skysight-inc/HackerNews huggingface dataset:
Why is the native hiv sequence (which has had a lot of convergence potential since hiv mutates, a lot) different, and why did it convergently evolve instead to the nucleotide sequence of moderna's artificial furin site (designed for hiv), which to be fair, is subjected to industrial selection, which would be (I would guess, but don't know) weaker than the natural one due to selection sampling limitations?
>> certain Medicaid benefits

Assisted Living and Nursing Homes. Medicare makes you burn thru your assets before they start paying.

You get charged $5K/month until you are broke. Then Medicare pays the place 1/3 that price for the same care.

Largest wealth confiscation scheme ever seen. Inheritance? No, sorry.
Seconding this. The NC10 was an amazing little thing for writing a lot when on the go. Too bad the white screen issues have killed most of them off by now.
Company Culture for me. I absolutely hated the company culture. But me leaving now is unrelated to the 'great resignation' as it wasn't due to compensation reasons. I will never work for a company that will have me compromise my ethics to make a dollar, and that's what they wanted me to do.
It's a pithy saying. It's basically shorthand for: "nobody wants to put in the work and adjust their lifestyle to achieve that goal of being ripped". But I wouldn't say doing 3x or 5x sets of lifting heavy weights ever is "fun"- you just get used to it.
They don't have to raise prices, they're just doing it because they can. They made 1.4B on 7.4B of revenues in their last reported quarter. [0] It's not like these companies that are raising prices are losing money. Netflix is running a pretty consistent 20% profit margin.

[0]: https://d18rn0p25nwr6d.cloudfront.net/CIK-0001065280/19cd535...
> And not far fetched.

Can you point me in the direction of some stuff that supports the likelihood of these scenarios? The middle latitudes being unlivable does seem extreme and unlikely to me, especially given the explanation in the article about how 85F was used as a threshold for unlivable by some studies.
Oops, sorry about that. I never had an issue before...but funny after visiting HN, see exactly what you mean. (Clearing the cookies avoids the classic rick roll video). Anyway, yeah i guess the tilde folks are "characters". But, separate of that, the community i've interacted with is quite fun, respectful, and good-natured. I also failed to mention a sort of equivalent to HN, which i frequent (with similar topics to HN but often nicer crowd): https://tildes.net/

...Tilde.net used to be only open to invite not open to anyone creating an account...so if interested - and still not open to the public - i can trigger to send you an invite.
Haystack could be a good starting point, but I evaluated it at the beginning and did not suit the project requirements. It's fine for managing the document store (I use Elasticsearch) but there needs to be article reranking/relevant info extraction logic beyond what Haystack provides.
Does LAPD have zero jurisdiction on rail lines that have their own private police?

Or is it a case of “well, someone else could deal with it, so we’re out”?
> are these signs of a failing start up

Wrong question.

"Are these a signs of a company where I would waste my time and wouldn't learn anything substantial" or "Are these a signs of disorganized management which wouldn't help me [or even would harm my development]" are slightly better ones.

Of course you should always adjust your answers on your compensation and requirements.
For a brief while after getting vaccinated, before Delta and Omicron, my friends, coworkers, and I felt we were out of the woods. We are actively going out together to our favorite hangouts and being normal. I didn't think we would need this site.

Finding out that my Governor let a million tests expire rather than give them out, make me happy this site is available. I'm glad I can rely on the federal government to fix what my state government is ruining.
Why are they not just being sent to everyone?

There's a lot of potential good in sending them to people who will never request them.
TAI is the 'UTC without leap seconds'.

UT1 is an evolution of solar time, and wobbles when Earth does because it's using the Earth and Sun (and other bodies) as a clock.

