skysight-inc/HackerNews huggingface dataset:
"...As the only known intelligent civilization, human beings are always curious about the existence of other communicating extraterrestrial intelligent civilizations (CETIs). Based on the latest astrophysical information, we carry out Monte Carlo simulations to estimate the number of possible CETIs within our Galaxy and the
communication probability among them. Two poorly known parameters have a great impact on the results. One is the probability of life appearing on terrestrial planets and eventually evolving into a CETI (fc), and the other determines at what stage of their host star’s evolution CETIs would be born (F)..."

"...human beings need to survive 50 (+250 -49) Myr to receive one signal from other CETIs. Our results may quantitatively explain why we have not detected any alien signals so far. The uncertainty of the results has been discussed in detail and would be alleviated with the further improvement of our astronomical observation ability in the future..."
Tether is the de facto dollar. Hopefully most exchanges move off of it or at least have alternatives. I’m also wondering if it wouldn’t be the kind of catastrophe people were saying before
Thanks for this. There is a bit of tone deafness in this thread with everyone calling for fewer days of work so they can relax and then go to the cafe or linger over dinner while also wanting all those businesses to be open for them at all times. If we want to change the societal norms around working hours it has to include everyone, not just software developers or else it isn't going to stick.

Though honestly this thread is making me think that we need to basically reinvent the Sabbath. I'm old enough (mid 30s) to remember when most everything was closed on Sundays and now it's just another day for errands and brunch. Even holidays that were considered sacrosanct like Christmas and Thanksgiving you can now go to the store or they have absurd opening hours the day after (black friday) so that retail workers can't even enjoy the Holiday because they have a 4am shift the next day.
We're seriously out of whack here in the US.
I was not a fan of Gates when MS was the 800 pound gorilla in tech. Embrace, extend, extinguish was deplorable.

When he started on the Gates Foundation and became a philanthropist it helped reform him in my eyes. But the latest revelations have undone much of that.
> 1000 dollar per hour seems like a non-reasonable price

MRIs are expensive machinery that take highly-trained and well-paid technicians to maintain and operate. The imaging process takes an hour alone; start to finish, it's a two-hour process that is far from just pushing a button.

> one should have a legal right to command a MRI scan without paid analysis

I don't think there is a law, in America, prohibiting MRIs without expert analysis. But one, that's useless. And two, the people who don't think it's useless are the ones most likely to misinterpret the data and cause problems for the MRI provider.
Stablecoin Mechanisms and Use Cases
It's an interesting subject, with a long history; I think many of the biggest challenges are not technical.

The first commercially available AI/ML approach to breast cancer screening was available (US) in the late 90s. There have been many iterations and some improvements since, none of which really knock it out of the park but most clinical radiologists see the value. Perhaps the more interesting question then is why are people getting value out of uploading their own scans, i.e. why does their standard care path not already include this?
Though I think that private companies can choose who they do business with, I also think that these companies are an exception.

They are so huge they should probably be classified as a public utility of sorts. This is a tough pill to swallow for this site since it could possibly derail the tech gravy train.
I looked her up, she isn't my type. But if she's making it in this line of work, there obviously must be men who lust for her. Much uglier prostitutes than her don't have trouble finding interested men.
Yes, the word "only" is doing a lot of work in that sentence, and presumably the intent is for it to mean something like "culpably".
But there is no spin. There's either global thermonuclear war or there's nothing. If NATO isn't invading Russia, and Russia isn't invading NATO, then nothing has changed.

Does Russia want to start global thermonuclear war because they can argue a technicality that it's not their fault? No, I don't think so. They could start the war and the outcome would be the same at any time they want.

Excusing the edge case of a pathetic attempt of a land invasion of Finland or Poland or something crazy.
That has nothing to do with NAC. NAC supposedly helps protect against possible kidney damage caused by the contrast agent, nothing to do with radiation, ionizing or otherwise.

Doesn't seem to be a clear indication that it actually helps for that, but it's used for quite a lot of other things, like treating paracetamol overdose.
> There needs to be a direct challenge against this type of extra-judicial seizure in the US Supreme Court as it's a clear challenge to the entire operation of the rule of law and legal system.

There has been, and the Supreme Court upheld it. As I recall, they didn't even bother hearing the case.
Doesn’t sound like she actually stalked anyone. She’s using the term colloquially to mean “I spent time browsing a stranger’s social media profile”, which is a common usage.
OMG, yes.

The real tragedy there is that how to handle being challenged is a super important skill. And many of our best and brightest don't get to practice it all until it's too late. You can't learn a skill without practice. That's just not how it works.

It makes no sense to me at all that children from all different backgrounds and abilities go through an identical curriculum at an identical rate. Like, have the people that set that up never met humans and human children before?

