skysight-inc/HackerNews huggingface dataset:
"...An international study has found that patients given trastuzumab deruxtecan had an estimated overall survival rate of 94% after 12 months..."

"Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer":

https://www.nejm.org/doi/full/10.1056/nejmoa1914510
Because, like every other rage-bait article about healthcare in America, it's a blatant lie.

The article states in addition to the x-ray that "the bill included an abdominal CT scan, medication, and two nights in a hospital room". American hospitals are full of multimillion dollar equipment and trained specialists staffed around the clock.

"The full price" is a fiction relevant only to negotiation of actual price between providers and government/institutional payers, no individual ever pays that. It's an imaginary number used to start price discovery so that the hospital, insurance companies and critically the government medicare/medicaid program can make some set of concessions and discounts so that in the end everyone comes to a "win-win" agreement.
It's just not always true though, like in the case of "proper scoring rules". So it would seem at least theoretically possible to create a recommendation algorithm such that trying to "gamify it" would only increase the utility of its output.
There’s probably some sort of important lesson here…
So that you can cope with someone messing up a deployment and wanting to roll it back?

Let's say you avoid column restrictions in your db design, and you deploy some dodgy code that doesn't fill in a column correctly, now you've got heaps of dubious data cluttering your database, and apps failing because some precondition isn't being met. That doesn't sound like a good compromise to avoid headaches when updating a schema, does it?

So as ever, it's about making the right decisions on a case by case basis, and there is no 'one size fits all' for stuff like this.
I've recently started running unraid at home on an old desktop PC and it's really nice. I've also migrated my unifi controller, plex server and pihole to it and it's very easy. Way nicer than the previous setup where I had random dedicated devices each needing their own type of maintenance (unifi controller on my gaming pc needed me to download/install updates manually, plex server hardly received any updates running on old windows laptop and I was always worried about breaking it, and I almost never looked at the pihole running on a rpi).

Now I have a single dashboard and can upgrade each container with a single click, and everything stays on the happy path.
Do you think they'd ignore a court order?
When I worked on Fiber wifi and sat on the second floor (after it was renovated with a "movement" theme, but still kind of dungeony), David sat across the aisle from me. I didn't know who he was at first, and just thought of him as "perhaps the only extant person my parents' age who listened to the same music I did in middle school".

(And when Fiber's headcount got substantially cut and I needed to find a new team, I ended up working in "Kornistan", so named because the org was run by David's son Jeff.)
That's possible too, but I believe there's much more uncertainty about the fair market value of app store compared to out-of-band subscriptions.

Of course it would also be possible to do both, i.e. to mandate either a fixed rate or alternatively allowing out-of-band payments.
Top IPO banker in Moscow fears it will be decades before he sees another listing
As seen previously: there are more attractive targets, like skyscrapers.
Why wouldn't they? They haven't stopped writing and recording albums.
Show HN: I’ve made an RSS news-aggregator based on Wikipedia
This is my favorite HN thread in a while, already.

Although, thinking about how to explain these jokes to anyone else is difficult. I'll just leave my chuckling confined to my office.
It is hard.

First you need a purpose, a motivation. Not the kind you get on a sudden morning, but a visualization of how the end result is going to be. Because, the sudden motivations will go at the same speed it came to you. But many of these things needs a lifestyle change and lifestyle change needs consistency and for consistency you need to have something to hold on it.

Unless you have those "vision" to see yourself of, it is very hard to motivate yourself when you don't have results or if you're not motivated. Then again, many of these things I have heard in my early years but took the later half to figure out and settle on. So give it time, it will come.
> Nuclear fuel is cheap enough that it could be economical to simply [0] discard the unneeded production.

Just run wind turbines backwards, easy!
Its for "normies".
Ah, well, back in 2005 or so, Mac people were talking about launchd. Things have settled down since then.
Sort of off topic, but I really enjoyed the anecdote about why the source left Russia in the first place:

"Then the Russian government sent me some signals that it would be better for me to leave the country. I have a Web site, which my partner and I established back in 2000. It’s a Web site that monitors the activity of the Russian security services. And it used to have a media license, because in Russia you need to have a license to be in media. So, in the beginning of 2020, our Web site was stripped of its license. But the reason provided by the Russian censorship agency, which is in charge of these media licenses, was the death of [Agentura.ru’s] editor. And, because I’m the editor, I took it as a kind of perverse humor by the Russian censors. I got several signals of the same sort, enough that, in September of 2020, we decided to leave the country."
What's the latest research on the causes of these predispositions to addiction? Any gut bacteria link? Any gene that can be suppressed?
Alternatively, until that becomes available: https://sourcegraph.com.
Sending Data from Zapier to Segment with Webhooks
Issuing banks are generally not liable for card-not-present fraud, so it's essentially just extra work with little benfit to them.
It's been great. Very reliable on the hardware side, I've never had any issues with it, but it did take a while for me to get it set up properly.
Fertility rate is defined as number of children per woman [1]. Wether this is because of human choice or something else is irrelevant.

