skysight-inc/HackerNews huggingface dataset:
Fluoxetine as well:
"Fluoxetine use is associated with improved survival of patients with COVID-19 pneumonia: A retrospective case-control study" – https://pubmed.ncbi.nlm.nih.gov/34856085/

"Do the Selective Serotonin Reuptake Inhibitor Antidepressants Fluoxetine and Fluvoxamine Reduce Mortality Among Patients With COVID-19?" – https://jamanetwork.com/journals/jamanetworkopen/fullarticle...

"Mortality Risk Among Patients With COVID-19 Prescribed Selective Serotonin Reuptake Inhibitor Antidepressants" – https://jamanetwork.com/journals/jamanetworkopen/fullarticle...

"Mortality risk is confirmed to be significantly decreased among patients with #COVID-19 prescribed SSRI antidepressants, and particularly #fluoxetine, and fluoxetine or #fluvoxamine, in a large (n>80,000) US observational study." – https://twitter.com/HoertelN/status/1460309793558646785?s=20

Dr. Farid Jalali's track record on accuracy of statements on the pathophysiology is excellent. Here's a thread that outlines how and why SSRIs work to reduce illness in COVID: https://twitter.com/farid__jalali/status/1440876997182300169

Platelets and serotonin are involved in the disease. Serotonin tends to cause inflammation, clotting, and vasoconstriction. A significant feature of COVID-19 is elevated plasma serotonin. (Here's an almost random source for this: https://twitter.com/ivanajpavlovic/status/146071264917663334... ... another: https://twitter.com/__ice9/status/1345194722055385091 ... these are tweets, yes, but they link to papers.) Platelets have serotonin transporters and serotonin receptors. SARS-CoV-2 does a lot of things; One of the things it does is that it kills platelets by inducing necroptosis (source: https://twitter.com/DrKoupenova/status/1418558896390688776?s... ). This releases the serotonin inside them, causing other platelets to clot. SSRIs block platelets from picking up serotonin produced and secreted by enterochromaffin cells in the digestive tract; This is the source of the platelets' serotonin payload (more here: https://en.wikipedia.org/wiki/Enterochromaffin_cell ). If an SSRI is taken early, platelets will have reduced serotonin payloads, which limits the serotonin-induced damage to the lung.

I had no idea about any of this until recently.

Another thing I had no idea about: Serotonin is metabolised by the lungs. https://twitter.com/ablative_sasha/status/144016208428566528... — and COVID-19 damages the lungs. It's a bad feedback loop involving way too much free serotonin.

There are other things at play but this is one of them. SSRIs work for a lot of patients, have a significant and confirmed benefit, and a mechanism of action that makes sense.

I've also seen pretty substantial claims / results that arginine, N-acetylcysteine, and melatonin seem to help. The best way to dig up those scientific results that do exist on it is actually to search Twitter for it. Try to find reliable-seeming scientists that are linking to actual papers and are careful in not suggesting too much.
I'm left wondering -- isn't this a toolkit/library issue?

I am a bit afraid of seeing gestures handled differently in multiple programs, like inertial scrolling, or pinch-to-zoom speed. At least gestures are always detected by libinput AFAIK, so there's that.

But instead of implementing this in every application, wouldn't it be nicer to implement the common part in a library and link that library to all app that require/want touch handling? This would provide homogeneous behavior, and would allow sharing configuration files.
Even TF 1 was just an extension of Google Brain: the project that took a datacenter of CPUs in Google to distinguish cats and dogs in Youtube videos with very high accuracy. I remember when Jeff Dean was talking about it the first time, it felt like magic (though it still feels like it, it’s just more optimized magic :) ).
It's less niche than I would have guessed--about 5% of industry revenue and about the same as CDs (which surprised me a bit given that I still sometimes buy CDs and haven't bough vinyl for decades). Still, that's revenue not listens or anything like that so that's still pretty much a rounding error.
That seems like it simply creates an evolutionary pressure against caring about the collective future.
Two Graphs Walk into a Bar
All of these things are adequately accounted for in my previous post except one which I find laughable every time I hear it, and provides sufficient evidence to me that you are an ideologue not concerned with realistic representations of history or current political events.

