skysight-inc/HackerNews huggingface dataset:
It does imply that the vaccine would also inhibit DNA damage repair.

I think the key question is timescale. I suspect this would be a short-term side effect, with no real impact. If not -- if it's longitudinal -- it could be scary. I can't imagine how that would happen, though.

Virus would have the same effect, so this isn't an anti-vax argument.
Seconding this - have used VRChat a lot during the pandemic. Asking me why I’d spend time on the metaverse is like asking why I’d go to a bar. I won’t defend it as the best possible use of my time, but it’s fun to go meet people.
more tasty food available for less money and less effort over time. harder to resist because it tastes better and is easier to obtain and prepare in terms of time
and money.
For developers maybe but not for users :) And these are the ones you're developing for.

And look at other systems accomplishing this very well. Like KDE which has a ton of options and they don't suffer this problem.
The Only Bash Scripting Cheat Sheet That You Will Ever Need
He has people from all angles, but most of them are right wingers. He brings on a Liberal every now and then and if they don’t hate the Democratic Party he hardly lets them talk and uses the typical right wing gish gallop tactic to pretend he’s owned them at the end of the podcast.

Rogan does a stellar job, lmao @ that. He does a stellar job pushing the current GOPs agenda. Because he’s able to have people like you arguing that isn’t what he’s doing.
I can see this part of Dune-esque luddite uprising
Surface soundings or a towed array are vastly more economical.
His argument is that Zillow was providing a valuable service in the renovation process. Value-add allows them to charge for it.
And yet the Fed keeps printing the easy money.

https://fred.stlouisfed.org/series/M1SL
Not to mention with a paid plan you can write to support and expect a fairly quick response. I also had some initial issues backing up with tons of files (during the trial) and support sorted me out after a couple back-and-forths over several days.

I also bet if they couldn't figure out the issue, a refund wouldn't have been out of the question.
> recent Yarvin missive argued

recent Yarvin massive arguement ?
imho the Google interview process selects for people who thrive on organizational challenges.
> it just seems overkill for 99% of the people who'll purchase them

There are many places in the world where information on your laptop even criticising the government can end up in you going missing e.g. China, Hong Kong, Saudi Arabia, Myanmar etc.
Oh boy wait till the AI revolution comes in.
Exactly: Any _individual_ change may or may not be good - but change _in general_ is good, because without it there's no chance of getting better. And any hope of improvement is infinitely better than no hope of improvement.
People jump to the racism conclusion here, but it's really just a contrast issue.

Detecting eyes, for example is simply easier with lighter skin.

Light skinned black people read just fine, and super tanned white people are harder to read. It's literally contrast (light) detection, not racism.

But because the media keeps everybody primed for racism to stave off the necessary class power rebalancing, everyone jumps to racism.
Asdf is 1000! Use it on Linux and once in WSL.
The loans were also bundled into opaque securities and the “low-risk” tranches were rated and priced for a typical rate of uncorrelated defaults, not a widespread crash.
China a Risk to Tesla’s Battery Strategy, Taiwan Sees an Opportunity
One of the problems of open source is top down imposition by distros. Perhaps software should be developed with a certain regard to the preferences of the userbase? I suspect software not liked by its users is not going to be very successful in the marketplace.

Aside: Gnome is far worse than KDE. systemd is an improvement on what was there previously, albeit not the only choice. I have enough experience with X to know how difficult it was to work with, a lot there needed to go.

However, Wayland is too minimal, we're going to have lots of unnecessary differences between Gnome-wayland, KDE-wayland, and wlroots-wayland thanks to wayland's bad focus. Speaking of this, want to look at stuff that held back Linux? Maybe have some words for people who prioritized irrelevant features over basic support for remote work.
Favoring "fake meats" for reasons of ethics, rather than health, does not preclude keeping one's health. The bogeymen of "processing" and "GMOs" do not make any definitive statement about the healthiness of those products.
On the other hand, as far as I know, there was never the concept of a "brk" in the DOS/Windows world; in DOS, by default programs got all memory (no virtual memory, all physical), and there was a set of malloc/free/realloc-ish functions for TSRs and other "advanced" techniques. DOS-based Windows memory allocation goes through DPMI which again provides similar functionality to malloc/free/realloc, as well as mmap. NT-based Windows is similar but without the DPMI.
This was in managed hosting, we'd open a ticket and get teh SSDs replaced quickly, which was good enough for us. For the most part, the failure rate was about 10% of the rate of the hard drives, and concentrated in the systems with many disks, which were setup to handle disk failures, so it wasn't a big big deal.

