skysight-inc/HackerNews huggingface dataset:
Not to mention a big misconception of what a MVP is:

only after you actually have a first version (whether it’s MVP or more extensive) out in the wild

I recommend looking into: Your Product is NOT “The Product”[1] and The Minimum Viable Product Dissected[2] (its key line is For starters you must look at the MVP not as a product but as an experiment)

[1] http://www.readability.com/read?url=http://www.ashmaurya.com...

[2] http://www.w2lessons.com/2010/10/minimum-viable-product-diss...
Five Reasons to Launch Your Startup in an Existing Market
It's very harmless. Obviously there's a good number more technical details in here, but the gist of it is we take the parts of the HIV virus that makes it so good at proliferating, take out the genetic material that makes it harmful to our cells, and put in our own genetic information for the HIV-derived virus to inject into our target cells (known as a viral vector).

Contrary to the mental connotation, it's a very harmless procedure that's often used even in BSL-2 labs. It's not to say that there aren't risks involved, but chances are you're not going to end up with AIDs.

HIV-derived lentiviruses have been in use for a long time now and are a proven research tool. Coincidentally I just grew and harvested a new batch of lentiviruses this past Tuesday to treat cancer cells with shRNA.
Nothing in life is without risk, and using HIV is no exception. However, in comparison to the risk of dying from leukemia, I think it is fair trade-off.

More details: http://www.vcu.edu/oehs/chemical/biosafe/lentiviralvectors.p...
Has PPIP actually bought any of these toxic assets or is it just a plan. The wikipedia entry doesnt seem to imply anything has actually been bought.
Deolalikar’s Claim: One Year Later
NYTimes article on the sad state of National Cancer Institute funding:

http://www.nytimes.com/2009/06/28/health/research/28cancer.h...
Www.022.edu.zhongqicai.com
Yes, they do have the issue - and a lot more issues. eAthena never rewrote the client - just the server code. Some of the eA guys (ultramage is -amazing-) are very smart.
Thanks WilhelmJ. This definitely helps.
University hacked: 75,000 social security numbers, student names exposed
© 2010 msnbc.com Reprints

Ok, so what has happened after the article was printed the first time?

EDIT: ok, looks like it was just an error by msnbc. It does seem fresh: http://hosted.ap.org/dynamic/stories/U/US_MED_GENE_THERAPY_L...
How much of an iPhone is made by Samsung?
My point was more that the benefits in this case are likely not as great as I had originally thought, not that individuals or amateurs shouldn't think about it. Same thing you're saying really.
Here is what I mean by better formatted:

Table of Contents always included

No funny characters scattered throughout the text

No missing paragraphs or words

Graphics on the same page as their captions

I found I could not count on these things for books in the Amazon or Barnes and Noble stores for low cost or free books. Even more expensive books often lacked table of contents (when one was appropriate - for books with chapters or short stories). More expensive books often lacked appropriate handling of graphics - Nook is bad, Kindle is worse.

Feedbooks almost always has table of contents when appropriate, and never has missing paragraphs, funny characters, etc. Though once (out of around 50 books) I encountered a chapter that was the duplicate of the previous chapter.

EDIT: formatting
5 Trucos para Negocios Rentables
Wow, clicking your link (the google search for site:news.ycombinator.com) sure was scary, but since I kinda knew what it was about, I didn't freak out, and simply changed the encoding of the website to some ASCII code page, revealing the illusion.

