skysight-inc/HackerNews huggingface dataset:
The Autism Phenome Project has collected genetic data from all participants. Whole genome sequencing is starting to be processed. Getting funding was a bit tricky, somewhat surprisingly. The issue is N. We have a good sized cohort generally, but genetic analyses often require very large samples...mostly because individual genes only contribute small increases in risk for autism. Right now we are hoping to take a approach of looking for rare variants that have outsized effects.

Autism and Parkinson's: I had not known that. My grandmother also has Parkinson's. Thanks for the link. I will say that autism is a fairly new diagnosis, and thus not many with an autism diagnosis are old enough yet to get obvious Parkinson's. However, this and other aging topics WILL be a very hot topic of autism research in the next 20 years.

Thanks for the paper link. We think so too, at least in part. I point you to this paper [1], where we used Fear Potentiated Startle in Children With Autism: Association With Anxiety Symptoms and Amygdala VolumeWe have another paper that is under review that specifically looks at types of anxiety (DSM vs distinct anxiety) and amygdala development. Unfortunately, I don't have a shareable version yet.

[1] https://www.researchgate.net/publication/347985459_Fear_Pote... ]
Not that regulators might care but game software shapes how young people conceive of software and IP issues. A company notorious for manipulating IP buying out a massive game company means entire generations of children and families will be exposed to this software as a service model of IP consumption.
‘Nocebo effect’: two-thirds of Covid jab reactions not caused by vaccine
Thats funny. I've done some scrapers with unity and C#, since my experience comes from game dev. I thought I must have been doing it dumb ass way but nice there are to know there are some upsides to it as well.
The most famous Dutch cyclorama, the "Panorama Mesdag", depicting the Scheveningen beach, can be enjoyed with Dutch narrative at

https://www.q42.nl/werk/panorama-mesdag
That's a common sentiment when people see someone they happen to agree with getting moderated, but no - that's far from the case, and I can assure you the people with opposite views feel the same way. That is, they're just as sure that we're siding with your team. I assume it's no different with refs and sports.

https://news.ycombinator.com/item?id=26148870

https://hn.algolia.com/?dateRange=all&page=0&prefix=true&sor...
I knew a "business development" guy who specialized in these deals.

Unless something has changed drastically in this space, Dell isn't going anywhere near $200 plus the cost of a Windows license on every machine they sell.

I'm guessing they have higher return rates and higher support calls from people selecting the Linux option who don't fully understand what they're doing. If the Linux option reduced the price, there would be scores of people clicking it just to save a few bucks without understanding the consequences.

You have to keep in mind that technically competent people ordering laptops are actually a minority.
Yep, totally. I had some issues with Bluetooth coexistence on my Realtek WiFi card, tried installing various different drivers but nothing fixed it. Replaced it with an Intel one and it worked flawlessly.
I’m not sure Crypto.com is too worried about financial regulation or norms in their public statements. There is a widely used distinction between an “incident” and “breach” in the security community, and their public statements on this have been strange at best; certainly they are not reassuring.
this debian environment is news to me. thanks for that.
Just put a screen on a stand infront of your treadmill?
I think there is a pretty clear outcome, Intel will go fabless for highest end chips and continue as normal with everything else. They will have many customers (USG) who will require domestically manufactured chips. But they also need to compete with AMD, Apple, and friends and this will allow them to fab out to TSMC while, for lack of a better term, saving face.
Same here. Got 2TB on iCloud, and 2TB on Google. Main is iCloud, automatically synchronised. Backup is Google, kept synchronised as well. Got wife and children as authorised users on the first, and have managed credentials shared with them on the second.

Nothing lasts forever.
Visualization aesthetics bias trust in science, news, and social media
> Actually this is a very good question for engineers

What kind of engineers are you interviewing?

> I also like the question because even if you have no idea how GPS actually works, you could quickly come up with the rough idea yourself given that you have a bunch of satellites that can emit arbitrary signals.