Although we did get a couple of bad batches on our single disk systems, almost all of those failed within 2 weeks of install and we had the rest replaced.

I also suspect firmware bugs, but it wasn't convenient to upgrade them, so who knows. I did have to upgrade some of the same disks on single disk systems with low usage; the disks would sometimes timeout for no reason and confuse some of our OSes. The upgrade procedure was more or less PXE boot the manufacturer upgrade utility and hope it worked with whatever disk controller was there (eta: 5 minutes) or let the hoster firmware upgrade script run and hope it upgraded the ssd firmware and didn't mess anything else up (eta: 40 minutes per run, probably run it twice).
Yeah, that was it. Back when I heard about it, I was writing one-offs and couldn't see the potential usefulness (much less justify spending money).
Show HN: I created a referral program for my B2B SaaS
Half-life of mRNA is fairly small, as there is no shortage of enzymes that basically just break it down for recycling. The real problem would have to stem from DNA damage that occurred in the presence of the vaccine that did not either lead to cell death, or get repaired later.
So what's the truth on the ground then on government control rn?
Eh. The beige and green just look ugly to me and the boxiness of the UI isn’t pleasing to the eyes. That’s my opinion, sure, but I’d say there’s a reason why Microsoft and Apple have went with the designs they currently have.
Yeah, for context I'm fully vaccinated and not trying to create distrust of the mRNA vaccines. Just curious because that seems like a pretty bad thing. It makes sense that this would only happen while the spike proteins are actually present in your body. Thanks for the response!
Of course there is additional security.

You can't just physically remove the SSD from the machine, place it in another and brute force the encryption.
They have not been granted the trademark yet, only applied for it. So no, they don't own it
And "Sutherland" was Ivan Sutherland, who created Sketchpad in 1963, and is credited to have pioneered the field of CAD, 3D graphics in general, immersive media and the modern GUI.
Big teams at big companies are the pits.
Find a startup with under 10 people and no technical debt. You might not bank as much cash, make sure to get a large slug of equity on the off chance the company does well and you are then set.
You don’t have to put up with this garbage. Otherwise why are you reading this on YCombinator?
Wouldn't the submarine sink if the hull was so deformed that it damaged 10 sailors?
I remember reading something about it in the gaming industry; from memory it was written by a contractor brought into 3D games on tight deadlines to unstick them. And what they did was go in, ask the employees what was wrong, the employees told him everything that was wrong and what would fix it. They'd been trying to tell anyone who would listen, for months, and he was the first person who would listen. Then he turned around and told everything that was wrong to management, who were thrilled that the contractor could come in and so quickly tell them what was wrong and how to fix it, and give him the resources to do it because the deadline was imminent. The employees could lean on the consultant to cut through bureaucracy, and the consultant (who had skills) could sort out some intricate game engine performance problems, and the whole thing moved on. He did that almost routinely moving round big game companies from project to project.

I might be misremembering, but I can't find it in the HN search history.

Like an explanation given for how companies will let key employees quit, then excitedly pay more for new hires. New employees (or contractors) are all marketing about how great they are. Existing employees are all too obviously mere mortals with plenty of flaws. Of course getting rid of the ordinary employee and getting Superman looks like a good idea.

