skysight-inc/HackerNews huggingface dataset:
'Non results' from 'not good studies' are negative indicators - not 'neutral' indicators. That's they key thing to understand.

If Ivermectin did work, it should show up, but it's not.

We're doing the Oxford trial really because of some shady information and results, that could possibly indicate that there's some theraputic value. Not because people have high hopes.

Here is Merk's statement:

" It is important to note that, to-date, our analysis has identified:

No scientific basis for a potential therapeutic effect against COVID-19 from pre-clinical studies;
No meaningful evidence for clinical activity or clinical efficacy in patients with COVID-19 disease, and;
A concerning lack of safety data in the majority of studies."

While it would be good if the Oxford trials showed something, they probably won't.
Edit.. Correction..
Appeared incorrect to me..

https://www.arcgis.com/apps/dashboards/85320e2ea5424dfaaa75a...

but does not include asymptomatic etc cases never reported
What should happen when someone violates the legal protocols in which they're controlled?

Meth is already legal, in actuality. It's just controlled in production and distribution and only available by prescription. There are millions in America taking legal meth right now.
Woah, very cool - I guess Distributed Objects is getting a facelift and making a comeback. [1]

What's old is new again, as they say.

[1] https://developer.apple.com/library/archive/documentation/Co...
Slightly off topic but I've run into the opposite extreme with in the corporate world. A few years ago the company I was working at was acquired and we were all eventually migrated over to new systems like Office 365, Teams and Workday. From that day onwards it was like profiles were frozen in time; we couldn't change anything on our own and anything we could get updated through the proper channels would eventually, and inexplicably, be reset to what it was when we migrated. Contact information, who was managing who, job titles, everything. Even our previous CTO, title intact, was stuck reporting to another CTO in the system.
Interesting, I never paid attention to that. I would guess the number of singles/couples earning $40k/$80k total per year or less and own enough stock to get material dividend income must be miniscule.
postgres takes a lot of design inspiration from Oracle, but AFAIK has never made any real attempt at being strictly compatible with it.

You might be thinking of dblink in oracle's world, and foreign data wrapper (fdw) in postgres, which at least lets you transparently interact between the two for just DQL. DDL, procedural logic, etc definitely differs.
> Can you have a cooperative with limited liability?

Yes, in the US, at least.
A coop can be a corporation or LLC (and a coop that is either the former or the latter when taxed as a corporation has special tax status with the IRS, under subchapter T, so occasionally they are referred to as “T corps” analogous to C or S corps.)
tl;dr I guess what I'm saying is that even though I'm in the office, having the choice to be there makes all the difference.

I've been going into the office a few days a week because my infant's daycare is nearby and it makes logistical sense. I am also double-vaccinated and wear a real mask with care. On most days I am the only person within 36 feet. I have repositioned myself near an air vent to take advantage of a positive pressure zone around my workspace.

I say this not to argue for the office but against it, I have personal space and I'm making this decision because its a rational one for my family and productivity and carefully mitigate my risks with my behavior. I think I'd immediately be unhappy if my employer compelled people to return, particularly before I am able to vaccinate my infant. In a giant open-plan building, it's suddenly possible to do intense focused work because it's an an appropriate occupancy level.
In the sense of the point I'm addressing, yes. "Zuck is pretty successful at things he wants to do." Facebook is a thing he wanted to do. It was a success. (And a big one, but just because an elephant is very large for an animal means that it counts as 3 animals.) I just want to know what the other things are.
From what I've understood they're especially been enforcing it for Oculus.

That said there are privacy controls. You interact with other Oculus users through a customizable username. And your Oculus activity can be set to be shown to "Only me" (or Oculus friends, or FB friends, or public).

But FB themselves are obviously still collecting all the data they can.
Why should it necessarily have anything to do with customer price sensitivity? No matter what the price point is and what the manufacturer’s margin is, the manufacturer will increase their margin by putting in ads. It doesn’t matter if it’s a $200 TV or a $10,000 TV.
hey we should be friends, i am gonna think about this more. i kinda figured there was a major shift. maybe ycom will get an onion link
True. He was probably making 8 figures under ZeniMax
Debt owed to your neighbor is usually bad. You deprive them of resources, and the math is zero-sum.

