skysight-inc/HackerNews huggingface dataset:
Rental cars in Mexico don't come with legally required liability insurance, and your own liability insurance from USA doesn't count. Your credit card doesn't offer liability insurance, just collision and damage protection.

I don't know if they tried to explain this to you and failed, but at the end I guess they just let you drive without legally mandated insurance and take the risk. I personally wouldn't take that risk in Mexico (or any other foreign country).
There are quality checks throughout the entire process, starting from the raw read quality scores returned directly from the sequencer all the way to fully assembled genome completeness. In our paper, one of the tools we used for this is called BUSCO[0] which scored our assembly at 97.9%, a relatively high score for de novo assemblies.

[0] https://pubmed.ncbi.nlm.nih.gov/31020564/
I'm not renting cars now, but when I did, I would just find the cheapest middle-tier car I could to reserve. The website always had, for example, a Chrysler 200 and a BMW in the "luxury" tier, the former for half the price, cus it's a POS. But, in my experience, no matter which one you reserve, you're gonna get a random vehicle from the tier (or higher), so might as well save the money.
SPAs are fundamentally flawed. I am making a webapp with lots of images and media resources to download, when the user click to another page, the media on the previous page are being still downloading in the background and choked the 6 connection limit. To avoid this I have to encapsulate the download queue to each "page" manually.

Another issue is how browser cache 404, for SPA app, the "known" routes are stored in main.js rendered in browser, the nginx doesn't know which page is not defined, so every page is 200 and then rendered 404 in browser only, the browser would still cache the "wrong" 404 page because nginx has to serve index.html with main.js as 200 first.
Peter McCullough's take flies in the face of the weight of subject matter experts and published evidence on the topic. If you like podcast format, perhaps listen to ZDoggMD's dissection of McCullough's interview https://zdoggmd.com/peter-mccullough/
Surely you don't think that it's Google's responsibility to return any random bullshit that happens to be on the internet? I go there to figure something out. I don't care that some conspiracy theorists believe the earth is flat, if I search for "theory of gravity" I don't want any flat earth garbage.
>If we're at that level of paranoid, bugs in the HTTP parser, TLS implementation, or the TCP/IP stack should be just as sensitive.

How many zero days exist when you put a new distro online in order to update, and thats without looking at the firmware for bugs.
In these times of compassion when conformity's in fashion
Say one more stupid thing to me before the final nail is driven in
- Bob Dylan, Foot of Pride (1983) rec. w/Sly+Robbie,Knopfler
The rare spots of good news on climate change
You can get a usable partial genome at home using a minion (provided you have access to basic lab equipment and consumables, like pipettes, a microcentrifuge, gel electrophoresis kit) for about $2.5k, and a fairly decent one for $5k (about 22x coverage - not perfect but plenty for most purposes).

https://nanoporetech.com/about-us/news/human-genome-minion
Wow that's creepy and fascinating. It reminds me of the way I can never quite remember lyrics and also how music happens in dreams.
IFR for males under 40 is 500/1000000 or .05% if they’re infected.

Source: https://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-scena...
I had the opposite problem, I always reserve a small four door fuel sedan, and several times they upselled me an SUV or sports car "at no cost". Well I don't like driving big or fast cars and I want good fuel economy since I'm driving 100+ miles. That's a real cost!! No can do.

One time, I took the fast car because TINA and didn't notice how light the pedal was on a downhill section of the freeway and got a speeding ticket. So that "free upsell" cost me $350.
I would presume so, though I don't have any numbers on me right now. Myocarditis was not the biggest risk from covid, lung damage/blood clots/strokes where iirc.
This is correct.

Your resume should be exactly 1 page long, and have something that stands out (company worked for, open source contributions, volunteer work.. anything that makes it be different).

If you have worked for decades, write "over 10 years experience" :)

Bullet points are good, long sentences are bad.

Listing tech/languages is a good idea if you can list a lot of real stuff. No one cares if you used ms word.

