skysight-inc/HackerNews huggingface dataset:
I don't have time for a full rebuttal, and it may well be true that medication is a worse approach to ADHD treatment than behavioral therapy. However, I want to point out by example that science is not true that "science clearly says" this.

---

1. "At the end of 14 months, core ADHD symptoms were reduced more in the children treated with stimulants than with behavioral therapy. However, at the end of three years, 'medication use was a significant marker not of beneficial outcome, but of deterioration. That is, participants using medication in the 24-to-36 month period actually showed increased symptomatology during that interval relative to those not taking medication.'"

If you actually look at the data, it shows that all participants (behavioral, combined therapy, medication only) showed marked improvement at the end of 14 months, then deterioration from the 14 month improvement at 36 months.

In conclusion, all participants showed improvement at 36 months versus their scores at the start of the study.

Additionally, they found that a number of participants who begun in the the medication group stopped using their medication after 14 months (down from 90% at 14 months to 70% at 24-36 months). Whilst, on the converse members from even the behavioral and community care group begun to use medication through out the study (up to 40% in the behavioral group. 60% in the CC group).

Their conclusion says it best: "It would be incorrect to conclude from these results that treatment makes no difference or is not worth pursuing.... medication management-may only make a persistent long term difference if it is continued with the same intensity as during the MTA's initial 14 month period".

----

2. "At the end of six years, medication use was 'associated with worse hyperactivity-impulsivity and oppositional defiant disorder symptoms,' and with greater 'overall functional impairment.'"

As compared to whom?

--------

3. "Within 21 months, 11 percent of children treated with a stimulant for ADHD developed 'psychotic symptoms.'"

ADHD is usually treated at the same age when psychosis is first diagnosed. It could be that ADHD symptoms are positively correlated with psychosis.

A close reading of the paper might actually provide that data.

Even if the side-effect does exist to some degree that does not mean that it is "clear" that the drug isn't beneficial especially considering the 89% of children that didn't experience this side effect.

Traditionally, what is done is more work into identifying those who could suffer from damaging side effects early and shunting them out of a medication program.

----

That's about all I can do now, but essentially there is no indication that stimulant medication is wholly poor performing and that early studies indicating efficacy were flawed.

What there is is evidence that side-effects exist, and preliminary investigation into the degree and distribution of those side-effects.

Additionally there is strong evidence that medication use is variable amongst participants versus other drugs for chronic conditions where drug use is sustained.
All the photos you directly post to Google+ are in a "Photos from Posts" album, which will grow quickly out of control for people who take more than a few pictures. There's no chronlogical view of Picasaweb photos, not even anything like Flickr's Archive feature, which is more geared toward photo-a-day projects than toward nostalgia. You certainly don't have anything like Snapjoy or OurDoings to automatically organize a backlog of hundreds of photos.

All this is true of Facebook as well, and I think it's by design. Nostalgia is often a solitary activity. What social networks want is interaction, so they're going to steer you toward whatever's been uploaded/commented on most recently. Interaction is what grows social network usage.
I think you've missed the point here: without patents, we'd devise something else to protect drugs. It's not the case that just because you can reverse engineer something, it's good for society that you're allowed to copy it. At least in the current system drug formulas are freely published, and we don't make everyone jump through the hoop of reverse-engineering.

The argument is essentially "new medicines are good for society but expensive to develop, drug companies will only spend the money to develop new drugs if they can make a lot of money on the successes, drug companies won't make money if other people can copy the successes."

If you remove patents, we'll have some other law to give drug companies their profits. Probably something along the lines of the DMCA, which effectively strengthened copyright to deal with technological developments, but was a huge step backwards in terms of what interested parties could do with copyrighted material.
git pull?
I disagree about the keyboard. My thinkpad's laptop is much more confortable for me than full sized keyboards.
Presumably it would be a stripped down version of Mono. The .NET Micro Framework is about 300k, for example.
I've visited FreeFileSync site on SF and didn't get it. Does FFS support non-interactive ("daemon") mode, where it runs in background, monitors filesystem for changes (using inotify or similar mechanism) and propagates them to one or several remote systems. (I've highlighted the key points.)

