skysight-inc/HackerNews huggingface dataset:
I missed some guidelines stuff; there's a separate section for role in the offense, and another for obstruction. The tally I get:

7 (Base offense)
+24 ($140MM in damages)
+2 (10+ victims)
+2 (Sophisticated means)
+4 (Leading role)
+2 (Abuse of public trust)
+2 (Obstructed investigations)

That gets us level... 43. Yikes.

Consecutive vs. concurrent isn't the issue here; doing a $140MM wire fraud puts you on the hook for an insane sentence.

So this is a case where the whale sushi sentence is... theoretically possible?! Wow.
The jury made no judgements as to the efficacy of the tests. In fact, both the prosecution and the defense stipulated that the Theranos project was a failure. The defense even stated that "Failure is not fraud." The question before the jury was whether or not she had defrauded investors.

They decided that she had.

FWIW, every single firm that had medical expertise declined to invest in Theranos. They could see it had extremely minimal chance of success.
I’m in Australia and people are starting to get back into it. Cannot say about Bay Area as it’s been a while since I’ve visited.
Sentencing always happens at a later date after conviction to leave time for a post trial hearings so that the defence can raise their concerns etc.
Someone who works in medical research once pointed out to me that some research is intended to be confirmatory (i.e. confirming a hypothesis) but other research is actually intended to be hypothesis-generating. This definitely seems to be the latter.

My read on this is that we really don't know what causes things like schizophrenia, so much so that we're not even sure what to study to try to determine the cause. But the authors of this study found that a specific diet in mice with specific genes causes something that looks sort of like human psychiatric disease. They also found similar brain changes in both the mice and humans with psychiatric disease and that aspirin prevented some of the symptoms and brain changes in mice (which possibly suggests the brain changes are related to the behavioral symptoms and not just coincidental). Based on these results further study of, for example, GLO1 deficiency and/or the brain changes they found might be justified. So basically the takeaways are questions about whether/how these finding relate to human disease.

In the end, like most hypothesis-generating studies this strikes me as vaguely interesting but probably only really meaningful to other researchers in the field.
That assumes the origin is Africa, but it could have just risen to prevalence there. We know the original COVID-19 was spreading around the world when at the time we thought it was mostly China. It needs only a 12-hour plane ride to get to the other side of the planet.
Reverse engineering is an important right that is protected by centuries of patent and trade secret law in the US and many other countries. It's fundamental to innovation, even though non-innovative bad people like Theranos also do it.

Reverse engineering is not bad, and it is dismaying that someone posting on a site called "Hacker News" would think so.
Great / prescient comment here: https://news.ycombinator.com/item?id=6349808
If the author actually had some kind of evidence that there was a lab leak source of Omicron, don’t you think it would be mentioned in the opening paragraphs of the blog? Instead we have a long list of connect-the-dots tweets, out of context quotes, and unsubstantiated speculation going on for 2/3s of the post before we even get to the Omicron stuff.

The meat of the speculation is a scary looking graph plotting genetic delta from the origin. Here’s a more objective plot from the Wikipedia entry: https://en.m.wikipedia.org/wiki/SARS-CoV-2_Omicron_variant#/...

Notice anything? Looks like Gamma and others have similar genetic distances without other mutations.

Sensational blogging is pretty sensational. That’s about it.
An interesting reflection is how quickly research around TTS/STT has progressed. I remember reading [0] thinking we were a long ways away. And things will get way better with multi-task learning and multi-modal learning in the coming years (or months really).

In fact, just a year after this post was written, CoquiAI started their open source projects [1].

[0] https://news.ycombinator.com/item?id=22869365 (https://thegradient.pub/towards-an-imagenet-moment-for-speec...)

[1] https://star-history.com/#coqui-ai/TTS&coqui-ai/STT
Author, what does "C# operations" mean to you?
That was just one test, for Herpes.
It isn't just wet markets, it would be animal farming in general. We've seen that mink farms have the same problems. Pigs were the source of both the 2009 and 1918 H1N1 pandemics. Chickens and other birds farmed for food could be the source of a bird flu pandemic.

The correct response would be to start shutting it all down. All farms with crowded animals are bioreactors which create "serial passage" experiments which can be utilized by viruses for natural gain of function.

That will sure as hell not happen, not in my lifetime anyway.

And we'd have to admit that the vegans were right all along for a start.

I have this funny mental image in my head of all the people who like their BBQ and smoked meats an bacon one day waking up in the morning and realizing that the pandemic was due to meat farming and everyone shuffling off to apologize to the local vegan community one by one like they're repenting their sins. The way that feels so absurd and the contrast with all the common vegan jokes and acceptance that to be part of our culture that you have to eat meat shows how that just isn't going to happen.

