skysight-inc/HackerNews huggingface dataset:
Agreed, it's hard to imagine voluntarily embarrassing yourself in public as badly as the author has done here.

"When I went to college and met for the first time a good number of vegetarians and vegans, I used to blow their minds with this argument"

Indeed. That must have really been something. Well, he won't say anything to make us thinks he's positioning this in less than good faith, then?

"Honestly, fuck crabs"

Ok. but...

" but really octopuses are pretty horrible too. Oh, they’re smart, but, similar to crabs, they’re cannibals. They spend most of their time cavorting in a midden pile of prey bones."

Midden pile?

"If your cats were big enough, they’d eat you. Feline fillets are simply turnabout as fair play."

Cats?

"we should obviously be eating hyenas"

I'm done. Seriously, it's this guy https://as.tufts.edu/biology/people/faculty/erik-hoel ? what a waste of intellect.
The Witch King would immediately seize the One Ring for himself.

Although the notion of a ringwraith singing and dancing is amusing.
i pointed that out below and got downvoted.
I think that chart shows that things are going back to normal. The reason weekly earnings were at an all time high in q2 of 2020 is because the low wage earners all got laid off because of the pandemic. Now that things are going back to normal, the low wage earners are going back to work at approximately the same real wage (although nominally it's probably a bit higher because of inflation).
> Yes, it has a very nice model of what sequences should look like in 3D.

A structural model, you would say.

> That model is derived from experimental data.

That doesn’t make it a template-based model, or a homology one.

> if I give AlphaFold an MSA of a new, unknown protein fold (substantively away from any known fold), it cannot predict it

That will depend on the number of effective sequences found to derive couplings. Domains with novel folds usually have a low number of remotely homolog sequences and for that reason the method will fail, not just because they are novel.
It appears, once again, the people trying to refine the word are accusing the people keeping the historical usage as the changers. It's projection all the way down.
To refine the analogy a little more then: regarding the algorithms, maybe it's more like direct democracy but with a really powerful propaganda department (that's run by a sort of evil AI) influencing lots of votes?

I very much agree with everything else you said.
Godot ~3.2+ has support for a slightly older version of C# via Mono, I think it's the equivalent of .NET 4.8.

IIRC (and this could be wrong / have changed since I last looked into it) the idea was to re-work this in Godot 4 to provide more like bindings, so that users could opt to use Mono, .NET 6, CoreCLR, NativeAOT, or whatever version they preferred.
Make sure it includes their spouses or the marital unit.
> Academia feels like such a minefield though.

Yes. Get a PhD then leave for industry. The university system will be permanent decline for the rest of our lives.

Another instance of "zig when the crowd zags".
The content promoted by the algorithm results in higher user engagement because people like it. If they didn’t, the algorithm would have been changed to promote other kinds of content instead.
We can accept that lots of people believe 2 consecutive quarters of GDB decline define a recession, while also admitting that the group that officially defines a recession in the US hasn't done any sort of Orwellian redefinition at all.
> I’ve written before about longtermism, the idea that future lives carry moral weight—in this case, there will be millions of humans on this alien world that never exist if you choose (b) and abandon them to their fate on the hostile planet.

The idea of it automatically being better to choose the outcome where more future lives will exist seems problematic to me.

If it is better to have animals living miserably in factory farms if it means more future animals will be born (even if those animals will live miserably in factory farms) and that has moral weight, is there also a moral obligation to give birth to as many children as possible even if you are going to mistreat, neglect or abuse them?

I think most people would agree that it is better not to have children unless you will be able to avoid mistreating, neglecting, or abusing them, so wouldn't the same apply to animals?
If you're eating farmed plants, then there is a lot of environmental destruction and animal death/suffering behind that, too.
I'll forward all instances to you. I have 3 cards from support that I haven't tested yet but look like they have a different batch number so I'm hoping they will work. I won't need them now since all my testing is happening in live but I appreciate the offer.
Not to mention we've bred many species beyond what nature would ever allow. Many broiler chickens can't support their own body weight.

https://journals.plos.org/plosone/article?id=10.1371/journal...

