skysight-inc/HackerNews huggingface dataset:
It is not the usual doctor stuff, but it should be.

I was misdiagnosed my whole life even though it was obvious there was some maternal genetic (metabolic/mood/immune) issues passed down through my family. It was only my own efforts at understanding genetics and the role nutrition plays in creating and controlling oxidative stress was I able to ween myself off of medications (many of which made me worse because breaking them down caused even more oxidative stress).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841237/

The research fails at being implemented because these are polygenic disorders. ME/CFS can be caused by several different genotypes, so they will have to look at each person individually for answers.

Doctors do not care about nutrition and they do not yet understand the viability of vitamins as cures or prodrugs. I had a doctor yelling, yes yelling, at my friend saying she was not anemic and did not have a B6 deficiency. She went to another primary care doctor and she confirmed the anemia and when's he had her serum B6 tested she had a serious deficiency. The doctor put her on B6.

Since I was a child I had mood issues (Anxiety, Depression, Bipolar, Aspergers), fatigue, chronic muscle pain (lactic acid), and immune disorders (Ankylosing Spondylitis). It turned so bad I could not work anymore and have been on disability for 20 years. Yet, I getting any type of non routine test is a battle and when I do, and they are off, they just shrug. Why not look into it more so I can start working again? And it will be the same battle for people with Long Covid.

Regardless, Manganese (not magnesium) has changed my life pretty drastically. I do not think there is a final solution for me since my condition is genetic, but what I have done helped more than any medicine I have ever been on. And when I tell my doctors they say; "Well, I am glad that worked for you." They are not even interested.

Without knowing your genetics or having labs you can test with some supplements, but just know if you have a bad reaction that still tells you some good information! But a bad reaction is a signal what you are taking should be stopped.

Understand haw oxidative stress is controlled in the body and you will make great progress. For example, exercise increases oxidative stress, so, long covid...ya know?
This article was cute, but the author completely ignored one of the key aspects of online dating: appearance. I think this plays a huge role, for both men and women, and to ignore it is naive at best, and misleading at worst.
Game Design and programming are two completely different sets of abilities.

Programmers can design a game, and game designers can do some programming, of course. But in modern days, the core way that both professionals interact with engine editors is completely different.

Game Design in general is closer to art or being director than to programming.
A beginner friendly stack if you like (modern) php 8 is Laravel. You can use Laravel sail to develop using docker without having to install anything on you local machine except for docker of course. You can add in laravel breeze for basic authentication and add laravel Livewire and alpinejs to avoid having to use JavaScript. You can easily launch this stack either on laravel forge or use the digital ocean app platform to avoid high costs of Heroku or complexity of aws. There are many resources for laravel. I’d start with free YouTube videos. I have found codecourse.com a very good source of how to build a verity of decently complex laravel applications
>those whose homes could not fetch anywhere near as much via traditional sales channels

Isn't this just another way of saying the models overstated the value of the homes?
Why Web3’s Shared Data Across Applications Doesn’t Matter
The merit system that the Chicago professor suffers is really laughable and speaks more to his general critical thinking than anything. ACTUAL critical race theory explores how institutions, especially in America, do have the original sin of benefitting certain people over another. So, this whole judgement of merit and fairness has to come from somewhere. An institution. How people are evaluated isn’t straight forward, and straightforward evaluations are rife with embedded racism, sexism, classism, etc.
They've been going that way for a long time because it was the only way to keep up headcount growth after their initial growth phase pulled in all the experienced people who were already willing to move.

Even when I was there, the number of inexperienced grads who had never known anything except Google was growing rapidly. And they unfortunately seemed much more prone to bizarre outbursts, bad behavior and extremism of various kinds. They took where they worked for granted.
>what was the cost involved

For BBS system operator (sysop), he typically bought a high-end modem like US Robotics for $500 to $1000. A dedicated computer with expensive harddrives. Some paid for commercial BBS software such as PCBoard. There were monthly costs for dedicated phone landlines.