Manager spends time listening to employees complain: losing proposition, boring, time consuming, looks like doing nothing. Manager brings in amazing consultant who helps: manager looks good, saves effort, has a claim to need a bigger team and budget in future because evidence shows they just needed some extra help.
> though, in my mind, it's not very mysterious - far larger access to far more calorically-dense but nutritionally-poor foods

This doesn’t seem so obvious to me… it seems reasonable to me that any abundance of calorically-dense food would lead to obesity. I don’t think it is obvious without study that the food being nutritionally poor is a requirement for widespread obesity.
So Cal (Riverside County), and I'd say I felt like things were starting to peak in August.

This is completely subjective of course.
If housing is a human right, then slavery is too, as you demand people’s labor to satisfy your right. You are free to go put up a mud hut (provided you own the land).
Thanks for doing all that work.

> Hummus is technically a processed food. But if it's not too high salt or filled with preservatives, it's not less healthy than eating garbanzo beans with sesame seeds, etc.

I'm not sure what the properties of hummus (or artichokes or beer) implies about the properties of Impossible burgers.
> I would challenge you to find a single article reporting on any of Trump's speeches, actions, or policies in a positive light from any of the "centrist" outlets that you posted.

And why would they, when none of his speeches, actions, or policies ever accomplished anything positive for anyone other than his hardcore rightwing base? That's not bias, it's just calling a spade a spade.
> If you lie to yourself that it's people who are trying to move up the housing ladder, remember that your flat appreciating 50% in 2 years means the house you want to move into by selling your flat also appreciates 50%, so you win nothing

I think that is a little myopic.

Older buyers that are downsizing can make an excess profit in that situation. Although perhaps if excess numbers are downsizing to the same retirement homes, then maybe the retirement home owners win instead.

Also if you have a second investment property, you are definitely winning.

Finally, as house prices go up, you do end up with more equity (perhaps way more equity because a mortgage is geared lending). More equity can make a huge difference if you have any economic shocks, or if you care about passing on your equity to your children. Let’s say you have 10% equity in a $500k home, which then appreciates to $1M. If you die, you now have 550k equity, which is 11% house deposits for 5 children, or 27% deposits for each of two children. Not a bad trick.

I think a better way to think about it is that you need to own 1 house. If you don’t own a house, then you are shorting the housing market. If you own 2 then you are long the housing market. If you are a couple with kids, then you need to consider the chance of divorce (owning 1 home each is conservative, owning 1 home together is risky), and consider how much you want to give to your kids. Due to moral hazard I can’t see how you could insure against the risk of divorce.
If the vaccine is built around the spike protein (i.e. injecting you with the protein or with mRNA strands related to it) then you're essentially not getting any real, long-lasting immunity, and in fact are making it harder on your body to heal itself both with regard to SARS-NCov-2 and in general down the road. In other words, it doesn't matter if it's an mRNA vaccine or a more traditional one so long as it uses or produces the spike protein.
I think the parent's argument is more on the lines on whose politics he considers good and whose politics he considers evil.

This is just standard 'holier than thou' talk.

Every empire, nation or country ever established had to go through wars, that's just how it is. Because the existing political powers aren't exactly going welcome new political masters with roses and jasmine.

But when it's you waging wars it's for the good, when others do it, it's always evil of course.
What I Learned from Writing Online – For Fellow Non-Writers
Nix-Darwin is great! I wish the Nix installer on macOS were (a) always multi-user and (b) came with Nix-Darwin, so it could be a more NixOS-like experience out of the box.
You can do lists or read twitter as an RSS. I simply don't use twitter much since its mostly garbage. I won't be subject to fix social media, if it is a burden to use its not going to be used. Don't miss the headache of organizing quailty for my feeds when its more work to make it enjoyable for a few minutes.
>The real problem would have to stem from DNA damage that occurred in the presence of the vaccine that did not either lead to cell death, or get repaired later.

Which is what it sounds like from the title and abstract.
Newton's Lifetime Works
Feel free to grow my meat in a lab, as long as that lab is full of living cows, chickens, turkey, deer, pigs, lambs, and fish.
"Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA..."

