skysight-inc/HackerNews huggingface dataset:
"Although the mechanisms for development of myocarditis are not clear, molecular mimicry between the spike protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and self-antigens, trigger of preexisting dysregulated immune pathways in certain individuals, immune response to mRNA, and activation of immunologic pathways, and dysregulated cytokine expression have been proposed."

https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA....

"An potential avenue for vaccine-associated myocarditis may be a nonspecific innate inflammatory immune response, or perhaps an interaction between the encoded viral spike protein of the mRNA and an as-yet undetermined cardiac protein. Studies have hypothesized that the antibodies generated in response to the mRNA spike protein may react with surface antibodies of the cardiomyocytes of susceptible hosts, provoking an inflammatory reaction and associated tissue damage."

https://www.tandfonline.com/doi/full/10.1080/14760584.2022.2...
If it were easy(-ier) to compare apples to apples with the “add ons” I wouldn’t care. But when one airline is $50 for a bag on a certain flight but $30 on others and another airline is $20, it’s hard to know which airfare is actually cheaper.
And this is one way they keep you married to them, with rewards and so on, by eliminating those for loyalty. Amex Platinum avoids most of this, but you can only get the nickel and dime repaid from one airline at a time.
Ideally, in a perfect world, the capabilities would themselves be something that could travel over an IPC channel, and in fact would have to travel over an IPC channel. The whole point of pervasive capabilities is that there aren't trivial escape hatches that every programmer uses at the drop of a hat. We don't need a new capabilities-based system for that, because we already have that. That's what we all use, every day.

On the one hand, I acknowledge the general impracticality of such an approach, but on the other I'm increasingly less convinced every year that anything less will ever be secure. And I also accept the corresponding implication that if programmers never do come to accept this sort of thing, we will never have secure code.
they'll say no, and chances are you already prepaid, so they'll take your payment and you'll be stuck somewhere for hours until everyone else is done
In Ontario? Are you sure? [0] [1] [2]

[0]: https://devrylaw.ca/renting-in-ontario-what-every-pet-owner-...
[1}: https://animaljustice.ca/blog/renting-with-pets-a-guide-to-o...
[2]: https://www.toronto.ca/community-people/housing-shelter/rent...
> If you see something marked 80% off look for a similar item that’s five times as expensive

When Facebook was first getting popular it triggered my bullshit detector.

I smelled bullshit because the underlying mechanism was social coercion to join, followed by social comparison to make everyone miserable.

It wasn't bullshit because it was bogus, it was bullshit because it stank.

My friends all have similar bullshit detectors for the spammy, the scammy and the coercive. If I knew how teach it, I'd be surprised if anybody who didn't already have it would even want to learn it.
I didn't know what the big deal was and thought it was silly until I actually lived in a place with a gas stove. Definitely motivated me to cook more. Induction also excellent. I'm not saying I physically can't cook with electric but it's unpleasant
What you need is not a capability safe language, but rather a tool to make application jails and similar systems more accessible.

Your os exists for a reason, let it handle the sandboxing for you, and not the language.

Otherwise you fall into troubles later with different sandboxing vulnerabilities in different compilers.

Have a codebase that compiles using deprecated features which are removed on language version 2.1 ?

“Tough luck, security patches only exists in 3.1 and above, guess you’ll have to stay unsafe”

Not to mention the pain it would bring on languages to backport safety features to older LTS releases of the compiler.

Just why?, let the os handle these things for you. It is called an operating system for a reason.

Log4j vulnerability was minimised in any organisation that restricts its applications network capability to whitelisted machines only, with the help of its OS features.

(Yes your application might need network access, so run it through a reverse proxy and filter the traffic based on strict set of rules)
Could anyone explain the significance of this finding?
In my opinion, there are three elements to any such automatic behavior.

1. How often does the behavior go wrong. Are there cases where the behavior goes wrong much more often than usual? You can also interpret this as "how often does the behavior break user expectations, even when it technically goes right".

