skysight-inc/HackerNews huggingface dataset:
Startups depend on free flowing capital, i.e. excess liquidity, and so we tend to do more big moonshots during times of easy money, and there are lower rates of return elsewhere. When capital is tight, funds want to more direct ROI, and are less willing to shell out dollars for 'long term opportunities'. So companies doing '10 minute delivery' and need 10 years of 'losing money' to be profitable are in trouble.

Healthcare is an economy that tends to be much more recession proof, for a variety of reasons.

First is obviously less elastic demand - if your arm is broken, well, you need to fix it.

Second, is that it's really institutional and operational. Healthcare is not a highly leveraged industry, like Crypto - they're not subject so much to the whims of the market. Healthcare is not quite as 'capitalist' as other industries either, obviously in some ways it is, but there's an underlying kind of goodwill.

Third, is that 1/2 the industry is government spending, which doesn't get hit bad like markets, so there's a smoothing effect.

Fourth, is that investment cycles are much longer, to the point where they almost rise above most of the short term 5-10 year macro cycles.

Beyond that, there are indications that people 'get sick more' in downturns and there may be an increase in demand in some ways.

Healthcare tends to be a bit recession proof for those reasons. You may want to Google up on that a bit.
I worked on integrating a Nordic Bluetooth chip into a smartwatch, it was a nightmare. Some of the problems I encountered:

* the SDK kept changing, not just in minor ways but drastically. My suspicion was that this was so customers would hire Nordic to implement their drivers.

* The hardware kept changing. The chips would go out of production on the order of months or a year. Get your design working, go to order the parts, and the chips are no longer available (and the new chips use the new SDK so you have to rewrite the firmware).

* The Nordic API was nothing like the Bluetooth API, it was a wrapper around it, designed to make creating apps/drivers "simpler". But that means a lot of the Bluetooth documentation is useless to you, you have to translate it to the Nordic API. It also locks your software into one chip design.

* The firmware on the chip changes at will. There is no guarantee it will behave the same when you upgrade it. You only have access to the wrapper source code, not the source code of the stack that runs on the radio MCU.

I spent two years working on what should have been a project of a few months (I previously integrated an ANT+ radio with the smartwatch and it was dead simple.) One thought I had was that Bluetooth was designed to be a barrier to entry. It's become the default on phones and ANT+ doesn't have the market penetration, so if you can't make your gadget or phone support Bluetooth, your product is not marketable. The complexity is there to keep the smaller players out. The spec manuals are like 1500 pages long!

All of this means that many Bluetooth implementations and drivers are faulty because the developers can't spend the time to fully understand what they are doing. Larger companies can afford to hire the Nordic developers to write their drivers.
>traight into almost unbelievable amounts of incompetence

Have you seen the state of new reddit, of chat, of their video player, or literally any feature they've released in the past 4 years ?
I do not think that there is a one-size fits solution. People with kids might want to opt for six hour day, to better arrange life around them, some others might enjoy more the three day weekends.

Some people work on ships and work six months in twelve hour rotation and then be on vacation for six months.
On the other hand,

- support remote working

- have better housing closer to where people work

- if people want to commute an hour each way, that's on them
If HBS only manages 42% I imagine it's even less elsewhere. And that number includes life sciences, etc., that is way different.
Private Approximate Nearest Neighbor Search with Sublinear Communication [pdf]
When we were kids we'd go on vacation by loading the car on a train then sleeping on that very same train. I've got very fond memories of this. There were 2nd class cabins (for us) and 1st class ones (for my grandparents). My grandparents would treat us to the train's restaurant, which is like an actual restaurant and not some astronaut-like food served on your lap.

And when you arrive in the middle of nowhere, you have your own car and all your luggages. Beats flying and then taking a cab or renting a car big times.

Doesn't work across oceans though.
> No, you can bridge NFTs between chains.

Who is this "you"?

> No. They should query chain data directly. They need to setup an indexer and route any query through it.

Right. They "just have to query". They "just have to setup" something.

> You can attach attributes and state to NFT which can be replicated automatically between chains when someone bridges.

Who is this "you"? Who is this "someone"?

Again, the hand-wavy way crypto proponents approach this is maddening. And of course, there are exactly zero examples of this working in real life.
The thing about the 5 days a week is that at the weekends you end up doing personal stuff you neglected during the workdays.

I'm not sure that having two more hours a day will free up your weekend, I'm kind of leaning to 4 days a week because you can actually have useful time.

Personally, I wouldn't object to 3 days of non-stop working till the midnight to have 4 free days a week. Things won't pile up and instead of having just evenings, I will be able to leverage full days which will give me better freedom of movement away from where I live.

The 5 days a week schedule is my primary reason that I'm not in a full time job since a while. I was at home at 18:20 max, yet I never had time to do anything for myself.
Well, the justice department announced this yesterday which should allow harmless white hat behavior: https://www.justice.gov/opa/pr/department-justice-announces-...

