skysight-inc/HackerNews huggingface dataset:
This is probably one of the best applications of AI in science in terms of impact so far. I can't think of any other problem with the same potential impact.

EDIT: grammar
Oh man! Got heart attack too. Thank you for the update.
The press release reads like an absurdity. It's not the "protein universe", it's the "list of presumed globular proteins Google found and some inferences about their structure as given by their AI platform".

Proteins don't exist as crystals in a vacuum, that's just how humans solved the structure. Many of the non-globular proteins were solved using sequence manipulation or other tricks to get them to crystallize. Virtually all proteins exist to have their structures interact dynamically with the environment.

Google is simply supplying a list of what it presumes to be low RMSD models based on their tooling, for some sequences they found, and the tooling is based itself on data mostly from X-ray studies that may or may not have errors. Heck, we've barely even sequenced most of the DNA on this planet, and with methods like alternative splicing the transcriptome and hence proteome has to be many orders of magnitude larger than what we have knowledge of.

But sure, Google has solved the structure of the "protein universe", whatever that is.
Oh man! Got heart attack. Thank you for the update.
Group things logically vs just doing one huge docker-compose file or 500 individual things.

If you need 7 services together for that feature to work right, write them together. If you need 3 for the next one, group those.

If you at some point want to remove one, just bring down that docker-compose. That's it. Up to you to then backup/delete/leave as is.

You can write a script to automate when you start the machine. But you can also set things that are needed to autostart.
Here's an example of it being done (watch the video):

http://rgl.epfl.ch/publications/Vicini2022SDF
Temporarily freezing the funds is understandable, just long enough to ask for clarification or documentation from the merchant. Instead they decided to go the Google route of ignoring your customer because "algorithm said no".
Airshow: A Lightweight App for People Who Like Podcasts
It seems there are a pretty good deal of ideas for ever more sophisticated imaging technologies. That's nice. However it would be more reassuring to come up, at the same time (or in due course), with a similar supply of clever ideas for more sophisticated rocket engines, or, more likely, with a long series of fundamental contributions to our understanding of physics and biology. The ambition of the proposed mission is to reach a focal region ~548-900 AU away in order to image exoplanets which are distant up to 100 light years. I am sorry to have to remind us all about this, but given the extenuating long journey to reach a region that is not any closer than 548 AU, it would be even more "painful" to discover even more distant exoplanets which would remain beyond reach for all practical purposes – As per me discoveries of such level should remind us to reaffirm our commitment to take care of the only planet we can live for the foreseeable future.
You made the right choice to not say a word about it. Absolutely nothing good would have come from telling her.

And it's wonderful that you learned a lesson about the privacy of your children. I'm positive there are many parents who would have freaked out and gone further in violating their child's privacy and autonomy.
>8. The technology should provide a moat against every amateur trying to start a company. That’s why there are a million to-do list apps. That’s practically the first thing they teach in any course.

So you want to have a technology that's proofed against "every amateur trying to start a company" ... but you're a solo dev who thinks he's better than every other amateur trying to start a company?

This is also in direct conflict with your #2:
>2. It has to have a competition. Again, I want to make money, not be a pioneer.

Can't have it both ways
Nobody is talking about previous salary, the $3k/$5k thing was about yearly performance bonuses.
Exactly, I wish European mobile makers had adapted faster in the late 2000s.

We most likely wouldn't have to deal with the cyber moral police, and total lack of privacy we deal with now (which this is part of)
Did you mean arbitration?
To be honest, 89-92% sounds too optimistic for a real-world application.

But I was talking about applications of the lego assembly model. My intuition is that lego is a special case: the pieces are made to interlock with each other and there are only a small number of ways in which two pieces can lock together. Compare this with building a prefab house, for example, or a car, where elements must be bound together with nails, mortar, soldering, or glue etc, in essentially unpredictable ways.

I say that the approach described is pointless because I can't see any real-world applications of extracting assembly plans from a visualisation of an already-known assembly plan. Even less so when the object assembled is just a toy.

And it's been possible to assemble toys using machine vision, given a pre-determined set of instructions, from the 1970's already:

(Donald Michie presenting the Edinburgh Research Purpose General Assembly Robot, a.k.a. "Freddy"):

https://youtu.be/03p2CADwGF8?t=1668

More info of Freddy here

https://www.aiai.ed.ac.uk/project/freddy/

Freddy was tediously hand-programmed with a full plan but it used vision and touch to find the pieces of the toy it assembles in the video.
The bonuses where I am now are a % of the employee's base salary. A mid-level "meets" engineer can expect something like $20-25k during an average year for the company. Up to twice that for a strong year.
> But math is fiction […]

Anyone interested in this can search for "Is math invented or discovered?".
To me there's something about the use of color that can become a bit overwhelming. I think it's less about color, but the amount of color and contrast that appears in a given area—perceived busyness. It's difficult to describe. I think it's less about trying to stand out and more about people picking things that they like individually, but may not work well together.

