skysight-inc/HackerNews huggingface dataset:
The next question, to my mind, is "How common is that cleavage site in other viruses, especially other viruses endemic to the origin location of SARS-Cov-2?" With a follow-up of "How possible would it be for multi-virus splicing to generate that sequence from two otherwise-unrelated, possibly damaged sequences ending up head-to-tail in the DNA of a host cell?"

We know of other novel viruses that have resulted from sequences of multiple viruses being spliced together in a living host naturally. I don't know how we'd disambiguate that possibility from human synthesis.
This is a little harder to do, but if you change your browser user-agent to something old (particularly IE10 or lower), you'll find that a lot more news sites have "lite" versions hiding behind content negotiation, rather than on a separate subdomain (particularly large news brands that would expect old users or business users in corporate environments where their browser choices may be limited).
Putin would pick another target, if he did start launching nukes. France has nuclear weapons.
Tangent: I wonder why, after having standards like ISO 8601 for decades, stuff like this is something we even have to think about. On a technical level, there's a need for exactly two date time formats: Monotonically increasing integer timestamps, and ISO 8601 style date time with timezones.
A list of lightweight websites without bloat
> It's limits on government power (regardless of what a majority want) and the ability for the people to kick out the current government that imo are most necessary for a free country. The other details don't really matter if you don't have these.

So a country where the people can't change their own government are what you call liberalism and democracy. Got it.
It was inevitable since 2014. The only thing that is surprising is that it took this long.
Building Infrastructure Platforms
Too pessimistic is a great, generous way, to summarize your biases which are those shared by most laypeople and even some self professed experts. Don’t try to turn wild fire into some stupid binary like everything else on tv, where you choose a side “pro-fire” or “anti-fire” and then insist that your way is the only one worthy of consideration.

Controlled burns, which it seem you favor, do not imply an absence of firefighting. It’s not “fire, good or bad?” Even though many seem to want to have that sort of debate. It’s an idiotic way of thinking.
The English can make an equally strong claim there and it's older. Parliamentary supremacy was quite established by the 1700s. While Parliament had a restricted franchise (as did the USA until the 20th century) it was an elected body with full powers.

Indeed, one of the major points of discontent was lack of parliamentary representation for the Americans despite nominally being equals -- kind of like the situation of Puerto Rico today.
This is not a case of a dictatorship pursing war against the interests of 90% the population. A lot of Russians support the separatists and are glad to see the military step in.

If you’re completely confused at why Putin is doing this and the best reason you can come up with is that he’s evil and stupid and just wants destruction, it’s only because you don’t understand the situation.
Very true - the other side to this is it's a _LOT_ harder to get to 200k+ in Europe than in California.

Anyway, I like the EU, but it still is a harder place to build wealth on the whole. Where I am you pay tax on _unrealized_ gains in ETF's (called deemed disposal), CGT is high (33%), and you get much less advantage saving for retirement than in the US.

On the other hand, if I lose my job, unemployment benefits more than cover our monthly expenses if we pare back a bit. Our overhead is low.

If it tells you anything I went back to California to start a company. Then, after someone drove a car in to my wife and the cop lied about her statement and she was lucky not to get a huge bill (it was the first few months of Obamacare before the horrific deductibles came in), AND she took her 1 week of vacation and that was it for the year, we decided to hell with that and moved back to the EU.
You might like to hear about John Mearsheimer's concept of "Liberal Hegemony" because it seems very similar to what you've been talking about.

Ten Minute Talk: https://www.youtube.com/watch?v=JDSK_Lb7xxI
Long Lecture: https://www.youtube.com/watch?v=ESwIVY2oimI
The propaganda, both in the west and in the east have made this matter very hard to understand for the average citizen.
What a terrible argument. A global energy supply system is a huge thing. That means it will make sense to spend literally trillions of dollars on it. This will mean building enormous capacity to build its components, including as many battery factories as we need.
Thanks. That's what I thought, good to see it's still possible.
I would be curious to know what is the nuclear latency of Ukraine, i.e. the technological distance from having a complete working device.