So we're probably going to be back here in another 5, 10, 20 years or so...

(And I'm not vegan at all -- but the pandemic and things like the New Brunswick disease have me thinking of at least shooting more for a flexitarian diet)

Oh although the original transmission from bats to humans may have been due to bat guano farming, which is used to fertilize crops, so not even the vegans may be untainted.
Weren't they secretly testing blood samples with actual working machines?
The one of the widely used light sources for EUV lithography uses a laser to zap molten tin to get the tin plasma to ionize and emit EUV light. It's fairly exotic and really inefficient but is needed for the smaller node sizes.
> Likewise, it's not that there's compelling evidence of a lab leak (now or in 2019/2020). It's that we're sort of left with it by process of elimination. For example: if Covid-19 came from an animal population (eg via Wuhan wet markets) then why hasn't that population been found? The sources of SARS and MERS were, I believe, found relatively quickly.

there's a great deal of compelling evidence for alpha leaking from a lab; e.g. the director of the WIV publishing papers about introducing furin cleavage sites, which have otherwise never been detected in coronaviruses, into bat coronaviruses in the years leading up to the pandemic. if anybody has not read the nicholas wade essay in the bulletin of atomic scientists from last year that was mentioned briefly in the linked piece, i strong recommend it: https://thebulletin.org/2021/05/the-origin-of-covid-did-peop...
There is a "draft" entry, that looks ready to use, except the gatekeepers won't let it get published.
I'm seeing pallet loads of STC 360W rated silicon based (mono or poly) PV modules at $0.42/watt to $0.51/watt now, how much cheaper are we talking here?
Sadly voters don't make for much of a lobby these days.
There is nothing wrong with "carbs" that are not sugar. Starch is made out of glucose, which is generally harmless. Oatmeal has lots of fiber. The problem with sucrose is the fructose that makes up half of it.

Fruit almost always has plenty of fiber in it to modulate sugar absorption long enough that your gut bacteria get most of it. So, fruit is harmless, except grapes, which apparently have had the fiber bred out of them.
I agree it's reasonable in the circumstances you mentioned(as in, being charged for the resources until they are actually terminated, even if it might take a couple of minutes/hours for them to be terminated after closing the account), but the way I read it was like it could keep unterminated services running indefinitely.
How does one go about finding a third party to front the cash and split the upside? And how do US federal taxes work in this situation?
A sentence of 10 years or longer seems excessive in my personal opinion as well, but I can't help thinking that the baby only entered the picture when she was already facing those criminal charges, so there might have been an element of calculation involved.
It seems like every hardware vendor (and sometimes each compiler) provides its own syntax for assembly code. Leaving aside the obvious fact that each ISA has its own instructions, nearly everything else varies from one assembler to the next.

Are clobbered registers the left-most or right-most argument? How are comments expressed? Are operands separated by space alone or with commas? How are jump target labels expressed? How are addressing modes expressed? Go source diving in the FreeRTOS source code and you'll see that even when several different compilers support the same architecture (eg ARMv7-M), they will all have slightly incompatible assembly code syntax.
do you have a link to a source or more discussion on this?
but not quite as good as seeing credit card transactions in real-time like Google does via gmail scraping.
It is arguably worse if fructose actually turns out to be the issue.
* Location: U.S.

* Remote: greatly preferred

* Willing to relocate: likely only back to NYC

* Technologies: Jamstack atm + Python, Bubble, & others; C, C++, & C# long ago;

* Résumé/CV: dev, founder, CS PhD, Techstars alum, building sloop.ai & breezethat.com, founded AI dashcam company, USAF vet -> re: https://linkedin.com/in/dotdotjames

* Email: DM on Twitter, @DotDotJames -> https://twitter.com/DotDotJames

* Interest: part-time roles to boost the right founder or team
It's because aside from the "nuclear steam supply system", a DT fusion power plant and a fission power plant would be the same. The non-nuclear parts will be similar (or cheaper for fission; a fusion plant needs a cryo plant and a tritium recovery system.)

A fusion reactor will likely be MORE expensive per unit mass (or volume) than a fission reactor. A fission reactor is a rather simple thing, operated at relatively low thermal and neutron loading.