Debt to your bank is usually OK. Everyone benefits from the transaction, at least by design.

Debt to your citizens is great! Your debt limit is a meaningful fraction of the sum of economic value of the nation. Your creditors are also the beneficiaries of your spending. The more you spend, the more you can borrow, because you create economic activity on behalf of your creditors, who then have more to lend.

Debt is absolutely very different when the debtors and creditors are the same people.

Debt to other nations (if you're the US) is also great! But that's a special circumstance.
> Why would anyone be passionate about any specific corporation?

This is quite evident in the entertainment (video games, film, music, etc.) industry. It has been established that many creative resources go to companies that produce most of their favorite work.

Sadly, it is quite common for those companies to have rather diverse and relaxed ethical guidelines around crunch and overtime.
Redlining in Microsoft Word 365
It partially dictates how the company communicated with its’ employees. A remote first company is going to engage with its employee base differently, invest in benefits that respect that population more and create channels that enable an optimization of that environment. A non-first organization doesn’t need to necessitate any of that. Oftentimes remote work is the lesser of two evils; the other evil being less competitive in the job market place.
The article implied that we know the parents and genes of every California Condor due to the close track science has been keeping on the species.

So I do t think it’s fair to say that an “unknown number” of the birds lacked a male parent. We appear to know the number. It was 2.

Further the birds are not clones. Those would be healthy animals. Parthonotes have two copies of one set of chromosomes. So they’re a half of a clone. Much riskier genetics which is why they almost never survive and are so often sickly.

So I don’t think there is any way a female could establish a new population. And that population (in this species) would be 100% male so it couldn’t reproduce again through parthenogenesis.

It doesn’t sound like it would be a viable way of bringing species back from extinction or continuing our species.
Crypto-influencer Anthony Pompliano's channel temporary removed from YouTube
I mean, he put it as eloquently in his own words...

Zuckerberg: Yeah so if you ever need info about anyone at Harvard. Just ask. I have over 4,000 emails, pictures, addresses, SNS

[Redacted Friend's Name]: What? How'd you manage that one?

Zuckerberg: People just submitted it. I don't know why. They "trust me". Dumb fucks.

https://www.esquire.com/uk/latest-news/a19490586/mark-zucker...
Yeah I just avoid connecting it to the Internet, and instead use a PC I control to supply the signal.
> How much work does that take?

Especially since the original Quest didn't require a Facebook account. It required a Quest account, but it didn't have to be explicitly linked to Facebook. (It's also one reason why I still use my original Quest and haven't gotten the updated model).
Yippy – macOS Clipboard Manager
Supercompilation has also been known as metacompilation for decades.
I absolutely love when the corporate middleboxes make websockets fail, webrtc fail (which is used by virtually all conferencing software), HTTP3 fail, HTTP2 fail, QUIC fail, long lived connections drop automatically
Not at liberty to post PII, but we operate many web properties you've heard of.

TBH, they've been really fantastic about everything from the very beginning of covid. I think as more large companies get on board with this, we're reaching a tipping point where the B tier organizations are starting to realize they can use remote as a powerful bargaining chip to lure talent away from FAANG.

Most companies don't need the "intensive in-person collaboration", or whatever nonsense reasoning that FAANG is using to avoid full remote. They just need skilled efficient engineers to churn out CRUD work and move Jira tickets, which can be done from anywhere with minimal interaction.
Well then, go and argue with those people where they are. Don’t come here with your stereotyping and anecdotes, hoping for an echo chamber of “yes, we sure all hate those other people who are bad, and surely none of them would be among us, the good and right-thinking people”. This place is for actual discussions, where we treat each other with consideration, respect, and nuance.
Yeah Musk isn't exactly Rico Suave, but Zuckerberg is downright revolting to most people. He's robotic and comes off as an alien playing a human.
According to period newspapers, it very much was a problem almost immediately after public introduction in the late 40s and early 50s. Here's an example from Australia, which banned it by 1955:

https://trove.nla.gov.au/newspaper/article/71874426?searchTe...
There are so many different flavors of remote (and remote-ish) work. Lots of people (especially those who don't do remote work) think of remote work as "work wherever you want, whenever you want", but in reality there are often limitations.

