skysight-inc/HackerNews huggingface dataset:
I'd be curious to know where this research was performed.

They expected 'co-incubation' might produce a variant that escapes prior immunity, as represented by convalescent plasma containing antibodies. They performed this co-incubation for "more than 90 days". They confirmed what they were looking for – what they were essentially trying to create: a virus with a novel collection of mutations that escaped immunity.

It was thus plausibly gain-of-function research, aka "Enhanced Potential Pandemic Pathogen research", on a virus whose danger level was far beyond "Potential Pandemic Pathogen". This research enhanced an actual pandemic pathogen.

Did it pass gain-of-function review? How secure was the lab it occurred in?

Note that some theorize the Omicron variant, now causing panic & fresh travel bans around the world, originated from a long-lived infection in an immunocompromised patient – where it had time, like in this experiment, to incrementally add many mutations over many generations. Omicron was perhaps even under the selective pressure of a similar external-antibodies treatment.
This is quite interesting. Are you able to share any more info about your journey?
> That's a very shortsighted comment.

Is it though? GP claims to have been using terraform for years.

I have been using terraform for some time too, and from what i've seen well written providers will error out in a safe and controlled manner instead of making the whole thing crash.

> Even in "mature" ones as aws/gcp.

Can't comment for the gcp provider, but I've worked at companies where the terraform provider is used quite extensively and really can't recall a real crash that created serious problems. And i've been also using the openstack provider, again, quite extensively, with not much troubles.

So in conclusion I think that it's your argument that's really short-sighted, because it's based on FUD and situations that are theoretically possible but sufficiently remote in the real world that they can be ignored.
scroll down and it should pop from the left at some point. Maybe try in private mode?
There's plenty of autism in my family, I've read plenty on it, have plenty of personal experience, and plenty of empathy for autistic people. That said, most of this list hits home, and not just in a surface-way.
Please do not Troll here.

You have made similar comments in the past and have admitted to trolling.

Quoting your own posts: https://news.ycombinator.com/item?id=29162093
TL;DR If it got to lungs, they (COVID-19, flu) are both worse.

Any lung infection will have a lasting effect (in survivors).

In lucky cases, pneumonia is caused by bacteria sensitive to antibiotics. If it's viral (flu, SARS/MERS/SARS-Cov-2 or anything else) or antibiotic resistant hospital bactery, that's basically it.
Get an MRI and consider that psychological stress can have physiological or physiological-seeming consequences.
Depends on which card you have used and which scheme was used to process;

In general, "double scheme cards" (MC + Maestro on one card) should offer you the option to choose, while at the POS, which scheme should be used; the thing is, the merchant is not required to offer you this question, and there is a "default scheme" on such cards.
This means, in cases the merchant does not ask you, the default scheme is chosen, which is usually the one that brings in more fees for the bank/PSP.

And: Depending on the contract between you and your bank, it maybe that you couldn't revoke the "lastschrift", yes.
But because they try the rest of us suffer the consequences of more expensive and slower hardware and all kinds of other problems.
The added transmission, overall prevalence, and longer and more severe resulting sicknesses make mutation more likely in un-vaccinated populations by several order of magnitude.
Corded Wahl professional hair clippers. It’s the AK-47 of hair styling products: indestructible, never jams, and incredibly low maintenance. Clean out the detritus and give it a little oil now and then and it will work practically forever.
S-Expressions, the sin is right there in the name.
Somehow right clicking + saving worked fine on Safari (desktop). I tried it a couple of times and it worked in all cases; sometimes it took a second, sometimes more. Perhaps the server dropped the connection?
The semicolon is dead; long live the semicolon.

I'm particularly bored tonight.
Actually, in the first case, its not instantly take, instead it is marked as a "abgesicherte laschrift", which is equivalent to enter card+PIN, meaning you can't revoke those.
Though, sure you can, but it will end up with nice discussions with your bank :)
It can't be accidental that the article has multiple paragraphs where they use an em dash where a semicolon would've also been appropriate.
"I like an escalator because an escalator can never break, it can only become stairs. There would never be an escalator temporarily out of order sign, only an escalator temporarily stairs. Sorry for the convenience." - Mitch Hedberg
Yeah, I found it quite sweet. I usually hate Intercom-style 'conversational' popups, but props to the author - he's made it unique and endearing enough that I would definitely have signed up if I were a front-end dev.
Yes, "many of us" never knew about the risk of Influenza. That doesn't mean it wasn't there. COVID is significantly less dangerous to the younger age groups than Influenza[1]. We've known this for a while now, but you rarely see a table comparing the two, because the dogma that "COVID is not like the Flu!" must not be questioned.

