skysight-inc/HackerNews huggingface dataset:
No, it's not as simple as that. The probability of self-replicating RNA arising by random assembly of bases is very low. There was a good Nature article [1] published a couple years back that digs through some of the numerical issues. (And a good, more layperson oriented summary as well [2].)
The gist is that a self-replicating RNA sequence would have to be at least 40 nucleotides (and possibly even as long as 100), but the probability of randomly synthesizing a 40-nucleotide long sequence that happens to be self-replicating anywhere in the visible universe over the span of 13 billion years is effectively zero.

To be fair, the probability gets closer to one if you expand your view to include the entire universe and assume that it is many, many orders of magnitude larger than the visible universe. But my take away, at least, is that we are not dealing with a situation where random assembly of RNA is so likely to generate self-replicating sequences that abiogenesis was effectively an inevitability. That was the narrative I was sold in grade school and undergrad, but it appears to be wrong.

There are a good number of free parameters in the journal article that I linked: The fraction of RNA sequences that are self-replicating, the fraction of planets that are habitable for life, the average decay rate of RNA on a habitable planet, etc.

You take can take issue with the empirical estimates for those parameters, but that points to missing pieces in the framework: Was there a chemical process on early earth that stabilized RNA oligomers that no longer exists? Are self-replicating RNA sequences more common than we believe? If so, why haven't we encountered more of them in nature? And so on. In my opinion, these are the truly interesting questions, not whether nucleotides and amino acids can form spontaneously.

[1] https://www.nature.com/articles/s41598-020-58060-0

[2] https://mathscholar.org/2020/05/the-origin-of-life-in-an-inf...
After getting an M1 Pro, I don’t worry about battery life on laptop at all. This is such a huge quality of life upgrade and competition has no answer for this. I switched from Linux because of this.
Oculus is a legitimate French word though. Same meaning as in English.
Modula-2 and Oberon (2007) [pdf]
Google's denial takes nothing away from the credibility of this rumor. Google isn't going to deviate from their own preplanned PR campaign on any product's demise just because a rumor leaked. That doesn't mean this rumor is true, only that the denial has no informational content for evaluating the rumor.

Yet on the other hand, if Google really wanted to refute the rumor, they'd say "It's not true, we have a firm roadmap for improvements and expansions etc." And actually have a published roadmap they could point to. Instead they claim they're working on getting new games but from what I can piece together we're about 60% through 2022 and Google has only released 37 of the promised 100+ new games that would come to the platform this year. They could make up some ground but they're not on pace for it.
Right because 600m wouldn’t be attractive elsewhere.
This is a provocative and unnecessary rewording. Her meaning is plain. Tons of things affect relationships negatively - divorce is only one result of infinite, and you may phrase each negative event as "increasing the likelihood of divorce", but it serves no purpose.
Flickr is now independent, but it was part of Yahoo for so long I’d guess most people having all their photos in it probably used a Yahoo account. I’ll confess I tried accessing mine after a years long hiatus and it didn’t work (endless password resets)

On alternatives, which storage/sync and management service do you see working at the same level as Photos ? I’m genuinely curious and would move if it matches up (Basically, what is the Gmail->Fastmail like go to alternative for Photos ?)

Image identification looks to me like a very fringe use for a photo storage service, or perhaps you’re referring to searching all your photos for specific keywords ?

PS: Reminds me of the photos services curse from “The Prompt” podcast, where every time they’d present a competitive photo service, like Everpix, it would go out of business or something horrible happen to it a few months in.
I suspect (but have no data for) that a significant chunk of content on social media is memes and still-image-video. Those are likely to be easy to dedupe or compress aggressively
Exactly. Google has such a strong reputation for killing products now that I’m just now willing to invest in anything they create any more.

IMO they need to fix the internal corporate culture and move it away from short-term OKR goals and promotions based on launching new stuff and a bit more towards helping to maintain and grow existing projects.
Lotteries are criminally stupid, and running them is criminally evil. Shame on all governments that do so, including mine.
Does it work only on Adobe Acrobat? Would it be flagged as malware if I sent it to some recruiters through Gmail?
Not the op, but I've just switched away from spinning disks recently. Kinda.