UTC is TAI with leap seconds added when UT1 drifts too far away.
At least on Indeed 1/2 to 2/3rds of job postings for C# developers include salary ranges, and I'm sure it's similar for other languages. It's pretty nice for getting an idea of what you're worth.
Listen to your wife here, the subtext of that comment might be that your employment is straining your relationship. I had to learn the same lesson recently, and with three kids, you have too much to lose to ignore any warning signs there. Have you ever sat down and really taken a look at what lifestyle compromises you'd have to make? It might be fairly superficial. Cook at home a few more times a week, make it a family thing. It isn't all downside living a bit more humbly.
I assume they are implying it's because there are [so many] middlemen (that take a cut and therefore increase the bill).
Absolutely! The book I mentioned actually covers exactly this. Similarly, you can be exerting yourself in one way while restoring yourself in another. (A lot of people feel emotionally refreshed after a hard workout, for instance.)
> To say "well they are all the same bad" is to be willfully blind to the basic facts.

Haha I’m not saying that, I’m saying it has nothing to do with my participation in those platforms because I know what to expect and my lack of participation changes nothing.

My words are the user experience is not different enough.

For everyone else, check out that great robust example of a web outside of browsers.
Ok, I agree with the keywords (not with content, which Grammarly mentioned as "not affect the security and privacy of our product"). But YT algorithm has been thinking about that 4 months after I published these videos and terminated my account (without any strikes) 2 days after YT terms was changed https://www.youtube.com/t/terms
Not sure I understand the distinction you're making, isn't interviewing with one particular company a one-off game as well?
Didn't interest rate plummet during that crisis?
I hesitate to ask, but can you provide some context for linking anti-systemd sentiment with fascism?
Working at a company where middle-management is incompetent is common. Particularly in startups where they promote from within or the leaders haven't seen good management before. That being said, if you aren't getting your best work done, it's probably best to leave.

That being said, regarding whether or not your startup is failing, its hard to know (even from the inside). But one thing that is important is whether the leaders of your company think they are failing. That is easier to notice and is a shittier experience than just if your company is failing but your leaders see a way out. If your leaders think they are going to die, the easiest way to know is when the free stuff gets taken away (swag, coffees, expensed lunches). The other is if projects keep getting killed and new ones that get promoted as the answer to all the problems ... sign that they don't know what they're doing.
That would be like Islandia resurrecting British Empire. Literally, well maybe actually Islandia has more right to do so than Russia have anything to do with Rus'.
Looks like very useful tool. Will definitely play with it.
People haven't changed, times have; the market currently favors employees in a way that pushes poor HR policies from "annoying" to "people call your bluff".
Generally for perf critical use cases you dedicate the machine to the database. This simplifies many things (avoiding having to reason about sharing, etc etc).
I’m not sure comparing benchmarks of yet to be released hardware is super useful, especially given intels recent track record. I’m more likely to believe nvidia’s shipping estimates there.

I’ll given them both props for not pulling that ludicrous bullshit graph that apple had in the original M1 announcement.

An interesting feature of SPEC that strongly disadvantages Intel is the a number of SPEC tests use ‘long double’ which every platform except Intel is always 64bit double running on modern execution units.

For Intel (and AMD) the ABI for 32bit, and 64bit on linux and macOS is to use 80 bit floats. That necessarily means x87. So no SIMD, a vastly slower execution engine, and higher precision. There is no case where x87 performance comes close to the primary floating point pipelines.
How your servicer handles property taxes and escrow can have a material effect on a household’s cash flows. Often time this is a very negative effect.
Adjustable rate mortgages (ARMs) weren't even available in the US until 1982, Congress didn't allow them. They're still around, the type you describe is a 5/1 ARM. Fixed rate for 5 years, adjusts every year after that. 3, 5, 7, and 10 year ARMs are common. A 5/1 loan rate is about 1% lower than a 30 year fixed now. It doesn't make much sense to me to take the risk with rates as low as they are now.
Oh for sure there's tons of benefits if it can be made to make sense. I'm going to get one as my solar and battery capacity grow. But right now it's unimaginable to do so in PG&E territory where electricity prices rise 4-5x faster than inflation. I'd rather roll the dice on geopolitics for gas pricing.

