skysight-inc/HackerNews huggingface dataset:
> The problem in the past wasn’t that opioids existed. It was that they were being prescribed far too liberally and the risks were being deliberately downplayed.

The other problem is that addicts were either cut off and forced to, or found it substantially cheaper, to move on to street drugs laced with fentanol and poor quality control. Instead of being given sufficient rehab to get over their problem.
I'm happy your son is doing better.

But the FDA isn't your parent, getting diagnoses are hard, and it's up to you and your doctor to decide what treatment is best, not the FDAs.

The FDA is just a big organization that regulates advertising, and what can be prescribed. Every drug has risks, and the only way to ensure the FDA doesn't approve drugs that will hurt people is to make sure they never approve any drugs.
> - Telecom. The US no longer has anybody who makes telephone central office equipment. The US can no longer make smartphones.

Adtran (Huntsville, AL & just acquired ADVA), Infinera (fab in Sunnyvale, CA). Both make optical transport systems. Adtran also makes access network systems (POTS, DSL, PON, Ethernet). Adtran has (or had) some manufacturing capability in Alabama.
You just noticed?

Snark aside, this trajectory has been clear as day since the 1990s (for anyone willing to broach this question) and brazenly undeniable since the early 2000s.
no description here.

no Readme file in the github page.

no info / screenshots in the Chrome AppStore page.
Omg, looking at the user agent client hint proposal, it is a nightmare of complexity!

For such a trivial thing, you will now have dozens of headers. And one of the force of user agents string was the fact of not being "fixed" in term of format but to allow unexpected evolution.

The issue with it that worth to be solved is just the mountain of lies with browser not assuming their id but having to list all their ancestors.

Also, again something that itch my brain with a new case of Google controlled info:

<<Note the word "secure" in the paragraph above, and the SecureContext attribute in the IDL: these client hints will not be delivered to plaintext endpoints. Non-secure HTTP will receive only the reduced User-Agent string, now and forever.>>
I like how you mention that there’s numerous concerns of reactions yet link not a single one and then list a lot of unrelated points.
If you're anything like me you probably managed to save a whole heap of money as well - less eating out, no commuting costs etc. etc.
What content would a kid be consuming on IG? There is no children's content on the platform, as far as I'm aware of.
You are right about the current role. But I think the frustration with the FDA comes from their textbook following of the rules without any apparent concern for trade-offs beyond their immediate purview. Their algorithm for decision making is limited and that leads to uncreative decisions.

My personal frustration with them has been their slowness to approve vaccines (and to do common sense things like offer boosters or lower doses for those who want them) because it goes against procedure written years ago for illnesses that are not time-dependent at all.
Could a CO2 sensor do the trick?
I don't know your use case, but if you need access to a Windows Desktop you can download some ready made VMs from Microsoft

https://developer.microsoft.com/en-us/microsoft-edge/tools/v...
I've donated quite often in the past few years but have usually waited for the matching donation drives so that my donation would count more. Problem of course with that is when there's no matching donation drive, I end up forgetting to donate
>...rather than nasal/mucosal immunity which prevents infection via the upper respiratory system...

Who says?

Expansion of tissue-resident CD8+ T cells and CD4+ Th17 cells in the nasal mucosa following mRNA COVID-19 vaccination:

https://www.biorxiv.org/content/10.1101/2021.05.07.442971v1

>If there is vaccine escape (e.g. Delta) ...

The delta variant does not escape vaccines. They are extremely effective at preventing hospitalization even after antibodies have waned.
Yeah I'm going to play it by ear. If the inflation continues and prices permanently rise, $21k may be a good deal. We also might get close to the release of the Tesla Model 2 by then, along with a bunch of Chinese EV imports, so I'll definitely shop around.