> At a mean age of 40 days, over 27.6% of birds in our study showed poor locomotion and 3.3% were almost unable to walk.

And keep in mind we're talking about 60 billion chickens annually.

https://www.humanesociety.org/news/super-size-problem-broile...
Pandemic started in December 2019, gas prices started getting high in early 2021 after keystone was cancelled and the Biden admin began slow rolling drilling permits.
UP, Ultra Pure, couldn't find it in the States, they sell it in Chile, in Liga Chilena Contra la Epilepsia, that place has the best prices. It's clearly the best, comes from the clean waters of the South Pacific, it's palpably purer.
what new medicines have come out of europe recently? (serious question)
Either you want feedback and post your code on something like github/sourceforge or you don't and post it on an ftp or http site somewhere.
He's extremely mysterious and in a good way. He is one of the only characters able to just casually put on the one ring with seemingly no effect and then give it back immediately afterwards. I think he gives off eldritch horror vibes, but in a mostly benevolent way. If everyone else were ants, he would be an etymologist intrigued by our behavior or something.
How do you people feel about the Godot object and lifetime model? I found it hard to test my code because of how objects are tied to the tree, that emulating the tree isn't easy during testing, and that initialization during live use is different than if you instantiate manually, making it hard to rely on a constructor, since you might not be able to use it live.

I can't remember the exact details around this, since I only used Godot for a couple of jams and the last time was a year ago. But I was wondering if others have had the same reaction, perhaps this could be fixed? I love the engine in general, but this thing irked me.
> Comparing alphafold to conventional homology modeling is disingenuous at its most charitable interpretation.

It's really not - have you played around with AF at all? Made mutations to protein structures and asked it to model them? Go look up the crystal structures for important proteins like FOXA1 [1], AR [2], EWSR1 [3], etc (i.e. pretty much any protein target we really care about and haven't previously solved) and tell me with a straight face that AF has "solved" protein folding - it's just a fancy language model that's pattern matching to things it's already seen solved before.

signed, someone with a PhD in biochemistry.

[1] https://alphafold.ebi.ac.uk/entry/P55317
[2] https://alphafold.ebi.ac.uk/entry/P10275
[3] https://alphafold.ebi.ac.uk/entry/Q01844
I absolutley agree with you! I remember reacting badly seeing first movie in cinemas when they had left out Tom. I brought it up many times with friends that it was the biggest mistake to exclude him, but many argued he is not central to the story. I have never ever heard anyone dislike Tom.

I even read the Tom Bombadill songs child book.
This is the cold DM I tend to send:

"Hi [name]! I publish a newsletter with x+ subscribers that highlights the workspaces of creative individuals and would love to include you. Let me know if you're at all interested! :)"

I think the earliest guests simply liked the idea of the project and thought it would be fun to share the workspace that they spend hours of their day in.

Now I think people agree because they are able to plug their projects in front of thousands of readers.
Lemon scented napkins never smelt so good.

Edit:

Referring to HHGTTG:

https://www.bbc.co.uk/programmes/profiles/2sflZ6N9HJ144nxRqs...
The unemployment rate is also extremely low by historical standards, even when taking into account the various measures of unemployment. There is also plenty of evidence that businesses are finding it unusually difficult to hire employees. The Fed is probably fine with the unemployment rate rising pretty significantly because they probably don't see the current rate as being sustainable.
From what I can tell, the model DM built is mining subtle relationships between aligned columns of multiple sequence alignments and any structural information which is tangibly related to those sequences. Those relationships can be used to infer rough atomic distances ("this atom should be within 3 and 7 angstroms of this other atom"). A large matrix (partially filled out) of distances is output, and those distances are used as constraints in a force field (which also includes lots of prior knowledge about protein structure) and then they run simulations which attempt to minimize both the force field and constraint terms.