>Israeli apartheid state

Apartheid states do not let the oppressed class have massive representation in their representative government at all levels.

They do not have members of the oppressed class sit on the bench of the highest court in the land.

They do not mandate, at a federal level, that ALL state enterprise MUST have a member of the oppressed class on their board of directors.

They do not consistently have individuals from the oppressed class as cabinet members.

They do not have ambassadors belonging to the oppressed class.

They do not have members of the oppressed class as some of the highest ranking generals in their military, or as commanders of, hilariously, the border police.

Members of the oppressed class in apartheid states do not have the highest standard of living and quality of life compared to members of the same religious and ethnic groups in the region.

Apartheid states do not bend over backwards to accommodate, preserve, and enable the cultural and religious practices of the oppressed class, even when its members openly call for the genocide of the predominant ethnic group in the locale, refuse to participate in coalition governments, and reinforce sectarian, segregationist cultural policies and beliefs.

If you sincerely think Israel is an apartheid state, you are woefully uninformed, and a fool that has fallen for blatant propaganda.
The real fun is talking about other peoples' plans they aren't supposed to talk about. That's the best part about the internet -- there aren't any real consequences for doing so.
Build tiny games inside Jupyter Notebooks
I mentioned that. The problem with feather at the moment is readily writing metadata. I currently have to use a hacky workaround to write the metadata.
Siri uses it for answers to some questions (or used to). For example if you ask Siri what planes are overhead it used WolframAlpha to get that information.
Not mentioned here: the usage price for customised models is double the standard engine pricing. Whether you save on prompt tokens is something to consider carefully.
DHS Announces “Hack DHS” Bug Bounty Program
Maybe there's an inherent bias that people who prefer to hand write have better handwriting and therefore have a better experience. It's possible that most people with bad handwriting are more prone to want to type.
maybe you're just a passionate tweaker. the basic stuff I need for my workstation has to be configured on any OS - be it Windows, Linux or Mac. the more advanced stuff is mostly optional and I usually do it additionally on linux just because I can. so, I'd say this is a bit of an apple-pear-comparison.
This is fascinating, thank you. It seems like it might be worthwhile to learn Mathematica for use in coding interviews; many coding problems would be significantly simplified.
All the scary stuff that can go catastrophically long is within the next 40 days or so. However it'll take months to go through the calibration process, tweak the mirror positions, check out optics, etc
Made with ♥ in Colifornia
I very much appreciate the course you shared.

But I want to mention for everyone taking it: please also keep in mind "dumb" logical operators like OR, AND, NOT, and quotes that skip the NLP and use the exact text.

What frustrates me with Google Search is that it won't show me what I know precisely how to find. This is why I use Google less and go to specialized sites directly (Stack Exchange, Wikipedia, PubMed...).
interesting counter intuitive plot

methinks a microphone would often be better suited then, unless voice is also ruined by the disease
The US did have a single currency before 1914. But 1914 saw the creation of the Federal Reserve Bank system, which is a fiat money system. It was still backed by gold, but the events of 1929 proved that unworkable (the runs on the banks were the inevitable result), and FDR suspended that.
i had a job where i was the first staff, but when they started promoting everyone to staff cause every senior wanted a promotion, they had to create new levels of staff to differentiate
Fix the incentives, fix the world.
Using NLP to find the who/what/when/where of the Obama Presidency
If you didn't follow, significance of this release for most: Generics, finally!

Draft release notes are here: https://tip.golang.org/doc/go1.18
Sure. But notice that in the case of American black people’s plight, that’s the voice of the oppressor: “just be optimistic, work harder”. Meanwhile the oppressor cynically tightens the screws of oppression, e.g. by codifying racism into laws while making it illegal for black people to vote. So I would be careful insisting, again, that the victims of racism just choose positivity. Sure, there is a deep truth in that — ultimately you have to chose positivity to survive. But repeating that over and over is a cynical badge of racism.
Yeah, it's difficult to figure out how to act/think/feel on an individual level.