But doing anything further is a bad idea imo.
I’d prefer to put up with mild annoyances than seep ever more into authoritarianism. Yes the guy is a dick, but you’re blowing it way out of proportion.

Honestly quite sick of the ever more sterile, dull, and gentrified cities we inhabit (I live in London).
The amount of critical thinking has plummeted and the amount of kneejerk judgement has exploded across the site in the last 5 years.
Reddit has become the kind of place it used to make fun of ten years ago.
It is little better than Twitter at this point, although my engagement with Twitter is limited, as I have never had an account there.
If you’re financially backing and providing direct hands on strategic guidance to an active and blatant scheme to commit securities fraud then you are doing something you should not be doing.

The previous sentence isn’t and shouldn’t be particularly controversial.
A major controversy at the the time, now forgotten in many places, that still has significant relevance today. The article does a good job of contextualizing a number of issues at the nexus of academic and healthcare problems in the US.

Reading it makes me think this issue is worth revisiting as a way of learning about contemporary problems in medicine and academics.

I had an experience of going from one place that responded to the crisis by selling a academic hospital to another place that chose not to. They both developed their own sets of issues related to the decisions, and in hindsight I think the decision to sell to corporations or not was a red herring, as the real problems were broader and more systemic.
Without knowing how a story-point is derived, it's not possible to conclude how much "work" this entails.
> Yes, there will likely always need to be some work done on the dev side to enable any of those use cases.

Not "likely". There will always be work to integrate.
Great point! We'll work on allowing people to select text.
> unlike PCs where they'll download just about anything on the internet

Google has that covered too with their "Google Safe Browsing" crap.
As a nerd with a good salary I find some suggestions here somewhat offensive.
That's the difference between suppressing/co-opting grass roots worker movements versus negotiating with them and incorporating some leverage through rights and regulations. The 40h 5d workweek was a radical demand not so long ago.
How so? This is just another example of the lengths people have to go to in order to counter the Kafkaesque nightmare of account closures.

The scandal is that those without means are fucked.
It's not lack of paper that's the limit here. It's how much you are able to see at once. Personally I feel like the notation is not the problem. However what is a problem is that mathematicians have a tendency to use notation without defining it (and mathematically notation is not as standardised as you might think).
Josephson Junction superconducting semiconductors are going to be graphene’s killer app.
IIRC in terms of cost, a cargo ship costs $0.01 per kg per km, a train costs $0.03 per kg per km, and an airplane costs $0.60 per kg per km. Assuming things which are environmental burdens are even a little bit correlated with costs, its not even a competition.
Broadly-neutralizing antibodies[1] which target non-variable sections of the virus are known - it does have a few conserved regions and the focus has generally been on hitting it there. The thing is, there are people who produce these types of antibodies and we know what they look like - but the trick is how to generate them successfully.

There's a whole fascinating set of interacting factors which HIV sits in a unique intersection of, but we are capable of building successful antibodies against it - it just takes years, which naturally we normally don't have (probably also some unique genetic factors).

[1] https://en.wikipedia.org/wiki/Broadly_neutralizing_HIV-1_ant...
This looks cool and I love the taxonomy and owning your own data.

But I wonder if you are trying to do too much. For example, why would I use Bach to transform my data instead of just doing it in my dbt project or wherever else I handle warehouse transforms?
OLED pixels take slightly longer to turn back on from fully off. I remember some VR headsets had trouble with this and they just set the minimum brightness to "1" instead of "0".

Edit: note this is per-subpixel, so you need to set some value in each color channel.
That doesn't answer the question. The ambiguity remains, and so does the question.
It's ridiculous ICE scooters are still allowed. They make more noise and cause more pollution than a 50 ton truck.
Gopher is also still functioning, technically.
I worked in the Netherlands. They had a 36 work week and asked me how I preferred to arrange those hours. I said: divide it by five please. Apparently I was the first person in their history (3k people work there! 100 years old institution) who asked for that! Everyone took either a day every two weeks off or worked 4x9hrs. A day every week or two is nice, of course, but I generally really like short days better! Doesn't leave me that exhausted and leaves a bit of time for things every day.
Why not both? 4 days, 6 hours each.

Hey employers reading this. Having a hard time finding software engineers? Offer me this and I will come running. I’ll be banging on your door with my resume. Think about it.
Not if the wood is glulam:

https://en.wikipedia.org/wiki/Glued_laminated_timber

Consider this picture:

https://en.wikipedia.org/wiki/Glued_laminated_timber#/media/...
Oh so that's why monitor makers are fighting the contrast wars...: websites using poor contrast text
What about fields with "," in them?
Whilst I sympathise, putting everything inline would have its problems. For example division symbols become much less clear and require parentheses. Exponentiation is easy to appreciate done in the math style. And so on.
Like the fact they are poor. .50 dollar a day won't feed your family.
But in return the overhead is immensely higher per invocation. Here [1] we see a 15 ns function call increase to nearly 1 us with tracing enabled. Given the implementation of dtrace which appears to patch in a user-kernel trap, introspect based on trap location, log, then return, this is very likely a representative overhead of every probe.