It should be 1 page!!! Don't cheat via small fonts. People can look at your linkedin if they need to know all that crap.
Syme and Matsakis: F# in the Static vs. Dynamic divide
"It is a sad and little-known reality that poverty tends to persist between generations".

Is it? To me it's intuitively obvious and I can't think of any real person who would disagree?

I can't even conceive of a different way this could work. Reducing the correlation to zero would require basically removing money's functional utility.
Yup, this happened to me all the time. My family of four will always rent the minivan, which will inevitably be swapped for some SUV. All you have to say is that you don't want the SUV, you want a minivan, but it's annoying to have to go through the charade every time.
Cultural change. Stop pushing family life as this sacred self-fulfillment fantasy it is today, but instead promote other means of salvation.

Women's equal access to sterilization would be a big one. Easy and free availability of birth control and pregnancy termination other low-hanging fruits. Improving factual constraints, education and independence: Inviting self-determined life choices and a self-serving sense of purpose.

Enforcing parent's responsibility for their children. Punish neglect more harshly. Don't allow parents to make their children's attention footprint something everyone has to endure, because "children are precious!" entitlement; no free-riding. Don't collectivize the downsides of procreation.

Basically just undo the pro-natalism ideology, religious influence and propaganda.
The untenable part seems to be 'anticipation of sticker shock' though - a reputation system would affect chronic cancelers but (assuming your PR department is on its toes) quite possibly largely not be visible to incidental cancelers or people who're not actually going to cancel and are just scared of getting screwed.

It still might not work, but as implementation approaches go, the business risks seem substantially different at least.
That is a laughable analysis. You are comparing the risk of death to the risk of a serious side effect. Why not compare apples to apples and compare the risk of heart complications requiring hospitalization (a fraction of the myocraditis and pericarditis cases caused by the vaccine) to the hospitalization rate of infection? You can normalize that by the 75% efficacy against Omicron if you want.
Pacing myself
The fact the CDC recognizes myocarditis results from infection of vaccination does not support your claim that it is a direct result of "spike protein saturating the body".

It is an immune response, not a direct effect of the protein. If it was a response to the protein, it wouldn't occur primarily after the second dose of Moderna, it would occur with equal likelihood after both first and second doses.
Capabilities model is not about "features" which might be deprecated, but more about "access to standard resources". Capabilities e.g. doesn't care that you are running version 3.1.73 of a certain dependency, it cares that you want to open a network connection to 123.76.34 or that you want /usr/bin/secret file.txt.
I've had such a better experience with Turo that I pretty much use it exclusively now. I get exactly the type of car I reserved, pay what was quoted, and often the owners are willing to pickup/dropoff at airport economy lots for an extra fee. The experience is 100x better than car rental companies.
https://en.wikipedia.org/wiki/Campaign_for_the_neologism_%22... "Santorum" may be an instructive example.
My thought about this one was, to obtain your own understanding of this world or everything, then make your own choices. It doesn't matter if you are mimetic or not, you are still living your own world, from the beginning to the end, isn't it?
Marissa Mayer excels at failing upwards.
> a part of their society that was particularly hard for the government to reach with containment action

I think there are parts of society like this almost everywhere, and that's why it's uncontainable once it hits a critical mass.

China is interesting. I guess they're doing it mostly through testing and restrictions that wouldn't work elsewhere? They have a good vaccination rate, but their vaccines aren't very effective. There's also North Korea; they claim zero cases. I imagine the real number is either surprisingly close or essentially 100%.
That's a horribly misleading comparison. Compare the risk of illness with severity similar to heart complications, or compare death rates. Don't compare one to the other.

The majority of myocarditis cases due to the vaccine don't even require hospitalization.
> But they're interesting because they are laws - because there's some structure there, because the same causes consistently have the same effects. Superdeterminism denies all that.