HOWEVER, what I find extremely worrying, is that the URL in the URL bar remained the same all the time, with the embedded query string site%3Anеws.ycombinator.com, and IT DIDN'T CHANGE TO ASCII when I changed the encoding of the web page. Haven't they/we learned yet, that this is a very serious security issue?
Swarms and the Wireless Revolution – Connecting the dots
The difference is that your identity is not bound to the server, it's bound to your DSSID key, which resides (encrypted) in your browser's localStorage. So you can move your (public) key to any server and retain your identity.
80^16/(600 x 10^6)/(365 x 24 x 3600) = 10^14 years.
励志名言
The entire pharmaceutical industry is basically going to collapse by the end of 2014 anyway, so it's largely irrelevant. There will be much less funding for everything no matter how promising it is, unless the government steps in and reinvents the entire process. Seems unlikely at this point though:

http://www.nytimes.com/2011/03/07/business/07drug.html?_r=1
On my keyboard, it's '-a, with ' in a place that's easy to hit accidentally, and since it's combining, it doesn't print. I suspect some layouts might have OPTION-a, which would be almost as easy a mistake to make.
These slides are a great distillation of and addition to the HTML5 Rocks Native HTML5 Drag and Drop tutorial[1]. Nicely done.

[1] http://www.html5rocks.com/en/tutorials/dnd/basics
I can't understand why you think Patel's article is better. I will grant that it is well written, but the argument is practically non-existent.

First, it's nowhere near a similar argument. Patel argues that software patents are fundamentally sound, they're just implemented poorly.

This article instead argues a position closer to my own which is that software patents are fundamentally broken because they can't be implemented correctly. The assumption in Patel's argument is that it's possible for the USPTO to police software patents effectively. Thus far this has not been shown to be the case. The argument in this blog post is that because of the nature of governmental regulation, this is impossible to do effectively. After reaching this conclusion, the conclusion must be that software patents are fundamentally broken.

Patel can make an argument that this is possible, but he doesn't.
My frequencies are from this word frequency list from the British National Corpus: http://canonical.org/~kragen/sw/wordlist
Is this a new tech bubble?
I particularly enjoyed the bit where he starts with, "What we keep calling 'software patents' are just regular old patents", then spends several paragraphs discussing the history of software patents and how they've been treated differently than others.
Seconded. Being in Canada means I can't easily fly all the way to Stanford.
Uh, no. Read the agreement, no indication that pricing must match, Apple just wants 30%
This was an autopilot flight with some RC portions. Laima also included RC for takeoff and landing.

http://www.museumofflight.org/aircraft/insitu-areosonde-laim...

(She's a pretty bird. If you're in Seattle on the first Thursday of the month, you can see her free from 5-9 PM.)
Yeah, I know, I should take my question to Stack Overflow, but does anyone know how to configure FF to not try to reopen tabs after a crash? (Takes a long time on my old machine.)
When I had a Kindle, I first mostly bought free or very low cost books from the Amazon, though I checked out excerpts of more expensive books sometimes. Virtually none of them contained waypoints, and only a small fraction had table of contents when warranted. Graphics were terrible across the board (captions on a different page, not appropriately sized, etc. - try reading a Curious George sample to see how terrible it is).

If Amazon wants me to invest hundreds of dollars in buying books on their store, they're going to have to do a better job - perhaps some minimum quality guidelines.
Javascript Unit Test Environment (JUTE) Now Open
Don't forget to add "correcthorsebatterystaple" to your dictionaries kids!
The attack you describe is easy to defeat by making a small modification to the selected sentence.
Would You Believe? A VT220 Connected to a Mac Pro
My guess is they balked when the researchers decided to use a modified HIV virus to implant the new genes. If it went badly everyone would point to the HIV and the bad press could be devastating.

Thankfully these researchers were able to take some big risks and prove out the theory in a fairly successful trial.
I guess that would follow. If the client is set up to receive invisible players and not display them, then the original architecture must have been the same.

Do you have any evidence or experience to back up the "just about every game" comment? I still find that hard to believe. This is coming from having written code to "do it properly".
Oh, so someone patented a multiply linked list. That's better? It's not like there's not oodles of prior art or it's nonobvious...
> most important and disruptive inventions in the history of the world

Hyperbole much? PageRank, really? The Internet, yes is one of the most important and disruptive inventions. One companies algorithm for sorting search results. A company that's only been around for a decade or so. Search is huge, Google is huge, but they and esp their pagerank agol ain't close to being one of the most important and disruptive inventions in the world.
They've gone back and forth on this. It is a serious security issue, but for people who regularly use non-ascii characters, it's a usability issue. A blacklist might be a usable compromise, but I bet it would feel terribly confusing - in part because of font variability.
What other APIs do you use? Because I find I have far more issues with the Twitter API (downtime, poor documentation, lacking features, etc)
Trying not to be pedantic, but this is something everyone should know.