Employers generally care about what jurisdiction you live in so they can comply with tax law, etc. Some employers don't care where you're at as long as your long-term residence is in one of their approved jurisdictions. Some will keep tabs on your location and pay you differently depending on where you live.

Some employers mandate a set of core hours, while others limit employee home locations by time zone, wanting workers to be approximately on the same schedule.

I've heard of some US Government workers who are allowed to work from home, but only from home. Ostensibly for cybersecurity reasons, they aren't allowed to work from hotels, cafes, airports, WeWorks, etc.

Then yeah, there's this sliding scale of hybrid remote/office work. "We're remote for now, but hope to get back to the office eventually". "We think 50/50 will be our new normal, but that's subject to change". "You can typically work from wherever you want, but we expect you to be available to come into the office for big meetings, etc".
>You're looking at $10,000 just to get your private license.

Modern tuition for college is much more expensive than this, and yet people continue to go to college. It doesn't seem to be limit the number of people as you suggest this is the limiting factor on the number of people getting license. A quick internet search shows that learning become a truck driver can also cost close to $10k as well.
Of course there's no cash on the balance sheet. If you leave it on, your competitor won't. I don't know why people continue to believe there's an invisible economist in the sky making sure that your economy will always be healthy as long as the market can do whatever it wants.

Or, perhaps we're just looking at it the wrong way. Nature has epidemics, hurricanes, droughts, forest fires. Maybe a recession every 20 years is an economic forest fire clearing away the dead brush, and a collapse of global infrastructure is just a global logistics drought. Sure, companies collapse, people's lives are thrown to the wind. But nature's cruel, right?
The Great Resignation 2021: People quitting jobs in droves
This was the one for me.

https://slatestarcodex.com/2014/11/21/the-categories-were-ma...
I literally worked this scenario. We procured extra proofer and oven capacity as compared to what we needed daily. The cost was marginal, there was some labor cost savings (less cleaning) and added resilience.

But on those busy days, the store would turnover 4-5x when competitors were out of product.
Watch [1] @ 1:08. Is it really a mystery as to why canines tilt their heads when spoken to? It's always seemed self-evident that they are hearing a sound that is of interest and they are evaluating to see if it's useful information.

1. https://youtu.be/D2SoGHFM18I
~30 year old article on how red blood cells metabolize many classes of drugs: https://onlinelibrary.wiley.com/doi/pdf/10.1002/bod.25100904...

Basically, RBCs have lots of enzyme systems that serve (in part) to protect the important parts (e.g. haemoglobin) from oxidation. Put a bunch of lisdexamfetamine in the blood, and the RBCs will gradually hydrolyze it to cleave off the l-lysine and leave d-amph.
I do the same thing
Tesla API
I really wouldn't, truly. The only way you could get me to work for somebody like Zuck (if I even had any qualifications they were after - I most definitely do not) is if he were lobbying the entirety of the US political system to advance stem cell research and pry medical innovation out of the evangelicals cold soulless hands.

Back to Carmack - if I were Carmack, had the intelligence and experience Carmack does, along with the money and connections Carmack has - I would simply find somebody not as slimy as Zuckerberg to work on VR related things with, it's as simple as that. I'm sure there are several others who would be happy to fund him if he reached out.

Do you think otherwise?
“ Also, you'd have to provide a tax shield for the losses as well.”

Not really. My car is losing 10% of its value each year but nobody is returning me the sales tax I paid for the full price. Let alone returning me some of lost value.