AeroFS and Dropbox are not as simple as inotifywatch+rsync. They don't only offer synchronization, but replication and version control.
True Blood - Season 4, Episode 8
Thanks for come back here!
Now, I'll tell you show summary of True Blood Season 4, Episode 8. That title is Spellbound. Maybe you'll think that episode will many people spellbound, lol. So don't guess what will do them on that episode. For get more script be better, let's read the one paragraph under here.

True Blood - Season 4, Episode 8 "Spellbound" will be airing on Sunday 14 August 2011 at 9:00 PM, HBO
Why not use free PicasaWeb for this? $5 gets you bbasically unlimited storage.

The only answer I can say myself is that PicasaWeb uses the ugliest possible lossy compression settings on all photos it displays.
I've seen a number of conference organisers complain of this so it must happen often!
I think once the IDE catches up to the level of Visual Studio or the Java stalwarts Eclipse/IntelliJ it will really take off. I usually do my stuff first in VS then bring it up in Monodevelop to finish it off and make sure I am mono safe.
Your need is very unique and it's something you only do once in a while.

And yes, you can delete all the photo at the same time using organizer, or you can use the API to write your own delete method.
Your experience is yours. How long have you been on medication? What medication specifically?

I've heard that some new meds are not stimulant. They might be good. But the old Ritalin/Adderall stimulants have quite possibly caused the psychotic symptoms you are talking about. That's what they do.

Are you familiar with street meth? Ritlain/Adderall are pharma grade long duration forms of that. They have made me crazy before. And they don't "Halt Depression" they get you so busy you that you won't reflect on yourself.

Artificial increases in motivation are silly. If you aren't inspired on your own to do something, you probably should be doing something else.

Stimulants are much less than perfect and throwing out a pharma grade street drug with the bath water is fine with me. It's drugs or it's not.

There are ways to handle ADD/ADHD without drugs. Change the environment. Forcing kids to take meth is just wrong.
Install Etherpad Lite in one minute on Windows
1) Download this zip (10 MB) http://etherpad.org/etherpad-lite-win.zip

2) Extract the file

3) Double click start.bat

4) Open your web browser and browse to http://localhost:9001

You can find Etherpad Lite on Github here -> https://github.com/Pita/etherpad-lite
I really hope it isn't.

As someone who enjoys tinkering with hardware, having access to the internals of a computer that desktops afford is just plain fun. I've never experienced the same with laptops, which typically require jumping through flaming hoops just to get the case open.
It may be my honeymoon period, but plenty of others who are well past their honeymoon period and still enjoying the benefits of stimulants.

Again, it's not a perfect drug, but it works if you use it as a tool and not as a silver bullet.
I think a good rule of thumb is lay your intentions out there ASAP, and give the company (and your co-founder) the time it needs to adjust to your departure, within reason.

At the end of the day, this is about you. If you're leaving to do something that will make you happy, no one with sense can hold that against you.
Kinectasploit: Metasploit + Kinect = LawnMowerMan
So the simple answer is that right now we use a most recent wins strategy because our data is not critical or highly correlated like relational data. For us it’s simple to add at a future date UI features to allow wiki style history. Obviously with correlated data it’s not so easy :-) and that is, as I believe you were implying, where versioning gets tricky! Of course point still applies about the need to avoid mutation :-)
With regards to what content auditing is, there's a freely downloadable guide to answer that:
http://www.pagetrawler.com/content/working-with-content-inve...
Valid point though, more explanation would be handy.

There have also been a few requests for an example of the results before we ask people to get stuck in, so I imagine that'll get done soon. This is an Alpha, and there is lots of functionality and deeper / more valuable results we want to provide - any feedback is good feedback.
That's their business model. Yahoo is a media slaughterhouse, not a farm.
1) Ok. I'll agree to that.

