Taking your "Also" first:

The accelerations required for reasonably measurable Unruh temperatures will rip apart any structure we know of, so at present we only have hope for accelerating charged leptons. However even still we are probably only able to sustain the accelerations for on the order of nanoseconds, which poses seriously difficult engineering challenges to the detector-side of a measurement experiment.

That's the problem with Unruh radiation: acceleration has to be powered by something, and it's hard to separate the power source from the accelerated object. And if your object is accelerating strongly enough, it will pancake/disintegrate/explode. So we must use an outside power source, like in linear particle accelerators, to drive the extreme acceleration (at least many billions of billions of "g") of a particle that can survive it (or a stream of them), and try to work out the detection difficulties. This idea dates to J.S. Bell in 1983, who probably correctly summarized that the temperature changes would be "... too small for real experiments in linear accerators."

Wormholes in General Relativity are weird. They are not forbidden, but they make a mess of trying to extract good (as in compatible with everyday experience) behaviour from dust, gas, stars, and so forth populating the universe as we know it. Worse, once you allow them, it's hard to suppress them, and we can be pretty confident (by virtue of actually being alive and seeing a reliable relationship between a running engine and the fuel it consumes) that they are not popping up everywhere willy-nilly like they would without some unknown suppression mechanism.

In order to allow them in the first place, one needs some "exotic" matter (exotic in the sense of undiscovered, unknown, and very different from ordinary matter and even any plausible form of dark matter). Introducing that can give you wormholes, but then you have to be very careful about where and when you introduce the exotic stuff. Otherwise, wormholes everywhere, eating through ordinary matter structures. Depositing energy into discharged batteries, draining non-leaking fuel tanks. Or worse doing that in your cardiovascular system or brain. Also alien brains, stars, clouds of interstellar dust...

(Pervasive wormholes has been embraced by some name-brand theoreticians, but they then rely upon some unknown scale suppression mechanism: there are wormholes all over the place but they are always very very very tiny compared to atoms, so the effects on e.g. AAA-batteries and stars are undetectably small. In this approach you are already riddled with wormholes connecting subatomic bits of you to subatomic bits of e.g. our galaxy's central black hole, but alas, you remain unable to travel faster than light).

We can of course say, "well General Relativity could be wrong", and explore the consequences of a theory wherein we can build usefully-traversable wormholes without unknown matter. That theory, however, is virtually certain to be wrong on details about the orbits of bodies in our solar system and the difference at Earth-bound receivers from test signals sent across the solar system originating in our space probes like MESSENGER.