I recently read an interesting article related to this:

The Climate Crisis Is Worse Than You Can Imagine. Here’s What Happens If You Try.

https://www.propublica.org/article/the-climate-crisis-is-wor...
It's hard to say. At very least, the shading in the two pictures doesn't suggest that they're both presented in the same relative orientation.
They probably know that something like that would be games so hard that it would be impossible to filter out the good signal from bad.
Coaxial Goes to War
I admit #9 is fun but I try not to do too much #9, because there's a huge risk to doing too much of that: losing touch with what's important to the bottom line, and indirectly influencing all the other ICs that prototypes get you promoted. That's just not true in my company. My prototypes are usually for exploring something important to the company or validating a tech hypothesis of some sort. I try to spend more time writing production code where possible.
> Having a ship and a launcher capable of reaching the telescope is a bit different of being able to service it.

True. But generally when people bring up the statement that we can't service it, they usually back that up by citing the distance. There would still be a lot of hurdles to overcome, but none are insurmountable with relatively small investment.

All of that said, if Starship works, then the economics change drastically anyway. You could probably launch an entire fleet of less reliable, but much cheaper telescopes, for less than the cost of servicing.
Keepass X Development Stopped
I think GP is referring to earlier than that: when Covid was in China and was starting to blow up in Italy
I assume so, since they were mentioning Stockton and EPA.
Well John Romero got fired for slacking off on development of Quake 1 playing Doom deathmatches all the time. So I can imagine some devs love the games they make but probably not that many.
> A changing climate doesn't mean an unlivable earth.

Depends on which part you live in.

Unfortunately, the most populated regions are likely to be hit the hardest. And, really unfortunately, it is the developing world that will suffer the most.

Nations near the equator and island nations are going to have the hardest time with climate change.

I agree, climate change is unstoppable. Really, the focus now is doing what we can to decrease it's impact.
Not OP, but also have visual aphantasia. Not speaking for others, but for me personally, my mind is entirely auditory. I hear my thoughts as spoken words, and if I'm thinking about something complex, it resembles a crowd of chatter where I can focus in on certain conversations while tuning out the rest.

I majored in math, and when working with equations, I will literally hear in my head things like "eff of ex equals two ex squared plus ex plus five". If I'm multiplying 36 by 7 in my head, I will hear "seven times six is forty-two, hold the two, carry the four, seven times three plus four is twenty-five, the answer is two fifty two."

If that sounds like a difficult way to mentally calculate, I'll note that I'm not a good mental calculator. :) Abstract algebra and logic are much easier for me to grasp than fields requiring more visual intuition like geometry and topology.

Remembering things from a textbook, I usually just remember the content, although there are also cases too where I'll remember I got it from the textbook with the bicycle on the cover or some detail like that, not because I visually remember the bicycle, but rather because I've textually committed that book in my mind as "the book with the bicycle on the cover". If you asked me what color the bicycle is, I won't remember because I didn't note that in my mental description.
Designed by Abble in Califarnia
I’m not considering it if it’s not written in Rust.
Read this : https://www.bloomberg.com/news/features/2019-06-13/the-u-s-i...

> The NIH and the FBI are targeting ethnic Chinese scientists, including U.S. citizens, searching for a cancer cure. Here’s the first account of what happened to Xifeng Wu.

> Her resignation, and the departures in recent months of three other top Chinese American scientists from Houston-based MD Anderson, stem from a Trump administration drive to counter Chinese influence at U.S. research institutions. The aim is to stanch China’s well-documented and costly theft of U.S. innovation and know-how. The collateral effect, however, is to stymie basic science, the foundational research that underlies new medical treatments. Everything is commodified in the economic cold war with China, including the struggle to find a cure for cancer.

