skysight-inc/HackerNews huggingface dataset:
I'm by no means an expert on this subject.

There are many different forms that RNA takes, and some of those forms are double-stranded, but differ from DNA in certain key ways. There are even "non-canonical" forms of DNA which exist whose nucleobases differ from the traditional four bases found in most DNA.

Thus, you're premise that all DNA on Earth is "chemically identical" is flawed. But, if you expand the scope of your a bit, then the answer is a little more satisfying.
VCs were pumping this hard. Journalists wouldn't have cared if Musk and other famous people weren't popping in during the initial hype phase.
I didn't say anything about breeder reactors.

In many jurisdictions, PUREX is routinely used to extract remaining fuel and chemically segregate the worst daughter products. A lot of the actinides can be burnt up in a normal reactor, like 239Pu.

Of course, in the long term, transmutation of LLFPs into precious metals is interesting, as is burning up more of the waste in e.g. fast reactors.
I fundamentally agree with you but I think a few things.

1. There's a small chance they fight because 10's of billions of dollars are at stake.

2. If they do fight I'm pretty sure they lose because I don't think a judge would want to force someone to do something they don't want to do like this, especially when that person is a billionaire.

3. It makes the future popcorn-eating amateur sports analysis in the future interesting(or less interesting?) on these kind of deals, because I think early on there was this sense that Elon Musk was taking this big risk by making a big offer and waving due diligence, and the reality is that risk doesn't work for billionaires the way it works for the rest of is. All this back and forth about the nuances of contract law end up irrelevant.
Your fundamental experiences as a human are already augmented by technologies so deeply integrated that our brains have changed to accommodate for them. For example: writing and speech.

What makes you think that "cyborg" means "foot replaced with hoverboard" and not things like "memory augmented with curated database" or "though process augmented with numeric-error-free calculation"?
Well he worked on it for 4 years (for fun?), so I'm not sure what you mean by walk away with a PhD. To me it seems like he has earned it, and even if he doesn't get one he obviously is able to
You might also enjoy the book if you enjoy conversation about rhetoric.
By the numbers, any kind of terrorism is an overblown boogeyman. Nuclear terrorism particularly so, and doubly overblown is nuclear terrorism that isn't state sponsored.
Exactly.

I've been a manager for a while and don't do much day to day hands on keyboard coding. I'm still able to help, sometimes quite a bit, but it depends on what the problem is.

If someone on the team is struggling with the gnarly domain specific application logic portions, I will usually direct them to a more senior teammate. I'm more likely to add confusion than reduce it. I'm not in those weeds enough to know how things are changing on a day to day basis. I understand the broad strokes, the roadmap, and where the senior devs are taking things. But I might not be able to tell a dev what the gotchas of their idea really are.

Where I find myself most effective is when I can leverage my experience as a developer in general. I can help them with pros and cons of technology X vs Y, pattern A vs B. I can point out things they might not have been aware of in terms of peculiarities of the tech stack and how it might change things - for instance bugs that are only clear if one understands the details of that standard library call. How to diagnose and debug a problem in an effective manner. How to research a problem.

tl;dr I can and do still talk code and help out my team. But the further one gets from being able to rely on my general experience instead of being embroiled in their day to day back and forth, the less effective I am at it
Nobody would put the smell of shit over a picture of anything. Electronic olfactory stimulation would cement marketing associations for children aged 0-12. If somebody ever figured out the technical side of delivering smells affordable and instantly, he/she would have subtle influence over people years after they are exposed to the initial entertainment product that built an association and memory in the child.
There's an audiobook of it which was pretty well done
Yep, I've burned out. I was doing a finance/business job that involved overseas travel and frequent 80+ hour weeks. I would sometimes not wash, eat or sleep in order to deliver. I fell for the same trap that lots of insecure overachievers fall for after college: a strong desire to prove myself, inability to set boundaries and a lack of mentorship / welfare support (other than to 'lean in').

