skysight-inc/HackerNews huggingface dataset:
Yes. I think the device used is a bit more sophisticated than simply obtaining the cycle number where it crosses the threshold. There's a variation of PCR called quantitative PCR (qPCR) that measures a fluorescence signal more or less continuously and the growth rate allows one to work backwards to the initial count. Here's a basic description from the maker of the device they used (Taqman) https://www.thermofisher.com/blog/ask-a-scientist/what-is-qp...
Is this surprising to absolutely anybody? I'm curious. I follow a lot of content creators on YouTube - I watch way too much YouTube in a single day, and I thought this was just common knowledge.

The YouTube copyright system is broken. Completely. Content creators have been battling this for a while. A loosing battle - because YouTube has been doing nothing to fix it.
Advanced C: The UB and optimizations that trick good programmers
Yes, I am still talk about that blind spot.

What I mean is that people don't care for other blind spots or risk of kids running from behind a car.

It means they haven't "forgot" about the A-pillar blind spot. They just don't care.

> a) Your mirrors are supposed to be pointed at the road behind you, not showing you the side of your car.

Now, they do not. The rear view mirror is supposed to be pointed at the road behind you. Side mirrors serve vital function of filling your blindspot formed between the cone of rear view mirror and your peripheral vision.

This is different in a truck. In a truck you don't have rear view mirror and so your side mirrors actually need to point at the road behind. But you will also notice they are much larger for that reason.

Here in Poland it is illegal to drive your car with the vision through the rear view mirror obstructed. That only makes sense if the side mirrors are not supposed to cover the road behind you.

> b) How are you able to tell what their mirrors are pointed at from the outside?

How to tell without offending you... it is called physics.

The mirror works reversibly. If I can see their face in their mirror it means they can see my face in the mirror -- a face in the car directly behind their car.
There were many. They just weren't particularly good UX wise. Some of them were great / good / fine soundwise, but the UX typically sucked.
This is really nice! Is there anything similar in (Neo)?vim?
You must be using an archaic pronunciation, like when you say ask instead of aks.
Battery?
> That is an incredibly naive view of the world.

It's not. When you silence ignorant people, they get more radical and more willing to do things they otherwise wouldn't because they no longer have an outlet. Silencing a neo nazi forum increases the likelihood for "those f'ing j*s shut us down, let's get em!" behavior. And even if that didn't happen, it's far easier for law enforcement to surveil people planning violence if it's out in the open.

> Just look at QAnon for another example.

I know multiple people who went down this rabbit hole (one of them is still down it). And what I said above applied exactly when they started getting booted off social networks. Before then there was no plotting or aggressive stance. They just thought they were "on to something."
Let's take a moment to thank gorhill for his work!

Thank you!
Inflation does enter the conversation for investors. Risk-free real rate is -450bps, equity risk premium is historically 200-300bps so implied return for SPX is -150bps.

One of the arguments is that things like tech will protect value because they have pricing power/growth or something similar, but this hasn't worked if you are starting from high valuations because inflation tends to change the cost of equity quite significantly, as the original calculation showed (to be clear, the point is that the price for bonds and/or equity is very wrong)...valuations are very high, a financial shock when you starting from a valuation that implies equities have no risk will be severe.

I am not saying that anyone should do or not do any specific thing but inflation, if it persists, will impact everyone because the effect of inflation is not limited to prices rising. For example, inflation might not impact you but a risk-free rate of 10% might.
> The case tried in federal court in Miami was highly technical, with the jury listening to explanations of the intricate workings of cryptocurrencies as well as the murky origins of how Bitcoin came to be.

Where would one go to read the court proceedings? I’d like to know how this was all laid out to the jury.
>> makes the language better

> Do you plan to resume using the word "hôtel"? ("The French spelling, with the circumflex, was also used in English, but is now rare" - https://en.wikipedia.org/wiki/Hotel .)

How does that actually archaic spelling of "hotel" help make the language better? The diaresis helps disambiguate the words coop (housing for chickens) and coöp (a business built as a coöperative). That's just one example.

The rest of your post has some interesting points, though it's most interesting to me here because it seems to directly conflict with the "old" sense of the word "archaic" from the above discussion if it's a 19th/20th Century invention. It would imply to me the use of the word "archaic" is a bad editorial choice in the Wikipedia article and its primary sources on that word choice maybe not be the most reliable. (Of two citations, the one that actually uses the word "archaic" is a personal blog post, versus the Fowler's Modern English citation simply says "often dropped" and doesn't editorialize but does "blame" "often not on modern keyboards".)
Most definitely they existed (even the quote admits to that), but unlike other areas, I do not see other manufacturers following Apple in either functionality or aesthetics (compare what happened with slate smartphones); and I most definitely do not even see Apple leading in any metric, specially not in 2016.
I wish I could find a home executable mold spore test procedure that will give me spore counts by types. Most of the consumer tests are next to worthless. I think all I need is a fan with known volume of flow through some .3 micron filter paper, then I can check it under a microscope (guess the filter paper could use a grid, unless my hemocytomer will cast shadow through the paper.
> Cloudflare not allowing benchmarks in their TOS is very sketchy, that puts them in the same tier as Oracle.

