skysight-inc/HackerNews huggingface dataset:
Not directly an answer to your question, but if you're not already aware of it, another thing that might be worth pursuing in parallel is having your doctor refer you to the Undiagnosed Disease Network, if the case meets the criteria for that [1].

Another avenue might be a crowdsourced rare disease research organization like [2]

I have no relation to any of the above but read a book about the UDN that may be of interest to you: [3]

[1] https://undiagnosed.hms.harvard.edu/apply/

[2] https://www.researchtothepeople.org/

[3] https://www.goodreads.com/en/book/show/53317420-the-genome-o...
have fun staying poor
Are old people with pre-existing conditions consuming 90% of ICU resources in some areas? When comparing resource utilization of getting a preventative vaccine with the resource utilization required from a 4 - 6 week stay in the hospital, and that the health system does not typically need to run at overcapacity except when overrun by unvaccinated patients, we can confidently blame the unvaccinated for straining healthcare resources by ending up in the hospital for a completely preventable disease. It would not be an issue if more people were vaccinated, and we only needed to treat breakthrough cases. The hospitals should not need to grow larger when there is a highly effective preventative available right now for free.

When in a time of a pandemic, with a deadly and highly contagious disease, refusing the vaccine is like refusing the uber or taxi offered to you for free, and insisting on taking your car instead. They are absolutely not unwitting. They are absolutely making a conscious choice to purposefully increase their risk, and the risk of others around them. You like to talk about their personal liberties, but not about their personal responsibilities for the choices they've made.
I dont automate CI/CD because I'd rather be sword-fighting on roller chairs, I automate because I value the cost of my own work time and truly would rather spend it on a more interesting problem. (To say nothing of the fact its all too easy to make mistakes where processes arent automated, and I dont enjoy making mistakes)

I dont disagree with your observations, just saying "productivity" gain is pretty far down the list of benefits to me personally
Non-x86 architectures are vaguely supported, however the key thing here is that it needs a scheduler model i.e. architecture isn't enough. I think the basics of in-order target support is being worked on (possibly merged, haven't been keeping up to date)

https://reviews.llvm.org/D94928

Other tools to do this exist (or have existed, Intel IACA rest in peace), but I'm slightly sceptical how useful they are in practice.

They can't model anything transient in the processor (can't easily, at least) like branch prediction and the memory hierarchy. That and there's only so much detail one can fit inside a model.
> maybe its all just people finding ways to hijack and abuse basic human neural mechanisms in order to generate revenue off of others.

I'm not going to let your exceptionally cynical content hijack my neural mechanisms!
Just resin coated in silver, although you’ll need a 3d printer with extraordinary resolution.
> Fastly's post (original topic) expands on why the test is poor in other ways worth reading over again.

Do you want to highlight any of those? RTT is mentioned in a post from "Cloudflare Research" which was just shared by their head of research [1].

> Beyond just those points, the whole Cloudflare blog post reads like an attempt at a performance sales kill sheet. (In other words, their sales may point to this as to why folks should choose Cloudflare Workers over Fastly Compute@Edge.)

There is nothing wrong with advertising. This comment section is just about keeping them honest.

[1] https://twitter.com/grittygrease/status/1468016152752361472
Every court has a clerk's office that handles the records. You generally have to go in person. For court transcripts, you may have to pay to have them made (they may record the proceedings and make the transcript on demand).
Let's say everyone on the planet is Ethereum enabled tomorrow. What is the business case for the winery to use it in your example? I get that Ethereum or any other crypto can be another payment option for their customers. Beyond that what use does a winery have for a programmable substrate underlying its transactions with customers or suppliers? I'm not saying there is none but if you're going to rip on HN users, frankly it's hard to parse what this language even means.
The Page Info I see says this:

> article:published-time 2016-10-28T11:40:06+00:00

which is well into the era of 64-bit code.
I was surprised at how hostile Canadian cities are for accessibility, until I found out that there's no equivalent to the ADA[0] over there. Something like half the subway stations in Toronto are simply impossible to use for someone in a wheelchair for instance.

I wonder if this ban isn't to give the impression that those in charge are "doing something". It's cheaper to ban a few startups than it is to retrofit stations were engineered to keep handicapped people away.

[0] https://en.wikipedia.org/wiki/Americans_with_Disabilities_Ac...
Whenever I see a mountain lately, I run to the top of it so I can sing the praises of my 31.5-inch Dell UP3218K 7680 x 4320 8K computer monitor.