Incurring a 1 us overhead on each function call is very steep if you are doing a function entry/exit trace and nearly totally smears the profiling information you could get. In contrast, efficient recompilation-based instrumentation should only incur maybe 100 ns down to maybe around 10 ns depending on how aggressively you instrument and how much overhead you are willing to incur in the logging disabled case. In aggregate, a efficient recompilation-based approach should only incur a whole program overhead in the low double digit percent range when enabled and at most a low single-digit percent, if even that, when disabled. As a corollary, if 1/10th the per-invocation overhead results in say a aggregate 30% overhead, then we can reasonably assume the full overhead case is around 10x as much overhead resulting in 300% aggregate overhead, or a program taking 4x as long to run. That is a qualitatively different amount of overhead.

[1] http://dtrace.org/blogs/brendan/2011/02/18/dtrace-pid-provid...
Also what is the reason behind packing open-source project with UPX ?
https://github.com/lawl/NoiseTorch/issues/254#issuecomment-1...

Also this is very good example, why everyone should use VM for browsing internet, or better yet - different machine.
If you're popular enough, there alway be people who will use that $1mil RCE on you.
> Or is it bad to talk about such things around here?

Don't think if there is good reasoning and no name calling etc.

I would love to hear the explanation how these companies even got into YC from the people who picked them. Is this some type of divide between purely making money at YC (which can be dirty, immoral, bordering on criminal etc) and the tech community of HN who are generally against that sort of thing?

I mean it's not only crypto; it's dark patterns, privacy invasion etc; HN is generally against that, but probably many YC companies would be dead without them.

So is that the reason? YC!=HN?
I have no frigging clue why these biker jerks aren’t deafened by their own noise, when they manage to give me a start from a hundred yard away every single time.
I still have a launch-edition PS3 on firmware 1.01 that I got on launch day (wife and I were fortunate enough to be able to buy two and stash one). I've lost all kinds of stuff in moves and etc. since, but that thing will have to be pried from my cold dead hands.
Very good point.

(Excuse the smugness here, but I've wanglee a four day week WFH and my life is amazing)
> Opt in models?

Inflamatory post but this would actually mean managers would have to manage. You can't go to a seminar and cocktail party and come back with the insights to properly manage a team where people opt in to the model that works best for them.
It's by design to make flame wars harder to sustain
yeah you're right. I need to make it more clear. Going to work on that, thanks for the kind feedback :)
I've been working 32-hour weeks for the last year. I initially thought that I'd work 4 8-hour days a week, but quickly fell into a pattern of just working however long felt right. That ended up being 7 hours a day most days. On Thursdays I tally up how many hours I have left and work the remainder on Friday to finish out the week. I suspect I'm as productive as I would be at 40-hours a week.
Good. Removing loud bass systems from cars (even ones that come from the factory) ought to be next. People are entirely careless when it comes to the impact they make on others.
>I don't think that the number of git commits actually proves anything, other than I commit, code review, and merge code frequently. I wanted a better metric to quantify my feelings of alienation. I looked at Jira stories and story points. In my direct team of 10 people, myself included, I have completed 71% of all story points in 2022, the other 9 are responsible for the other 29%. That jives with my number of git commits compared to others as well.

You joke that you are a 10x dev but do you understand why? In fact doing the math... 71% vs 3% is more like 23x.

So you're a 23x dev. But it's not because you're 23x better than the average dev. You're 23x better than those devs. They achieve nothing and get away with it. Same pay either way. You are 23x against devs who are probably watching youtube, doomscrolling facebook, or playing video games.

>It feels like I don't have peers. I'm solely dragging my entire team and everyone else around me with me for the ride. This leads to stress, it feels that if I am not working on the "thing" it won't get completed.

You are lonely because everyone else isn't showing up to work. They are getting away with it because the managers also are doomscrolling facebook and playing video games.

If not for you holding shit together and getting abused someone would eventually ask why nobody is getting anything done.

You might be frustrated but any amount of holding back or trying to get this fixed will never work. You might think you can fix this situation but you cant.

The only option is to find a new job.
I believe you may have missed the joke, allow me to be clearer. I agree you must use text, but with those tags to allow that functionality (showing images and such), wouldn't it be better, or, hyper? A from of "hypertext" written in a markup language. Perhaps we should use an abbreviation to refer to it?
What issues did you guys run into?
I used to live on a pedestrian street used by skateboarders, also containing a glass recycling bin.