There's a non-sketchy way for a company to do that kind of thing which avoids putting them in Oracle territory. Simply require that anyone publishing benchmarks (1) publish complete configuration information sufficient to allow the company and other interested third parties to reproduce the benchmarks, and (2) allows benchmarking of their products that they are benchmarking against yours under similar terms.

It is nicer of course to not have any benchmarking restrictions, but if you do that you are putting yourself at a disadvantage to companies like Oracle. They can benchmark against you put you can't do the same against them.

Once one important player in a market goes down the Oracle route others tend to follow. But if they aren't asses they will follow with the kind of restriction with reciprocity I outlined above instead of an Oracle-like restriction.
> I've been saying for decades that benchmarks are almost always meaningless

I find this statement egregious: benchmarks are probably the most important thing in producing quality software and are often (outside of FAANG) the first thing to be ignored. I have the displeasure of working with extremely poor software for the majority of my career, where a simple benchmark and brain-power would illuminate the issues days-weeks-months before production issues occurred.

I also see "benchmarks are useless" used a lot by vendors who perform poorly in said benchmarks. Or use useless benchmarks (like TTFB which can easily be fudged) which is just underhanded.
> but there isn't degree you can get

In Europe you can get a bachelor of arts in product management:
https://code.berlin/en/study/product-management/
Big solar flare would do it. Probably not worth worrying about though, not much we could do about it.
There's a big difference between driving in stop-and-go traffic at rush hour and driving on a scenic road with no particular deadline. I guess some of that is "hell is other people", but I really enjoyed a national park auto tour (with audio guide) fairly recently.
Does an american city somehow have the power to impose something like this? I didn't see in the article what they actually mean. Is it a rule about workplaces, and do cities regulate workplaces in NY? Politics aside, I'm confused about what power is being used to do this?

Edit: part of what I'm wondering about is the practical terms... like are businesses registered with the city, can a city person come into a private office? What if you're a sole proprietor? What if your "employees" are subcontractors? I wasn't aware that, except for certain kinds of licenses for premises and maybe trades, that the city even had any legitimate interaction with or knowledge of businesses. Like you could be a deleware Corp renting some nondescript space somewhere eg. Just trying to picture what this actually means?
I've driven in places that use them regularly; I've never felt comfortable: Trying to change lanes and turn, while going around a curve, with traffic behind and in front of me going around curves (reducing visibility and judgment about position and speed), and also reguarly changing lanes and entering/exiting.

Are you comfortable with it? How do you do it? (Empty roundabouts are fine, of course.)
I updated to 15 awhile ago and it’s always been like that
WTF? Why?
> I can't really square the idea that the 50-150ms time-delays in question comes down to the actual programming language, but it is absolutely believable that a longer test reduces the median latency rather than a high load test for a shorter duration.

It seems plausible to me: in Fastly's case, they're using WebAssembly via wasmtime[1] which does support AOT compilation but most JavaScript code is dynamic enough that they still need a runtime JIT engine. I believe the the current approach Fastly is using is to compile Mozilla's SpiderMonkey JIT engine itself into WebAssembly and they've done some really nice work making that load as quickly as possible:

https://bytecodealliance.org/articles/making-javascript-run-...

The catch, of course, is that this still leaves a fair amount work which a JavaScript program has to deal with at runtime compared to a Rust program which the compiler can spend minutes optimizing long before deployment. This is a classic tradeoff for dynamic languages and a lot of people are satisfied with the approach of defaulting to faster developer turnaround and later converting hot spots to something like C or Rust, but I think it's definitely dodgy to use a single example of something you know to be this complex and present the results as generally representative of the entire platform.

I have no knowledge of how Cloudflare ran their tests or reason to suspect malice but not disclosing test methodology and a “no benchmarks” license clause is going to make accusations about the results inevitable. Veterans of the benchmarketing wars have stories about comparisons where someone used a configuration option which happened to disable key performance optimizations for their competitors or used examples which favored their design decisions. Since nobody can read someone's mind to tell their real intent, the best way to avoid acrimony is to have full public disclosure of the benchmarks and their methodology — and to allow other people to conduct benchmarks so they can reproduce results or fill gaps.