I have a NAS of 4x 8TB WD Red Pro; and a a desktop with 4x1 TB of nvME and 1TB of (grandfathered) SATA SSD.

For batch photo processing (i.e. lightroom) spinning disk is really sub-optimal. I'd rather have a 256GB or 512GB nvme and process batch by batch (and then offload to NAS), then a 8TB 7200 RPM HDD with all my photos.

To OPs point - depending on shooting style, you might easily do 300GB+ over a single wedding (primary + secondary shooter, 2 cameras each, 46MP, 14-bit uncompressed, spray-and-pray style).
I prefer to think of the scientists working on solving balding as Larry David or George Constanza-types. Bitter about their hair loss, kept going by the promise of a better life in the future through hair.
TA is awesome! I'd love to take credit for it, but that's a different Chris Taylor.
The first sentence of the article is not necessarily correct since anyone worldwide can legally buy tickets though a ticket-purchasing service.

For example, in 2015 a man from Baghdad bought a ticket through a service and won a $6.4m lottery without leaving Baghdad.

The article assumes everyone buying tickets is an American, which is not true.
What is he going to say to you? That the Serb committed mass genocide etc. The guy is here and has to make a living and not create enemies above his pay grade. Saying as someone who has met many Bosnians with severe PTSD who were there at that time.
Exactly, there’s a big difference between “I’ll grab a ticket at the gas station as a laugh” and poor pathetic exploited gambling addiction.

I used to sell tickets at a convenience store and I’ve seen some pathetic people for sure. But for these mega jackpots I think it’s mainly casual people buying a fantasy for a couple days of day dreaming.
There's a very interesting Brazilian case: Herbert Vianna, singer of the band "Paralamas do Sucesso" crashed his ultra-light aircraft and had some brain damage. He can't walk anymore, after the accident he couldn't speak Portuguese but could speak English. He had to relearn who he was and quickly came become to the successful artist he always was. He even recovered hos political views.
With a proper package manager that keeps track of the installed files and a proper permission system, it doesn't matter where the files are.
Were you seeking arbitration as a consumer? It should have only been like a couple hundred dollars.
The game allowed early access, so you could play it while it was being developed and I think you gain some in game stuff on final release.
By 2015 Zillow was already well entrenched, what was your differentiator?
I'm curious: how many free trials did you get for ProxiesAPI via this smart tangential post? ;-)
Second question: except on pricing, how would you say you can outperform BrightData?
I can also recommend sketchyVim as I think it just uses your normal .vimrc file for its configuration and it’s FOSS.
Do you have a newsletter I can subscribe to
https://www.theguardian.com/us-news/2016/oct/25/donald-trump...

"Donald Trump said on Tuesday that Hillary Clinton’s plan for Syria would “lead to world war three” because of the potential for conflict with military forces from nuclear-armed Russia."
> When the hair grew back it was thicker & darker than it has been in 30 years

So my initial hunch during the chat with my barber, "If we have found hints to cure to baldness - and hidden in covid, to make history more interesting..." was probably not just the humour of the moment, after all!
You can still drive in Europe. Cars and roads still exist.
What are the new advances that have you excited?
Are you arguing that there was some direct intervention during the origins of life? Like, an intelligent being stuck a probe into a chemical mixture and tipped it towards generating cells?

Or, perhaps you're arguing that the rules of the universe were designed in a way that guaranteed that life would arise?

Something else?
And very strange things like the Dance Marathons of the 1930s: https://www.historylink.org/File/5534

Dance Marathons (also called Walkathons), an American phenomenon of the 1920s and 1930s, were human endurance contests in which couples danced almost non-stop for hundreds of hours (as long as a month or two), competing for prize money."
That’s my point. Organic chemistry is not like your construction materials (or silicon computers). The organic chem functionality for nucleotides to begin organizing into repeating patterns exists. We know it does. And while we might not know the exact reactions that it took, they are highly likely to exist, and were arrived upon randomly.