Ukraine operates 4 nuclear reactors and Soviet-era expertise on nuclear weapons is likely still present in the form of (retired) engineers and scientists, so they are likely able to develop it again.

This said, building a credible nuclear deterrence also requires at least one element of the nuclear triad, i.e. the capability to "deliver the gadget". In practical terms, more expertise to gain and more investments to do.
Why are the people against E2E get a 500K government grant FOR MARKETING and people towards E2E don't?
I hope not, because Ukraine borders several NATO countries, and we don't want that to spill over. So I hope the US won't fund insurgents, they can't win anyway.
Not for this version, but definitely for subsequent ones-- assuming we have the volumes to make AMD consider us.
Oh, ah, nice find, yeah, if you go down the URL:

https://www.math.utah.edu/~gustafso/s2017/2270/projects-2017...

Projects from a LA class at UofU.
The music probably isn't dictating the release date, but able to be completed alongside the critical path. I doubt that getting the music done will take much time from the devs who are focusing on the important things (I know its mostly just Tarn, but I beleive that there is actually a team working on the steam release, but may be wrong about that).
Clicking through to the source of the metric they used:

> A country is classified as an autocracy if it does not meet the above criteria of meaningful, free and fair, multi-party elections

https://ourworldindata.org/regimes-of-the-world-data

My guess is it may be to do with the difficulties that African Americans faced when voting.
Do you have a source regarding the suicide rate you can share?

Everything I'm finding suggests they went up (the CDC "morbidity and mortality weekly report" indicated a 22% spike in 2020 relative to 2019).
I don't know how they define democracy. Why France isn't in that list?
Really? What vehicles are being made today that use leaded gasoline and where are people buying it? I haven't seen a gas station selling leaded gas in decades now.
>Political leaders wanted

I feel the need to intervene here. The only thing political leaders want... is to get reelected. That is there job. To get reelected.

Sure, in certain cases, a politician has kids and wants their kids back in school. But in this example the line should go:

Political leaders had constituents that wanted kids back in school, so the leaders worked to make that happen.
Hey everyone,

It's Firat from Permify here. Me and my co-founders build because we live through how frustrating it is to build access control that lasts and give you piece of mind especially for Go Lang.

We have been building things over 5 years with my co-founders, and every time we get into authorizations it's just repetitive code as well as painful in terms thinking

- what users will nee

- what's the future reqs.

etc.

We had a commissioned project with a dozen of roles which both need ABAC & RBAC, and that's what makes us build Permify.

Permify is an plug-&-play API that helps you build ABAC & RBAC under 30mins. We have build Permify top on OPA. Which is an Open Source rule engine.

openpolicyagent.org

OPA has language called REGO. In times it's pretty hard navigate through, and get be master at.

So we make it crazy easy to right policies instead of using.

We have talk bunch of people about this, and we realize when you pass certain point even a small needs this.

For instance, it's not evident for small teams, and indies how useful this might be until they use it. But once they use it, they realized it's not a issue of prioritization since it almost take no time setup.

Right now, we have around 1200 devs signed up for our waitlist at permify.co

Me and my co-founder will be around to answer any question you have.
Could this be extended to include podcast ad-skipping? Being able to define A-B points and adding that to a blocklist would be amazing. I have several podcasts I've essentially stopped listening to because they're so consumed by ads.
If you wanted to have 2 redundant hosts, you could use something like GlusterFS for the replication. I have only tested it with XFS, but apparently it supports ZFS now: https://gluster-documentations.readthedocs.io/en/latest/Admi...
Touchy I think-- strictly strategically speaking you don't want to restrict Russian citizen access to non-Russian sources of information and social media.
NATO alliance members have NATO military bases, but you're right that US and NATO have no interest in adding Ukraine as a member. As we are seeing, the country is in a weak geographic position: Russia was able to stage forces to encircle >80% of the country prior to the invasion. Who would want that kind of ally?
And then the danger is from the world police.
It's the same advantage as, for example, letting ZFS manage your mountpoints: the pool itself contains all the configuration related to the file system, including NFS exports. It'll allow the export to be inherited to child datasets, removed when the file system is removed, change paths when the file system is renamed.