After about 3 years of this, in 2019, I was away on a work trip and decided to tag a vacation on at the end. And I just couldn't get out of bed. I couldn't even bring myself to get food sent up to my room. I had already felt pretty suicidal by that point and knew I needed help, so I used work medical to set me up with a therapist.

It's taken way longer than I anticipated, and Covid didn't help, but I'm doing better. I'm far less neurotic, I actually have hobbies, and I've managed to hold down a couple of relationships for the first time in my life. To get to this stage, I needed to seriously take my foot of the pedal: I functionally went down to a part time job (same company, different position) and I had to completely reconfigure my values.

I miss my old self sometimes - the one that would crank all-nighters for work, a job offer or a side-hussle - but I know that old person wasn't going to last very long in the modern world!
I never used away messages on AIM - I'd just sign offline (AIM for the longest time didn't support offline messages) what I miss is being away conceptually.

I remember the time before everyone had cell phones, when I might be out all day (as a late teen, and a little older - I didn't get a mobile phone until 20), and I'd have a couple bucks in quarters if I needed to phone home (or anyone) and had my important phone numbers memorized. I also had a pager for a while, so if someone really needed me, they could page me, and I could call them back when I was near a phone.

When I was driving, I was away, on my bike? away, out for a walk? away - while I could check in with people if needed, I wasn't constantly reachable.

Now there are half a dozen ways anyone can reach me, at any time, and for a variety of cultural reasons, if I'm offline for more than a couple hours - I have people who will be concerned.
Low latency HLS is creating partial segments by bucketing 200ms of frames instead of 6s segments in standard HLS. Whereas in webrtc, the endpoint is sending the frame as soon as it is ready.

The apples apples comparison here is 0ms (in webrtc, no send side buffering) vs 200ms (in low latency HLS) or 6s (in standard HLS). This is independent of latency of the endpoint from CDN or source.

Another distinction is playback wait time, i.e., how quickly upon joining can it start rendering video.

I’m assuming the full reference picture (typically, an IFrame or a golden frame depending on the codec) in low latency HLS is only available at the start of each 6s segment and not in partial segments. So joining a live stream, the receiving endpoint would have to wait at most 6s before rendering.

Similarly in webrtc, it’s up to the system to generate a reference frame at regular intervals, as low as every second. Or to do it reactively, a receiving endpoint can ask the sender to send a new reference picture. This is done via a Full intra request, the wait time can be as quick as 1.5 times of the round trip time (as new codecs can generate a new iframe instantaneously upon receiving a request). There’s a slight cpu penalty for this which means that the sender getting too many full intra requests may typically throttle the response to 1s.

So Apples to Apples comparison for wait time would be up to 1s for webrtc vs 6s for HLS.
We've been looking at the logistics of co-location. Cloud Prices, even at Digital Ocean and Linode, are pricey!

The problem is finding anyone with experience doing this. It's a skillset that's sorta been lost.
No, they don't have to do anything except say, "We had a contract and you agreed to waive due diligence. Pay up."

EDIT: pay up in this context probably means $1 billion, though given that he is the world's richest man, it could conceivably include specific performance of the contract (meaning going through with the deal).
The article is about the SR-71 Blackbird. The new Top Gun features a plane based on the unreleased SR-72.
Not every country has 800m Euros, geologically stable areas and big chunks of land with no one living near by...
Why Crows Are as Smart as 7 Year Old Humans
Interestingly enough this was the last time I was being taught basic patent law at University!
I find this trends pretty well across generations - young people are rarely starting with "hello". I suspect people above a certain age just find doing it that way more polite
>The thesis is that while social Audio with proprietary recordings and time bound broadcasts failed, adding a social aspect to the fastgrowing podcasting space while retaining creator control and open formats will succeed.

And how is that theory proving up?
p5.js is quite good.

My biggest problem with Manim is the long feedback loop as you (last time i used it) have to render the animation to view it. But it is a really valuable tool.