If you arrange your biological soup a large number of times randomly, you will eventually land on a pattern that causes other nucleotides to arrange in a similar or improved pattern around it.

Not too dissimilar from thinking about the creation of specific atoms through various astronomical processes.

Even if you need to believe in god for some reason, it’s not incompatible with god defining the organic chemical reactions that enabled life to form via random interactions of nucleotides until they happened to land on god’s lucky number
Jon Masters does: https://twitter.com/jonmasters
> If a separate top level comment were made about how poor people aren't on the map then I wouldn't be arguing that.

Well that's precisely one of the point I was making: that people only care more about VISIBLE inequalities (the gender) which are, in my opinion which you can disagree with, a lower factor of actual inequalities in societies.

At the end of the day I'm not the one who brought "inequalities for women" about a cool map which had a priori no political message. Everyone is free to make their own point of discussion, and you didn't jump out of your seat when this first point about women was made to say it was out of context as you are doing now.

And as a french person it's insane that your culture is so confrontational and tribal that "all lives matters" has to be a divisive statement. Hope you guys will heal at some point.
> It [Ubuntu] spends 12 seconds running modprobe running a shell running modprobe, which ends up loading a single module.

Is this a typo!?
does switzerland dirty
Then use plotly bud. Why rag on tabler though? It’s beautiful and provides devs a quick way to get started on a new project without having to think much about UI and lightly customize and have something that looks very professional. And it’s free.
I think it’s easy to call something out as primitive but what changes could be made and how much impact would it have? It doesn’t seem like our freight trains are the bottleneck when moving goods around the country.
DevOps is like what happened to DBAs, now devs get to do another role while still being responsible for their other roles without extra compensation while eliminating a whole job (ops or dba).
They said “for messaging”. Twitter and Facebook aren't messaging apps.
> this reputation of Google doesn't exist.

To be fair, most gamers I’ve talked to don’t even know what Stadia IS.

By definition, gamers play games. To do that, they almost always own a console or gaming pc to do so. As a result, they have no need for Stadia in the first place.
I do a similar travel distance (between 213km - 230km by car on the highway) monthly minimum between Amsterdam - Brussels taking the inter-regional train (NS) (understand the "slow") : 2h45 for around 25-29 EUR each way if booked a few days in advance. The fastest one with the Thalys is 1h55 for around 90EUR. Driving take around the same time than the slowest way ~2h30.

The Amtrak trains are slow? I mean even adjusting for the potential 40 to 10km difference and the fact that the NS does between 8 to 10 stop depending where you want to go out in Brussels or Amsterdam, 4h for a 241km trip is slow.

It is a bit cheating as if you want to do Brussels - Arlon, a 190-ish km trip inside Belgium, it will take you 2h45. And if you want to more or less cross Belgium from North to South (Oostende to Arlon), 310-ish km trip will take you around 4h15 by train and between 3 to 4h by car due to the fact that you will take the Brussels ring road. So small country, yep. Still 4h for 241km is slow.
Please note that the author never specifies that their context is marketing or management. They instead use a far broader term, “computing”. It would be very difficult for huge swaths of developers to do their job without using OOP and other attendant terms.
Maybe better said as 'several games provided on stadia have crossplay'. I wonder if there is a better model of a user buying a license for a game, specifically a non-'live service' style game, and being able to use that on any platform that they provide the game for. I find myself buying two copies of more than a few games these days. Mostly picking it up on a more mobile platform like the switch after buying it on the pc.
Is the registry used for IO - like The mac IO KIt ?
Alternative take: there's strong demand for numbers games, and the government, whose spending is at worst weakly correlated with social goods, and who is not profit-motivated and therefore will do less to encourage problem gambling, is better than the alternative in practice.
Thank you for playing! Glad we could give you a boost. I'm super appreciative of all the Fallout fans I've met over the years for doing the same to me.
They pay for college tuition and books in my state.

https://en.wikipedia.org/wiki/HOPE_Scholarship

Edit:

> As of 2006, more than $3 billion in scholarships had been awarded to more than 900,000 Georgia students. As of 2018, HOPE has already helped around 1.8 million students from Georgia enroll in college.