Fusion's only real chance would be if some of the non-nuclear parts could be avoided, for example by direct conversion of plasma energy to electric power (so no or smaller turbines/generators). This would require advanced fuels (like DD or D3He).
Gas station or self storage. It’s basically a land squat. A chain of coffee shacks would be viable too. Reselling shoes is viable but not good for getting more laborers.
A child care or tutoring facility would be a good choice too. But lots of work.
Otherwise maybe eth mining would be profitable even on gpu in a year.
Ideally you would buy some equipment that’s easy to move and retains value then sell it off after 2 years with minimal losses.
Power Steer: Long form essay on feedlot beef (2002)
Seems odd that it lists /home to pick a user, instead of getpwent.
She didn’t personally clear or keep anything close to a billion dollars. It’s true that she was able to live a somewhat lavish, albeit clearly stressful, lifestyle for a while though…
Sure, fine. I stand corrected and remain unsatisfied by still not hearing any clear or compelling reasons to shorten copyrights. Congress isn’t extending copyrights on their own, their doing it because they’ve been asked to by businesses like Disney. The length hasn’t been extended “dramatically”, any time recently. No more dramatically than in the past. https://en.wikipedia.org/wiki/Copyright_law_of_the_United_St...
Do you break up large foreign corporations? Samsung? Sony? NEC? Philips? BASF? Volkswagen? Oppo? How do you do that? Or do you let small US companies duke it out with foreign giants, without the benefit of scaled efficiency?
"If you just look at the dollars and cents, they should be inventing new technology at a similar rate as the US"

That's very debatable.
Maybe you are taking all the improvements China has made in construction, manufacturing and nuclear industry, and assigning them an 'innovation value' of zero.
Maybe you are assigning non-zero innovation to exploiters of gig economy like Deliveroo.
For SARS-1 there was no lab in Guangdong and still a coronavirus that is found in bats 700 miles away wound up jumping to people in a dense urban center.

If you can explain how SARS-1 happened without a lab -- and you MUST be able to do this at the end of the day, because it really did happen -- then you can explain how SARS-2 happened and the lab was just a coincidence.
The Open Organisation of Lockpickers (TOOOL): 2021 Announcement [pdf]
I would just add that on kookier platforms, sometimes there more low hanging fruit to be picked up with asm. I can still (barely) beat sha256 on the arm64 using the hardware sha calls that not everyone implements, stuff like that.
Faster IndexOf for Substrings in .NET
I would guess as:

1. For a lot of companies that have sites running the site is not their primary business. E.g. bank's business is not their site. Surely, their customers (maybe majority of them even) use the site, but that's not what they came to the bank for, that's something they are forced to endure to get their loan, access to their money, their credit card account, etc. Consequently, no motivation to improve UX.

2. A lot of companies that do run their business via the site, they are big enough so that losing any particular customer is below rounding error for them. If you're mad at Amazon for scammy products, what you're going to do, use... what exactly? Not many sites have as wide catalog as Amazon, and can seriously threaten to take their customers. Consequently, no incentive to improve. Also, automatic problem handling tool cost much less than live support (that would demand benefits, complain about working conditions, and generally cause headache) - and if that costs 1% of customers wrongly banned, the cost is acceptable. In any case, not a lot of people would abandon Amazon because there's 1% chance they'd be banned by mistake - and in fact, nobody even knows how big the chance is anyway.

3. A lot of seemingly independent sites are actually owned by the same company (travel industry is notorious for that). So, if you don't like the UX on the site A, and take your business to the site B, you're didn't take your business anywhere in reality, you're just moved to the next isle at the same store. Same consequences.

4. Scammers are much more motivated to scam than services are motivated to fight them. If a scammer scams Google, they get $$$BIG BUCKS$$$ (or at least make a living). If Google catches a scammer, practically nothing changes in anybody's bottom line. Consequently, you get scammy search results.

5. Not changing anything and just keeping everything worked as it worked before rarely gets people promoted. Reworking the whole site and successfully implementing a buzzword technology and completing a project with 100 people involved in time and under budget - just might. Consequently, unnecessary redesigns all around.
what about a real time white english to ebonics/jive translator, when are we going to see this...
Yeah, I think this is in part an outcropping of the Friedman/Chicago School notion of firms as purely self-interested - the notion that one can ignore the actions of the other actors in the space when planning one's own strategy is sort of silly on the face of it.
Did forums ever make money?
Yeah but since spring 2020? This variant slept without getting replaced by other more contagious variants? That doesn't seem likely.
I'm reading the jury instructions here: https://cand.uscourts.gov/wp-content/uploads/cases-of-intere...

Would the jury get this document with the blue and yellow highlighting??