1. https://github.com/bytecodealliance/wasmtime
Yeah, but GP said hundreds of millions of years ago. Were there trees in the Gondwanaland Sahara?
Even better: Don't have media queries breaking at some arbitraty widths at all, and have a design, which is responsive for all widths without breaking suddenly, orienting size of boxes depending on the content.
Ask HN: Has interviewing changed or is it still a nightmare?
I'm contentedly employed full time and receive about 5 recruiter emails a week so am tempted to explore what's out there. Is it worth the time or would it just contribute further to my incipient misanthropy?
The person you replied to said “crypto” not “Bitcoin”. They can convert their coins to an algorithmic stablecoin and make the payment in a single transaction with no price change.
I completely agree with the author. I've been reading a lot about the EVM, and while there's some interesting technology involved, it feels unlikely to be able to support any worthwhile applications outside of blockchain finance or moving $ around the world[0] (since the code can really only directly reference the blockchain itself).

It's a bit like playing with a programming language in a sandbox that has (1) has no I/O functions[1], and (2) has enormous costs associated with even the most basic of computations. Ok, it's not like that; it is exactly that.

Sure, you could build a crypto toy and convince some suckers to transfer some of their wealth to you, but calling it an app platform or the next evolution of the web is definitely a stretch. I sincerely wish that wasn't the case (I'd love to find an exception), but that's what I've come to conclude.

[0] Don't get me wrong, there's tremendous value in being able to move money around the world without the blessing of governments and central banks!

[1] Any interaction with entities outside the blockchain require oracles, and at that point, you might as well throw away the other benefits of being on a blockchain.
It's a very safe assumption.

We can look at excess deaths (https://www.cdc.gov/nchs/nvss/vsrr/covid19/excess_deaths.htm) and the speed and locations it spread around the world and be fairly certain that if the virus were here in significant quantities in 2019 we'd have seen signs of it.
The post says that Easter egg only works if 'expose_php' is set in php.ini, which will also report the PHP version in the X-Powered-By header of every response. So it doesn't seem to leak any information that wouldn't already be available.
> A political action committee supporting Parson, Uniting Missouri, used the episode to attack the Post-Dispatch, posting a video on Oct. 20, less than a week after the governor’s press conference. The video accused the paper of “playing politics

Hmmmm. There’s something weird going on with the GOP. Again it has to be asked, was the changed response an attempt to scare those who report on Cambridge analytics type data slurping? And if so what on earth are the GOP and their democracy haters up to?
Location: Chicago
Remote: OK
Willing to relocate: No
Technologies: SaaS, eCommerce, react, node, many others.
Résumé/CV: https://jameswilson.name
Email: james@jameswilson.name

I have over 20 years of experience on many different levels of the tech stack, including extensive management experience.

I've led teams for Citibank, Wall Street Journal, Hawaiian Airlines.

I've worked with many emerging technologies such as VR, AI, self-driving cars, 3d talking avatars, AI-powered, easy-to-use breast cancer detection software, I have even created a project for the President of The United States.

I am looking for a role or freelancing with responsibilities similar to R&D or Integrations, Technical Product Manager, Technical Project Manager, VP/Director of Technology, Scrum Master, Solution Architect, etc.

https://jameswilson.name

james@jameswilson.name
This is def a new feature…
Population size and living standards are lagging indicators for sustainability. As it is though things are not just fine right now in the sense that conditions are such that that the unstoppable change they induce will soon be so bad that not even the willfully ignorant can deny things.
Ten Gig Is Here
speed limits... doesn't work.

I live in a city where they lowered the speed limits heavily, the result is law abiding drivers constantly almost crashing because they have eyes glued on the speedometer to keep themselves under the speed limit while on roads that "feel" faster.

And the non-law abiding drivers that will happily crash into the rear of law abiding ones, since everyone is same speed, when someone DO obey the speed limit, that person gets rear ended as the other drivers get surprised.

Instead you need better road design. (also, putting speed bumps after long wide straights is just a retarded idea, saw a bunch of times people going airborne on those, including one time where a guy managed to leave his wheel STUCK INSIDE a wall, at the exact height a person head should be...).
There's a lot of things this misses. It also completely misses the point on stuff like CP.

I know CP is bad and I have no interest in seeing it. However, I do also know that there is a group of people out there that do want to see it. Is the "anti-censorship" approach to just "shine a light on it" and let those people watch CP that's on the immutable data store?

This whole post doesn't just assume that people are by default good, it assumes that there are no bad people. That's the only scenario in which the proposed "solution" would work. Personally, that's not a bet I'm willing to make, or even entertain.
> That sword cuts both ways.

Indeed it does. And as I very openly stated, there's a time and place to discuss what you've raised as well! Even on this very post.

> I'm not trying to control.

Numerous times, you admonished me and the other poster for not bringing value to the conversation because it didn't include points that you personally find most important. You effectively communicated "If you don't include what I personally deem to be most relevant and illuminating, you should check yourself".

If that's not trying to control, I don't know what is.

> If you find yourself in a conversation you're not having, one option is to leave.