Why if your stock depreciates do I have to compensate you?
This seems like a super interesting feature to have as part of a language. I hope Swift can eventually become more of a general purpose language, as its actually pretty nice and they're introducing features like this that clearly targets server-side programming. However it seems right now its tied to much to just iOS development and Xcode, which doesn't make for a great experience using it for other things.
Inconstant Moon.
Market Resiliency, Capital Formation, and Investing for Our Future
Learnings form bidding $440k USD for The Economist’s NFT
yeah, the last line is quite true. I saw somebody posted a screenshot of their lockscreen with an ad. I've never seen that on my iPhone. But then with the new IOS, I've stopped all kinds of tracking and notifications.
There's some interesting stuff going on with structural editing of Lisp. I stumbled across parinfer[1] a month or so ago and it looks neat.

[1] https://shaunlebron.github.io/parinfer/
And honestly the technology isn't good enough for those masses they are now catering to. There's a reason VR commercials are so fanciful - if they showed the actual experience almost nobody would buy it.
I'd only just noticed them now (about 19 hours after this post was submitted). Went looking for mentions and found this.

I've asked mods via email.

There are a few comments in the Open Secrets thread, though no staff responses: https://news.ycombinator.com/item?id=29024032
I have a node 202 with water cooling that I built specifically to run Half Life Alyx at max specs while traveling for work. Fits in a larger ebags backpack very nicely with all the Valve Index kit. Now that I beat HL:A and am not traveling for work it sits under my TV and is pretty much a dedicated Satisfactory machine via steam controller.

Tangent—Coming out of hours of fantastical sci fi VR escapism into a nondescript hotel room in <industrial center, USA> is a very surreal and memorable feeling.
Thank you for asking this, I was having a devil of a time googling what "total" meant in this context.
This is such a lame-ass take geared towards bashing the proposed tax on unrealized gains...

It's clear enough that the pursuit of ROE incentivizes stripping excess capacity in the short term. But NIFO vs LIFO accounting is a small insignificant detail of this, and the claim that founder-led businesses are fundamentally different doesn't pass the sniff test.

First there are many businesses in logistics that are founder-led or privately controlled by founder families, from Walmart to Maersk. If founder control was really critical to setting up a business to weather a 100-year storm, you'd have expected the logistics industry to fare pretty well.

There are also plenty of industries that had to deal with massive demand spikes and did not end up being long term bottlenecks, in spite of being pretty brutally managed by markets, like grocery supplies or telecom and internet access providers.

The main difference IMO is the growth orientation. In tech there was already a large expectation of strong long-term demand growth, so there was already a structure in place to deal with capacity growth. Industries that did not have this expectation, like maritime transportation and port infrastructure, do not have the ability to start increasing the capacity on a dime.

When the profit growth expectation isn't there, evidence is the private founder businesses don't invest either. I would believe the argument more of I heard a lot more of the likes of Bezos, Gates, Page, Musk etc. investing their private money into the kind of massive infrastructure upgrades needed to solve the world's logistics bottlenecks. Until then I call BS on the argument that we should just wait for them to invest their money to solve it.

Governments might as well take it and upgrade infrastructure if the money's just parked. With the modern "golden share" structures, that shouldn't actually take a lot of control away from founders...
Consumer ISPs don't need an ip per customer. They just stick 1000 users on the same ip address behind CG-NAT
I really think there is a lot more value in finely tuning a data stack for its use case, and the people maintaining it having a more deep (if harder to get) knowledge and understanding of it. Also, them putting their product in the stack with no alternatives (one of two that don't have any) leaves a bad taste in my mouth.
If you are Erdos, it is a good decision.
World of Warcraft is actually on the wane, and has been since 2015 when Blizzard stopped reporting subscriber numbers [0]. Big WoW streamers like Amsongold have recently switched to other MMOS, mainly Final Fantasy 14 [1], in the wake of Blizzard's sex abuse scandal and many lukewarm WoW expansions. Final Fantasy 14 has over 4 million monthly subscribers, and that number seems to be growing [2]. Amazon's MMO "New World" also had nearly 1 million concurrent users in the weeks after its recent release [3].