My sister has the luxury of home-schooling her kids. And so they all have workbooks they can go through at their own individualized pace. As a result, one of them, my 6 year old nephew is now at about a 7th or 8th grade level in mathematics. He just loves doing math. Can you imagine how long that kid would have had to wait to actually be challenged in math if he went through the public school system? ...And they're actively trying to get rid of advanced study paths for such kids.
If it wasn't for the dangerous precedent, I probably wouldn't have a problem with this - it's definitely a bizarre transaction to me though.
https://news.ycombinator.com/item?id=17395675#17398314

Sorry if I'm being repetitive ^^^, but seeing the impact of civil forfeiture first-hand really shook me. I still get angry, and it took place 30 years ago!
I used to take noopept in my undergrad. No idea if it worked, or if I just started trying and that’s why I’m doing well now.

Recently I started to microdose shrooms. Anecdotally, I can juuust feel the ‘come-up’ ie light feeling in stomach and a wave of depersonalization, and while the effects on my cognition are minor, I feel that thinking is harder, but my intuition gets sharper.
This is great, and love that making apps like this is getting progressively easily.

Curious for your take on the recently-released https://github.com/Tensegritics/ClojureDart
A country where everything happens in slow motion and everyday interactions have unpredictable large fees.
It is safe to use, when used as _intended_ (ie how the car tells you every single time you turn autopilot on).

Cars are inherently unsafe when the driver is drunk, would you say cars are either safe or shouldn't exist and be illegal?
Apple's new headset launch pegged for 2023
Prostitution is legal in many places in Asia. Try not to paint a gigantic content with a single brushstroke.

As for the "Muslim world", I wouldn't be so sure that there's anything behind the sexual taboos held except garden variety discrimination. Monogamy is a sacred duty for women, but men are allowed to take up to 4 wives by Islamic law. Why can't women have 4 husbands?

Read Quran, Verse IV: 3. The best part is that if you can't be nice to your wives, just marry 4 slaves instead! That's a pretty serious endorsement that the roots of "taboos against sex work" are really just part and parcel of how men in ancient times maintained control over women.

Men get 4 wives, women get but one husband. Not only is it unfair, it's purely about keeping control over women. Or 4 women, for that matter.
Me to, however I forgave them after a great response video by Mathologer.
> 2015 - autonomous driving for highways and relatively simple roads

I don't think they achieved "autonomous" driving in any way, since they require the human driver to be paying attention.

> 2016 - S/X can drive autonomously with greater safety than a person - generally true

Really? I think this is an extraordinary claim given some of the crashes and near-crashes that have happened (and again, the "autonomous" word).
> For the month or so that it worked, it was pretty awesome. Unfortunately, that feeling didn't last more than maybe six weeks.

Sort of similar. I found every wrong road I took (supplements, diets, physical) helped - for 2 weeks and then never again. Stims turned out to be my right road.
Studies like this one are small steps forward, but the advance is surprisingly steady. Maybe people in a century will make fun of us brutes for not knowing how our brains worked.
Adderall?? That is medication... I thought nootropics was legal things like caffeine and l-theamine?
Presumably the patient can decline the biopsy? What happens to liability in that case? Does the doctor then have to decline to work with that patient further? What happens to liability if the doctor doesn't fire the patient? I agree there needs to be trust somehow, yet it seems practitioners hands are tied from a level above to toe the line for liability reasons rather than patient outcome. Is a doctor able to take into account all extenuating circumstances of a patient or only those predefined on a checklist passed on by a murky review process? What happens to patients who do research and find alternative (maybe better) opinions, well are they in network? Can a network have differing opinions among its practitioners?
I'm prob using the term wrong, it can be anywhere but in a small group or department it is exacerbated. With a large enough group it normally goes away.
So the user is waiting 30min and watches the progress bar?

What’s your frontend used for?
If the progress bar is everything then maybe you should just build a command line app.
Is the highway exit not a surface street?
I'm familiar with this testing strategy. It has one major upside: It allows an exam to test the material in great depth without being enormously long.

But it also has one major downside: Students may not learn all of the material equally well. If the random point in the material space that the exam focuses on happens to be a point that the student didn't learn as well, the exam result will appear as if the student learned all of the material poorly.

In other words, the exam has higher random variance.
Some people can sleep on such buses. I for sure can't. So I always prefer to go by bus over daytime (wasting a day) instead of the night (ruining both the night and the next day).
Finally! After many failed attempts at building local-first applications with CRDT, relationships is the hardest thing to deal with when it comes to CRDT. I think this tool has real potential and I would keep an eye on this.
Didn't expect to need to upgrade the mainboard so quickly :)

I prefer to wait for them to have an AMD option before changing out the mainboard.
That Time I Saved the VR Club
Russia is about to cut off Finland's natural gas
PBS eons is my favorite
I'm sorry to hear you're struggling. I've definitely been here a handful of times.