At the same time, COVID is also significantly more dangerous than Influenza for the older age groups. The two diseases are very different, but we still need to compare them to get an understanding of the actual dangers. We've always lived with the danger of communicable diseases. It's never going away. If we constantly bombard people with the risks of this particular disease, it will cause a lot of stress and anxiety, which is significantly associated with all-cause mortality.

[1] https://freopp.org/comparing-the-risk-of-death-from-covid-19...
my understanding is that the machinery underlying it are a bit more complex than what terraform would do.

if anything that would be because the kubernetes operators implementing the Cluster API for your specific cloud provider would be implemented in a continuously running control loop, thus picking up changes... whereas with terraform you would have to run terraform from time to time.

edit: plus of course all the other features coming from kuernetes like mutating admission, validation, rbac (eg: only allow some people to create clusters or allow people to create clusters without granting access to the underlying cloud provider) etc etc...
Because you should be skeptical about their claims about being backed by real money.
Twitter has rescued the semicolon for me as a way to save a character since an em-dash requires an extra space.
I do not mean any offense to you personally with this comment.

I think science should be limited to scientists, and this is a good example. I am not a researcher but I know enough to know what I do not know. People saying that this "virus mutates quickly" is not only wrong but makes it scarier than it is.

Every virus mutates when it is in a new host. A variant is created when that mutation confers some survival benefit.

But COVID actually mutates MUCH SLOWER than influenza!!!!

https://pubmed.ncbi.nlm.nih.gov/33064680/

"Both viruses depend on a viral RNA polymerase to express their proteins, but only SARS-CoV-2 has a proofreading mechanism, which results in a low mutation rate compared to influenza."

https://www.astrazeneca.com/what-science-can-do/topics/disea...

"The average mutation rate of SARS-CoV-2 remains low and steady, and is much slower than other RNA viruses such as influenza viruses. Unlike coronaviruses, influenza viruses (which cause the flu) are prone to changes through processes called antigenic drift and antigenic shift.3,4"

The only thing that makes SARS2 a bigger problem that the flu is the R value, or how fast it spreads. Flu is between R1 and R2, while Delta was between R5 and R7.

So the issue is not one of mutations, but of spread. Vaccines do not stop the spread and that is a problem. Even when vaccinates you have no symptoms but you will catch the virus and create mutations.

A total worldwide lockdown, IMO, would have stopped this dead because of the low mutation rate. But unfortunately governments favored the economy over lives. And I also blame Fauci and Trump for not making enough N95 masks and Fauci actually discouraging their use in the beginning.

At this point it is with us forever since wildlife will continue to spread it. Eventually it will settle to a place where it kills X amount of people and we will be OK with it as we have become OK with the flu killing 30,000 to 70,000 people a year.
Calling the iSeries (AS/400) legacy is a bit disingenuous. It is a currently developing system with features that aren't duplicated in the mainstream. At this point, I honestly crave a Unix/Windows alternative to gain some popularity to break the tunnel vision of the industry.
> Zero based indexing makes zero sense

The sensibility of the index choice is equal to the starting value of the index.
So is society. When you’re a kid, it seems like everything is incredibly well organized and orchestrated.

As an adult, you realize the world is a patchwork of semi-functioning systems and it’s a miracle the whole thing works as well as it does.
> will the public think twice about Boeing's competence when booking flights

No. Make it $5 cheaper and the public will buy it. (That’s how “unbundling” became so effective and why you get nickel and dimed by a lot of carriers now: so they can compete on headline price on online travel aggregators.)

> or airlines when purchasing planes.

Unless the previous is “definitely yes!”, this one is also no.
This story stinks, first red flag that the author might not be sane:

> Sandy Funk, had begun having blackouts at the age of 37, having developed a brain tumor. She got herself onto a diet of natural juices and vitamins, and was able to live for another 18 years, [...]

Ok the [...] is this:
> but only after they had removed two thirds of her tumor via a surgery.

so it might be bad writing, but it could be read like the unnamed author could be trying to claim juices and vitamins help against brain tumors.

After that, I took the anti-government and anti-EPA missives with a grain of salt, if I cared more I would've done the research to see if they're writing the truth or are just spreading another "government is bad" conspiracy theory.
This article does not demonstrate understanding of the semicolon; it is used incorrectly in the first sentence, for crying out loud.
SEPA has 4 message types, currently:

- PUSH:
- SCT Standard
- SCT Instant

- PULL:
- SDD Core
- SDD B2B

As a bank, you are not forced to support all of them; also, it depends on the local consumer behaviour: in some countries, pull mechanisms are not that widely accepted

DISCLAIMER:
Lead Payment Engineer at an European Challenger Bank, i'm implementing that stuff in the backend, i'm mainly talking to our central bank.
interested in hearing which addons are required to get basic functionality ?
I'm pretty sure it only discards the original after x number of other (new) images have been decoded. (Or perhaps it's memory footprint based?)