See slide 16, which already looks quaint just a year or two later.
https://autl.assembly.ca.gov/sites/autl.assembly.ca.gov/file...
There can be a data race any time a processor loads a value, modifies it, and writes it back. Without an atomic update operation like compare_exchange() generally you need to lock the database file against other processes and threads. The typical solution is to only have one process update the file, only have one thread perform the writes, and combine it with a TCP server.

Suppose you have a big data file and want to mark which pages are occupied and which pages are free. Suppose a writer wants to read a bit from an index page to the stack to check whether a data page is occupied, modify the page bit in the stack to claim the data page if another process hasn't claimed it, and write the updated value back to memory to claim the data page to store the data value if another process hasn't claimed it.

If each process read()s the index bits, they can both see that page 2 bit in the index is unset and try to claim it, then write() back the updated index value. The updates to the index will collide, both writers will think the claimed page 2 when only one should have, and one of the data values written to that page will get lost.
I left my last gig as a datacenter tech when my employer made it abundantly clear that any of us dying of covid were “acceptable losses”. At the outset they immediately moved to make sure we were classified as “essential” and then attempted to compel us to keep working. When employees began dying I left.

Because fuck you thats why. I’m not dying so some douchebag can have a second yacht. I’m happy to let the entire system burn to the ground.
Late to the party, but I prefer the more manual version:

loopTapApp.setArc=function(){this.arc=[0,359];}
Can get 2 years of a VPN for like 70. Your pushing a hard buy ketflix. 240 a year vs 35...I feel like ketflix is about to lose another year in our house. It can go the same way as prime,Disney,Stan,paramount.

Which is the f outa my house. Have just run through a bunch of free months on all of them. What a convoluted sh*thole of an ecosystem. Standout failures are prime offering season 2+ of some series...but not season 1. Netflix constantly reduces their catalog. They all seem to do shit like film one two this platform but film 3 in the series. Nup just like...not even on the internet due to some wack licensing bs from 20 years ago or something.

3/10. Wouldn't recommend.
A servicer's records are probably your best defense against a robosigned foreclosure.
These would have been nice earlier. They've been out of stock for a long time, and I know people who had to use up their vacation days waiting for them to come back in stock because their employer wouldn't let them back in the office until they showed a negative test result.
How well do you cope then with e.g. Germanic and Eastern European features (such as vowels ä, ö, ü/y, y/ы and schwa, difficult consonant clusters, and short/long vowels and consonants independent of stress)?
The zen of dwm is endlessly browsing this list of patches and eventually adding so many that any new patches cause merge errors that take a long time to untangle: https://dwm.suckless.org/patches/
By the time you think you need one, and the delay in shipping, its already too late. But its something, I guess.
My wife needed a test, 3 weeks ago and I believe she is still waiting for them to arrive from the State.
There was just a Chronicle article on this https://www.sfchronicle.com/bayarea/article/San-Francisco-AD...

Honestly, I agree with one of the quoted people that ADUs are just a political hack to get a half-measure by the NIMBYs.

Even if we converted all the garages it would an extremely inefficient way to construct more housing. There was talk of trying to do financing for poor people to do the conversions, but insofar that that works I think it is likely to push up construction prices because ADUs are so inefficient.

(Conversely, the externality of decreased parking is quite good. I don't want to neglact that.)

If we really care about housing and equity for the poor, we should allow poor homeowners to trade in for a new condo if the entire block agrees, and then redevelop it at a massive scale. Far more housing, still equity for them, and once you bootstrap the process no one even need be displaced out of the neighborhood. Win-win
France has recently given up entirely on fast reactors, mothballing their proposed new program.

https://www.powermag.com/france-scraps-fast-nuclear-reactor-...

In addition to be bad news for fast reactors, this also means France does not see nuclear being a major factor in avoiding global warming (a nuclear powered world using burner reactors would run out of uranium very quickly, or would need to tap vast new sources at dubiously low cost.)
Astronauts on the space station work out nearly every day for several hours to stave off atrophy and still have issues. Leaving someone sedated for months in a zero G environment would make the atrophy far worse.
Not collaborator, but maintainer. In total I receive about $500 per year, with typical bounties of $3-5 per month per person.
Back when I left there was a ceiling to compensation but no limit to exploitation. More and more would get piled onto me, more and more skimmers would be inserted between me any my salary. It just got to the point where there is not a number that would justify the way I was living.

