skysight-inc/HackerNews huggingface dataset:
It makes sense, doesn't it? The playing field has changed completely since the beginning of the pandemic. New variants are much more transmissible, more is known about the virus, and vaccines are widely available for the countries who bought them. Strategies that were once effective for zero covid now only work to suppress cases to a low enough level until the population gets vaccinated and covid becomes much less of a threat.

Did anyone in New Zealand really plan on closing down the country forever?
Heavy duty deployment tooling is a hobby of its own. :-)
Has this been updated for the delta variant which is estimated be twice as likely to cause hospitalization?

https://www.politico.eu/article/delta-coronavirus-variant-do...
80 years is longer than the average life span of most highly developed economies. In short: It is a lifetime. It seems long to me.

And 80 years is roughly 50% of all years of industrialised economies that started around 1850. Recall that the world economy had zero growth per capita until the industrial revolution started around 1850.
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Definitely could have been that. Thought it was some freaky subliminal messaging lol.
Reframing the discussion in terms of just server seems to be deliberately missing the point, since the issue under consideration is the new pricing model for Docker Desktop. Which is 100% about developer experience on OS X and Windows.
It's far simpler than this. If you get the basics of http, the only thing you need to know is what is the 'proxy' a proxy (stand-in) for? the client (forward) or server (reverse).

If people used the names client proxy and server proxy it would be much clearer. Calling one forward and one reverse means you have to know the order of popularity of usage which is dumb thing to settle on.
Maybe you can tell me what you think it means and what I think it means then. Investopedia and my work in finance both seem to support my take.
Xiaomi to launch electric car business with $10B investment
Reviewable | Lead Product Designer | REMOTE (US only), full-time | https://reviewable.io

Hey there! Reviewable is growing quickly and we're looking for an experienced Product Designer to help us continue to delight developers around the world.

Reviewable is a code review tool for GitHub pull requests that makes the process of serious reviews thorough yet efficient. It's not for everyone but the teams that need it swear by it. However, as Reviewable has grown organically over the years its design hasn't kept pace, and the most common complaint from potential users today is that the UI looks confusing and the workflow feels foreign. That's where you come in!

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The goal is certainly the reverse: get the full return, and demonstrate that it's not just your name and address book that are helping.

And yes, this requires you to be very self-reflecting and open to the possibility of being wrong, but is it truly so hard to imagine that someone would rather know than not know?
Extremely wide support for one.

CMake is the only build system with first class support for all of the major platforms - and those platforms' default tooling.

I can't tell you how much Visual Studio adding CMake support reduced the barrier to support cross platform C++ projects.

I'm a Linux user myself, but I interact with a lot of Windows developers and telling them to leave Visual Studio and use command line tools usually just means they won't be happy about working on a project.
Frame.io | Backend/Frontend/SRE/Security| Full-Time | NYC or Remote

Frame.io is changing the future of how videos are made by helping over 1 million creative professionals seamlessly collaborate from all over the world.

We’re backed by Accel, FirstMark, Insight Partners, SignalFire, Jared Leto, and a host of other amazing investors. Our market-leading product is used and loved by companies such as Turner, Disney, NASA, Snapchat, BBC, BuzzFeed, TED, Adobe, Udemy, and many more.

We’re in an exciting period of growth and are always seeking extremely talented and passionate individuals who share our vision for helping visual content creators produce their best work.

Tech: Elixir, JavaScript/TypeScript, GraphQL, Kubernetes, Go, Terraform, AWS

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Wearing a helmet in a car is a PITA. Getting vaccinated causes literally no ongoing inconvenience 24-36 hours later. It's effectively a cost-free intervention with enormous upside in terms of protection from death and hospitalization. Helmets are better compared to interventions like masks and social distancing, as they must be used constantly.

Edit: taking your analogy less literally, it seems the issue here is the socially acceptable level of risk. The health risks of covid are demonstrable and apparent. If we can mitigate those risks by ~90% with no ongoing cost, then that intervention makes sense. On the other hand, if additional interventions mitigate it by only an additional 5%, then those may not be worth the trouble.
I agree that its helpful and you notice Ive been firmly on the side of everybody stealing it - which is why "pretty much every language has that" rather than "oh, cool, that's a really nice feature and it's interesting to learn where it diffused from" was such an oddly dismissive response to Walter and I enthusing about it.
I don't have numbers on "old vs young" hospitalization. I'd have to do some more googling for that and I need to get back to work.

