skysight-inc/HackerNews huggingface dataset:
Disclaimer: I'm working on a project in this space. So take what I say with a grain of salt.

There are very few projects doing anything interesting with web3 outside of speculation or "grifter" quasi-MLMs (NFTs). Until that changes, web3 won't be interesting. But, we are on the cusp of that change. Soon, there will be interesting applications on web3, and they will change the web permanently.

Two things stand in the way::

- web3 requires specialized browser plugin or even worse, a special app. You cannot do web3 inside a web2 browser.

- transaction costs and throughput

web3 requires a browser plugin (meaning not on mobile) AND education on how to use it. Those are blockers for 99% of the people, so you only have 1% of the people who will use it, and in that small population, most of them are there to get rich quick or die trying.

And, transaction costs are high for the web3 (I'm equating web3 with Ethereum). It only makes sense to participate for people who are trying to get rich.

BUT: if transaction costs go down, and people can participate in web3 WITHOUT a browser plugin, then people will start building interesting projects OUTSIDE of speculation and MLMs.

That will be the moment really exciting things start to happen.

When will that be?

If you don't know what L2 is, here is why it is important: L2 is a way to scale transaction throughput outside of the mainnet Ethereum. There are many ways to do it, but generally they involve rollups, either optimistic or ZK-proofs.

What's a rollup? A rollup is a way to do lots of smaller transactions off the main Ethereum network, and then roll them all up into a single main Ethereum transaction. You amortize all the small transactions across one single mainnet transaction.

L2 products are still in their infancy, don't work great, and have poor UI. But, they are one of many solutions to solving the transaction cost and throughput problem.

If you are rolling your eyes at ZK-proofs and saying "Oh, those crypto guys, more snake oil!" You should know that Google is using ZK-proofs to guarantee the information they pull from Android devices and processed in ML is has a guarantee of anonymity when shared into Google. There is a lot of interesting research happening despite all the grifting in crypto, so don't miss the good stuff. If you are excited about hard math, crypto has some fun work.

So, L2 will solve the "transaction cost and throughput problem."

The only other barrier is browser plugins, IMHO. The exciting thing is that L2 solutions have their own API. When one of them finallly offers a great UX for interacting with their network, you can interact with it using web2 and not with MetaMask.

Then, everything will open up. It's going to be soon.
With their track record of discontinuing products I wouldn’t dream of signing up, even if it were offered and amazing. Who knows when the rug would be pulled out from under my fiscal feet?
> most of the ones that do support it don't support more than one

Do you have any examples besides AWS?
Curious. I would claim that our current finance and legal system frequently does the very same for the impoverished or disenfranchised...

Underbanked get hammered by fees with no safety net for emergency expenses. And large portions of our population get saddled with poor legal representation resulting in de facto indentured survitude in for-profit prisons.
An apt comparison, considering Steven Donziger is in court again this week, after having basically endured a corporate-funded prosecution that has drawn on for almost three years, for the crime of winning a civil pollution suit against Chevron.

The children of every fed-level elected and appointed official in his jurisdiction and/or related to the case (house of reps member, both senators, judge, prosecutor) work for the law firm representing Chevron. No one forced any of these judges, politicians, and prosecutors to be complicit in a malicious/fraudulent prosecution. They chose complicity.
> They are accessible to a regular shareholder through the ability to sell the shares

But isn't that only true if they sell the shares back to the company in a buyback (which is essentially a dividend)? Otherwise, they're just accessing the proverbial greater fool's assets.
You've made an amazing claim, that infected healthcare workers, who, were caring for Covid patients for almost 2 years now, have been spreading COVID further. This, despite the fact that they are most likely to have caught it early as they were caring for patients prior to vaccines, and hence to have obtained natural immunity.

Please provide evidence to support your amazing claim.
These days in infosec circles simply having SMS-based 2FA enabled is now considered a no-no because of the notoriously bad (and inconsistent) security measures at large mobile carriers.
Watched a group on Twitter decide to come and burn down my neighborhood.
Watched them organize it and all start heading over.
This is a mixed neighborhood that happens to have a lot of gun right nuts. So it would have gone badly one way or another.

Thankfully the police blocked all the ways for them to get the area, but still.