I wasn't and didn't have in prospect a way to get the compensation in accordance to my supposed worth to any of the companies I worked for. So then I asked myself where is that money going? What am I enabling by being locked out of that much cashflow?

Following up on that direction of inquiry got me answers that I could not, physically endure. I will never be able to trust the judgement of others come before me they way I used to. The game I inherited was nihilistic to a degree incommensurate with the crowdedness imposed by growth.

Those come after, that game will not inherit. Their landscape is cynical and disjointed from the reality of people around them, aimless in it's idealism. It is possibly the right way for them to be, to survive or even thrive. For about 4% of them. Same as the nihilistic system was benefitting about 4% of us back in my time. Probably was the same back when it all ran on slave labour.

I got to understand Thiels' "competition is for losers" quip. 96% are flushed out, so this must be what the system is for. Selection, not improvement or enrichment.

But I sure know I won't be participating. You can't "change the system", it can only die to a more cynical system. I've seen it happen and I'm not playing any more.

I will not be voting. I will be doing.

My children will not go to your schools. I will be teaching.

I will not listen to a doctor that never leaves his office and is paid for my being sick.

I am too old for this shit.
Can't help but to highly recommend the recent book by Philipp Dettmer, Immune: A Journey Into The Mysterious System That Keeps You Alive. It's fantastic and very readable: https://www.amazon.com/dp/B08XTNHRR5/ref=cm_sw_em_r_mt_dp_FX...
Also, although this might be more obvious to people familiar with any C-like language, C++ considers that since 'x' is a character, and its characters are fundamentally just an integer type (maybe a signed 8-bit integer, it depends) the third list is just two constant integers, which are a perfectly reasonable thing to put in a list. Even though that's obviously not what a human sees.

In a language that isn't just pretending to be strongly typed, the compiler would notice that char and whatever-integer-type-42-is aren't the same type, and it would reject your program as nonsense.

But that confusion gets much less chance if the language explicitly distinguishes initialising collections so that "I want N of X" is different from "I want N, and X". Compare Rust's vec! macro:

let mut v = vec!['x'; 42]; // NOTE semi-colon. Compiles, vector of 42 x characters

let mut v = vec!['x', 42]; // NOTE comma. Does not compile

let mut v = vec![b'x', 42]; // NOTE comma. Compiles, vector containing 120 (the ASCII code for 'x') and 42 as bytes

let mut v = vec![b'x'; 420]; // NOTE semi-colon. Compiles, vector of 420 bytes with value 120

let mut v = vec![b'x', 420]; // NOTE comma. Does not compile unless you explicitly tell Rust that you mean the low 8-bits of 420 if you do this

I'd actually be enthusiastic about a Clippy warning for the middle one, because it feels like the odds are better than they should be that wasn't what you meant. But on the other hand, the odds of you wanting either possibility are slim, so, not a priority.
This doesn't have basically anything to do with the linked article. This study suggests that the oldest known Homo Sapiens fossils in Africa are even older than previously thought, which gels with other evidence. Here's the abstract:

"Efforts to date the oldest modern human fossils in eastern Africa, from Omo-Kibish and Herto in Ethiopia, have drawn on a variety of chronometric evidence, including 40Ar/39Ar ages of stratigraphically associated tuffs. The ages that are generally reported for these fossils are around 197 thousand years (kyr) for the Kibish Omo I, and around 160–155 kyr for the Herto hominins. However, the stratigraphic relationships and tephra correlations that underpin these estimates have been challenged. Here we report geochemical analyses that link the Kamoya’s Hominid Site (KHS) Tuff, which conclusively overlies the member of the Omo-Kibish Formation that contains Omo I, with a major explosive eruption of Shala volcano in the Main Ethiopian Rift. By dating the proximal deposits of this eruption, we obtain a new minimum age for the Omo fossils of 233 ± 22 kyr. Contrary to previous arguments, we also show that the KHS Tuff does not correlate with another widespread tephra layer, the Waidedo Vitric Tuff, and therefore cannot anchor a minimum age for the Herto fossils. Shifting the age of the oldest known Homo sapiens fossils in eastern Africa to before around 200 thousand years ago is consistent with independent evidence for greater antiquity of the modern human lineage."