I ran into a Chrome performance bug years ago with animations, because the animation had more frames than the decoded cache size. Everything ground to a halt on the machine when it happened. Meanwhile older unoptimized browsers ran it just fine.
Lego is pretty high on my list: it's all about composition with reuseable components that have just the right size. Also, the basic interface is stable since 1958.
If two people want to travel from the suburbs to the city and they have their own cars, two journeys are made.

If they travel by taxi there's only one car on the road - but the taxi has to do a third trip, going back from the city to the suburbs between passengers. That trip is likely to be made without a passenger - because in the morning rush hour, far more people want to go in one direction than the other.

Of course, in some cases taxis may help reduce congestion - transporting people to and from train stations, and allowing people who usually cycle to transport bulky items, might enable more car-free living.
94% of Searches Happen on a Google Property
As an autistic person myself, but by no means an expert, I can say a few things. Adding here because there are at least two replies to parent that are the same "well, it seems like a useful list" at time of reply composition.

First: Asperger's syndrome is not actually a recognized diagnosis anymore. It's all just autism and autism spectrum disorder. That's in part because we've recognized that it is all part of the same spectrum, and probably at least in part because Asperger was a Nazi. More about both points here: https://www.nature.com/articles/d41586-018-05112-1

Second, while some of the notes in the gist align with my own personal, lived experience, the vibe of lacking empathy absolutely does not. The Leader article cited in the parent comment aligns better with my own experience at least.

Third, that list is absolutely just a random box of facile observations. Note a particular thing about one particular autistic person, and try to coerce it into aligning with a mental model that you think must be true of all autistic people, with no particular actual supporting evidence.

If you're interested in what it is like to be autistic in an informal way, I recommend trying to get your hands on a copy of "Sensory: Life on the Spectrum" https://www.kickstarter.com/projects/schnumn/sensory-life-on... as it is a good, crowd sourced book about all the different ways autism works. If you want a deeper, more scientific analysis of autism, there's plenty of peer reviewed literature out there. But the linked gist in OP is neither (a) peer reviewed literature nor (b) reflective of autistic experience in general at least.

Finally, while some folks self-identity as "aspie", I would find it _extremely_ offensive if anyone used that word to refer to me or anyone else without express permission. Just say "autistic person".
Lnx does fuzzy searching over 5x faster with SymSpell
Sadly, you can't setup find my.. for them if you don't have an iPhone, which seems blatantly anticompetitive behavior from Apple.
Optimising Memset and Memcpy
> Vaccines included, some of us were never told that "a flu" could frequently provide long term impairment

The article you link does not claim that long term impairment is frequent. From the article:

> A UK study estimates that between 7% and 18% of people who had COVID-19 went on to develop some symptoms of long COVID that lingered for at least 5 weeks.

However, this study does not consider severity of symptoms. Someone with a persistent cough for 5 weeks after infection is considered to have “long COVID,” just as someone with massive loss of pulmonary function is considered to have “long COVID.” It also does not control for long COVID symptoms that are merely correlatory, e.g. insomnia. I had intermittent insomnia for the first few months of the pandemic, because I was afraid for the state of the world. Yet if I had contracted COVID in those months, I too could be considered a long COVID sufferer.

I have yet to see a study that estimates the prevalence of severe long-term symptoms causally stemming from COVID infections. My guess is that it’s vanishingly small; given the sheer number of COVID infections, it would be obvious to everyone if a sizable portion of them actually went on to develop severe long-term symptoms. If 7-18% of COVID infections actually resulted in the severe long COVID symptoms described in the article (e.g. “extreme fatigue, breathlessness, [or] difficulty concentrating”), it would be extremely evident on a societal level.
Briefness does not (and cannot) go against proper structuring - structure exists regardless of brevity. Comma, semicolon, period, new paragraph: the expressed thought has a structure and its sets of relative closeness are indicated through them.
Omicron Variant – New Covid Variant Worse Than Delta? (Doctor Mike Hansen)
Here in the Netherlands along with the cradle-to-cradle hype a paper reality has been created where all kinds of hazardous waste can be turned into 'building material' and then used (read: dumped) anywhere freely, and making double profits. There was a TV series last year, "De Vuilnisman" (the garbage man) that addressed various ways this happens.
perhaps you shouldn't take it offensively. Sufficient vision is simply the norm, that's what normal means.
o A large part of the mechanism by which ncov kills is the immune system's response. There's no "kill the host" gene that you can simply snip out. It does harm as a second order effect, not as a feature.

o DNA is really complex to work with; designing proteins is harder when you don't have the luxury of being Nature itself and trying it out in vivo.

o You will have a PR problem of hilarious proportions. Virus genetic engineering research labs are a few points short of popular support at the moment.
I agree. dang, if you see this, what do you think?
SARS2 mutates much more slowly than influenza so the evolutionary path to lower risk will take much longer.