> Ways of working that have long been encouraged by the NIH and many research institutions, particularly MD Anderson, are now quasi-criminalized, with FBI agents reading private emails, stopping Chinese scientists at airports, and visiting people’s homes to ask about their loyalty.

Like in above case where the person is being entangled into an IRS tax evasion case, these people are being ethnically targeted, questions, harassed, their constitutional rights being trampled upon.
Please invest in the Meatverse (http://meatver.se), it's totally not a joke.
I highly doubt Dell or any of the other large system integrators will ever bring a truly "repairable" laptop to market, as like auto makers, they depend far too much on service / support revenue from their institutional customers to kill their golden goose by making their devices more easily user serviceable / repairable.

It's also utter nonsense for them to suggest that it would take them until 2030 to actually bring "some" of the ideas in their proof of concept to market, as if they truly wanted to produce such devices, they could have them out next year.

This is corporate greenwashing plain and simple.

Framework already has a far better product you can actually buy, and is a company built from the ground up around the principles of right to repair. If you truly care about right to repair, vote with your wallet and buy a Framebook. I'm certainly going to when they release their next generation of devices.
As for _Pragma(redefine_macro()) I don't want it to be a pragma, is the problem.

I want it to be either a compile-time operator like sizeof, or a Preprocessor Expression so it can be used correctly.

and it would eclipse #increment pretty easily; __redefine_macro(MacroNameToRedefine, ReplacementExpression)

if ReplacementExpression is a macro identifier it would be expanded first, so like `MacroToRedefine + 1` should work, I see no reason it shouldn't work.

maybe it would be ugly, but I think it would work.

----

My motivation is compile time registration for codecs, test suites, test cases being registered to suites, etc.
The price of gas recently increased sixfold here, so I just stopped heating my apartment. It's 12-13C in my living room and after a few weeks of discomfort this now feels like a comfortable temperature to me. (I might need to turn it on in a few weeks though, if it gets much colder. Even so, I've recalibrated my body to feel comfortable at a much lower temperature now, which is super cool!)

I did this due to some combination of poverty and stoicism, but it made me realize how much gas I was burning before without really needing it. (I always felt a little bad using so much of a nonrenewable resource.)

Sure I like it when it's warm inside, but really it's an unnecessary luxury we've all gotten used to. (At least for the young and healthy -- I hear for older people cold temperatures can be harmful?)

Worth noting though that I do get some heat through my walls from the neighbors -- if we all turned off the heat it would be a lot colder ;) Even so I reckon the usage could be cut by a good deal (40-50%?) without any serious issues, it would just be a very unpopular proposal.
Those diseases could be (mostly) eradicated because they have incredibly effective vaccines - the CDC quotes 95% for smallpox, 97% for measles, 99-100% for polio. No currently known Covid vaccine is that effective and there's no obvious reason to expect future ones will be.
>Why shouldn't Linux be for everybody, usable on every type of device?

It is, but you often have the effort to put into it. Windows isn't usable for everyone, but that doesn't make me elitist, OSX is hard for others, but I don't see that being a problem. Some people can't do everything you do, and there are differences in our abilities. If you expect everything to be easy, and people not willing to put in work to have a functional OS, you should not expect them to use linux, it offers no benefits to most users, its made by hackers to hack on, Android is linux for everyone, and even then they find it hard. Don't expect people to run when they can't crawl.

>Why should we need to rely on proprietary software for our day-to-day tasks?

Because the free stuff sucks, GIMP still sucks. They stuck to having 3 windows open forever, GNOME doesn't like being configured, GTK always breaks stuff, and I just want stuff that "just works". When FOSS does it well like KDE being better than Windows's UI, or Firefox being better than IE6 I will choose it. I don't pick based on their principals, I just want good software, and like most people I am willing to pay for quality. I refuse to use a pinephone out of principal, I refuse to make my life hell.
Absolutely locked up my machine in Firefox. No thanks.
That's a great idea - do you mind sharing your flashcard deck?
A few years ago it was the only tool I could find that could answer questions like "show me every college within 100 km of this point".