It's kind of like going to get ice cream and having them put every topping on it. Gummy bears and mint chocolate chips taste good on their own and in various combinations with other things. Not so much when they are together.

As a designer I'm probably more sensitive when it comes to color though.
I work in open source and care deeply about it. Which is why having an organization that disregards reports of misconduct and at the same time frames itself to represent open source software is repugnant to me.

There's no doubt Stallman has contributed greatly to open source, but that does not excuse misconduct.
Next year will be closer to 0% than 15%, I wager. Let's see.

You say inflation is important when:

* you get a 30-year mortgage on a house. - true, but more inflation is better for you then.

* sign a 99-year lease. - true, but more inflation is better for you then.

* save money for retirement 45 years in the future. - that should not be in money, so the level of inflation is not relevant, real returns are (the difference between nominal returns and inflation).

* buy a life insurance policy that probably won't pay off for 50 years. - yes indeed. Some of them offer inflation protection.

* rent an apartment to someone under rent-control laws that can hold the rent fixed until they die. - yes indeed, good point. Also if you write a mortgage. That does not affect most average consumers, though.
Notes cover a lot of ground--from school lecture notes, reading notes, to something as simple as a todo list? Notes are writing, and writing has a purpose. I don't know what your purpose is, so I can only respond literally to your questions:

> "what kind of notes"

I take several kinds of 'notes'. I like to draw, so I have a sketch book. I have several different formats. Small notebook for drawing from life, including watercolor sketches. Medium size notebook for 'visual ideas' or organizational ideas (patterns of thought and their visualizations).

When I'm designing something I always use black pen & markers on letter size loose leaf paper. This way I can later scan these notes if something turns out to be very useful.

When I'm researching a philosophical topic I often make a text document for each book I'm reading. At the top goes a summary of the book and my interest. The next half are verbatim quotes. I find for my interest in philosophy a direct quote is more useful for my writing. I will follow the quote often with questions or my responses to those ideas. I also make a point of listing new words and their definitions if provided.

If I'm trying to learn a technical/programming topic the kinds of notes don't matter too much since I'm trying to get into code asap or something that I'm enabled to do by the research. Outlines are useful.

> "organizing your thought"

Not easily answered on the face of it, and highly dependent on the subject matter. If you asked me last month or next week I might have a different answer, but I think for me everything starts with a blank piece of paper and a pen and then becomes code or text files.

I'm not in school currently. Memorization for tests is not an objective, and so my methodologies reflect this fact. YMMV

Good luck.
What would you call it if I broke into your house, stole your TV and laptop, and told you "I'm just holding them, I'll return them someday, probably 240 days from now but maybe later".
> I said "offending", not "offensive".

Those are conjugates of the same word. What is your actual point?

> you just added an impartial characterization

Is it accurate or inaccurate characterization of TFA? Can we talk about that? Do you think I misunderstood what the author is trying to say?

> but it's not impartial

Yeah, I said up front that I'm biased against the "sacrifice the oldies for the sake of the economy" meme. I'm also biased against stupidity, which is to say that the author seems stupid to me.

> Here, let me play the same game

I'm not playing a game, and I know what I wrote.

> Mrs. X who refuses to get vaccinated...

I never mentioned getting or refusing to be vaccinated. That's all you.

> ...dies of Covid...

See, that's a euphemism. It's not a tidy, peaceful death. It's "dies in agony drowning in her own dissolving lung tissue" like I said. I'm not employing some rhetorical device, it's a simple plain English description of how Covid kills you.

> abysmal education for tens of millions of American school-aged children

Now there is something we could talk about.

But first let me point out that that's not what the author of the piece was saying. He wrote,

> But since most adults retain almost no academic knowledge, I’m skeptical of the long-term harm [of school closures]. Instead, I rest my case on the indubitable fact that in-person school provides invaluable daycare.

He's not talking about the harms that lockdowns did to children, in fact he discounts them. When I wrote "Young child misses two years of convenient daycare" I wasn't impartial, I'm describing the author's stance (which, as I said, is stupid IMO, I'm biased against it.) Your rewording misrepresents the author's argument.