If you'd rather manage them the traditional way, that's there too (just as ZFS offers mountpoint=legacy if you want to use fstab).
They were governed by an autocracy during WWII. This is measuring the age of current democracies.
Not on Windows, with the exception of the Ribbon control in the File Explorer and Microsoft Office.
I haven't turned my camera on in months, but I get your point.
> How do other people deal with this?

"Thanks for your inquiry/PR/bug report. You can see the current development roadmap/backlog/issue tracker board here (link). If you would like me to prioritize your issue, please consider becoming a sponsor. If you want custom work, I can also offer consulting at the €X/day rate and I can provide a substantial discount if the product of the work is also released under a FOSS-license."
Fascinating that it is still in service. All of ours has been reclaimed for faster services and even 3g is starting to go away now.
Exactly. Haven't people learned from what's literally happening right now? Why wouldn't China taking over Taiwan be next if they see what's happening?
>USA missile defences in Arctic, and North Pacific can guarantee intercept a dozen uncoordinated launches, if what Raytheon says is true.

Russia has >6000 Nukes. If most were launched and missile defense systems have a 99% success rate that is still 10s of Nuclear strikes on the US Mainland. This would be the end of the US and likely irradiates large parts of North America...
He did write a new post. https://lt3000.blogspot.com/2022/02/russia-update-road-to-wa...
Aside; Cardinal, a VCV Rack wrapper, compiles in a bunch of modules, and a lot of care has being taken to avoid certain software and asset licences, partly so there are no problems with distros creating a binary package
https://github.com/DISTRHO/Cardinal/blob/main/docs/LICENSES....
Their economy is a little bit larger than the NY state economy.
> Russia is a waning power clinging to significance, not an ascending one.

I don't believe this, unless you define "significance" as nothing more than having your name in the world newspapers, even if it's for the wrong reasons.
People need to internalize that more. The gut-check reaction from most people is that process = overhead. It may be true that it creates that from time to time, but essentially a process should help align, remove confusion, maintain flow, and open up organizational capacity to do higher-level and more impactful work.
Just because you do not have universal suffrage does not make you an electoral democracy.

I would guess San Marino being on that list also, having been a republic (with elections, similar to the Roman republic) since the fourth century...
What Happened to Liveuamap.com?
https://liveuamap.com/ has been returning 500 errors since last night. Any idea what's going on?

This was an amazing resource - a map, updated in realtime with events in Ukraine as they unfold.
I cannot refute because it is true. You are not wrong.

Just ask them about the disaster in Afghanistan withdrawal and then they will realise the president who predicted that the Taliban would not do anything in 2021 was beyond incorrect.

Which then lead to this. Biden had no power to stop the Taliban and still has no power or guts to stop Putin.

Incredibly spineless, quite frankly.
As any newssian distributuon would predict: journalists fabricating stories to sell clicks.
Do you use a USB programmer, or did you buy ones that have a USB programmer built in?
They're such a nice starting place for embedded dev! I'd messed around with Arduino things for a long time, and recently started messing with the chip itself without the abstraction. The ATTINY series is powerful enough for many things while having a relatively small and easy to work with footprint (from a physical and register standpoint). It's actually possible to go through the entire datasheet and understand it, then poke all the right registers. It's also satisfying to be able to plop it onto a breadboard!

I'm excited for the Rust + AVR world to move forward a bit so I can keep playing with it without the currently required hacks :)
Yes. Also a lot of the intelligence is going to be coming over the same wires from civilians using social media and agents. Keeping the internet up is a priority.