Emptying the glass bin was loud, but the noise lasted 5 seconds roughly once per week. I don't care about that.

The skateboarders were a very minor annoyance, and I accepted it as part of living in the centre of a city where there were very, very few residents. The sound was confined pretty much to that single street, unlike vehicle-type noises which seem to travel much further.
> prove you have the card

this is where blockchain is well suited. user can sign a message with their private key and cryptographically prove ownership where all other parties can also verify it cryptographically

> proxies are allowed in tournaments without proving anything

cool! but not what most refer to when talking about trading card games. if you have access to all cards in the game at any point there is no need to trade or do anything in particular to acquire and own a specific card except to say “I choose that.” if a game works like that it wouldn’t make sense to build blockchain based ownership around it.
Apollo is a really good mobile app for Reddit, but I expect Reddit will eventually buy it.

As for new users, it's likely a lot of people that reach Reddit from Google - their SEO seems to have gotten loads better in recent years. They also don't remember how simple oldreddit was, so they have no reference point.
That makes the most sense. With the sort of jobs I have, there's no way I could only work up to 6 hours per day without leaving something important undone.
> artist prints are routinely forged and resold. this is such a problem in high end artists work like Hirst that they must find complex ways to certify and authenticate their signed prints.

NFTs make this problem worse. E.g. OpenSea is awash with stolen art and removed the ability to contest the problem several months ago.
Or you could look at the absolutely factual statement that since Bitcoin isn’t a productive asset (in fact it’s the opposite it’s expensive to create) then every single dollar that will ever be taken out of Bitcoin is a dollar that some other person put in.

This is not true of normal investments. For example the dollars you get from selling McDonald’s stock 30 years after purchasing it come from people buying hamburgers.

The fact that there’s no such mechanism with Bitcoin demonstrates that it’s not actually an investment at all.

So when you get your profits out who will have given them to you, and what’s their story?
Thanks for sharing, I wasn't aware of that, that is a big news to me.
However I'm afraid this is very limited:
1) many peptides are produced by extracting them from cattle organs, here their thymus but see also cerebrolysin for example.
The Peptides researchers have often made synthetic analogues, which are similar to the endogenously produced version but can be produced in labs. However not every peptide has a synthetic variant and IIRC thymalin is derived from cattles thymuses.
Also what does produced by means of a technical process even means. Extraction from organs IS a technical process made of many reagents and steps.
A synthetic production of a chemical in a lab via enzymes is a mostly biological process in my book, please clarify EU.
2) > assuming that the compund was previously not known to be usable for a particular use case
Now that destroy most applications and its ridiculous.
What happen about a substance is that at first their is base public access research. This base research find most uses, here that thymalin increase lymphocite T production.
The goal of the base research is to enable future clinical trials years later.
However since this base research has found the use, it's no longer patentable and therefore ironically prevent clinical trials.
Now if applying an immunostimulant for X new immunosuppressive diseases is a separate patent despite deriving from the same basic public research property is valid.. is an open and ad-hoc question?

However to be perfectly honest, while my general statement about Peptides is true, there exists (unrelated to HIV) patents about thymalin I don't know how that is possible.
This blog post doesn't seem right to me. In the first part it says that the project is not an individual project anymore but the work of many. He then worries about the stability and maintenance of the project overtime in the long run. So as a result he makes the choice to create a language for fun to adress this issue instead of relying on an already existing stable and mature language. I fear that this decision will have the opposite desired effect on maintenability and contributions... I would have loved to see him being a little bit more open to other languages like Haxe, or D or go or any other language already stable and well maintened. It also impact the work of other contributors... But we will see how it plays out !
This is about the bay area specifically, where it's nigh-impossible to own a home if you weren't born into the landed gentry.
“Since few of the other commanders understood why Dragon Army was winning, they kept imitating the nonce tactics used in a particular battle instead of seeing the underlying method Ender used in training and organizing his army.”

--Ender's Shadow (voice of Bean)
This in Sydney please!! We vote in a few hours time... anybody supporting this get my vote
Jack Ma said 996 was a blessing.

Then he said other things that pissed off the wrong people and has not been seen since then.
If you lived in Brooklyn, you'll know the main source of noise is not these cars, it's groups of people blasting music on the street and barbecuing. They last for hours. When July comes, the main source of noise is people having fun with firecrackers. They are fired throughout the night for weeks.

So yeah, this is great, but the real noise sources are harder to address, because they involve approaching a whole group of people, not a lonely person in a car.
The Medical Power of Hypnosis
Pollution limits aren't authoritarianism. Toxic fumes and noise are both significant and harmful externalities, and the "free market" is really bad at curtailing externalities like these.

This might be dull and boring to you, but that's probably because these externalities do not significantly affect you. If you want to seek (loud and dangerous) thrills you have almost unlimited opportunities today to pursue them.