2. If it goes wrong, how disastrous / irritating the consequences are (from the perspective of the user)?

3. How easy it is to recover from a wrong prediction.

If the product of those three factors get too high, the behavior is more irritating than helping.

Sometimes a suggestion is a much better option than invoking the behavior itself.
Just use the browser, first page only most of the time, if I feel bored then second page, very few times third page. More than 3/4 of the time I just read the first comment directly. I rarely read the original source unless it's really interesting or relevant.

I always wonder how the new submissions got promoted to the home page, as I seldom read the "News" category myself.
I thought so and didn't pursue it in school. After answering phones for a living for a while I changed my mind.
> The rental car industry, however, doesn't even try to manage the easily mitigated risks that are the entire reason reservation systems exist, because they take reservations but treat them as meaningless.

They obviously do not treat reservations as meaningless considering most people get a satisfactory experience most of the time.

I have rented a car at least 30 times off the top of my head, and a car I was happy with was available every time.

There are also 3 competing rental car companies, so if people really hated the car rental price to car rental experience ratio, surely one of them would have capitalized on it to gain market share.
It provides less return on investment... because of redlining. It's not rocket science. If you think redlining isn't a factor, the onus is on you to provide evidence to back up your argument that the almost 1:1 correspondence between redlining boundaries and disinvestment has nothing to do with redlining policy.
Human DNA contains roughly 3.2 billion nucleotides. A 3 GB string suggests an encoding with one byte per nucleotide.

I'm curious: since there are only 4 bases in DNA, for genomic data, this seems rather inefficient. Is there any advantage in encoding the DNA with two bits per nucleotide?

source for 3.2 billion: https://www.ncbi.nlm.nih.gov/books/NBK21134/#!po=0.485437
Thanks for the explanation.

> argues that the risk of myocarditis in under-40 males getting 2 shots is greater (perhaps much greater) than the risk of getting it from COVID

The way I read this is the risk of myocarditis is greater with vaccination, but this does not tell me about the overall risk of serious illness/death from Covid for vaxed VS unvaxed.

So - risk of myocarditis goes up - but is it still overall safer to be vaccinated for the under 40 males, or not?

Not pushing any angle or side here - just looking for clarity (as much as possible).
Wow. I only get the inner workings at a very basic, intuitive level, but it's really cool to see the progress of this and similar research. Congrats to the researchers.

It's awe-inspiring and even frightening at first, in the usual ways, but IMO it has a lot of long-term promise in other ways.

Spitballing: I like that this kind of result, which clearly calls into question the role or perception of physical identity, may eventually inform (or even necessitate?) the deconstruction of the physical "I" as a permission broker, and further open a many-to-many interface between the dimensions that underlay what we now think of as "self" and the true depth and variety within what we now think of as "individual humans who are not me". That opening process alone ought to be a huge jump for human development.

Right now we're each held, and holding ourselves, way too responsible for maintaining a singular subjective identity, looking at the aggregate. Not only does this compromise our outlook on others based on our subjective perception of the identity match, but it also compromises our ability to reliably consume and metabolize identity-construct-breaking information and experiences. And many of those things, when consumed without so many identity borders--so to speak--will end up being incredibly useful for individuals and group both.

Thanks for sharing op.
Some places will let you use a debit card, but want like a $2,500 deposit. Enterprise, I think?
Is everyone trolling me? I’m simply asking for a reputable source stating that google is censoring their search results.
They get enforced all the time, with sales, marketing, and executives.

I think that lower-on-the-totem-pole folks are unlikely to suffer, but HR departments love to have as much ammo as possible.
I use an RSS feed. No idea how posts are filtered or sorted because sometimes I see flagged posts (which I like to see). I have an account and usually only comment with replies, and rarely participate in conversations past a single reply (sorry) because I find otherwise I get too invested in them.