Can anyone translate?
What does America get right?
See https://en.wikipedia.org/wiki/Fatty_acid_ratio_in_food - it looks like canola is less bad than most other seed oils but still not ideal. I've been using avocado oil but looking at this chart I am thinking I will incorporate more butter and coconut oil.
> In a word, we could call this resignation by a thousand cuts, which makes it unexpected for managers.

Eh eh eh, this feels like reading the Phoenix Project all over again: "are you me!?"

My first job out of university was a job at a BigCo, right in the middle of a Death March. Nobody at the beginning of the project remained. Most people who "finished it" were new comers like me or "team leads"(tm).

The three years I was there my teammates and I tried to push numerous changes and much needed improvements. Every time we had push back, especially by the team leads who literally shouted everyone down; I now have a profound hate for people with loud soprano voice by I digress.

I tried my best to raise up problems, find their roots and solutions. I mean, I couldn't be subtle that I wasn't satisfied with what I have seen.

And yet when I quit, my colleagues all could point out reasons of why I quit and yet none expected that I would leave.

As the article pointed out, you should quit early and make sure your reasons are known; your old colleagues will owe you and this is pretty much the only way they can get the message.
a keto/low-carb diet is a workaround for a mechanism that's broken in a lot of people

I think you're onto something from my own experience. I don't think you are entirely correct though. It's not a workaround as much as cure.

This might just be anecdotal evidence but my body was definitely broken. My gut was b0rked and I was in a cycle of eating more and more carb-y food to not feel hungry/cravy/fatigued all the time.

What getting on the right probiotics and doing keto did for me was what I think is to restore the natural state human bodies should be in again. I finally am able to feel "full" again and eat when I'm actually hungry vs. just eating three meals a day (plus 'cravings').

Now I don't subscribe to any religion but I do think that any religion that includes a "fast" does right is to basically do something akin to keto. I don't believe in any of the religious aspects of fasting but I do recognize that the easiest way to get a large populace to stay healthy is to subscribe them to a religion and then let the religion dictate things that keep them healthy and happy.

E.g. I don't eat breakfast any longer. I just don't need it. I don't feel hungry in the morning any longer. I oftentimes don't even feel hungry at lunch any longer and only do so around maybe 2pm. Not being bound to traditional meals and customs around eating helped me with this. I just go scour the fridge at 2pm to find some cheese and eat some almonds. Maybe some peanut M&Ms (at the office - at home it'd be say raspberries with cream). I can totally recommend peanut M&Ms with cheese actually! Awesome combination!

As you can see in my comment history some people have asked before after comments like this one from me. What I did was try a lot of different probiotics but what I think helped in the end is Garden Of Life - Primal Defense. You don't have to use that brand but what I think did it is the Bacillus Subtilis included in it, which wasn't part of any of the other probiotics I tried. I'm sure there are others that have that one. I started off with 1 a day, then 2 a day, then 3 a day and I felt like crap for a few weeks. Then it all went away and I felt awesome. I'm still on those to make sure I maintain a healthy gut flora but I'm down to one in the morning and one in the evening and I also made Sauerkraut from it (i.e. empty a capsule into your Cabbage and let it ferment).
Votes typically take a few seconds to resolve, possibly longer under load. HN's JS indicates them immediately when you're on the page.

Check your profile's upvoted comments / posts link (https://news.ycombinator.com/upvoted?id=wolverine876&comment... -- that's private for you only) to see if your upvotes have been registered.

If not, drop a line to hn@ycombinator.com as I suspect they'll be interested.
Yeah a direct link would have been better: https://www.poor.dev/blog/terminal-anatomy/
How did Zillow lose money in this market?
Ahh so it was an informed choice. I understand. But Hacker News doesn't do previews anyway :)
I'm confused here. How does a threat of deleting your data in less than 7 days and not even canceling your billing makes you a loyal customer? That seems quite awful, miss the email and your data is gone, and you end up paying without them even storing any data.
It hangs around the DNA and makes it hard for the DNA to do its own jobs. Like a really annoying and clueless co-worker.
> No they're not. Or at least they shouldn't be.

