skysight-inc/HackerNews huggingface dataset:
I do agree that we should re-examine the nature of opioid prescribing, but at the same time I get worried when journalists start demonizing opioids altogether:

> Yet it turns out the FDA never had reliable scientific evidence supporting the claim of safety and efficacy of opioids for chronic pain

Opioids should be prescribed with great caution, but I don’t think you’ll find anyone well-versed in pain management who questions their utility in severe cases.

The problem in the past wasn’t that opioids existed. It was that they were being prescribed far too liberally and the risks were being deliberately downplayed.

We need more evidence and more regulation, but let’s not have the pendulum swing too far in the opposite direction. It’s already common to hear stories of pain patients being forced off of their stable opioid prescriptions because their doctors are concerned with keeping their numbers down.

I look forward to the day that we have better medications for pain management with less abuse liability, but until then we need to work with what we have. Regulate and educate, yes, but demonizing the substances isn’t the solution. They have their place when used correctly.
The loss of sales will hurt more than the extra revenue per sale will help.
Talk about missing the point - it's already the #2 cause of death until 34. And we're just starting socials dependence.

To understand what's coming, note that 25% of US women are on psych medication, and growing rapidly. That's double the rate for men.
2 weeks ago, it became a felony in Texas to pay for sex. Unlike most of the other batshit laws passed in Texas this year, this one had wide bipartisan support.

As a gay man, while this is just anecdotal, it seems to me that the dynamics of gay prostitution are very different from most straight prostitution. I used to think it quite sad to hear about gay men paying for sex. I mean, these days, it is extremely easy for gay men to find other gay men to have sex with, for free, as long as you're willing to have sex with guys who generally look like you do.

Then I had some friends who had escorted at some point, and they explained the dynamic. Quite simply, many of the "johns" were older, and they basically wanted a hot, younger guy to have sex with them (of course there were other types, for example closeted men).

None of the guys I knew who escorted ever felt coerced into doing it, beyond the fact that they needed money, and to them it was an easy way to get money.

Of course, I'm sure there are guys who did feel pressured into doing it, and sex trafficking does occur.

But there are still many, perfectly consenting adults who pay for sex as part of "the world's oldest profession". We should stop this moral panic and focus laws to help actual victims of sex trafficking.
I wonder if the Sega Fusion emulator supports it? http://www.emulator-zone.com/doc.php/genesis/fusion.html
For a while, women in Afghanistan could be educated and visible in public again, like 70 years ago.

If you choose not to intervene, you have still made a choice.

"Never Again", yet Rwandan genocide, Serbian massacre, Uyghurs in camps, Darfur, Syria, Daesh, Qatari slaves... whether you intervene or not people will suffer.
https://support.google.com/youtube/answer/2902117?hl=en#zipp...

"This option mutes just the claimed song. Other audio, like dialog or sound effects, won’t be muted. "
Low interest rates don't increase inflation do they? And rocketing stock prices are definitely not a part of inflation.

QE and stimulus can certainly contribute, but "as much" is a pretty big overstatement. If anyone thinks inflation was a notable fraction of the price quadrupling, they're being ridiculous. Even a huge amount of inflation would only be 2-4% of the lumber price increase.
I really really wanted the Google phones to succeed, but after following a similar path with 5 completely broken phones (across 3 models) I've lost all hope. At one point with the 5X
Google replaced my phone with another 5X that bootlooped within a week of receiving it.

So I begrudgingly switched to Apple. I haven't had a single hardware problem with my family's phones since. I will never pay for another Google phone. In hindsight I can't believe I tried again after the second time.

It's embarrassing that Google is continually having these significant hardware issues. Ultimately Apple didn't sell me on their ecosystem... Google did.
Having read Empire of Pain: the Secret History of the Sackler Dynasty by Patrick Radden Keefe, which heartbreaking and outraging- one of the biggest surprises for me in that book was how the Sacklers literally hired and FDA commissioner who approved their submission to come work for them:

> Richard Sackler, in a sworn deposition, said that [FDA commissioner] Curtis Wright had actually started calling Purdue about a job before he even left the FDA.