I spend more time reading the comments than the articles, half because I can learn more from the comments and half because I have a morbid love/hate fascination with the typical “facts over feelings” HN poster.
Took me four attempts but I also feel like I got lucky as in 2nd attempt I guessed 4/5 letters but all were in wrong order (1st attempt was all non-appearing letters). But that of course narrowed things down quite a lot..
Yeah but what's my risk of actually catching covid-19 vs. 100% if I just walk into my pharmacy and ask for the shot.
I've been reading it using the Feedly RSS reader app since a long time. Works like a charm.
A fun mashup between mastermind and a crossword
An animal study found that aspiration during injection could reduce the risk of vaccine induced myocarditis. It hasn't been reproduced in humans but this seems like something worthy of further research.

https://academic.oup.com/cid/advance-article/doi/10.1093/cid...
Cool game with a nice clean UI! There used to be a game show with a great name, Lingo[0], that combined this Mastermind-style word guessing with Bingo.

[0] https://en.wikipedia.org/wiki/Lingo_(American_game_show)
I use the RSS feed (with Miniflux as my RSS reader) and check for new entries at least daily.
Your suggested interpretation, that asking for advice means you're not an outlier on what you're asking about or you'd already know, strikes me as a very toxic ideal.

It's a story of my father. As far as I know, GF Gauss was the greatest mathematician since Archimedes and also a rather toxic person.

And there are a lot of ways you can interpret the quote. I think it's not so much an ideal but statement that actually society, even other prodigies, aren't necessarily going to support you going your own way. That isn't good imo but it's realistic. "Tough love" isn't necessarily the best teacher but it's certainly here.
like all things travel, my understanding is that renting a car isn't bad at all if you do it frequently enough.

and yeah, there's some residual pandemic chaos. last i read about renting a car in the pandemic was a very sad story about someone who was paid poverty wages to shuttle one way rentals around who caught the virus and died because their economic circumstance and job function did not allow them to shelter in place.

this piece is kinda cringey.
RA features pannus formation in joint spaces/articulate surfaces so I can see interface here with anything involving angiogenesis
The problem as I've experienced it is they hire you based on the code example from the interview and then the actual job requires you to know all the orchestration components (puppet, chef, kubernetes, package manager and system settings, etc) to bootstrap the virtual machine OS or cloud component that then will require you to know the particular OS distro CLI or cloud API to then run the code upon.

In my experience, I spend 80% of my time just figuring out how to get the code to run safely and properly and then chugging through the "stack" part of the full stack programmer before I'm even able to run my code at scale. The actual code itself tends to be simple. Sometimes already existing in a very fleshed out and optimized library, sometimes even core to the language itself.

It's really more endemic of more the prevalent problem that what HR thinks programming tends to not be what programmers actually do.
I'm glad you posted this. I felt like that kid that ate paste in school and was too afraid to post that it would have been better with pics.
I disagree. The social graph is the digital property of the user. If I export my twitter data and save it to my hard drive, Twitter cannot enforce the right to be forgotten. They are only expected to delete the user's data on servers they control.
You are misunderstanding what is meant by svadharma. Svadharma does not mean I do not work hauling trash or working in a field all day. It could mean exactly that. However given advances in technology, it could evolve to mean something different. It is not ones "ideal" - it is what one is naturally best at.
Can you define 'aspiration' in this case? The link is rather dense to the layperson.
An interesting fact about the rental industry learned during the pandemic was that the cars are all just bought on short term loans rather than being owned outright. The rental companies float the cost of the loan and it pay it off with the rental fees. Since they buy thousands of cars they get the lowest prices possible from manufactures, and they use this to their advantage to turn over their inventory on the used car market. During the pandemic this backfired on them since they weren’t able to rent the cars to pay the loans off and the car market also ground to a halt.
When we see men grow old and die at a certain time one after another, from century to century, we laugh at the elixir that promises to prolong life to a thousand years; and with equal justice may the lexicographer be derided, who being able to produce no example of a nation that has preserved their words and phrases from mutability, shall imagine that his dictionary can embalm his language, and secure it from corruption and decay, that it is in his power to change sublunary nature, and clear the world at once from folly, vanity, and affectation.

