skysight-inc/HackerNews huggingface dataset:
> Another possibility is that viral mutation rates are underestimated, and/or infections are systematically underestimated.

What is especially underestimated is viral mutation in HIV-positive and other immunodeficient people. It is suspected [1] that Omicron may have been "bred" aka accumulated its mutations in the body of such a person in South Africa... and once again, the failure of the Western nations to provide access to medical service and at least basic wealth in Africa for decades - and that in general, not just in HIV treatment and prevention - bites us in the behinds here. As long as large swaths of the continent live in utter poverty and war, it will be a giant petri dish for all kinds of pathogens.

[1]: https://www.npr.org/sections/goatsandsoda/2021/12/01/1055803...
Ouch. Indeed. Thanks for noticing this. I've reported it to our web people.

It's 925 000 px × 775 000 px which is 717 gigapixels (9 zeros).
In my opinion that Atlantic article is far from good. Its a scare piece designed to make the public afraid

Methamphetamine is methamphetamine and there is no "new meth"

It's simply a higher amount of R-meth and less L-meth(the non psychoactive isomer)

Don't believe everything you read
Could open the browser and run DaedalOS on it, but the browser inside that DaedalOS wouldn't run another DaedalOS anymore.

Hee hee.
Thanks for the clarification, I now understand what you meant by the article being unclear.
Neural Network Uses Program Synthesis to Solve University Level Math
Add "site:github.com" to your search and just get results from github.
There are no healthcare privacy laws the the USA that apply to Google. Indeed, "medical information" is not generally protected. HIPAA only prevents "healthcare providers and healthcare businesses" from providing that information without your consent. If you disclose or leak medical information to other companies, they are not required to maintain confidentiality and can sell or use that information perfectly legally.
Please explain why you think a company should provide goods for people outside their target market? Is market segmentation frowned upon these days?
Yes you're right that it requires strength. And, at the same time, people have been training other people in every profession to do their jobs for ages. It's how we have survived and thrived as a species.
Profits at the expense of others is more or less the driving force of our entire economy. Not sure how you're going to legislate that away.
I always wanted to start with generative art and this seems like a perfect starting place.

Question for people that already do generative art: what library (framework) do you recommend? I know a little bit about GLSL but I know it is limiting in some cases
Ok maybe it hasn’t taken HN by storm but at three large, public companies in my post-google experience they all had re-implemented slicer, but they all lacked other, simpler and more generally useful rpc directors that are much more common, but don’t have papers to go with them.
If I can play any decent fraction of my Steam library on a Steam Deck then it will automatically have a better out-of-the-box experience than a Switch on which I'll be limited to a relatively small number of games, most of which will cost me an extra $69 each.
4 W of power is nuts. Less than most LED light bulbs we have in the house.
What a massive waste taking out 14k in salary. Almost everything can arguably be a business expense. Plus, any investment, just use SVPs or other methods where you don't incur taxation: would make no sense to take them out as salary just to invest them to ur name rather than a company's name. One day you'll pay the capital gains (which can themselves me minimized) and just buy a villa for business events, a range rover to go to meetings, and so on, on a legal structure's name, that is. gl.
Both. It works very well for what it is. Considering that I paid absolutely nothing for it, it's great.
Exactly my experience as a student. Picked up EndNote, hated the interface and dropped it hard. I did need something to manage my references so I ended up on Zotero which is incredibly easy to use and just works. I use it to manage personal-interest files too.
I think a case can be made that Ticketmaster will be replaced (or replace itself) with blockchain tech that will eliminate scalpers. Visa and Mastercard will most likely be replaced or dramatically lower fees. Banks will be upended.
My favorite thing to do is tax shelter!

