogs.microsoft.com/oldnewthing/

https://www.amazon.com/Old-New-Thing-Development-Throughout/...

Fairly widely read also by Joel on this topic: https://www.joelonsoftware.com/2004/06/13/how-microsoft-lost... (not the article cited on Twitter; links to Chen's posts sadly broken)
For anyone who wants to try this, zstd -T0 uses all your threads to compress, and https://github.com/facebook/zstd has a lot more description. Brotli, https://github.com/google/brotli, is another modern format with some good features for high compression levels, which also has Content-Encoding support in web browsers. You might also want to play with compression levels (-1 to -11 or more, zstd's --fast=n); they may not map 1:1 to gzip's.

One reason these modern compressors do better is not any particular mistake made defining DEFLATE in the 90s, but that new algos use a few MB of recently seen data as context instead of 32KB, and do other things that would have been impractical in the 90s but are reasonable with modern hardware. The new algorithms also contain lots of smart ideas and have fine-tuned implementations, but that core difference seems important to note.
I feel vaguely-neutral/negative toward it. It plays somewhat annoyingly with things like bookmarking (mitigated slightly by the fact that infinite scrolls are usually generated content anyway so bookmarking them is probably meaningless) and are trying to tempt the user into endless scrolling (but I guess it is our responsibility to resist the temptation there).