2) HDTVs suck as displays when you are doing anything other than presenting content.

3) External Hard Drives take up about as much space as internal hard drives, but you have the option of where you would like to put them. How is a desktop with 2 big drives more convenient than a laptop with an SSD and an external drive?

4) Apple's laptop lineup is purely sandy bridge now, and those processors scream.

5) My Desktop is thrashed. Tons of dings and dents from my chair bumping into it on the floor. Also, whenever I need to get to the cabling at the back, I pull the tower forward, and then push it back when I'm done. Sometimes it catches on my desk and I get a huge scrape across the side.

6) My Macbook Air has the exact same keyboard as my iMac. Both work great. I don't do data entry so the numpad isn't necessary.

Overall.. this article is a shot from the hip attempt to attract attention ("dammit"). It lacks substance though.
I remember reading the original paper years ago. http://www.recolored.com/ is based off that research.
Samsung Galaxy S2 launches finally in US on August 29
I was on 14.0.835.2 (Win7) and had a similar issue (black box, and very laggy scrolling). Once the GPU compositing and GPU accelerated drawing options marked out here [1] are disabled, the issues went away.

[1] http://i.imgur.com/COxPY.jpg
Of course not. It just isn't the only game in town anymore.
Firefox's Mozilla Foundation is probably the most valuable non-profit in the world right now.

Boy they have leverage.
Blackest Planet Absorbs Nearly 100% of Light
I don't think it's the buttons so much as the lack of context. Google profiles aren't used in the same way facebook or twitter accounts are.

Once I looked at my google profile, saw the +1 section, I understood immediately. But I still don't care much because nobody looks at my google profile including me.
Out of curiosity, what are you getting out of Eclipse that you'd like to see in Monodevelop?
1988 was the heyday. It was still a 'miracle-drug' at that point. I was the experimental group.

They dialed it down after year or so, although I didn't notice much change.
Three questions:

1) How much would 8g of Thorium cost? How much would the engine cost? Even with economies of scale, I can't imagine that it won't be an astronomical investment.

2) Could enough thorium ever be produced? Can it work on a North American ~1car/person scale?

3) Finally, is this _really_ a good use of the technology? Isn't it better to just drive less, use public/bike/walking for transportation, live closer to work, etc?
Geek Technologies That survive 25 to 50 Years Later
Probably wrote that on his grampa box.
Found in the Reddit post.

Gentlemens Hairdressing, 22 Scotland Green, Tottenham, Great London N17 9, UK

http://www.reddit.com/r/reddit.com/comments/jcx89/aaron_bibe...
Have a look at Openphoto, it's an open source (kickstarter funded) option to do exactly what you're talking about

http://theopenphotoproject.org/
(Sorry, I thought I ninja-edited quickly enough.)

How serious is the admin and financial outlay? I want to say that it would be worth it to avoid the risk of Paypal freezing your funds (or worse), but that's a hard call to make without knowing exactly what the costs would be.
Just like XMLHttpRequest failed because it wasn't part of "the open web"? Except it didn't.

Or all of the Google Gears features that became HTML5 features? Or any number of other examples.
Is your ISP cheating you out of bandwidth? New gov't test offers a hint
Ask HN: Who is funding Thorium/power gen startups?
People have been talking about Thorium reactors since near the beginning. The governments of the world seem wholly uninterested in funding this.

Are there incubators/VC who are funding energy research who aren't scared off by the "nuclear" label on some processes?
I do not think you are crazy at all... you were freelance and started the company because you like that sort of thing, presumably, and now that it is more stolid it does not have any appeal. It happens a lot.

That said you will want to handle this professionally so that you do not burn any bridges. You have sold one company and may want to do it again so you will need a reference there.