The African origin of Homo sapiens is pretty well established these days.
Oh, don't be dull ;) the explanation when selecting a language:

> Concepts in Swedish That are difficult to easily and directly translate to other languages.

Of course you can explain the concept in English, but you couldn't replace it with a simple translation when used in a sentence. Of course it's just a matter of degree since most words have slightly different connotations in different languages, but I found the lists entertaining and insightful.

The quality of the entries vary, of course, but that's not an issue with the premise…
In Canada, the price for the detached home that you want increases faster than the townhouse you could afford, so the plan of buying a starter home to help buy the home of your dreams is not really sensible anymore. It requires your other wealth/income to increase to compensate for the different appreciation rates of the house vs townhouse, or for you to move further and further from your current location, which will probably negatively affect your income or at minimum, your quality of life.
Something I've been thinking about lately is how browsers have essentially become a dependency for any sort of auth on the internet. Pretty much everything uses OAuth2, which requires you to be able to render HTML and CSS, and in many implementations JavaScript.

That's ~20M (Firefox) to ~30M (Chromium) lines of code as a dependency for your application, just for auth. This applies even if you have a slick CLI app like rclone. If you want to connect it to Google drive you still need a browser to do the OAuth2 flow. All of this just so we have a safe, known location to stash auth cookies.

It would be sweet if there was a lightweight protocol where you could lay out a basic consent UI (maybe with a simple JSON format) that can be rendered outside the browser. Then you need a way to connect to a central trusted cookie store. You could still redirect to a separate app, but it wouldn't need to be nearly as complicated as a browser.
It's not completely about time you mean. Time is just a rough proxy for experience. It's not just about significant accomplishments either, but rather significant accomplishments that are recognized by your employer. For all you know that senior engineer was single-handedly key to their last company's success, but their manager got all the credit while the engineer got a 1.5 multiplier on their annual bonus.

But sure. My question was more about the meaning of principal where you are. At some places it's more like just another grade of senior engineer. While at others it's equivalent to a decent rung of middle management and part of a different salary range, to which the current discussions about tech employee pay may not apply so much.
Why I Stopped Posting Daily
And along with CFS/ME, also look up POTS, MCAS/MCAD, and EDS. My wife had a very bad bout of mono in late high school and 15 years later developed POTS, MCAS, and what the rheumatologist called "unspecified connective tissue disorder," which seems like a mild case of EDS. After 10-15 years of trying treatments, she's significantly worse off. :-/

There are tons of people (mostly women) out there with this set of conditions, and they're only starting to be taken seriously. It's a set of life-altering conditions and dealing with the medical system when you have it can be infuriating and exhausting. I hope you don't have any of these things.
At least we can all agree YHWH was a bit more more polite about it than, say, Zeus would have been.
YT changed their ToS on Jan 5 https://www.youtube.com/t/terms and after 2 days my channel was suspended
I find their public response unprofessional and immature. The Nuclear regulatory process is similar to other federal and international public-safety regulatory processes such as aviation, medical, and wireless: companies soon learn that it is best to work with the regulations and regulators and not fight them.
It is not clear that interest in extended computer use isn't gendered. For example: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3166361/
Russians sold RD-180 with technology to reproduce them in USA. It was just too expensive to make them in America, so eventually Energomash got all orders to make them for Atlases. And now Falcons are pretty good too, so less need in RD-180 - Orbital still buys RD-181, single chamber engine though. And Raptors could be in use soon. And BE-4 from Blue Origin hopefully will power new ULA Vulcan rockets soon too... and that oxygen-resisting metallurgy is likely used at least in some of them (RD-181 for sure).