After spending the entire night reporting people on Twitter and seeing nothing done. Well I
deleted Twitter. Never again.
since last April, I often find myself reminded of the talk by John cleese on creativity. Specifically his thesis that its not a talent. https://youtu.be/Pb5oIIPO62g

When having a call after another, and trying to be efficient during the day, there is just less time to be creative…
the interview i heard this morning indivcated that there's also a big unknown around whether it can induce genetic mutation (presumably in gametes). (male) participants were advised against (unprotected?) sex during the trials to prevent potential future problems with progeny.
Yes, if they put a microphone on a Mars rover, why not on an ocean going drone? A microphone deep in the water might be nice too (and I would be very surprised if they don't have those for applications in marine biology and military).
Not to mention standardised admission criteria and ICU eligibility criteria were chucked out the window in many countries when covid became a thing

Edit downvotes and no discussion. This place is getting worse
NOAA is very hit or miss with their data. I spent a lot of time this summer with the NOAA buoy data. So much of it is available and well documented. The historical and live CSV's are useful, but there is also the stuff where a column name doesn't link up to any of the docs and you have to dig through papers and reverse engineer the correct equation.

The biggest downside is the buoy's are rather old so you don't get a lot of data. Nowadays we could design a buoy that streamed back all of its raw data. But the buoys are designed with bandwidth constrained hardware so they do the analysis on the machine and return the summary results infrequently. It really limits what you're able to do with the data. Especially holding back from machine learning capability.
Right now we're running the restaurant with human cooks so staying open on weekends takes overhead – we'll be doing weekends starting with our robot launch next year!
Not exactly going to be the same thing.

Merck is applying for EUA use of this medication for Covid-19, something that Ivermectin never had. In addition, further studies didn't show Ivermectin to be useful for Covid. The study that first looked at Ivermectin has been proven to be not useful.

If another study came out opposing the Merck data, then we'd have to dig in as well to find out why, and see if either study was faulty, and if more studies are required or not.

This is how science and medicine works.

There is a large group of people that see disproving studies/claims to mean that some higher power is holding back the miracle cure. That's what happened with Ivermectin, Hydroxychloroquine, etc. This is not how science and medicine should be viewed.
Healthcare workers have been on the front line, unvaccinated, for going on two years. To mandate it or risk being fired has absolutely pissed off quite a few that I know of... My wife has gotten it, and even she is offended.

The hyperbole around this very serious situation just makes all the policies seem even more like theater.

To your second point, there was just a new report I saw yesterday that there is no difference in viral load between asymptomatic vaccinated and unvaccinated individuals.
Lets say you have a website in datacenter A

/You pay datacenter for bandwith etc.

Person pulls your website

/Person pays cablecompany Z for bandwith

Now you have to pay Cablecompany Z for the data.
I think some of that directly connects to the (intentional) confusion in terms of "smart contracts" and old fashioned "contracts". "Smart contracts" are programs and there's a sense that they are "better" and easier to "trust" than old fashioned "contracts" because computer's enforce them ("fairly and equitably", or so proponents believe [1]) and not people and institutions.

But people don't run "smart contract software" in their own brains and at the end of the day if these things are to be meaningful to people they have to interact with people and institutions and good old fashioned "contracts". It's trying to solve sociological and political problems with code, but we don't have a real world substrate for those "programs", what we instead have millennia of institutional history and contract law and at the end of the day those still matter more than what the computer says even you personally don't trust those institutions for whatever reason.

ETA: [1] Don't forget that it's a common fallacy among tech idealists that computers are unbiased and objective "because math" rather than machines that will reflect the biases and subjective opinions of those that program them.
He was at Google for 15 years. Now working on something else in finance (and he is based in Singapore).

https://techcrunch.com/2021/03/21/next-billion-users-head-ca...

https://www.arbo.works/
I thought South Korea has fast cheap internet?
That or having an algorithm incorrectly decide you are a bad actor and immediately freezing your account with no real recourse other than appealing the decision via webform only to have it denied 7/10ths of a second after you submit it.
Indeed. The opportunity for prophylaxis with an oral antiviral is also amazing.
Yes, dumb people are everywhere. Sounds like you’re influenced from cable news or social media trolls, more than you realize, however.

The doc “the social dilemma” on Netflix is a good intro to the problem.

I personally don’t trust the judgment of “us vs them” overt partisans, and think the worst are suffering neuroses. I like a good fraction of Paul’s stuff. Have no need to hear it from youtube.
Just before yesterday, I read an article here praising the "Offline First" principle. And as for everything related to software, I am reading again what was good is bad, and what was bad is good. All you have to do for a successful clickbait is to wait until someone shares his opinion so that you can finally write something against it... (most of the time, just for the purpose of saying you're against)
> ... the attackers had to perform a "SIM swap" type attack on the users

Minor nitpick: I find your framing problematic as it transfers "burden of security" to the end-users over a process that did not involve them: this was not an attack on the users - it was an attack on the telecoms infrastructure.