I remember reading that when Jim Clark wanted to leave SGI (prior to founding Netscape) he spent about 6 months working it out. Obviously your situation is different but you may want to pickup his book Netscape Time and read the sections on his exit from Silicon Graphics to see if there is any advice there that you can use.
My apologies. I considered doing so, but I thought "More on Software Patents" might not be a sufficiently informative title.
There have been studies of that. Very few normals change search engines.
I was thinking the same thing re: google influence. Also, was it any wonder that at a photowalk attended by a ton of Google people, Google+ would be talked about more than Flickr?

He makes some good points about the interface stagnation and community excitement (even my own Flickr account has grown weedy and sparse over the years.) However, it was off-putting to see so much, I don't know, what seemed like personal vitriol next to evaluations of the service itself.
What are you saying, that people should build corralled pens for children so that they can 'thrive' on their natural ability to bounce from left to right and generally moving about a lot but accomplishing nothing?

Your appeal to emotion argument is detrimental to all those who are (through prejudices like yours) denied treatment for what is an actual, physiological brain defect. 120 mg is a lot, it may have been too much for you, or you may not have ADHD, I don't know. But denying that a disorder exists because you had a bad experience is intellectually dishonest and holding back the treatment of hundreds of thousands if not millions, and social acceptance of treating it.

The science is clear on this point: ADHD exists, it is treatable, and the quality of life of people who have it is improved significantly with medication and behavioral therapy. That methylphenidate works has been widely proven scientifically, and its effects have been studied for decades. It's true that we don't know everything about it, and we will need further studies for decades, but that doesn't take away from the dramatic improvements in functioning that many people get from it.

Your 'argument' seems to be based on 'But I was not myself.'. I'm sorry that you apparently feel that there is some sort of mystical 'true self' that is somehow different when your neural functioning is chemically improved, and I hope that until you come to terms with reality you can live a productive life and be generally happy. But until then, don't be the crab at the bottom of the bucket.
Our Go-To-Market Online Marketing Strategy
> What benefit do I get from +1'ing something?

The link shows up on your Google profile, in the "+1" section. It's would be fairly convenient way of sharing bookmarks, if anyone used Google profiles.
"I was actually surprised that MS didn't approach Firefox with a better offer right now."

Do you know something we don't?
It's been clear for some time now that, among top developers, Github has started replacing the resume. Work for Pie seems like a convenient way of getting -- at a glance -- an idea of the quality of a developer's Github profile.
I've kept a diary of sorts most of this year. Every night before I go to bed I try to fill a notebook page with all my thoughts from the day. Think about what I want to do tomorrow.

What I ended up doing by mistake which I really like is that when I get to the end of a diary, I have usually written only on the front side of pages. So I start writing on the back sides of the pages and I watch as my life unfolds in reverse. I can see how I felt yesterday, then 3 days ago, then 5 days ago, and then it gets to several months. And I am looking back on how I thought/felt and seeing all these patterns. You start looking at what you wrote in a different like. Patterns, like maybe a person in your life being sad often or a certain idea that you keep writing about, start to really emerge clearly.

I think it is a worthwhile habit if you want to understand your mind. It also helps me sleep most of the time by letting me get stuff out of my head.
Shameless plug, but I coded up http://www.crimesagainstcode.com a little while back as a learning exercise that lets you manipulate QR code pixels like this. No logo image injection but you can "draw" whatever you want
As long as you keep it within the error correction you can do whatever you want.

(it's admittedly not very robust, I have a lot more ideas for it, but my time is scarce and my site metrics haven't really shown there's enough interest to put a bunch of time into it -- feedback is welcome though).
Or you could just see it as an efficient accelerator (duh).

An accelerator that speeds up the the rate of 'new business' failure.

The upside is that resources can be pooled in to a pinpointed funnel of repeatable goals. The downside is the mechanics of the model is scalable, but the quality is not.

There are competitors in every market space, to think that this wouldn't happen to 'incubators' is insane.

This is not a bubble, its business.