I'm a software engineer by trade, so I am looking at code all day long, plus lots of web searching and other text-heavy computer use.

I thought the LG UltraFine 5K and Apple XDR Pro Display were "good enough for my eyes" since I couldn't see the pixels.

Compared to the XDR (same size) the text on the 8K screen is WAY WAY sharper. Even though I thought the 218ppi XDR (basically same as 27" 5K monitor) was crisp before I saw the 280ppi Dell, I immediately realized it totally wasn't.

I can feel the eye strain difference, too. The lower res monitor is just fuzzy. I can't see the pixels individually, but when I slide my chair from the Linux box with the 8K to my Mac with the lower-PPI 5K display (sold the pricy XDR immediately after seeing the 8K panel next to it), I can see the fuzziness at the edges of text.

So I am kicking myself for not getting this much earlier. The Dell is ancient, came out years ago and requires 2 DisplayPort cables.

I am not an ophthalmologist so I can't speak to what this will mean for my long-term eye health, but I can say that my eyes are significantly less tired at the end of the day, and I never have to use the computer glasses I bought a couple years ago (the kind that are like reading glasses but for a little farther distance). I was using those a lot before, since my middle-aged eyes are indeed deteriorating.

BTW, for a few weeks I had the 8K Dell and the 6K Apple displays side by side. They are the same physical size, and the text was just about exactly the same size. Most of the people I asked to come look at them agreed the 8K display "looked better" or "looked sharper".

There is also the factor of Linux vs Mac font rendering. I am using Pop OS with 200% UI scaling on the Linux. I kinda wanted to compare them side by side in macOS, but I don't have any Macs that can drive the weird 2-cable Dell. So that could also be part of the difference, but I think it is basically just that 280ppi is way, way better than 208ppi.
The risk of the money being fraudulently taken back is close to zero. If you are worrying about that happening, then you are either a fraudster yourself, or just being paranoid. There is no major benefit to not having this.

On the other hand, if a crypto transaction has any errors, the money is instantly lost forever, and nobody can help you.

There is no upside to that at all.
Bloatware is devouring the world!
Their secret sauce is that they have spent a lot of time and money innovating on how to not kill battery life. The app polls users for location on different intervals. Periodically if no one has the app open, but if someone opens the app it will start polling people whose locations are available to them. Find My Friends has a similar approach, although it ONLY polls when someone has Find My Friends open that has a shared location available, and it doesn't store the data (last I checked).
> Motte and Bailey is shifting positions on the same issue.

The issue in this case is the avowed principle, on which they have two distinct positions, while pretending they're the same.

That said, I don't disagree that you can find hypocrisy on the left as well. Just look at housing in California. You could make housing cheaper, drastically benefiting the poor and working class, through either zoning deregulation or massive public housing investment or both, but the Dems there choose largely to do neither.
Surprised actually this doesn't exist in a more general sense -- just X of N decryption of arbitrary files. Could be your private key recovery, or just mundane corporate documents with provable "two man rule"
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I was under the impression the paper by Jaffe[1] showed the negative energy explanation[2] was not physical, but totally not my field.

[1]: https://arxiv.org/abs/hep-th/0503158v1

[2]: https://en.wikipedia.org/wiki/Casimir_effect#Relativistic_va...
Sovereign immunity means they cannot sue the Myanmar government.
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Specifically, Boston has a large number of biotech firms and colleges who have the equipment to do PCR testing, as well as the know how to run them.
Pro-Trump counties now have far higher Covid death rates due to misinformation
Log-Structured Protocols in Delos
Someone else wasn't wrong.
An Alcubierre drive is a theorized device for faster-than-light travel that kind of doesn't technically violate any known physical laws. Instead of accelerating a ship beyond the speed of light (which we think should take infinite energy), it instead manipulates spacetime itself (contracting the spacetime in front of the ship and expanding the spacetime behind the ship) in order to achieve apparent faster-than-light travel. But just because it can be theorized doesn't mean that such a drive is possible to build, particularly with regard to the requirement for negative energy density. This paper appears to suggest that one candidate for providing negative energy density might be achievable.
Looks like Arch Linux is building it themselves with --with-wasi-sysroot. The changes they made to the build script for the 95.0 release are pretty instructive: https://github.com/archlinux/svntogit-packages/commit/532ac4...