I'm personally looking for a 'low end' EV as I will absolutely at no time ever need more than 100 miles of range, and probably much less most of the time. My commute is looking like 45 miles/week once we return to the office, so there's not much point in paying for more than that.
The harms of antibiotics include an immense reduction in child mortality and morbidity from strep, persistent ear infections, meningitis, tuberculosis, pneumonia, gangrene, and the list goes on.
I have a large mix of devices in my house. From WiFi to Zwave to ZigBee. I have about 100 lights, garage doors, various sensors and switches.
My configuration in HA is insane. Extremely large, with a lot of custom configs. I would say: unmaintainable. It works almost flawlessly for about 3 years.
In Australia Topical Steroids are not over the counter. I'm always surprised by how many things I can get over the counter in the US. Here we need a Drs. prescription for pretty much anything stronger than a vitamin or mild painkiller.
> I always find it funny how interested and intrigued yet abhorred so many people are when it comes to spycraft/espionage

Also having done this sort of stuff in a previous life. And it’s always interesting how people react when they find out, some people automatically just lose all faith in you. Like you’re some sort of actor, just playing a role. Some people legitimately want to know more about how it really works. I literally keep it to myself in most contexts.
The Sexism That Led to the Elizabeth Holmes Trial
Where does that statistic come from? As far as I know there were several distributors for OxyContin that were investigated for turning a blind eye to highly suspicious volumes of the medication being funneled into the mid eastern states.
> I think people should outsource their thinking to those tasked with the job ... Summary: Don't take ivermectine, no evidence it helps against Covid-19.

The Lancet: Antiviral effect of high-dose ivermectin in adults with COVID-19: A proof-of-concept randomized trial https://www.thelancet.com/journals/eclinm/article/PIIS2589-5...

The Journal of Antibiotics: The mechanisms of action of Ivermectin against SARS-CoV-2: An evidence-based clinical review article https://www.nature.com/articles/s41429-021-00430-5

Mainichi: Dr. Satoshi Omura, Nobel Prize scholar: "Vaccines for prevention, ivermectin for treatment" https://weekly-economist.mainichi.jp/articles/20210712/se1/0...

New Microbes and New Infections: Ivermectin: a multifaceted drug of Nobel prize-honoured distinction with indicated efficacy against a new global scourge, COVID-19 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383101/

WSJ: Why Is the FDA Attacking a Safe, Effective Drug? https://www.wsj.com/articles/fda-ivermectin-covid-19-coronav...
There is enough preliminary evidence to say mixing vaccine types is likely fine. Most of the mRNA vaccines are very similar formulations. I'm expecting it will eventually become recommended whenever it's the most convenient option.
I totally agree that books written by "insiders" are often not the most interesting ones. In the worst cases, you get long descriptions of organisational changes and anecdotes about the quality of the coffee machine (though I suppose that teaches us that spooks are people, too).
When it's about open source(somehow UNIXy, maybe POSIXy) compatibilty shouldn't matter(much).

Because it one rebuild from source, and it's there.

Ah, yes, forgotten concepts from long before the war

of eternal attrition.
Honestly in my experience, small displacement cars have typically gotten OVER epa estimate mpg. I had a 25 year old acura that got 35mpg easily each tank, epa estimate when it was new was like 30mpg iirc.
Nice blog.

It's not only programmers that need clear text though. Anyone who needs to work with text onscreen should have it as readable as possible to avoid eyestrain.

I think 120Hz will take off, it's already being added to high-end phones and some TVs.
> These criminals have no place in a lawful society that holds liberal values.

Of course. But now you have to be downvoted almost to oblivion (which gives us an idea of just how liberal our downvoting HN liberals are).
But introducing such a large scale change to the JVM has to be well thought out, especially when it will get to live for decades.
I didn’t give any examples with block function bodies, of course they are different from what I expressed. You changed the semantics and claim wrongness :/
I don’t think this argument works well against “Instagram for kids”. Yes some big tech companies have services that they supply that are close to feeling like essential utilities, but certainly not this, no one needs to use Instagram for kids, and there should indeed be freedom to choose what to do here for parents, kids and people without government intervention.
Russia sets to block Google docs
While being federal agents they try to spread democracy with bombs. Once they leave, the pretence is dropped and squash any organic calls for democracy and dissent with hacking.