One negative externally that would happen anyway (eg. sports betting) turned into a positive one.
Turn any Java program into a self-contained EXE
a bit off topic, but is there like a more affordable lego like alternative? it really disgusts me how expensive lego and litigous they are. so many Americans live in poverty who would love to get their kids to play with lego but can't because its ridiculously expensive.
Just apply for jobs on indeed for 4 hours a day and go through all the coding challenges and bullshit interviews and rejections. Stop making this an impossible mission. Companies are paying you to solve problems through software and yuo can't solve your own? fuck outta here
Private Buyer Spends $6.1M on Dinosaur Skeleton as Scientists Fume
The monthly fee is optional, you don't have to pay it to be able to stream games you have paid for.

It gives you access to a library of additional games you don't have to buy.
I'm struggling with the idea that React is a primitive used to build a Web Framework.
Question. I looked at the demos and the documentation. It seems like Retool can do low volume ETL. In my case, I want to pull Smartsheets data into Tableau which is our reporting tool. Is this an appropriate use case for Retool? Specifically, I want to use the Retool online version.
South America, as an example
I always have do not disturb on but I add my family, friends and certain coworkers to my favorites list. There’s a setting that allows contacts in your favorites to bypass do not disturb. Calls always come through.
> If you throw construction materials up 1 quadrillion times, how many times can they randomly fall in the form of a house?

It depends on what you call a house.

It will probably never fall in any given expected shape.

It may very well fall into multiple configurations that someone arriving at the scene after the fact, and without prior knowledge of what you expected when you run the experiment, would call a "house".
Human DNA is a lonnnng way down below the timelines and processes we’re talking about buddy.
Youngsters and modern times have been condemned since times immemorial

https://redd.it/7btv14

https://xkcd.com/1227/
> Why pack so many different things into a single project?

So I can build a dashboard without deciding on a layout tool, then deciding on a solution for charts, etc.

I do not consider myself a frontend developer. I'm just not interested in spending time learning about a bunch of UI tools if there's a framework that does it all.

This is appealing to me- the less I have to think about the implementation of the presentation layer, the more I can focus on the data processing, persistence, API... the stuff that _I_ care about working on.

Not trying to argue, just one answer to your question.
And how much tonnage moves on your "smart" rails? I'll let you pick the metric.
It's not just the strict denotative meaning. It's also the valence and emphasis of the statement. It doesn't concentrate the mind on "what if it disappears?", but on "how likely is it to disappear?", to which the (supposed; bullshit) answer is 'not likely'. Someone might - on rational analysis - know what it means, and still come away with a better impression than if they said it outright.
Not having to install something does not even start to be "the most empowering thing we've ever invented" in my book.
I've heard but don't know if its true that SSD storage can constantly suffer data corruption if its not powered. It needs power to keep refreshing stored data.

Something that maybe spinning disks don't suffer from.
They are still working on it, but have made significant improvements.
Posted on 8th of July 2022: "Our latest improvements look to deliver an average 50% reduction in start time after a fresh install compared to Firefox 101, consistent across a range of distributions and platforms." ( https://ubuntu.com/blog/improving-firefox-snap-performance-p... )
Gp is referencing US political slap fights from the last week (Biden admin declaring US is not in recession).

It’s a joke comment.
> If he had written the novel today it probably would have been something other than MAD that nearly wiped out civilization twice.

Maybe last year, but we're back to nuclear sabre-rattling and great-power conflict now.
If someone is considering the “store at home” route and this makes their head spin then consider just buying a prebuilt nas. You pay for someone doing this for you, but it has similar monthly price in the long run.
PATH can get emptied and the directory of its own executable is retrieved before a secured app shells out to another app.

I think it’s great that you think it is “trusted”, but I prefer the “trust but verify” approach.