With p5.js you can get an instant feedback loop and have the animation frame number available with a little effort.

I coded this up and someone shared it here:

https://news.ycombinator.com/item?id=31311463
> I was actually offered a position doing exactly that for a rather successful, nonFAANG valley company. Literally 'decide how to solve the problem, then hand it off and never think about it again.' It sounded awful for everyone involved.

I did that for a while, and it was exactly as awful as you would think. The implementers resented the implication that they couldn't do research and make interesting decisions, and I hated spending my time describing designs instead of implementing them. The design documents I wrote were DOA, since the implementers neglected to update them when they deviated from them. And of course all the normal dynamics of software development (shifting priorities, changing product requirements) were happening at the same time that I was handing off "finished" designs. It was a farce, and I quickly left for a role where I could be hands-on again.

The right way to support juniors is much more fluid, because different people need support in different areas, and you have to give them chances to stretch themselves as well as preventing them from coming under too much pressure.
Accused of stealing chip tech in US, now thriving in China
Probably not chemically identical, but similar. Different nucleotides and protein sequences, but you'd certainly see alot of the same structures (alpha helix, beta pleated sheet, etc.) and things like methylation. I would expect this based on the fact that DNA is incredibly information dense, so it would be surprising if the universe had completely novel ways to optimize for that problem.
ADHD here too. I find sometimes I need to engage in things that aren't what I am avoiding.

i.e. I want to go fishing but I have an assignment I have to do. Sometimes I just need to go fishing and once I get out there and relax (mentally decompress) I am finally hit with an overwhelming sense of not being able to fish but actually I wanna go do that thing I need to complete.

I am on the spectrum too (ASD) there is something with that + ADHD that makes this stuck-in-the-mud / "failure of executive function" so debilitating.

I fucking hate when people say this, but you're not alone. I see myself in your post.

1. Take a walk / try some meditation.
2. Go back to the assignment.
3. Get stuck / can't focus
4. Repeat step 1 till you can finish step 2.
Mostly streams about competitive programming, security, OS development, programming language development and game development.

Streamers in these categories come and go.

On Twitch you can find the developers of the zig and jai programming languages, the developers of Factorio, top competitors from codeforces, and all sort of interesting projects.

Ocassionally there are university professors, security researchers, etc.
Computing the matrix exponential is equivalent to finding the eigenvalues of a companion matrix, which in turn is equivalent to finding the roots of its characteristic polynomial. If you have nineteen ways of computing a matrix exponential, then you have nineteen ways to compute the roots of a polynomial, assuming that polynomial is the CP of the matrix you are exponentiating.
this is laudable.
Sure, Tesla's doing well, and despite an impressive production ramp supply is not meeting demand. So buying one will require getting lucky, paying top $, or preordering.

I would however suggest looking at total cost to own: including not just gas, but oil changes, maintenance, and even the gas and time spent getting to/from oil/gas/maintenance. I had a 2004 Subaru Forester and was surprised how much I was spending on gas, oil changes, and maintenance. Had a head gasket go and that was pretty expensive. So far the Tesla's been just purchase price, my home electricity rate (except for $50 ish of supercharging), and costs for a second set of tires at 30k miles.

Used cars do decreases costs, but if buying new the model 3 often wins comparisons on cost to own against Toyota Camry and Honda Accords.
Annihilating the eco system we life in demonstrates that our intelligence isn't that good, and doesn't seem to showcase it's a powerful force for long-term survival.
> "Because if they do anything Elon’s gonna threaten to make their lives miserable in many different ways."

> "this is an ugly tantrum"

I think you and OP are in agreement there.

But I'm highly interested what you think Elon would personally do to make the board's lives miserable. If anything, standing up to his tantrums gives them more "street cred", and if Elon does take over Twitter they will all immediately lose their "cushy job that pays well for little work" anyways.