I find this really doubtful. Someone who doesn’t already understand how GPS works is unlikely to derive it from first principals in a brief interview.
Legacy?

Organization and presenting information in a uniquely useful way can cement your life as having a major impact on the memetic evolution of human colossus, to a much greater degree than making babies ever will in most cases, even if no one ever knows or remembers your name.

There's a certain satisfaction in knowing that you've made an impact on millions of minds and that that impact will ripple into the future for as long as the light of consciousness burns.
Almost everyone <18 lies about their age on the internet. I have clicked through uncountably many age gates.
You can get that today by simply buying into one of the many low cost ETFs available following the S&P500 index. No need to wait for the State to do it for you.
in my case it's more often which audio, gamepad or graphics backend but yes, I actually had the log backend configuration request once ! (wanted to choose to log stuff in text files or websockets depending on the case, for a GUI app ; there was an explicit requirement that the entire software could be configured and used with only a mouse, no keyboard so many configuration menus were needed)
Hilarious take
I don't see anything about being "allowed to integrate with society" which would make it "cost neutral" for someone to immigrate to a country and begin drawing a UBI without any obligation to work for it. (Of course if one does have to work for it then it's not UBI; that's just a regular job.)
In that case I'd say that although the seed is random, the system is anything but random. This also goes for various forms of "chaos games". You make random choices on each turn, but those choices are within a framework of possible choices that winds up producing surprising order.
I'm not sure where you're getting those numbers, but your ranges are off by an OOM. Maybe if you're talking a lofted shot from high speed, high alt against a non-maneuvering target, with low PK expectations.
Stress doesn't scale with seniority. There are laid back positions out there at every level so downlevelling yourself seems pointless. Especially since there's a reasonable chance that you'll take a paycut and get nothing in return for it.
I have 3 layers:

Online: A big BTRFS "raid 1" (block-based mirroring) array. This is what Plex runs off of. If I lose a drive, I just replace it and rebalance. I run btrfs scrubs weekly.

Offline: I have a WD external hdd with a plain old ext4 hdd that I rsync all files to weekly. If my btrfs array shits itself, I just copy back over from this hdd.

Emergency: If the above process doesn't work (say: the external hdd is dead when I go to restore from it, or I can't physically find it, or my house floods and everything in the basement is lost, etc), then my fallback is:

I sync all truly critical stuff that can't be replaced (so, basically just family pics and videos) to S3 as deep archive storage class. Costs pennies. I don't do any fancy tar/archiving, encrypting, or compressing (since video and image files are generally already compressed). I figure the risk of people snooping at our family pics is smaller than the risk of me needing to restore from a backup and not being able to because of stupid reasons (lost gpg key, some kind of problem with tar, etc).

This is small, since most of my disk use is from things like rips I've made of BluRay/DVD's, FLACs from bandcamp or rips of music CD's, etc. Things I can recover with appropriate effort.
But it isn't easier to write something like this one in the "tweet storm" format. The author has to carefully consider how to divide the explanation up into separate tweets in a way that flows naturally.
They were available per https://en.wikipedia.org/wiki/Maytag#Maytag_International. The problem is that they didn't fit with typical requirements in a European home with their cost and space requirements. This relegated them to commercial usage or custom homes with dedicated space for a washer and drier.
This was not my specialty, but I think both.
Jeeze, I will stick with my modular solution: an ipad on a music stand. This is compatible not only with any commodity treadmill, but also bike trainers, ellipticals, and making vroomvroom noises on the motorcycle when it's too icy to actually ride. I could also swap out the ipad for a laptop, non-ipad tablet, or a collection of cute succulents should I desire it.

snark aside, I'm a bicycle guy and I really like that we have an ecosystem of bluetooth trainers and apps that all work pretty well with each other. Simulating hilly courses is actually really useful and has made me a better rider, so it's not like I'm advocating being a total luddite. While I prefer to ride outdoors in the sun, my area in Iowa is extremely flat and the only difficulty comes from the wind, and I find the new toys are a lot more fun than a dumb trainer with a sufferfest DVD. I don't really know much about the treadmill scene but I hope you guys have access to similar stuff.
> So it would be like domestic law enforcement (the FBI? state patrol?) using NSA-developed spyware, secretly, without court orders, against US citizens, including protestors.