And then he left the FDA and got a $400k a year job at Purdue (in 1995 $$, so ~700k/year now).

Incredibly outrageous how the Sacklers got away with a hand-slap and litigation shield after looting all assets Purdue and declaring bankruptcy.

Highly recommend that book if anyone you know has struggled with addiction or if you just want a really gripping nonfiction read. I found it as well written and in-depth researched as Bad Blood by John Carreyrou.
Medical researchers can be pretty amazing, yes. But you sound like it's an unsupportable idea?

Here's examples drawn from https://scholar.google.com/scholar?as_ylo=2021&q=vaccine+con...

"increasing global vaccine availability will be a significant boost to efforts to contain COVID-19" - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321695/

"Understanding whether members of the university population are willing to receive a future vaccination against COVID-19 and identifying barriers may help public health authorities to develop effective strategies and interventions to contain COVID-19." - https://www.mdpi.com/2076-393X/9/3/275/pdf

"With the United States Food and Drug Administration (FDA) approval of two highly effective COVID-19 vaccines from Pfizer-BioNtech and Moderna, we now have a novel approach to contain COVID-19 related morbidity and mortality." - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944369/

"Although the use of COVID-19 vaccine may contain the transmission of SARA-CoV-2, control measures such as the use of masks, physical distancing, personal hygiene, testing of exposed or symptomatic persons, contact tracing, and isolation are still of pivotal importance in protecting personal and public health against COVID-19." - https://link.springer.com/article/10.1007/s12250-021-00408-5

"We anticipated fears in the larger part of this community that health experts need to address through reassurance of the community that vaccines are tested and that they are safe and important if we are to rapidly contain the COVID-19 pandemic." - https://link.springer.com/article/10.1186/s12889-021-11197-7

"Countries worldwide rely on the COVID-19 vaccine to contain the spread of the pandemic." - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364891/

To be clear, "contained" does not necessarily mean "eradicated". Ebola outbreaks have been contained, but the disease is not eradicated.
The linked Tour is part of the documentation, which at a glance looks extremely extensive. You mention some issues; are you saying these docs are too hard to discover and lacking a good-enough TOC or index ?
Ours have it prominently marked MUTE ->
> They do not appear to form through individual collapses; multi-stage failures lasting hours or days appear to be more common

That's a pretty major factor.
Russel's Teapot?
I'm not sure what you mean. ESD is a big deal with sensors, namely optical FPAs and ADCs for radios. Their voltage tolerance is well established and the ESD generated by humans is easily measured.

It's not that this stuff isn't necessary or we don't understand it so we overreact, it's a calculated risk decision that's currently changing with cheaper launch costs. Satellites are starting to get smaller as the components are being miniaturized much like most tech and launch costs are falling. Small-sats are frequently built in much less strict clean environments and instead of massive controlled transporters, are shipped in crates by Fedex. It just depends on the reliability profile of the mission and the type of instruments in use.
Your post resonates with me, but I dread the yaml configuration. I find it very hard to discover available settings and every module seems to have a slightly different file layout. I’m not a fan of needing the GUI for configuration either.

The constant work to keep things updated is a hassle, requiring python upgrades unavailable in the raspbian distro meaning slow compiles from source (which somehow fails on 3.9 and requires dropping to 3.8).

I would be very happy with something that just works, without constantly needing fiddling and handholding.
100% agreed, as someone who’s automated manufacturing lines, the problem of automation is beyond just robotics. It’s automation with high reliability, yield, less downtime, high throughput, low costs and have to beat humans in the long tail of weird situations. The reason why your home printer can separate sheets of paper and only pick one sheet at a time is nothing short of a miracle backed by thousands of hours of engineering and years of failures. That said, some applications are very easy and we could automate effortlessly (Pick-and-place tools for example in PCB manufacturing).
The only price I watch is 2x6x10 cedar. They were up to $51 back in April, now they're back down to $33. Still seems high but good enough for me to get back to my projects.
"Pressure" sounds like it's in an entirely different ballpark from "runaway inflation"
>But anything just mimimally more complicated or critical gets expensive very fast.