With $45k/mo income self employed, you can contribute to a self directed Roth 401k as both the employee and the employer. This boosts your maximum 2022 annual contribution from $20,500 to $60,500. You can only contribute with 20% of the revenue, so you need around $300,000 to pump the max of $60,500 into one of these. It is slightly lower if you do this through an S-Corp. So everyone is correct that you need a CPA, now that you can afford to have some real fun. There are some things that are almost impossible to do alone, or actually impossible.

Unlike corporate 401ks, you can invest the money almost any way you want - from a passive vanguard fund to the sketchiest and most exciting crypto assets - all the money grows tax free in there and is tax free upon withdrawal when you reach certain age thresholds.

Your work is just beginning!

- CPA versed in personal, business and retirement accounts

- 401k Compliance company

- Payroll company to process W-2’s

- 401k Bank account

- 401k Traditional brokerage

- 401k Crypto brokerage

- Separate wallets to never intermingle assets

I think this is achievable for ~$1200 first year with ~$900 annual fees. Split between the Compliance company, payroll company and cpa.

Eventually you’ll have enough in those to invest in private equity funds

If you’re worried about making money for the sake of it, you can always set a few foundations or charities as the beneficiary of the 401k plan, in event that you die. Or just pay a boatload in taxes for not making the transactions that Congress prescribed.

Once you get that on autopilot, then you can work on ensuring current year tax deductions. Are you getting the research tax credit due to your US-based (?) software engineer? For example. Maybe relevant for you, maybe not. CPA.
From a tactical level, I'd repeat the suggestions to find a good local accountant to discuss your issues with. I found mine through a referral from a friend who was also running a small business and he has been invaluable for years (through startups, LLCs and W2 jobs).

Since you are US based and have minimal employees, you may want to look at either a SEP-IRA (which lets you save ~$50k a year pre-tax) or a individual pension (less experience with that, but have read about it).

From a strategic point of view, I'd sit back and consider your goals. What do you want to do with that cash? Save for retirement, sure. It sounds like you've ruled out expanding the business, but there are other things you can do:

* start a new business
* start a foundation
* save for the future (non-retirement)
* optimize the business even more
* buy alternative investments (real estate, for example)
* buy a hobby farm
* work less hours

Any advice I give you on those paths won't be worthwhile since I don't know your goals. But that discussion is worth having, even if it is with yourself.
There's also creating a template database that exists at a known good state, and using that database template to CREATE DATABASE from.

https://www.postgresql.org/docs/current/manage-ag-templatedb...
It absolutely is wrong and untrue, though, in addition to being racist. There being significant IQ differences between ethnicities/"races" that are caused by genetics is a long debunked theory; just look at the scientific discourse around something like "The Bell Curve".
Then our infinite growth economy is like an invasive species that has taken over the planet. Hunting resources to extinction, growing ever larger and all-encompassing, heating up our planet with its metabolic cycle of fossil fuel extraction and burning.
Did they not implement it as an iframe?
Maybe a better way to say it is that I enjoy the process of building something with wood. If I suck at it and the end result isn't great, at least I still enjoyed the process and tinkering.

Its funny that I'm very pragmatic with software work though. I don't spend any time looking into new/upcoming languages or tinkering with compilers or whatnot unless I have a work project. It seems like a waste of time since the software world turns very quickly.
So I’d say you are less able to participate in society.
Ask HN: Looking for an open CSS variables theme that was published here
A while ago someone (the creator?) published a link to an open source css theme using css variables only ("native css"). Can't find it since then, can anyone help?
Weird to not mention Second life which basically makes its money by selling land, (which itself is tied to compute resources so it kinda makes sense).

There is no speculation though, that would be ridiculous. Decentraland etc, yeah they are major scams, but they 've already made their money.
It’s pointing out that it’s a side effect of user market forces. The point is that users keep using these sites despite all of these annoying patterns.
This website claims Hitler was set up by "international banksters" (https://www.winterwatch.net/2021/08/the-planned-bankster-dup...), and that the Capitol assault was a "psyop" (https://www.winterwatch.net/2021/01/divide-and-conquer-dc-ca...), so color me a little skeptical of their ability to read a dense set of files accurately.
> The problem with the lab-leak hypotheses is that is has no basis other than the correlation-causation fallacy. An advanced virology lab just happened to be in the place the pandemic originated because scientists identified it as a hotspot where a pandemic could start.