I have a similar gripe against "identity theft", which really ought to be "fraud against corporation X, using false identity" - however, that framing is necessary to make consumers accept, by default, the burden of clearing debts they were never party to simply because the defrauded party did not have adequately verify perpetrators identity.
Moles are difficult to see in a camera. They remain well hidden most of the time.
Disclaimer: Involved in building these sort of systems so I can go on about a lot (though not as much detail as I'd like).

At this point, most security vendors that handle email do this (or offer it). The main reason for re-writing is its device independent. A browser plugin only gets you so far, and doesn't handle modern needs where devices that have mail access will be unmanaged.

The tradeoff is yeah, the URLs are ugly. There's a balance between highlighting where the URL goes, embedding the info necessary for redirects, preventing redirect abuse, per user policy, etc.

In the end, its all really about buying time. At mail delivery time, you can only get some % of threats. Given there's a gap between delivery, and click time, you can use that to your advantage and at least prevent some % of the user base being exposed to bad stuff.

On top of it all, you have all sorts of edge cases like what to do with things that aren't URLs, but mail clients turn into clickable links. What about URLs in attachments? \o/ Time to run away.
Maybe this transmutation by nostalgia is the true miracle of Christmas.
https://www.smbc-comics.com/comic/2012-12-03
Could be god tier leet-coder with that time.
The hijacking of the successor to Web 2.0 by craptocurrency enthusiasts is sickening. No, I'm not interested in their perverted vision of the next web!
I'd think it's robust enough to withstand a couple turn overs. Capsizes, my apologies, land rat here.
I don't. I donate to humanitarian causes, as my resources are limited and I believe this is where my gifts would have the most impact at truly bettering the condition of my fellow humans.

I also believe that corporations should be far, far more involved in OSS' financing, as they are the largest beneficiaries of it while skimping on the costs. We should not even promote personal donations to OSS.
Could be in a TPM as well.
This is similar to the original Firefox extension model…

(Ug, the way autocorrect works sometimes..)
> and is this a goalpost that can ever be achieved?

It could absolutely be achieved. Literally the only thing keeping things from going back to more-or-less normal conditions right now is that there are many unvaccinated people getting extremely ill from COVID and filling up ICUs.
Thank you for weighing in. I am hugely excited about this and immediately sent a message to all my family. I know people who died because they didn't know that antibody treatments were available and effective when given early enough. I very likely saved my own father's life by helping him to get an antibody treatment when he and his own doctor knew nothing about it at the time. When we're talking about pre-hospitalization, this knowledge is everything. This pill is hugely promising and I will be following it closely.
Some interesting points on the nature of our pharmaceutical patent system... (and while the cohort in this study does seem a bit small, the conclusions appear to be fairly valid):

> "Molnupiravir was invented at Drug Innovations at Emory (DRIVE), LLC, a not-for-profit biotechnology company wholly owned by Emory University, and is being developed by Merck & Co., Inc. in collaboration with Ridgeback Biotherapeutics."

> "In fiscal year 2019, more than half of Emory's total $689.1 million in research funding came from the federal government, the university's largest sponsor."

Clearly, this patent should be assigned to the federal government, not to Merck, and anyone who wants to manufacture and distribute it should be able to do so under an non-exclusive federal licensing program. The transfer of intellectual property created by the public funds to private entities is simply a criminal ripoff of the taxpayer.

[edit] Wait, was this a three-week clinical phase III trial? Seems massively expedited relative to other phase III trials?

> "Phase 3: Just 33% of drugs make it past Phase 2 and into Phase 3, which tests the potential treatment in the largest number of people. This phase measures both safety and effectiveness with many volunteers, sometimes thousands. Phase 3 trials last from one to four years."

Trial began on Sept 2 2021 apparently?

1. https://www.clinicaltrialsarena.com/news/merck-ridgeback-mol...
Rational Wiki is one of the most unintentionally funny and ridiculous sites, given the name. It's probably one of the least reliable and credible sources of information on the internet due to the juxtaposition, a la DPRK's name. It's Pathos Wiki. [Something something Conservapedia, stare into abyss, etc.]

For some reason, it seems there are basically no nominally-neutral websites, forums, or news outlets that exist. (That I'm aware of.) I don't mean neutral; of course nothing is or can be perfectly neutral. I mean it seems no one is even attempting to be neutral or even attempting to portray themselves as neutral. There is no concept of an anti-agenda agenda.
In this kind of web, it would also be quite possible for a single developer to run a site as big as Youtube without needing tons of up-front cost. Bandwidth is free from the perspective of the site developer, and doing some small finite amount of video conversion work for the network before your video starts playing could also be built into the smart contract. Not all problems scale well this way, but video conversion is embarrassingly parallel at the keyframe level AFAIK. Conversely, the site operator could just calculate the cost of running video conversions in AWS and spread this cost out to all users by increasing the page view fee slightly.
My point as well - pumping craptos is sickening.
For me that period was like a new Universe for learning: I discovered so many new things that I never imagined.