Outraged when these countries are hacking individuals? Then also be outraged when you sell them F35s
Did these users start their usage with "legit" tablets? Would they be using counterfeit opiods if the real thing weren't so widespread?
Http.cat implements it: https://http.cat/418
It looks like they on purpose not developing new vaccine for delta, gamma, etc. and instead continue to milk the old one.

Typical MBA myopia - they don't see that with the quick production mRNA tech and the regularly emerging virus variants (seasonal Covid, flu and whatever is to come) they have on hands the perfect business model of vaccine as basically a subscription service, and instead they go the old way of regulatory capture to maximize the ROI of the current product through the vaccine mandate/etc.
From the article:

> One is what I would like to call the communication triangle. Communications can be secure, easy to use or hard to detect. But seldom all three.

Applies to the internet too.
Lol … a little of both. As I said my daughter came into heavy contact with pedo/grooming material. Nasty stuff.

I’m reviewing her devices manually and monitoring her connections via router logs.

The two work in tandem. When I see an issue with one I check the other.

Once she shows better judgement, I’ll back off and give her more privacy. She’s very young now, and does need the supervision.
I wonder what would happen if deletion wasn't an option. Like how it didn't use to be possible on Twitter. Would that make it worse? Or better, because then everybody would be in the same boat?
Yes, but the response will be slower than if you still have a large amount of antibodies already there.

How much difference does it make in practice is still being researched, and the uncertainty is the cause of the conflicting recommendations for or against boosters.
Just to clarify... it was less Hardy_Potter.epub and more textbooks and stuff for parents s who had to home school their children while losing their jobs and income... and public libraries closed, publishers not... supporting... any digital lending infrastructure before and during the lockdown (like mp3 and music industry, the industry was dragged kicking and screaming into the 21. century even when making a profit), they decided they need to compensate for the closed libraries by letting people lend freely...
This is a great summarisation of what I feel being a consultant feels like too. I often find an avid eagerness to produce the best there is, learn and adapt is a must, but once that fire goes out - like you say - you would never want to do it again.
Plaid is not a payment service at all. There's almost no overlap.

Plaid is mostly a screen-scraper of banking data. Users give you their banking credentials and plaid gives you scraped transaction history.
Because I lose my headphones about once a year, and a pair of$40 wiredheadphones delivers better audio than the apple ones. I listen to music mostly for work (I am an orchestra musician) and the extra fidelity i get from my current headphones (supra something something) is something I actually need. I have a pair of shitty BT headphones for podcasts and things like that.

The noise cancelling is nice, but I can live without it. For the record I have never dropped my phone due to the headphone jack.
But he's also clearly working towards delivering those things. This isn't Theranos-like at all. FSD is a real thing, and it's not a stretch to see it becoming Robo-taxis. What would you take him to task on? The timings? That's not a startup thing... every company has delays on timings: Apple, Boeing, Sony... the entire car industry....
They provide mostly non-overlapping features. Stripe = get paid. Plaid = connector into banking data (transaction history on a checking account, or the account # itself, for example). So, if you need to accept payments, or send money, you'd lean towards Stripe. If you instead wanted to get access to a user's financial data, such as if you are writing a budgeting app or personal financial management application, you'd lean towards Plaid.
TL,DR?
Thank you! For me, Ecto & Phoenix are required part of each Elixir project.

I had similar case with migration between languages - you want to use already used tools but for this new language. However, sometimes you can use even better tools :)
Rails 7 adds ActiveRecord:Relation#structurally_compatible?
Thanks for this writeup.

By "what is your proposed solution?" I meant to ask "how would you change the language semantics to remove this 'idiotic' footgun", not "how would you work around this footgun?" I apologize for the ambiguity.