In the US, we already have police using Stingray interceptors without warrants (and in a similar vein but less problematic, sweeping dragnet warrants issued to cell providers), which are slightly less invasive, but relatively comparable in terms of abuse potential.

https://www.aclu.org/issues/privacy-technology/surveillance-...
It just sounded like a good description. We never got any funding and started the business as a side project so no need for big words :)
A good starting point:

http://9p.io/sys/doc/ape.html

Note that this - as almost everything else that is plan 9 related - is dated.
My position is not balanced. I'm blind and vr is likely to start as an inaccessible technology. So, I'd say that it is just a noise to make people buy more useless stuff in a new package.

I could be wrong if people find it easier to use, to entertain, and make them productive. The last point is important, because if it is not making them money, people won't integrate it in their lives.
I'm just going by what the FDA said:

https://www.bizpacreview.com/2021/12/29/fda-says-rapid-at-ho...

“RADx recently performed preliminary studies evaluating the performance of some antigen tests using patient samples containing live virus, which represents the best way to evaluate true test performance in the short-term. Early data suggests that antigen tests do detect the omicron variant but may have reduced sensitivity,” according to the FDA.
My take is more that the framing of maximizing an externally provided reward describing a single task only helps an agent who can rely on the rules of that task remaining fixed. Humans don't just try to do one task well; we switch between tasks. We don't have episodes that reset really; we have one long episode, and our actions decades ago can have bearing on our well-being today. What is a good state or a good policy varies substantially over time. The concept of the value of a state or (state, action) is ambiguous, because who knows what you'll want tomorrow? If the definition of value shifts, but the rules of the world don't, then a modeling becomes more "valuable".
they’re not going to unionize

This assumes we keep them just complex enough for the job. If computer scientists and developers make Bender too smart or cloud connect them, they may decide to hold a union vote. There was a trial in the science fiction show Star Trek the Next Generation to decide if Lt. Commander Data an android had rights and he won. Curious how far away such a scenario might be.
I heard that we had sent robots to Mars. (Some people don't believe that, but I do.) Some of these robots have been equipped to do a variety of sample preparations and science observations, and even to report some of their results back to Earth scientists.
Heh. I get why you're using Discord, but it's unfortunate that a project building on Matrix does not use it for chat.
This doesn't make sense to me.

Rising wages means more competition over the same resources, leading to inflation. Even inflation in some industries/products will affect the CPI.

Where would the UBI come from? Presumably it would be from those who automate. This means your claim of lower prices will likely be marginal - the people need to support themselves whether they or a robot does the work. So UBI would mostly offset.
What kind of “engineers”? I’m not aware of most engineers going through this sort of interview. Mostly just software engineers who are indeed programmers even if they get uppity about the title
I think UBI will be necessary at some point, but I'm not thrilled with the idea of millions of us spending all their waking hours on Netflix and DoorDash.
Depends how much you value your time, and how many laptops you’re buying.

Some people want their laptop to work out of the box, and will happily pay $200 to ensure they get a HW/SW combo that’s been validated to work together by the manufacturer.

If you’re a company buying 10+ laptops, paying an extra $200 per laptop is probably cheaper than the faff of separately finding and acquiring wifi cards, then finding the time to swap them all.
Nobody knows the long term effects for kids. It’s probably ok but nobody knows. The cdc isnt an organization that uses data for its recommendations and they have embarrassed themselves so much recently that nobody should trust anything they say.
>> They’re not subject to “vaccine or testing mandates”, in fact they won’t even get COVID, they’re not going to unionize, and they’re not going to quit on you.