Knocking an AS out here and there on the other hand for strategic reasons is a winner.
It's worth pointing out that the "genetic changes" in question are changes in gene expression.
Nazi occupation in half of it, puppet regime in the other half ( Vichy regime )
I assure you it was due to random chance (i got there after clicking "sita sings the blues" on the main page) and I didn't cherry pick that site. Possibly the tiny number of views was why it was so memorable though as something not gaining traction.
Seems to have been killed, there's just question marks everywhere there should be a dynamic value, and I can't interact with anything (Chrome for Android).

> ? in the room, click anywhere to turn the light ?

> click counter: ?
Tagging is work. Fiddly work that's surprisingly costly in effort if it's not trivially automatable stuff like time and date, location, application, and so on.

Naming is hard work, but tagging means creating and choosing shared names all the time, with the pressure that the combination needs to be reasonably unique, otherwise you won't find stuff.

Tagging is also fiddly if you don't have a really good bulk action UI. You can think of the user-controlled paths in a hierarchy as tags, and moving files is the action of untagging and tagging. By moving 100 files from one directory nested three/levels/deep to another, you are removing 300 "tags" and adding 300 different "tags". And you can rename the "tags". A single click and drag, 600 actions, and you can see the before and after trivially, and undo trivially too (at least in Windows).

Tagging is more useful for ad-hoc "favourite" lists, and the occasional cross-reference (but it's work to hunt down the elements in the xref).
While I don't doubt that bullying is tolerated in a lot of schools in the US, my son was recently physically bullied and the administration was very quick in setting up opportunities for natural intervention (doing so in a way that didn't single him out even further as weak or a snitch).

In addition, your statement that girls are being treated as expendable to promote male outcomes flies in the face of the clear evidence that the current US educational system favors girls over boys -- heavily by 8th grade (https://ed.stanford.edu/news/new-stanford-education-study-sh...). _Why_ this is happening is not super clear, but the current system is certainly not throwing girls under the bus to improve outcomes for boys.
I can’t have a reasonable conversation about this with someone who believes that the Russians are puppet masters pulling strings and setting narratives and that I’m just stupid for believing them.

The fact that Russia says it’s true is not a good reason why it cannot be true.

This has been going on for 8 years and we had peace and stable lines for the last 4. What changed?
That's already off the table:

https://www.reuters.com/world/europe/eu-launch-new-sanctions...
Ask HN: Remote Unix CLI on local files?
Tell me, if this idea is (1) useful, (2) possible or (3) already exists: A local command line tool that runs standard Unix CLI on a fully configured remote server but on local files.

So say the local machine only has a process called 'remo' that talks to a 'remo-server' process on a remote machine fully configured with git, gradle, python, java, etc. Then I could do something like this locally:

> remo git -clone https://github.com/user/MyProject

> cd MyProject

> remo gradle build

So with 'remo' I would be able to run all manner of CLI apps that read/write to the local file system without installing anything local. The two processes would be reasonably simple:

The local 'remo' CLI app does this:

- Open socket to 'remo-server' process on remote machine

- Execute remote CLI apps

- Vend file system info to 'remo-server' (LIST, HEAD, GET, PUT, DELETE)

The remote 'remo-server' process does this:

- Mount a virtual file system

- Execute processes locally in vfs root dir

- Feed vfs via communication with 'remo' process

I don't think this is a great business opportunity, and it's probably a little dangerous, but it seems like it could be pretty useful. What do you think?

jeff
I think he'd fold, say it's not the US's problem, and also reap a big (maybe justified) I-told-you-so about NATO's low defense spending.
Humans and hibernating mammals react to linoleic acid in the same way
You should use email and password stored in a password manager. If you put all your eggs in google don't be surprised when they delete your gmail account for no reason with no support for you to get it back.
Sorry to hear that man. It sounds like you’re young-ish. Time heals, even though it sucks right now, and life has a way of sending someone else down your way and you can make each other happy.. Best of luck friend
Yes, the compute pack has several DP outs and can be used without the headset.
Please explain why you think the West (Americans) ought to go die for Ukraine. If you want the west to go all in for this, I hope you've signed up to serve already.
> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance.