However, regarding efficacy on the delta variant, from here [1]: Data so far suggests efficacy rates of approximately 67 percent for the J&J vaccine, 66 to 95 percent for the Moderna vaccine, and 42 to 96 percent for the Pfizer-BioNTech vaccine.

Seems like pretty good efficacy to me.

[1] https://www.healthline.com/health-news/heres-how-well-covid-...
I was able to get podman setup in WSL2 pretty easily following this:

https://www.redhat.com/sysadmin/podman-windows-wsl2
There actually is!

Two studies in Brazil have shown a pretty significant reduction in hospitalizations in a RCT of fluvoxamine. More data obviously required.

Plus there has been more work on other treatments, but most are pretty expensive.

https://www.vox.com/future-perfect/22619137/fluvoxamine-covi...
> I just want a VM (or similar)

Especially something like WSL2, which Docker Desktop for Windows uses in the latest releases. I know that is a VM (or similar) but the way it uses memory on demand, rather than reserving a huge chunk of your memory up front, makes a huge difference from a typical VM experience.
I recall an interview with someone in charge of the Social Security Administration about how they were constantly asked about various issues surrounding SSNs and he had to constantly respond

"It wasn't meant for this, it wasn't built for it, it's not used in a consistent way that we could do that, and I'm not sure you want the Social Security administration to be in charge of that, that's not what we even do..."
Which actions do you think were for show?
Medly Software Systems LLP | Multiple Roles | Pune, India | Full-Time

Medly is a digital pharmacy that was founded by second-generation pharmacy owners with decades of experience in the industry. By combining the personal relationship you’d expect from a corner drugstore with the efficiency of a national pharmacy, we aim to make healthcare more efficient and enjoyable.

We are hiring for following roles:

- Associate Backend Developer (Kotlin, Micronaut, AWS Lambda)

- Associate DevOps Engineer (Terraform, AWS)

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- Senior Backend Developer (Kotlin, Micronaut, AWS Lambda)

- Senior DevOps Engineer (Terraform, AWS)

- Senior Frontend Developer (React, Redux)

- Software Development Manager / Engineering Manager

You can send me resumes at shirish.padalkar[at]medly.com or apply directly at https://apply.medly.careers/
I recommend mass vax and this point is one of the main points I use. But I agree with you that sadly, this danger is not well known.
They don't discuss how they'll be balancing the books without subscription charges? That's the interesting part!
“Get Off the Floor” and Other Career Advice
I lived that series. I think his books depend on how much time you can devote to them. If you can read for hours on end the. They are great, you can really immerse yourself in them. They are not books you can read a few pages of every now and then.
Gibson's book Distrust that Particular Flavor of some collected columns is worth a read.
Considerably greater risk of myocarditis and other heart issues from infection than the vaccine. See Fig 4 of [1] in particular.

When reading that chart, keep in mind that lymphadenopathy is just swelling of the lymph nodes, and is an expected and not-serious effect of the vaccine; it's a sign that an immune response is being triggered.

[1]: https://www.nejm.org/doi/full/10.1056/NEJMoa2110475
Your comment struck me as odd but then I thought maybe you live in the US or a country like that with a language largely used by everyone. In France and Belgium and Europe it's really common for museums to offer audio guides. Which are either headset with a radio receiver that plays whatever the radio emitter is cycling or a headset with a small media player that plays tracks when you enter a room or switch a button.
> there's little/no treatment for the infection resulting from this virus.

This is not true. Since the beginning of the pandemic front line doctors have been successfully reducing hospitalization and death through early treatment with antivirals, corticosteriods, and antithrombotics.

[1] Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19)
https://scholarlycommons.henryford.com/cgi/viewcontent.cgi?a...

[2] Timing of Antiviral Treatment Initiation is Critical to Reduce SARS-CoV-2 Viral Load
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.1...

[3] Clinical outcomes after early ambulatory multidrug therapy for high-risk SARS-CoV-2 (COVID-19) infection
https://rcm.imrpress.com/EN/article/downloadArticleFile.do?a...

[4] Early multidrug treatment of SARS-CoV-2 infection (COVID-19) and reduced mortality among nursing home (or outpatient/ambulatory) residents
https://www.sciencedirect.com/science/article/abs/pii/S03069...