Hope and Help for your Nerves by Claire Weekes is the single best resource I have found for for learning to cope with Anxiety long term. I come back to it any time I find myself in similar patterns to what you describe.

Self compassion is another key coping tool. Being hard on yourself when you are in this state only makes things worse.

I highly recommend finding a therapist (I prefer ACT but traditional CBT is good too) and/or finding medication that works for you. The process of finding the right medication takes time, and cannot be rushed. Often, finding a Direct Primary Care provider trained in integrative medicine and is able to take the time to work with you as you are finding medication that works for you is a smoother path than going to the first psychiatrist you find on google IMO.

Just remember that everyone struggles like this at some point in their life. It is virtually unavoidable. Try to be kind to yourself in this time as you would a good friend. With patience and the right help, you will get past it.
A lot of the base images we ended up using are Debian so we just wanted to be consistent, whereas before we were running software from the RHEL repositories.
The Amazon referral link is suspicious, but I don't know anything about the author and they may very well be an unbiased critic simply trying to make some additional income from their blog.
I still don't buy that. In an office job you can find cost neutral ways to cut hours: a lot of people in this thread have said they would work harder in less time to achieve the same outcome, as a really simple example.

That's patently not an option in the service industry. You help people cut hours but now a restraunt, say, needs a percentage more staff (each of whom comes with a salary overhead) at a higher hourly wage.

This is before you consider the scale of it. About 85% of UK jobs are in the service sector. There is a massive labour shortage in key service areas anyway. At the same time, highly leveraged office workers cut their hours and have more leisure time, so service industry demands go up.

It's just not an easy pitch to make in my book. If I wanted to cut my hours I absolutely could come up with some automation and investment to help me do that, and my employer might agree to invest in that because I have high value and strong individual leverage.

That is just untrue for the vast majority of the service industry.
Thanks, I only discovered ClojureDart a few days ago and I'm planning on checking it out this weekend, sounds very promising!
I think Tether is the ultimate "Fake it till you make it" organization in crypto. Its kind of a joke now but everyone is in on the joke but it will probably end up being the defacto crypto parking place once things get real in crypto (e.g. you can buy a house with it) and the adults come in and shake out the current management.
That's your opinion. Any job could get boring after multiple decades.
Thanks for the pointer to that project, we'll take a look. =)

On your recommendation of Rust over C++, is the thought to deal with the double-bridging (platform-sdk => rust => libwebrtc) until webrtc.rs gets to a point where libwebrtc can be swapped out?
Only if you're traveling between Washington, DC and Orlando.
Sounds like the right decision - as anyone knows you're only supposed to teach "challenging authority" when the authority is one of the "accepted to challenge".
Some numbers for people interested in HIV:

Many countries in southern Africa have adult prevalence rates of >10% of HIV. In other parts of Africa most countries have a prevalence of ~1% or less. On other continents most countries have less than 1%, including the US with 0.3% adult prevalence. [1] For all the people wondering why this vaccine is being tested where it is, it's because just like we did for the covid vaccine, you split people up into placebo vs vaccine groups and then wait to see how many people get the virus from each group. If rates of HIV infection are as low as in the United States, you'd need to test the vaccine on ~100-1000x more people to see if it worked.

Non sequitur, but too interesting not to share: The estimated risk of acquiring HIV from a single sexual act is way lower than I realized until recently. Receptive vaginal sex with an infected individual is estimated to lead to infection only 8/10,000 times. Receptive anal sex is ~10-20 fold higher, 138/10,000. Sharing needles with an infected person is 63/10,000 [2]. That means you could have an ejaculates worth of HIV virions in your rectum, and be uninfected 49 times out of 50. (However, HIV infects immune cells, so it's way more likely to find an immune cell to infect if there are more in the area. That means infections or inflammation from other causes increase your risk of acquiring HIV compared to having no infection or inflammation. Similarly, way more target cells in blood, so if you have epithelial damage your risk goes up.)

[1] https://en.wikipedia.org/wiki/List_of_countries_by_HIV/AIDS_...

[2] https://www.cdc.gov/hiv/risk/estimates/riskbehaviors.html
Back in 2011 you could spend less than $20CAD and get enough noopept powder for months and months. Tastes like shit though (imagine the most bitter thing you’ve ever had x10) so I’d recommend shelling out more for gelcaps, or make them yourself.
The definition is super blurry now, and far from the original definition. Some people even consider microdosing shrooms or LSD as included.
The FDA is our most murderous bureaucracy.
A physics undergrad definitely includes most of the most damning experiments in physics. Muon capture for verifying Special Relativity, the photovoltaic and single-photon double slit experiment for Quantum, the spinning mirror thing for measuring the speed of light.

You definitely see enough that you don't need to take the models on faith.
Well I said X because it doesn't really matter. I'm very confident that my argument is true for X=100, and it's probably true for notably smaller numbers. I don't need exact statistics to know that it's much much less than 3.5 million.