I initially thought this specific footgun was an unavoidable consequence in languages that primarily pass around references (like Python and Javascript). But it turns out that Javascript's default arguments do "make a special case exception for when the expression that constitutes a function default is evaluated!"

https://developer.mozilla.org/en-US/docs/Web/JavaScript/Refe...
Well, the y axis is not anchored to zero.
Insider trading in Defi is rampant and unregulated for starters
Category theory seems very natural from the the programming point of view, there are things which are connected to other things by 'arrows', much like data-structures, or function call-graphs.
Immediate effects are most likely due to smoke containing large amounts of various monoamine oxidase inhibitors.
You submit a scarab report.
Double is far of from what was mentioned for Italy.
No, they were saying the practice is demanded by custom, which is precisely what de rigueur means.

There is no organization of snobby Pythonistas etc mandating that its members make fun of PHP, and even if there was, de jure wouldn't make any sense. Quite the opposite, in fact, since it was de facto required to be critical of PHP.
Been using HA for over a year now to run my Z-Wave+ network of sensors and switches. It has a rather steep learning curve but should be usable by most software folks. I feel like some of the terminology could be changed to make it more familiar and understandable, but after a few weeks you'll get the hang of it.

One warning though: If you're running it off an SD card or other small, solid-state device, your first priority should be turning down the amount of logging. Without reducing log spewage, expect your SD card to die within the first few months of use.

I can't complain too much, it's free software and I don't have the resources to contribute much right now, but there are some sharp edges you need to watch out for.
> Wouldn't it just be a different type of vector in terms of being able to nail you though?

Quite. Depends on your threat model and what you’re using the VPN for in the first place.
> Java nowadays is mostly used for business applications, where developer productivity is more important than runtime performance

While both of these things are true, they not connected in the way you imply, since Java is a pretty low level language by today's standards.

In the Java school of business app engineering, writing the code is rarely a big part of the effort, so it doesn't matter if the langugae is not very good or expressive. Java wins at having a big commodity-like labour pool of programmers, and there's a lot of inertia and stability in the platform.

There are of course a lot of people who use more expressive and creative tools in making business apps, like eg the many companies using Clojure, Scala, Ruby, Python etc for them, so it's not the only way to skin the cat.
Some countries have mandatory regular inspections for critical vehicle functionality like brakes. We will probably require EV battery checks like this as well, if the BMS / firmware is not enough to keep the battery pack safe.
Taken to task for what? Failing to predict the future?
Number one story is the lumber price crash. This is as much a curiosity as that is.
It's low likelihood that it handles that. There are so many videos of it not handling even more mundane things, like this one, or the ones showing it trying to run in to a road closed sign.
The same. I left the country about a decade ago. I don’t observe much positive dynamism when I return: grinding morass and retrograde motion. Reactionary politics, regulatory capture, graft, and naive faith in the market hold such a disproportionate sway on the levers of power. What is big is too damned big, and it crowds out everything else. The exceptions to this don’t outweigh the general trend. Consolidation in the private and underinvestment in public goods are the most striking.

From a raw cultural perspective, it strikes me how commercially uniform the country became: outside of enjoying differences topography and pre-homogenization (what remains of walkable old towns), I deeply don’t find much of a compelling reason to travel within the country due to how damned cookie cutter it feels.

I am sufficiently concerned about this trajectory (among a suit of other more significant concerns) to aim to get a second citizenship for my family.
Admittedly hyperbolic, though the tech I was referring to was blockchains in general. Maybe you know something I don't, but I always thought the idea and core of blockchains to be pretty rad.
> Same thing for the Theranos scandal. Financial regulators have done better for the safety of the patients than the FDA!

I have no idea why you think that. The FDA looked into Theranos in 2014-2015 and by 2015 had shut down everything but their herpes test. In 2012, when they started signing deals, Theranos was still claiming they were only performing research and development, so the FDA wouldn't get involved then. If a big company wants to invest in your startup with promises of future delivery of healthcare, how is that the FDA's responsibility?
Isn't the original website cl.cam.ac.uk?
Do wire-tapping laws not apply to children? That’s what you just admitted to.
Well, I walk for hours, people don't sit in a tub for that long when they are washing themselves off.
Definitely recommend CTFP: (Category Theory For Programmers)

https://bartoszmilewski.com/2014/10/28/category-theory-for-p...
Meh, speaking as a user of their new python sdk, the end result is underwhelming. I don't blame OpenAPI but the Plaid team for not putting in much effort.