[5] Multidrug treatment for COVID-19
https://www.jstage.jst.go.jp/article/ddt/advpub/0/advpub_202...
Considering that central banks for highly industrialised, wealthy nations normally move in 25bp increments, moving from -50bp to -50,000bp seems... well, a lot of central bank meetings. Are you proposing run away deflation? We have never seen it since the industrial revoluation stated. If the risk is real, why aren't we seeing more academic papers about this subject?
Indeed. Interestingly enough, they support Login.gov (a USDS/18F/GSA identity project) as an identity provider service [1] :)

I keep poking government agencies who don't support it. Some are easier, some are harder. Some I have to go talk to legislators about appropriations to extend their applications to include the support. A necessary schlep.

[1] https://secure.ssa.gov/RIL/SiView.action
Detecting Abnormal Chest X-rays using Deep Learning
>California Community Colleges officials declined to say whether any financial aid was disbursed to fake students

Well we all know what they'd be happy to tell us if they didn't. So by process of elimination...
Anyone have one? I'm used to Apple displays and Apple track pads. How do Framework laptops compare? How is the keyboard?
New electric bike drive system requires no chains or belts, ride-by-wire
I am not sure, this might be remote until the pandemic becomes more manageable.
> You get half a Xanax, go home, go to sleep

Wait, you get the Xanax afterwards? I'd need several Xanaxen before being able to walk into the procedure.

> I might not be able to relate to what an anxious person might go through.

Yeah, I freak out even when I get my blood pressure taken. As soon as I hear them rip the velcro on the cuff I can feel my pulse rate just about double. And then they think I have high blood pressure and I have to explain that, no, when I take it at home it's actually kind of low. Adrenalin is a heck of a drug.
The question is how useful variant-specific boosters are at this point in time, though. As I understand it there are two things working against them. Firstly, one of the main ways Delta seems to beat vaccination is by replicating more efficiency before the immune system can respond, and tailoring the vaccine more specifically to it won't really help with that. Secondly, a booster for a very similar variant might just boost the existing immune response for the previous variant rather than creating new, more specific antibodies ("original antigenic sin") - this is apparently one factor limiting the effectiveness of flu vaccines.
Egan
"The mRNA is only a piece of the spike protein, and does not enter the cell's nucleus."

and with the AZ vaccine, due to the vector chosen, supposedly it (spike protein) does enter the nucleus. Oops.

(note I'm not suggesting the AZ vaccine causes any alteration of our DNA)
That "80-90%" might have been a thing before COVID, but now more and more facilities are running at capacity.

Even in Washington (70+% with one shot) and Seattle (83% one dose, 77% complete series) a number of hospitals are full enough to be cancelling elective surgeries again.
That's not at all how I remember it! (j/k). I think it's a good reminder that our impressions of the world around us are personalized and that they may not be representative of reality.

P.S. Sorry if I reopened an old wound!
(50 cm)
That would be a violation of the general act on equal treatment (introduced 2006), and hence referred to the state's attorney's office. Scientology does not enjoy the protection of religion or worldview because the organisation is under surveillance from the federal office for the protection of the constitution because of their politically motivated crimes.
NBA 2K22: Dribbling gets major changes, tons of new moves
Why do so many discussions around this have to devolve to reasoning against absolute straw-men arguments?

The point wasn't for "everybody" to stay at home but to expand "everybody who can" to the highest possible number, by removing economic and other barriers.
Step 1) Release open source free software

Step 2) Get millions of people aboard

Step 3) Clamp down, raise prices, make people pay for their mistake of relying on 'free' services/products.

If you change Step 1) to Subsidize services, then you get Uber/Lyft. This also applies to drug trading (first time is free!).

It gives unfair advantage to companies that have deep VC-lined pockets and a huge pool of money to spend. It raises the critical barrier for the small-guy to compete in this landscape. It also makes it easy for these companies to wipe out competition by undercutting them. This is just cheating.
This is false. We don’t know this for a fact currently. Best assumption at best.
Side note - I think they’re asteroids and not raindrops. Dino(saurs) being the theme.
Protectli. They are fanless and use 7th or 8th gen Intel laptop processors. Uses regular laptop memory and mSATA/NVMe for storage. If you run OpenWRT on them they are blazing fast, but its a regular x86 box with an HDMI port so you can run a full GUI if you want.
I too would love having a discrete graphics chip.
This is a very large and carefully executed study. From the conclusions:

> A sample of more than 30,000 people is “too big to ignore”, according to Ring.
It’s interesting how some challengers (Snowflake, for example) use the Clouds’ go to market teams to power distribution and sales, so these platforms extend beyond just tech infrastructure.
Presumably university libraries are also forking over much less, since the increased publication fees are replacing drop in subscription fees?