In principle you don't even need a physical force field- if you have enough distance information between pairs of atoms, you can derive a plausible structure by embedding the distances in R3 (https://en.wikipedia.org/wiki/Distance_geometry and https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.21...

Presumably, the signal they extract includes both rich local interactions (amino acids near in sequence) and distant ones inferred through sequence/structure relationships, and the constraints could in fact push a model towards a novel fold, presumably through some extremely subtle statistical relationships to other evolutionarily related proteins that adopt a different fold.
While what happened seems wrong based on the article, it's clearly not the "most vicious corporate counterattack in US history." No Pinkertons, no machine guns, no families.

At the end of the day (or house arrest) this is all still legal maneuvering. It may be vicious within that context but there are much bigger and sometimes nastier contexts out there.
Now recessions are racists then?
I don't, but regardless the US doesn't seem very close to direct democracy to me. So I disagree with OP when they say we're getting a glimpse of what direct democracy looks like right now.
So you were able to sue, for example Google or Qualtrics because a spammer sent you one of their links? I'm confused on that part. Or did the legit company reveal the identity of the spammer to you? Seems like the case would get tossed because the entity you're suing didn't send the spam? How did that part work? Thanks
2-10 spread went through the pre-GFC record of -28 bps a day or two ago.
Cirdan is certainly the oldest elf in Middle Earth during the period of the LotR. Treebeard and the other ents are probably older.
I had hoped ObjCs successor for app development would be something like FScript. Something that removed the footguns and unnecessary ceremony from ObjC but that had good interop with existing code.

Instead we got Swift, which ironically, given its uptake by external devs, I think was aimed at complaints from internal Apple users. Internal users at Apple were frustrated by how easy it was for external devs to introspect and modify private ObjC framework code. They also wanted performance features like value types and method inlining.

I don’t think many external app devs cared about those things, or to the extent they did C++ was an attractive option because a stable ABI doesn’t really matter internal to application code.

I continue to use ObjC for Mac and iOS dev because it’s a much simpler language than Swift, the system APIs I interact with are still implemented in ObjC, and C++ interop is easier via ObjC++. I suppose the day will come where I need something that is only accessible from Swift, and I’ll write Swift then, but for now Swift doesn’t solve any problems that I have.
ping and traceroute used to be very useful tools. Then for a period of time -- maybe still ongoing -- sysadmins and some network security folks decided that by blocking ALL ICMP at their network edge, they were increasing security. (Wrong!) As a result, you get hanging traceroutes with one or two hops left and you can't use ping to verify a host is online. Worse, blocking all ICMP breaks things like MTU discovery along the path. Recently I have seen admins coming to their senses and unblocking ICMP, but it's still an old rule-of-thumb held by many.
Almonds can be grown in Iowa, according to the document you cited, but in the next section (Which ones should I grow, or should I grow them all?) after your quote one finds:

"Almonds—Unreliable in bearing due to susceptibility to late frosts and numerous diseases"

So I would say no to commercial production of almonds on Iowa. The California central valley is probably the best place on Earth to grow almonds, so it's a good place to do that. The US needs to trade something for those Chinese goods. Deserts are good places to grow things, if you have the water, because the mentioned diseases are much less prone to develop and spread.
The Financial Times is relatively centrist in their coverage.
This is definitely not aimed at end users but aimed at advertising teams at companies that want to sell to end users.

Either way it’s totally something that came from a marketing budget not an engineering/ product budget… which is much smaller.
I found out, the hard way, about how the UK Rail system works.

Apparently, if a train is delayed, the owner is fined per hour.

This incentivizes cancellation. I assume the train was canceled. No idea why they let the passengers sleep through. That's weird.