Hopefully Fedora manage to implement this to their satisfaction in the near future, although requiring extremely recent releases of build tools might be a blocker for some distros.
Well, if you believed as the author did that arguments are always pushed onto the stack, you are pretty ignorant--most major architectures these days don't use the stack for arguments, at least not for the first several arguments.

(Semi-random tangent: the hardest bug I ever had the pleasure of debugging was when I discovered that the PLT glue code to load an entry into the PLT was unexpectedly clobbering a register that the calling convention said needed to be preserved. By very, very careful using non-default calling conventions across shared object boundaries!)
+1 here. The base Galaxy Buds destroy the Airpods in sound quality any day of the week, and they're mega-comfortable too. I don't use mine anymore, but I loved it when I did.
Sandi Toksvig is an impressively good replacement as well, which for me is surprising because I'm a huge Stephen Fry fan and expected the show to go to hell without him.
> Viral load, also known as viral burden, is a numerical expression of the quantity of virus in a given volume of fluid

Yes, in a specific fluid. Grandparent doesn't like viral load data coming from upper respiratory swabs-- preferring some kind of "higher systemic load" number.

Well, there's no magical "real systemic" load. You can measure it in the nose; you can measure it (sometimes) in the bloodstream (but this is sporadic and small even in severe cases, though it has prognostic value in critical care). You can measure it in feces, etc.
Is the notion that we could create a craft that travels faster than the speed of flight more absurd, less absurd, or equally as absurd as the notion that we could create a perpetual motion machine?
There were times when physics PhDs would chuckle and say absurd about going faster than sound. The equations that we had back then also predicted all kind of infinities in pressure, etc.
Up to and including companies of 100,000 staff, to my current employer of < 100.

At around ~1,000 staff though you quickly lose "insight" into platform security as it's delegated out to sub-orgs within a larger organisation.

Though I've not worked at any FAANG companies where I'd hope security is... erm, of a certain 'maturity'. E.g. Google and BeyondCorp.

But I've no desire to rehash leet code exams or get back in that space so likely will never go there :).
Education alone can’t solve the poverty problem
Maybe this is why they are looking for five Retention Managers... one a Senior...
I upvoted Kenton’s post. He’s the reason Workers exists. Surprised anyone worried about him commenting. I’d only be worried if I were a competitor who pissed him off by publishing BS stats. I’d imagine there’ll be an incredibly thorough and totally unimpeachable benchmarking study that comes out of this. And, anywhere we’re not the fastest, we soon will be. Game on.
Not a physicist, but some friends who are almost-barely physicists have pointed out that the concept of worldline numerics comes from string theory, which itself may or may not be generally bogus depending on who you're asking.
Yes, we have that feature too. So you think I should just focus on that idea only?
The one true language: Threaded INTERCAL.
This is very interesting. The article points out twice that there is no evidence it's causal, but does proposr some potential causal mechanisms, all told a pretty reasonable summary of the finding.

I'm curious to know if there is any info related to alzheimers and sex drive. The 70% is based on chance developing alzheimers in the next six years, I wonder if there is any relation between a profile who would seek Viagra - I guess that would be people interested in sex, have an available partner, but having trouble - and one who would be less likely to get alzheimers soon.
I don't even get why Alcubierre drives are called like that - this very concept was described in great detail in a rare soviet space opera "Humans as gods" [1] by Sergey Snegov written in 1960s.

[1]: https://en.m.wikipedia.org/wiki/Humans_as_Gods
> Crypto proponents are in favor of there being no technical restrictions that prevent such content being posted

This is precisely why they'll fail (aside from technological issues): the rank and file person on the internet does NOT want a Wild West when they go to visit a news feed. Hell, the average person doesn't even really like curated content. They want a chronological list of things they decide to be relevant and nothing else. Just look at all the complaining every time Instatwitter changes an algorithm and hides the method for sorting by most recent.

And what they don't know yet is that all these big companies, if they use this technology, they're going to use them in very focused ways to reward people and prevent them from abandoning their platforms. Because "free" has many meanings, but none of them are inherently exclusionary from corporate competition.
From my current understanding, it’s less absurd. Again the pedantic ones would say this is still not FTL but again to them who cares? We are not breaking laws of physics and we get from point a to point b fast.
Intel to List Shares in Mobileye Unit
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That is really pretty and I'm happy you shared it with us.

I wonder how much compute would be required to have it map an image or short video clip to always be level, regardless of cube orientation or angle of the faces?
Internet addiction: The emergence of a new clinical disorder (1996) [pdf]
Is there a Kubernetes Helm chart to deploy Postal?
China to upgrade mainstream RISC-V chips every six months
There's a lot of science that was discovered by people who had the ability to devote their time and energy to discovery for it's own sake.