"Critical" i understand, "Complicated" i dispute. Our existing technology has significantly brought down this threshold and it should no longer be a limiting factor.

>There is also a cartel of each medical professionals, manufacturers, insurance companies/public insurance pools and politicians, complete with revolving doors, kickbacks, fake or real -but always suspiciously convenient- scientific data, and exclusionary legal situations. All cementing the status quo and the wealth and standing of all participants (except the patients' of course).

This is what i believe is the real reason. In fact sometimes i think i should spend the rest of my career/life to overturn the status quo with the help of professionals from the Open Source community many of whom would gladly spend their time and money in helping their fellow human beings get affordable healthcare.
Replace Canada with Israel and your argument will be 100% believable.
That is a mischaracterization. It shows the hypocrisy of people disparaging an incredible vaccine, and paying the ultimate price. No-one is celebrating deaths, but they are exposing deep idiocy.
It irks me that they have both votes and reactions.
Just donated, keep up the great work IA - WayBackMachine is invaluable resource :)
But lets all trust them about vaccinations. There is no way these hierarchical government systems ripe for abuse and misinformation, usually lead by CEOs from the medical industry that have paid out billions due to previous lies, could ever mislead us again.
The truth is that we're always in late stage capitalism, except for when we can creatively destroy something well enough to keep our minds off of that reality.
NSO is an Israeli company, which means they need to follow Israeli export laws when it comes to weapons. All of NSO contracts will first go through the Israel Defense Ministry.

The US has a similar process, where companies that sell weapons to foreign governments need to get permission from the US DOD. In this case Marc, Ryan and Daniel did not go through the DOD and that is why they are being charged.
It might give you a year after 3 or 4 doses instead, but I'm not sure it's worth the reactogenicity. Good point though.
Been using the Archive for some 10 years now, both browsing the Wayback Machine and archiving sites onto it (and sometimes using the collections too). This is the first time I'm hearing of any porn on the site. Maybe I should check it out one day when I have too much time; would be interesting to see how it has changed over the last century.
Tesla has their own battery factories too, one is already live at Kato in California:
https://spectrum.ieee.org/tesla-4680-battery

Tesla is also working with Panasonic and CATL to implement their own factories for 4680 cells and scale production.
I think I may be reading/interpreting your comment incorrectly after writing this/digging up these sources -

Whether or not Delta specifically is causing a larger impact on severity of outcomes, we know for a fact that it's more transmissible. And unvaxxed are quite literally dying 99:1 against vaxxed now - mostly from delta. Even if it's less likely to kill/cause severe irreversible organ damage per case, it seems somewhat safe to say the vast majority of unvaxxed are going to get it sooner than later at this point because of increased transmissibility - which will lead to a giant pile of bodies that didn't need to happen.

I would like to think that info alone probably indicates that delta is having a larger affect on the severity of outcomes, but I know there's more to statistical analysis than that. Anyways.

https://www.npr.org/2021/07/16/1017002907/u-s-covid-deaths-a...

https://medicalpartnership.usg.edu/covid-19-staggering-stati...

https://www.cnet.com/health/99-of-covid-deaths-are-now-of-un...

https://www.al.com/news/2021/08/99-of-alabamas-2379-covid-de...

https://www.reuters.com/world/europe/italy-says-99-covid-dea...
I find the list lacking

Having done the job in a previous life there are a lot that are really good out there that don't get a lot of press.

Here's two:

HUMINT - Counterintelligence: The Double Cross System

https://www.amazon.com/Double-Cross-System-Incredible-Turned...