This make me feel that spreading it is better than not spreading it at this point. Luckily it is much more infectious.
Meh. Grammar, in general, is on a steep suckiness trend.

For example, when was the last time you saw someone on the web actually use the correct past tense of "lead (verb, transitive)"?
Interesting!

So, TIPS is just one of the available clearing mechanisms available for the SEPA Inst scheme. (The other one is RT1, which is live a little bit longer)

Currently, there is no "regulatory forced" interoperability between RT1 and TIPS, though the 4CB are discussing it. (Esp. since RT1 is a private clearing mechanism, while TIPS is the one operated by the 4CB)

And, regarding fee: You are wrong - depending on the local jurisdiction (esp. consumer rights), a bank may for sure charge for processing SEPA SCT Instant messages. Over here, SEPA Instant transactions are around 0,50EUR - 1,00EUR, currently; some are also offering them for free.

DISCLAIMER:
Lead Payment Engineer at an European Challenger Bank, i'm implementing that stuff in the backend, i'm mainly talking to our central bank.
Yes it was. Thankfully there are people smarter than these "researchers" who just simply asked the guy what he'd meant.
As far as I understand the article instead of getting 1/4 the stocks each year for 4 years they get it all at once, hence after 1 year you get 100% of the stock instead of 4. Is that not what was meant?
> "technology is neutral, it's how you use it" line.

Seems like such an obviously true statement to me, that the only thing to add is that you cannot un-invent, abolish or wish it away. Folks who believe in the "complete nuclear disarmament" fairy tale have a hard time with this.
And with 2.0 banks like Monzo, the account holder gets notified of the Direct Debit setup, how much is likely to be debited, and can easily cancel it from the app. That reduces the risk of fraud quite a lot.

In exchange, it saves a lot of time both for the customer and utility provider as the risks of mistakes are reduced considerably. Invoices get paid on time.
Without the cartel it would be a bunch of random producers selling in a competitive market. Now it’s a single seller of Quebec Maple Syrup and you have to buy through them. It looks like some exceptions (small producers).

https://en.m.wikipedia.org/wiki/Federation_of_Quebec_Maple_S...
True, that works as well.

Either way as a tenant it's best to do manual payments (even if they're automated on your end) each month so that lowering rent, if necessary, is straightforward.
The phone number has been in the email for over 9 years:

https://www.flickr.com/groups/olympus-e500/discuss/721576308...

It's legit.
It's the Oral-B Vitality 170
Wouldn't be surprised if it's created by people who are responsible for chart colors across all of Google's tech products: Google Console, Datastudio etc. "Here, have barely distinguishable shades of blue", or "in your charts you've setup errors will be blue, and successes will be ... also blue"
As far as I can tell the one I have was made in France in the mid 1970s and is irreplaceable.
yes there are a few difficult areas like that around atl. sometimes I'll just get off an exit early or late if I think what I'm about to do is too dangerous for myself or others.
OMG, LOL... it's literally the scenario from https://www.youtube.com/watch?v=M94ii6MVilw :(.
In which country and what are you buying?

In my experience (UK) the only services accepting bank transfers are financial institutions (Coinbase, Revolut).
Most stores prefer to pay CC fees and have a smoother checkout experience, probably to grab those extra % points of customer converting.
A lot of e-commerces online even offer Paypal (even more ridiculous fees and infinite hassles for sellers) just because it's more user friendly and can help conversions a bit more.

A couple of years ago, I even opened 2 cash isa saving account for 20k each paying by credit card because that was the only option the bank accepted.
and fire. one way swing allows the frame to wrap around on one side – increasing fire resistence
What would you call it? Non-classical-sort-of-css reset.css is a bit long to be fair.
Many doctors believe what you say and dismiss patients as psychosomatic if they can't find anything obvious. Sometimes they refer them to psychiatrists or insinuate they are drug seeking. It's a disgrace. This treatment from health "professionals" almost drove me to suicide.
Actually my own research got me into a path of finding out I have a rare disease and I had to pay private consultants to help with diagnosis. Only then and a threat of lawsuit got the doctors treat me seriously and I actually got help.
I wonder if this will translate to big sales at the consumer end...
You shouldn't do that with an em-dash.
It is perfectly possible to be right for the wrong reasons. Unfortunately that can eventually catch up with you.
EU invested a billion EUR into creating a Google alternative some years ago. Naturally, nothing was ever heard from the project again. Such things happen on a regular basis. Money shortage is not the problem.

There are also many big companies, for example VW could have bought some AI startups or Uber competitors.