There's no reason academia and research labs should have a monopoly on such opportunities these days. All it really takes is burn time, dedication and intelligence.

Why don't some of us just spend our time on these kinds of things? Far as I can tell, the equipment expense is well within the budget of a co-op of well paid tech folks.
The question is "who shares more details on pricing", not "who has more unpriced features".

https://www.cloudflare.com/plans/
Well, photolithography's been done in a garage before. Doesn't seem impossible.
>> But as long as we're already mud slinging

Strange statement. Didn't Cloudflare start the mud slinging?

I have no shares in this. But Cloudflare publishing questionable benchmarks with competing services while prohibiting competitors publishing benchmarks with Cloudflare services is certainly not fair play. Reminds me of Oracle.
"Form" is not only the package name of the tool but also a general term in Lisp that refers to S-expressions in the code.
Former jailbreaker here, but still holding strong on a jailbreakable iOS version (14.3).

I stopped using a jailbroken phone mainly because it was getting more and more difficult to circumvent banking app security, and it seemed like every payment-related app wants to include some form of jailbreak detection these days.
I bet there's now a bunch of trawling popular golang repos for: [0] == '\0' or similar.
Seems to be working for me (in Australia).
Folks have been testing wastewater for legal and illegal drugs for years (https://score-cost.eu has an interesting report if you're interested).

There's been talk amongst Police Departments in whether investing in wide scale wastewater monitoring could help locate drug dealers/labs. Personally, I think this is a huge invasion of privacy, but since wastewater is a "public good" police currently can do whatever they want with it (source: I work in a wastewater testing facility).
A significant goal of wastewater treatment is reducing or eliminating pathogenic load. For a methods overview, see: https://www.filtsep.com/water-and-wastewater/features/pathog...

This paper discusses treatment and emergent pathogens:

"The Role of Wastewater Treatment in Protecting Water Supplies Against Emerging Pathogens"

https://www.jstor.org/stable/23803199

I thought direct chlorination played a larger role, it seems it doesn't.

(Heavy chlorination of water does result in post-treatment chlorine compounds being present, these are themselves an environmental concern. The bulk of the chlorine evaporates or is reacted relatively quickly. Chlorine also negatively impacts "digestors" which process residual organic matter in wastewater.)

UV, oxygenation, sunlight, filtration, and dilution are all utilised as well.

Viruses tend not to survive long periods of environmental exposure outside a host in most circumstances, though I'm not knowledgeable on specifics or exceptions.
Apple AirTags Are Now Being Used to Steal Cars in Canada
It is extremely helpful to be able to estimate performance without building out a whole system. For instance 10ms vs 100ms vs 1s latency makes a world of difference as far as what is possible and what component might be the bottleneck. Though, I agree that the “horse race” between several highly optimized and broadly similar libraries may be far less interesting
Which condition is this?
Absolutely. I’m a biologist myself but I NOped out of academia with my PhD. Just making my money now before I establish my own garage lab to study connectomics.
As far as I could tell, 14 is the maximum, since that's the number of times your code gets injected. I didn't quite figure out why they called it the 21 vector challenge, other than a reference to the current year?

If you're allowed to execute code more than once per injection site, I think the scoring would rapidly become ill-defined...
The fact that a lead engineer and CEO took the time to respond here is clarity not a flamewar.

edit maybe I'm wrong,

https://news.ycombinator.com/item?id=29469174
> it opened my eyes to some major issues when the PG optimizer doesn't get a query right you have no escape hatch.

For me the biggest issue with that is that the optimizer decision can change basically at any time. If the stats start preferring one index over the other at 2am, you can't just say "no, trust me, use this one instead" - you have to find out exactly which value crossed some threshold and tweak the stats to restore the previous behaviour.

> it wasn't obvious to me if this is very common and how often you _have_ to tell MySQL what index to use because the optimizer misses it...

I'm not sure how representative my sample is, but in the last 20 years, I've seen a hint used two times and one of them was an app bug (the forced index was not better, the order of columns in it should've been reversed and the hint removed). But I haven't worked with super-complicated reporting queries.
Out of curiosity, which features are you referring to? My impression (joined < 1 year ago) is that the vast majority of products are available to free customers (albeit with smaller limits perhaps) while the gap between self-service paid accounts and enterprise is smaller still.