I haven't needed to do anything like that since. But it is yet another example of how I think Google maps and similar are weak junk only good for finding coffee shops.
No one replying has a "serious level of knowledge", so instead, turn to sources that do (or report serious sources!)

https://www.smithsonianmag.com/science-nature/how-viruses-ev...

https://pubmed.ncbi.nlm.nih.gov/30734920/ (really good one)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255208/

In short, we don't know and won't know until this is all "over" a few years in the future, at least.
US Department of Energy Seeks Input on Creation of Haleu Availability Program
Again, illustrating my point.

You’re essentially trying to threaten me if I dare disagree with your position. This is what I mean by jump the shark.
As soon as good AR glasses come out though, Black Mirror's an instruction manual on what app to write.
OS currency is a big deal for us in Banking. The Cloud vendor maintaining the OS currency and patches will save us so much headaches. Its entirely possible that version x of a custom application requires version q of the OS but the Cloud vendor is mandating version r of the OS. In this case we get to go back to business and app teams and force them to either upgrade their software or containerized or retire their app. Without this stick, we would be stuck with apps untouched , not- maintained and vulnerable forever.
> how do you all cope with this?

The same way I cope with change in general: by adapting. Which is the approach I think we should be taking in general as a society towards climate change.

> I'm addicted to my comfortable, wealthy lifestyle as a software engineer and I'm ashamed of it.

You shouldn't be. Most people in the world demonstrate by the choices they make that they prefer a more wealthy lifestyle to a less wealthy one. There are people who don't, but even most of them depend for some essential functions on technology that is only possible in a wealthy society. (Anyone who really doesn't depend on technology for anything won't be posting here or reading posts here anyway.)

Human activities can certainly affect the environment, and not just the climate. IMO the hysteria over climate change has had the unfortunate effect of putting many other more pressing environmental issues on the back burner. We should be good stewards of the environment, but that requires being as objective as we can about how much priority issues actually deserve, and also requires recognizing that the best way to fix environmental issues in general is to create more wealth. The wealthier the world is, the cheaper fixing up the environment becomes in comparison.
So is my current terminal app, which clocks in at 250 kilobyte. And its memory and CPU footprint is so low, I can't find it in htop without filtering.
Location: Poland, Europe
Remote: Yes (EST/PST timezones OK)
Willing to relocate: No

Technologies:
* java, kotlin, groovy, spring, spring boot, activemq,ajax,angular,apache,aws,boot,cloud,ddd,docker,dojo,ejb,ejb3,git,gradle,hibernate,jboss,jdbc,jms,jpa,jsf,junit,kafka,kubernates,maven,microservices,mssql,oracle,react,scrum,selenium,servlet,sql,sqlite,svn,tapestry,tdd,webdriver,ws

Email: mmarkowski-angel@protonmail.com

I am a Backend Java Engineer with 12 years of commercial experience (esp. FinTech, Healthcare) in prototyping, MVP, backend development as well as maintenance and DevOps. Great communication skills, Startup experience, team leadership, passionate about programming, self starter, OK with freelance/consulting as well as full time work.
it may be one of three listed platforms, but this product seems pretty clearly targeted at windows users, so that will not account for anything close to one third of the potential users.

agreed that you were mis quoted, but i don't think they were wrong.
To be clear I did not mean it as a dig on your service! It's a really cool idea, sorry for not saying it before. It was just a perfect irony.

You could also do some heuristics like not accepting emails with excessive HTML. Though I'm not sure how much it'd work, since you already require confirmation so presumably the spammers actually have someone authorizing the publication. (I didn't test your flow since I have nothing that warrants posting to say)
The vaccine was initially sold as the tool to end the pandemic and get life
back to 'normal'. The narrative has evolved to suit the deficiencies of the vaccine
and keep profits from sinking.