For most users, they just bought a modem and re-used their existing voice landline.

>How similar was it to current social media networks

In terms of participation, the dial-up BBS scene seems somewhat analagous to today's Mastodon instances that are run by altruistic admins who foot the costs themselves. BBSs typically had 1 or 2 phone lines which means only 1 or 2 people could be "logged in" at a time. Some BBS had discussion forums but unlike Mastodon, each bulletin board run by a homeowner was very local/regional because extra charges for long-distance phone calls was still a thing. So 99% of the regular users of a particular BBS would be in the same area code.

There were some commercial BBSs with multiple phone lines that had paid memberships. The attraction there was larger harddrives with more things to download (shareware, etc).

>How big the industry around it actually become

The BBS community was very small because it was mostly computer enthusiasts. A very niche communications platform like CB radio for truckers or ham radio. The dialup modem service that attracted more non-computer folks was AOL.
Fragmentation is such a silly argument these days when you can install Steam, Spotify, Discord and Telegram on literally every standard Unix-like system these days. The "average person" you're describing isn't going to care about their package manager, their DE or their GTK theme, and why should they? 10 years ago, people used to complain about all these things that Linux couldn't do, and how that was the real reason it died. Nowadays that argument seems to have morphed into "there are to many ways to do things!" which seems pretty shallow to me.
My takeaway from the Zillow debacle has nothing to do with OPs approach. Instead I look at it from the Antifragile framework.

It looks like this business model had a lot of ways to go wrong and very few ways to go right. In other words, it was fragile. It doesn't even sound like the Black Swan of Covid was needed to make this fail.

In other words, if a system is fragile, you can bet on it breaking sooner or later.
Not for anonymity, but it sounds like you’re describing https://pkt.cash/ otherwise. The “proof of work” is bandwidth-hard.
I like it - I am also a fan of Excaldraw.

I noticed some kind of error coming up in trying to export to pdf - other than that it seems to be working well.

I am using the following set up
```
uname -a
Linux arch-t460p 5.14.16-arch1-1 #1 SMP PREEMPT Tue, 02 Nov 2021 22:22:59 +0000 x86_64 GNU/Linux
(base)
~ via 🅒 base
firefox --version
Mozilla Firefox 94.0

```

I am not sure, but this message that pops up seems to suggest that it might not be establishing a good naming convention for the save.

```
application/vdn.excalideck+pdf (92.6 KB)
```

I will put an issue on the github project if I see it persists in the next day or two.

Thanks for sharing - great work! Between presentation tools like this and reveal-md we have some nice options for building out presentations.

Thinking about it. It would be great if it was possible to export each of the slides as independent png/svg as well. That would allow some possibilities to open up for using it with reveal-md
I find building Node CLIs to be a lot easier and less error-prone if you use `clime` or `oclif`. You can use `oclif` with raw JS, but it's kind of nasty compared to TypeScript.
Hey for a long time i was also very sceptical. However i can refer you to this paper to a really cool applciaiton. https://www.youtube.com/watch?v=kP-dXK9JEhY. They baseically use clever GPT-3 prompting to create a dataset, you then train another model on.
Besides, you can prompt these models to get (depending on the usecase) really good few shot performance.
And finally, github copilot is another pretty neat application.
Perhaps dividends? Interest on deposits and investments? I would hypothesis that if a person has ten million euros sitting in a bank somewhere, it's not just sitting like dead trees, but perhaps earning interest. Musk does not seem to have too extravagant of a lifestyle, so I presume on what evidence there is, that everything is likely owned and paid for by his companies, as expenses, etc.
The point isn't to determine who is or isn't clueless. The point is how we deal with each other's cluelessness.
Looks really good, thanks for sharing, appreciate it. The timezone requirement is a shame though :(
I can give you many counter examples, such as hepatitis C, that were previously incurable or hard to cure. For some diseases we have managed to get a sterilizing (=complete) cure, for some others (like HIV) a functional cure (=you live long and healthy even though the virus is still in your body). In part, it is a function of cost allocation.
> Prohibition of alcohol never worked, but taxing it certainly does.