This is an object lesson on unintended consequences.
every javascript discussion also ends up as a long series of ackchyually(ies)
Jack Ma to Give Up Control of Ant Group
It's all for naught if this is overlooked.
In 1974, President Ford had Whip Inflation Now buttons printed up, and 1981 was seven years later. So Volcker's dramatic raise was in that context. Whereas people are more used to a more moribund economy since 2008 with very low interest rates, inflation, and lots of QE, with the subprime bailout followed by the Covid stimulus. Actual non-negligible inflation and an actual interest rate is something people have started seeing more recently.
"Pizza is a savory food" is indeed a super basic fact.
That's not how Section 230 works: it's explicitly designed so that some editing does not open you to full liability for user provided content (but it's common to think it does the opposite). https://www.eff.org/deeplinks/2018/04/no-section-230-does-no... explains.
I too am in my late 30s and I've been writing Swift for 7 years now and the language itself is not buggy, at least anymore.

SwiftUI has it's issues and one is platform support. If you want to support anything before iOS 13 (even that has limited support) then you are out of luck. The only SwiftUI I have shipped is for WidgetKit and WatchOS, both being somewhat forced upon you.

While it can be cumbersome to do simple things in SwiftUI that were easy to do in UIKit, I haven't found too many bugs. Most issues I have run into are on the Xcode side.

If you work with any Apple platform it is worth pursuing. If you want to just learn and use Swift it does have decent support on Linux thanks to being able to bind with C libraries. Windows support is there, but is very much in its infancy.
>How is this topmost comment?

My guess would be that you're interpreting the comment as, "Please don't accidentally wander onto a film set out of ignorance," whereas my interpretation (and perhaps that of those who have voted for it) of the comment was, "Please don't be inspired by this to seek out and actively trespass on a closed film set."

They're two slightly different things.
How the fake diary ‘Go Ask Alice’ became a best seller
> Aliens receive a reply, which includes a map of their own world, including where their largest cities are located.

I think we'd interpret this as a threat, maybe, like a target map. They might too.

Probably best to reply with something more innocuous, like the Fibonacci sequence.
The phone itself appears to be a rebrand of the "Liberty Phone" from the last time around:

https://www.ghost.libertyblockchain.com

If you start the pre-order process, you'll start seeing links to unplugged-systems.com.

Interestingly, the "Liberty" branded site prominently claims "not made in China". I don't see a similar claim for the "Unplugged" branded version.
> an attorney can essentially sue you for free

Isn't his time essentially money?
> We might have got rid of the lead, but cadmium? Cobalt?

Last time I brought an oil palette and looked at the paints composition, the most toxic thing I could find was copper. And it was as colorful as any oil palette.
> have driven up the cost of fuel (which benefits them, an energy exporter),

Urals crude is trading $20-$30 below Brent, and China and India have Russia over a barrel when negotiating prices.
https://www.neste.com/investors/market-data/urals-brent-pric...

The war has not been going well for Russia at all, stagnant at best
https://understandingwar.org/project/ukraine-project

> is substantially richer

Russia has been putting out very cherry-picked data on their economy, which Western journalists have been taking at face value. They've been unable to make more PGMs, and their civilian sector is getting savaged.

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4167193

Perun's Youtube channel has been a great deep-dive source into the war economy in general. If you're at all interested in how governments acquire arms, he's an indispensable watch.
TL;DW: The time for Russia to win the war was February, now it's a matter of how many people and how much wrecked steel and how much of Ukraine he wants to make into a wasteland before he says uncle.

https://www.youtube.com/channel/UCC3ehuUksTyQ7bbjGntmx3Q

EDIT: Because I can't reply, Good Times Bad Times is good too. They're a bit more high-level and wider scope than Perun, and I'd recommend them as well.
People also move a lot more than they used to. That could be part of it. Who gives a shit if anyone else likes the kitchen color scheme that you love, if you're going to be in the house 20+ years? If you're only going to be in it 3-5 years, though....
I would not be commenting about how little interest I have in this story, if the website didn't break the back button. The people who do this, what are they thinking? That we will never leave, and keep watching their webpage until we die?