It's always a "kill the messenger" attitude. South Africa and the UK got punished with demonization and travel bans for doing the correct thing and sequencing a lot of positive samples to identify variants. China was also punished in a similar way, but at least there a bit of that punishment is warranted given how utterly intransparent China was and still is and how local cadres tried to hide the outbreak in the first place.

Once the pandemic is under control, humanity as a whole will have to establish a framework on pandemics that prevents "perverse incentives" aka hiding suspicious events, manipulating data, threatening researchers or not sequencing variants.
I haven’t used Microsoft Office in a decade, at least. It’s totally possible.
Read: The statement has imparted a silencing effect on the wider scientific debate, including among science journalists.
This approach relies on the backend proxying `/api` to the API. In other words, the client requests http://www.example.com/api/foo, then the backend goes off and fetches http://api.example.com/foo, then sends it back to the client.

You can’t do that because in your case only the client can connect to the local networks; your backend has no access.
> * Release Often as KPIs for developers

Not likely. Release often as a KPI usually just means that a few more bugs get shipped and bugfixes get shipped faster. Poorly designed features are usually results of poor design and nothing else.

> Payment Security and Financial Regulations

Not really. Sure, opening a bank account is painful, but setting up the app shouldn't be. I've had three different experiences: Chase (easy), Huntington Bank (security theatre abusurdium), and a Credit Union (easy). It all comes down to 2FA implementation - Huntington has a poorly designed authenticator registration flow.

> Patch-work nature of ID & Verification... Captchas, Two-factor SMS, password rules and Authentication Apps have been patched onto the original user/pass system

Yes, and it mostly works pretty well. It is telling that no one way has really caught on as the way to do it, but there seems to be broad agreement that a click verified email address is an acceptable identity. I'm not sure there's much better. What does a store know about a buyer in the real world, anyway? Physically present, with cash in hand... good enough.

> KPI switch from customer first to business model first

When has it ever been anything other than business enablement? Ecommerce has always been "customer self service" and many a support site has been built to reduce headcount in customer service. Some companies are good at this stuff, and others are not. Just like in the real world. What is changing at Google and Amazon is the focus is now squarely on making money, so losing money for long periods of time is no longer acceptable. In fact, their focus on mining profit from their users is creating opportunities around the edges... which will give rise to some very capable competitors over time.
The site makes money. /s

I highly doubt, nor expect, the OP to divulge the information you're asking for. Would you welcome 100's of new entry copy cat competitors?
You could try a self-lit e-ink (like Kindle Paperwhite) to determine whether it's the light emission.

I doubt it. I see the same kind of distraction in myself, and it's not triggered on any e-ink reader, whether lit or not. So it seems to be related to functionality indeed.

Important point is that I've never used a web browser on any reader.
Uninstalled twitter off my iphone, a great way to reclaim your life and your sanity, also noticed my stress levels dropped ;)
> There are multiple GUI toolkits that are cross platform, WYSIWYG cross-platform GUI designers like Lazarus, Java, and just plain old writing GUI code for multiple targets.

And they all kinda look and work like crap?

Take a look at Kicad (no offense to the Kicad folks--it's just something cross-platform that I'm intimately familiar with and use every day), for example, and tell me anybody would hold it up as an exemplar of cross-platform GUI development. Tk is cross-platform and cross-language, and all everybody does is complain about how it looks like crap. Blender thought GUI toolkits were so useless that they grew their own. No Digital Audio Workstation uses any mainstream GUI toolkit. I can go on and on and on.