I hate to break it to you. Maximum employment is the one thing the righty capitalistic federal reserve and the lefty communists have in common. if anything the socialists are more (in theory) while capitalists are more in practice.
> I don't have to worry about swapping out LBs and Firewalls as a nightmare connectivity issue. I don't have to scale file storage regularly. I can scale up service DBs as needed. All of that reduces total complexity.

You're wrong. Complexity has increased by a huge magnitude so much so that it's actually unmanageable by a single person.

What's going on in your case is that the complexity of all of this has been abstracted away from you by amazon. They have entire teams of people making sure you don't have to deal with the actual complexity. That's the difference. This isn't an actual abstraction in the same way a high level language abstracts the details away from you. This is an abstraction where a team of people take care of you. It is not a true abstraction because you cannot wield this abstraction yourself in the same way you can wield a high level programming language.

Make no mistake, the actual complexity of it all has increased by huge orders of magnitude.
My guess is that because beauty is in the eye of the beholder, you seem to make the assumption that "antialiased=good looking, non-antialised=bad looking" but in my comments for this entire thread i claim that i prefer non-antialiased text. And i'm going to guess that anyone who would use CDE would also like it to use non-antialiased text.

Anyway, here are a couple of screenshots in the CDE wiki that says how to enable it[0]. Unsurprisingly the only comment there is about someone saying that they prefer the non-antialiased version.

Apparently there are a issues with the terminal emulator though i guess xterm would be a better choice anyway.

https://sourceforge.net/p/cdesktopenv/wiki/FontsWithXFT/
There are so many ways you can accidentally systematize racism in software like automated lending.

In the past there were explicitly racist policies like redlining. This leads to a historical data set of loan denials to people in specific racial group. If that group has other traits that correlate to their race, e.g. the neighborhood they live in then you could presumably have a model that doesn't explicitly have race as a feature but uses that historical data and some subset of racially correlated features and as a result disproportionately excludes people of that race.
The Long-Run Effects of Agricultural Productivity on Conflict, 1400–1900 [pdf]
Interesting article. It's too late now for me to focus on it but I'll check it out in the morning! :D Thanks for posting.
Was the agent a Zillow employee?
I consider him to be centrist, but it's very subjective as there is no good definition of left/right that people generally agree on. To me, he's not a partisan, so he's a centrist- not that I particularly care one way or the other.
School vs. Action-Oriented Personalities in the Labor Market
yes, they earned it. I think I said that. did they earn as much BS as they've gotten over the past two decades? no.

Google Amazon and Facebook are doing FAR WORSE things today, and no one says anything. Many readers of this comment likely WORK AT one of these places, and are complicit in the crap these companies do, yet they excuse the things they do in any one of a million ways, just like employees at Microsoft did at the time. many of those same people today still bash on Microsoft for lesser offenses than they themselves are part of, so don't act like there is logic behind any of the derision that gets thrown around.

Microsoft derisiveness today is nothing more than bird calls to help nerds find each other in the wild, but then non-nerds hear it and assume that the most common squawks they hear from the flock are true. this is what the Zune was victim to. Windows phone also, likely, which was another excellent product doomed before it hit the market because people like to tell and hear the same jokes over and over and over again. Windows Phone struggled for a while, but it too fell victim to the attitude of the commoner: "I've never once used or even laid eyes on this product, but Microsoft made it so I'm going to poke fun at it endlessly."

ever hear a joke about Bing on a non-technical TV show? that's how far this shit reaches. Bing is FAR better than anyone gives it credit for and it gets better all the time. anyone care? nope! "Bing lol"
Artemis 1’s complex launch windows and constraints
Total 1832 Documents from

- Mathematics, Physics, Sciences

- Finance, Money, Economics

- Theology, Religion, Philosophy

- Personal & College Notebooks

The collection can be downloaded here

https://github.com/Debdut/newton-works/releases/download/1.0...

Sample - The Lawes of Motion

https://github.com/Debdut/newton-works/blob/master/works/pdf...