https://data.oecd.org/pop/fertility-rates.htm#:~:text=Fertil....
I really hope there will always be a map with reactors, so I can choose wisely a place of living. More reactors will mean more accidents.
SSH certificates are useful in large environments when scaling, automatic onboarding and offboarding are important, but IMO, small teams can (and should) continue using authorized key files as they have for years. They don't really need these features.
I’m old enough to remember when USB 1.x came out, and I was incredulous at the time that the standard type-A connector didn’t either (a) use an asymmetric shape like for example the D-sub connectors or (b) wasn’t reversible or coaxial like for example the TRRS connectors. It seemed so obviously stupid. The previously existing connectors that USB was intended to replace mostly didn’t have that problem.
You snipped off some context, though, that makes it a bit more reasonable. I think in this context the "tool" would be some sort of steganography-detection utility.

According to Brooks, the hidden dialog was placed in encrypted form at the end of the smiley bitmap file included with the operating system. Back in 1985, there weren't actually any tools that could discover this kind of extra data.
Outside of the joke - I'd say your own definition of prolific undermines you pretty hard there.

While I respect the author for the goal here, I would say he was neither abundantly inventive nor productive.

His inventiveness boiled down to taking an existing concept, and saving some disk space using an already known algorithm. To boot - his method of saving that space rendered the original intent (preventing copywrite of melodies) useless, and was already considered by the original group.

His productivity was a single morning's work, creating a single album, which is just random noise and will never be meaningfully listened to even a single time.

I'm not going to begrudge him the usage in the title, and I think it's a fun weekend project, but I also think it's pretty clearly clickbait (which is fine!).
Cut the BS. One part has been reported mass butchering newborns and pregnant women in hospitals. I hardly could think in anything more wrong than this.

There is not 'I can explain it' or 'this is not what it seems' or 'they must have a reason' or 'just kidding' here. This is not normal behavior in humans.

There is not any gray area about the war crimes of the Russian army. Had been videotaped, narrated, proven and reported extensively. Each building is a proof. And now they are talking about using chemical weapons to speed up this genocide. Seriously, what Russians were expecting? A clap?

Not taking sides? We are animals brain-wired to develop a strong reaction of seek and destroy in this cases. In less civilized times the murderers would be hunted and mashed to grinded meat.

Not more excuses. Don't call us kids, silly, ignorant, inconvenient or Russophobes. We are furious. We want this to stop. Right now.
None of this is hate against the citizens. No one wants to hurt the innocent people in Russia. But pulling out of Russia is about the only thing that anyone can do to slow the flow of money that will be used to fund the invasion of Ukraine.

The optimal thing would be to push the Russians out of Ukraine with military force, though that is also going to leave many dead. Just because they're soldiers doesn't mean they deserve death. But that's not an option anyway, because a NATO country joining the fight directly will cause World War 3. At best we end up with multiple countries from both sides joining the fight. At worst the nukes start flying.
I just don't understand what Western governments were thinking when they sanctioned Russian businesses.

"Hm, maybe if I put laws into the books that destroy the economy of a country and drives people in a certain geopolitical region into poverty, the countless innocent citizens that affected will realize what they did wrong! Wait, who am I actually targeting again?"

Oh wait.
I feel like USB-C is the moment when USB finally lives up to it's "universal" name. It's great. I can standardize on chargers and cables and be sure everything will just work. I just wish high-quality adapters were available so that I could do away with hubs and semi-permanently plug an adapter into the USB-A end of whatever special cable is needed. More advanced power supplies with more visibility and control would be nice too.
Counter-argument, written without informing the author: the risk of arguing without talking to the thesisholder is that you don't work with the iron man version of the thesis.

And straw man debate is a type of intellectual bullshit we have too much of already.

(So why am I engaging in this type of intellectual bullshit by writing this comment? Sometimes when I'm very tired and don't have energy to do more useful things like read a book I get a little kick out of trying to state arguments concisely and get little tokens of appreciation in the form of upvotes from fellow hackers.

These tokens are less likely in a drawn-out argument, even if it becomes intellectually more honest. So... I blame the system!)
And this seems to be completely lost today. Go listen to the Furtwrangler recordings, then listen to any modern arrangement. The modern arrangements are so precise, as if a computer is reading the scores. But the 1940s recordings are so full of life and vigor, it sounds like a different piece. And it is so much fun to listen to, even if the recording quality is atrocious by today's standards.