How Bureaucracy and Policy shapes spying: From the Shadows

https://www.amazon.com/Shadows-Ultimate-Insiders-Story-Presi...

n.b. I always find it funny how interested and intrigued yet abhorred so many people are when it comes to spycraft/espionage etc...
80% Clean Power by 2030: Achievable with Benefits
One of these officers is CIO of ExpressVPN. Can you really trust a service with these ties, which also just sold to an ad agency? I personally would not.
Mainly to completely segment off their content (like YT kids) so that while they can have an "Instagram" account, they can't have creepyperson69 sliding into their DMs. It would be similar to what they did with messenger kids.
Except that you can mint the NFT on an infinite number of chains, since the chains are also digitally created. Sure, maybe you can't own one on _that_ chain, but really, who gives a shit?

In the end, this is a less interesting beany babies.
I've never been a FB user.

Years ago, when FB was relatively new, I was very anti-FB, and would discourage everyone from using it due to privacy concerns.

Then a Sudanese friend was staying with me for a few days. He had spent years separated from his relatives who lived in multiple countries, as he was working odd jobs to save enough money for a degree. Through FB, he got to see his nephews and nieces be born and grow for a few years. The amount of joy it brought him was immeasurable.

I realized I was the asshole thinking I knew better than he. If it brought him this much joy, it definitely was worth the loss of privacy. Multiply that by millions.

Today, there may be viable alternatives, but there weren't in those days. At least none that his non-techie relatives could use. FB is what brought about the joy. Nothing else did, despite trying.

FB is a tool. Yes, there are plenty of problems with it, but they require mitigations - perhaps even legislation - not a shutdown. Killing FB, IG and Whatsapp really won't solve anything. Plenty of competitors will eat up the space. It's like saying "Marlboro is the market leader. Let's ban it."
There are now several safe and effective vaccine options that help prevent both death and illness from COVID, to the point it can be considered a preventable disease.

Now that may well change if and when this virus mutates.

But given that reality it does require a level of stupidity to find oneself dead from COVID.
Agreed. Been using home assistant for years, and right now it's probably in the weirdest state as far as configuration/yaml/gui goes. And often times you need to go and edit "read-only" huge json file that contains every single integration instead of individual integration yaml files like it was before.

Nabu Casa (for profit company behind home assistant) made some of the decisions that were questionable at best.
I had an issue with my pixel 2 where something must have shifted in the camera and every photo would blurry on the top half.

Would have been fine to replace it myself but found out that you can not get new replacement parts for the pixel phones and that they are glued up tighter than an iphone with many users reporting that the screen shattered when opening the phone.

Never touching another google product again. While I have had the occasional issue with an Apple product, I have just walked in to the store, they run a few tests and then hand me a replacement on the spot.
Prices will remain high for some goods, but the lumber issue was a supply chain collusion problem.

I believe that the initial shock of high prices was very good for some businesses, and they systematically colluded to sit on inventory. You could physically see it in some places.

But those forces are not as strong as supply and demand so it came back to something approaching reality.

For electronics parts, the pandemic introduced large numbers of speculators who buy and hold parts for gain, those actors create an odd dynamic in the system that would do something like create higher prices, then crash as prices fall and they are forced to sell and the market gets flooded a bit.
How to Measure Burnout Accurately and Ethically
> But the iniquity of oblivion blindly scattereth her poppy, and deals with the memory of men without distinction to merit of perpetuity... Herostratus lives that burnt the Temple of Diana, he is almost lost that built it... Who knows whether the best of men be known? Or whether there be not more remarkable persons forgot, than any that stand remembered in the known account of time?

~ Sir Thomas Browne, Hydriotaphia (1658)
You might like this video of Andrew Sorensen demonstrating Extempore (its included in the software list in the sibling comment)

https://www.youtube.com/watch?v=GSGKEy8vHqg
>Here in Mexico we have an opposite view of this: The majority of developers have spent their professional life doing "consulting" jobs

There's a saying here in Russia:

Can't code? Consult.
Can't consult? Manage.
I see no error. We're going into an incredibly dangerous situation, and it's just considered gauche to realize that, because much of the population has been trained that it's "misinformation" unless it comes from stenographers for the left. The one ray of hope I see is that if we manage to repulse this communist takeover, we may be inoculated against it for at least another few generations.
Ehh I think it would be irresponsible to use all my savings like that, plus you need to buy the land to build on and pay for your current place
My nieces will instantly delete something they post if it doesn't get enough likes right away which seems so anxiety-inducing. :-/
Yes, the intention of Bitcoin is good, and as a research paper, the idea of Blockchain is very genius and interesting. But back to the use case, it must has the basic function first then add more features to it. With low throughput and high fee, it can barely be used widely in normal life, especially for "micropayments". Then what's the point to make it decentralized?

I had some experience with L2 solution, Polygon specifically. As you mentioned, it compromises security or/and decentralization. And I don't think it's a "happy" compromise, since the weak point of a system depends on it's weakest point. If L2 chain has a security or centralization problem, then it can be exploited so that the whole system has such problem.

Even if the blockchain technology can replace current banking system, it's not the solution for problems like monopoly. It just replaced the companies/organizations that are in the monopoly position. Look at the crypto concurrency exchange market and mining farms, you can get a sense.

To make it clear, by "Why not let big company play the monopoly?", I mean monopoly is a bad thing, which would happen if there is no regulation. So in the system of Blockchains, we still need the regulations we need in the current system. I know there are some problems in our political and economical system, but I don't believe Blockchain is the answer.
Wow - I did not expect a real answer.

I've tried two Jinhao models, but I don't think I've tried the 250. I liked them at first, but the inconsistent quality issues annoyed me. I still use one of the Jinhao's, but I swapped the nib.
We are moving all our services OFF vimeo for this exact same reason.

The part you mentioned about stats and info being opaque and then out of nowhere you are blocked out of your account resonates with my experience as well.
I think this is roughly the approach that Liz Warren et all have been suggesting, roughly some sort of platform/participant divide. Applied to amazon it means they can't sell 'amazon basics' products, applied to Apple it'd mean something like they can't offer their own first party apps with higher priority, and applied to Facebook, it'd be exactly along the lines you've pointed out.

Harks back to the antitrust action splitting train lines from steel producers in the 1920s. You need steel to make rail, and you need rail to transport steel, and the steel barons got rich by integrating across these two domains and giving themselves massive discounts compared to participants who were only in one industry and not both.

I'm not sure exactly what the details or enforeement would look like here but I do think it's an interesting line of thought. One thing Matt Stoller says with respect to antitrust legislation is that every company is a unique situation and should be handled as such.
I fail to see any hypocrisy. Wouldn't it only be hypocrisy if you refused the vaccine yourself while encouraging others to get it, or vice versa? Also, there's definitely celebrating death going on in that subreddit.
I don't have a facebook account so no.
Are you referring to something like China influencing the NBA to oust fans supporting pro Hong Kong rhetoric?

https://ftw.usatoday.com/2019/10/philadelphia-76ers-sixers-f...
“Aesthetic” is widely used in the US as well. When I (a US person) see “esthetic” used in this way, it looks like a mistake to me—I associate that spelling with the cosmetics/beauty industry (i.e., "estheticians").
G1 uses a lot more memory than CMS so we can't upgrade that. Is deprecated on 11 but we still use it.
This is false, the mills were expanding and the increased throughout increased supply and prices crashed (along with construction work backing out)

https://www.woodworkingnetwork.com/news/canadian-news/canada...

This was predictable and extremely profitable trade. I made a lot of money this year from this alone.

The price increase was a result of a usual 90 day delivery for new contracted lumber and nobody anticipating people would actually try to build houses in winter time (which they did). A lot of production was wound down and supply contracted out in the future was pulled to earlier dates leaving future contracted lumber demand unfilled leading to price spike and then a crash after extra supply was brought online.

All the information is available but you have to pay for this. There are companies specializing in getting this info for you daily by calling lumber mills.

Fwiw, timber itself is only up about 10% (comparable with 2010 prices)
Is that snark? Do you believe they did this on purpose?