If I can pull a list of two-way encrypted passwords, breaking that is way faster than extracting passwords from a properly crypted list. Essentially it's a huge list of short (almost known plaintext) messages. If you know a cryptosystem that will resist attack in that circumstance, please share.

Properly crypted, passwords admit to local brute forcing, which is bad for any particular account.

"Recoverable" passwords, the whole list admits to statistical attacks that break the whole list.
This modification looks like "Skip List" and according to Wikipedia http://en.wikipedia.org/wiki/Skip_list is was first described in 1990.
Original New England Journal of Medicine paper on this subject: http://www.nejm.org/doi/full/10.1056/NEJMoa1103849
I do not understand most of that paper, and probably never will, but can someone explain why they propose cubes?

If I take a crate of tennis balls, and compress it, I expect the balls to first (more or less) form a densest sphere packing, and from there, I expect they will start to deform to look like truncated octahedrons (http://en.wikipedia.org/wiki/Bitruncated_cubic_honeycomb)

Those may be cubic, but it aren't cubes.

Also, since there is no unique densest sphere packing, it would not surprise me if variations on this are possible (http://en.wikipedia.org/wiki/Sphere_packing).
I probably shouldn't announce, in a forum, that using Don't Forget About Poland! as a passphrase seems like an awfully tempting for someone like me :)

(American by birth, Polish by heritage)

Speaking of the example I just presented, how much more effective would it be to include special characters within these long passphrases? Obviously the goal is to be able to remember them, but surely most if not all of us, are already using special characters for our passwords.
I am not saying that his/her statement is incorrect. I am saying that it takes one mighty coincidence for that person to get those issues due to unrelated causes exactly at the same time that person meddled with sleep.

Possible? Yes. Probable? I don't think so.
Cassandra 0.8.4 Released
Marijuana Growers Use 1% of All Our Electricity
It was nice/smart of Yahoo! to not limit JUTE's capabilities to testing YUI3 code. Jasmine is my go to JavaScript BDD/testing framework, but JUTE looks like an impressive set of tools. Bonus that it's built off of Node.js and supports testing server-side JavaScript too.
The original site doesn't seem to be there any more, but here's a (horribly mangled) version from the Wayback machine:

http://web.archive.org/web/20080922234800/http://www.rnicros...
I spent an hour last night struggling with making OAuth client calls to Google (Picasaweb). I don't think a different solution is needed; I think Google just needs to implement the IETF spec correctly and provide better diagnostics. I don't know if Google started from a reference implementation.
This does not surprise me, nor does "lack of x will kill you" and the same goes for "too much of x will harm you". Just do things in moderation, or do what you feel you need. Our bodies seem to be pretty smart and often work themselves out - so just listen to it. If you feel tired, go to sleep. If you're hungry, then eat.

For biologists and doctors, it might be fun/interesting to study but for the rest of us I think we should just use common sense and listen to our bodies. I personally abhor these "fads".
Did you try more contemporary books, like recent best sellers and so on?
We'll probably stream it via justin.tv like we usually do.
This gets into the whole "security through obscurity" thing. Ideally, you should use a password-generation system such that if the attacker knows your pasword-generation system (e.g. lines from songs) it would still be infeasible to guess your actual password.

Thats why the 4-random-words technique is good. According to XKCD, the 4-random-words technique generates about 17 trillion passwords---all equally likely.

But even with a long tail, song-lyric passwords relies on obscurity. I imagine there are much fewer than 17 trillion songs to choose from. And if the attacker knew some information about you (say from looking at your Facebook profile or your search history) I'm sure it could drastically weed out the search space.
Siege is great. httperf is also worth trying. There's a good guide at http://www.comlore.com/redist_files/httperf-quickstart-guide...
Not again! 2011 is shaping up to be a record year for the number of large attacks of this kind.
The number one issue is documentation. (sparse and often incorrect).

