skysight-inc/HackerNews huggingface dataset:
"Genome" is used so loosely here (it always is in Science/Nature + Phylogeny papers), it's not the full totality of RNA/DNA in the organism the that is being compared. Similar sequences are aligned into "genes", with much data being excluded along the way. The repeatability of the overal analysis from start to finish is notoriously impossible, as there are so many parameters at different stages to keep track of, including versions of software used, etc. There is little to now appreciation/understanding of what CI, virtualization, etc. might add to this process yet, but it shoudl come. This isn't to say the methods are fundamentally flawed, it is to say we have long way to grow to truly incrementally build on the results of prior giants in a more robust way.

Long-branches, like the bird in question, happen in pretty much all clades of life from what I've seen. I suspect we will need a richer phylogentic model that takes into account things like epi-genetics, protein-folding, gene-rearangement etc. if we are to reach a higher level of resolution (or understanding) of the far-off-corners of the TOL.
Scheduling a vacation with family (kids) over Christmas, flying into New York City and using Airbnb is rolling the dice. Spend the extra few dollars for a hotel room and enjoy your vacation. You got what you were promised: a discount for an unstable experience and easy to use booking platform.
Also used to control drones and robots in other branches of the armed forces.
An attempt:

Adam sees a gold nugget on his property. He decides that rather than preserving plums like he normally does this time of year he will start a business mining gold. He takes out a loan from Bob at a high interest rate. He hires Charlie who previously worked as a tailor, and Dick who was unemployed.

Anticipating future riches Adam, Bob, Charlie and Dick all start spending more money. Evan the innkeeper has to cook more and fancier food for them. He works longer hours and builds up some savings, thinking that he will spend it on fine gold jewelry from Adam later.

The mining effort finds absolutely nothing. Adam has neither gold nor plums and defaults on his debt to Bob. He lays off Charlie and Dick. For Evan business goes back to normal, he has money but the jewelry he wanted to buy doesn't exist.

Eventually Adam starts preserving plums again and Charlie goes back to tailoring.
New construction slowing down isn't too much of a problem if the construction lasts longer and costs less to maintain.
I have followed that thread, and the Alzeimer "story" with great interest over the couple years I've been aware of it - in no way was my comment above meant to be a reflection on the possibility of a "taint" or lack-of scientific rigor (to bring in another example - the lack of repeatability in, oh, nearly every(?) social psychology experiment, etc. etc.) in the scientific and medical-science fields. The rise in administration at academic levels at the expense of science, the growing discontent in scientific funding being tied to results rather than curiousity, all very important - and very important to keep a skeptical mind about it all! Absolutely, that, to me, is the core of the scientific excercise.

I only meant that, in this particular case of polio detection, the cause and origin of the case is fairly cut-and-dry (there are other articles that have been published about it that give additional information), and introducing skepticism of the manner I responded to initially is likely to do more harm than good. Disinformation often begins with a distortion of a grain of truth, and the effects of that public skepticism and, dare I say it, ignorance (ironically?) breeds the environment that causes the reemergence of, for example, polio, amongst a public that is just being "skeptical" of vaccines.
Why would the platypus be a missing link to birds? Monotremes are rather obviously a very early mammalian offshoot, having retained significant original character (and a lot of weirdnesses) compared to therians.

And the platypus’ bill is convergent, if you look at a platypus skull it doesn’t look like a duck’s.
You’re welcome, happy to help.
If you are in the .NET space I suggest you to take a look at FusionCache. It has cache stampede protection built in, plus some other nice features like a fail-safe mechanism and soft/hard timeouts https://github.com/jodydonetti/ZiggyCreatures.FusionCache
TechEmpower Framework Benchmarks: Round 21
How can you identify a Domain-Driven Design Project?
I never thought about it that way, but for sysadmin questions if I see a DigitalOcean article I always pick it. They are always high quality and they version them by major OS version (Ubuntu 18/20/22).

