skysight-inc/HackerNews huggingface dataset:
> 67% protective against symptomatic COVID-19 in clinical trials

I'm not a big fan of any of the current vaccines due to their low efficacy against variants, and especially because they trigger an initially weak immune response and are only effective against symptomatic covid-19. The initial weak immune response gives mutations more time to occur, in my rudimentary understanding. If this vaccine is only good at preventing symptomatic infection- does this mean it'll apply more selective pressure on even more variants?

I know that a Marek's situation is highly unlikely with Covid, but won't weak vaccines increase the probability of this happening?

As a young healthy person, I still think natural immunity is the best way to reach some semblance of herd immunity for groups not at high risk. This feels like prescribing incomplete courses of antibiotics.
Seems reasonable. If you want detailed information about the contents of individual cookies that's what developer tools are for. A simple "clear data" button seems far more usable for normal users.
I disagree with basically all of this.

I disagree that cryptography engineers understood viscerally how good a target RNGs were or how viable a PKRNG would be (further evidence for that would be the contortions attackers have to go through to extract enough wire state from Dual EC to mount the most straightforward attacks). I think you can formulate an argument that any major cryptographic primitive is the "lynchpin", and indeed you see people doing that, for instance with the SIMON/SPECK block cipher designs --- block ciphers, after all, are the lynchpin of secure systems.

I agree, obviously, that RSA added Dual EC because DOD demanded it. But most of RSA's revenue didn't come from BSAFE, or even things that relied on BSAFE. They were a crappy token company that bought RSA, then built a bunch of multi-factor authentication stuff that had more to do with IP reputation than with cryptography.

I don't really buy that anybody working inside RSA was absolutely convinced that Dual EC was a backdoor. I sort of don't buy that anyone was really even seriously paying attention. I think people think of RSA as a cryptography company, but that is not at all what RSA was at the time this happened.

None of this matters, really. We arrive at the same place about RSA's culpability. But if you came to HN hoping to find someone to stick up for RSA's decision here, you haven't been paying attention to the tenor of this place. All you're going to get here is hair splitting; that's the interesting conversation we can actually have. There's no viable debate about whether adopting Dual EC was defensible. Even when I was saying I doubted Dual EC was a backdoor, I still didn't think using it was defensible.
Depending on the housing situation being offered.
Marijuana is cool, opium is evil. That's what the media says anyway.
You don't know how many hops there are, so it would mean guessing beforehand, or using a big default (like 64) which means a ton of unnecessary packets for the average route.
> Haven’t most opioid overdoses of the past 5-10 years been fentanyl (or carfentanyl) overdoses?

Well, the data [1] is really mixed depending on the year. It looks like fetanyl deaths really exploded in 2016, exceeding the prescription opioid deaths then.

We'd probably have to examine the source data [2], and go back more in time to get a good feel for it.

[1] https://www.drugabuse.gov/drug-topics/trends-statistics/over...

[2] https://www.drugabuse.gov/sites/default/files/Overdose_data_...
i made this diagram in reaction to this manifesto 8 years ago but unfortunately it doesn't apply as well to version 2.0. still, i'd like to share it again - https://i.imgur.com/ll51WJ3.png
The default for images is signed, not encrypted. A new section of self-modifying or encrypted kernel code would probably trigger some red flags.
Structure Eats Strategy
The Netherlands had fully opened elementary schools since February, UK since March, without any masking and related drama and with barely any distancing. Child Covid-19 mortality has remained very low throughout, even with Delta (grand total of 7 deaths in the UK in the last 6 month).

All the drama around masking at schools seems largely an American phenomenon, where it looks like it's just another flag to signal if you're in Team Red or Team Blue.
> As for non-mineral things like nitrogen, isn't the soil supposed to have an ecosystem that replenishes these things?