> Language proposed by Ms. Holmes, and objected to by the government, is highlighted in blue. Language proposed by the government, and objected to by Ms. Holmes, is highlighted in yellow.
Besides, you don't become _more_ "ready to re-enter the workforce" as your life quality and health deteriorate from poverty.
I worked at a facility with experimental lithography machines. One of the
nasties looked like water, but would pass through your skin and melt your bones. Fun.
Welcome to HN. Can you comment on the silent/functional mutation ratio weirdness?
I laughed at the CueCat, but now I wish I had one of my own.
Ouch. That's even more ridiculous, given how few variables are involved in SATA power management.
Honestly, the worst part is we find the short supplies are in these stupid, low-end, cents-a-pop chips that have nothing to do with high end processes. Especially in PSU applications.
Sometimes, yes. Interestingly these ridiculously reactive materials aren't the ones that tend to contaminate the environment most; they don't last long enough outside a carefully controlled lab. It's, surprisingly, the almost nontoxic materials like perchloroethylene that tend to cause big headaches, because they're unreactive enough to survive in the environment for many years.
While I'm not sure about some of the half-said political attitude in this post, I do strongly believe in what the author is getting at, and am also building a company for "the Small Web". 1

I've been working on an essay for quite awhile now on a similar topic: what does a decentralized web actually look like? If Big Cloud is an empire-sized industry and Blockchain is a wildly re-engineered approach to solving the centralized app problem, then the simple dark-horse is just more folks running server software (at home or just on computers they own). TCP/IP and HTTP as-is decentralize just fine - we have an education and tooling problem, not a technical problem.

> The spiders that sit at its centre waiting to suck you dry are Big Tech people farmers like Facebook, Google

Look, Big Tech doesn't have to be evil for there to be advantages to running your own software. There are _much more immediate_ benefits to every day people, like owning all the rights to all the pictures of their children, seeing fewer ads when consuming media, or having a way to host a website without paying a fortune 10 company a monthly stipend. Melodrama and angry politics aside, we at least agree that it's time to fix the internet :)

1 https://kubesail.com
> [She wasn’t] really being charged with [wire fraud with regard to] patients

Unless the word "really" is doing some heavy lifting here, this is incorrect. There were multiple counts directly and specifically related to defrauding patients. These counts came back not guilty, but they were, in fact, charged, and customers testified in court in support of these charges.
A lot of what made Disney so beloved is remaking and adapting existing works. There's nothing inherently wrong with the act of remixing, it is in fact the driver and source of a lot of great culture we've had the honor of experiencing over hundreds, thousands of years (yet particularly in the past 50).

What I don't understand why people seem to think Disney alone should benefit from existing works, and nobody else. Or that copyright being restricted to a single entity is the best way to ensure "good" works being produced.
I think CBC needs to return to gritty journalism, local, provincial, federal, and global. There’s no money in real journalism any more; it’s far more profitable to provide “news” entertainment, aka exaggerate and fabricate. I think the most important thing a government could do is pay a percentage of the budget strings unattached to independent, credentialed, public journalism. It helps keep a government honest.
Back when computers were just a piece o your life. Video games the same. It was a corner in your room. Now it's both center an floor.
So, like, the argument would be that it is also barbaric to sentence a homeless person to 15 years for stealing $100.
there seems to be a some conversation on going with this user in the issues. (https://github.com/BaseMax/BaseMax/issues/11)

It could be fake, or not. Just like this claim.

I am just wondering what is the added value of such post here at all. Should HN be policing GitHub users?
I vote for "webwashing".
> Reverse Engineered Siemens Tech + dilution of the blood to get enough volume is mostly irrelevant to a patient

Those machines weren't designed to work that way though, so the test results were wildly inaccurate when they did dilutions. And they fired people who wanted to delay rollout in order to ensure that they had consistently accurate results.
I am a fan of the long form interview talking to the guests for 2-3 hours versus what seems like 3-4 minutes on CNN\FOX\MSNBC\CNBC. Also the variety of guests and the diversity of their backgrounds keeps me entertained.

Any suggestions on a Joe Rogan alternatives? Already listening to Lex Fridman.
>Homeless people in American have been sentenced to over 15 years in prison for stealing $100

Using an existing injustice in the US to defend another does not make it right.

I am no fan of Holmes or what she did, but locking away people for life is clearly not a winning strategy.
We call them change freezes, they are generally done when there are less people around. This allows employees to celebrate holidays.

These do reduce, but don't elimate incidents.

Unilateral change blocks, stink, but don't put support in the weird position of taking on something they can't.
One way out is to grow a community of enthusiastic reviewers. LibraryThing succeeded for book reviews. LibraryThing book reviews are better because LibraryThing caters to bookworms.
> > I don't get any interviews at all

> Tell them that you [...]

Read better!
Not open source? Pass.
> We need another section to replace REPS AND WARRANTIES

Ain't that the truth. Hand on heart: the number of decks I saw last year that have an INSANE 2 page legal disclaimer at the start AND finish of the deck is up ~90%, ninety percent. I knew people who used this as a signal of an inexperienced founder, over night it's the signal of an experienced founder.
But that’s all it was, it told a story that needed to be told but did so using fear and exaggeration. I’ve read it.