Yes because clearly we've beaten alcoholism /s

> Sin taxes don't disproportionately affect poor people

Do you know what a regressive tax is? I suggest you do a quick search. Sin taxes ARE in fact regressive. Poor people spend a larger percentage of their income on these taxes, even if they consume the same quantity. Its basic math.

"There should be no debate about whether taxes on food, alcohol, tobacco and soft drinks (‘sin taxes’) are regressive. It can be easily demonstrated empirically, and countless studies have done so. As with most indirect taxes, they take a greater share of income from the poor than from the rich in all plausible scenarios."[1]

[1]: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3853609

> You also don't just up and die, generally speaking. It is instead lung cancer, heart disease, disability, and overall failure of health over time. The effects by that point are not readily reversible.

Why are you ignoring the cost of living longer? Smokers still live long enough to work into retirement, on average.

"Ultimately, the thin and healthy group cost the most, about $417,000, from age 20 on. The cost of care for obese people was $371,000, and for smokers, about $326,000...

"This throws a bucket of cold water onto the idea that obesity is going to cost trillions of dollars," said Patrick Basham, a professor of health politics at Johns Hopkins University who was unconnected to the study. He said that government projections about obesity costs are frequently based on guesswork, political agendas and changing science."

[2]: https://www.nytimes.com/2008/02/05/health/05iht-obese.1.9748...
2. esbuild has support for TS (it strips the type annotations out during build), and is plenty fast (compared to webpack, rollup etc). So bundling itself should never be an issue. The other aspect is type checking. If you want TS to type check your project, then yes it takes a bit of time. But that's no different than running tests. Of course running those will take some time. Once the project is bundled, the startup time should not be affected at all, it's all JS anyways.
It's a great forum, but it's wayyyy more technical than HN. Anyone just trying to keep up with what's being built will get lost in casual zero knowledge math very quickly.
A nerdy girl fighting with her much more socially-adept little brother over use of the phone line their parents gave them for Christmas, typing AT commands into XModem on the TRS-80 her uncle gave her after he moved on to PCs, using a 300 baud modem that did plug into the telephone line (not an acoustic), but required listening to the carrier tone and hitting the red Connect button at just the right moment… to play Legend Of the Red Dragon and download the Anarchists’ Cookbook and see if someone responded to a message you posted on FIDONet a few days ago
This is a return to feudalism
How many % of the time does it produce code that compiles?
GPT-3 is fairly effective at summarization, so that's one potential business use case:

https://sdtimes.com/monitor/using-gpt-3-for-root-cause-incid...
In what way is the industry designed that way now? Maybe some get sucked into management roles, but I don’t see any evidence of a broad design to push them out.
> People aren't going to pay 8 dollars for a big mac

They will. Grocery prices are getting out of hand. I live in a particularly expensive part of Canada, but a single steak is $25 at the grocery store. A pound of ground beef is around $10-15. A single beet is like $2-3. A pound of potatoes is $5. 12 eggs is $8.

I'm spending $30-40 to cook dinner for two typically. Restaurants seem like pretty decent value right now.
Terrible terrible reporting. Instead of laying out the facts about the situation, the reporter quickly jumped on the conclusion of blaming the “rich”. There is no objective reporting, no objective diagnosis, no alternative perspectives, just a singular narrative.

I figure an average citizen can do better reporting than nowadays journalism school graduates.
Idunno the real villain is that bullshit, costly "per-row" pricing
Glass is the hidden gem in a carbon-neutral future
> This is one of those 'worse is better' things in language design, I believe. It guarantees simplicity, traded off against extra verbosity.

And with top-level await the restriction goes away (albeit the ESM equivalent is still a bit more verbose).

(await import('anything'))(...yup)
Ask HN: Starting a career as a programmer in my mid-40s
I'm fascinated by what I read in HN everyday. I want to start my career in IT. I'm now 44 though, and trained as a mechanical engineer in my career and spent the last 20 years in business (finance, strategy and operations).