Iowa farmers grow corn for money, and Soybeans to replenish the nitrogen. They have discovered enough uses for the "waste" soybeans that sometimes it is worth more than corn, but the original reason soybeans were planted was for the cheap nitrogen.
> 4636 deaths in PRC

That number is completely laughable. It's literally communist propaganda.
> Literally everybody trying to sell you an architecture - good or bad - would probably describe it as "more flexible, loosely-coupled and scalable". [...] If you elide or deny the existence of tradeoffs

"loosely coupled" is a tradeoff; when I hear about an architecture being "loosely coupled", I assume that it allows substituting different components easily, but I also assume that it may be harder to evolve that interface and make use of the full capabilities on both sides. Sometimes I want that (if I'm looking to replace one of those components), but sometimes I want something more tightly integrated.

Similarly, "flexible" is a tradeoff; some frameworks describe themselves as "opinionated" rather than "flexible".
PSA: The much larger crisis is the much larger number of folks who are no longer able to get effective pain relief, thanks to opioid hysteria.

Thank you. That is all.
Git now being a 16 year old technology, might be worth looking at for some.
Every time I've heard some variation of this, the example is always three. I'm more interested in four. Does the pattern follow through? Because I physically can't hold up 3 fingers and my thumb without the pinky going up to, when I do 3, my thumb is holding my pinky down.
> cuts COVID-19 death risk by 4×

And halved severe illness.
If I start counting thumb-1, index-2, middle-3, i can't raise my ring finger without the pinky coming up to properly display 4 fingers up.

If I start counting index-1, middle-2, ring-3, my thumb holds down the pinky to display 3 fingers.

Until just now, I had never tried, so I assume it is a practice thing.

Edit: should have read further in the thread. i'm clearly not the only one
Uh, why? All projects I saw in the early days of M1 (first some script with a modded version, then UTM) were using Qemu to demonstrate the power of Virtualization.Framework (with near native performance). What is Docker doing wrong?
Surely just aesthetic pleasure is worth something? Shall we all live, work and play in brutalist utilitarian buildings unless it can be demonstrated that there are better results from something else?

I used to work at eharmony. One of the biggest complaints we had from users was that paid users were still shown ads. The users hated it, but the analytics showed that we made more money with the ads than without the ads so to hell with the users' experience on the site, we had better results with the ads.
Because, with the proposed system in place, if law enforcement wants to decrypt your data they have to subpoena you, not Apple.

As long as Apple can’t do this client-side scanning scheme, they have to keep the keys to your data on their servers, which means law enforcement can subpoena them without you even being aware of it.
Just one bug fix that multiple people are mentioning is hardly evidence of innovation.
Sure, both browsers have developer tools. This is much more opaque than a Settings menu.
This comment makes me regret to allow employees to open private websites at work. This is why we can’t have nice things.

Some people just are cunts about the freedoms they’re given, and because of employees like you, we end up with antiviruses on laptops and corporate firewalls that block Facebook.

Just because employees feel “micromanaged by a terrible supervisor” who asks to use a separate Chrome profile to not mix cookies with work.
> From a purely technical perspective, Dual_EC_DRBG is still secure.

I think that depends on the techniques you're thinking of. The usual way of proving such a system is secure is to reduce a break to a solution of a bedrock problem like discrete log, and according to the second reference in the OP, "Cryptanalysis of the Dual Elliptic Curve Pseudorandom Generator", no such proof was provided in this case. I would say that without such a proof, it's not "technically" secure.
> Who does that benefit exactly? Just some sort of vengeance?

The rule of law, for one.

And everyone, for another. The precedent this sets for other pharmaceutical companies is horrible. Lie about the downsides of your drug, aggressively extract profits, stash the money overseas and discharge your liabilities through bankruptcy is an awful playbook.
Week in Review: Texas Abortion Law
>Pharmaceutical companies are evil

I've lost count how many institutions, governments and corporations have disappointed me over the last year.

But Moderna and Pfizer are not among them.
What the hell happened to Google? Who are these complete idiots running the show?
What someone says or writes could provide information useful for predicting the future. That by definition has meaning.
This also applies to how we work too.