Maybe that's why I have droplets, they got me by providing a good well priced service. /s
> talk values, not features

Be careful. I've seen lots of ads that try to convince me how valuable a certain product is; but the ad itself doesn't answer the "who, what, where, when, why, and how" that I need to know. So:

1: Make sure it's 100% clear what your product does (and doesn't) do.

2: Make sure that it's super-easy for me to find out high-level specifications. (For example, if you're selling a computer, it needs to be super-easy to find out what ports it has.)
Guards! Guards! is great, but the thing about Pratchett is that his writing got significantly better every few books until the very end of his life. Later entries in the series -- Night Watch and Thud! -- are much better.

As such, I'd recommend Going Postal as the entry point for the uninitiated.
Nobody can read minds and know exactly what Elon is thinking.

But I'd say that the elephant in the room that not even Elon can dive into too deeply is that the real issue is WHICH populations are declining. Nobody would voice any concern if suddenly Japanese people started humping like bunnies and their population was set to reach a billion in XX years.

The issue is that productive and educated people are not reproducing as much.

Unproductive and uneducated people with their hands out for aid are reproducing a lot.

The problem is that only one of these groups has a chance to get humanity to the stars.
Definitely shouldn't be considered "standard", the value judgement would be left to the inventor who decides whether or not to take it.
I'm not sure if arbitration would be considered a "legal proceeding" - it's a defined process that both parties agreed to upon entering into the agreement in the first place.

It's "legally binding", yes... but so is the initial contract.
How else can they location track you with location services disabled?
Had this experience w/ vrbo:

- support didn't offer to find a new last-minute place for our big group, but they did say they'd cover a new place

- basically 0% availability, so only $$$$ places left, and multiply that by a big group: 5-figure bill for lodging

- vrbo explicitly agreed to cover it after going through internal approvals, so we pulled the trigger. big event and clock was ticking before we'd be sleeping on the streets, so we were relieved.

- ... and then I got shafted with a 5-figure bill because, after-the-fact, they put up bureaucratic hurdles & denied our claim

After that shockingly fraudulent experience, I did some googling, and apparently this is common practices to all big players in this space. Multiple (winning) class action lawsuits.

On the plus side, better motivation for our business: we do gpu graph visualization & graph neural networks to help companies detect & prevent this kind of behavior based on all sorts of account metadata (transactions, image forensics, IPs, clickstreams) so personally motivated to help others target the bad guys causing problems for everyone else :)
Here's my OPML dump [0], if you care.

[0]: https://pastebin.com/NzZUT7aC
I have a couple pieces of code where we had to add rate limiting because it was just too easy to make too many async calls all at once, and things only got 'worse' as I fixed performance issues in the traversal code that were creating an ersatz backpressure situation.

Philosophically, the main problem is that promise caches are a primary enabler of the whole cache anti-pattern situation. People make the mistake of thinking that 'dynamic programming' means memoization and 'memoization' means caching. "Everything you said is wrong." Trying to explain this to people has been a recurring challenge, because it's such a common, shallow but strongly-held misunderstanding.

Youtube recently suggested this video to me, which does a pretty good job of explaining beginning and intermediate DP:

https://www.youtube.com/watch?v=oBt53YbR9Kk

What I love most about this video is that it introduces memoization about 10 minutes in, but by 20% of the way through it has already abandoned it for something better: tabulation. Tabulation is an interative traversal of the problem that gathers the important data not only in one place but within a single stack frame. It telegraphs a information architecture, while recursive calls represent emergent behavior. The reliance on cache to function not only obscures the information architecture, it does so by introducing global shared state. Global shared state and emergent behavior are both poison to the long-term health of a project, and here we have a single data structure that represents both in spades.

We are supposed to be fighting accidental coupling, and especially global variables, not engaging in word games to hide what we are doing.

So I think my answer to OP's question is 'tabulation', which is part data structure and part algorithm.
Yes, nsaids thin your blood and vadodilate dehydrated blood vessels in your head, this may also help reduce acetate toxins.