No, but in this article they are being rented by the hour. Once you become dependent on them, their price will go up to whatever some outside company wants it to be - probably a bit above minimum wage and that's only in places where the work area hasn't yet been redesigned with the robot in mind. This will be danger until the robots become more of a commodity item, but that may eventually happen.
Indeed, GPS is the technology I always point to for people who don't believe in relativity. If relativity isn't real, then explain how GPS works!
Another possibility is that the market is changing. The age old Xeon/Core/“binned low end” model may not be viable anymore as hyperscale cloud providers start to rule and people don’t care about CPUs as a differentiator. Add in COVID chaos and the answers are unclear.

Hell I just replaced thousands of older desktops with slower laptop chips — nobody noticed. Frankly, I only bought new devices because of Microsoft’s bullshit Windows 11 requirements.

The guaranteed cash flow train is slowing down, which makes setting billions of dollars on fire with high risk fab processes a big deal.

Intel had to adapt like this in the early 90s when memory became a commodity. We’ll see if they make it.
Does Dell offer a "clean" version of Windows for the extra price? I can come up with competing reasons for why they would/wouldn't do this.
Wikipedia has a definition: https://en.m.wikipedia.org/wiki/Free_will

> Free will is the capacity of agents to choose between different possible courses of action unimpeded.
I use uBlock Origin. I'm just saying that I see blocking ads and strong arming disgusting companies into losing some of their ill-gotten profits as not much of a bad thing. I don't see any way that ABP existing is worse for the end user than it not existing, especially if you don't even use it anyway.
> Most importantly it's not a full time job maintaining it, I spend maybe an hr a month if that checking up on it.

Exactly, I want my family to be able to get the photos if I suddenly get hit by a bus. Noone is gonna be able to deal with your custom server/cronjob/etc. crap in case anything happens to you.

Over the past decade I have migrated back and forth between cloud storage and a NAS. Both of them need upkeep, either to keep footing the bill or to check the drives and replace them if they die.

I think anyone who is serious about this needs something you can put in a closet/safe/bank vault and a decade later it will still work, and the best bet is optical disks, they were suppose to last hundred years +, but that industry is kind of on it's last legs and we were never sure how accurate the longevity claims are.
Agree! I love Kindle.
The fact that so many materials science PhDs are on their board is very interesting.
Not the first time a company has pushed an update that removes important features.

To my knowledge the first high-profile instance of this was when Sony updated the PS3 to remove Linux support, which resulted in a successful class-action in the US. [0]

[0] https://en.wikipedia.org/wiki/OtherOS
An additional problem is that without "wage signals" many would work on various useless things instead of on what the society needs to be done.
Yeah, it's fine for a corporate device or a child's device to have some safety rails in place. But it's bullshit that an iOS device I purchased won't run any application or customization or OS version that I want.
There's this gem in the source:

console.log("you are being tracked");
1 and 2 will probably make sense to some. It's not something that would overcome my why not.

For 3 the biggest problem with encryption is you introduce a single point of failure, if you lose access to the keys your photos are gone.
On a simpler note I'm a big fan of keeping things as simple as I can. Encryption is not simple. It can be fun to work with and I don't want to ignore that but unless you want to do that for fun I don't think it's worth the complexity.
I live in the UK here and I have no problem with the police or government being able to read my WhatsApp messages - provided there is sufficient judicial oversight (i.e. they can convince a judge there’s sufficient evidence I’m doing something criminal).

They can already get a warrant to go through my underwear drawer, tap my phone or read my snail mail.

Why would chat messages be different?
Thank you for your response, I really appreciate it!

> Autism is not a disease.

I will try to keep this in mind in the future.
"whistleblowers" is one answer. Public APIs and contracts are another, it's difficult for Facebook to offer targeted adds to companies while hiding it from law enforcement.
1. Bitflip.