For example, they want all arguments to be typed. So instead of using DoSomething("US"), they want DoSomething(SomePlaidCountry("US")). It gets extremely verbose -- for no good reason either as it just moves the runtime check in another method, it doesn't remove it. What's more, it doesn't even actually use python typings. In fact it's super incompatible with them because a bunch of their types are generated at runtime, lazily imported, using magic etc which confuses typing engines.

What would this look like it it were any good? Native python types and native enums. But i doubt anyone on their python team has worked with either, as they just reinvented the wheel.

Example issue: https://github.com/plaid/plaid-python/issues/340
Labor costs are too high. Look, once you spend decades paying pennies on the dollar for labor, it’s very hard to go back. It’s the same when people discovered free music via p2p and YouTube. How do you dial that back?

Nothing short of global war will fix this. Enter war with China where all trade is halted, and I promise you we’ll figure out how to on-shore manufacturing in a jiffy. A terrible price, but the only solution.
The FDA's biggest (only?) obvious enormous win was with blocking https://en.wikipedia.org/wiki/Thalidomide
The Proof Theory Blog
Consent cannot be bought. Objectification of the woman's body is a big obstacle to true equality.
That is absurd. 1% hydrocortisone sold over the counter is a useful medication for millions of people. The risk and abuse potential is extremely low. It isn't really addictive in the way opioids are. I'm sorry you had a bad experience but that's not a valid reason to change the system.
This one was a blast to watch from Melbourne (Florida), about 50 miles south from Kennedy Space Center. It lit up half of the evening sky, weather accommodating. Sorry for the shaky video.

https://www.youtube.com/watch?v=GHJuz-D6D9o
Google’s rumored Pixel 6 Tensor processor sounds extremely weird
I also don't get this. Most circuits are usually vacuum sealed already. Hack, I can drop my iPhone in water, let alone dust. Reminds me of old days when people used to insist that PCs must be kept in air conditioned rooms.
Rails 7.0 Alpha 1 released
I’m also an audiophile and when I want to eat well I’m using an external DAC via lightning but I would never go back to cable.

If you lose your headphones is your problem, not Apple :-) what would absolutely be implemented is a better codec for hi res BT Audio but also if there is a jack I prefer to override the internet DAC with digital exit.
> I genuinely think that linux is the best "developer" machine there is

I agree. And apparently 25% of professional developers also [1]

[1] https://fossbytes.com/linux-market-share-among-professional-...
One day in the future, people will be amazed out how forward thinking our society was circa 1999 when they planned status codes for IoT devices that wouldn't be invented for another 20 years. "Oh if only society now could be as wise forward thinking as people were back then. Planting seeds in gardens they'd never get to see."
Yeah I'm not seeing how 4x in price is "due to inflation" it might "contribute" or something but I find it hard to believe.
Searched the article in vain for any reference to management cybernetics or the viable system model (VSM). The models referenced here are fine as far as they go, but in the end they’re not much more than bullet points, lacking somewhat in interesting structure.

Video of my recent webinar on a model integrating VSM with things more familiar to people in product development: https://blog.agendashift.com/2021/09/10/up-and-down-the-deli...
I've found a can of clean compressed air to work pretty well for this, with less risk of damaging the contacts than with a sharp object
Not enough time has elapsed to say, but it certainly does appear to put immunity back up to original levels, which were against wild-type, even though delta is worst.

https://www.nejm.org/doi/full/10.1056/NEJMoa2114255
Most people think of Linux as GNU/Linux. But of course you are technically right.
A Man Behind NASA and DARPA’s Warp Drive Programs