Now I discover new things but - maybe because I am older or I have a better imagination - I dont have the same awe or wow factor of discovering a new type of knowledge that I never even dreamt about like back then.

So I am wondering will web3 bring something like this?

Of course it could be nostalgia and I probably see that period through a magnifying glass.
This is not my field. But if there is a pill that can reduce death by 50% from the virus, I would like to know more about it.

> Bright's concerns that similar drugs in its class have mutagenic properties

As a layperson, this instantly raises a red flag in my mind. Should I be concerned? Why, or why not? More importantly, where can I find research that elucidates this for me?
I did not find it outside of Hungary, yet, but there they have a mustard mixed with horseradish[1].

Since this type of mustard is unknown where I live, I tried to recreate it, but never achieved the same balance as in the commercial product, which is sad, because, in my opinion, it's a match made in heaven! It may be, that they use a milder mustard, than average, to balance out the hotness of the horseradish.

[1]: https://www.univer.hu/en/products/mustard/horseradish-mustar...
Learning Common Lisp to beat Java and Rust on a phone encoding problem
Healthcare, banking/finance, cars, telecom – it seems like every time a big tech "disruptor" enters a highly regulated industry they get a healthy dose of reality.
The Language Server Protocol alone, which was invented for VS Code, was innovative enough that it's now being used by other major editors and IDEs.

Sure you might get slightly better performance with some other program but you won't get all the features or quality of VS Code with that (and for free).
Something extremely frustrating about virtually all reporting to date is that I haven't seen any statistics as to infection and reinfection rates among front line workers. The implication is that immunity post exposure/infection doesn't exist, but I suspect that this data is being deliberately withheld because it would suggest that frontline workers don't need vaccines, or at the very least don't need a mandate.
I doubt it, but in any case, I certainly hope not. If anything, I think we need to reverse the trend of consumers gobbling up content directly created by other consumers. Getting information from your personal network of social media friends rather than from professional scientists, reporters, and investigators is bound to lead to worse information. Getting entertainment from whoever is most popular on TikTok these days is almost certainly bound to be worse artistically and probably even less entertaining than professional content created by real production studios. Just as watching your friends play basketball in the street is a worse product than watching the NBA.

There are always tradeoffs, of course. Content produced by people who don't get paid to produce it is certainly cheaper. And being a middleman who gobbles up data and sells ads is cheaper than being a content producer.

Ideological tradeoffs, too, of course. You have censorship on one side and curation and information quality on the other side. Unfortunately, I don't think very many people on either side of this want to acknowledge that there isn't a strict ideology we can just adhere to all the time and say one of those is more important than the other. Resisting censorship is probably more important when you're living under the Khmer Rouge, but when you're living in a time of abundance where the motivations of most information peddlers is solely to sell something to you, curation starts tipping the scales. This is going to be constantly changing and there is no fixed answer.
Aledade | Software Engineer (many roles, see link below) | Remote USA | https://www.aledade.com Note: We are hiring for multiple positions for Software Engineers, Senior Software Engineers, Tech Leads, etc, due to a massive expansion in our business.

While we are looking for "T-shaped" engineers, heavy front-end experience is not required. I personally only work on the back-end writing Python and SQL and never touch the front-end. Thanks for listening, now for the canned stuff...

"Aledade is a leader in population health that is using innovative, value based solutions to transform the way physicians interact with their patients. We are on a mission to change healthcare for the better and solve complex problems within the healthcare system.

We're looking for a Software Engineer to help develop our web application, which helps deliver the right care to the right people at the right time. A Software Engineer on the Aledade engineering team is primarily responsible for expanding, improving, and maintaining our existing web application. We're looking for our engineers to be self-starting, and proactive; they are expected to serve as a trusted resource on the business logic in place as well as our system architecture. They are expected to work collaboratively, with minimal supervision, to ensure our application meets our users' needs, as well as project requirements and scalability characteristics."

On a personal note, my time at Aledade has been wonderful. The people I've worked with, both on the tech side of the house and the "in the field" employees have all been very knowledgeable and genuinely care about our mission. Our CEO and other leadership are VERY knowledgeable and genuinely care about the people in the company, and the transparency is like no other company I've ever worked for.

Our tech stack consists of Python 3, Postgres, Snowflake, DBT, Flask, and moving from Angular to Vue for you lovers of pixels.

Please feel free to reach out with any questions and/or a resume if you're interested, and I can submit your resume as a referral. Unfortunately due to the nature of the data and our work, we are only hiring people located within the U.S.

pmiller@aledade.com
https://www.aledade.com/current-opportunities