There can be structure without cause and effect. Take any static physics problem, for example a flexible sheet that’s stretched over some frame. Since there is no time dimension there is no cause and effect but at every point in the sheet there is structure (Poisson’s law).

Both QFT and GR are the same order in time and space dimensions. Now, time is special among the dimensions because of the second law of thermodynamics, but I still have this feeling that it’s our being part of the universe and our brains having sufficient complexity for self reference that causes the illusion of a linear flow of time, while in fact all time happened in one ‘instant’ and one of the requirements for our universe to exist is that it is self consistent (causing these weird conspirational coincidences).
Yeah, this is the simplest solution but it won't really stand the test of time either -- what if any one of the programs you have stop being developed or no longer can be compiled (zbarimg is the most obvious example -- I tried to get it working for Paperback but couldn't figure out how to make Java behave).
Ah, yes: Flash, Dart, game engines.

Great graphics, often great performance. Also, trouble with spell-checking, copy-paste, even selecting text. Often hard to make the layout responsive. Reading mode, screen readers need not remind of their existence. Hypertext links into that are also problematic.

It would be nice to be able to create a new, different platform for hypermedia documents right inside the legacy browser platform from 1996. Sadly, it's not yet there.
No idea what you are talking about. Pulseaudio nor systemd have wild crazy "it just stopped running" issues, like you suggest.

If something critical launched by your init system isnt coming up, I'd way way rather be using systemd. There's know wwys to inspect, check out what ran, what didnt, see what dependencies are failing. Check the common logging system. In the dark old days it was a nightmare of different daemons, each with their own custom init scripts, & little common reporting. Every problem was unique & required unique diagnosis.

I dont get what the complaints are. Things work great now. There's great diagnostic tools. Most of them with json/machine readible output. Distros sometimes do break various daemons but systemd and pulseaudio are pretty much bulletproof, and if they worked yesterday, i absolutely have faoth they'll work today. I detest so much that this kind of casual easy convenient Fear Uncertainty g Doubt shade throwing persists, that we so casually malign while making no assertions that could be refuted. There's a spectre of doubt that sabotages the good, that seeds disbelief, and it's never justified, never backed up by anything concrete or real or debateable: it's all just this haunting image that it's not going to work. It's seditious.
> When I worked for a company that required me to do on-call on holidays or weekends, I was given an extra vacation day in compensation even if I hadn’t actually done anything but triage.

This also occurs in the US and is more due to tech labor market tightness.
There's no "right to disconnect", it just makes companies come up with a formal policy. That policy can be: you can't.

Non-competes were never enforceable.

This is just BS toothless legislation from an unpopular corporatist government going into an election year pretending to be pro-worker.
Pigovian taxes are an example where altering price signals is a feature, not a bug: simultaneously disincentivize negative externalities, and act as wealth redistribution with dividends/UBI.

https://en.wikipedia.org/wiki/Pigovian_tax

https://en.wikipedia.org/wiki/Feebate
Please show me where exactly Apple advertises itself as porn-free in regards to iOS.
Perhaps some good news from a paper out of Japan: https://twitter.com/SystemsVirology/status/14747596949717278...
"The 6th preprint from G2P-Japan - #Omicron is less infectious and pathogenic than #Delta and even an early pandemic SARS-CoV-2 in infected hamster model."

Note: less infectious here means intra-cell, it's still more transmissible than Delta.

Another thread summarizing what this means: https://twitter.com/sailorrooscout/status/147509796693972172...
Interactive display of data sets. Mostly in finance, but I've worked in a few other industries where the same patterns apply. The focus of my development time is building out interactivity and optimizing data loading. Generating pages is the easy part.