As for computer games, they are a completely different beast. Computer games take over the whole screen, proscribe your input interface, and generally limit your ability to interact with text or graphical elements. GUI is a whole lot easier if you don't have to deal with text.
I think the issue would be less the "exotic" and more the wild animals sold in unhygienic conditions, which at least was the picture some media painted when describing Chinese wet markets.
It's a problem that we've made a reasonable amount of bragging into a social error. Your HN rank is in fact a substantive accomplishment, acknowledging that you're in the top small fraction of contributors to one of the most valuable communities on the web. Thank you for making it richer for me. And there's also nothing wrong with speculating about better uses for your time.

I don't think its assholery to make a legit brag or to bow to tall poppy syndrome. I think it's sad that the bow to the all too human neurosis has become required by etiquette.
Wasn't aware of either! But very excited by both.
The strongest argument in favor of VC would be the ability to deliver capital where otherwise none would be available, the ability to generate above-market returns (at least circumstantial evidence of offering value), and the experience/insights that emerge from experience with other startups.

The counter-argument would be, as PG alludes, the best VCs don't act like most of the others, the massive capital their business model requires them to invest causes misaligned incentives with respect to founders (e.g. the founder is happy to sell for $15M, but the VC folks are not), and there's a fair bit of IP security concern.

The bottom-line suggests a revisiting of incentives from both parties. Founders need some access to the VCs broader returns (possibly even offering their insight into OTHER businesses under the VC's flag) and VCs need to assess their returns over much larger temporal horizons than most funds will consider.
> In-game digital items, tickets, reservations, certificates, coupons, keys, and many more use cases

Literally none of these require blockchains. And literally none of these are aided in any way, shape, or form by NFTs.

For tickets specifically I already had this conversation recently, see my two responses here: https://news.ycombinator.com/item?id=29282931

> but that doesn´t mean that people aren't using them to build other stuff.

The question still stands: do show us this "other stuff" so that it actually requires this tech.

> You need to give time for actually useful dapps to actually pop up, as opposed to just slapping a price on an image and calling it a day.

Dapps have been around for 8 years now. So...
If only anyone would actually give satisfactory answers. And not wave hands and add "because blockchain".
Presumably there's no way to use Paperpile "offline"? The classic example of editing a manuscript while on a plane is something that does happen.
Banking secrecy is already dead, but it did not stop tax evasion. But if all transaction data is found on the infrastructure of a few giants, they will become institutionalized in the monetary system forever.
How mathematicians assess whether their research ambitions can be achieved?
You mean regarding the mobile phones or the whole GSM/Mobile equipment?
For mobile phones I think that they could become great again if the would focus on building mobile phones that have same characteristics as their most famous ones: long lasting battery and quality mobile phone body (hard/impossible to break).
Indeed. I've always wanted to know "Okay, so if we record real property ownership on a blockchain, and someone trespasses in my house, who do I call?"

If the answer is "the police", I'm not really sure what having the blockchain gets us, if anything at all. Recording changes at the county recorder is easy and cheap enough already, so what's the point?
> Let's consider a basic example: How can you justify not using Microsoft Office?

Easy. I don’t want to give Microsoft money and libreoffice/notes are fine for all of the basic use cases.
Talk to your accountant and/or financial advisor. I do not know much about Germany’s tax regime but in many countries it is beneficial - if you leave money inside a corporation - to have an investment account and essentially use it a pension scheme. LLC may not be eligible for that and you may need to convert to a whatever is the German thing for C-corp.
I know this project http://www.xpud.org/ . And yes, this is really a desktop mixed with a browser.
No you’re not the only one. The problem with Terraform “Scripting” is in a lot of cases it takes a loooong time to find out your “runtime” errors. These are typically fat fingered strings. I think something like AWS CDK, where you find these errors at compile, time is a better approach.
> I'm surprised by the number of people who don't get jobs due to reverse racism and then find out for a fact this was the case. Generally with 'classic' racism you're left guessing.