Tolkien is overrated, but this... this is useless and annoying.
It reads like racism to me.
Bleak, sad and probably true.
I think a much easier way would be if we just taxed phone calls at 1 cent each. I mean absolutely everything else is already taxed: you pay taxes just to stay alive. the least that could be done is add a 1 cent tax to each phone call, just enough to stop the mass phone calling.
If you spend a few minutes and get them on the phone and say "I want to wire you funds right now!", they will give you a bank account.
eric_cc & hacknat: Thanks for your posts; now I'm a bit sorry for complaining about bikeshedding comments. ;)
You will not, so long as the Senate exists, with the Supreme Court an additional firewall. This Constitution was written for slaveholders, giving them permanent power in the creation and structuring of the Senate. It was designed to serve the 0.1%, and does so admirably.
That is a hilarious security report.

1. They are selling a "secure" phone, but it only reviews their mobile apps.

2. They are testing their mobile apps according to the Open Web Application Security Project (OWASP) TOP 10. They are mobile apps, not web apps.

3. OWASP TOP 10 is advertised by OWASP as the "first step towards changing the software development culture within your organization into one that produces more secure code". Conformance does not mean security, it means the first step toward security.

It is like applying to a professorship in physics and your entire resume is that you once got a gold star on a elementary school arithmetic exam.
The expense was the labor!
Actually the article is asking whether a good but curtailed life is better than no life at all. Which is a more interesting question.
Show HN: Create real-human video from text in browser
Oh man if you think the BBC is even "moderate" than I have a bridge to sell you.
Old Tom Bombadil is a merry fellow.
So why add the destruction and suffering caused by animal agriculture on top of that?
Your conspiracy theory is laughable, primarily because "the current administration" doesn't have any control over the "official" marking of recessions, which is done by the National Bureau of Economic Research, which is a private, independent non-profit.
If they really had the legal right to exclude the blog author, then they also had the obligation to put up signs or barriers to exclude them.
Making camera sensor sizes less misleading
I remember I liked Gavin Nelson’s workspace. It was so minimal for a designer his caliber. I enjoyed Alex Cornell’s too.

If I may suggest, it would be cool to include screenshots of their workspace on both desktop and phone. But may be that is too much to ask from them. Anyway thank you for creating a refreshing newsletter!
I honestly don’t understand what were they thinking. Choose a random language’s random feature and swift has it. That’s hardly a good thing for a programming language, and it shows — there are some very nasty interactions between different features.
> The basic claim, to put it crudely at first, is that eating meat is morally good primarily because it benefits animals.

What is the definition benefit here? Would not being able to live freely, freely choose your food, choose your mate, choose (or chosen by nature) when you die, is benefit?

I'm usually right leaning, but in the issue of the environment, like clean energy and the meat industry, the wood industry, I'm left leaning.

Still not vegan yet though. Really hard to be vegan.

but overall I enjoyed the article.
true dat, there was an excellent series from one University going over that in details - changed my opinion on the matter - https://db.cs.cmu.edu/mmap-cidr2022/
That's a common and unimpressive argument around plant based diets. Short of suicide, is it a choice that causes the least possible harm? Surely it causes less suffering that farming all of those plants anyway, feeding them to other animals that take up more land and cause more pollution, and then killing those animals and eating them?
I'm not getting into the middle of the debate on whether or not this feature is good/bad, but I think this is a pretty easy question to answer.

There is now a feature that scans every photo you receive. There previously was not something scanning every photo you receive. What used to be a conversation between 2 people is now a conversation between 2 people and an Apple blackbox (assuming you turn the feature on).

As with most of these types of tech, the proponents of the "this involves erosion of privacy" aren't necessarily concerned with the exact implementation as described on release, but with how the blackbox works and how the blackbox (and the laws/regulations/obligations around it) will change in the future, and the inability to change the settings of the blackbox, effectively letting Apple become the touchstone for what is 'appropriate', even if it doesn't align with your view of 'appropriate'.
Fellow workspace design publisher here (https://officesnapshots.com) – Nice work!

I started a home office site ~13 years ago and wasn't able to ever make it happen so I am glad to hear that someone has cracked the code.