Not to mention that what the economy needs are good performing companies, I tend to think incubators and accelerators provide this.
There could be many reasons we're seeing a rise in the number of incubators, principally the cost of technology startups are falling (makes sense from a diversification standpoint to invest the same $$$ in 10 companies that you would in one) and as a investor/mentor you stand to reduce your capital risk if you have some say in the early stages of product development.

Investing in early stage is cheaper and riskier. Investing in later stages (when a company has traction/growth - VC/PE stages) becomes more expensive, but is less riskier. The incubator model has the advantage of managing some of that early stage risk that angel investors traditionally didn't control by having experienced entrepreneurs on-board/within a network and in a collegial environment.

Any successful model will attract competitors, so you now have more incubators. He's equating the rise in incubators as a sign of a bubble. It would only be a bubble if you had tons of incubators sitting on cash and not finding any place to invest it. His second mistake is equating failed incubators, that result from poor investment decisions/leadership, with some kind of market correction ("the bubble bursts").
How is PageTrawler or "content auditing" different from regular crawling of a website? I ran a website through and the output was basically the same as any off-the-shelf web crawler.
It is absurd.
WIP it ♪♪♫♪ WIP it good
Everyone has invites. Good is still running a tight quota and turning away people with invites.
MIPS Simulator - An IDE for MIPS Assembly Language Programming
Thanks. Some freelancing opps have presented themselves sooner than I expected. I feel like if I leave right now (even with 3 weeks notice) people will still be pissed. I'm just nervous to say "hey, i'm going to start looking for a job" before I actually have one though.

Thanks for the book rec. I will check it out.
I think headphones are unfortunate though because they are often used to drown out all the noise around - or at least this has been my experience. In my current company and especially my last one (a very well know design studio), headphones were used because it was insanely noisy. I look forward to a day where the only reason I have headphones on is because I want to actually listen to some music.

That said, I am a huge fan of cubes/offices/personal spaces. The most productive I've ever been is in those types of environments.
While I generally find myself on the side opposing patents, this article was an interesting read from the pro-patent perspective and I feel made good arguments.

I personally like to know and understand both sides because, in my experience, in 99% of cases no side is 100% right and no side is 100% wrong.
Mental health provision on the NHS is shockingly poor. Unless you end up hospitalised (which you really don't want to be), your choice is either pills or a six-month wait for six one-hour sessions of CBT. Community mental health services are massively underfunded and are struggling to keep up with even their highest-priority users - sufferers of schizophrenia and bipolar whose conditions could easily become fatal if mismanaged.
> I've seen a number of conference organisers complain of this so it must happen often!

That's not really a valid argument. You don't know how many conferences used Paypal and went off without a hitch. Not many people are going to write a blog post saying, "We used PayPal, and it went fine!" - and of those, fewer still would hit the HN front page.
Google Plus Tells Pseudonym Lovers to Shove It
How can you decouple self-image from "quality of life"? Presumably how someone subjectively feels is an important part of quality of life, not just objective things like their income levels and job security; someone who's really good at school but doesn't like themselves anymore isn't exactly having a high quality of life.

I'm not particularly up on ADHD research, but in antidepressant research this is now widely taken seriously, that the goal of antidepressants has to include improvement in subjective wellbeing, not solely reduction in suicide risk. Even if you don't care about subjective assessments (which, increasingly, psychiatrists do), there's also the practical reason that patients who don't like what a particular drug does to their personality are much less likely to continue using it as prescribed, making it important to find a match that the patient is comfortable with the effects of (unfortunately that's still mostly trial-and-error, because the effects of drugs vary a lot between individuals in thus-far poorly understood ways).

[Fwiw, I don't personally care much about a mystical "my real self", but I do think psychoactive chemicals can change one's personality---in fact that's almost definitionally what they do, to the extent that "personality" is just the aggregate of how the brain works---and that some changes can be ones I like living with, and others can be ones I don't like, so I'd prefer not to take drugs that change my personality in ways where I don't like the result.]