If I'm a board member, extracting the $1 billion breakup fee from Musk without giving up any control of the company would be my number one strategy in saving my job, in defending my worth as a board member against Elon's charges of ineffectiveness, and in carrying out my fiduciary duty to shareholders.
"the first 100 year programming language" is definitely JavaScript. (If thinking in terms of Perl/Python like scripting and versatility, otherwise clearly C)
Judging by the fact that master lock is still widely sold, it’s not common knowledge how crap they are.
Hmm in those instances I think this would be much better solution: https://nixos.wiki/wiki/Nix-shell_shebang#Python

Instead of checking whether proper version is used, why not just ensure it runs on right now (and perhaps includes needed dependencies)
Agree, I typed up something similar (but less detailed) as a reference during my undergrad stats major. I'd expect a cookbook to have worked out examples of applications of these topics. But still looks very useful as a reference
I wouldn't consider this a good question because it changes with technology. Rather, ask about the factors that influence it.

You can have a 2x difference in main memory performance between machines these days.
I think you slightly misunderstood my point - I'm not arguing that we should or shouldn't built out a denser charging network. I'm just pointing out that from the standpoint of the consumer today, the fact that they can't hop in an electric and drive across country with the same lack of planning that they can with a gasoline vehicle is potentially significant.

Obviously many people are ok with that tradeoff, but it's likely that a much larger portion of the market will open up to electrics once consumers can essentially treat their electric as they would any other car.

I suspect that ultimately the solution will be a combination of many things working together: consumer education, longer range batteries, denser charging networks.
1998 was still very thoroughly the era when sysadmins were naming servers after characters and regions in Middle Earth. It was also the last time I read LOTR and The Hobbit (obviously read both multiple times - starting in 1988).

LOTR has always fallen into this odd middle place though, where lots of people had read it, or at least started reading it, but it was still considered pretty fringey. Only real spods like me got completely obsessed by it at school. Same with D&D: lots of people dabbled (including me), not many stuck. And D&D is still, I think, considered pretty nerdy, unlike perhaps LOTR.

The films - and the whole media and merchandising franchise that developed around them - really wrecked it all though: they weren't bad (in fact I enjoyed them) but LOTR and, later, The Hobbit was just everywhere for far too many years. Beyond that, they basically destroyed the imagery I had in my own mind of what Middle Earth was like. I can't say I'm particularly grateful.

I haven't read the books since. Partly that's because my tastes have changed and broadened, but it's also that the films somehow removed the appeal and motivation.

So I'd say the mainstreaming of LOTR really occurred with Peter Jackson's films meaning that, yes, Blind Guardian score high on nerdiness for creating albums around the books before this.
I just checked the median using my methodology and got 1.95 years. That's closer to your 1.7 than the mean of 2.7 I posted earlier.
Ask HN: Blog post about high-voltage electricity transmission / sub-station?
I'm looking for a blog post I saw on HN some years ago (maybe 3) about an underground electricity sub-station. It may be been couched as "what's that mysterious building" or somesuch, but it delved into high-voltage cables and how they need to be cooled with (flammable!) cooling oil. It was fascinating, and I'm keen to re-read it, but Google fails me. Hoping the poster is still around... and sees this before this question (rightly) gets taken down :-)
The author isn't confused, rather that is the point he is making.

Often schools teach you to only focus on the big O and ignore the constant multiplier. Those same schools then teach vectors and linked lists as the two main data structures. They talk about the cases where one has an obvious strength over the other, such as inserting into the middle, or using an index to access an element in the middle. However, they tend to skim over scenarios where the big O notation is the same but one has an advantage due to the constant multiplier, leading many students to come away with the impression that big O notation is all that matters.
Yeah, VC's that invested were propping it up, I saw this cycle repeat on there.

1. Some influential investor/entrepreneur/vs/elon musk type would tweet about the app.

2. The tweet would gain traction, news media would pick it up and write a story.

3. News articles were a sign that the app was "popular".

4. Everyone kept harping on about "installs".

Though it appeared that Clubhouse was going viral in popularity. It was really just a media echo chamber fueled by the "installs". People would hear about the app, install it and create an account, then play with it for 5 minutes before never opening the app again. But that mere install caused the cycle above to repeat.