I'm looking for wisdom and pointers from the community here.

How can I go about it? I have access to Coursera/EdX and around 1.5 years to focus full-time on retraining. Any advice would be appreciated.
https://replika.ai/
If you intend to work with anything front end or node related the 100% yes. I was skeptical at first, but would say I am fully converted.

The tipping point for me was when I tried to implement an order book (finance data structure) in typescript, and got it running pretty much on the first run. In the past, I would always screw up one of the structures, such as forgetting to pass an argument, or a field, or something similar.

The type system is powerful, but gives you escape hatches such as "any" which is useful when you run up against eg. interacting with the DOM where these things can get quite annoying.
People were blaming cryptocurrencies miners for the prices of GPUs, when in fact it was the AI researchers who bought all the GPUs. :D

I wonder what if somebody designs an electronic currency rewarded as payment for general GPU computations instead of just computing hashes? You pay some $, to train your model and the miner gets some coins.

Every one is happy, electricity is not wasted and the GPUs gets used for a reasonable purpose.
I hope that one day it will allow me to write down my thoughts in bullet-list form, and it will then produce beautiful prose from it.

Of course this will be another blow for journalists, who rely on this skill for their income.
I saw it as a really fantastic riff on David Brin’s “uplift” series. In fact, Tchaikovsky calls this out explicitly in naming one of the (IIRC) habitat orbiters Brin.
"the Zillow failure was largely in part due to humans 'overriding' ML outputs in order to meet their quotas"

https://twitter.com/sh_reya/status/1457094567111528455
I found a bunch of churches were built on ground that has been shown to contain soil bacteria with anti-biofilm properties. This means the 'holy ground' was literally able to heal wounds. Likewise, a lot of 'holy water' has similar healing properties because it often contained gold and silver nanoparticles.

The ritual use of these sites usually occurred afterwards once economic situation and custom solidified it as an area of rulership. Often cargo-cult'ing what would have been a genuine healing process.
it's the exact same link and title. De-dupe does work, it's probably just a 'after x days allow' thing. Shrug.
As a teenager, I got so into BBSes at one point that I started calling the long-distance ones just to see what was out there. I didn’t know what I was doing to some degree. One month I ended up generating a bill of something like $300—not exactly a fun thing to explain to a parent.

Soon after that happened, we signed up for a traditional ISP with unlimited hours.
You can prompt GPT-3 in ways that make it perform various tasks such as text classification, information extraction, etc... Basically you can force that "meaningless prose" into answers to your questions.

You can use this instead of having to train a custom model for every specific task.
Seems like a pretty innocent, tongue-in-cheek comment?
While the generation is fun and even suitable for some use cases, I'm particularly interested in its ability to take in language and use it for downstream tasks.

A good example is DALL-E[0]. Now, what's interesting to me is the emerging idea of "prompt engineering" where once you spend long enough with a model, you're able to ask it for some pretty specific results.

This gives us a foothold in creating interfaces whereby you can query things using natural language. It's not going to replace things like SQL tomorrow (or maybe ever?) but it certainly is promising.

[0] https://openai.com/blog/dall-e/
NATO alphabet, phone numbers of close friends/family (in case my phone is lost/damaged and I need to call one of them), conversions between Fahrenheit and Celsius for common temperatures used in biology (both for science communication and also because one time an old freezer had a Fahrenheit scale and I didn't know if -4F was dangerously warm for the reagents stored inside), the 12 times tables (I never learned them as a child due to being transferred at just the wrong time, so it's never been automatic), Vimium shortcuts (disabled now since I know them by heart, but it was a good way to remind myself of features that I wasn't using often at first), Chinese characters.
The article is almost biographical, narrative and romantic, as a writing style, when it comes to the lab head. And is also very explicit about the research being a team effort - condition which makes both 'A scientist' and '"This" scientist' improper.
The author used a nice trick at the beginning of each section: phrasing the main idea of the section as a question and then answering that question.
Knowing only what we can guess about the actual problem, i’d say indexing ip ought be enough to make everything super fast.
From my anecdotal experience, the vast majority of the time (90+%).
Windows Phones of the Lumia series had historically less RAM than equally priced Android models and the performance with .NET Native was much better.