The number two issue is they change the API and don't announce the changes until people start posting questions asking why something is failing.

Number three is random failures with no error. (Did they change the API again or is it just a random recurring event?)
"It's a novel idea."

No, I posted about my own generator in 2005: http://darius.livejournal.com/38591.html (getting the words from Beowulf). Then Zooko or Kragen pointed out some even older system in response (I forget the name).
What I was getting at is that most(?) compounds probably exist somewhere in nature already, so copyright wouldn't apply without modification. I think that means you'd have to copyright the compound in a novel field of use e.g. "for use in treating cancer".

Further, you'd want your protection to cover many modifications, so that a competitor can't just make a change to a non-functional aspect and piggy-back off your research. Otherwise you'd have the problem that new R&D wouldn't pay off, because competitors could just devise drugs that would use whatever mechanism you discovered, even if they didn't have the same physical embodiment.

What you end up with is a "copyright" that is - in practice - a patent.

Of course, the drug companies would probably love for their protection to last 75 years!
That looks pretty great. I love the look of your front page - the only thing that doesn't fit is the line of social network buttons, but those are easily forgiven. Your privacy policy is very much to-the-point, which is nice, but (as a geek), it would be nice to know what you're doing to keep the information protected. Your Terms of Service are using the same style as the privacy policy, which squeezes it down and makes it much harder to read (no, I wasn't reading through all of it, I was just looking at that page), so you might want to change that.

Anyways, moving on to actually trying the service. Using Facebook login, it works pretty well, though slowly - graph.facebook.com hangs for quite a while. It would be nice if you could pull more information than my email address from Facebook, since all of the other things you ask for could be present in that profile. Not sure if their API allows that, though. And I continue to love the visual style.

The electronic opt-outs are completely painless, which is awesome.

So yeah; great service, completely painless, one that I will probably recommend to anyone who wants to opt-out from marketing.
The Microsoft BlueHat Prize
This is not a skip list, not at all. The skip list is a probabilistic data structure that gives expected access times comparable to a BBST. The patent covers a linked list with an extra set of links that provide a different traversal.
and why do you care?
IP is the problem. Software patents are a mess cause we've convinced ourselves that owning intangible thoughts and ideas is keen!
Also, GPS signals are certainly radio waves, so the plane is still literally "radio controlled."
I meant this type of hack tends to exist in every game that incorporates invisibility - not that it's all done the same way. Sorry for the misunderstanding.

I would imagine that the proper way of programming invisibility, is that no packets should be sent, until the server confirms the player can actually see invisible characters. As I understand it, too many of these checks would limit efficiency, though.
As for light-hearted fiction books - there's plenty. I just finished reading all 14 books in the Wizard of Oz series to my son (on my Nook). Zane Grey published a lot of Westerns as well as a few about baseball (I like the baseball ones). There's also some high quality public domain science fiction from authors such as:

Harry Harrison (only a few that he forgot to copyright)
Cory Doctorow
Peter Watts (Blindsight is awesome, Starfish is good too)

And if you like any of these, Feedbooks always suggests related titles at the end of the book that you might also like. On Kindles, these are live links for one click downloads.

Frankly, I'm amazed that the quality and organization of Feedbooks is so much better than the Nook and Kindle stores. Obviously there are far fewer titles though.
Came up with an idea (edit: wrote in generalization, took to much credit, sorry, didn't want to bore everyone with details) 10 years ago, everybody thought I was crazy for wanting to inject HIV into people. The idea I had was to treat the human immune system like a computers anti-virus software and upload treatments using the HIV virus. Didn't think the FDA would even allow something like this for at least another decade. Really believe HIV is the key to ending disease in humans, even possibly aging.

Wonder how they handled its affinity for mutation? That was the big hurtle.