Another comment that cuts both ways. I should remind you that you joined the conversation you weren't having, only to tell someone else how they should change what they were discussing.

> in a markedly uninteresting and unilluminating direction

Perhaps to you. Again, you seem to only consider the conversation relative to your own point of view, and that continues even in this conclusion.

I do intend to leave this thread, because it’s devolved into something that doesn’t really align with the spirit of HN.
That's one way to look at it. Another is that you are driving a potential weapon and a dangerous machine. It should be treated as such. Maybe the price doesn't have to be high but unless you know of another way of making people think twice about loosing their license than money I see no other way than a high price. Besides, it isn't that expensive. Nowhere near being a luxury. It's only expensive when compared to the US system where you in most states are only paying for a piece of plastic, not tens of hours of people's time training you properly. Most European countries have the same system as Germany and the amount of traffic deaths and injured says it all. It's simply a better system even if not perfect.
I have no idea who would accept crypto as payment given the gigantic price swings.
SoftBank Strikes Again – Better.com or WeWork Version 2.0
I know that's the theory, but I don't see that happening in practice. See, e.g., TiVo, Android, NVIDIA drivers...
T-cell proliferation is usually assessed by measuring incorporation of a radioactive tracer ([3H]thymidine), which gives the total amount of DNA synthesized in a bulk culture but provides no information on the actual frequency of specific T cells. A fluorescent dye such as bromodeoxyuridine, which intercalates into replicating chromosomes, has been widely used but is not very sensitive because of the basal T-cell proliferation. In addition, it is not possible to purify the specific live cells for further characterization.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC95974/

The study you linked also showed vastly increased neutralizing antibodies, which is in conflict with what was posted here. You said that was fine because of T-cell proliferation, but that doesn't explain why the clinical trials produced a different result.
From someone outside the DeFi/blockchain space, so far mostly what I see are reports of $millions in $TOKEN being "stolen". Would love to see reports of real-world useful, in-production apps that a) require $TOKE, b) are done without increasing climate change, and c) aren't mainly used to prove the greater fool theory (once again), e.g., Bored Ape NFTs.
Oh absolutely, benchmarks are great for measuring your own performance and improving it.

I meant they aren't great for comparing two very different technologies. I've looked at a lot of serialization benchmarks, having once maintained Protocol Buffers and later Cap'n Proto, and it's amazing how wildly different the results are depending on the shape of the data you're serializing.
and yet https://www.warpnews.org/human-progress/nasa-the-earth-is-gr...
It depends on what terms you are getting but it is important to be clear that this is a bet on the Fed not raising rates, and I would argue that you should own linkers if you want to do this bet instead.

Everything makes perfect sense when the risk-free rate is -5%. If the Fed does hike late and the risk-free rate has to move to 5% then your debt will start looking like a noose.
I've lived in multiple states including California, and this is the first I've heard of red right turn arrows meaning no right on red. Good to know.

I believe I've also seen red right turn arrows in Pennsylvania, but they don't have any special meaning there. But I couldn't say for sure.
> 40 miles away from a major city is hardly the "middle of nowhere." That's still within spontaneous day-trip range.

I call "40 miles away" a daily commute distance.
tell us something we didnt already know. you can solve the speed problem by using solana or literally any of the other 100 coins that claim to be fast, or eth2 in six months

i am not even a person who is a fan of blockchains (since they are mostly poorly designed, unfounded, etc)
Much of the repair problems has to do with how small they are and the components are tiny and must be assembled so carefully that humans with fingers are just not at the right scale.
Greenhouses have a human to open the windows when they get too hot in the peak of summer.
sure, but having the ability to have an open 1GHz Athlon XP (with increases in IPC allowed by modern architectures) would be nothing to sneeze at. See https://en.wikipedia.org/wiki/130_nm_process
I'm too young to really say, but I think the widespread use of code review and project management software has caused this.
The reason why these are mostly believed to be false positive is that all current covid-19 lineages (sequences) can be traced back to a single clone that (based on mutation rate estimates) appeared somewhere in late 2019. There may have been other lineages before that, but we seem to have no RNA sequence of those lineages, so we cannot put them in relation to any existing strain. One has to wonder, where are those 'alternative' lineages now, if they existed in the first place? Sure, they may have gone extinct in the great lockdown. But then one has to ask why did those went extinct while so many other virusses didn't. An a simple (occams razor) explaination is: they never existed.
If the downpayment was accepting bitcoin then it would be a set amount like 0.1btc and not a dollar value.
While running exit nodes definitely seems undesirable due to the volume of abusive traffic that is likely to go through the exit node, I bet other kinds of relays would be a lot less cumbersome. Obviously a very well-funded attacker will always have the upper hand, and obviously, if you were to always use your own node as the guard node, it would lose some of the properties of Tor, but I bet it wouldn't hurt for more of us to run nodes. I am interested.