As an example, I don't care about bundle size at all. A given app might have a hundred users all on desktop loading from an internal network. I will happily add a few MBs to the bundle if it increases the development velocity of my team.
This is Linq (and anonymous types). There are ports of Linq for other languages and a lot languages have similar features. It is nice though.
I recommend reading up on the work done by the latest Nobel price winners in Economics. But fair warning: they disagree with your assumptions/conclusions and have found clever ways to verify their assertions using real world data.
I don't think that's the right question to ask. Obviously my chances of surviving COVID would be higher with the vaccine than without. The real question is, which has an overall higher risk for someone of my age, sex, and health status, a COVID infection or the vaccine? I honestly don't know the answer to that question.
I'm a Norwegian that recently rented a car in the US, actually had a great experience. Thankfully, I had researched renting a car in the US, so I got a credit card before I left. A credit card is always smart to use while travelling anyway.

For some weird reason, I was charged way less than quoted at the reservation (~$2300 instead of ~$3700), seems like Alamo somehow forgot to charge the "Extra - Time & Distance" line on my reservation invoice. Can't really complain.
Me too. rss is the most important feature any website can offer. No rss means I don’t consume that webpage.
> It subsidizes the rest of Canada (the "have-nots"), but it can afford to do so.

How? I was wondering if you were talking about equalization payments, but it looks like Ontario is sending none and it used to receive payments from other provinces during most of the 2010's.

Also, many provinces may claim to be the California of Canada based on different aspects (laws, taxation, proximity to west coast, health system, climate, car-centricity - where Ontario would win, etc.), but this has the same value as cities claiming they are the new SV: not so much.
If I may do a hunch, since I don't see much information.

But I think older engineers could probably find a better/easier? Job in dev where memory isn't managed.

Eg. C++, hardware companies.

Also, I see multiple references to golang which seems good advice if you want to learn something new.
Wouldn't the fact that it's outcompeting Delta imply that there is some cross immunity?

I suppose there's some limited displacement effect e.g. if you have Omicron and self isolate you can't catch Delta during your self isolation period?
If (big if) I remember the Matt Levine stuff right this is kinda how Hertz came out relatively intact except with "spending a while in bankruptucy" in place of liquidity/capital.

Though I don't think most people expected it to end that way since the "used car prices rising" thing was unexpected and I suspect their meme stock adventures were a pretty essential unexpected bonus that helped as well.
It's hard to call the event as a whole exciting, especially from Game 7 on, but if you have any interest in chess I highly recommend watching a recap of Game 6—that one's going into the history books, I think. GothamChess made my favourite recap of it, but Agadmator's dry wit is always available if you find Levy annoying :)
I know the UK is tiny, but a few minutes sounds incredibly optimistic.
> whereupon they had managed to acquire a license for one of the biggest science-fiction properties in the world by employing a circuitous — not to say dubious — stratagem

Am I crazy or should there be an article about this and Star Fleet Battles??? This sounds like an impossible situation in todays protect the IP above all world.
The reason I have multiple "reservations" and only use one, is because it's quite honestly the only way to ensure I might have a chance at one of them having a car for me.

Literally yesterday I showed up at the airport, armed with two reservations for a mid-sized SUV. Neither company had one and both companies were the same parent. I ended up with a smaller car than I "reserved".

I would happily pay a non-refundable deposit at the time of making the "reservation" if that meant when I walked up to the counter, they would have the car I want.
This is all about antibody neutralization titers.

Researchers mix diluted blood plasma with viral samples, and then see whether it can grow in cell cultures. They figure out the concentration of plasma needed to neutralize all the virus.

2 doses of the vaccine produces plasma that can still neutralize the virus, but it requires 20x as much plasma on average. In turn, this means that the virus is more likely to be able to replicate and infect new cells before all the virus is neutralized.

However:

- There is still antibody efficacy against the virus, just not nearly as much.

- Memory B cells have a head-start at further developing specific immunity to new variants.

- This ignores the effect of T-cell mediated immunity.

- This mentions evidence that people who were previously infected and vaccinated have good neutralizing titers against Omicron.