Everyone is having a blast doing SCRUM until some manager decides it would be cool for them to keep track of how many story points the team completes as some sort of performance metric.
And with two’s complement, we can even have negative numbers!
Sure, which is only true if the maker actually gains from the greater market share indirectly.

This is almost certainly only going to be true in a tiny number of cases - e.g. photoshop, where commercial users generally don’t use pirate copies, and do get sued if they are found to.
We bought our second Synology NAS three years ago, an Intel four bay with SSD caching. It's fantastic. Some of Synology's ancilliary software is buggy or has missing features, but as a backup intermediary (it backs up our backups to cloud storage) and file server it's been flawless. Also the apps available for multiple platforms make integration with phones and tablets easy as well as latop and desktop.
Yes, now we're talking! Enough of the "we've accomplished so much" rhetoric already. Thank you!

> What do many people do when they are in a state of despair, the state your messaging is portraying?

They get fearful and then they get angry and then they demand changes.

> I suggest toning down the fear mongering rhetoric

Is is rhetoric if it's accurately portraits the state of things? Because all the statistics I've mentioned are documented scientific facts. Is it fear mongering to call out the state of things and to remind people what the stakes really are?

Maybe? I don't know. But I don't think so.

> Everyone knows global warming is a thing, the US government isn't ignoring it.

The US government is still subsidizing fossil gas and is issuing permits for drilling, both on-shore and off-shore. Nothing is happening besides lip service. Little progress has been made and as soon as the Republicans are back in office, all of that will get reversed. Because even in the US, one of the richest countries in the world, more than 35% don't consider global warming to be a thing. There are lots of people that haven't yet realized that it is a thing. And even if they have realized that it's a thing; they either don't know how big of a thing it is or they refuse to speak out - both because they fear to be ridiculed and because they don't want to face the fact that we're headed for disaster.

In our times, there is no other topic as urgent as getting a hold of climate change.

> I'm not sure why you are selling it.

I want for people to acknowledge that our predatory ecosystem exploitation has brought us to the brink of an existential crisis for all of humanity and that we have to get our shit together, as a species, to address this problem.

Because, you know, I'm scared shirtless. I lie awake at night, of fear for the lives of my children and their children. Because they will not inherit a place to live. They will inherit a place to die. There will be millions and millions of people on the run, desperately trying to get somewhere they're not scorched by the heat and forced to starve to death. Their migration will destabilize governments and they will be welcomed with scorn and hatred. Our acidic oceans will be fished empty, empty and lifeless, our fields will be barren and dry and and what little food there is will be barely enough to feed the industrial countries. If we continue to act like we currently are, in forty years time there will be hunger and riots and strive and war. Globally.

Because nothing is happening that would change the course we're currently on. There's a huge iceberg (A metaphorical one. The actual one has already melted, since the arctic is now ice free in summer) that we're headed straight towards and everyone is busy arranging the deck chairs for the orchestra.

I want people to be afraid and fearful and to get angry and to demand change. Not climate change, the other kind of change. The kind of change that averts climate change.
At least we know that secrets never leak out.
The brand is ultimately in the minds of consumers, and if you followed discussions, many of them (and press) had the same impression that it is inconsistent with Apple positioning wrt. privacy.

While household analysts get things wrong all the time, companies are not infallible, including Apple.
Peas are the seeds.

There are some plans that need an animal to digest the seed covering, but not all plants have that as part of their reproduction cycle. (I'm not sure what pea's natural cycle was)
Which is why it’s mystifying. If she was running an obscure distro, compiled from source after checking each line for nefarious code like everyone should do, and after having prepared the hardware (carefully consulting the compatibility list), that would be normal.
> If the user caused the problem, telling them the problem should make it easy for them to fix it.