Caffeine as a mild stimulant then increases blood pressure and gives some adrenal pain relief (and was combined in Excedrin)

Alcohol (hair of the dog) also vasodilates and provides some pain relief.

Hydration is ultimately important.

Acetaminophen (Tylenol) should not be taken as it increases your liver load.

https://journals.plos.org/plosone/article?id=10.1371/journal...
OK, apology accepted. To address your url, I am not sure how the disastrous execution of the Berlin airport construction is a counterpoint to my claim that there is very little legal work going on here (and surely other EU countries) without detailed, written contracts.
Whoever was at least partly responsible for the Berlin problems was or will be sued, be penalised, and have to suffer the consequences of their mistakes or shortcomings. Because whoever worked on it had to sign binding contracts. This isn't the wild west, after all.
I read this in Cameron Tucker's voice.
No, there is absolutely nothing broken about symbolic links. What is the issue here is accessing user files as root. That is inherently unsafe in POSIX and also affects hardlinks as well (even more so, since you have to "follow" hardlinks http://michael.orlitzky.com/articles/posix_hardlink_heartach...).
The title is oversimplified clickbaity, and their actual finding is [from abstract], and my reaction below:

Our main conclusion is that for most of the more interesting consumer decisions, those that are “new” and non-habitual, prediction remains hard. In fact, in many cases, prediction has become harder due to the increasing influence of just-in-time information (user reviews, online recommendations, new options, etc.) at the point of decision that can neither be measured nor anticipated ex ante. Sophisticated methods and “big data” can in certain contexts improve predictions, but usually only slightly, and prediction remains very imprecise—so much so that it is often a waste of effort.

My initial reaction on skimming it is "savvy consumers are becoming increasingly desensitized to a sea of Facebook ads, Amazon fake reviews and rigged star ratings, undisclosed compensated influencers", aka the "unprecedented information environment" as the author describes things. I wouldn't call an Amazon review or FB ad/influencer post/affiliate link "information" as distinct to "this laptop has a rated battery life of 18h" or "this toaster comes in the following 5 color choices"; it's simply an influencing attempt; whether those contain any information (/misinformation), and whether users trust that they contain accurate information, seems to be something the study doesn't want to look into. Really the authors seem to be giving a very-judgment-free pass to anything calling itself "information".

Consider "unprecedented information environment" could also characterize the 2016 and 2020 US elections, 2016 UK Brexit referendum and 2022 Philippines election: "it is important to first understand how consumers make choices, particularly in the current information environment in which they have access to an unprecedented amount of information at the time they are making decisions." [obviously third-party political advertising is far less trustworthy than consumer advertising, but still].

What if the authors merely succeeded in proving that the rise in targeted influencing attempts has rendered the public more wary of targeted influencing attempts?
Earlier. In 1721 in Boston, a bomb was thrown at proponent of smallpox inoculation. There were far earlier methods than that, I assume they too faced witchcraft-like accusations and such.

https://sitn.hms.harvard.edu/flash/special-edition-on-infect...
See also this cppcon talk by Juan Pedro https://youtu.be/sPhpelUfu8Q
How can anyone plan their future if their work situation is so insecure, i.e. have a family, get a mortgage, etc.?
I can't confirm this from my experience over the last 8 years. Customer service was great from Airbnb.

Sometimes I prefer Airbnb, sometimes I prefer a hotel, it all depends on the kind of travel experience I'm looking for.
So someone who is able to install custom heatsinks on an expensive electronic is also going to be rendering long professional videos (to get it hot) and keep that +150F degree laptop on their lap long enough to cook their goods?

That sounds a little far fetched.
Some of the most intelligent, knowledgeable, respected-in-their-field distant family members of mine are like that. I've spent decade trying to figure it out, because selfishly it's terrifying and I don't want it happening to me.

One thing that seems to be common and is my working hypothesis, is that they're so smart and so respected in their field (or, in subset of cases, arrogant), that they simply trust themselves more than anybody else. There is nobody in their family and friends who can truly "slap some sense into them"; provide perspective, course-correct, nudge into objective reality or mainstream story, whatever we call it. I've actually asked a couple of them point blank - and they admitted, nope, there's nobody that they trust more than themselves. Couple of them even said - if you don't have trust and faith in yourself, you're weak.