- - - -

Anyhow, I personally have had a low opinion of public school ever since I was made to attend as a child. It seems to me that the US education system is a sick joke, and that "abysmal education for tens of millions of American school-aged children" is the norm anyway, long before the school closings. I think we should overhaul the whole system, and I while we're at it think we should look to making schools less of a disease vector. Covid won't be the last virus, eh?

If you want to argue about the state of the US school system, I'm "game" to do that. I got strong opinions and I'm willing to share.

If you want to argue about school closings vs. whatever I'm not your guy.

You may have heard of the recent San Francisco school board members recall? We threw out three of our top administrators. Just FYI, I voted to recall them, in part due to their poor handling of school re-opening. I hope that helps you understand that I'm not on "the other side"? We're all in this together. Humanity vs. the virus, eh?

Have a good day.

https://www.cnn.com/2022/02/16/politics/san-francisco-school...

P.S. Last but not least, God bless you and your kids and mom. I'm glad we talked this out. It's clear to me now that you are not one of these "mom should die so the kids can go back to school" folks and I really appreciate that. Take care, and well met.
Previous salary can’t affect future salary unless you let the previous salary be known.
>> Again: you somehow appear to have missed the point that this is a research project, not a SaaS proposal. It is not intended to have "real world usefulness", it's intended to advance the science of feature identification and image recognition. You know: science. You're a PhD student yourself, which makes it especially confusing that you appear to believe research has no value in its own right.

Your comment is aggressive and a personal attack, and for this reason I'm not engaging you further.
>I want to acquire customers by marketing rather than by sales

Hate to break it to you ... but marketing is sales, friend :)
> We should not exist per Occam.

We barely exist. Our history spans only a brief part of the Universe's history, we are confined to an infinitesimal bubble of all the space that is available. When we consider the Universe as a whole, Occam is correct. We are not even a rounding error.

But also: the Universe itself should not exist, per Occam. Yet it does. And we do. So let's work with that.
I'm not American in any way, not that it should matter. But I am an active maintainer of several open source projects.
cause as individual investors you can't force the company to build fabs. company will make money for investors in other ways.
Sure, and OP understands that. But, there’s apparently no effective resolution process, especially one involving a human.

What would you suggest the OP do to resolve their issue?
Suburbanites Fight over New Dinner Services in Mercedes Vans
I'd still be pissed even if they left a note saying that they would return the TV in four or more months.
Tree Sleuths: DNA is transforming the fight against illegal logging
It's a new tool, AlphaFool
>> Being exposed to this faux imagery of war messes with people's perception of war.

That seems true on the surface but I do not really buy it. Otherwise I believe that I would meet more people enamored by serial killer life after "Dexter" aired. But jokes aside I blame patriotism (and tribalism in general) for creation of this war hero myth. I can even give real life example - I'm from Poland and the ruling party is actively promoting so called cursed soldiers (żołnierze wyklęci) as a national symbol of fight with oppressor (former communist regime). And the way thay are doing it creates a very romantic image of what it means to be a soldier.
Yes banks regularly seize money from accounts for hundreds of days and refuse to discuss it with paying customers /s
"My fist is a point A and your face is at point B. If you're correct, my right hook will never connect with your nose. Would you like to empirically test your hypothesis?" :)
As someone coming from the physics side and not so much from the Computer graphics side of physically based rendering, I have high hopes for differentiable rendering as a general tool to extract knowledge from light-based measurements.

Most differentiable renderers stop at the object surface, but differentiable volumetric light transport is what would allow us to use the renderer to optimise a measurement device or for medical diagnostics or just to estimate the optical properties of a material (that is absorption and scattering coefficent and scattering phase function), which is a pretty hard problem in itself.

From a quick look, Mitsuba 3 seems to have everything in place to be used in such a setting and I'm really excited to see some use cases outside of Computer graphics.
I work with two companies developing true autonomous trucks and the conclusions in this article are dated and not accurate in light of the bigger picture.

1) The model most are working toward is "hub to hub" not point to point. As in, A human driver drives the truck from the warehouse or port to a hub on the highway outside the city surface streets. Then they get out of the truck and pick up another one that needs to go back into the city. The truck then drives itself on the highway to another hub near its destination where another human driver completes the trip. This works in multiple ways - it allows human drivers to deal with the hard part of automation while also avoiding the terrible away from home lifestyle, and it allows you to have dedicated autonomous trucks for on-highway separate from your human-driven fleet (you can swap the trailers instead of using the same cab). You'll see these hubs start cropping up in a couple years.

2) On-highway autonomy is not that far away anymore. It's definitely not a "next year" thing, but mid-late decade is a near certainty based on the current state of the tech. That's a long time for people used to software, but not a long time compared to the lifecycle of a truck.