2. Copying Error ( Not sure if that is still a thing on Windows )

3. HDD failure.

A cheap, ZFS, consumer friendly, Dual 2.5" HDD DAS would have been great. Unfortunately no one is making one. May be there is no market, May be they just dont care.

Or burn it to an Archival Disc. Apple could have make an iOS Time Capsule. But they are too busy to push their service revenue.
Firefox Gets AV1 VA-API Acceleration Sorted Out
I don't understand this obsession with electronic exercise devices. The peloton, that stupid thing that mounts to the wall, treadmills etc.

Outside is so much better than all of those. I will 100% run in single digit temperatures with snow on the ground before I touch a treadmill. If I have to be inside it's weight lifting.
Yeah, wouldn't it be great if there was a foundation to advocate for being able to have the keys to your digital locks?

We could call it something like the Freedom from Locks on Software Foundation, or maybe something a bit snapper.
This puts services like Pocket or Instapaper under doubt.

While in a browser the "reader mode" or an and blocker may reformat content and remove ads, etc, it's done strictly for the browser's user, the modified version is not distributed.

But e.g. Pocket allows to share a "pocketed" article with all the ads and most formatting removed; they even advertise some articles on their homepage. This may count as distribution of a derived work. They of course give the credits and a link to the original, but I wonder if some publishers might be unhappy enough to challenge this.
The horizon problem for faster than light travel
Most people’s referendum concepts only make it a ballot based on a swell in support for the referendum to begin with. A decent threshold of the population needs to want any particular measure to begin with. So most things would be squashed.
Clearest and most useful descriptions I've seen by far. Thanks for sharing
It was obvious this would happen when I looked at the first rounds of trial data used to approve the vaccines. In the placebo group, we find that nausea, headache, non-specific myalgia, etc. are all common reported side-effects, in some cases nearly as common as the non-placebo group.

And then we had the media prime us with stories of people taking a day to recover after the injection, etc. The power of suggestion is quite real. It can turn a minor discomfort into something not even noticed, or into something that makes a person quite miserable for a couple days.
My Bosch dryer breaks its cheap nylon door latch every 2 years. the replacement costs $25, and could be 3d printed, or punched out of metal in about 10 minutes. once the electronics break, I'm just burning down the house and moving to the woods.
What’s All the Hype About the Metaverse?
I agree. Perhaps the U.S.'s legal framework reasonably allows this kind of behavior, but IMHO it's a sign that the framework needs legislative correction.

The first time I encountered this was when Sony advertised Linux-compatibility for the PS3, which I bought expressly for that purpose. I was shocked when a judge upheld Sony's post-sale removal of that capability.
> Some indie devs are seeing Steam cuts of 46% due to fraud purchases and refunds.

Which devs and are they selling enough copies for 46% to be a meaningful amount?
> More seriously, seems like the job market is in a perfect storm for more robots to be hired in workers’ steads. They’re not subject to “vaccine or testing mandates”, in fact they won’t even get COVID, they’re not going to unionize, and they’re not going to quit on you.

And, unlike labor with payroll tax, you don't pay special supplemental taxes on automation rental.
In science, when testing the existence of something, the burden of proof is generally on the one hypothesizing the existence. The existence is generally accepted if experiments fail to reject the hypothesis.
> I've found even a slight curve of my neck creates a lot of discomfort especially when running or walking.

Just because you personally had this experience doesn't mean that everyone does.
No they aren't being honest. Almost anything can be used in an unsafe manner if the desire to do so is there. Fundamentally you have a belt whipping around on two rollers at speeds upwards of 10 mph. It's an unsafe, if used improperly, machine to begin with.

The safety argument isn't so much an argument as it is a trigger word to elicit a response in people.
I think that's something we can't claim or know without the actual UBI proposal.

If it's half the price to run a robot compared to using a human, then jobs can be eliminated even if the people want to work.

I hate my job. If they started a UBI that actually covered all the basics - food, housing, healthcare, etc... I would quit and I'm not even in a low paying job.
The first person to mention trolling is invariably the troll.