So I'm hoping I'm somewhat inoculated against going off the deep end by having at least 3 people in my life (wife, sister, and one good friend) who can, and have, slapped some sense into me when I was going off the rails.
To clarify, I was asking if people who say "I love the smell of old books" really are window shoppers or if they actually do buy book in the parent commenter's experience.

I personal "enjoy" it in the sense that I associate it with used bookstores. I wouldn't want a candle scent of it in my room by any means.
Tesla strikes deal to have its own exclusive lane at US-Mexico border
Facebook Marketplace just plain doesn't work for me. I want to look at things in my area but it can't work out that 400 miles away in a different country is not "in my area", and I never ever ever want to see "Delivered to your door" Argos crap.
Elevated infection risk by later variants compared to Alpha in vaccinees
Agriculture is what got us into this trouble in the first place
Typical for republican congressmen, they only care about things that affected them personally. You see the same thing with republicans who suddenly have a child come out
I usually just take both, and even then, I sometimes wonder if they actually do anything or if it's just a mass scale placebo conspiracy.
> If you sell drugs like candy people will eat it like candy.

Even candy shouldn't be eaten like, well, candy.
Oh I do. I've gone to a number of games for every major team in my city (Chicago). I always have a good time. Some of that is because of the game, but I don't think it's surprising to say the people and environment are what makes a game fun to go to.
I still envy windows users for the easiness of downloading a single and being able to install a news software with a few clicks.

When I started using linux, my mind was blown away by how much better apt-get seemed. This continued until packages stopped being updated or when what I needed to install simply wasn't in my repos. This led to inclusion of "shady" repositories or compiling software myself which sometimes required compilation of dependencies which sometimes broke the system or even apt-get itself. In a few months installing new software and maintaining the system was more working the installing an updated version of my distro.

Today I try to use LTS distros and use flatpaks/snaps/AppImages as much as I can. I keep my system stable and my software up to date without one compromising another. My envy for how easier it is to install software on windows is much smaller today.
Tug 2022 Online – Presentations covering the TeX world
It's too bad Neil can't be persuaded to showrun a Discworld anthology series or something. The only video to really nail Discworld was Hogfather. (Going Postal had excellent casting but the script diverged way too far from the book.)
I understood both readings of my post and left it vague.

For instance: consider the plight of an all-white all-Muslim company who would face a possible lawsuit for not hiring a black guy who says he loves to eat well barbequed Southern-style pork in the office for lunch daily. Is hiring discrimination in this case racial, religious, dietary or “team fit”?

To me, any answer other than “it is none of your damn business why we hire anyone” is against the First Amendment’s assembly clause.
Your statement is simply statistically unlikely. If you really think "no one you know" uses those social media, then you should ask a statistically significant amount of people and verify, because perhaps you just think they don't use it while they actually do.
I wish the OP had shared conversion rate rather than overall sales. It's hard to say that 40% higher sales wasn't the result of something completely unrelated to the redesign.
They weren't tried in The Hague but they should have been. They got away with it.
I am not familiar with what 'extreme circumstances' would be to a practicing Anabaptist.

However, when a corporation as large as PayPal blatantly ignores a significant financial claim from a singular individual rendering the individual helpless, it seems a bit extreme.