With this hope, however, academies have been instituted, to guard the avenues of their languages, to retain fugitives, and repulse intruders; but their vigilance and activity have hitherto been vain; sounds are too volatile and subtle for legal restraints; to enchain syllables, and to lash the wind, are equally the undertakings of pride, unwilling to measure its desires by its strength.
You don't, not without either resequencing it with another sequencing system or benchmarking the sequencer with a known sequence.
> not can most people afford a subsistence existence without soul crushing levels of anxiety from fear of accidentally becoming destitute

This is the human condition - through all the ages, most people would feel this way, and will continue to do so in the future. Until the day free energy and star trek level replicators exist, all wealth and all goods and services that people consume will need to be created by people. It's just the relative amounts that differ between the ages, but unfortunately, people don't compare themselves to people 100 years ago, they compare themselves to the jones.
Ask HN: What are good resources for following the latest R&D in computer vision?
Over the long run your risk of catching a SARS-CoV-2 infection approaches 100%. The virus can never be eradicated and we'll all be exposed to it occasionally. Vaccination — and other measures to strengthen your immune system — can reduce the risk of serious COVID-19 symptoms to fairly low levels.

https://www.medpagetoday.com/opinion/vinay-prasad/94646
We already know what are the effects of echo chambers.

Ps. HN is also an echo chamber but here readers are more keen to ask questions.
If rejecting apps that can lead to adult content (but not necessarily the main focus) seems to be the norm, how do reddit apps get around it?
We used Turo 3 times in 2 states and the results were always great. There are some quirks (California rentals were accompanied with a bigger service fees than the Colorado ones, for example).

I am sure like with Airbnb there are some horror stories, but haven’t heard of any
Frack this censorship.
> The center post was cut all the way through. The outer posts were each cut more than two thirds through. The great sign rested mostly on its own weight, precariously balanced. A south breeze would make it totter. A child could push it over. Within its gravitational time-space continuum, the billboard’s destiny was predetermined, beyond appeal. The arc of its return to earth could have been computed to within a tolerance of three millimeters. They savored the moment. The intrinsic virtues of free and worthy enterprise. The ghost of Sam Gompers smiled upon their labors.

“Push it over,” he said.

“You,” she said. “You did most of the work.”

“It’s your birthday.”

-Monkey Wrench Gang
The only way someone on HackerNews is going to get fired for being a member of the Glorious PC Gaming Master Race[1] is if they work for Sony or maybe Apple

1: https://youtu.be/P0dXtOVi2yo?t=52
I want to think it also handled congestion better. I wanna think I've experienced aread (airports? Downtown) where apparent thruput is better than I was used to when places were full of people.
Wow, I just got the Pfizer booster a few days ago and I'm an under-40 male who has previously had pericarditis... I was worried about the risk being greater than the reward for my age group but didn't have the age-stratified data to prove it. Kind of regretting it now, especially since I only got it at the urging of my wife. I just needlessly increased the odds of a giving myself a heart issue for absolutely no reason.

Edit: somebody else pointed out that the significantly elevated risk was only observed for Moderna (mRNA-1273). Pfizer (BNT162b2) only has a slightly elevated risk after the 2nd and 3rd doses. Looks like I'll be okay after all :)
Next, Apple refuses new Angry Birds update. Requests that birds be only "Mildly Annoyed".
Even with an index, counting the number of rows is an O(N) operation in most DBs.

Why?

1. DBs typically store data in some flavor of b-tree. Determining the number of elements in a sub-range of a b-tree (or any "standard" search tree) is O(N).

2. You can improve that to O(log N) if each b-tree node stores the size of its subtree. But this also increases the cost of add/remove operations.