EDIT: xd corrected me. They did it in vitro. Which explains how they got around the FDA.
How does one calculate password entropy? I deduced this one:

entropy = log2(symbols^chars)

But using 63 symbols ([a-zA-Z0-9&]) I get 65 bits for Tr0ub4d0r&3, not 28.
Is this 'really, really paranoid' library available somewhere?
and then you say "well, is your firefox updated?"

no more of this "i'm going to stick with version 3.6 for now because i prefer that" nonsense. there is only up-to-date and outdated. yeah, it's a subtle and mostly psychological difference, but it is a difference.
Performance gains when using Cloud Computing
Google Tells ITC Judge: Microsoft Revealed Our Secret Source Code
Sounds like there is room for some creative approaches funded by entrepreneurs in this area just as has been happening in space exploration.
Top 20 app powered by StackMob.
Of course, the flip side of this is that we're veering off into attacks where you're targeting one specific person and know a bit about how they've chosen their password.

If you want to mount such an attack, fine, but most of us are dealing with the much-more-common threat of someone who gets a file or a database of hashed passwords and wants to crack them all in one go.
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I feel like reading comprehension on HN is dropping lately, or at least that some people are willfully choosing to not read entire comments before replying. I specifically said that the patent should not have been granted.

The point is that by being misleading, the anti-patent crowd diminishes their moral standing, and makes it harder for people to take their arguments seriously. This is not simply a "linked list" patent, and anyone with any software development experience who bothers to read past the title should know that.
What is the cost of living there and the income tax rates? A 1 bedroom apartment around Palo Alto and places close to it can cost something like $1800/month. Just in rent alone you can 'make' an extra $12k-24k per year in rent savings if a 1 bedroom is $800 in Haifa.
Look at countries with strong patent protection - the US.

Look at the EU (which is less patent friendly).

Which has more innovation in software? OK, the US. But that's mostly the result Silicon Valley. And there are a lot of non-US tech companies - Nokia (Finland), RIM (Canada - not sure where they stand), SAP (Germany).

Then there's the open source stuff. Linux (Finland), MySQL (Sweden), PHP (Greenland / Canada), Python (Holland), HTML (from CERN), Pascal, ... lots of innovative stuff gets made in the EU, but the profits tend to be less concentrated.

Well, in fairness: Fortran, C, UNIX, Apache, Perl, and PostGres are basically from US. Also, the GNU movement, but why would the EU need a free software revolution when they didn't have the stifling and secretive culture of the US?
0x43E (о) is the stuff of nightmares

facebооk.com is still available ;)
This is incredibly good news. So many researchers have been looking for a way to alter the inmmune system to target cancer, and it's surprising (but also makes sense) that the solution seems to be around HIV. It's this kind of out of the box thinking that pushes forward.

And this: "this small trial involving just three patients was lucky to go ahead at all. The study was rejected by pharamceutical companies and the National Cancer Institute.".

There's a very good talk on TEDMed from David Agus, about proteomics and cancer research. He bubbles up a similar concern about limitations of clinical trials.

http://www.ted.com/talks/david_agus_a_new_strategy_in_the_wa...
This is how zombie movies start.
They're not injecting HIV into people. As far as I can make out, they are using a modified version of HIV to modify white blood cells which they then inject into the patient.
I hate this title. Does "Yelp meets Facebook" really tell you more than describing the service?
Ask HN: Is the reseller hosting market worth touching?
I've long wanted to give the managed CMS hosting market a shot. That plus basic file backup services. Is it worth my time? Why or why not?

Short plan: Automatic hosting site setup using bargain servers or cloud servers. Users with Wordpress/Joomla/Drupal hosting needs are offered managed hosting for $5-$15 per month.

Any drawbacks I should know about?
The Metroid series turns 25 this year&mdash;and matters more than ever
The Great Splintering
non-english keyboards

links
Never been, but I've watched many of the videos repeatedly. Some great talks came out of Startup School. Can't wait to watch this year's.