In this case you can use the system the Corporation set up to suppress your ability to fight back against them.
You can link it to your IBAN, which lets you pay using SEPA Direct Debit. This is pretty useful if you don’t have or don’t want to use a credit card.
That provides value to the government which in turn provides value to its citizens. (theoretically, of course)
They make very inexpensive laptop fan pads that would completely prevent that from ever happening and add additional cooling to the laptop.
If the newer generation is OK with it then we're just going to be compost for the future that's ahead.
That's a shame. A high stress, high-knowledge job like that should pay accordingly.
TIL that ordering airstrikes on civilians specifically to murder civilians isn't a war crime.
This seems like treating a symptom and not the underlying cause.
Need to change your definition of God. Try: synonymous with logic and order in the universe and higher consciousness.
Kubefirst – GitOps Infrastructure and Application Delivery Platform
Gosh, that was written on page 21 of the wiki, if obly I had scrolled down to the footer notes.
> This was discontinued in the developed world, including the USA, a couple of decades ago after polio was eliminated there and the risk of spread from other countries was considered low enough.

Where are you getting this information from?

https://www.cdc.gov/nchs/fastats/immunize.htm
Clouded Judgement – Latest Trends in Cloud Software
Interesting, do you know if this extends to consumer technology companies like Lenovo and Motorola? I find the claim easy to believe about services like TikTok, but it seems like it would be more difficult to surveil hardware customers globally without being detected. On the other hand, if there were some backdoor in consumer hardware, I suppose we might not be able to detect it . . . .
> Not just 'not work', but 'actively repel'.

Anything connected to ads or marketing triggers a visceral response of disgust in me.

Not just towards products or companies that try to show me an ad, but for the advertising/marketing industry itself, the very concept of ads, and all the professions staffed with people who make it their life's work to promulgate it all. It reeks to me of hot air and lies.

Any I don't trust any company (looking at you, Google and Facebook) whose revenue comes primarily from ads - such income poisons everything it touches.
Its not because there is a series break when M1 was redefined in May 2020. See No.5: https://www.federalreserve.gov/releases/h6/h6_technical_qa.h...
At the risk of beating a dead horse, I think the tricky thing in evaluating comment voting is this: It's easy to look at a thread and see that junk comments were downvoted, and conclude it's working. It's harder to know which comments were never posted at all.
For anybody whom might be interested in "what a 4D cube might look like..."

https://youtu.be/1wAaI_6b9JE?t=2360

The entire video in mesmerizing -- one of the coolest party tricks I've learned is the double-twisted morbius strip dissection.
Until someone else comes up with a wild idea? I guess this is sort of what I had in mind, to make it at like state or industry sized scale, new idea comes along 20 companies try it. Spend a bunch of money hire people etc, feeding the economy. 16 companies fail. 1 company grows to 4x, 3 companies stay at 1x = 7x. 13 companies worth of value sort of has to dissolve into the economy before the next innovation/growth train comes along.
So here's how I attack these issues you've mentioned:

Extended Stay America. Almost every large city has one ("large" defined as more than 100,000 - 200,000 people). You can book for months at a time if necessary. They have WiFi at all locations, however...

I just donate to The Calyx Institute. My $750 pledge bought me a year of Sprint (now T-Mobile, and far more reliable) cellular access with a 5G WiFi hotspot and absolutely no data cap, ever. I ran 1.1 TiB through that access point one month and never had a moment's trouble. Long story short, Sprint bought Clearwire, Clearwire had a deal with the federal government to provide non-profits with cheap unlimited (actual unlimited) 4G / LTE hotspots and no fuckery (no slow-downs after X gigabytes transferred, no "preferred tier" customers like how MVNOs are second tier to the host provider). When Sprint bought Clearwire, the Feds only approved it with the provision Sprint had to honor the deal. Now that T-Mobile owns Sprint, they have to also honor the deal.
During COVID, we podded up with our son's best friend's family, husband and wife are both highly focused specialist doctors. One of them is an allergenist (hopefully I am spelling it right), a very straight up and no-nosnese person and I recall her telling us about a woman who showed up to her office about 9 months ago trying to get an allergenic exemption from vaccine so they could turn it in at work, as she wasn't going to be able to keep the job without it. He refused to provide it, because allergic reaction to the mRNA vaccine is not a thing, and it was doubly so for her.

They're both aghast that people would be refusing proven science. My wife and I share that, although hey, Darwin awards, take yourself out from the pool if you really want to do it. It's just too bad that their behavior impacts us too.