So part of it is the university just needs to figure out how to appropriately reallocate it's resources?

I wonder how often the university employers of article authors pay these publication fees, and if those budgets are going up? (If university library subscription fees are not going down, then that's another sort of mystery to look into).
The Sia Foundation | REMOTE | https://sia.tech

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Marc Lore wants to build a utopian megalopolis
This isn't a protest, it's a tantrum. Comparing it to a protest is an insult to protestors. If you've seen what the mods behind this are saying, the intent behind all becomes VERY clear.

I think this entire event and the way all parties have reacted to it is extremely embarrassing.
Just to clarify I was talking about the Pfizer and Moderna mRNA vaccines.

AstraZeneca’s vaccine uses adenovirus-vectored technology, which is different [1].

[1] https://www.prevention.com/health/a35118263/astrazeneca-vs-p...
I don't think the vaccines have been a failure at all, they still prevent hospitalization and deaths from COVID quite well, and breakthroughs were predicted to be fairly common from the start. I think what has been a failure is the public messaging about the vaccines and COVID in general. That said, I do agree that we need to move on from the fear based approach to life many have held on to even after getting vaccinated.
If you find unnecessary animations like the background rain annoying you might consider setting prefers-reduced-motion.

The site respects it.
TBH I don't really think it's something easy to do. You will probably have to go around somehow. Arguing about facts seldom works. Maybe he has someone he listens to so it's time to find out whom it is.
If you consider "add to quality of life" a synonym for marginal utility I think you may be in agreement.

Yes, $10 buys the same Mcdonald's lunch regardless of how much money one has, but two people, one with $0 and one with $1bn in net worth will be excited about that lunch to very different degrees.
Confluence vulnerability (CVSS 9.8): Unauthorized access and remote code exec
Seam (YC S20) | Backend & FullStack | SF, Near-Remote | https://getseam.com/

Seam builds an API for all the IoT devices around us. A mix of Plaid/Stripe, Seam lets software developers connect and control WiFi locks, thermostats, elevators, EV chargers, and more.

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SEEKING WORK - Senior Front-end / React developer, UI/UX designer

I'm a Computer Scientist, and a self-taught UX/UI designer with works featured in online galleries.

The last 15 years I've been designing and developing websites and applications from back-end to front-end, from architecture to UX/UI design, on various stacks.

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bartus.csongor@gmail.com
Typically antibody-producing B-cells are screened for binding to self-antigens during their development inside bone marrow, where if they were the type to produce autoantibodies then they would be destroyed before even entering the body.

Antigen matching is rarely 100% exact though, and it's possible that an antibody match could have partial binding to existing normal body proteins, especially if the virus is using those proteins itself. Hypothetically that would lead to an autoimmune response in addition to an immune response to the virus.
Forgive me for pattern-matching your political leanings; it's insufferable to deal with a dozen variants of "it's just a flu" mutated from the dear leader's mouth over here. You're right, real dialog on scientific matters is getting impossible, because people can't do basic research.

If you'd like to read up on mRNA vaccines, here's an article from the pre-COVID days, before something as simple as a scientific advancement to fight disease became so politically charged.

https://www.nature.com/articles/nrd.2017.243

Ecological activists, by numbers, are a round off error in the debate over this vaccine. It is absolutely tainted with politics, as the majority of anti-vaxxers land on one side of the political spectrum. I know some. It's everything from "it's the mark of the beast" to "I'm not so sure about this". What really underlies it is a deep, irrational selfishness that doesn't want to do a damn thing, even if, and especially if COVID doesn't seem that risky for that person. That whole line of reasoning is a fail. People who want the pandemic to be over know that vaccination is the only way. Sitting on your ass, no matter what is in your head, and being another vessel for this shit to mutate is actively prolonging it.

So yeah, I absolutely pounce on ignorant people who are prolonging this.