- Other evidence suggests people who are boosted have much better neutralization titers against Omicron. That is, boosting doesn't just increase the number of antibodies, but increases the breadth of antibody protection.
No. 3rd dose Pfizer is not statistically significantly worse than infection for myocarditis.
One only uses Google services if one absolutely needs to. Google on the other hand never needs you. You are absolutely unnecessary and super easy to replace. Whichever you chose, the next search engine really needs our queries. If we give them enough they might be able to create a competitive product. If they do google will dramatically improve. I'm sure they have plenty of ideas, the incentive is just not there.
Interesting approach to bootstrapping a library ecosystem :) I wonder if this works on any nontrivial Python packages.
I tend to be a bit of a fence rider when it comes to these types of things.

Re: 5g we have so much accumulated knowledge and experience dealing with RF that the likelihood that we're going to be caught completely offguard and have no reasonable mitigation seems pretty low. At the same time, it's pretty obvious that our biology didn't have an opportunity to adapt to the types of energy we're putting into the environment and we'd be well served to keep an open mind about what the possible effects could be and how we would test and/or monitor for them.

There are other contemporary topics that suffer this same pathology. Reasonable questions raised in good faith get slapped down regularly and I think we pay a collective price for it. Of course some questions aren't reasonable and certainly not all are raised in good faith, so it's not exactly an easy problem to solve.
Most draws could be wins for black, give some to white. You don't need a point system to divide up the drawn outcomes
While tools can save us from stupid mistakes, some mistakes are so stupid that relying on tools to prevent them seems much more dangerous even. Log4j should not have been used by anyone, and certainly it should not have been extended and "improved" in an endless cascade of irresponsible additions, likely violating every principle of good practice, ever. I hope that this is what industry people take away from it, not that some magic language feature should have prevented it.
The trick with Ireland is to buy a policy ahead of time that covers the EU. If you neglect to do this, you will need to buy the overpriced policy at the counter.
Since the Golf is a hatchback and the Passat is a sedan, it is very surprising that the Passat would have more cargo capacity. Car and Driver currently shows 17.4 cubic feet for the Golf and 15.9 for the Passat, although perhaps they were inverted in a different model year.
Let's talk about the spectrum of harm related to crypto and blockchain
Capitalism, nepotism, public, private, insurance, nationalised healthcare ... the GP is saying that these are methods of dividing up available care, not methods for creating more available care.

X is the amount of medical care available

Y is the amount of medical care wanted

If Y < X there is no problem with any of the systems. And, obviously, a certain amount of inefficiency doesn't affect patient care. Plus, perhaps relevant today: when shit hits the fan we can scale up available care quickly.

If X > Y it doesn't matter which system you choose, someone will go without. You can change who goes without but you cannot fix the system by changing the method of dividing care.

Can things be somewhat improved with better organisation? Sure. Probably. But let's not overestimate it either. Let's take a dream scenario: optimal organisation can make 20% more care available. How much more care is wanted? I think we can safely say the US population wants 200% or more than the current system provides. Whilst nobody's opposed to improving organisations, it cannot fix the problem.

Fixing the problem is something you can only do by doubling the medical training available. That'll be a lot of extra dollars, none of which go anywhere near patient care for at least 10 years, so I would expect a lot of strong opposition from a lot of sides. But it's the only way to fix things.
> Not a lot because of privacy, something about that company ticks me off in terms of privacy.

Ditto, I just want something that isn't Google. That company has too many fingers in too many pies.

DuckDuckGo isn't more private. That is like when Google was serious about the Don't Be Evil slogan - there is nothing technically stopping them and sooner or later principles get worn down by reality (commercial, political or otherwise).

They are sincere today. Great, thanks. But there is nothing here to guarantee what they'll do in the future. I argue that people should use DuckDuckGo. But privacy combined with a public, ad-funded, search engine is just an unreasonable expectation. Anyone looking for that will be disappointed. But they are smaller and more focused - both of which are good if you want to be strategic about data leaking out.