That’s why using a separate hardware flash chip, that cannot be controlled by CPU instruction due to a hardware switch, has become that last bastion of security nowadays.

It is just that it becomes an inconvenience for ease of use in these days and ages.

Trade offs.
i don't want the bezels, but it's what i have, and the notch is just as unappealing to me, along with faceID and no home button. i'm hoping to skip the notch when i upgrade.

the back would be ok, but one of the reasons i like the side button with fingerprint sensor (or in-screen) is that it can be face up on a surface and you can still actuate the sensor. it's not that big a difference, but it is slightly better UX.

i also like the fingerprint version over faceID because it's not 2 steps to open the phone most of the time, but still gives you the option to see the preview screen when desired (pressing the home button with the fingernail/fingertip).
I think the point is that 60 fps is not a representable value in the gif binary format, just like (int pi) can be either 3 or perhaps 4, but never a transcendental number.

You can have a magical decoder that circumvents this, but that's no longer a gif.
That’s completely valid. I do the bulk of my work in my current internship in Machine Learning & Data Science codebases and there is no other language which has anything close to the ecosystem of libraries/tooling that Python has in this domain while also being a suitable general purpose programming language. I don’t have much experience with Matlab/Mathematica but I hear Matlab is decent for Machine Learning - but I don’t want to have vendor lock-in. That leaves me with C++ or Julia. C++ is not the most ergonomic language and adding manual memory management isn’t an ideal. Julia looked promising and I have heavily considered taking a deep dive, but ended up being deterred [0] - I feel like these are pretty major problems to exist for a language of this point in maturity.

[0] https://yuri.is/not-julia/
We really need Japan on this map :-)
Let me know when I can celebrate the federal holiday Jeff Foxworthy day and go down to my locality's Kanye West Boulevard
But the example with multiple selectors and & at the start is unclear due to the precedence of the @nest operator over the comma:

/* @nest always */
@nest & + .baz,
&.qux {
color: red;
}

It's clearer perhaps with different nesting, but that's fragile and a pain:

/* @nest always */
@nest & + .baz,
&.qux {
color: red;
}

At least with option 1 you only end up with this issue in the uncommon case of multiple selectors and a non-leading &.

/* @nest */
& + .baz,
&.qux {
color: red;
}
Is that much money a month really a concern? It seems prudent from a business perspective for Dropbox to not cater to price sensitive customers.

(I have a Dropbox annual plan)
If you use FastAPI with Tortoise ORM it looks like there's an Admin Interface that uses Tabler:

https://github.com/fastapi-admin/fastapi-admin
yah, headphone jack isn't a deal killer, but i do like having it. an adapter is ok but not great.
> But the demand from the community for this feature has been so far pretty low.

Makes sense since most read queries can (probably) be performed already with EdgeDB.

But my point about executing raw SQL was regarding having an escape hatch for features like listen/notify, etc.

I guess the solution is that for now apps will need a second PG client. Do you anticipate any problems with that approach?
It would be nice to end the drug war and put lotteries under the same management as Portuguese-style state drug distribution.

Also nationalize coffee chains for same reason lol.
Facebook was popular in the era when it wasn't used as a people directory however. It was used as instagram is currently until older people came in and the website became very commercialized.
That's true in that specific context (most websites in Safari) in that specific orientation. The extra screen real estate you get in native apps, or even Safari in portrait orientation is not nothing.
Ok, granted, screens today are more hi-res, and use transparency and other shader effects that weren't available in 1995. Also, VS Code is a much more advanced IDE than Visual Basic 4 or Delphi 2 (although you could design a UI graphically with the latter two, but not with the former). But my general point still stands: the applications today aren't 1000 times better than in 1995 (except possibly games), so why do they need 1000 times more memory?
It's not about company loyalty, it's about whether you actually believe in any of this tech. And you're supposed to, when you're a director with PR duties.
Micron is killing it these days, and it's all thanks to Gurtej Sandhu.
AWS Lambda and Django with SQLite