Ever shipped consumer software?
Am I misunderstanding this from the paper:
"The proportion of individuals with COVID-like symptoms was 7.62% (N=13,273) in the intervention arm and 8.62% (N=13,893)" That really seems like a pretty small overall difference in the two groups in terms of those getting infected.
Things to look at when collecting NFT’s
Until you get infected with a novel virus and your immune system freaks the fuck out trying respond to it and you wind up dying from a cytokine storm.
Not intended to start a long thread:

How do I start with Scheme and the moder R7RS standard?

Books, tutorials, courses ?

Thank you.
C'mon. Anyone in the last fifty years believing that this time they have made opiods non-addictive? I mean, let me know if those people truly exist because I have one bridge to sell to quite a lot of them.
Johnny Harris has a pretty good video about this.

https://www.youtube.com/watch?v=SrDEtSlqJC4
My most commonly used math functions are (in no particular order):

- Average

- Medium

- Max / Min

- Length/Count

- Add / Increment

- Subtract / Decrement
Individual developers can learn, but they are replaced by new developers that have not learned. Sure, this specific instance of copilot is not the best, but it sure feels to me like people are discussing the concept of it, not the exact implementation right now.
> I know that a Marek's situation is highly unlikely with Covid

Someone told me about Marek at work but I didn't find anything related to COVID vaccines, good or bad.

Do you have some sources that speak about it?
The same idiots looking ad and data mining revenue, and then seeing what their customer's demands are.

Their customers being the ones who are buying services from Google.

Not you.

You're the product.
Requiring Masks in Schools Has a Downside
Lemur Pro:
Fit and finish is a A- for PCs (B compared to a Mac) Solid build, no super weird stuff on the Lemur Pro. The silkscreen for one of the USB ports says 3.1 but it's 3.2. The webcam has a little lip. Trackpad is pretty clickey (ive been used to apple synthetic click)
Money counting as well:

"How money is counted in different countries"

https://www.youtube.com/watch?v=g87HVlu55mQ
It's one of these mystery numbers:

$ man printf
[goddammit you stupid computer]
$ man 3 printf
That's interesting. How can one differentiate the two then? Does the wrist position matter? A thumb out with the wrist twisted so the thumb is at an angle indicates "1", but a forward thrusted wrist so the thumb is pointing up and towards the person mean "yes, good job"? Is the second meaning lost entirely to the barman?

If you had flashed OK hand gesture, would the barman have poured 3 pints, or thought you were a member of a fringe group?
Well, clearing it depends on whether the app is designed to handle that. Since iOS gives app developers the option, we must assume that what is in that area is not designed to be cleared.

I agree it would be nice to see more detail about it, but for almost nobody is thus actually relevant.
It's certainly true that in most democratic countries, older (and higher risk) people are a powerful voting block. From a moral perspective it also seems good to protect our elders. I would hope that when I am old, the younger generation does not just put me out to pasture.

I have heard many advance the solution that older/high risk people should just stay home, but that's not really feasible either. Many elderly people live alone. Everyone needs basic supplies, medical care, social interaction etc, and each of these presents a vector for infection.

I'm sure there is an optimal solution where the most effective interventions are deployed to protect the vulnerable, without massively inconveniencing everyone. There is no reason we should accept 1000+ deaths per day as normal. The problem is that neither side in this debate seems remotely willing to compromise and/or do the experimentation needed.
I really want more info on the injection: "a needle-free device pressed against the skin, which creates a fine, high-pressure stream of fluid that punctures the surface and is less painful than an injection"

edit: in action: https://youtu.be/MGvSWtuu4z4?t=86
>Normally you would expect effective contagion control measures to have an exponentially larger effect at a societal level than it does at an individual level

Isn't this dependent on the assumption that the risks are reduced uniformly across society? Lockdowns/quarantines are the obvious counterexample. Someone going into complete lockdown reduces their risk to practically zero. However a small group of people doing that won't have much effect on the societal numbers. Therefore the societal reduction is much less than the individual reduction until that R value drops low enough.
But "Read forward from there" is often just way too much text, with no clear delineation between different topics other than reading it. Reddit encapsulates topics into their own spaces that can live outside of an ever-increasingly long scrolling text screen.