I used all my models until their hardware died.
TypeScript and JavaScript are the same language, and JS is definitely not going anywhere.
Similar in German - “verkackt”
Yes and no. Buffer and Hootsuite are 2 players in this game, both allowing to publish or schedule posts based on updates to an RSS feed you configure. Most blogging engines (WordPress, Jekyll, Hugo) come with RSS feed publishing by default.

The tricky part here is the quality of the posts will be bad. Each social network has its own social mores and taboos. Some examples:

Fediverse you refer to Twitter as "birdsite". Anything automated here, unless explicitly called out as a bot account, tends to get ignored as low quality.

Facebook does posts in long-form.

Twitter can thread it to be long-form, but each tweet needs to stand on its own with contributing to the overall narrative. Basic pagination type of splitting sticks out.

LinkedIn... I don't know anyone who posts there that isn't trying to artificially puff themselves up in corporate culture, promote their product/service, or some combination. I'm truly unsure what a "quality" post on there looks like, so go wild.

Basically, posting "<post-title> (<link>)" is probably the most ubiquitous, low effort ways of cross-posting your content but... it's pretty universally understood that it's low quality content and not likely to accomplish the originally intended syndication.
Automatic generation of positive fake customer reviews on Amazon, landing pages about topics that redirect to attack and ad sites, fake "journalism" with auto-generated articles mixed with genuine press releases and viral marketing content, generating fake user profiles and automated karma farming on social media sites, etc. etc.
> overexcited executives failed to heed the caveats of the nerd

Yes, the nerds are so well-known to consider the risks of what they create. If only they’d thought of the risk that someone could use their work in the real world, even though it came with specific instructions not to do that. Maybe they wouldn’t create possibly-destructive ML models then.

Alas, it remains a mystery what a private company might do after paying a lot of money for something. Now where was I? Ah, right! Predicting criminality from baby photos! I love how DARPA sponsors basic research with absolutely no expectation of ever using it. Although I‘d better name it README.MD, just to make sure they do not forget to read it.
Scared Shitless
The metaverse promised by sci-fi is one where each user sees a customised version of the virtual world. In VR chat for example there are options to alter the way the avatars of other user look to disable animations or ignore promiscuous trolls.

If this is the kind of virtual worlds we get we should have ad blockers. I hope that if the client is too rigid in what kind of customisation it allows it won't really be successful.
Right but the point the grandparent I was adding to, and also what I understand delecti is saying is roughly: Meta or a similar platform is an "entity who has sovereignty". For users to have a coherent experience in the platform, it may essentially be required that the platform exercises some decision-making power on what NFTs to respect and which not to. Do I get to bring in and use item X just because I say I own it, or not? Once the platform is exercising a choice on how/when to recognize ownership or not, the ownership system is no longer "trustless" and why should we bother with the complexity?
Nine Infinite Games to Play with Your Career
The first thing that comes to mind to me is WPEngine or other high-quality hosted Wordpress solution. You can install a plugin (from the web console, it's very easy) to post to social media, and there's another plugin to cross-post to Medium if that's your bag.

EDIT: I was wrong about Medium. They sunset that a couple years ago. You can use their import tool explicitly, or manually copy your post in and set a canonical link to your blog. That sucks.
> Presenting it as a social movement

Wasn't Windows 95 a social movement?

Maybe there wasn't a sense of rage from the masses towards the few people who could use a computer (via a Command line interface) but the end result is the same as the aims of cryptocurrency movement.

Moving from a world where a very few % of the population is able to use a particular tool towards a world where everybody can do it.

Reverse repos, loans off appreciating assets and so forth are only availible to few.
What's the age of a HN reader?