Karajan might have been the last of the conductors that I enjoy like listening to. His fifth changes pace but it feels so natural. The slow parts are drawn out were they need to be, but the fast parts just grab you and drag you along. There was no notation for that, it took interpretation. And he could get all the instruments to open the piece together. Even Berenbaum couldn't get his players to open the piece properly, at least not those that I could find on Youtube.

Thought there is one young guy on Youtube who does a terrific job conducting, I should go find that.
Yes - but this kinda gives it an easy pass. Makes it easier to ‘move fast and break things’ which isn’t always best
most people are selfish giant piles of shit. hard to find people worth befriending.
Median age very dramatically even between rural counties. Many counties in the rural southwest have a median age less than 37, probably due to a large number of immigrants [1]. For example, much of California - rural or urban - is very young (Even if the wealth is concentrated in the hands of older people). It's the same for Western Texas.

So their fate with respect to population decline is probably different than rural parts of Central Illinois or rural parts of the East and Midwest.

1. https://www.census.gov/library/visualizations/interactive/20...
Safe drinking water is not really much of an issue in the United States outside of lead pipes in mostly urban areas. If you have a well you know to get it checked every few years. Sometimes it needs to be treated. If you are really concerned you run your drinking water through a water filter. I grew up on a well that was hundreds of years old and only about 15 feet deep. And it is still a good well to this day. Modern wells are hundreds of feet deep and are sealed. They are very safe.

Access to healthcare is an issue depending on the area. There is zero financial incentive for healthcare workers to be in poor rural America. Really, though, it is a poverty issue. Rural areas, particularly those that were built around a specific and now defunct industry, such as coal mining, have a lack of available jobs and they are now unwilling to leave a town that no longer has a purpose to exist.
Nostalgia acts have always been a draw for families. Back in the 90’s the parents would bring the kids to see Crosby Stills and Nash, that sort of thing.
Worse, they incentivize "creators" to post "refrigerator door wisdom" type stuff optimized for likes or clicks or whatever (or outrage-bait, but that seems to be more in non-professional forums).
> If they can't afford it as a basic cost of doing business, they can always close.

Why do you choose such a company to do business with at the first place?

> Part of me thinks (perhaps naively) if I had the ability to speak with a real person over the phone, we could sort this out instead of constant emails or creating tickets that go into a black hole. As more companies outsource, automate, or severely cut their customer service department, there needs to be some kind of pressure to stop these frustrating experiences from happening.

Look at Dell or HP customer service. Google, Github or Digital ocean will become the same. Yes, you will never get the product designer or systems or devops engineer from those companies. The customer service will repeat the same thing million times over. (I lost Apple account, and unlike Google, I could reach Apple but they just repeated the same thing. (i.e) password is wrong; not our problem).

Also note that if there is direct connection to devops or dev, people ask silly questions to waste time. (i.e) These companies pay just $5000 per year to run their entire business with profits 100X and expect $10,000 per month DevOps will troubleshoot their problems.

> Voting with our dollars doesn't work when these companies are so integrated with our lives.

Example please. As long as it is not w e a p o n s all is wide open market.
Updated for clarification. The context was the overall responses to the study:

"In total, we received 43 responses. As not all questions were mandatory, the number of responses for a given question may be lower than the total number of participants"
Rookie mistake: SSH has no CRL, it has an KRL.

And its actually a separate thing since it operates largely independently from the CA.

I have one in place. Used it once to terminate access for someone.
Worldwide, religiosity is increasing despite declines in the west because of birth rates in Africa and Latin America and robust growth of Christianity in China: https://www.theguardian.com/news/2018/aug/27/religion-why-is.... There are now more Christians in China than there are people in Germany and Spain combined.
Let’s step back a little, please. This original context was about some BLM protests doing property damage, which included smashing storefronts and trash fires on the street.
GitLab team member here. Yes, you are correct.

We count the unique sum of users within a namespace which includes the users in the parent namespace (group), subgroups, and projects.

I created an MR to update the FAQ to make this more clear: https://gitlab.com/gitlab-com/www-gitlab-com/-/merge_request...

Thanks for the feedback.
Nasdaq Launches World’s First Index Family Focused on Carbon Removal
> They now need to get IT to distribute the public keys to a set of hosts, where the full list is possibly not known by any one person

If the team responsible for server security isn't able to identify all the servers they're responsible for, you've got far bigger problems than SSH certificates are going to solve.
How to work in other team’s codebases
Agreed! I like the idea of disclosure-based regulation: the onus is on the business to disclose relevant information (like no human support provided), and customers can choose accordingly.
https://cs.github.com and until that's publicly available: https://sourcegraph.com.
They don't handle the trades themselves. You use them to find a person and trade directly with them.
What a ridiculous article. People playing monopoly are greedy when they get rich on monopoly money? Mercedes drivers are less likely to stop at cross walks (never mind they are old and have no idea what they are doing)? Oh rich people don't agree with my political views, it must be because they are heartless (cough not because they have statistically higher IQs, no of course not).