And this isn't about a deep check for every single update, this is about deeper checking in case of blocks and bans, which happen at a much slower rate.
The specifics are worse than that!

It did little to make the cost of producing information cheaper; that still requires a human to analyze data, interview relevant people, and synthesize a useful article.

It did reduce the incremental cost of delivering that information to even closer to zero. Yes, serving a kilobyte of data is slightly cheaper than the paper and ink to put a thousand characters on a newspaper, but neither problem was actually all that expensive within living memory.

The major problem is that it increased the value of being that information provider to something significantly greater than the cost of distributing it. Reader attention and reader data can be sold for more than it costs to push a page to that reader, pushing the information content to the side and inverting the newspaper provider -> information consumer relationship into an attention selling consumer -> attention buying advertiser relationship, incentivizing clickbait, advertorials, and listicles. This new format is more economically powerful, and like an invasive species, it out-competes less greedy formats into extinction.
The reason I made this project 100% free and available to the general public is to help patients, especially in the remote area who has limited access to experienced radiologists for diagnosis, to at least get a second opinion on their mammogram. And I think this has certain value and this is why I'm doing this project.

Hao
So is it even possible to violate the 6th amendment? Could the police not just seize anything since that object has no rights?
It is one step closer to shutting the doors on Bitcoin as an isolated financial ecosystem. Bitcoin-to-actual-USD is a trackable / taxable event. Whales avoid it like the plague.

By moving to a pseudo-dollar like Tether, market makers can hang out while they wait for a suspect better buy-in price in the future. Should pseudo-dollars go way, they actual-Dollar transactions get a taxable haircut. Additionally, the friction of going from actual-Dollar to Bitcoin increases.

Tether is effectively behaving as a crypto-clearing house with their pseudo-dollar.
I use Frawk (https://github.com/ezrosent/frawk) a decent amount too! I downloaded it to do some parallel CSV processing and i've just kind of kept it ever since.
A paper record is superior in many ways but it has to live somewhere. You come to the hospital and they don't really remember you until your file burps up from the records department. You go to a different branch of your provider group and they have to mail the record to the branch before your appointment and mail it back, or fax the relevant information back and forth, allowing inconsistency to seep in.

It is also somewhat less likely in a well-managed EMR that you will have notes ending up in the wrong record.

Invoicing is also much simpler with an EMR. Good EMRs are able to keep track of charges as the medical record is updated with treatments and procedures.

Finally, EMRs enable very useful patient portals.

There are some aspects of EMRs that are particularly frustrating. They can be good at hiding useful information while displaying lots of unnecessary information. They seem to be developed by non-providers who are not really able to grok the way things work on the hospital floor. We spend a lot of money on upgrading computers and other devices, and yet they are not easily placed into a slot on the bed so that they can flow with the patient. Their validation rules often do not make sense, as mentioned in the article.

On net, I think that the EMRs are enabling better health care, but they have a long way to come.
The latest BMWs have a feature where you can have the cruise control speed automatically adjusted to be the current speed limit.

In the US, that is an almost universally useless feature. Standard freeway speed is 10 over the limit.
ripgrep isn't maintained now? That was fast :)

Or is it just done :)
Working factory is mind numbing in some ways but a lot of things that burn you out just don't exist: Politics, context switching, firefighting, changing priorities, working irregular hours to get project out of the door, meetings, Slack chats or phonecalls...

I love nonstop work, the problem is that a lot of times I have to unblock problems, stop to talk to other people, there are dependencies or things are on fire so a lot of time is spent busy waiting. It is work but it is not rewarding and you don't actually get much done.
Prepping for system design interviews so I can move to a different company.
Yeah, if you plan your appointment at a place 300km away willy nilly without checking the train schedule and if you plan your car drive in a way that you dont plan for any congestions leaving Hamburg, on the Autobahn, entering Berlin (good luck!), then yeah: The car is more expensive, more tiring, and slower. But get this: Instead of having an hour you can spend at your destination to your liking, you get to use that extra hour driving your car! Congratulations!

Sorry but that has to be the most contrived and ridicilous statement I've ever read. And this is coming from someone -- me -- who owns two cars, lives in Berlin and practically never uses public transportation.
This is a great point and something that we're actively working on improving in Mito. If you have millions of rows of data, its not enough to just scroll through your data, you need tools to build your understanding.

Some of the tools that you mentioned exist in Mito today. For example, Mito generates summary information about each column (all of the .describe() info along with a histogram of the data). And we're creating features for gaining a global understanding of the data too.

In practice, one of the main ways that we see people use Mito is for that initial exploration of the data. Often the first thing that users do when they import data into Mito is to correct the column dtype, delete columns that are irrelevant to their analysis, and filter out/replace missing values.