3. And things get more complicated for DBs that support concurrent transactions, since the count is different for each transaction, depending on when it began running. You'd need something more complicated than just a size-of-subtree integer per node.

It's all doable, but isn't trivial and increases the cost of all add/remove operations.

There have been times where I really wished it existed, though... :-)
Billard-Ball Computer
Used car prices went up pretty dramatically during the pandemic, especially once new car supply chains started to get disrupted.

I’m sure the travel reduction was bad for them, but it’s not like they got stuck with a bunch of rotten tomatoes; the cars were still valuable.
> But that’s how the market works.

Yes, and that's the problem for programmers - those who'd prefer to solve problems better in the long run, which costs more in the short run.

In other words, there are programmers, who don't see a point in learning something which isn't really novel and isn't really progressive, but which is required to get a job. Some go for lower salaries, those are sometimes much lower - that's why people with high salaries e.g. from FAANG can be seen as delusional about their actual skills when compared with someone 1/5 of their salaries and stronger design abilities.

The problem - and the associated question - is what to do in the long-irrational market. One answer is known :) but it's not a particularly good one. Hope there are better ones -

> I chose some hot technologies that I could tolerate because I understood that’s just where it is

Sometimes market wants more than you could tolerate - emphasis on the last word.
The risk of serious COVID-19 symptoms are already at quite low levels in the < 40 male group.
I was building on your response to the GP. Instead of using -v to see files as they're being deleted, wouldn't it be safer to not use -f, which will not delete important files in the first place?

I see it countless times all over the Internet - everyone is constantly using -rf no matter the situation. The most common horror story in the article is from people using -rf and losing data. The whole point of -f is so normal usage (without -f) doesn't delete important files.
Thanks for sharing - that seems like an ambitious (and expensive?) project. Are you planning to do an all-up retrospective on it (not just the backup power but the entire site
and building)?
Granted Nepo self-destructed starting Game 8, so any psychological sub-currents paled in comparision with the on-the-board blunders. But I wouldn't go as far to call Classical chess "lame".
Why still use the term "reservation" then since that is not what it is? e.g., call it a "booking" or something...
Seconding this, but using Feedbin as my aggregator and Reeder on macOS and iOS.
In mountain locations, rain tends to run off the ground and into rivers as it rains. This depends on the region, but happens often in Spring/Fall.

Snowmelt, when the weather warms gradually, will slowly melt. It will seep into cracks and replenish underground water sources. It will also slowly replenish rivers often into (and sometimes throughout) the Summer.

So, a gradual snowmelt helps with the water cycle.[1] If warm weather comes fast, then the benefits over rain are diminished. Then less desirable effects like flooding can happen.

[1]https://www.usgs.gov/special-topics/water-science-school/sci...
if only they have some liquidity/capital to pay the loans during the initial stages of the pandemic, and last long enough to see the price of used cars sky rocket, they could've sold those cars at a profit to pay back the loans and still be operating (with a reduced fleet i guess?).
I used to say no. Up to a point when I rented a Qashqai in Belgium and caught a flat tire in London on Saturday. £280 and 6 hours later it was all sorted but that one tire was more expensive than the whole rental.

Or let me tell you about a van I once rented. Ended up stranded in a tunnel under Jena in Germany and ADAC came via Enterprise - €440 for towing on top of €680 rental.
It is apparently a means to double check and make sure you are injecting into a muscle and not into a blood vessel by seeing if you can draw blood at that site before you actually inject anything.

https://askinglot.com/what-does-it-mean-to-aspirate-an-injec...
Germanium Based Adaptive Transistors
Enterprise will accept a debit card and an up-to-date utility bill. But not at the airport, only in the retail locations not beside airports. At least officially. As the gp said, they can all relent and let you do it.
Oh right they censored things that are close to flat out lies.
Downvoted because, if there are many stories like this in "poorer" Spain (my home country), I'm sure there's a non-trivial amount of stories like this in any other richer European country:

https://www.reddit.com/r/SpainFIRE/