What is implausible about that? What you call the 'classic' type of racism has not been acceptable for half a century. Those racists have to hide or they are pushed out, sued, targeted by governments, boycotted, etc.

The new "good" flavor of racism is openly pushed, celebrated, encouraged by governments and academia and politicians. Of course many racists will openly boast about their racism, and they will be praised for it.
Association between severity of Covid symptoms and food intake
How to Reflect on Your Career?
Quartz Graphics Layer (macOS)
But land is basically a commodity in SL and prices are basically similar everywhere. I doubt there is a lot of speculation going on.

OTOH , in the open source version of SL (opensimulator) people are giving away land for free but can't find buyers.
Built on centralization but the centralized platforms only offer NFT speculation and take a huge fee. I’ll get to the “only offer speculation” in a minute. First, a huge part of NFTs’ fundamental value is people perceiving these things as valuable, ownable, rights-assigning assets, but how much would this be true if there wasn’t OpenSea? Simply because one can look up and see them on OpenSea gives NFTs value. If OS went down for an extended period, top NFT collections would drop in value.

Also the only platforms that can exist at this point are JPEG “trading” platforms like OpenSea simply because speculation is the only thing that's profitable, and because there isn’t yet any legal precedent allowing real assets to be traded using ERC721. I mean, yeah someone can try to put their deed on IPFS but what happens when something like this hits a snag and has to head to court? The fact that no one can convincingly say a judge would side with the ledger is a huge, and the reason NFT use cases are stuck in casino mode.
RxDB 11.0.0
> We were setting it up and it made her put in her email and phone number to verify. I was appalled; I was like don't put in your email! I'll return it!

I’m glad to know I’m not the only one still trying to fight this fight.

It’s really starting to be a problem with games. Buying games during the holiday Steam sales used to be a big part of my holiday break, something that was my way of winding down after a long year.

But I’ve made it a personal policy to refund any game that requires an account to play (I only play single player games, there’s no reason for games to have my email.)

Nowadays this means basically all AAA games are off limits to me. Gaming in general is becoming less and less of my life as a result. I had originally hoped that some PM somewhere would see refunds coming with “requires signup” as the reason, and would maybe second guess requiring signin for future games, but it just keeps getting more and more ubiquitous.

At this point I’m just saying farewell to gaming. It was once something that gave me a lot of pleasure, but I can’t participate in this industry any more. There’s other things I can do with my time.
I'm not using it either for personal purposes for more than a decade, but sometimes life gives you lemons at the office (the literal one), so you need to work with something you don't like for a bit.

The point I'm trying to make is, if you're exchanging files and doing collaborative work, you don't have all the freedom to do whatever you want to do.
The difficult part is figuring out why anyone would ever want to use any of this stuff for anything other than money laundering.
Engineers at Google build what the ads and sales teams tell them to.
This seems very optimistic to me. I’m reminded of the xkcd where the cryptography enthusiasts imagine that 4096-bit security will protect their secrets, but in reality no one bothers with that. If the government requires ID for crypto purchases, they can shut down businesses that don’t comply. Businesses will comply. The tax agency can audit you and see if you have nice stuff that’s not accounted for. If you have a significant source of income from unreported crypto, this will likely be evident in many ways — business relationships, web presence, letters in the mail. Very few people can actually turn into ghosts, even with crypto.
This = Pulumi?

It doesn't use TF as a backend. It builds on top of Terraform providers in many cases.
If I had any inclination and cause for terrorist attacks...
I think there is a market, and it is a lot of how disruption happens. Google was very user friendly in the beginning. Twitter too. Of course they broke that.

This might be controversial, but Apple also did it to perfection for a long time, and they still partially do, to the chagrin of all the developers in their ecosystem. But they have also succumbed to dark patterns lately too (advertisements inside the preferences app, wtf).
VC $ decreases your options considerably in my experience. But perhaps we’re talking about different kinds of optionality