> “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and physical growth as well as your response to stress,”

Italics mine.

Linoleic acid is what induces torpor (hibernation) in mammals. We are mammals. People in the modern world are possibly something like half hibernating, inclusive of mental effects and of course the effect on difficult-to-remove-weight. The rise in Soybean oil consumption is an enormous change in the human diet over the last 50 years. The scale of it replacing so many fats, especially formerly animal fats, is just huge.

See: Humans and Hibernating Mammals React to The Same Amount of Dietary Linoleic Acid in the Same Way. By Becoming Torpid.

https://fireinabottle.net/humans-and-hibernating-mammals-rea...

(I submitted that article because I think its worth its own discussion: https://news.ycombinator.com/item?id=30456454)
The list of universal suffrage (all men, all women, all ethnicities) is different from the article too though. Only New Zealand in the 19th century. Followed closely by Finland, Norway, Denmark, etc.

Switzerland only required all cantons to allow women to vote in 1991. Australia only allowed all ethnicities to vote since 1967.

I agree the original article has a concept of democracy that is hard to understand when it says Australia and Switzerland were the only ones in the 19th century.

https://en.wikipedia.org/wiki/Universal_suffrage
You are most definitely not wrong. I would have expected some mention of the spectrum of a graph beyond simply defining what the eigenvalues are.

Incidentally, one interesting thing about the graph spectrum is that it's actually not a very interesting invariant. Among other things, almost all trees are cospectral, as proven in the following paper by Allen Schwenk in 1973: https://www.researchgate.net/publication/245264768_Almost_al...
Germany invaded Austria and Czechoslovakia just before WW2, and the allies didn't do much. Only when Germany invaded Poland did they declare war on Germany.
>The drama around it as portrayed in Western media is ridiculous. There won't be major loss of life nor any "war" in conventional sense. It would be no more war than it was in Crimea in 2014. I don't justify. It's a political disaster but not a humanitarian one.

Lay off the Vodka Sergei, there have already been airstrikes in a Dozen Ukrainian cities. The scale already far outpaces anything that happened in Crimea.
I used to believe the same things, that politicians followed the general will of their potential voters. I don't anymore, and reading some Chomsky made me understand how the system works. "Manufacturing Consent: The Political Economy of the Mass Media" is suggested reading, with the caveat that it opens the readers eyes to a harrowing reality and that what has been seen cannot be unseen.
Frankly I think a measurable chunk of Nvidia's success is that their GPU model names take much less effort to decipher than AMD's.
Instead EU will give some stern warnings.

And of course, they will also not block oligarchs and their families from going to EU, buying property there and using their banks.

If Russia is such a great country, why do all oligarchs children live and study in the West? Oh, because "we can't punish children for their parents sins". As if forbidding them to enter EU is "against human rights". Putin and the oligarchs are laughing on the floor now.
Could you elaborate on that? It doesn't surprise we that "genetic changes" is used sensationally, just would like to know what is actually happening and whether it's uncommon or something pretty normal?
Oh, that?

That's simply the strategy of Mad Men.

The problem is, he really is mad and has thousands of nukes.

The self induced detachment from reality like Angela Merkel suspected in 2014.
In reality a corrupt second class paranoid ward boss of a corrupt second class paranoid former major power.
With thousands of nukes.
And he probably thinks his time is running out to establish a Russian empire in his lifetime.
Despite thousands of nukes.

Do you recognize the repeating pattern above?
Thousands of nukes.

So yes, he will use nukes if there is no other option left.

There will be a Russian Empire or there will be nothing.
Your choice.

Pray some fraction from the Russian power apparatus eliminates him in time.
But I doubt, there is anyone left, not infected by the same illusion.
ST domestic pain and the risk the west loses its control of the global financial markets.