3) There seems to be an implicit assumption in this write-up that autonomous systems will remain horribly expensive, which isn't true. They're expensive today because each generation of development is effectively custom built in small quantities. Just like Starsky said their camera system would drop in price with scale, a "ready for production" generation of autonomous driving kit in a few years will likely be close to 1/3 the current kit cost, which has very large impacts on the total ROI calculation.

I don't want to make it sound like there aren't big challenges left to solve - there are - but there's also a reason so much investment money has flowed into this space. The ROI does make sense, just not on the original hype-cycle timeline that a lot of people reported.
And that justify zero response to a business account by stripe? No, it doesn't. So stop with victim blaming and smear campaign
The solar system explorer view they have on that page is fantastic!

I recommend clicking on the "solar system" toggle in the bottom middle of the view. It gives you a real sense of the planets, probes, asteroids etc that are flying around our solar system.

Also reminds me of looking at air traffic control maps and what that might look like once intra-solar system space travel becomes routine.
For the life of me I thought this meant critical race theory...
Meteor predates Promises and Async/Await. You have to remember at the time all you had was callbacks and async.js to manage them. There was Bluebird around 2014 but Meteor was even before that. Meteor uses node-fiber, I assume it still does, but it was very "non-standard" at the time and definitely now. You rarely saw it in any codebase.
Remotely-driven trucks sounds terrifying.
First they freeze your assets earned via legitimate mutually beneficial contracts and supply during peace time. Then they start complaining that their homes in turn can get frozen too. So much for integrity.
You are correct, but the aim of the reddit post / this post is to get the problem solved. Billing is a complicated subject, and fraud is even more complicated.

A well placed, polite email to C-level staff often fixes the problem, but can draw attention to flaws in the support flow - or validate a customer-hostile standpoint, at which point you can make an informed decision about where to place your business.
Kind of ironic you want to "acquire customers by marketing rather than by sales" ... but have a Contact Sales page on your website (https://www.proxiesapi.com/contact-sales.php)
I was used to be a digital marketer of Alexa, but now the website was closed. I find another alternative one: Blexb.
> Surely the focal length and direction depends on the thing you want to look at?

Yes.

And "aiming" your observatory involves moving it on that sphere. Given the distances involved that is pretty much either impossible or time prohibitive.

The region starts at 548 AU from the Sun. So 548 times the average Sun-Earth distance.

In an ideal world you would teleport your camera to this location instantaneously, take a picture and then teleport to the next location to look at something else.

We don't know how to do that. The distances are immense.

So instead we pick a target, and send out a satellite or satellites on the opposite vector from it to take a peek. There is a single point where the target will be in perfect focus, but in practice (as the paper shows) the target is "in-focus" enough in a larger region that your satellites can take a picture while they fly through the region around the ideal point.
> Degraded battery packs?

Do car batteries not degrade? How are they different from other batteries?

> The "fuel tax" is more than made up for by all the many benefits of EV

From the government's perspective, it's lost cash flow.
2042: Earth receives a message from an alien intelligent species 32 light years away.

2109: Aliens receive a reply, which includes a map of their own world, including where their largest cities are located.

I'm just saying, this is totally a possibility! We can creep on the neighbours!
They compare the predicted structure (computed) to a known structure (physical x-ray crystallography). There's an annual competition CASP (Crtical Assessment of protein Structure Prediction) that does X-Ray crystallography on a protein. The identity of this protein is held secret by the organizers. Then research teams across the world present their models and attempt to predict without advance knowledge, the structure of the protein from their amino acid sequence. Think of CASP as a validation data set used to evaluate a machine learning model.

DeepMind crushes everyone else at this competition.
base = location
1st = velocity (location/time AKA speed)
2nd = acceleration (location/time/time AKA rate of change of speed)
3rd = jerk (location/time/time/time AKA rate of change of acceleration)

If you've ever rode in (or drove) a Model S P85D, P90D, P100D, Performance AWD, or Plaid, you'll understand "jerk".
I've needed linked list more often than enum to string over my 20+ years in industry. (both combined is less than a handful) This is mostly about what problems I've had to work on.

I think linked list taught me more useful skills than enum to string, even though I had to figure out the later on my own. Which is the important part of education, does learning things directly or indirectly help you more in the long run.
Funny because you sound like a guy that could claim crypto is an unregulated far west full or scammers, while trying to prove that seizing 100K at law enforcement request is the same as randomly keeping 3K of your customers funds.
I guess the argument then becomes one of scalability.