I regularly get so far behind on channels in an 11 person server that I just give up on reading whatever I missed that day. If Discord and Reddit can serve functionally identical purposes in your life, that's fine, but to deny that they have any functional differences to anyone is just provably false.
Remind me of what natural immunity is supposed to be good for, if not for preventing disease.
Don't have you tell you this, and not disagreeing with you.. but ... Farming is mining. It's extractive. Every bit of plant matter we ship off our farms in the form of food is carbon and nitrogen that is no longer in our soils. I concur most farmers don't give a crap. But even the ones who do, it just slows it down, doesn't stop it.

We run a little market garden. I follow all sorts of agronomy feeds and information and then read and watch what other growers are doing. Even the most "regenerative" and "ecological" growers don't seem to get it... There's no free lunch. I've read analysis which points out that there is not even enough manure produced on the planet to fertilize our farm fields without chemical additions, and don't even think about compost, it's not even close... and all the soil retention and cover cropping one does will only slow down, not reverse, top soil loss. If you're not losing carbon in your soils, it's because you're bringing it in from somewhere else, and it's lost there.

So many permaculture types trying to imply that what works for them in their backyard city gardens works on a large scale. It does not. I learned the hard way.

I see "no till" market garden growers whose solution is basically to dump 100 cubic yards of compost on their beds each year and plant into that instead of tilling. This is the Richard Perkins etc. method, and it's intellectual dishonesty. All that compost comes from somewhere and that place now in turn has a carbon deficit.

At least, this is all the case until we can find a way to efficiently extract CO2 from the atmosphere and turn it into solid soil ammendment. Trees and cover crops can't do it fast enough.
I’m going to try this later. I noticed the slowdown switching from a relatively weak Linux server to my M1 Macbook and had already accepted the disappointment of the M1 not being so great after all.
You have to change the profile from "headphones" (high quality audio) to "headset" to have a microphone. It's a matter of a few clicks.

I'm just pointing out that Apple was doing something different. As far as that being not viable for Linux to take off... well, I respect your opinion.
Are you an epidemiologist, or should we consider your credentials to be merely "young healthy person"?
Ha. Yeah, the number one thing in the US hurting small business is lack of universal health care. It has been a problem my entire adult life.
Let’s recap. You mentioned that (paraphrasing here) that is difficult to near impossible to get hired in the south without a southern accent and a love for Jesus. I mentioned that wasn’t my experience. You take my response and turn into an anti-trump rant. Again, I mention have never found the south inhospitable, but acknowledged your opinion. I also mention that most people I know ignore stupid signs (because they do). Apparently you don’t or perhaps “can’t”—and that’s your reaction to own. Then you end this with some sort of assumption that the tiny percent of idiots that might place Trump signs in their yards are somehow representative of an entire region of the country. Including wrapping me into this group because I simply choose to ignore the idiots. You finish your obviously thin skinned rant by trying to project it on to me.

So again I say, I find your initial premise about employment difficulties in the south for folks without a southern accent or without a Christian faith to be be completely counter to my experience.

As for the rest of your diatribe and opinions, I think I am just going to ignore them. Frankly, it reminds me just a little too much of the kind of attitudes and binary thinking that cause certain people to post “Trump country” signs in their yards.
One big cost would be changing all the documentation ... OpenBSD does that...
Seems like Toptal? Also, the FAQ and the whole website is oriented only towards clients on the one side - those who are in need of devs. What about the clients on the other side - the devs? Can you share what percentage they take from devs?
The author gets so close to the productive answer regarding TODOs, it's frustrating to see the conclusion be "...so never add TODO comments at all."

So what, after creating the issue for the future, the person implementing it has to start over navigating the code?

And the next person working on the code (who might not know about that issue) might stumble across the same obstacles as the original author who went on to file the issue?

I think in any multi-programmer project, the bidirectional link code<->issue needs to exist.