How about we take some real examples. How much more likely is a poor person to murder someone? Beat their wife? ... you know the answer already, which of course was the point of these whole "rich people are antisocial" posts. It is attempt to try and subvert some inconvenient truths - truths that need to be subverted in order to push a certain ideology.

Anyway, from a personal note, I grew up in a very working class area, and I have been to many third world countries. Let me tell you, poverty, real poverty that is, really turns people into absolute pieces of shit. There is no judgment here, it would probably happen to me or anyone else reading this if they were in that situation, but poverty really ruins peoples morality and decency. That is a fact.
I agree that getting deep into the weeds on some of that stuff can be taxing on a smaller development team with a few senior generalists (of which I tend to be one) but I'm quite sure that companies at github scale have deep levels of performance expertise - still not always easy of course, because lots of these types of things only come up at some certain scale
GitLab seems to have been having their own set of issues this month. https://status.gitlab.com/pages/history/5b36dc6502d06804c083...
I used to host company stuff on a single physical server I built and put in the datacenter. After some time (and traffic overload) I redid and migrated the company stuff into the Kubernetes and cloud but I still kept the server for personal services and it is still running as we speak. I just had to switch one RAID drive on-line during all those years.. It is a bit costly, but hosts NextCloud photos, files, contacts, calendars, tasks there. Dovecot and Exim for native email, Roundcube webmail, LDAP and even authoritative Bind for couple of domains with a secondary replica on a VPS. Also gitolite git repo hosting, wireguard. I use those self-hosted services daily from android, my laptop and desktop. It is the real bare metal thing. It has some AppArmor policies, fail2ban, some docker containers too. Yes, it took a lot of time, configuration, constant small improvements, adding stuff one by one, DKIM, DMARC, DNSSEC, etc, it needs upgrades now and then but the hard part was mainly done at the beginning! Huge upfront cost and probably not for an ordinary hobbyist, true. But now the maintanence is quite ok. I can even SSH into it any time from Termux android terminal if I need to do something quick on the go or download something fast for backup via the server optical datalink. Most people were lazy, they decided to go clouds and cloud hosted services fast, they took shortcuts and now we have what we see today. There used to be a funny Microsoft tale ad [1] where a family was proud to have a server in the house. :xD While I am not a fan of Microsoft, this also inspired me to go this self-hosting (pain) way and learn a lot along the way. :)

[1] http://www.jimhaven.com/microsoft-stay-at-home-server
Very literally.

"We'll get a new front-end resource soon".
"We're opening two more backfills for backend resources".

"We need a front-end resource to unblock this ticket".

I have a interview on Monday which I will decline. Literally copy pasting from their meeting invite - "Request to panel-Please Take Resource Snapshot along with Any ID Proof and share the Feedback along with IRF post completion of interview."

It's gross.
As a less cynical take: When it comes to Ukraine support, the banner could theoretically have an anti-propoganda effect. Russian and Chinese citizens are cut off or pushed away from world political discourse in a lot of ways, so using open source libraries as a vector for anti-Russia messaging could have a real effect on devs in those countries.
> If you think Putin wouldn't use that to rally Russia and launch a massive war, you haven't observed Putin for long.

Do you believe that node-ipc would do this but the current vastly more impactful sanctions regime wont?

Also, everybody capable of thinking understands that Russia isn't capable of launching another "massive war" when it already has almost all of its conventional combat power committed to Ukraine.

If you think Putin would launch a nuclear war over wiper malware, you're an idiot. There's no other kind of "massive war" he could launch at this point.

> this software equivalent of a warcrime

Why not call it software holocaust if we're gonna go there? What's wrong with you?
Many of us run applications with more users, traffic, data, and/or features without having such a high frequency of outages.
I suppose it is something you just need to know. If you are looking at purchasing a home with a well have it inspected. Depending on where you live this may be a requirement for the sale of any home.
This is like asking why clicking buttons or links in web apps often just does nothing. You don't notice because you "know" the browser is loading the next page, you're waiting for the server and because you know that browsers don't bother displaying beachballs anymore even though the app is busy. But it's not actually any different.

If you like, structure your desktop app as two threads. One does the UI. The other does processing stuff. Exchange only messages back and forth. I've actually written a desktop app this way in the past. However it's not the silver bullet you might expect, largely because expectations users have for desktop apps are significantly higher than on a web app. In particular they expect something obvious to happen when they click buttons or menu items, and they definitely don't expect long delays simply because the backend is busy. So I ended up having to introduce some shared memory and read/write locks back again, as the pure message passing model was occasionally introducing UI stalls. In a web app you'd just ignore them because standards are low. On the desktop it's like on mobile, you have to care about the responsiveness a lot more.