In the end you had a ton of "installs", and barely any active users.
I have severe burnout, if you can call it that. I'm from Serbia, and I worked for an exploitative international affiliate marketing company for two years throughout the pandemic. I worked as a content editor, proofreading and editing an average of 5-10k words a day. Later I got "promoted" to site manager, which involved everything from kw research to posting content via WordPress. I also edited an average of 5-10k words daily.

The job payed $1k a month, and I didn't receive a single raise for two years, which is another reason why I quit. It was only after stopped working that I realized I was completely ruined, both mentally and physically.

The worst thing about this company is they use employee time trackers that analyze and store your mouse and keyboard movements and take screenshots every 10 minutes. My contract stated I had to have an activity level above 50% if I were to get paid.

Currently, I work as a writer for a digital marketing company, and I am having a hard time getting used to the lack of micromanagement and the slower (and much more normal) pace of work.

I can't afford rehabilitation, I must continue working to be able to survive which is really hard for me right now. I have some kind of PTSD too, I keep apologizing to everyone even though I haven't done anything wrong. So there you go... Sorry for the rant. :)
and maybe PS1?

Yeah it started on the PS1, as you say:

https://news.ycombinator.com/item?id=27699899
Anyone interested in this topic should check out Stephen Webb's book, "If the Universe Is Teeming with Aliens ... Where Is Everybody?".

It's not perfect, but it goes over a lot of possible explanations (75 different explanations!) for the Fermi Paradox. It covers pretty much every theory I've seen when people discuss the topic, aside from a government cover-up haha.

Simulations, aliens hiding on Earth, von Neumann probes, signals that we don't understand, distances being insurmountable, self-destructiveness, inescapable planets, singularities, it's got it all! A lot of the explanations ultimately can't get over the "OK, but surely there are at least a few exceptions" problem, but it's very fun to think about nonetheless. A really engrossing read if you like thinking about this stuff!

https://www.goodreads.com/en/book/show/180506.If_the_Univers...
I have severe burnout if you can call it that. I'm from Serbia, and worked for an exploitative international affiliate marketing company throughout the pandemic. I worked as a content editor and, later, site manager, having to do everything from research to posting content via WordPress.

The job payed $1k a month, and I didn't receive a single raise for two years, which is also the reason why I quit. It was after I'd working that I realized I was completely ruined, both mentally and physically.

The worst thing about this company is they use employee time trackers that analyze and store your mouse and keyboard movements, as well as take screenshots every 10 minutes. My contract stated I had to have an activity level above 50% if I were to get paid.

Currently, I work as a writer for a digital marketing company, and I am having a hard time getting used to the lack of micromanagement and the slower (and much more normal) pace of work. I can't afford rehabilitation, I must continue working to be able to survive which is really hard for me right now. I have some kind of PTSD too, I keep apologizing to everyone even though I haven't done anything wrong. So there you go... Sorry for the rant. :)
This one is interesting. I've never used a trackball mouse so I'm not sure how long it'd take for me to be productive. But I'll definitely try one at office to get a feel. Thanks for recommending this.
Post-scarcity socialism, luxury fully-automated space communism; whatever you call it, it's not hyper-capitalism.
"DNA" itself is so complicated that there are different conformations [1] of the winding, sense, rise, pucker, etc.

There are an unlimited number of different bases that could be used to encode information, too!

[1] https://en.wikipedia.org/wiki/A-DNA
No, this would normally be covered by a due diligence provision but Musk expressly chose not to include one in the agreement as an incentive to Twitter to approve the deal.

Twitter might let Musk off the hook for $1 billion, but he's paying something to get out of this.
Elon has just been thrashing with the reality he is on the hook for $1B due to this stupid idea.