MMOs aren't eating the world like in 2005, but they're a solidly-established genre that looks here to stay.

[0] https://www.statista.com/statistics/276601/number-of-world-o...

[1] https://kotaku.com/wow-disappointment-plus-twitch-start-mass...

[2] https://www.ign.com/articles/2015/06/05/meet-the-man-who-red...

[3] https://tech4gamers.com/amazon-mmo-new-world-registered-a-pe...
Simon Winchester is an excellent author, writes on interesting subjects (and makes them yet more interesting), and reads many of his own books in audio version. Recommended.
The conservative narrative is you're not supposed to rely on handouts.

The article is silly. Like with other socialist commentary on social spending (UBI, subsidies, handouts...) they always emphasize that it works for "most" recipients rather than how it decreases the wellbeing of every person who paid for it.
Sometimes bloaty design decisions transcend the question of programming language. Electron probably has (I didn't check) a faster JavaScript engine than Qt, but I'd expect that similarly sophisticated implementations of the same program in Qt or Electron show an advantage in performance to the former. But people use Electron because it's familiar and it's got a lot of active development, and more cynically, Google likes it that way because it means that people keep coding for Chrome (cf. Microsoft's VS ecosystem, Apple's walled garden, etc).

The problem with modern software is that vendors encourage new developers to learn using heavyweight toolkits because lock-in is profitable in the long run. One day Electron will work with Go, but it will still be a plague.
This is false. Oculus has sold millions of headsets. I mean it's not at home console levels of popularity but it's definitely no longer part of the niche gaming space.
Apple’s privacy changes hurt Snap and Facebook but benefited Google
Sorry, remind me where I diagnosed him? Or where I even claimed I was qualified to diagnose him?

What I said was that it's a concept I find useful. Whether a trained professional who was given the necessary access to diagnose him is beside the point. Indeed, any qualified professional who did examine and diagnose him couldn't talk about it like this, so it seems bizarre to me you have mistaken an internet forum comment for some sort of ironclad medical claim.

And I find the concept useful and relevant here because it helps make clear how the rarefied world billionaires live in can over time distort cognition whether or not it crosses the line into an actual disorder.
Doesn't even load properly for me, page is unresponsive
The easiest and most reliable way to expose a computer on the internet now is those services which work something like a VPN where they have an ip address and route everything sent to it over to you via WireGuard or similar.

That way you don't have to worry about dynamic addresses, ISP blocked ports, buggy router firmware. It all just works. Things like ngrok can do it really easily for http traffic.
FB is already in those markets. FB and Instagram are every bit as much fantasy land as Second Life. I agree with you that the social dynamics are different.
> Way too expensive for that, but if the price drops a bunch on that tech, that'd become an option.

You can get those cables for ~500$. It's not super practical yet, but if you can afford a 1500$ GPU, you can also add that :) Plus, you'll need to worry about cooling, noise and optics a lot less, which, on a high end build, might already be enough saving to make it worthwhile.
Consider the hubris behind a term like autoscale. You're talking about a machine that makes more machines, adapting to its environment, and all that without human intervention.

I think it's far more likely we'll just discover that, indeed, no general solution exists, and that humans must take personal responsibility for tending to their digital gardens. We certainly have a lot of spam to weed out.
Back at Sun it was Java. I wonder whether it is a great vision that will propel FB even further up, or a start of a renaming orgy and detached from reality megaprojects in a company overtaken by mid-management types and marking transitioning of FB from an ever expanding superstar into a large undead incumbent.
Say you bought a vintage car -- do you have to pay more sales tax each time the car appreciates? I know some owners of FJ Cruisers that would be pretty upset.
Amazon pays more since AWS got popular.
Probably never, doomsday prophecy in various forms has been extremely popular probably for as long as humans have been able to communicate